go-ontology

Ontology comparison

Left

• Ontology IRI: http://purl.obolibrary.org/obo/go/extensions/go-plus.ofn
• Version IRI: http://purl.obolibrary.org/obo/go/releases/2026-07-26/extensions/go-plus.ofn
• Loaded from: file:/__w/go-ontology/go-ontology/src/ontology/go-plus-lastrelease.owl

Right

• Ontology IRI: http://purl.obolibrary.org/obo/go/extensions/go-plus.ofn
• Version IRI: http://purl.obolibrary.org/obo/go/releases/2026-08-18/extensions/go-plus.ofn
• Loaded from: file:/__w/go-ontology/go-ontology/src/ontology/extensions/go-plus.ofn

Ontology imports

Ontology annotations

Removed

• versionInfo “2026-07-26”

Added

• versionInfo “2026-08-18”

‘de novo’ NAD+ biosynthetic process from L-tryptophan http://purl.obolibrary.org/obo/GO_0034354

Added

• ‘de novo’ NAD+ biosynthetic process from L-tryptophan term tracker item “https://github.com/geneontology/go-ontology/issues/32456”^^anyURI

• ‘de novo’ NAD+ biosynthetic process from L-tryptophan never in taxon Schizosaccharomyces pombe

• ‘de novo’ NAD+ biosynthetic process from L-tryptophan SubClassOf not (in taxon some Schizosaccharomyces pombe)

(+)-larreatricin biosynthetic process http://purl.obolibrary.org/obo/GO_1901709

Removed

• (+)-larreatricin biosynthetic process conformsTo metabolic_process.yaml

Added

• (+)-larreatricin biosynthetic process conformsTo biosynthetic_process.yaml

(25S)-Delta(7)-dafachronate biosynthetic process http://purl.obolibrary.org/obo/GO_1902056

Removed

• (25S)-Delta(7)-dafachronate biosynthetic process conformsTo metabolic_process.yaml

Added

• (25S)-Delta(7)-dafachronate biosynthetic process conformsTo biosynthetic_process.yaml

4’-phosphopantetheine phosphatase activity http://purl.obolibrary.org/obo/GO_7770095

Added

• Class: 4’-phosphopantetheine phosphatase activity

• 4’-phosphopantetheine phosphatase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32389”^^anyURI

• 4’-phosphopantetheine phosphatase activity created by “ai4c-agent”

• 4’-phosphopantetheine phosphatase activity creation date “2026-07-30T17:40:49Z”

• 4’-phosphopantetheine phosphatase activity database_cross_reference “EC:3.1.3.110”

• 4’-phosphopantetheine phosphatase activity database_cross_reference “KEGG_REACTION:R10748”

• 4’-phosphopantetheine phosphatase activity database_cross_reference “MetaCyc:RXN-24222”

• 4’-phosphopantetheine phosphatase activity database_cross_reference “RHEA:68328”

• 4’-phosphopantetheine phosphatase activity has exact synonym “pantetheine-4’-phosphate phosphatase activity”

• 4’-phosphopantetheine phosphatase activity has exact synonym “phosphopantetheine phosphatase activity”

• 4’-phosphopantetheine phosphatase activity has_obo_namespace “molecular_function”

• 4’-phosphopantetheine phosphatase activity id “GO:7770095”

• 4’-phosphopantetheine phosphatase activity exactMatch RXN-24222

• 4’-phosphopantetheine phosphatase activity exactMatch 3.1.3.110

• 4’-phosphopantetheine phosphatase activity exactMatch 68328

• 4’-phosphopantetheine phosphatase activity definition “Catalysis of the reaction: (R)-4’-phosphopantetheine + H2O = (R)-pantetheine + phosphate.”

  • database_cross_reference “EC:3.1.3.110”

  • database_cross_reference “PMID:18678912”

  • database_cross_reference “PMID:35896750”

  • database_cross_reference “PMID:27322068”

  • database_cross_reference “RHEA:68328”

• 4’-phosphopantetheine phosphatase activity label “4’-phosphopantetheine phosphatase activity”

• 4’-phosphopantetheine phosphatase activity SubClassOf phosphatase activity

• 4’-phosphopantetheine phosphatase activity SubClassOf has participant some water

• 4’-phosphopantetheine phosphatase activity SubClassOf has participant some pantetheine

• 4’-phosphopantetheine phosphatase activity SubClassOf has participant some hydrogenphosphate

• 4’-phosphopantetheine phosphatase activity SubClassOf has participant some D-pantetheine 4’-phosphate(2-)

ABC-type cadmium transporter activity http://purl.obolibrary.org/obo/GO_0015434

Added

• ABC-type cadmium transporter activity term tracker item “https://github.com/geneontology/go-ontology/issues/20824”^^anyURI

• ABC-type cadmium transporter activity broadMatch 12132

• ABC-type cadmium transporter activity comment “Note that RHEA:12132 represents both the ABC and the P-type cadmium transporters.”

ATP-dependent folded protein transmembrane transporter activity http://purl.obolibrary.org/obo/GO_7770098

Added

• Class: ATP-dependent folded protein transmembrane transporter activity

• ATP-dependent folded protein transmembrane transporter activity term tracker item “https://github.com/geneontology/go-ontology/issues/32394”^^anyURI

• ATP-dependent folded protein transmembrane transporter activity created by “ai4c-agent”

• ATP-dependent folded protein transmembrane transporter activity creation date “2026-08-04T00:40:41Z”

• ATP-dependent folded protein transmembrane transporter activity has exact synonym “ATPase-coupled folded protein transmembrane transporter activity”

• ATP-dependent folded protein transmembrane transporter activity has exact synonym “folded protein-transporting ATPase activity”

• ATP-dependent folded protein transmembrane transporter activity has_obo_namespace “molecular_function”

• ATP-dependent folded protein transmembrane transporter activity has_related_synonym “folded protein translocase activity”

• ATP-dependent folded protein transmembrane transporter activity id “GO:7770098”

• ATP-dependent folded protein transmembrane transporter activity definition “Enables the transfer of a protein in its native, folded conformation from one side of a membrane to the other, coupled to the hydrolysis of ATP and without unfolding of the substrate, according to the reaction: ATP + H2O + protein[side 1] = ADP + phosphate + protein[side 2].”

  • database_cross_reference “PMID:32042153”

  • database_cross_reference “PMID:40410623”

  • database_cross_reference “PMID:31988523”

• ATP-dependent folded protein transmembrane transporter activity comment “This activity is exemplified by the mitochondrial inner membrane AAA-ATPase Bcs1 (BCS1L in mammals), which translocates the folded, 2Fe-2S-loaded Rieske iron-sulfur protein from the mitochondrial matrix across the inner membrane during respiratory complex III assembly. Unlike most AAA+ protein translocases, the substrate is not threaded through an axial pore in an extended conformation; in Bcs1 it passes between two aqueous vestibules separated by a seal, in an airlock-like mechanism that preserves the membrane permeability barrier. Do not use this term for the separable channel and motor activities of multi-subunit translocases; for those, consider ‘transmembrane protein transporter activity ; GO:0008320’ and ‘protein translocation chaperone activity ; GO:0140388’.”

• ATP-dependent folded protein transmembrane transporter activity label “ATP-dependent folded protein transmembrane transporter activity”

• ATP-dependent folded protein transmembrane transporter activity SubClassOf protein-transporting ATPase activity

ATP-dependent protein-RNA complex displacement activity http://purl.obolibrary.org/obo/GO_7770106

Added

• Class: ATP-dependent protein-RNA complex displacement activity

• ATP-dependent protein-RNA complex displacement activity term tracker item “https://github.com/geneontology/go-ontology/issues/32232”^^anyURI

• ATP-dependent protein-RNA complex displacement activity created by “ai4c-agent”

• ATP-dependent protein-RNA complex displacement activity creation date “2026-08-07T16:59:22Z”

• ATP-dependent protein-RNA complex displacement activity has_broad_synonym “RNP remodeling ATPase activity”

• ATP-dependent protein-RNA complex displacement activity has exact synonym “ATP-dependent RNA-protein complex displacement activity”

• ATP-dependent protein-RNA complex displacement activity has exact synonym “RNPase activity”

• ATP-dependent protein-RNA complex displacement activity has_obo_namespace “molecular_function”

• ATP-dependent protein-RNA complex displacement activity id “GO:7770106”

• ATP-dependent protein-RNA complex displacement activity definition “An activity that displaces a protein or protein complex from RNA in a ribonucleoprotein (RNP) complex, driven by ATP hydrolysis.”

  • database_cross_reference “PMID:28864812”

  • database_cross_reference “PMID:11175897”

  • database_cross_reference “PMID:39122693”

  • database_cross_reference “PMID:15118161”

• ATP-dependent protein-RNA complex displacement activity comment “Analogous to the DNA-side activity GO:0061995 (ATP-dependent protein-DNA complex displacement activity). The community-used term "RNPase" refers to this activity.”

• ATP-dependent protein-RNA complex displacement activity label “ATP-dependent protein-RNA complex displacement activity”

• ATP-dependent protein-RNA complex displacement activity SubClassOf ATP-dependent activity, acting on RNA

D-sorbitol biosynthetic process http://purl.obolibrary.org/obo/GO_0006061

Added

• D-sorbitol biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/32269”^^anyURI

• D-sorbitol biosynthetic process never in taxon Schizosaccharomyces

• D-sorbitol biosynthetic process SubClassOf not (in taxon some Schizosaccharomyces)

D-xylose reductase (NADPH) activity http://purl.obolibrary.org/obo/GO_0032866

Added

• D-xylose reductase (NADPH) activity term tracker item “https://github.com/geneontology/go-ontology/issues/27881”^^anyURI

• D-xylose reductase (NADPH) activity SubClassOf alcohol dehydrogenase (NADP+) activity

ER lumen protein retrieval receptor activity http://purl.obolibrary.org/obo/GO_0046923

Removed

• ER lumen protein retrieval receptor activity has exact synonym “endoplasmic reticulum retention sequence binding”

• ER lumen protein retrieval receptor activity has narrow synonym “DDEL signal sequence receptor activity”

• ER lumen protein retrieval receptor activity has narrow synonym “ER retention sequence binding”

• ER lumen protein retrieval receptor activity has narrow synonym “HDEL signal sequence receptor activity”

• ER lumen protein retrieval receptor activity has narrow synonym “KDEL signal sequence receptor activity”

• ER lumen protein retrieval receptor activity definition “Binding to an endoplasmic reticulum (ER) retention sequence, a short stretch of amino acids found in a protein that acts as a signal to retain the protein within the ER.”
  • database_cross_reference “GOC:ai”
• ER lumen protein retrieval receptor activity SubClassOf signal sequence receptor activity

Added

• ER lumen protein retrieval receptor activity term tracker item “https://github.com/geneontology/go-ontology/issues/32307”^^anyURI

• ER lumen protein retrieval receptor activity has_related_synonym “DDEL signal sequence receptor activity”

• ER lumen protein retrieval receptor activity has_related_synonym “ER retention sequence binding”

• ER lumen protein retrieval receptor activity has_related_synonym “HDEL signal sequence receptor activity”

• ER lumen protein retrieval receptor activity has_related_synonym “KDEL signal sequence receptor activity”

• ER lumen protein retrieval receptor activity has_related_synonym “endoplasmic reticulum retention sequence binding”

• ER lumen protein retrieval receptor activity definition “Binding to a C-terminal ER retrieval signal, such as KDEL, HDEL or DDEL, present on soluble lumenal proteins that have escaped from the endoplasmic reticulum (ER) to the Golgi, and mediating their return to the ER.”
  • database_cross_reference “PMID:33037041”

• ER lumen protein retrieval receptor activity SubClassOf cargo receptor activity

• ER lumen protein retrieval receptor activity SubClassOf part of some retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

ER membrane protein retrieval receptor activity http://purl.obolibrary.org/obo/GO_7770094

Added

• Class: ER membrane protein retrieval receptor activity

• ER membrane protein retrieval receptor activity term tracker item “https://github.com/geneontology/go-ontology/issues/32307”^^anyURI

• ER membrane protein retrieval receptor activity created by “ai4c-agent”

• ER membrane protein retrieval receptor activity creation date “2026-07-29T19:05:05Z”

• ER membrane protein retrieval receptor activity has exact synonym “endoplasmic reticulum membrane protein retrieval receptor activity”

• ER membrane protein retrieval receptor activity has narrow synonym “KKXX motif binding”

• ER membrane protein retrieval receptor activity has narrow synonym “KKXX signal receptor activity”

• ER membrane protein retrieval receptor activity has narrow synonym “dilysine motif binding”

• ER membrane protein retrieval receptor activity has_obo_namespace “molecular_function”

• ER membrane protein retrieval receptor activity id “GO:7770094”

• ER membrane protein retrieval receptor activity definition “Binding to a retrieval signal, such as a C-terminal KKXX/KXKX-type dilysine motif or an exposed transmembrane domain determinant, present on integral membrane proteins that have escaped from the endoplasmic reticulum (ER) to the Golgi, and mediating their return to the ER.”
  • database_cross_reference “PMID:12972550”

• ER membrane protein retrieval receptor activity label “ER membrane protein retrieval receptor activity”

• ER membrane protein retrieval receptor activity SubClassOf cargo receptor activity

• ER membrane protein retrieval receptor activity SubClassOf part of some retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

FAD regeneration via ETF:ETFQO system http://purl.obolibrary.org/obo/GO_7770096

Added

• Class: FAD regeneration via ETF:ETFQO system

• FAD regeneration via ETF:ETFQO system term tracker item “https://github.com/geneontology/go-ontology/issues/32355”^^anyURI

• FAD regeneration via ETF:ETFQO system created by “ai4c-agent”

• FAD regeneration via ETF:ETFQO system creation date “2026-07-30T22:03:00Z”

• FAD regeneration via ETF:ETFQO system has exact synonym “ETF-ETFQO system”

• FAD regeneration via ETF:ETFQO system has exact synonym “FAD regeneration via ETF-ETFQO system”

• FAD regeneration via ETF:ETFQO system has exact synonym “reoxidation of reduced electron transfer flavoprotein”

• FAD regeneration via ETF:ETFQO system has_obo_namespace “biological_process”

• FAD regeneration via ETF:ETFQO system id “GO:7770096”

• FAD regeneration via ETF:ETFQO system definition “A metabolic process that transfers electrons produced by FAD-dependent dehydrogenases involved in amino acid and lipid catabolism to the electron transport chain. Electrons released during FADH2 oxidation are transferred by electron-transfer flavoprotein (ETF) to ETF-ubiquinone oxidoreductase (ETF-QO), which in turn transfers them to ubiquinone and then to complex III of the electron transport chain.”

  • database_cross_reference “PMID:28808132”

  • database_cross_reference “PMID:33450351”

• FAD regeneration via ETF:ETFQO system comment “In eukaryotes, FAD regeneration via the ETF:ETFQO system occurs in the mitochondrion, with ETF in the matrix and ETF-QO in the inner membrane. Some bacteria and archaea have a similar system, so no taxon constraint applies to this term. This term covers the ETF/ETF-QO route specifically; do not use it for flavoprotein dehydrogenases that reduce the quinone pool directly without ETF (for example succinate dehydrogenase, see GO:0006121), or for reoxidation of flavin by molecular oxygen in peroxisomes or the endoplasmic reticulum.”

• FAD regeneration via ETF:ETFQO system label “FAD regeneration via ETF:ETFQO system”

• FAD regeneration via ETF:ETFQO system SubClassOf respiratory electron transport chain

• FAD regeneration via ETF:ETFQO system SubClassOf FAD metabolic process

• FAD regeneration via ETF:ETFQO system SubClassOf has primary output some FAD(3-)

• FAD regeneration via ETF:ETFQO system SubClassOf has primary input some FADH2(2-)

FMN adenylyltransferase activity http://purl.obolibrary.org/obo/GO_0003919

Removed

• FMN adenylyltransferase activity definition “Catalysis of the reaction: ATP + FMN = diphosphate + FAD.”

  • database_cross_reference “EC:2.7.7.2”

  • database_cross_reference “RHEA:17237”

Added

• FMN adenylyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32345”^^anyURI

• FMN adenylyltransferase activity definition “Catalysis of the reaction: FMN + ATP + H+ = FAD + diphosphate.”

  • database_cross_reference “RHEA:17237”

L-arabinose reductase (NADPH) activity http://purl.obolibrary.org/obo/GO_0032867

Added

• L-arabinose reductase (NADPH) activity term tracker item “https://github.com/geneontology/go-ontology/issues/27881”^^anyURI

• L-arabinose reductase (NADPH) activity SubClassOf alcohol dehydrogenase (NADP+) activity

L-methionine cycle http://purl.obolibrary.org/obo/GO_0033353

Removed

• L-methionine cycle definition “A cyclic series of interconversions involving S-adenosyl-L-homocysteine, L-homocysteine, L-methionine and S-adenosyl-L-methionine (SAM). Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of L-methionine.”

  • database_cross_reference “PMID:31950558”

  • database_cross_reference “PMID:39394448”

Added

• L-methionine cycle term tracker item “https://github.com/geneontology/go-ontology/issues/32362”^^anyURI

• L-methionine cycle definition “A cyclic series of interconversions involving S-adenosyl-L-homocysteine, L-homocysteine, L-methionine and S-adenosyl-L-methionine (SAM). Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of L-methionine.”

  • database_cross_reference “PMID:32961717”

  • database_cross_reference “PMID:31950558”

  • database_cross_reference “PMID:39394448”

• L-methionine cycle SubClassOf one-carbon metabolic process

NAD+ nucleosidase activity, cyclic ADP-ribose generating http://purl.obolibrary.org/obo/GO_0061809

Removed

• NAD+ nucleosidase activity, cyclic ADP-ribose generating database_cross_reference “RHEA:38615”

• NAD+ nucleosidase activity, cyclic ADP-ribose generating narrowMatch 38615

Added

• NAD+ nucleosidase activity, cyclic ADP-ribose generating term tracker item “https://github.com/geneontology/go-ontology/issues/32457”^^anyURI

• NAD+ nucleosidase activity, cyclic ADP-ribose generating SubClassOf has part some cyclic ADP-ribose hydrolase activity

NADH-dependent peroxiredoxin activity http://purl.obolibrary.org/obo/GO_0102039

Removed

• NADH-dependent peroxiredoxin activity SubClassOf peroxiredoxin activity

Added

• NADH-dependent peroxiredoxin activity term tracker item “https://github.com/geneontology/go-ontology/issues/32372”^^anyURI

• NADH-dependent peroxiredoxin activity SubClassOf peroxidase activity

NADP+ biosynthetic process http://purl.obolibrary.org/obo/GO_0006741

Removed

• NADP+ biosynthetic process conformsTo biosynthetic_process.yaml

P-type cadmium transporter activity http://purl.obolibrary.org/obo/GO_0008551

Removed

• P-type cadmium transporter activity database_cross_reference “RHEA:12132”

• P-type cadmium transporter activity exactMatch 12132

Added

• P-type cadmium transporter activity term tracker item “https://github.com/geneontology/go-ontology/issues/20824”^^anyURI

• P-type cadmium transporter activity broadMatch 12132

• P-type cadmium transporter activity comment “Note that RHEA:12132 represents both the ABC and the P-type cadmium transporters.”

RADAR pathway http://purl.obolibrary.org/obo/GO_0170074

Added

• RADAR pathway SubClassOf peroxisomal protein quality control

RNA (adenine-N6)-methyltransferase activity http://purl.obolibrary.org/obo/GO_7770107

Added

• Class: RNA (adenine-N6)-methyltransferase activity

• RNA (adenine-N6)-methyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/27200”^^anyURI

• RNA (adenine-N6)-methyltransferase activity created by “ai4c-agent”

• RNA (adenine-N6)-methyltransferase activity creation date “2026-08-07T23:44:01Z”

• RNA (adenine-N6)-methyltransferase activity has exact synonym “RNA (N6-adenosine)-methyltransferase activity”

• RNA (adenine-N6)-methyltransferase activity has exact synonym “RNA m6A methyltransferase activity”

• RNA (adenine-N6)-methyltransferase activity has_obo_namespace “molecular_function”

• RNA (adenine-N6)-methyltransferase activity id “GO:7770107”

• RNA (adenine-N6)-methyltransferase activity definition “Catalysis of the reaction: an adenosine in RNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in RNA + S-adenosyl-L-homocysteine + H+.”

  • database_cross_reference “PMID:34023900”

  • database_cross_reference “PMID:36736310”

• RNA (adenine-N6)-methyltransferase activity label “RNA (adenine-N6)-methyltransferase activity”

• RNA (adenine-N6)-methyltransferase activity SubClassOf N-methyltransferase activity

• RNA (adenine-N6)-methyltransferase activity SubClassOf RNA methyltransferase activity

S-methylmethionine cycle http://purl.obolibrary.org/obo/GO_0033528

Removed

• S-methylmethionine cycle definition “A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level.”

  • database_cross_reference “MetaCyc:PWY-5441”

  • database_cross_reference “GOC:mah”

Added

• S-methylmethionine cycle term tracker item “https://github.com/geneontology/go-ontology/issues/32362”^^anyURI

• S-methylmethionine cycle definition “A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of S-adenosylmethionine back to free L-methionine, and may serve regulate the cellular adenosylmethionine level.”

  • database_cross_reference “MetaCyc:PWY-5441”

  • database_cross_reference “GOC:mah”

  • database_cross_reference “PMID:11337394”

• S-methylmethionine cycle SubClassOf one-carbon metabolic process

• S-methylmethionine cycle SubClassOf in taxon some Viridiplantae

Sca1 Ras guanyl-nucleotide exchange factor complex http://purl.obolibrary.org/obo/GO_0170078

Added

• Class: Sca1 Ras guanyl-nucleotide exchange factor complex

• Sca1 Ras guanyl-nucleotide exchange factor complex term tracker item “https://github.com/geneontology/go-ontology/issues/32432”^^anyURI

• Sca1 Ras guanyl-nucleotide exchange factor complex created by “ew”

• Sca1 Ras guanyl-nucleotide exchange factor complex creation date “2026-08-11T17:42:26Z”

• Sca1 Ras guanyl-nucleotide exchange factor complex has_broad_synonym “Sca1 RasGEF complex”

• Sca1 Ras guanyl-nucleotide exchange factor complex has_broad_synonym “Sca1 signaling complex”

• Sca1 Ras guanyl-nucleotide exchange factor complex has_broad_synonym “Sca1-Aimless signaling complex”

• Sca1 Ras guanyl-nucleotide exchange factor complex has_broad_synonym “Sca1-associated Ras guanyl-nucleotide exchange factor complex”

• Sca1 Ras guanyl-nucleotide exchange factor complex has_obo_namespace “cellular_component”

• Sca1 Ras guanyl-nucleotide exchange factor complex id “GO:0170078”

• Sca1 Ras guanyl-nucleotide exchange factor complex definition “A protein complex found in Dictyostelium, containing the scaffold protein Sca1, the Ras guanine nucleotide exchange factors Aimless (RasGEFA) and RasGEFH, and PP2A components, which promotes RasC activation during chemotaxis.”
  • database_cross_reference “PMID:20493808”

• Sca1 Ras guanyl-nucleotide exchange factor complex label “Sca1 Ras guanyl-nucleotide exchange factor complex”

• Sca1 Ras guanyl-nucleotide exchange factor complex SubClassOf Ras guanyl-nucleotide exchange factor complex

• Sca1 Ras guanyl-nucleotide exchange factor complex SubClassOf in taxon some Dictyostelia

Sec body http://purl.obolibrary.org/obo/GO_7770092

Added

• Class: Sec body

• Sec body term tracker item “https://github.com/geneontology/go-ontology/issues/32313”^^anyURI

• Sec body created by “ai4c-agent”

• Sec body creation date “2026-07-28T23:40:49Z”

• Sec body has exact synonym “sec-body”

• Sec body has_obo_namespace “cellular_component”

• Sec body id “GO:7770092”

• Sec body definition “A condensate that forms reversibly in the cytoplasm under stress, notably amino acid starvation or salt stress, by coalescence of endoplasmic reticulum exit site (ERES) components including the scaffold protein Sec16 and COPII coat subunits. Sec bodies form through liquid-liquid phase separation and act as a protective reservoir for ERES components, permitting reversible shutdown of the early secretory pathway and promoting cell survival during stress.”

  • database_cross_reference “PMID:25386913”

  • database_cross_reference “PMID:36325988”

  • database_cross_reference “PMID:31152627”

• Sec body comment “A Sec body forms from components of an endoplasmic reticulum exit site (GO:0070971), which is progressively depleted as the Sec body grows; a Sec body is a distinct structure and is not part of an ER exit site.”

• Sec body label “Sec body”

• Sec body SubClassOf intracellular membraneless organelle

• Sec body SubClassOf part of some cytoplasm

• Sec body SubClassOf in taxon some cellular organisms

Sec body assembly http://purl.obolibrary.org/obo/GO_7770093

Added

• Class: Sec body assembly

• Sec body assembly term tracker item “https://github.com/geneontology/go-ontology/issues/32314”^^anyURI

• Sec body assembly conformsTo cc_assembly.yaml

• Sec body assembly created by “ai4c-agent”

• Sec body assembly creation date “2026-07-28T23:40:49Z”

• Sec body assembly has exact synonym “Sec body formation”

• Sec body assembly has exact synonym “sec-body assembly”

• Sec body assembly has_obo_namespace “biological_process”

• Sec body assembly id “GO:7770093”

• Sec body assembly definition “The aggregation, arrangement and bonding together of a set of components to form a Sec body.”

  • database_cross_reference “PMID:25386913”

  • database_cross_reference “PMID:27874829”

• Sec body assembly label “Sec body assembly”

• Sec body assembly EquivalentTo cellular component assembly and (results in assembly of some Sec body)

• Sec body assembly SubClassOf membraneless organelle assembly

• Sec body assembly SubClassOf in taxon some cellular organisms

• Sec body assembly SubClassOf results in assembly of some Sec body

Tim8-Tim13 complex http://purl.obolibrary.org/obo/GO_7770104

Added

• Class: Tim8-Tim13 complex

• Tim8-Tim13 complex term tracker item “https://github.com/geneontology/go-ontology/issues/32408”^^anyURI

• Tim8-Tim13 complex created by “ai4c-agent”

• Tim8-Tim13 complex creation date “2026-08-07T16:51:54Z”

• Tim8-Tim13 complex has exact synonym “TIM8-13 complex”

• Tim8-Tim13 complex has_obo_namespace “cellular_component”

• Tim8-Tim13 complex id “GO:7770104”

• Tim8-Tim13 complex definition “A chaperone complex located in the mitochondrial intermembrane space, composed of the small TIM proteins Tim8 and Tim13.”

  • database_cross_reference “PMID:33355130”

  • database_cross_reference “PMID:11101512”

• Tim8-Tim13 complex label “Tim8-Tim13 complex”

• Tim8-Tim13 complex SubClassOf mitochondrial intermembrane space chaperone complex

• Tim8-Tim13 complex SubClassOf in taxon some Eukaryota

Tim9-Tim10 complex http://purl.obolibrary.org/obo/GO_7770105

Added

• Class: Tim9-Tim10 complex

• Tim9-Tim10 complex term tracker item “https://github.com/geneontology/go-ontology/issues/32408”^^anyURI

• Tim9-Tim10 complex created by “ai4c-agent”

• Tim9-Tim10 complex creation date “2026-08-07T16:51:54Z”

• Tim9-Tim10 complex has exact synonym “TIM9-10 complex”

• Tim9-Tim10 complex has_obo_namespace “cellular_component”

• Tim9-Tim10 complex id “GO:7770105”

• Tim9-Tim10 complex definition “A chaperone complex located in the mitochondrial intermembrane space, composed of the small TIM proteins Tim9 and Tim10.”

  • database_cross_reference “PMID:16387659”

  • database_cross_reference “PMID:33355130”

• Tim9-Tim10 complex label “Tim9-Tim10 complex”

• Tim9-Tim10 complex SubClassOf mitochondrial intermembrane space chaperone complex

• Tim9-Tim10 complex SubClassOf in taxon some Eukaryota

U2 snRNA (adenine-N6)-methyltransferase activity http://purl.obolibrary.org/obo/GO_0106348

Added

• U2 snRNA (adenine-N6)-methyltransferase activity SubClassOf RNA (adenine-N6)-methyltransferase activity

U6 snRNA (adenine(43)-N6)-methyltransferase activity http://purl.obolibrary.org/obo/GO_0120048

Added

• U6 snRNA (adenine(43)-N6)-methyltransferase activity SubClassOf RNA (adenine-N6)-methyltransferase activity

alcohol dehydrogenase (NAD+) activity http://purl.obolibrary.org/obo/GO_0004022

Removed

• alcohol dehydrogenase (NAD+) activity database_cross_reference “RHEA:12785”

• alcohol dehydrogenase (NAD+) activity narrowMatch 12785

aldose reductase [NAD(P)H] activity http://purl.obolibrary.org/obo/GO_0004032

Removed

• aldose reductase [NAD(P)H] activity has exact synonym “alditol:NADP+ 1-oxidoreductase activity”

• aldose reductase [NAD(P)H] activity broadMatch ALDEHYDE-REDUCTASE-RXN

• aldose reductase [NAD(P)H] activity broadMatch 1.1.1.21

• aldose reductase [NAD(P)H] activity exactMatch 12789

• aldose reductase [NAD(P)H] activity exactMatch R02820

• aldose reductase [NAD(P)H] activity definition “Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.”
  • database_cross_reference “EC:1.1.1.21”
• aldose reductase [NAD(P)H] activity has_related_synonym “aldose reductase activity”
  • database_cross_reference “EC:1.1.1.21”

• aldose reductase [NAD(P)H] activity label “aldose reductase (NADPH) activity”

• aldose reductase [NAD(P)H] activity SubClassOf alcohol dehydrogenase (NADP+) activity

Added

• aldose reductase [NAD(P)H] activity database_cross_reference “EC:1.1.1.21”

• aldose reductase [NAD(P)H] activity database_cross_reference “MetaCyc:ALDEHYDE-REDUCTASE-RXN”

• aldose reductase [NAD(P)H] activity database_cross_reference “RHEA:12785”

• aldose reductase [NAD(P)H] activity has narrow synonym “alditol:NADP+ 1-oxidoreductase activity”

• aldose reductase [NAD(P)H] activity has narrow synonym “aldose reductase (NADPH) activity”

• aldose reductase [NAD(P)H] activity exactMatch ALDEHYDE-REDUCTASE-RXN

• aldose reductase [NAD(P)H] activity exactMatch 1.1.1.21

• aldose reductase [NAD(P)H] activity narrowMatch 12785

• aldose reductase [NAD(P)H] activity narrowMatch 12789

• aldose reductase [NAD(P)H] activity narrowMatch R02820

• aldose reductase [NAD(P)H] activity definition “Catalysis of the reaction: an alditol + NAD(P)+ = an aldose + NAD(P)H + H+.”
  • database_cross_reference “EC:1.1.1.21”
• aldose reductase [NAD(P)H] activity has exact synonym “alditol:NAD(P)+ 1-oxidoreductase activity”
  • database_cross_reference “EC:1.1.1.21”
• aldose reductase [NAD(P)H] activity has exact synonym “aldose reductase activity”
  • database_cross_reference “EC:1.1.1.21”

• aldose reductase [NAD(P)H] activity label “aldose reductase [NAD(P)H] activity”

• aldose reductase [NAD(P)H] activity SubClassOf alcohol dehydrogenase [NAD(P)+] activity

ammonia assimilation cycle http://purl.obolibrary.org/obo/GO_0019676

Added

• ammonia assimilation cycle term tracker item “https://github.com/geneontology/go-ontology/issues/32376”^^anyURI

• ammonia assimilation cycle SubClassOf nutrient assimilation

anatomical entity http://purl.obolibrary.org/obo/UBERON_0001062

Added

• anatomical entity definition “Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.”

antennal development http://purl.obolibrary.org/obo/GO_0007469

Removed

• antennal development definition “The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.”
  • database_cross_reference “http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004526”

Added

• antennal development term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• antennal development definition “The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.”

  • database_cross_reference “FBbt:00004511”

anterior compartment pattern formation http://purl.obolibrary.org/obo/GO_0007387

Removed

• anterior compartment pattern formation definition “The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• anterior compartment pattern formation term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• anterior compartment pattern formation definition “The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo.”

  • database_cross_reference “ISBN:0879694238”

anterior region determination http://purl.obolibrary.org/obo/GO_0007355

Removed

• anterior region determination definition “Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• anterior region determination term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• anterior region determination definition “Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product.”

  • database_cross_reference “ISBN:0879694238”

anterior/posterior axis specification, embryo http://purl.obolibrary.org/obo/GO_0008595

Removed

• anterior/posterior axis specification, embryo definition “The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• anterior/posterior axis specification, embryo definition “The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.”
  • database_cross_reference “ISBN:0879694238”

autophagy cargo adaptor activity http://purl.obolibrary.org/obo/GO_0160247

Removed

• autophagy cargo adaptor activity SubClassOf part of some obsolete substrate localization to autophagosome

Added

• autophagy cargo adaptor activity SubClassOf part of some macroautophagy

binding http://purl.obolibrary.org/obo/GO_0005488

Added

• binding term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI

• binding in_subset gocheck_do_not_annotate

biological_process http://purl.obolibrary.org/obo/GO_0008150

Added

• biological_process definition “A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.”

bipolar cell growth http://purl.obolibrary.org/obo/GO_0042815

Removed

• bipolar cell growth comment “Bipolar cell growth refers to a change in both cell size and cell shape. For shape changes where cell size is not affected, consider instead the term ‘establishment or maintenance of bipolar cell polarity resulting in cell shape ; GO:0061246’ and its children.”

Added

• bipolar cell growth comment “Bipolar cell growth refers to a change in both cell size and cell shape. For shape changes where cell size is not affected, consider instead the term ‘establishment or maintenance of bipolar cell polarity; GO:0061245’ and its children.”

blastoderm segmentation http://purl.obolibrary.org/obo/GO_0007350

Removed

• blastoderm segmentation definition “The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• blastoderm segmentation term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• blastoderm segmentation definition “The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.”

  • database_cross_reference “ISBN:0879694238”

carboxylic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046394

Added

• carboxylic acid biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI

• carboxylic acid biosynthetic process in_subset gocheck_do_not_annotate

carboxylic acid catabolic process http://purl.obolibrary.org/obo/GO_0046395

Added

• carboxylic acid catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI

• carboxylic acid catabolic process in_subset gocheck_do_not_annotate

cell http://purl.obolibrary.org/obo/CL_0000000

Added

• cell definition “A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.”

cell-cell junction disassembly http://purl.obolibrary.org/obo/GO_0150147

Added

• cell-cell junction disassembly never in taxon Fungi

• cell-cell junction disassembly SubClassOf not (in taxon some Fungi)

cell-cell junction maintenance http://purl.obolibrary.org/obo/GO_0045217

Added

• cell-cell junction maintenance never in taxon Fungi

• cell-cell junction maintenance SubClassOf not (in taxon some Fungi)

cell-cell junction organization http://purl.obolibrary.org/obo/GO_0045216

Added

• cell-cell junction organization never in taxon Fungi

• cell-cell junction organization SubClassOf not (in taxon some Fungi)

cellular response to interleukin-5 http://purl.obolibrary.org/obo/GO_7770103

Added

• Class: cellular response to interleukin-5

• cellular response to interleukin-5 term tracker item “https://github.com/geneontology/go-ontology/issues/32411”^^anyURI

• cellular response to interleukin-5 created by “ai4c-agent”

• cellular response to interleukin-5 creation date “2026-08-04T23:16:15Z”

• cellular response to interleukin-5 has exact synonym “cellular response to IL-5”

• cellular response to interleukin-5 has_obo_namespace “biological_process”

• cellular response to interleukin-5 id “GO:7770103”

• cellular response to interleukin-5 definition “Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-5 stimulus.”
  • database_cross_reference “PMID:41207640”

• cellular response to interleukin-5 label “cellular response to interleukin-5”

• cellular response to interleukin-5 SubClassOf cellular response to cytokine stimulus

• cellular response to interleukin-5 SubClassOf response to interleukin-5

cellular_component http://purl.obolibrary.org/obo/GO_0005575

Added

• cellular_component definition “A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).”

chitin-based cuticle development http://purl.obolibrary.org/obo/GO_0040003

Removed

• chitin-based cuticle development conformsTo anatomical_structure_development.yaml

chorion-containing eggshell formation http://purl.obolibrary.org/obo/GO_0007304

Removed

• chorion-containing eggshell formation conformsTo anatomical_structure_formation.yaml

citrate-malate shuttle http://purl.obolibrary.org/obo/GO_7770108

Added

• Class: citrate-malate shuttle

• citrate-malate shuttle term tracker item “https://github.com/geneontology/go-ontology/issues/32353”^^anyURI

• citrate-malate shuttle created by “ai4c-agent”

• citrate-malate shuttle creation date “2026-08-12T10:08:31Z”

• citrate-malate shuttle database_cross_reference “Wikipedia:Citrate-malate_shuttle”

• citrate-malate shuttle has exact synonym “citrate-malate cycle”

• citrate-malate shuttle has exact synonym “malate-citrate shuttle”

• citrate-malate shuttle has narrow synonym “acetyl-CoA biosynthesis from citrate”

• citrate-malate shuttle has_obo_namespace “biological_process”

• citrate-malate shuttle has_related_synonym “non-canonical TCA cycle”

• citrate-malate shuttle id “GO:7770108”

• citrate-malate shuttle definition “The process of transferring acetyl-CoA from the mitochondrion to the cytosol via citrate. Acetyl-CoA and oxaloacetate produced in the mitochondrion are condensed to citrate by citrate synthase; the citrate is exported to the cytosol by the mitochondrial citrate/malate antiporter in exchange for malate; in the cytosol, ATP citrate lyase cleaves the citrate back to acetyl-CoA and oxaloacetate; the oxaloacetate is then reduced to malate by cytosolic malate dehydrogenase, and the malate is imported back into the mitochondrion to complete the cycle.”

  • database_cross_reference “PMID:32414018”

  • database_cross_reference “PMID:35264789”

• citrate-malate shuttle label “citrate-malate shuttle”

• citrate-malate shuttle EquivalentTo metabolic process and (has part some ATP citrate synthase activity) and (has part some L-malate dehydrogenase (NAD+) activity)

• citrate-malate shuttle SubClassOf acetyl-CoA metabolic process

• citrate-malate shuttle SubClassOf citrate metabolic process

• citrate-malate shuttle SubClassOf has part some ATP citrate synthase activity

• citrate-malate shuttle SubClassOf has part some mitochondrial citrate transmembrane transport

• citrate-malate shuttle SubClassOf has part some L-malate dehydrogenase (NAD+) activity

• citrate-malate shuttle SubClassOf has primary output some acetyl-CoA(4-)

• citrate-malate shuttle SubClassOf has primary input some citrate(3-)

collagen and cuticulin-based cuticle development http://purl.obolibrary.org/obo/GO_0040002

Removed

• collagen and cuticulin-based cuticle development conformsTo anatomical_structure_development.yaml

compartment pattern specification http://purl.obolibrary.org/obo/GO_0007386

Removed

• compartment pattern specification definition “The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• compartment pattern specification term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• compartment pattern specification definition “The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation.”

  • database_cross_reference “ISBN:0879694238”

creatine biosynthetic process http://purl.obolibrary.org/obo/GO_0006601

Added

• creatine biosynthetic process never in taxon Archaea

• creatine biosynthetic process never in taxon Viridiplantae

• creatine biosynthetic process never in taxon Schizosaccharomyces pombe

• creatine biosynthetic process never in taxon Insecta

• creatine biosynthetic process SubClassOf not (in taxon some Archaea)

• creatine biosynthetic process SubClassOf not (in taxon some Viridiplantae)

• creatine biosynthetic process SubClassOf not (in taxon some Schizosaccharomyces pombe)

• creatine biosynthetic process SubClassOf not (in taxon some Insecta)

creatine metabolic process http://purl.obolibrary.org/obo/GO_0006600

Added

• creatine metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32279”^^anyURI

• creatine metabolic process never in taxon Archaea

• creatine metabolic process never in taxon Viridiplantae

• creatine metabolic process never in taxon Schizosaccharomyces pombe

• creatine metabolic process never in taxon Insecta

• creatine metabolic process SubClassOf not (in taxon some Archaea)

• creatine metabolic process SubClassOf not (in taxon some Viridiplantae)

• creatine metabolic process SubClassOf not (in taxon some Schizosaccharomyces pombe)

• creatine metabolic process SubClassOf not (in taxon some Insecta)

cuticle development http://purl.obolibrary.org/obo/GO_0042335

Removed

• cuticle development conformsTo anatomical_structure_development.yaml

cyclic ADP-ribose hydrolase activity http://purl.obolibrary.org/obo/GO_0061812

Removed

• cyclic ADP-ribose hydrolase activity term replaced by NAD+ nucleosidase activity, cyclic ADP-ribose generating

• cyclic ADP-ribose hydrolase activity definition “OBSOLETE. Catalysis of the reaction: cyclic ADP-ribose + H20 = ADP-ribose (ADPR).”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “PMID:11866528”

  • database_cross_reference “GOC:PARL”

  • database_cross_reference “GOC:pad”

• cyclic ADP-ribose hydrolase activity deprecated true

• cyclic ADP-ribose hydrolase activity comment “This term was obsoleted because it represents a step in a multi-step reaction.”

• cyclic ADP-ribose hydrolase activity label “obsolete cyclic ADP-ribose hydrolase”

Added

• cyclic ADP-ribose hydrolase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32457”^^anyURI

• cyclic ADP-ribose hydrolase activity database_cross_reference “RHEA:38615”

• cyclic ADP-ribose hydrolase activity has exact synonym “cADPR hydrolase activity”

• cyclic ADP-ribose hydrolase activity exactMatch 38615

• cyclic ADP-ribose hydrolase activity definition “Catalysis of the reaction: cyclic ADP-beta-D-ribose + H2O = ADP-D-ribose.”

  • database_cross_reference “PMID:42243876”

  • database_cross_reference “RHEA:38615”

• cyclic ADP-ribose hydrolase activity comment “Note that this term was reinstated from obsolete.”

• cyclic ADP-ribose hydrolase activity label “cyclic ADP-ribose hydrolase activity”

• cyclic ADP-ribose hydrolase activity SubClassOf hydrolase activity, hydrolyzing N-glycosyl compounds

cytoplasm protein quality control http://purl.obolibrary.org/obo/GO_0140455

Removed

• cytoplasm protein quality control definition “The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.”
  • database_cross_reference “PMID:32075773”

Added

• cytoplasm protein quality control term tracker item “https://github.com/geneontology/go-ontology/issues/32442”^^anyURI

• cytoplasm protein quality control definition “The chemical reactions and pathways resulting in the breakdown or refolding of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.”

  • database_cross_reference “PMID:32075773”

desmosome disassembly http://purl.obolibrary.org/obo/GO_0035921

Added

• desmosome disassembly never in taxon Fungi

• desmosome disassembly SubClassOf not (in taxon some Fungi)

desmosome maintenance http://purl.obolibrary.org/obo/GO_0002160

Added

• desmosome maintenance never in taxon Fungi

• desmosome maintenance SubClassOf not (in taxon some Fungi)

desmosome organization http://purl.obolibrary.org/obo/GO_0002934

Added

• desmosome organization never in taxon Fungi

• desmosome organization SubClassOf not (in taxon some Fungi)

dissimilatory sulfate reduction http://purl.obolibrary.org/obo/GO_0019420

Removed

• dissimilatory sulfate reduction SubClassOf sulfate assimilation

Added

• dissimilatory sulfate reduction SubClassOf sulfur compound metabolic process

eggshell formation http://purl.obolibrary.org/obo/GO_0030703

Removed

• eggshell formation conformsTo anatomical_structure_formation.yaml

ent-kaurene biosynthetic process http://purl.obolibrary.org/obo/GO_0033332

Removed

• ent-kaurene biosynthetic process SubClassOf obsolete ent-kaurene metabolic process

exit from cytosolic ribosome hibernation http://purl.obolibrary.org/obo/GO_7770110

Added

• Class: exit from cytosolic ribosome hibernation

• exit from cytosolic ribosome hibernation term tracker item “https://github.com/geneontology/go-ontology/issues/32461”^^anyURI

• exit from cytosolic ribosome hibernation created by “ai4c-agent”

• exit from cytosolic ribosome hibernation creation date “2026-08-14T22:52:06Z”

• exit from cytosolic ribosome hibernation has exact synonym “ribosome hibernation exit”

• exit from cytosolic ribosome hibernation has exact synonym “translational restart after ribosome hibernation”

• exit from cytosolic ribosome hibernation has_obo_namespace “biological_process”

• exit from cytosolic ribosome hibernation has_related_synonym “ribosome reactivation”

• exit from cytosolic ribosome hibernation id “GO:7770110”

• exit from cytosolic ribosome hibernation definition “A cellular process that results in the reactivation of hibernating cytosolic ribosomes, enabling them to resume translation. Upon reversal of unfavorable conditions such as nutrient limitation, dedicated molecular machinery reactivates hibernating ribosomes and promotes recovery of active translation.”

  • database_cross_reference “PMID:32687489”

  • database_cross_reference “PMID:42129552”

• exit from cytosolic ribosome hibernation label “exit from cytosolic ribosome hibernation”

• exit from cytosolic ribosome hibernation SubClassOf positive regulation of cytoplasmic translation

• exit from cytosolic ribosome hibernation SubClassOf in taxon some cellular organisms

folate cycle http://purl.obolibrary.org/obo/GO_0035999

Removed

• folate cycle has exact synonym “folate cycle”

• folate cycle definition “The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesize other tetrahydrofolate molecules.”

  • database_cross_reference “GOC:yaf”

  • database_cross_reference “PMID:1825999”

• folate cycle label “tetrahydrofolate interconversion”

Added

• folate cycle term tracker item “https://github.com/geneontology/go-ontology/issues/32362”^^anyURI

• folate cycle has exact synonym “folate-mediated one-carbon metabolism”

• folate cycle has exact synonym “folic acid cycle”

• folate cycle has exact synonym “tetrahydrofolate interconversion”

• folate cycle definition “A cyclic series of interconversions of the one-carbon unit carried by tetrahydrofolate - as 10-formyltetrahydrofolate, 5,10-methenyltetrahydrofolate, 5,10-methylenetetrahydrofolate and 5-methyltetrahydrofolate. Couples the acquisition of a one-carbon unit from donors such as serine, glycine or formate with its transfer, in the appropriate oxidation state, to biosynthetic acceptors, and with regeneration of tetrahydrofolate.”

  • database_cross_reference “PMID:18804690”

  • database_cross_reference “PMID:27641100”

  • database_cross_reference “PMID:1825999”

• folate cycle label “folate cycle”

formaldehyde assimilation http://purl.obolibrary.org/obo/GO_0019649

Added

• formaldehyde assimilation SubClassOf nutrient assimilation

fructose export from vacuole to cytosol http://purl.obolibrary.org/obo/GO_1902334

Removed

• fructose export from vacuole to cytosol label “fructose export from vacuole to cytoplasm”

Added

• fructose export from vacuole to cytosol term tracker item “https://github.com/geneontology/go-ontology/issues/32419”^^anyURI

• fructose export from vacuole to cytosol label “fructose export from vacuole to cytosol”

gamma-1,2,3,4,5,6-hexachlorocyclohexane catabolic process http://purl.obolibrary.org/obo/GO_0018919

Removed

• gamma-1,2,3,4,5,6-hexachlorocyclohexane catabolic process conformsTo metabolic_process.yaml

ganglioside biosynthetic process http://purl.obolibrary.org/obo/GO_0001574

Added

• ganglioside biosynthetic process never in taxon Insecta

• ganglioside biosynthetic process SubClassOf not (in taxon some Insecta)

ganglioside catabolic process http://purl.obolibrary.org/obo/GO_0006689

Added

• ganglioside catabolic process never in taxon Insecta

• ganglioside catabolic process SubClassOf not (in taxon some Insecta)

ganglioside metabolic process http://purl.obolibrary.org/obo/GO_0001573

Added

• ganglioside metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32322”^^anyURI

• ganglioside metabolic process never in taxon Insecta

• ganglioside metabolic process SubClassOf not (in taxon some Insecta)

gap endonuclease activity http://purl.obolibrary.org/obo/GO_0170076

Added

• Class: gap endonuclease activity

• gap endonuclease activity term tracker item “https://github.com/geneontology/go-ontology/issues/32367”^^anyURI

• gap endonuclease activity created by “ew”

• gap endonuclease activity creation date “2026-08-10T17:51:18Z”

• gap endonuclease activity has exact synonym “GEN activity”

• gap endonuclease activity has exact synonym “Gap specific endonuclease activity”

• gap endonuclease activity has_obo_namespace “molecular_function”

• gap endonuclease activity id “GO:0170076”

• gap endonuclease activity definition “Specific recognition and catalysis of the internal cleavage of the phosphodiester backbone within single-stranded DNA gaps or looped DNA structures at the junctions of single-stranded and double-stranded DNA. Primarily involved in the resolution of triplet repeat sequences, removal of aberrant secondary structures formed during the maturation of Okazaki fragments, telomeric R-loop resolution and the processing of stalled replication forks, that all involve cleavage at internal or branched DNA structures.”

  • database_cross_reference “PMID:15592449”

  • database_cross_reference “PMID:10330154”

• gap endonuclease activity label “gap endonuclease activity”

• gap endonuclease activity SubClassOf DNA endonuclease activity

glomerular basement membrane development http://purl.obolibrary.org/obo/GO_0032836

Removed

• glomerular basement membrane development conformsTo anatomical_structure_development.yaml

glutaredoxin-dependent peroxiredoxin activity http://purl.obolibrary.org/obo/GO_7770099

Added

• Class: glutaredoxin-dependent peroxiredoxin activity

• glutaredoxin-dependent peroxiredoxin activity term tracker item “https://github.com/geneontology/go-ontology/issues/32405”^^anyURI

• glutaredoxin-dependent peroxiredoxin activity created by “ai4c-agent”

• glutaredoxin-dependent peroxiredoxin activity creation date “2026-08-04T17:43:33Z”

• glutaredoxin-dependent peroxiredoxin activity database_cross_reference “EC:1.11.1.25”

• glutaredoxin-dependent peroxiredoxin activity database_cross_reference “RHEA:62624”

• glutaredoxin-dependent peroxiredoxin activity has exact synonym “GrxPx activity”

• glutaredoxin-dependent peroxiredoxin activity has_obo_namespace “molecular_function”

• glutaredoxin-dependent peroxiredoxin activity has_related_synonym “thiol peroxidase activity”

• glutaredoxin-dependent peroxiredoxin activity id “GO:7770099”

• glutaredoxin-dependent peroxiredoxin activity exactMatch 1.11.1.25

• glutaredoxin-dependent peroxiredoxin activity exactMatch 62624

• glutaredoxin-dependent peroxiredoxin activity definition “Catalysis of the reaction: [glutaredoxin]-dithiol + a hydroperoxide = [glutaredoxin]-disulfide + an alcohol + H2O.”

  • database_cross_reference “RHEA:62624”

  • database_cross_reference “PMID:12517450”

  • database_cross_reference “PMID:11832487”

• glutaredoxin-dependent peroxiredoxin activity label “glutaredoxin-dependent peroxiredoxin activity”

• glutaredoxin-dependent peroxiredoxin activity SubClassOf peroxiredoxin activity

• glutaredoxin-dependent peroxiredoxin activity SubClassOf has participant some water

• glutaredoxin-dependent peroxiredoxin activity SubClassOf has participant some L-cysteine residue

• glutaredoxin-dependent peroxiredoxin activity SubClassOf has participant some alcohol

• glutaredoxin-dependent peroxiredoxin activity SubClassOf has participant some peroxol

• glutaredoxin-dependent peroxiredoxin activity SubClassOf has participant some L-cystine residue

glutathione-dependent peroxiredoxin activity http://purl.obolibrary.org/obo/GO_7770101

Added

• Class: glutathione-dependent peroxiredoxin activity

• glutathione-dependent peroxiredoxin activity term tracker item “https://github.com/geneontology/go-ontology/issues/32405”^^anyURI

• glutathione-dependent peroxiredoxin activity created by “ai4c-agent”

• glutathione-dependent peroxiredoxin activity creation date “2026-08-04T17:43:33Z”

• glutathione-dependent peroxiredoxin activity database_cross_reference “EC:1.11.1.27”

• glutathione-dependent peroxiredoxin activity database_cross_reference “RHEA:62632”

• glutathione-dependent peroxiredoxin activity database_cross_reference “RHEA:69412”

• glutathione-dependent peroxiredoxin activity database_cross_reference “RHEA:69651”

• glutathione-dependent peroxiredoxin activity database_cross_reference “RHEA:76731”

• glutathione-dependent peroxiredoxin activity has_obo_namespace “molecular_function”

• glutathione-dependent peroxiredoxin activity has_related_synonym “thiol peroxidase activity”

• glutathione-dependent peroxiredoxin activity id “GO:7770101”

• glutathione-dependent peroxiredoxin activity exactMatch 1.11.1.27

• glutathione-dependent peroxiredoxin activity exactMatch 62632

• glutathione-dependent peroxiredoxin activity narrowMatch 69412

• glutathione-dependent peroxiredoxin activity narrowMatch 69651

• glutathione-dependent peroxiredoxin activity narrowMatch 76731

• glutathione-dependent peroxiredoxin activity definition “Catalysis of the reaction: a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.”

  • database_cross_reference “RHEA:62632”

  • database_cross_reference “PMID:15004285”

  • database_cross_reference “PMID:12606554”

• glutathione-dependent peroxiredoxin activity label “glutathione-dependent peroxiredoxin activity”

• glutathione-dependent peroxiredoxin activity SubClassOf peroxidase activity

• glutathione-dependent peroxiredoxin activity SubClassOf has participant some water

• glutathione-dependent peroxiredoxin activity SubClassOf has participant some alcohol

• glutathione-dependent peroxiredoxin activity SubClassOf has participant some peroxol

• glutathione-dependent peroxiredoxin activity SubClassOf has participant some glutathionate(1-)

• glutathione-dependent peroxiredoxin activity SubClassOf has participant some glutathione disulfide(2-)

glycine decarboxylation via glycine cleavage system http://purl.obolibrary.org/obo/GO_0019464

Removed

• glycine decarboxylation via glycine cleavage system definition “The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.”
  • database_cross_reference “MetaCyc:GLYCLEAV-PWY”

Added

• glycine decarboxylation via glycine cleavage system term tracker item “https://github.com/geneontology/go-ontology/issues/32362”^^anyURI

• glycine decarboxylation via glycine cleavage system definition “The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.”

  • database_cross_reference “PMID:41521798”

  • database_cross_reference “MetaCyc:GLYCLEAV-PWY”

  • database_cross_reference “PMID:36347252”

granulocyte colony-stimulating factor receptor activity http://purl.obolibrary.org/obo/GO_0004902

Removed

• granulocyte colony-stimulating factor receptor activity never in taxon Fungi

• granulocyte colony-stimulating factor receptor activity SubClassOf not (in taxon some Fungi)

Added

• granulocyte colony-stimulating factor receptor activity SubClassOf in taxon some [Vertebrata ](http://purl.obolibrary.org/obo/NCBITaxon_7742)

granulocyte colony-stimulating factor signaling pathway http://purl.obolibrary.org/obo/GO_0038158

Added

• granulocyte colony-stimulating factor signaling pathway term tracker item “https://github.com/geneontology/go-ontology/issues/32373”^^anyURI

• granulocyte colony-stimulating factor signaling pathway SubClassOf in taxon some [Vertebrata ](http://purl.obolibrary.org/obo/NCBITaxon_7742)

group translocator activity http://purl.obolibrary.org/obo/GO_7770111

Added

• Class: group translocator activity

• group translocator activity term tracker item “https://github.com/geneontology/go-ontology/issues/27496”^^anyURI

• group translocator activity created by “ai4c-agent”

• group translocator activity creation date “2026-08-18T00:41:26Z”

• group translocator activity database_cross_reference “TC:4”

• group translocator activity has exact synonym “group translocation activity”

• group translocator activity has_obo_namespace “molecular_function”

• group translocator activity has_related_synonym “group translocator”

• group translocator activity id “GO:7770111”

• group translocator activity definition “Enables the transfer of a substance from one side of a membrane to the other, where the substance is chemically modified as an integral part of the translocation process, so that the species released on the far side of the membrane is not the species that was bound on the near side. This differs from primary and secondary active transport, in which the transported substance is unchanged.”

  • database_cross_reference “PMID:31214989”

  • database_cross_reference “PMID:33170213”

• group translocator activity label “group translocator activity”

• group translocator activity SubClassOf transmembrane transporter activity

• group translocator activity SubClassOf has part some catalytic activity

heme export from vacuole to cytosol http://purl.obolibrary.org/obo/GO_0140357

Removed

• heme export from vacuole to cytosol label “heme export from vacuole to cytoplasm”

Added

• heme export from vacuole to cytosol term tracker item “https://github.com/geneontology/go-ontology/issues/32419”^^anyURI

• heme export from vacuole to cytosol label “heme export from vacuole to cytosol”

imaginal disc-derived wing vein morphogenesis http://purl.obolibrary.org/obo/GO_0008586

Removed

• imaginal disc-derived wing vein morphogenesis conformsTo anatomical_structure_morphogenesis.yaml

immaterial anatomical entity http://purl.obolibrary.org/obo/UBERON_0000466

Added

• immaterial anatomical entity definition “Anatomical entity that has no mass.”

interleukin-5-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0038043

Added

• interleukin-5-mediated signaling pathway SubClassOf part of some cellular response to interleukin-5

intestinal enterochromaffin enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_7770020

Added

• intestinal enterochromaffin enteroendocrine cell differentiation conformsTo cell_differentiation_by_mature_cell_type.yaml

intestinal type G enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_7770021

Added

• intestinal type G enteroendocrine cell differentiation conformsTo cell_differentiation_by_mature_cell_type.yaml

intestinal type I enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_7770022

Added

• intestinal type I enteroendocrine cell differentiation conformsTo cell_differentiation_by_mature_cell_type.yaml

intestinal type L enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_7770023

Added

• intestinal type L enteroendocrine cell differentiation conformsTo cell_differentiation_by_mature_cell_type.yaml

intestinal type N enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_7770024

Added

• intestinal type N enteroendocrine cell differentiation conformsTo cell_differentiation_by_mature_cell_type.yaml

intracellular organelle lumen http://purl.obolibrary.org/obo/GO_0070013

Added

• intracellular organelle lumen term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI

• intracellular organelle lumen in_subset gocheck_do_not_annotate

inward rectifier potassium channel inhibitor activity http://purl.obolibrary.org/obo/GO_0070320

Removed

• inward rectifier potassium channel inhibitor activity SubClassOf potassium channel inhibitor activity

Added

• inward rectifier potassium channel inhibitor activity SubClassOf voltage-gated potassium channel inhibitor activity

large conductance calcium-activated potassium channel inhibitor activity http://purl.obolibrary.org/obo/GO_7770089

Added

• Class: large conductance calcium-activated potassium channel inhibitor activity

• large conductance calcium-activated potassium channel inhibitor activity term tracker item “https://github.com/geneontology/go-ontology/issues/32358”^^anyURI

• large conductance calcium-activated potassium channel inhibitor activity created by “ai4c-agent”

• large conductance calcium-activated potassium channel inhibitor activity creation date “2026-07-28T00:46:41Z”

• large conductance calcium-activated potassium channel inhibitor activity has exact synonym “BK KCa channel inhibitor activity”

• large conductance calcium-activated potassium channel inhibitor activity has exact synonym “BK calcium-activated potassium channel inhibitor activity”

• large conductance calcium-activated potassium channel inhibitor activity has exact synonym “large conductance KCa channel inhibitor activity”

• large conductance calcium-activated potassium channel inhibitor activity has_obo_namespace “molecular_function”

• large conductance calcium-activated potassium channel inhibitor activity has_related_synonym “BK channel inhibitor activity”

• large conductance calcium-activated potassium channel inhibitor activity id “GO:7770089”

• large conductance calcium-activated potassium channel inhibitor activity definition “Binds to and stops, prevents, or reduces the activity of a large conductance calcium-activated potassium channel.”

  • database_cross_reference “PMID:39971906”

  • database_cross_reference “PMID:17591990”

• large conductance calcium-activated potassium channel inhibitor activity label “large conductance calcium-activated potassium channel inhibitor activity”

• large conductance calcium-activated potassium channel inhibitor activity EquivalentTo molecular function inhibitor activity and (directly negatively regulates some large conductance calcium-activated potassium channel activity)

• large conductance calcium-activated potassium channel inhibitor activity SubClassOf potassium channel inhibitor activity

• large conductance calcium-activated potassium channel inhibitor activity SubClassOf directly negatively regulates some large conductance calcium-activated potassium channel activity

lipoyl-GcvH:protein N-lipoyltransferase activity http://purl.obolibrary.org/obo/GO_7770091

Added

• Class: lipoyl-GcvH:protein N-lipoyltransferase activity

• lipoyl-GcvH:protein N-lipoyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32361”^^anyURI

• lipoyl-GcvH:protein N-lipoyltransferase activity created by “ai4c-agent”

• lipoyl-GcvH:protein N-lipoyltransferase activity creation date “2026-07-28T20:08:06Z”

• lipoyl-GcvH:protein N-lipoyltransferase activity has_broad_synonym “lipoyl amidotransferase activity”

• lipoyl-GcvH:protein N-lipoyltransferase activity database_cross_reference “EC:2.3.1.204”

• lipoyl-GcvH:protein N-lipoyltransferase activity database_cross_reference “RHEA:16413”

• lipoyl-GcvH:protein N-lipoyltransferase activity database_cross_reference “RHEA:20213”

• lipoyl-GcvH:protein N-lipoyltransferase activity has_obo_namespace “molecular_function”

• lipoyl-GcvH:protein N-lipoyltransferase activity has_related_synonym “lipoyl relay activity”

• lipoyl-GcvH:protein N-lipoyltransferase activity has_related_synonym “octanoyl-[GcvH]:protein N-octanoyltransferase activity”

• lipoyl-GcvH:protein N-lipoyltransferase activity id “GO:7770091”

• lipoyl-GcvH:protein N-lipoyltransferase activity exactMatch 2.3.1.204

• lipoyl-GcvH:protein N-lipoyltransferase activity narrowMatch 16413

• lipoyl-GcvH:protein N-lipoyltransferase activity narrowMatch 20213

• lipoyl-GcvH:protein N-lipoyltransferase activity definition “Catalysis of the reaction: N6-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + L-lysyl-[lipoyl-carrier protein] = L-lysyl-[glycine-cleavage complex H protein] + N6-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein].”

  • database_cross_reference “PMID:38624243”

  • database_cross_reference “EC:2.3.1.204”

• lipoyl-GcvH:protein N-lipoyltransferase activity comment “The enzyme also transfers the biosynthetic precursor octanoyl group, and relays the acyl group from GcvH onto the E2 subunits of the pyruvate, 2-oxoglutarate, branched-chain 2-oxoacid and acetoin dehydrogenase complexes.”

• lipoyl-GcvH:protein N-lipoyltransferase activity label “lipoyl-GcvH:protein N-lipoyltransferase activity”

• lipoyl-GcvH:protein N-lipoyltransferase activity SubClassOf acyltransferase activity, transferring groups other than amino-acyl groups

• lipoyl-GcvH:protein N-lipoyltransferase activity SubClassOf catalytic activity, acting on a protein

mRNA m(6)A methyltransferase activity http://purl.obolibrary.org/obo/GO_0001734

Added

• mRNA m(6)A methyltransferase activity SubClassOf RNA (adenine-N6)-methyltransferase activity

material anatomical entity http://purl.obolibrary.org/obo/UBERON_0000465

Added

• material anatomical entity definition “Anatomical entity that has mass.”

maternal determination of anterior/posterior axis, embryo http://purl.obolibrary.org/obo/GO_0008358

Removed

• maternal determination of anterior/posterior axis, embryo definition “The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• maternal determination of anterior/posterior axis, embryo term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• maternal determination of anterior/posterior axis, embryo definition “The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos.”

  • database_cross_reference “ISBN:0879694238”

membrane insertase activity http://purl.obolibrary.org/obo/GO_0032977

Removed

• membrane insertase activity EquivalentTo molecular carrier activity and (part of some establishment of protein localization to membrane) and (has primary input some protein)

• membrane insertase activity SubClassOf part of some establishment of protein localization to membrane

Added

• membrane insertase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32404”^^anyURI

mitochondrial intermembrane space chaperone complex http://purl.obolibrary.org/obo/GO_0042719

Removed

• mitochondrial intermembrane space chaperone complex has narrow synonym “Tim8-Tim13 complex”

• mitochondrial intermembrane space chaperone complex has narrow synonym “Tim9-Tim10 complex”

Added

• mitochondrial intermembrane space chaperone complex term tracker item “https://github.com/geneontology/go-ontology/issues/32408”^^anyURI

mitochondrial membrane organization http://purl.obolibrary.org/obo/GO_0007006

Removed

• mitochondrial membrane organization conformsTo occursIn.yaml

• mitochondrial membrane organization EquivalentTo membrane organization and (occurs in some mitochondrion)

• mitochondrial membrane organization SubClassOf mitochondrion organization

• mitochondrial membrane organization SubClassOf occurs in some mitochondrion

Added

• mitochondrial membrane organization term tracker item “https://github.com/geneontology/go-ontology/issues/32356”^^anyURI

• mitochondrial membrane organization EquivalentTo membrane organization and (results in organization of some mitochondrial membrane)

• mitochondrial membrane organization SubClassOf part of some mitochondrion organization

• mitochondrial membrane organization SubClassOf results in organization of some mitochondrial membrane

mitochondrial protein quality control http://purl.obolibrary.org/obo/GO_0141164

Added

• mitochondrial protein quality control SubClassOf protein catabolic process

molecular_function http://purl.obolibrary.org/obo/GO_0003674

Added

• molecular_function definition “A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.”

momilactone-A synthase [NAD(P)H] activity http://purl.obolibrary.org/obo/GO_0102960

Removed

• momilactone-A synthase [NAD(P)H] activity exactMatch 25363

mycoredoxin-dependent peroxiredoxin activity http://purl.obolibrary.org/obo/GO_7770100

Added

• Class: mycoredoxin-dependent peroxiredoxin activity

• mycoredoxin-dependent peroxiredoxin activity term tracker item “https://github.com/geneontology/go-ontology/issues/32405”^^anyURI

• mycoredoxin-dependent peroxiredoxin activity created by “ai4c-agent”

• mycoredoxin-dependent peroxiredoxin activity creation date “2026-08-04T17:43:33Z”

• mycoredoxin-dependent peroxiredoxin activity database_cross_reference “EC:1.11.1.29”

• mycoredoxin-dependent peroxiredoxin activity database_cross_reference “RHEA:62640”

• mycoredoxin-dependent peroxiredoxin activity has_obo_namespace “molecular_function”

• mycoredoxin-dependent peroxiredoxin activity has_related_synonym “thiol peroxidase activity”

• mycoredoxin-dependent peroxiredoxin activity id “GO:7770100”

• mycoredoxin-dependent peroxiredoxin activity exactMatch 1.11.1.29

• mycoredoxin-dependent peroxiredoxin activity exactMatch 62640

• mycoredoxin-dependent peroxiredoxin activity definition “Catalysis of the reaction: [mycoredoxin]-dithiol + a hydroperoxide = [mycoredoxin]-disulfide + an alcohol + H2O.”

  • database_cross_reference “RHEA:62640”

  • database_cross_reference “PMID:19737009”

  • database_cross_reference “PMID:24379404”

• mycoredoxin-dependent peroxiredoxin activity label “mycoredoxin-dependent peroxiredoxin activity”

• mycoredoxin-dependent peroxiredoxin activity SubClassOf peroxiredoxin activity

• mycoredoxin-dependent peroxiredoxin activity SubClassOf has participant some water

• mycoredoxin-dependent peroxiredoxin activity SubClassOf has participant some L-cysteine residue

• mycoredoxin-dependent peroxiredoxin activity SubClassOf has participant some alcohol

• mycoredoxin-dependent peroxiredoxin activity SubClassOf has participant some peroxol

• mycoredoxin-dependent peroxiredoxin activity SubClassOf has participant some L-cystine residue

myo-inositol export across plasma membrane http://purl.obolibrary.org/obo/GO_7770109

Added

• Class: myo-inositol export across plasma membrane

• myo-inositol export across plasma membrane term tracker item “https://github.com/geneontology/go-ontology/issues/32460”^^anyURI

• myo-inositol export across plasma membrane created by “ai4c-agent”

• myo-inositol export across plasma membrane creation date “2026-08-14T19:33:20Z”

• myo-inositol export across plasma membrane has_broad_synonym “inositol export”

• myo-inositol export across plasma membrane has_broad_synonym “myo-inositol export”

• myo-inositol export across plasma membrane has exact synonym “myo-inositol export from cell”

• myo-inositol export across plasma membrane has_obo_namespace “biological_process”

• myo-inositol export across plasma membrane id “GO:7770109”

• myo-inositol export across plasma membrane definition “The directed movement of myo-inositol from inside of a cell, across the plasma membrane and into the extracellular region.”
  • database_cross_reference “PMID:42567923”

• myo-inositol export across plasma membrane label “myo-inositol export across plasma membrane”

• myo-inositol export across plasma membrane EquivalentTo transport and (has target start location some cytosol) and (has target end location some extracellular region) and (results in transport across some plasma membrane) and (has primary input some myo-inositol)

• myo-inositol export across plasma membrane SubClassOf polyol transmembrane transport

• myo-inositol export across plasma membrane SubClassOf myo-inositol transport

• myo-inositol export across plasma membrane SubClassOf export across plasma membrane

negative regulation of ‘de novo’ NAD biosynthetic process from L-tryptophan http://purl.obolibrary.org/obo/GO_1905013

Added

• negative regulation of ‘de novo’ NAD biosynthetic process from L-tryptophan never in taxon Schizosaccharomyces pombe

• negative regulation of ‘de novo’ NAD biosynthetic process from L-tryptophan SubClassOf not (in taxon some Schizosaccharomyces pombe)

negative regulation of coenzyme A biosynthetic process http://purl.obolibrary.org/obo/GO_0170077

Added

• Class: negative regulation of coenzyme A biosynthetic process

• negative regulation of coenzyme A biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/32390”^^anyURI

• negative regulation of coenzyme A biosynthetic process created by “ew”

• negative regulation of coenzyme A biosynthetic process creation date “2026-08-10T18:46:59Z”

• negative regulation of coenzyme A biosynthetic process has_obo_namespace “biological_process”

• negative regulation of coenzyme A biosynthetic process id “GO:0170077”

• negative regulation of coenzyme A biosynthetic process definition “Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of coenzyme A.”
  • database_cross_reference “PMID:42000723”

• negative regulation of coenzyme A biosynthetic process label “negative regulation of coenzyme A biosynthetic process”

• negative regulation of coenzyme A biosynthetic process SubClassOf regulation of coenzyme A biosynthetic process

negative regulation of cristae formation http://purl.obolibrary.org/obo/GO_1903851

Removed

• negative regulation of cristae formation SubClassOf negative regulation of organelle organization

Added

• negative regulation of cristae formation SubClassOf negative regulation of cellular component organization

negative regulation of tight junction disassembly http://purl.obolibrary.org/obo/GO_1905074

Added

• negative regulation of tight junction disassembly never in taxon Fungi

• negative regulation of tight junction disassembly SubClassOf not (in taxon some Fungi)

nitrate assimilation http://purl.obolibrary.org/obo/GO_0042128

Added

• nitrate assimilation term tracker item “https://github.com/geneontology/go-ontology/issues/32376”^^anyURI

• nitrate assimilation SubClassOf nutrient assimilation

nutrient assimilation http://purl.obolibrary.org/obo/GO_7770097

Added

• Class: nutrient assimilation

• nutrient assimilation term tracker item “https://github.com/geneontology/go-ontology/issues/32376”^^anyURI

• nutrient assimilation created by “ai4c-agent”

• nutrient assimilation creation date “2026-07-29T05:36:39Z”

• nutrient assimilation has exact synonym “assimilation of nutrients”

• nutrient assimilation has_obo_namespace “biological_process”

• nutrient assimilation id “GO:7770097”

• nutrient assimilation in_subset gocheck_do_not_annotate

• nutrient assimilation definition “The chemical reactions and pathways by which a cell or organism takes up a nutrient from its environment and incorporates it into cellular constituents, characteristically converting a simple, usually inorganic, nutrient source such as nitrate, sulfate, ammonia or a one-carbon compound into organic constituents of the cell.”

  • database_cross_reference “PMID:34973427”

  • database_cross_reference “PMID:22103536”

  • database_cross_reference “PMID:27572125”

• nutrient assimilation label “nutrient assimilation”

• nutrient assimilation SubClassOf metabolic process

obsolete (1->3)-alpha-glucan metabolic process http://purl.obolibrary.org/obo/GO_0070595

Removed

• obsolete (1->3)-alpha-glucan metabolic process conformsTo metabolic_process.yaml

obsolete (1->4)-alpha-glucan metabolic process http://purl.obolibrary.org/obo/GO_0070629

Removed

• obsolete (1->4)-alpha-glucan metabolic process conformsTo metabolic_process.yaml

obsolete (Z)-nonadeca-1,14-diene biosynthetic process http://purl.obolibrary.org/obo/GO_1900879

Removed

• obsolete (Z)-nonadeca-1,14-diene biosynthetic process conformsTo biosynthetic_process.yaml

obsolete (Z)-nonadeca-1,14-diene metabolic process http://purl.obolibrary.org/obo/GO_1900878

Removed

• obsolete (Z)-nonadeca-1,14-diene metabolic process conformsTo metabolic_process.yaml

obsolete 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process http://purl.obolibrary.org/obo/GO_0018977

Removed

• obsolete 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process conformsTo metabolic_process.yaml

obsolete 1,2,3-tribromopropane metabolic process http://purl.obolibrary.org/obo/GO_0018976

Removed

• obsolete 1,2,3-tribromopropane metabolic process conformsTo metabolic_process.yaml

obsolete 1,3-dichloropropene metabolic process http://purl.obolibrary.org/obo/GO_0018903

Removed

• obsolete 1,3-dichloropropene metabolic process conformsTo metabolic_process.yaml

obsolete 10-formyltetrahydrofolate biosynthetic process http://purl.obolibrary.org/obo/GO_0009257

Removed

• obsolete 10-formyltetrahydrofolate biosynthetic process conformsTo biosynthetic_process.yaml

• obsolete 10-formyltetrahydrofolate biosynthetic process definition “The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.”
  • database_cross_reference “GOC:ai”

• obsolete 10-formyltetrahydrofolate biosynthetic process label “10-formyltetrahydrofolate biosynthetic process”

• obsolete 10-formyltetrahydrofolate biosynthetic process EquivalentTo biosynthetic process and (has primary output some 10-formyltetrahydrofolate(2-))

• obsolete 10-formyltetrahydrofolate biosynthetic process SubClassOf 10-formyltetrahydrofolate metabolic process

• obsolete 10-formyltetrahydrofolate biosynthetic process SubClassOf dicarboxylic acid biosynthetic process

• obsolete 10-formyltetrahydrofolate biosynthetic process SubClassOf tetrahydrofolate biosynthetic process

• obsolete 10-formyltetrahydrofolate biosynthetic process SubClassOf has primary output some 10-formyltetrahydrofolate(2-)

Added

• obsolete 10-formyltetrahydrofolate biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/32289”^^anyURI

• obsolete 10-formyltetrahydrofolate biosynthetic process term replaced by folate cycle

• obsolete 10-formyltetrahydrofolate biosynthetic process definition “OBSOLETE. The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.”
  • database_cross_reference “GOC:ai”

• obsolete 10-formyltetrahydrofolate biosynthetic process deprecated true

• obsolete 10-formyltetrahydrofolate biosynthetic process comment “This term was obsoleted because it represents the same process as folate cycle ; GO:0035999.”

• obsolete 10-formyltetrahydrofolate biosynthetic process label “obsolete 10-formyltetrahydrofolate biosynthetic process”

obsolete 17-methylnonadec-1-ene biosynthetic process http://purl.obolibrary.org/obo/GO_1900883

Removed

• obsolete 17-methylnonadec-1-ene biosynthetic process conformsTo biosynthetic_process.yaml

obsolete 17-methylnonadec-1-ene metabolic process http://purl.obolibrary.org/obo/GO_1900882

Removed

• obsolete 17-methylnonadec-1-ene metabolic process conformsTo metabolic_process.yaml

obsolete 18-methylnonadec-1-ene biosynthetic process http://purl.obolibrary.org/obo/GO_1900881

Removed

• obsolete 18-methylnonadec-1-ene biosynthetic process conformsTo biosynthetic_process.yaml

obsolete 18-methylnonadec-1-ene metabolic process http://purl.obolibrary.org/obo/GO_1900880

Removed

• obsolete 18-methylnonadec-1-ene metabolic process conformsTo metabolic_process.yaml

obsolete 3-chloroacrylic acid metabolic process http://purl.obolibrary.org/obo/GO_0018888

Removed

• obsolete 3-chloroacrylic acid metabolic process conformsTo metabolic_process.yaml

obsolete 3-hydroxybenzyl alcohol metabolic process http://purl.obolibrary.org/obo/GO_0018921

Removed

• obsolete 3-hydroxybenzyl alcohol metabolic process conformsTo metabolic_process.yaml

obsolete 4-carboxy-4’-sulfoazobenzene metabolic process http://purl.obolibrary.org/obo/GO_0018887

Removed

• obsolete 4-carboxy-4’-sulfoazobenzene metabolic process conformsTo metabolic_process.yaml

obsolete 7-cyano-7-deazaguanine metabolic process http://purl.obolibrary.org/obo/GO_0097287

Removed

• obsolete 7-cyano-7-deazaguanine metabolic process conformsTo metabolic_process.yaml

obsolete FADH2 metabolic process http://purl.obolibrary.org/obo/GO_0006746

Removed

• obsolete FADH2 metabolic process conformsTo metabolic_process.yaml

obsolete K antigen metabolic process http://purl.obolibrary.org/obo/GO_0046375

Removed

• obsolete K antigen metabolic process conformsTo metabolic_process.yaml

obsolete aldoxime metabolic process http://purl.obolibrary.org/obo/GO_0019330

Removed

• obsolete aldoxime metabolic process conformsTo metabolic_process.yaml

obsolete benzonitrile metabolic process http://purl.obolibrary.org/obo/GO_0018876

Removed

• obsolete benzonitrile metabolic process conformsTo metabolic_process.yaml

obsolete beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process http://purl.obolibrary.org/obo/GO_0018877

Removed

• obsolete beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process conformsTo metabolic_process.yaml

obsolete bromoxynil metabolic process http://purl.obolibrary.org/obo/GO_0018881

Removed

• obsolete bromoxynil metabolic process conformsTo metabolic_process.yaml

obsolete cellodextrin metabolic process http://purl.obolibrary.org/obo/GO_2000889

Removed

• obsolete cellodextrin metabolic process conformsTo metabolic_process.yaml

obsolete cellotriose metabolic process http://purl.obolibrary.org/obo/GO_2000893

Removed

• obsolete cellotriose metabolic process conformsTo metabolic_process.yaml

obsolete cephalosporin C metabolic process http://purl.obolibrary.org/obo/GO_1901266

Removed

• obsolete cephalosporin C metabolic process conformsTo metabolic_process.yaml

obsolete cordyol C biosynthetic process http://purl.obolibrary.org/obo/GO_1900799

Removed

• obsolete cordyol C biosynthetic process conformsTo biosynthetic_process.yaml

obsolete cordyol C catabolic process http://purl.obolibrary.org/obo/GO_1900798

Removed

• obsolete cordyol C catabolic process conformsTo catabolic_process.yaml

obsolete cordyol C metabolic process http://purl.obolibrary.org/obo/GO_1900797

Removed

• obsolete cordyol C metabolic process conformsTo metabolic_process.yaml

obsolete cyclohexylsulfamate metabolic process http://purl.obolibrary.org/obo/GO_0018892

Removed

• obsolete cyclohexylsulfamate metabolic process conformsTo metabolic_process.yaml

obsolete diaminopimelate biosynthetic process http://purl.obolibrary.org/obo/GO_0019877

Removed

• obsolete diaminopimelate biosynthetic process consider L-leucine biosynthetic process

• obsolete diaminopimelate biosynthetic process comment “This term was obsoleted because it represents an intermediate in L-leucine biosynthesis.”

Added

• obsolete diaminopimelate biosynthetic process consider L-lysine biosynthetic process

• obsolete diaminopimelate biosynthetic process comment “This term was obsoleted because it represents an intermediate in L-lysine biosynthesis.”

obsolete dimethyl ether metabolic process http://purl.obolibrary.org/obo/GO_0018905

Removed

• obsolete dimethyl ether metabolic process conformsTo metabolic_process.yaml

obsolete dimethylsilanediol metabolic process http://purl.obolibrary.org/obo/GO_0046454

Removed

• obsolete dimethylsilanediol metabolic process conformsTo metabolic_process.yaml

obsolete diorcinol biosynthetic process http://purl.obolibrary.org/obo/GO_1900572

Removed

• obsolete diorcinol biosynthetic process conformsTo biosynthetic_process.yaml

obsolete diorcinol catabolic process http://purl.obolibrary.org/obo/GO_1900571

Removed

• obsolete diorcinol catabolic process conformsTo catabolic_process.yaml

obsolete diorcinol metabolic process http://purl.obolibrary.org/obo/GO_1900570

Removed

• obsolete diorcinol metabolic process conformsTo metabolic_process.yaml

obsolete ent-kaurene metabolic process http://purl.obolibrary.org/obo/GO_0033331

Removed

• obsolete ent-kaurene metabolic process definition “The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.”

  • database_cross_reference “GOC:mah”

  • database_cross_reference “PMID:17064690”

• obsolete ent-kaurene metabolic process label “ent-kaurene metabolic process”

• obsolete ent-kaurene metabolic process EquivalentTo metabolic process and (has primary input or output some ent-kaurene)

• obsolete ent-kaurene metabolic process SubClassOf terpene metabolic process

• obsolete ent-kaurene metabolic process SubClassOf has primary input or output some ent-kaurene

Added

• obsolete ent-kaurene metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/28120”^^anyURI

• obsolete ent-kaurene metabolic process consider ent-kaurene biosynthetic process

• obsolete ent-kaurene metabolic process definition “OBSOLETE. The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.”

  • database_cross_reference “GOC:mah”

  • database_cross_reference “PMID:17064690”

• obsolete ent-kaurene metabolic process deprecated true

• obsolete ent-kaurene metabolic process comment “The reason for obsoletion is that this term was an unnecessary grouping term.”

• obsolete ent-kaurene metabolic process label “obsolete ent-kaurene metabolic process”

obsolete envenomation resulting in occlusion of the pore of voltage-gated potassium channel http://purl.obolibrary.org/obo/GO_0044564

Removed

• obsolete envenomation resulting in occlusion of the pore of voltage-gated potassium channel term replaced by obsolete venom-mediated inhibition of voltage-gated potassium channel activity

obsolete envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel http://purl.obolibrary.org/obo/GO_0044563

Removed

• obsolete envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel term replaced by obsolete venom-mediated inhibition of voltage-gated potassium channel activity

obsolete establishment of central gap gene boundaries http://purl.obolibrary.org/obo/GO_0007358

Removed

• obsolete establishment of central gap gene boundaries definition “OBSOLETE. Specification of the borders of central gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by knirps repression of Kruppel.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• obsolete establishment of central gap gene boundaries term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• obsolete establishment of central gap gene boundaries definition “OBSOLETE. Specification of the borders of central gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by knirps repression of Kruppel.”

  • database_cross_reference “ISBN:0879694238”

obsolete establishment of posterior gap gene boundaries http://purl.obolibrary.org/obo/GO_0007361

Removed

• obsolete establishment of posterior gap gene boundaries definition “OBSOLETE. Specification of the borders of posterior gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by hunchback and tailless repression of knirps.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• obsolete establishment of posterior gap gene boundaries definition “OBSOLETE. Specification of the borders of posterior gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by hunchback and tailless repression of knirps.”
  • database_cross_reference “ISBN:0879694238”

obsolete establishment of terminal gap gene boundary http://purl.obolibrary.org/obo/GO_0007364

Removed

• obsolete establishment of terminal gap gene boundary definition “OBSOLETE. Specification of the borders of terminal gap gene expression mediated largely by the effects of other gap genes.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• obsolete establishment of terminal gap gene boundary definition “OBSOLETE. Specification of the borders of terminal gap gene expression mediated largely by the effects of other gap genes.”
  • database_cross_reference “ISBN:0879694238”

obsolete establishment or maintenance of bipolar cell polarity regulating cell shape http://purl.obolibrary.org/obo/GO_0061246

Removed

• obsolete establishment or maintenance of bipolar cell polarity regulating cell shape definition “Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:vw”

• obsolete establishment or maintenance of bipolar cell polarity regulating cell shape label “establishment or maintenance of bipolar cell polarity regulating cell shape”

• obsolete establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf establishment or maintenance of bipolar cell polarity

• obsolete establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf establishment or maintenance of cell polarity regulating cell shape

• obsolete establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

Added

• obsolete establishment or maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI

• obsolete establishment or maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity

• obsolete establishment or maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:vw”

• obsolete establishment or maintenance of bipolar cell polarity regulating cell shape deprecated true

• obsolete establishment or maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”

• obsolete establishment or maintenance of bipolar cell polarity regulating cell shape label “obsolete establishment or maintenance of bipolar cell polarity regulating cell shape”

obsolete gentamycin catabolic process http://purl.obolibrary.org/obo/GO_1901129

Removed

• obsolete gentamycin catabolic process conformsTo catabolic_process.yaml

obsolete gentamycin metabolic process http://purl.obolibrary.org/obo/GO_1901128

Removed

• obsolete gentamycin metabolic process conformsTo metabolic_process.yaml

obsolete heptadecane metabolic process http://purl.obolibrary.org/obo/GO_1900635

Removed

• obsolete heptadecane metabolic process conformsTo metabolic_process.yaml

obsolete iprodione metabolic process http://purl.obolibrary.org/obo/GO_0018922

Removed

• obsolete iprodione metabolic process conformsTo metabolic_process.yaml

obsolete isoprene biosynthetic process http://purl.obolibrary.org/obo/GO_0043612

Removed

• obsolete isoprene biosynthetic process conformsTo biosynthetic_process.yaml

obsolete isoprene metabolic process http://purl.obolibrary.org/obo/GO_0043611

Removed

• obsolete isoprene metabolic process conformsTo metabolic_process.yaml

obsolete macromolecule depalmitoylation http://purl.obolibrary.org/obo/GO_0098734

Removed

• obsolete macromolecule depalmitoylation definition “The removal of palymitoyl groups from a macromolecule.”
  • database_cross_reference “GOC:dos”

• obsolete macromolecule depalmitoylation label “macromolecule depalmitoylation”

• obsolete macromolecule depalmitoylation SubClassOf macromolecule deacylation

Added

• obsolete macromolecule depalmitoylation term tracker item “https://github.com/geneontology/go-ontology/issues/32290”^^anyURI

• obsolete macromolecule depalmitoylation consider palmitoyl-(protein) hydrolase activity

• obsolete macromolecule depalmitoylation consider palmitoyl hydrolase activity

• obsolete macromolecule depalmitoylation definition “OBSOLETE. The removal of palymitoyl groups from a macromolecule.”
  • database_cross_reference “GOC:dos”

• obsolete macromolecule depalmitoylation deprecated true

• obsolete macromolecule depalmitoylation comment “The reason for obsoletion is that this term represents a molecular function, not a biological process. Consider instead annotating to the molecular function ‘palmitoyl hydrolase activity’ (GO:0098599), or, for protein substrates, ‘palmitoyl-(protein) hydrolase activity’ (GO:0008474).”

• obsolete macromolecule depalmitoylation label “obsolete macromolecule depalmitoylation”

obsolete maintenance of bipolar cell polarity regulating cell shape http://purl.obolibrary.org/obo/GO_0061305

Removed

• obsolete maintenance of bipolar cell polarity regulating cell shape definition “The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:vw”

• obsolete maintenance of bipolar cell polarity regulating cell shape label “maintenance of bipolar cell polarity regulating cell shape”

• obsolete maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete establishment or maintenance of bipolar cell polarity regulating cell shape

• obsolete maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

Added

• obsolete maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI

• obsolete maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity

• obsolete maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:vw”

• obsolete maintenance of bipolar cell polarity regulating cell shape deprecated true

• obsolete maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that these terms were added in error.”

• obsolete maintenance of bipolar cell polarity regulating cell shape label “obsolete maintenance of bipolar cell polarity regulating cell shape”

obsolete maltoheptaose metabolic process http://purl.obolibrary.org/obo/GO_2001122

Removed

• obsolete maltoheptaose metabolic process conformsTo metabolic_process.yaml

obsolete membrane addition at site of mitotic cytokinesis http://purl.obolibrary.org/obo/GO_0061796

Removed

• obsolete membrane addition at site of mitotic cytokinesis definition “A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:vw”

• obsolete membrane addition at site of mitotic cytokinesis label “membrane addition at site of mitotic cytokinesis”

• obsolete membrane addition at site of mitotic cytokinesis EquivalentTo membrane addition at site of cytokinesis and (part of some mitotic cell cycle)

• obsolete membrane addition at site of mitotic cytokinesis SubClassOf membrane addition at site of cytokinesis

• obsolete membrane addition at site of mitotic cytokinesis SubClassOf mitotic cytokinetic process

• obsolete membrane addition at site of mitotic cytokinesis SubClassOf in taxon some Eukaryota

Added

• obsolete membrane addition at site of mitotic cytokinesis term tracker item “https://github.com/geneontology/go-ontology/issues/31687”^^anyURI

• obsolete membrane addition at site of mitotic cytokinesis consider exocytosis

• obsolete membrane addition at site of mitotic cytokinesis definition “OBSOLETE. A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:vw”

• obsolete membrane addition at site of mitotic cytokinesis deprecated true

• obsolete membrane addition at site of mitotic cytokinesis comment “The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.”

• obsolete membrane addition at site of mitotic cytokinesis label “obsolete membrane addition at site of mitotic cytokinesis”

obsolete methanesulfonic acid metabolic process http://purl.obolibrary.org/obo/GO_0018926

Removed

• obsolete methanesulfonic acid metabolic process conformsTo metabolic_process.yaml

obsolete methanophenazine metabolic process http://purl.obolibrary.org/obo/GO_1900629

Removed

• obsolete methanophenazine metabolic process conformsTo metabolic_process.yaml

obsolete methyl fluoride metabolic process http://purl.obolibrary.org/obo/GO_0018929

Removed

• obsolete methyl fluoride metabolic process conformsTo metabolic_process.yaml

obsolete methyl tert-butyl ether metabolic process http://purl.obolibrary.org/obo/GO_0018906

Removed

• obsolete methyl tert-butyl ether metabolic process conformsTo metabolic_process.yaml

obsolete mitochondrial protein-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0008566

Removed

• obsolete mitochondrial protein-transporting ATPase activity definition “Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.”
  • database_cross_reference “EC:7.4.2.3”

• obsolete mitochondrial protein-transporting ATPase activity comment “See also the cellular component term ‘mitochondrial inner membrane presequence translocase complex ; GO:0005744’.”

• obsolete mitochondrial protein-transporting ATPase activity label “mitochondrial protein-transporting ATPase activity”

• obsolete mitochondrial protein-transporting ATPase activity EquivalentTo protein-transporting ATPase activity and (occurs in some mitochondrion)

• obsolete mitochondrial protein-transporting ATPase activity SubClassOf protein-transporting ATPase activity

• obsolete mitochondrial protein-transporting ATPase activity SubClassOf occurs in some mitochondrion

Added

• obsolete mitochondrial protein-transporting ATPase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32393”^^anyURI

• obsolete mitochondrial protein-transporting ATPase activity definition “OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.”
  • database_cross_reference “EC:7.4.2.3”

• obsolete mitochondrial protein-transporting ATPase activity deprecated true

• obsolete mitochondrial protein-transporting ATPase activity comment “The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent.”

• obsolete mitochondrial protein-transporting ATPase activity label “obsolete mitochondrial protein-transporting ATPase activity”

obsolete monounsaturated fatty acid metabolic process http://purl.obolibrary.org/obo/GO_1903964

Removed

• obsolete monounsaturated fatty acid metabolic process conformsTo metabolic_process.yaml

obsolete naphthalenesulfonate metabolic process http://purl.obolibrary.org/obo/GO_0018984

Removed

• obsolete naphthalenesulfonate metabolic process conformsTo metabolic_process.yaml

obsolete negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process http://purl.obolibrary.org/obo/GO_1900942

Removed

• obsolete negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of 17-methylnonadec-1-ene biosynthetic process http://purl.obolibrary.org/obo/GO_1900957

Removed

• obsolete negative regulation of 17-methylnonadec-1-ene biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of 18-methylnonadec-1-ene biosynthetic process http://purl.obolibrary.org/obo/GO_1900951

Removed

• obsolete negative regulation of 18-methylnonadec-1-ene biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of cordyol C biosynthetic process http://purl.obolibrary.org/obo/GO_1900862

Removed

• obsolete negative regulation of cordyol C biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of diorcinol biosynthetic process http://purl.obolibrary.org/obo/GO_1900656

Removed

• obsolete negative regulation of diorcinol biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape http://purl.obolibrary.org/obo/GO_2000750

Removed

• obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape definition “Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.”
  • database_cross_reference “GOC:mah”

• obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape label “negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape”

• obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape EquivalentTo biological regulation and (negatively regulates some obsolete establishment or maintenance of bipolar cell polarity regulating cell shape)

• obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape

• obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf negative regulation of establishment or maintenance of cell polarity regulating cell shape

• obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

• obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf negatively regulates some obsolete establishment or maintenance of bipolar cell polarity regulating cell shape

Added

• obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI

• obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity

• obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.”
  • database_cross_reference “GOC:mah”

• obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape deprecated true

• obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”

• obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape label “obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape”

obsolete negative regulation of isoprene biosynthetic process http://purl.obolibrary.org/obo/GO_1900948

Removed

• obsolete negative regulation of isoprene biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape http://purl.obolibrary.org/obo/GO_0061362

Removed

• obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape definition “Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.”
  • database_cross_reference “GOC:dph”

• obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape label “negative regulation of maintenance of bipolar cell polarity regulating cell shape”

• obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of maintenance of bipolar cell polarity regulating cell shape

• obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape

• obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

• obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf negatively regulates some obsolete maintenance of bipolar cell polarity regulating cell shape

Added

• obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI

• obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity

• obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.”
  • database_cross_reference “GOC:dph”

• obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape deprecated true

• obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”

• obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape label “obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape”

obsolete negative regulation of nonadec-1-ene biosynthetic process http://purl.obolibrary.org/obo/GO_1900936

Removed

• obsolete negative regulation of nonadec-1-ene biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of octadecene biosynthetic process http://purl.obolibrary.org/obo/GO_1900915

Removed

• obsolete negative regulation of octadecene biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of palmitic acid catabolic process http://purl.obolibrary.org/obo/GO_0106394

Removed

• obsolete negative regulation of palmitic acid catabolic process conformsTo negative_regulation.yaml

obsolete negative regulation of tatiopterin biosynthetic process http://purl.obolibrary.org/obo/GO_1900975

Removed

• obsolete negative regulation of tatiopterin biosynthetic process conformsTo negative_regulation.yaml

obsolete nonadec-1-ene metabolic process http://purl.obolibrary.org/obo/GO_1900876

Removed

• obsolete nonadec-1-ene metabolic process conformsTo metabolic_process.yaml

obsolete ocellus pigment granule organization http://purl.obolibrary.org/obo/GO_0008058

Removed

• obsolete ocellus pigment granule organization definition “A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus.”
  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

• obsolete ocellus pigment granule organization label “ocellus pigment granule organization”

• obsolete ocellus pigment granule organization SubClassOf pigment granule organization

• obsolete ocellus pigment granule organization SubClassOf in taxon some cellular organisms

Added

• obsolete ocellus pigment granule organization term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• obsolete ocellus pigment granule organization definition “OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus.”
  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

• obsolete ocellus pigment granule organization deprecated true

• obsolete ocellus pigment granule organization comment “The reason for obsoletion is that this term was made in error.”

• obsolete ocellus pigment granule organization label “obsolete ocellus pigment granule organization”

obsolete octadecene biosynthetic process http://purl.obolibrary.org/obo/GO_1900682

Removed

• obsolete octadecene biosynthetic process conformsTo biosynthetic_process.yaml

obsolete octadecene metabolic process http://purl.obolibrary.org/obo/GO_1900681

Removed

• obsolete octadecene metabolic process conformsTo metabolic_process.yaml

obsolete palmitic acid catabolic process http://purl.obolibrary.org/obo/GO_1900534

Removed

• obsolete palmitic acid catabolic process conformsTo catabolic_process.yaml

obsolete pentadecane metabolic process http://purl.obolibrary.org/obo/GO_1900633

Removed

• obsolete pentadecane metabolic process conformsTo metabolic_process.yaml

obsolete pentaerythritol tetranitrate metabolic process http://purl.obolibrary.org/obo/GO_0018954

Removed

• obsolete pentaerythritol tetranitrate metabolic process conformsTo metabolic_process.yaml

obsolete phosphinothricin catabolic process http://purl.obolibrary.org/obo/GO_1901765

Removed

• obsolete phosphinothricin catabolic process conformsTo catabolic_process.yaml

obsolete phosphinothricin metabolic process http://purl.obolibrary.org/obo/GO_1901764

Removed

• obsolete phosphinothricin metabolic process conformsTo metabolic_process.yaml

obsolete poly(hydroxyalkanoate) metabolic process http://purl.obolibrary.org/obo/GO_1901440

Removed

• obsolete poly(hydroxyalkanoate) metabolic process conformsTo metabolic_process.yaml

obsolete positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process http://purl.obolibrary.org/obo/GO_1900943

Removed

• obsolete positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of 17-methylnonadec-1-ene biosynthetic process http://purl.obolibrary.org/obo/GO_1900958

Removed

• obsolete positive regulation of 17-methylnonadec-1-ene biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of 18-methylnonadec-1-ene biosynthetic process http://purl.obolibrary.org/obo/GO_1900952

Removed

• obsolete positive regulation of 18-methylnonadec-1-ene biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of cordyol C biosynthetic process http://purl.obolibrary.org/obo/GO_1900863

Removed

• obsolete positive regulation of cordyol C biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of diorcinol biosynthetic process http://purl.obolibrary.org/obo/GO_1900657

Removed

• obsolete positive regulation of diorcinol biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape http://purl.obolibrary.org/obo/GO_0061161

Removed

• obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape definition “Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:vw”

• obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape label “positive regulation of establishment of bipolar cell polarity regulating cell shape”

• obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of establishment of bipolar cell polarity regulating cell shape

• obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf positive regulation of establishment of bipolar cell polarity

• obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape

• obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

Added

• obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI

• obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity

• obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:vw”

• obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape deprecated true

• obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”

• obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape label “obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape”

obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape http://purl.obolibrary.org/obo/GO_2000247

Removed

• obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape definition “Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.”
  • database_cross_reference “GOC:obol”

• obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape label “positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape”

• obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape EquivalentTo biological regulation and (positively regulates some obsolete establishment or maintenance of bipolar cell polarity regulating cell shape)

• obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape

• obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf positive regulation of establishment or maintenance of cell polarity regulating cell shape

• obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

• obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf positively regulates some obsolete establishment or maintenance of bipolar cell polarity regulating cell shape

Added

• obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI

• obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity

• obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.”
  • database_cross_reference “GOC:obol”

• obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape deprecated true

• obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that these terms were added in error.”

• obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape label “obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape”

obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape http://purl.obolibrary.org/obo/GO_0061361

Removed

• obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape definition “Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.”
  • database_cross_reference “GOC:dph”

• obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape label “positive regulation of maintenance of bipolar cell polarity regulating cell shape”

• obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of maintenance of bipolar cell polarity regulating cell shape

• obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape

• obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

• obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf positively regulates some obsolete maintenance of bipolar cell polarity regulating cell shape

Added

• obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI

• obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity

• obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.”
  • database_cross_reference “GOC:dph”

• obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape deprecated true

• obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”

• obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape label “obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape”

obsolete positive regulation of nonadec-1-ene biosynthetic process http://purl.obolibrary.org/obo/GO_1900937

Removed

• obsolete positive regulation of nonadec-1-ene biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of octadecene biosynthetic process http://purl.obolibrary.org/obo/GO_1900916

Removed

• obsolete positive regulation of octadecene biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of palmitic acid catabolic process http://purl.obolibrary.org/obo/GO_0106395

Removed

• obsolete positive regulation of palmitic acid catabolic process conformsTo positive_regulation.yaml

obsolete positive regulation of tatiopterin biosynthetic process http://purl.obolibrary.org/obo/GO_1900976

Removed

• obsolete positive regulation of tatiopterin biosynthetic process conformsTo positive_regulation.yaml

obsolete protein depalmitoylation http://purl.obolibrary.org/obo/GO_0002084

Removed

• obsolete protein depalmitoylation in_subset gocheck_obsoletion_candidate

• obsolete protein depalmitoylation definition “The removal of palymitoyl groups from a lipoprotein.”
  • database_cross_reference “GOC:hjd”

• obsolete protein depalmitoylation label “protein depalmitoylation”

• obsolete protein depalmitoylation SubClassOf protein deacylation

• obsolete protein depalmitoylation SubClassOf lipoprotein catabolic process

• obsolete protein depalmitoylation SubClassOf obsolete macromolecule depalmitoylation

Added

• obsolete protein depalmitoylation term tracker item “https://github.com/geneontology/go-ontology/issues/32290”^^anyURI

• obsolete protein depalmitoylation consider palmitoyl-(protein) hydrolase activity

• obsolete protein depalmitoylation definition “OBSOLETE. The removal of palymitoyl groups from a lipoprotein.”
  • database_cross_reference “GOC:hjd”

• obsolete protein depalmitoylation deprecated true

• obsolete protein depalmitoylation comment “The reason for obsoletion is that this term represents a molecular function, not a biological process. Consider instead annotating to the molecular function ‘palmitoyl-(protein) hydrolase activity’ (GO:0008474).”

• obsolete protein depalmitoylation label “obsolete protein depalmitoylation”

obsolete regulation of (Z)-nonadeca-1,14-diene biosynthetic process http://purl.obolibrary.org/obo/GO_1900941

Removed

• obsolete regulation of (Z)-nonadeca-1,14-diene biosynthetic process conformsTo regulation.yaml

• obsolete regulation of (Z)-nonadeca-1,14-diene biosynthetic process conformsTo regulation_by.yaml

obsolete regulation of 17-methylnonadec-1-ene biosynthetic process http://purl.obolibrary.org/obo/GO_1900956

Removed

• obsolete regulation of 17-methylnonadec-1-ene biosynthetic process conformsTo regulation.yaml

• obsolete regulation of 17-methylnonadec-1-ene biosynthetic process conformsTo regulation_by.yaml

obsolete regulation of 18-methylnonadec-1-ene biosynthetic process http://purl.obolibrary.org/obo/GO_1900950

Removed

• obsolete regulation of 18-methylnonadec-1-ene biosynthetic process conformsTo regulation.yaml

• obsolete regulation of 18-methylnonadec-1-ene biosynthetic process conformsTo regulation_by.yaml

obsolete regulation of cordyol C biosynthetic process http://purl.obolibrary.org/obo/GO_1900861

Removed

• obsolete regulation of cordyol C biosynthetic process conformsTo regulation.yaml

• obsolete regulation of cordyol C biosynthetic process conformsTo regulation_by.yaml

obsolete regulation of diorcinol biosynthetic process http://purl.obolibrary.org/obo/GO_1900655

Removed

• obsolete regulation of diorcinol biosynthetic process conformsTo regulation.yaml

• obsolete regulation of diorcinol biosynthetic process conformsTo regulation_by.yaml

obsolete regulation of establishment of bipolar cell polarity regulating cell shape http://purl.obolibrary.org/obo/GO_0061160

Removed

• obsolete regulation of establishment of bipolar cell polarity regulating cell shape definition “Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:vw”

• obsolete regulation of establishment of bipolar cell polarity regulating cell shape label “regulation of establishment of bipolar cell polarity regulating cell shape”

• obsolete regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf regulation of establishment of bipolar cell polarity

• obsolete regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape

• obsolete regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

Added

• obsolete regulation of establishment of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI

• obsolete regulation of establishment of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity

• obsolete regulation of establishment of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:vw”

• obsolete regulation of establishment of bipolar cell polarity regulating cell shape deprecated true

• obsolete regulation of establishment of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”

• obsolete regulation of establishment of bipolar cell polarity regulating cell shape label “obsolete regulation of establishment of bipolar cell polarity regulating cell shape”

obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape http://purl.obolibrary.org/obo/GO_2000100

Removed

• obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape definition “Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.”
  • database_cross_reference “GOC:obol”

• obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape label “regulation of establishment or maintenance of bipolar cell polarity regulating cell shape”

• obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape EquivalentTo biological regulation and (regulates some obsolete establishment or maintenance of bipolar cell polarity regulating cell shape)

• obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf regulation of establishment or maintenance of bipolar cell polarity

• obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf regulation of establishment or maintenance of cell polarity regulating cell shape

• obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

• obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf regulates some obsolete establishment or maintenance of bipolar cell polarity regulating cell shape

Added

• obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI

• obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity

• obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.”
  • database_cross_reference “GOC:obol”

• obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape deprecated true

• obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”

• obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape label “obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape”

obsolete regulation of isoprene biosynthetic process http://purl.obolibrary.org/obo/GO_1900947

Removed

• obsolete regulation of isoprene biosynthetic process conformsTo regulation.yaml

• obsolete regulation of isoprene biosynthetic process conformsTo regulation_by.yaml

obsolete regulation of maintenance of bipolar cell polarity regulating cell shape http://purl.obolibrary.org/obo/GO_2000115

Removed

• obsolete regulation of maintenance of bipolar cell polarity regulating cell shape definition “Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape.”
  • database_cross_reference “GOC:obol”

• obsolete regulation of maintenance of bipolar cell polarity regulating cell shape label “regulation of maintenance of bipolar cell polarity regulating cell shape”

• obsolete regulation of maintenance of bipolar cell polarity regulating cell shape EquivalentTo biological regulation and (regulates some obsolete maintenance of bipolar cell polarity regulating cell shape)

• obsolete regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape

• obsolete regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

• obsolete regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf regulates some obsolete maintenance of bipolar cell polarity regulating cell shape

Added

• obsolete regulation of maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI

• obsolete regulation of maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity

• obsolete regulation of maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape.”
  • database_cross_reference “GOC:obol”

• obsolete regulation of maintenance of bipolar cell polarity regulating cell shape deprecated true

• obsolete regulation of maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”

• obsolete regulation of maintenance of bipolar cell polarity regulating cell shape label “obsolete regulation of maintenance of bipolar cell polarity regulating cell shape”

obsolete regulation of nonadec-1-ene biosynthetic process http://purl.obolibrary.org/obo/GO_1900935

Removed

• obsolete regulation of nonadec-1-ene biosynthetic process conformsTo regulation.yaml

• obsolete regulation of nonadec-1-ene biosynthetic process conformsTo regulation_by.yaml

obsolete regulation of octadecene biosynthetic process http://purl.obolibrary.org/obo/GO_1900914

Removed

• obsolete regulation of octadecene biosynthetic process conformsTo regulation.yaml

• obsolete regulation of octadecene biosynthetic process conformsTo regulation_by.yaml

obsolete regulation of palmitic acid catabolic process http://purl.obolibrary.org/obo/GO_0106393

Removed

• obsolete regulation of palmitic acid catabolic process conformsTo regulation.yaml

• obsolete regulation of palmitic acid catabolic process conformsTo regulation_by.yaml

obsolete regulation of tatiopterin biosynthetic process http://purl.obolibrary.org/obo/GO_1900974

Removed

• obsolete regulation of tatiopterin biosynthetic process conformsTo regulation.yaml

• obsolete regulation of tatiopterin biosynthetic process conformsTo regulation_by.yaml

obsolete resveratrol binding http://purl.obolibrary.org/obo/GO_1905594

Removed

• obsolete resveratrol binding conformsTo binding.yaml

obsolete sarcinapterin metabolic process http://purl.obolibrary.org/obo/GO_1900867

Removed

• obsolete sarcinapterin metabolic process conformsTo metabolic_process.yaml

obsolete styrene metabolic process http://purl.obolibrary.org/obo/GO_0018966

Removed

• obsolete styrene metabolic process conformsTo metabolic_process.yaml

obsolete substrate localization to autophagosome http://purl.obolibrary.org/obo/GO_0061753

Removed

• obsolete substrate localization to autophagosome definition “The localization process by which an autophagic substrate is delivered to a forming autophagosome.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:PARL”

  • database_cross_reference “GOC:pad”

  • database_cross_reference “PMID:23545414”

• obsolete substrate localization to autophagosome label “substrate localization to autophagosome”

• obsolete substrate localization to autophagosome SubClassOf establishment of localization in cell

• obsolete substrate localization to autophagosome SubClassOf part of some autophagosome assembly

• obsolete substrate localization to autophagosome SubClassOf in taxon some Eukaryota

Added

• obsolete substrate localization to autophagosome term tracker item “https://github.com/geneontology/go-ontology/issues/32304”^^anyURI

• obsolete substrate localization to autophagosome definition “OBSOLETE. The localization process by which an autophagic substrate is delivered to a forming autophagosome.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:PARL”

  • database_cross_reference “GOC:pad”

  • database_cross_reference “PMID:23545414”

• obsolete substrate localization to autophagosome deprecated true

• obsolete substrate localization to autophagosome comment “The reason for obsoletion is that this term was an unnecessary grouping term: localization terms that are not transport terms are largely uninformative about biological process. The intended biology in every observed use is better captured by a specific selective-autophagy term (e.g. mitophagy, glycophagy, reticulophagy). See the annotation review at https://github.com/geneontology/go-annotation/issues/6497 for per-annotation transfer recommendations.”

• obsolete substrate localization to autophagosome label “obsolete substrate localization to autophagosome”

obsolete tRNA threonylcarbamoyladenosine metabolic process http://purl.obolibrary.org/obo/GO_0070525

Removed

• obsolete tRNA threonylcarbamoyladenosine metabolic process conformsTo metabolic_process.yaml

obsolete tatiopterin biosynthetic process http://purl.obolibrary.org/obo/GO_1900870

Removed

• obsolete tatiopterin biosynthetic process conformsTo biosynthetic_process.yaml

obsolete tatiopterin metabolic process http://purl.obolibrary.org/obo/GO_1900869

Removed

• obsolete tatiopterin metabolic process conformsTo metabolic_process.yaml

obsolete thioredoxin peroxidase activity http://purl.obolibrary.org/obo/GO_0008379

Removed

• obsolete thioredoxin peroxidase activity database_cross_reference “MetaCyc:RXN0-267”

• obsolete thioredoxin peroxidase activity database_cross_reference “RHEA:63528”

• obsolete thioredoxin peroxidase activity exactMatch 63528

• obsolete thioredoxin peroxidase activity definition “Catalysis of the reaction: [thioredoxin]-dithiol + H2O2 = [thioredoxin]-disulfide + H2O.”
  • database_cross_reference “RHEA:63528”

• obsolete thioredoxin peroxidase activity label “thioredoxin peroxidase activity”

• obsolete thioredoxin peroxidase activity SubClassOf thioredoxin-dependent peroxiredoxin activity

• obsolete thioredoxin peroxidase activity SubClassOf has participant some water

• obsolete thioredoxin peroxidase activity SubClassOf has participant some hydrogen peroxide

• obsolete thioredoxin peroxidase activity SubClassOf has participant some L-cysteine residue

• obsolete thioredoxin peroxidase activity SubClassOf has participant some L-cystine residue

Added

• obsolete thioredoxin peroxidase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32388”^^anyURI

• obsolete thioredoxin peroxidase activity term replaced by thioredoxin-dependent peroxiredoxin activity

• obsolete thioredoxin peroxidase activity definition “OBSOLETE. Catalysis of the reaction: [thioredoxin]-dithiol + H2O2 = [thioredoxin]-disulfide + H2O.”
  • database_cross_reference “RHEA:63528”

• obsolete thioredoxin peroxidase activity deprecated true

• obsolete thioredoxin peroxidase activity comment “This term was obsoleted because it is redundant with GO:0140824 thioredoxin-dependent peroxiredoxin activity. Both enzyme activities use thioredoxin; the nominal distinction was that GO:0008379/RHEA:63528 specified hydrogen peroxide as substrate while GO:0140824/RHEA:62620 uses a hydroperoxide (of which H2O2 is a subtype). RHEA:63528 has no proteins associated with it and this term has been misannotated for enzymes with broader hydroperoxide specificity.”

• obsolete thioredoxin peroxidase activity label “obsolete thioredoxin peroxidase activity”

obsolete toluene metabolic process http://purl.obolibrary.org/obo/GO_0018970

Removed

• obsolete toluene metabolic process conformsTo metabolic_process.yaml

obsolete tri-n-butyltin metabolic process http://purl.obolibrary.org/obo/GO_0018944

Removed

• obsolete tri-n-butyltin metabolic process conformsTo metabolic_process.yaml

obsolete tridecane metabolic process http://purl.obolibrary.org/obo/GO_1900631

Removed

• obsolete tridecane metabolic process conformsTo metabolic_process.yaml

obsolete venom-mediated activation of pH-gated ion channel activity http://purl.obolibrary.org/obo/GO_0044734

Removed

• obsolete venom-mediated activation of pH-gated ion channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated activation of pH-gated ion channel activity definition “A process in which an organism initiates, promotes, or enhances the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “PMID:23034652”

  • database_cross_reference “GOC:fj”

• obsolete venom-mediated activation of pH-gated ion channel activity label “venom-mediated activation of pH-gated ion channel activity”

• obsolete venom-mediated activation of pH-gated ion channel activity EquivalentTo venom-mediated perturbation of biological process and (positively regulates in another organism some pH-gated monoatomic ion channel activity)

• obsolete venom-mediated activation of pH-gated ion channel activity SubClassOf obsolete venom-mediated perturbation of pH-gated ion channel activity

• obsolete venom-mediated activation of pH-gated ion channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated activation of pH-gated ion channel activity SubClassOf positively regulates in another organism some pH-gated monoatomic ion channel activity

Added

• obsolete venom-mediated activation of pH-gated ion channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated activation of pH-gated ion channel activity consider channel activator activity

• obsolete venom-mediated activation of pH-gated ion channel activity definition “OBSOLETE. A process in which an organism initiates, promotes, or enhances the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “PMID:23034652”

  • database_cross_reference “GOC:fj”

• obsolete venom-mediated activation of pH-gated ion channel activity deprecated true

• obsolete venom-mediated activation of pH-gated ion channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated activation of pH-gated ion channel activity label “obsolete venom-mediated activation of pH-gated ion channel activity”

obsolete venom-mediated activation of voltage-gated sodium channel activity http://purl.obolibrary.org/obo/GO_0044494

Removed

• obsolete venom-mediated activation of voltage-gated sodium channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated activation of voltage-gated sodium channel activity definition “A process in which an organism initiates, promotes, or enhances the activity of a voltage-gated sodium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:21781281”

• obsolete venom-mediated activation of voltage-gated sodium channel activity label “venom-mediated activation of voltage-gated sodium channel activity”

• obsolete venom-mediated activation of voltage-gated sodium channel activity EquivalentTo venom-mediated perturbation of biological process and (positively regulates in another organism some voltage-gated sodium channel activity)

• obsolete venom-mediated activation of voltage-gated sodium channel activity SubClassOf obsolete venom-mediated perturbation of voltage-gated sodium channel activity

• obsolete venom-mediated activation of voltage-gated sodium channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated activation of voltage-gated sodium channel activity SubClassOf positively regulates in another organism some voltage-gated sodium channel activity

Added

• obsolete venom-mediated activation of voltage-gated sodium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated activation of voltage-gated sodium channel activity consider sodium channel activator activity

• obsolete venom-mediated activation of voltage-gated sodium channel activity definition “OBSOLETE. A process in which an organism initiates, promotes, or enhances the activity of a voltage-gated sodium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:21781281”

• obsolete venom-mediated activation of voltage-gated sodium channel activity deprecated true

• obsolete venom-mediated activation of voltage-gated sodium channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated activation of voltage-gated sodium channel activity label “obsolete venom-mediated activation of voltage-gated sodium channel activity”

obsolete venom-mediated inhibition of calcium channel activity http://purl.obolibrary.org/obo/GO_0044473

Removed

• obsolete venom-mediated inhibition of calcium channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated inhibition of calcium channel activity definition “A process in which an organism inhibits or disrupts the activity of a calcium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:20920515”

• obsolete venom-mediated inhibition of calcium channel activity label “venom-mediated inhibition of calcium channel activity”

• obsolete venom-mediated inhibition of calcium channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some calcium channel activity)

• obsolete venom-mediated inhibition of calcium channel activity SubClassOf obsolete venom-mediated perturbation of calcium channel activity

• obsolete venom-mediated inhibition of calcium channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated inhibition of calcium channel activity SubClassOf negatively regulates in another organism some calcium channel activity

Added

• obsolete venom-mediated inhibition of calcium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated inhibition of calcium channel activity consider calcium channel inhibitor activity

• obsolete venom-mediated inhibition of calcium channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a calcium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:20920515”

• obsolete venom-mediated inhibition of calcium channel activity deprecated true

• obsolete venom-mediated inhibition of calcium channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated inhibition of calcium channel activity label “obsolete venom-mediated inhibition of calcium channel activity”

obsolete venom-mediated inhibition of high voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_0044475

Removed

• obsolete venom-mediated inhibition of high voltage-gated calcium channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated inhibition of high voltage-gated calcium channel activity definition “A process in which an organism inhibits or disrupts the activity of a high voltage-gated calcium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:20920515”

• obsolete venom-mediated inhibition of high voltage-gated calcium channel activity label “venom-mediated inhibition of high voltage-gated calcium channel activity”

• obsolete venom-mediated inhibition of high voltage-gated calcium channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some high voltage-gated calcium channel activity)

• obsolete venom-mediated inhibition of high voltage-gated calcium channel activity SubClassOf obsolete venom-mediated inhibition of voltage-gated calcium channel activity

• obsolete venom-mediated inhibition of high voltage-gated calcium channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated inhibition of high voltage-gated calcium channel activity SubClassOf negatively regulates in another organism some high voltage-gated calcium channel activity

Added

• obsolete venom-mediated inhibition of high voltage-gated calcium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated inhibition of high voltage-gated calcium channel activity consider calcium channel inhibitor activity

• obsolete venom-mediated inhibition of high voltage-gated calcium channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a high voltage-gated calcium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:20920515”

• obsolete venom-mediated inhibition of high voltage-gated calcium channel activity deprecated true

• obsolete venom-mediated inhibition of high voltage-gated calcium channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated inhibition of high voltage-gated calcium channel activity label “obsolete venom-mediated inhibition of high voltage-gated calcium channel activity”

obsolete venom-mediated inhibition of low voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_0044476

Removed

• obsolete venom-mediated inhibition of low voltage-gated calcium channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated inhibition of low voltage-gated calcium channel activity definition “A process in which an organism inhibits or disrupts the activity of a low voltage-gated calcium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:20920515”

• obsolete venom-mediated inhibition of low voltage-gated calcium channel activity label “venom-mediated inhibition of low voltage-gated calcium channel activity”

• obsolete venom-mediated inhibition of low voltage-gated calcium channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some low voltage-gated calcium channel activity)

• obsolete venom-mediated inhibition of low voltage-gated calcium channel activity SubClassOf obsolete venom-mediated inhibition of voltage-gated calcium channel activity

• obsolete venom-mediated inhibition of low voltage-gated calcium channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated inhibition of low voltage-gated calcium channel activity SubClassOf negatively regulates in another organism some low voltage-gated calcium channel activity

Added

• obsolete venom-mediated inhibition of low voltage-gated calcium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated inhibition of low voltage-gated calcium channel activity consider calcium channel inhibitor activity

• obsolete venom-mediated inhibition of low voltage-gated calcium channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a low voltage-gated calcium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:20920515”

• obsolete venom-mediated inhibition of low voltage-gated calcium channel activity deprecated true

• obsolete venom-mediated inhibition of low voltage-gated calcium channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated inhibition of low voltage-gated calcium channel activity label “obsolete venom-mediated inhibition of low voltage-gated calcium channel activity”

obsolete venom-mediated inhibition of pH-gated ion channel activity http://purl.obolibrary.org/obo/GO_0044735

Removed

• obsolete venom-mediated inhibition of pH-gated ion channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated inhibition of pH-gated ion channel activity definition “A process in which an organism inhibits or disrupts the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “PMID:23034652”

  • database_cross_reference “GOC:fj”

• obsolete venom-mediated inhibition of pH-gated ion channel activity label “venom-mediated inhibition of pH-gated ion channel activity”

• obsolete venom-mediated inhibition of pH-gated ion channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some pH-gated monoatomic ion channel activity)

• obsolete venom-mediated inhibition of pH-gated ion channel activity SubClassOf obsolete venom-mediated perturbation of pH-gated ion channel activity

• obsolete venom-mediated inhibition of pH-gated ion channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated inhibition of pH-gated ion channel activity SubClassOf negatively regulates in another organism some pH-gated monoatomic ion channel activity

Added

• obsolete venom-mediated inhibition of pH-gated ion channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated inhibition of pH-gated ion channel activity consider ion channel inhibitor activity

• obsolete venom-mediated inhibition of pH-gated ion channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “PMID:23034652”

  • database_cross_reference “GOC:fj”

• obsolete venom-mediated inhibition of pH-gated ion channel activity deprecated true

• obsolete venom-mediated inhibition of pH-gated ion channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated inhibition of pH-gated ion channel activity label “obsolete venom-mediated inhibition of pH-gated ion channel activity”

obsolete venom-mediated inhibition of voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_0044474

Removed

• obsolete venom-mediated inhibition of voltage-gated calcium channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated inhibition of voltage-gated calcium channel activity definition “A process in which an organism inhibits or disrupts the activity of a voltage-gated calcium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:20920515”

• obsolete venom-mediated inhibition of voltage-gated calcium channel activity label “venom-mediated inhibition of voltage-gated calcium channel activity”

• obsolete venom-mediated inhibition of voltage-gated calcium channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some voltage-gated calcium channel activity)

• obsolete venom-mediated inhibition of voltage-gated calcium channel activity SubClassOf obsolete venom-mediated inhibition of calcium channel activity

• obsolete venom-mediated inhibition of voltage-gated calcium channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated inhibition of voltage-gated calcium channel activity SubClassOf negatively regulates in another organism some voltage-gated calcium channel activity

Added

• obsolete venom-mediated inhibition of voltage-gated calcium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated inhibition of voltage-gated calcium channel activity consider calcium channel inhibitor activity

• obsolete venom-mediated inhibition of voltage-gated calcium channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a voltage-gated calcium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:20920515”

• obsolete venom-mediated inhibition of voltage-gated calcium channel activity deprecated true

• obsolete venom-mediated inhibition of voltage-gated calcium channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated inhibition of voltage-gated calcium channel activity label “obsolete venom-mediated inhibition of voltage-gated calcium channel activity”

obsolete venom-mediated inhibition of voltage-gated potassium channel activity http://purl.obolibrary.org/obo/GO_0044562

Removed

• obsolete venom-mediated inhibition of voltage-gated potassium channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated inhibition of voltage-gated potassium channel activity definition “A process in which an organism inhibits or disrupts the activity of a voltage-gated potassium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

• obsolete venom-mediated inhibition of voltage-gated potassium channel activity label “venom-mediated inhibition of voltage-gated potassium channel activity”

• obsolete venom-mediated inhibition of voltage-gated potassium channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some voltage-gated potassium channel activity)

• obsolete venom-mediated inhibition of voltage-gated potassium channel activity SubClassOf obsolete venom-mediated perturbation of voltage-gated potassium channel activity

• obsolete venom-mediated inhibition of voltage-gated potassium channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated inhibition of voltage-gated potassium channel activity SubClassOf negatively regulates in another organism some voltage-gated potassium channel activity

Added

• obsolete venom-mediated inhibition of voltage-gated potassium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated inhibition of voltage-gated potassium channel activity consider voltage-gated potassium channel inhibitor activity

• obsolete venom-mediated inhibition of voltage-gated potassium channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a voltage-gated potassium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

• obsolete venom-mediated inhibition of voltage-gated potassium channel activity deprecated true

• obsolete venom-mediated inhibition of voltage-gated potassium channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated inhibition of voltage-gated potassium channel activity label “obsolete venom-mediated inhibition of voltage-gated potassium channel activity”

obsolete venom-mediated inhibition of voltage-gated sodium channel activity http://purl.obolibrary.org/obo/GO_0044493

Removed

• obsolete venom-mediated inhibition of voltage-gated sodium channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated inhibition of voltage-gated sodium channel activity definition “A process in which an organism inhibits or disrupts the activity of a voltage-gated sodium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:21781281”

• obsolete venom-mediated inhibition of voltage-gated sodium channel activity label “venom-mediated inhibition of voltage-gated sodium channel activity”

• obsolete venom-mediated inhibition of voltage-gated sodium channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some voltage-gated sodium channel activity)

• obsolete venom-mediated inhibition of voltage-gated sodium channel activity SubClassOf obsolete venom-mediated perturbation of voltage-gated sodium channel activity

• obsolete venom-mediated inhibition of voltage-gated sodium channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated inhibition of voltage-gated sodium channel activity SubClassOf negatively regulates in another organism some voltage-gated sodium channel activity

Added

• obsolete venom-mediated inhibition of voltage-gated sodium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated inhibition of voltage-gated sodium channel activity consider sodium channel inhibitor activity

• obsolete venom-mediated inhibition of voltage-gated sodium channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a voltage-gated sodium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:21781281”

• obsolete venom-mediated inhibition of voltage-gated sodium channel activity deprecated true

• obsolete venom-mediated inhibition of voltage-gated sodium channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated inhibition of voltage-gated sodium channel activity label “obsolete venom-mediated inhibition of voltage-gated sodium channel activity”

obsolete venom-mediated perturbation of calcium channel activity http://purl.obolibrary.org/obo/GO_0044472

Removed

• obsolete venom-mediated perturbation of calcium channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated perturbation of calcium channel activity definition “A process in which an organism alters or subverts the activity of a calcium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:20920515”

• obsolete venom-mediated perturbation of calcium channel activity label “venom-mediated perturbation of calcium channel activity”

• obsolete venom-mediated perturbation of calcium channel activity EquivalentTo venom-mediated perturbation of biological process and (regulates in another organism some calcium channel activity)

• obsolete venom-mediated perturbation of calcium channel activity SubClassOf obsolete venom-mediated perturbation of ion channel activity

• obsolete venom-mediated perturbation of calcium channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated perturbation of calcium channel activity SubClassOf regulates in another organism some calcium channel activity

Added

• obsolete venom-mediated perturbation of calcium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated perturbation of calcium channel activity consider calcium channel regulator activity

• obsolete venom-mediated perturbation of calcium channel activity definition “OBSOLETE. A process in which an organism alters or subverts the activity of a calcium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:20920515”

• obsolete venom-mediated perturbation of calcium channel activity deprecated true

• obsolete venom-mediated perturbation of calcium channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated perturbation of calcium channel activity label “obsolete venom-mediated perturbation of calcium channel activity”

obsolete venom-mediated perturbation of ion channel activity http://purl.obolibrary.org/obo/GO_0044560

Removed

• obsolete venom-mediated perturbation of ion channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated perturbation of ion channel activity definition “A process in which an organism alters or subverts the activity of an ion channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

• obsolete venom-mediated perturbation of ion channel activity label “venom-mediated perturbation of ion channel activity”

• obsolete venom-mediated perturbation of ion channel activity EquivalentTo venom-mediated perturbation of biological process and (regulates in another organism some monoatomic ion channel activity)

• obsolete venom-mediated perturbation of ion channel activity SubClassOf venom-mediated perturbation of biological process

• obsolete venom-mediated perturbation of ion channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated perturbation of ion channel activity SubClassOf regulates in another organism some monoatomic ion channel activity

Added

• obsolete venom-mediated perturbation of ion channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated perturbation of ion channel activity definition “OBSOLETE. A process in which an organism alters or subverts the activity of an ion channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

• obsolete venom-mediated perturbation of ion channel activity deprecated true

• obsolete venom-mediated perturbation of ion channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated perturbation of ion channel activity label “obsolete venom-mediated perturbation of ion channel activity”

obsolete venom-mediated perturbation of pH-gated ion channel activity http://purl.obolibrary.org/obo/GO_0044733

Removed

• obsolete venom-mediated perturbation of pH-gated ion channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated perturbation of pH-gated ion channel activity definition “A process in which an organism alters or subverts the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “PMID:23034652”

  • database_cross_reference “GOC:fj”

• obsolete venom-mediated perturbation of pH-gated ion channel activity label “venom-mediated perturbation of pH-gated ion channel activity”

• obsolete venom-mediated perturbation of pH-gated ion channel activity EquivalentTo venom-mediated perturbation of biological process and (regulates in another organism some pH-gated monoatomic ion channel activity)

• obsolete venom-mediated perturbation of pH-gated ion channel activity SubClassOf obsolete venom-mediated perturbation of ion channel activity

• obsolete venom-mediated perturbation of pH-gated ion channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated perturbation of pH-gated ion channel activity SubClassOf regulates in another organism some pH-gated monoatomic ion channel activity

Added

• obsolete venom-mediated perturbation of pH-gated ion channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated perturbation of pH-gated ion channel activity consider ion channel regulator activity

• obsolete venom-mediated perturbation of pH-gated ion channel activity definition “OBSOLETE. A process in which an organism alters or subverts the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “PMID:23034652”

  • database_cross_reference “GOC:fj”

• obsolete venom-mediated perturbation of pH-gated ion channel activity deprecated true

• obsolete venom-mediated perturbation of pH-gated ion channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated perturbation of pH-gated ion channel activity label “obsolete venom-mediated perturbation of pH-gated ion channel activity”

obsolete venom-mediated perturbation of voltage-gated potassium channel activity http://purl.obolibrary.org/obo/GO_0044559

Removed

• obsolete venom-mediated perturbation of voltage-gated potassium channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated perturbation of voltage-gated potassium channel activity definition “A process in which an organism alters or subverts the activity of a voltage-gated potassium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

• obsolete venom-mediated perturbation of voltage-gated potassium channel activity label “venom-mediated perturbation of voltage-gated potassium channel activity”

• obsolete venom-mediated perturbation of voltage-gated potassium channel activity EquivalentTo venom-mediated perturbation of biological process and (regulates in another organism some voltage-gated potassium channel activity)

• obsolete venom-mediated perturbation of voltage-gated potassium channel activity SubClassOf obsolete venom-mediated perturbation of ion channel activity

• obsolete venom-mediated perturbation of voltage-gated potassium channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated perturbation of voltage-gated potassium channel activity SubClassOf regulates in another organism some voltage-gated potassium channel activity

Added

• obsolete venom-mediated perturbation of voltage-gated potassium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated perturbation of voltage-gated potassium channel activity consider potassium channel regulator activity

• obsolete venom-mediated perturbation of voltage-gated potassium channel activity definition “OBSOLETE. A process in which an organism alters or subverts the activity of a voltage-gated potassium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

• obsolete venom-mediated perturbation of voltage-gated potassium channel activity deprecated true

• obsolete venom-mediated perturbation of voltage-gated potassium channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated perturbation of voltage-gated potassium channel activity label “obsolete venom-mediated perturbation of voltage-gated potassium channel activity”

obsolete venom-mediated perturbation of voltage-gated sodium channel activity http://purl.obolibrary.org/obo/GO_0044492

Removed

• obsolete venom-mediated perturbation of voltage-gated sodium channel activity never in taxon Schizosaccharomyces

• obsolete venom-mediated perturbation of voltage-gated sodium channel activity definition “A process in which an organism alters or subverts the activity of a voltage-gated sodium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:21781281”

• obsolete venom-mediated perturbation of voltage-gated sodium channel activity label “venom-mediated perturbation of voltage-gated sodium channel activity”

• obsolete venom-mediated perturbation of voltage-gated sodium channel activity EquivalentTo venom-mediated perturbation of biological process and (regulates in another organism some voltage-gated sodium channel activity)

• obsolete venom-mediated perturbation of voltage-gated sodium channel activity SubClassOf obsolete venom-mediated perturbation of ion channel activity

• obsolete venom-mediated perturbation of voltage-gated sodium channel activity SubClassOf not (in taxon some Schizosaccharomyces)

• obsolete venom-mediated perturbation of voltage-gated sodium channel activity SubClassOf regulates in another organism some voltage-gated sodium channel activity

Added

• obsolete venom-mediated perturbation of voltage-gated sodium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI

• obsolete venom-mediated perturbation of voltage-gated sodium channel activity consider sodium channel regulator activity

• obsolete venom-mediated perturbation of voltage-gated sodium channel activity definition “OBSOLETE. A process in which an organism alters or subverts the activity of a voltage-gated sodium channel in another organism via the action of a venom.”

  • database_cross_reference “GOC:jl”

  • database_cross_reference “GOC:fj”

  • database_cross_reference “PMID:21781281”

• obsolete venom-mediated perturbation of voltage-gated sodium channel activity deprecated true

• obsolete venom-mediated perturbation of voltage-gated sodium channel activity comment “This term was obsoleted because it represents a molecular function.”

• obsolete venom-mediated perturbation of voltage-gated sodium channel activity label “obsolete venom-mediated perturbation of voltage-gated sodium channel activity”

obsolete very long-chain fatty acid beta-oxidation http://purl.obolibrary.org/obo/GO_0140493

Removed

• obsolete very long-chain fatty acid beta-oxidation definition “A fatty acid beta-oxidation pathway acting on a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons. The partway stars with the conversion of an acyl-CoA to a trans-2-enoyl-CoA, catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).”

  • database_cross_reference “PMID:32169171”

  • database_cross_reference “PMID:17028011”

  • database_cross_reference “GOC:ha”

• obsolete very long-chain fatty acid beta-oxidation comment “While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).”

• obsolete very long-chain fatty acid beta-oxidation label “very long-chain fatty acid beta-oxidation”

• obsolete very long-chain fatty acid beta-oxidation SubClassOf very long-chain fatty acid catabolic process

Added

• obsolete very long-chain fatty acid beta-oxidation term tracker item “https://github.com/geneontology/go-ontology/issues/32227”^^anyURI

• obsolete very long-chain fatty acid beta-oxidation term replaced by very long-chain fatty acid catabolic process

• obsolete very long-chain fatty acid beta-oxidation definition “OBSOLETE. A fatty acid beta-oxidation pathway acting on a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons. The partway stars with the conversion of an acyl-CoA to a trans-2-enoyl-CoA, catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).”

  • database_cross_reference “PMID:32169171”

  • database_cross_reference “PMID:17028011”

  • database_cross_reference “GOC:ha”

• obsolete very long-chain fatty acid beta-oxidation deprecated true

• obsolete very long-chain fatty acid beta-oxidation comment “This term was obsoleted because it represents the same process as very long-chain fatty acid catabolic process ; GO:0042760.”

• obsolete very long-chain fatty acid beta-oxidation label “obsolete very long-chain fatty acid beta-oxidation”

ocellus development http://purl.obolibrary.org/obo/GO_0008056

Removed

• ocellus development definition “The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects.”
  • database_cross_reference “http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004540”

Added

• ocellus development term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• ocellus development definition “The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects.”

  • database_cross_reference “FBbt:00004505”

ocellus morphogenesis http://purl.obolibrary.org/obo/GO_0048816

Removed

• ocellus morphogenesis definition “The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects.”
  • database_cross_reference “http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004540”

Added

• ocellus morphogenesis term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• ocellus morphogenesis definition “The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects.”

  • database_cross_reference “FBbt:00004505”

organophosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0090407

Added

• organophosphate biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI

• organophosphate biosynthetic process in_subset gocheck_do_not_annotate

organophosphate catabolic process http://purl.obolibrary.org/obo/GO_0046434

Added

• organophosphate catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI

• organophosphate catabolic process in_subset gocheck_do_not_annotate

organophosphate metabolic process http://purl.obolibrary.org/obo/GO_0019637

Added

• organophosphate metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI

• organophosphate metabolic process in_subset gocheck_do_not_annotate

otolith development http://purl.obolibrary.org/obo/GO_0048840

Removed

• otolith development conformsTo anatomical_structure_development.yaml

otolith formation http://purl.obolibrary.org/obo/GO_0032475

Removed

• otolith formation conformsTo anatomical_structure_formation.yaml

otolith morphogenesis http://purl.obolibrary.org/obo/GO_0032474

Removed

• otolith morphogenesis conformsTo anatomical_structure_morphogenesis.yaml

outward rectifier potassium channel inhibitor activity http://purl.obolibrary.org/obo/GO_0140628

Removed

• outward rectifier potassium channel inhibitor activity SubClassOf potassium channel inhibitor activity

Added

• outward rectifier potassium channel inhibitor activity SubClassOf voltage-gated potassium channel inhibitor activity

palmitoyl hydrolase activity http://purl.obolibrary.org/obo/GO_0098599

Removed

• palmitoyl hydrolase activity SubClassOf part of some obsolete macromolecule depalmitoylation

paranodal junction maintenance http://purl.obolibrary.org/obo/GO_1990227

Added

• paranodal junction maintenance never in taxon Fungi

• paranodal junction maintenance SubClassOf not (in taxon some Fungi)

periodic partitioning by pair rule gene http://purl.obolibrary.org/obo/GO_0007366

Removed

• periodic partitioning by pair rule gene definition “Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities.”

  • database_cross_reference “ISBN:0632030488”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• periodic partitioning by pair rule gene term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• periodic partitioning by pair rule gene definition “Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities.”

  • database_cross_reference “ISBN:0632030488”

  • database_cross_reference “ISBN:0879694238”

peroxiredoxin activity http://purl.obolibrary.org/obo/GO_0051920

Removed

• peroxiredoxin activity database_cross_reference “RHEA:62624”

• peroxiredoxin activity database_cross_reference “RHEA:62640”

• peroxiredoxin activity narrowMatch 62624

• peroxiredoxin activity narrowMatch 62640

• peroxiredoxin activity definition “Catalysis of the reaction: [protein]-dithol + ROOH = [protein]-disulfide + H2O + ROH.”

  • database_cross_reference “RHEA:10008”

Added

• peroxiredoxin activity term tracker item “https://github.com/geneontology/go-ontology/issues/32405”^^anyURI

• peroxiredoxin activity definition “Catalysis of the reaction: [protein]-dithiol + ROOH = [protein]-disulfide + H2O + ROH.”

  • database_cross_reference “RHEA:10008”

peroxisomal protein quality control http://purl.obolibrary.org/obo/GO_0170079

Added

• Class: peroxisomal protein quality control

• peroxisomal protein quality control term tracker item “https://github.com/geneontology/go-ontology/issues/32442”^^anyURI

• peroxisomal protein quality control created by “ew”

• peroxisomal protein quality control creation date “2026-08-12T16:13:58Z”

• peroxisomal protein quality control has_obo_namespace “biological_process”

• peroxisomal protein quality control id “GO:0170079”

• peroxisomal protein quality control definition “The chemical reactions and pathways resulting in the breakdown of dysfunctional peroxisomal proteins, independent of pexophagy.”

  • database_cross_reference “PMID:25305535”

  • database_cross_reference “PMID:37552037”

  • database_cross_reference “PMID:19538506”

• peroxisomal protein quality control label “peroxisomal protein quality control”

• peroxisomal protein quality control SubClassOf protein quality control

• peroxisomal protein quality control SubClassOf protein catabolic process

phagophore assembly site membrane http://purl.obolibrary.org/obo/GO_0034045

Removed

• phagophore assembly site membrane EquivalentTo membrane and (bounding layer of some phagophore assembly site)

• phagophore assembly site membrane SubClassOf bounding layer of some phagophore assembly site

phagosome maturation http://purl.obolibrary.org/obo/GO_0090382

Removed

• phagosome maturation SubClassOf starts with some exocytosis

Added

• phagosome maturation term tracker item “https://github.com/geneontology/go-ontology/issues/32152”^^anyURI

• phagosome maturation SubClassOf starts with some endocytosis

phosphocreatine biosynthetic process http://purl.obolibrary.org/obo/GO_0046314

Added

• phosphocreatine biosynthetic process never in taxon Archaea

• phosphocreatine biosynthetic process never in taxon Bacteria

• phosphocreatine biosynthetic process never in taxon Viridiplantae

• phosphocreatine biosynthetic process never in taxon Fungi

• phosphocreatine biosynthetic process never in taxon Insecta

• phosphocreatine biosynthetic process SubClassOf not (in taxon some Archaea)

• phosphocreatine biosynthetic process SubClassOf not (in taxon some Bacteria)

• phosphocreatine biosynthetic process SubClassOf not (in taxon some Viridiplantae)

• phosphocreatine biosynthetic process SubClassOf not (in taxon some Fungi)

• phosphocreatine biosynthetic process SubClassOf not (in taxon some Insecta)

phosphocreatine catabolic process http://purl.obolibrary.org/obo/GO_0046315

Added

• phosphocreatine catabolic process never in taxon Archaea

• phosphocreatine catabolic process never in taxon Bacteria

• phosphocreatine catabolic process never in taxon Viridiplantae

• phosphocreatine catabolic process never in taxon Fungi

• phosphocreatine catabolic process never in taxon Insecta

• phosphocreatine catabolic process SubClassOf not (in taxon some Archaea)

• phosphocreatine catabolic process SubClassOf not (in taxon some Bacteria)

• phosphocreatine catabolic process SubClassOf not (in taxon some Viridiplantae)

• phosphocreatine catabolic process SubClassOf not (in taxon some Fungi)

• phosphocreatine catabolic process SubClassOf not (in taxon some Insecta)

phosphocreatine metabolic process http://purl.obolibrary.org/obo/GO_0006603

Added

• phosphocreatine metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32279”^^anyURI

• phosphocreatine metabolic process never in taxon Archaea

• phosphocreatine metabolic process never in taxon Bacteria

• phosphocreatine metabolic process never in taxon Viridiplantae

• phosphocreatine metabolic process never in taxon Fungi

• phosphocreatine metabolic process never in taxon Insecta

• phosphocreatine metabolic process SubClassOf not (in taxon some Archaea)

• phosphocreatine metabolic process SubClassOf not (in taxon some Bacteria)

• phosphocreatine metabolic process SubClassOf not (in taxon some Viridiplantae)

• phosphocreatine metabolic process SubClassOf not (in taxon some Fungi)

• phosphocreatine metabolic process SubClassOf not (in taxon some Insecta)

plant anatomical entity http://purl.obolibrary.org/obo/PO_0025131

Added

• plant anatomical entity definition “An anatomical entity that is or was part of a plant.”

plasmodesma organization http://purl.obolibrary.org/obo/GO_0009663

Added

• plasmodesma organization never in taxon Fungi

• plasmodesma organization SubClassOf not (in taxon some Fungi)

positive regulation of ‘de novo’ NAD biosynthetic process from L-tryptophan http://purl.obolibrary.org/obo/GO_1905014

Added

• positive regulation of ‘de novo’ NAD biosynthetic process from L-tryptophan never in taxon Schizosaccharomyces pombe

• positive regulation of ‘de novo’ NAD biosynthetic process from L-tryptophan SubClassOf not (in taxon some Schizosaccharomyces pombe)

positive regulation of cristae formation http://purl.obolibrary.org/obo/GO_1903852

Removed

• positive regulation of cristae formation SubClassOf positive regulation of organelle organization

Added

• positive regulation of cristae formation SubClassOf positive regulation of cellular component organization

positive regulation of tight junction disassembly http://purl.obolibrary.org/obo/GO_1905075

Added

• positive regulation of tight junction disassembly never in taxon Fungi

• positive regulation of tight junction disassembly SubClassOf not (in taxon some Fungi)

posterior abdomen determination http://purl.obolibrary.org/obo/GO_0007359

Removed

• posterior abdomen determination definition “The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:isa_complete”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• posterior abdomen determination term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• posterior abdomen determination definition “The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:isa_complete”

  • database_cross_reference “ISBN:0879694238”

posterior compartment specification http://purl.obolibrary.org/obo/GO_0007388

Removed

• posterior compartment specification definition “The process involved in the specification of cell identity in the posterior compartments of the segmented embryo.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• posterior compartment specification term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• posterior compartment specification definition “The process involved in the specification of cell identity in the posterior compartments of the segmented embryo.”

  • database_cross_reference “ISBN:0879694238”

protein insertion into mitochondrial membrane http://purl.obolibrary.org/obo/GO_0051204

Removed

• protein insertion into mitochondrial membrane SubClassOf establishment of localization in cell

protein quality control http://purl.obolibrary.org/obo/GO_0006515

Removed

• protein quality control has_broad_synonym “protein quality control by the ubiquitin-proteasome system”

• protein quality control has exact synonym “degradation of misfolded or incompletely synthesized proteins”

• protein quality control has exact synonym “misfolded or incompletely synthesized protein breakdown”

• protein quality control has exact synonym “misfolded or incompletely synthesized protein catabolic process”

• protein quality control has exact synonym “misfolded or incompletely synthesized protein catabolism”

• protein quality control has exact synonym “misfolded or incompletely synthesized protein degradation”

• protein quality control has exact synonym “protein quality control (PQC)”

• protein quality control definition “The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.”
  • database_cross_reference “GOC:jl”

• protein quality control label “protein quality control for misfolded or incompletely synthesized proteins”

• protein quality control SubClassOf protein catabolic process

Added

• protein quality control term tracker item “https://github.com/geneontology/go-ontology/issues/32442”^^anyURI

• protein quality control has exact synonym “PQC”

• protein quality control has narrow synonym “degradation of misfolded or incompletely synthesized proteins”

• protein quality control has narrow synonym “misfolded or incompletely synthesized protein breakdown”

• protein quality control has narrow synonym “misfolded or incompletely synthesized protein catabolic process”

• protein quality control has narrow synonym “misfolded or incompletely synthesized protein catabolism”

• protein quality control has narrow synonym “misfolded or incompletely synthesized protein degradation”

• protein quality control has narrow synonym “protein quality control by the ubiquitin-proteasome system”

• protein quality control has narrow synonym “protein quality control for misfolded or incompletely synthesized proteins”

• protein quality control definition “The chemical reactions and pathways resulting in the breakdown or refolding of misfolded, dysfunctional, or incompletely synthesized proteins.”
  • database_cross_reference “PMID:21746797”

• protein quality control label “protein quality control”

• protein quality control SubClassOf cellular process

protein-N(PI)-phosphohistidine-carbohydrate phosphotransferase activity http://purl.obolibrary.org/obo/GO_0008982

Removed

• protein-N(PI)-phosphohistidine-carbohydrate phosphotransferase activity SubClassOf active transmembrane transporter activity

Added

• protein-N(PI)-phosphohistidine-carbohydrate phosphotransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/27496”^^anyURI

• protein-N(PI)-phosphohistidine-carbohydrate phosphotransferase activity SubClassOf group translocator activity

protein-containing complex http://purl.obolibrary.org/obo/GO_0032991

Added

• protein-containing complex definition “A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.”

protein-phosphocysteine-sugar phosphotransferase activity http://purl.obolibrary.org/obo/GO_0090563

Removed

• protein-phosphocysteine-sugar phosphotransferase activity SubClassOf active transmembrane transporter activity

Added

• protein-phosphocysteine-sugar phosphotransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/27496”^^anyURI

• protein-phosphocysteine-sugar phosphotransferase activity SubClassOf group translocator activity

protocatechuate 3,4-dioxygenase complex http://purl.obolibrary.org/obo/GO_7770085

Added

• protocatechuate 3,4-dioxygenase complex conformsTo protein_complex_by_activity.yaml

purine-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0072523

Removed

• purine-containing compound catabolic process SubClassOf catabolic process

Added

• purine-containing compound catabolic process SubClassOf nucleobase-containing small molecule catabolic process

rRNA (adenine-N6-)-methyltransferase activity http://purl.obolibrary.org/obo/GO_0008988

Removed

• rRNA (adenine-N6-)-methyltransferase activity SubClassOf N-methyltransferase activity

Added

• rRNA (adenine-N6-)-methyltransferase activity SubClassOf RNA (adenine-N6)-methyltransferase activity

regulation of ‘de novo’ NAD biosynthetic process from L-tryptophan http://purl.obolibrary.org/obo/GO_1905012

Added

• regulation of ‘de novo’ NAD biosynthetic process from L-tryptophan never in taxon Schizosaccharomyces pombe

• regulation of ‘de novo’ NAD biosynthetic process from L-tryptophan SubClassOf not (in taxon some Schizosaccharomyces pombe)

regulation of cristae formation http://purl.obolibrary.org/obo/GO_1903850

Removed

• regulation of cristae formation SubClassOf regulation of mitochondrion organization

Added

• regulation of cristae formation SubClassOf regulation of cellular component organization

regulation of tight junction disassembly http://purl.obolibrary.org/obo/GO_1905073

Added

• regulation of tight junction disassembly never in taxon Fungi

• regulation of tight junction disassembly SubClassOf not (in taxon some Fungi)

response to interleukin-5 http://purl.obolibrary.org/obo/GO_7770102

Added

• Class: response to interleukin-5

• response to interleukin-5 term tracker item “https://github.com/geneontology/go-ontology/issues/32411”^^anyURI

• response to interleukin-5 created by “ai4c-agent”

• response to interleukin-5 creation date “2026-08-04T23:16:15Z”

• response to interleukin-5 has exact synonym “response to IL-5”

• response to interleukin-5 has_obo_namespace “biological_process”

• response to interleukin-5 id “GO:7770102”

• response to interleukin-5 definition “Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-5 stimulus.”
  • database_cross_reference “PMID:41207640”

• response to interleukin-5 label “response to interleukin-5”

• response to interleukin-5 SubClassOf response to cytokine

riboflavin kinase activity http://purl.obolibrary.org/obo/GO_0008531

Removed

• riboflavin kinase activity definition “Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H+.”

  • database_cross_reference “EC:2.7.1.26”

  • database_cross_reference “RHEA:14357”

Added

• riboflavin kinase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32345”^^anyURI

• riboflavin kinase activity definition “Catalysis of the reaction: riboflavin + ATP = FMN + ADP + H+.”

  • database_cross_reference “RHEA:14357”

segment polarity determination http://purl.obolibrary.org/obo/GO_0007367

Removed

• segment polarity determination definition “Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products.”

  • database_cross_reference “ISBN:0632030488”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• segment polarity determination term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• segment polarity determination definition “Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products.”

  • database_cross_reference “ISBN:0632030488”

  • database_cross_reference “ISBN:0879694238”

segment specification http://purl.obolibrary.org/obo/GO_0007379

Removed

• segment specification definition “The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• segment specification term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• segment specification definition “The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.”

  • database_cross_reference “ISBN:0879694238”

sex comb development http://purl.obolibrary.org/obo/GO_0045498

Removed

• sex comb development definition “The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg.”
  • database_cross_reference “http://fly.ebi.ac.uk”

Added

• sex comb development term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• sex comb development definition “The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg.”

  • database_cross_reference “FBbt:00004296”

subtelomeric heterochromatin formation http://purl.obolibrary.org/obo/GO_0031509

Removed

• subtelomeric heterochromatin formation SubClassOf occurs in some chromosome, telomeric region

Added

• subtelomeric heterochromatin formation term tracker item “https://github.com/geneontology/go-ontology/issues/32403”^^anyURI

• subtelomeric heterochromatin formation EquivalentTo constitutive heterochromatin formation and (results in assembly of some subtelomeric heterochromatin)

• subtelomeric heterochromatin formation SubClassOf results in assembly of some subtelomeric heterochromatin

sulfate assimilation http://purl.obolibrary.org/obo/GO_0000103

Added

• sulfate assimilation term tracker item “https://github.com/geneontology/go-ontology/issues/32376”^^anyURI

• sulfate assimilation SubClassOf nutrient assimilation

tRNA(Val) (adenine(37)-N6)-methyltransferase activity http://purl.obolibrary.org/obo/GO_7770054

Removed

• tRNA(Val) (adenine(37)-N6)-methyltransferase activity SubClassOf N-methyltransferase activity

Added

• tRNA(Val) (adenine(37)-N6)-methyltransferase activity SubClassOf RNA (adenine-N6)-methyltransferase activity

terminal region determination http://purl.obolibrary.org/obo/GO_0007362

Removed

• terminal region determination definition “Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• terminal region determination term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• terminal region determination definition “Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products.”

  • database_cross_reference “ISBN:0879694238”

thioredoxin-dependent peroxiredoxin activity http://purl.obolibrary.org/obo/GO_0140824

Added

• thioredoxin-dependent peroxiredoxin activity term tracker item “https://github.com/geneontology/go-ontology/issues/32388”^^anyURI

• thioredoxin-dependent peroxiredoxin activity database_cross_reference “MetaCyc:RXN0-267”

• thioredoxin-dependent peroxiredoxin activity database_cross_reference “RHEA:63528”

• thioredoxin-dependent peroxiredoxin activity has exact synonym “TPx activity”

• thioredoxin-dependent peroxiredoxin activity has exact synonym “TrxPx activity”

• thioredoxin-dependent peroxiredoxin activity has exact synonym “thioredoxin peroxidase activity”

• thioredoxin-dependent peroxiredoxin activity has_related_synonym “thiol peroxidase activity”

• thioredoxin-dependent peroxiredoxin activity narrowMatch RXN0-267

• thioredoxin-dependent peroxiredoxin activity narrowMatch 63528

thorax and anterior abdomen determination http://purl.obolibrary.org/obo/GO_0007356

Removed

• thorax and anterior abdomen determination definition “Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• thorax and anterior abdomen determination term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• thorax and anterior abdomen determination definition “Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product.”

  • database_cross_reference “ISBN:0879694238”

tight junction disassembly http://purl.obolibrary.org/obo/GO_1905071

Added

• tight junction disassembly never in taxon Fungi

• tight junction disassembly SubClassOf not (in taxon some Fungi)

tight junction organization http://purl.obolibrary.org/obo/GO_0120193

Added

• tight junction organization never in taxon Fungi

• tight junction organization SubClassOf not (in taxon some Fungi)

tricellular tight junction disassembly http://purl.obolibrary.org/obo/GO_1904275

Added

• tricellular tight junction disassembly never in taxon Fungi

• tricellular tight junction disassembly SubClassOf not (in taxon some Fungi)

tripartite regional subdivision http://purl.obolibrary.org/obo/GO_0007351

Removed

• tripartite regional subdivision definition “Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:isa_complete”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• tripartite regional subdivision term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• tripartite regional subdivision definition “Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions.”

  • database_cross_reference “GOC:dph”

  • database_cross_reference “GOC:isa_complete”

  • database_cross_reference “ISBN:0879694238”

urate catabolic process http://purl.obolibrary.org/obo/GO_0019628

Removed

• urate catabolic process SubClassOf small molecule catabolic process

very long-chain fatty-acyl-CoA catabolic process http://purl.obolibrary.org/obo/GO_0036113

Removed

• very long-chain fatty-acyl-CoA catabolic process comment “While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).”

virion component http://purl.obolibrary.org/obo/GO_0044423

Added

• virion component definition “Any constituent part of a virion, a complete fully infectious extracellular virus particle.”

vitelline membrane formation http://purl.obolibrary.org/obo/GO_0030704

Removed

• vitelline membrane formation conformsTo anatomical_structure_formation.yaml

voltage-gated potassium channel inhibitor activity http://purl.obolibrary.org/obo/GO_7770090

Added

• Class: voltage-gated potassium channel inhibitor activity

• voltage-gated potassium channel inhibitor activity term tracker item “https://github.com/geneontology/go-ontology/issues/32371”^^anyURI

• voltage-gated potassium channel inhibitor activity created by “ai4c-agent”

• voltage-gated potassium channel inhibitor activity creation date “2026-07-28T16:49:43Z”

• voltage-gated potassium channel inhibitor activity has exact synonym “Kv channel inhibitor activity”

• voltage-gated potassium channel inhibitor activity has exact synonym “Kv inhibitor activity”

• voltage-gated potassium channel inhibitor activity has exact synonym “voltage-gated potassium channel (Kv) inhibitor activity”

• voltage-gated potassium channel inhibitor activity has_obo_namespace “molecular_function”

• voltage-gated potassium channel inhibitor activity id “GO:7770090”

• voltage-gated potassium channel inhibitor activity definition “Binds to and stops, prevents, or reduces the activity of a voltage-gated potassium channel.”
  • database_cross_reference “PMID:35797055”

• voltage-gated potassium channel inhibitor activity label “voltage-gated potassium channel inhibitor activity”

• voltage-gated potassium channel inhibitor activity EquivalentTo molecular function inhibitor activity and (directly negatively regulates some voltage-gated potassium channel activity)

• voltage-gated potassium channel inhibitor activity SubClassOf potassium channel inhibitor activity

• voltage-gated potassium channel inhibitor activity SubClassOf directly negatively regulates some voltage-gated potassium channel activity

zygotic determination of anterior/posterior axis, embryo http://purl.obolibrary.org/obo/GO_0007354

Removed

• zygotic determination of anterior/posterior axis, embryo definition “The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade.”

  • database_cross_reference “ISBN:0879694238”

  • database_cross_reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

• zygotic determination of anterior/posterior axis, embryo term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI

• zygotic determination of anterior/posterior axis, embryo definition “The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade.”

  • database_cross_reference “ISBN:0879694238”

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