go-ontology

Ontology comparison

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Ontology IRI: http://purl.obolibrary.org/obo/go/extensions/go-plus.ofn
Version IRI: http://purl.obolibrary.org/obo/go/releases/2026-07-26/extensions/go-plus.ofn
Loaded from: file:/__w/go-ontology/go-ontology/src/ontology/go-plus-lastrelease.owl

Right

Ontology IRI: http://purl.obolibrary.org/obo/go/extensions/go-plus.ofn
Version IRI: http://purl.obolibrary.org/obo/go/releases/2026-09-13/extensions/go-plus.ofn
Loaded from: file:/__w/go-ontology/go-ontology/src/ontology/extensions/go-plus.ofn

Ontology imports

Ontology annotations

Removed

versionInfo “2026-07-26”

Added

versionInfo “2026-09-13”

‘de novo’ NAD+ biosynthetic process from L-tryptophan `http://purl.obolibrary.org/obo/GO_0034354`

Added

‘de novo’ NAD+ biosynthetic process from L-tryptophan term tracker item “https://github.com/geneontology/go-ontology/issues/32456”^^anyURI
‘de novo’ NAD+ biosynthetic process from L-tryptophan never in taxon Schizosaccharomyces pombe
‘de novo’ NAD+ biosynthetic process from L-tryptophan SubClassOf not (in taxon some Schizosaccharomyces pombe)

(+)-larreatricin biosynthetic process `http://purl.obolibrary.org/obo/GO_1901709`

Removed

(+)-larreatricin biosynthetic process conformsTo metabolic_process.yaml

Added

(+)-larreatricin biosynthetic process conformsTo biosynthetic_process.yaml

(25S)-Delta(7)-dafachronate biosynthetic process `http://purl.obolibrary.org/obo/GO_1902056`

Removed

(25S)-Delta(7)-dafachronate biosynthetic process conformsTo metabolic_process.yaml

Added

(25S)-Delta(7)-dafachronate biosynthetic process conformsTo biosynthetic_process.yaml

(2R)-2-hydroxycarboxylate dehydrogenase (FAD) activity `http://purl.obolibrary.org/obo/GO_0140174`

Removed

(2R)-2-hydroxycarboxylate dehydrogenase (FAD) activity label “(2R)-2-hydroxycarboxylate dehydrogenase activity”

Added

(2R)-2-hydroxycarboxylate dehydrogenase (FAD) activity has_broad_synonym “(2R)-2-hydroxycarboxylate dehydrogenase activity”
(2R)-2-hydroxycarboxylate dehydrogenase (FAD) activity label “(2R)-2-hydroxycarboxylate dehydrogenase (FAD) activity”

(R)-mandelate dehydrogenase (NAD+) activity `http://purl.obolibrary.org/obo/GO_0097620`

Removed

(R)-mandelate dehydrogenase (NAD+) activity has exact synonym “D-mandelate dehydrogenase activity”
(R)-mandelate dehydrogenase (NAD+) activity label “(R)-mandelate dehydrogenase activity”
(R)-mandelate dehydrogenase (NAD+) activity SubClassOf oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Added

(R)-mandelate dehydrogenase (NAD+) activity term tracker item “https://github.com/geneontology/go-ontology/issues/32501”^^anyURI
(R)-mandelate dehydrogenase (NAD+) activity has_broad_synonym “(R)-mandelate dehydrogenase activity”
(R)-mandelate dehydrogenase (NAD+) activity has_broad_synonym “D-mandelate dehydrogenase activity”
(R)-mandelate dehydrogenase (NAD+) activity label “(R)-mandelate dehydrogenase (NAD+) activity”
(R)-mandelate dehydrogenase (NAD+) activity SubClassOf (2R)-2-hydroxyacid dehydrogenase (NAD+) activity

1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity `http://purl.obolibrary.org/obo/GO_0062181`

Removed

1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity definition “Catatlysis of the reaction: calcitriol + 2 H+ + O2 + 2 reduced [adrenodoxin] = 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin].”
- has cross-reference “PMID:30205156”
- has cross-reference “RHEA:49192”
- has cross-reference “PMID:22100522”

Added

1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity definition “Catalysis of the reaction: calcitriol + 2 H+ + O2 + 2 reduced [adrenodoxin] = 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin].”
- has cross-reference “PMID:30205156”
- has cross-reference “RHEA:49192”
- has cross-reference “PMID:22100522”

2-(3-amino-3-carboxypropyl)histidine synthase complex `http://purl.obolibrary.org/obo/GO_0120513`

Removed

2-(3-amino-3-carboxypropyl)histidine synthase complex definition “A protein complex capable of catalysing the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the histidine residue of translation elongation factor 2 (EF2), which is the first step in the biosynthesis of diphthamide. The complex is a Dph2 homodimer in archaea and a Dph1-Dph2 heterodimer in eukaryotes.”
- has cross-reference “PMID:31463593”
- has cross-reference “PMID:24422557”
- has cross-reference “GOC:sjm”

Added

2-(3-amino-3-carboxypropyl)histidine synthase complex definition “A protein complex capable of catalyzing the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the histidine residue of translation elongation factor 2 (EF2), which is the first step in the biosynthesis of diphthamide. The complex is a Dph2 homodimer in archaea and a Dph1-Dph2 heterodimer in eukaryotes.”
- has cross-reference “PMID:31463593”
- has cross-reference “PMID:24422557”
- has cross-reference “GOC:sjm”

2-oxoadipate decarboxylation to glutaryl-CoA `http://purl.obolibrary.org/obo/GO_0120578`

Added

Class: 2-oxoadipate decarboxylation to glutaryl-CoA
2-oxoadipate decarboxylation to glutaryl-CoA term tracker item “https://github.com/geneontology/go-ontology/issues/32557”^^anyURI
2-oxoadipate decarboxylation to glutaryl-CoA created by “sjm”
2-oxoadipate decarboxylation to glutaryl-CoA creation date “2026-09-03T06:52:01Z”
2-oxoadipate decarboxylation to glutaryl-CoA has_obo_namespace “biological_process”
2-oxoadipate decarboxylation to glutaryl-CoA id “GO:0120578”
2-oxoadipate decarboxylation to glutaryl-CoA definition “The chemical reactions and pathways resulting in the formation of glutaryl-CoA from 2-oxoadipate. In most organisms, this pathway is part of L-lysine, L-hydroxylysine and L-tryptophan degradation and comprises a series of three reactions carried out by a multisubunit complex called the ‘2-oxoadipate dehydrogenase complex’, even though 2-oxoadipate dehydrogenase activity describes only one of those reactions. The combination of the three reactions can be summarized as: 2-oxoadipate + coenzyme A + NAD+ -> glutaryl-CoA + CO2 + NADH.”
- has cross-reference “PMID:29191460”
2-oxoadipate decarboxylation to glutaryl-CoA label “2-oxoadipate decarboxylation to glutaryl-CoA”
2-oxoadipate decarboxylation to glutaryl-CoA EquivalentTo biosynthetic process and (has primary output some glutaryl-CoA(5-)) and (has primary input some 2-oxoadipate(2-))
2-oxoadipate decarboxylation to glutaryl-CoA SubClassOf dicarboxylic acid metabolic process
2-oxoadipate decarboxylation to glutaryl-CoA SubClassOf acyl-CoA biosynthetic process
2-oxoadipate decarboxylation to glutaryl-CoA SubClassOf fatty acid derivative biosynthetic process
2-oxoadipate decarboxylation to glutaryl-CoA SubClassOf has primary output some glutaryl-CoA(5-)
2-oxoadipate decarboxylation to glutaryl-CoA SubClassOf has primary input some 2-oxoadipate(2-)

2-oxoadipate dehydrogenase activity `http://purl.obolibrary.org/obo/GO_0160166`

Added

2-oxoadipate dehydrogenase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32557”^^anyURI
2-oxoadipate dehydrogenase activity broadMatch 30795

4’-phosphopantetheine phosphatase activity `http://purl.obolibrary.org/obo/GO_7770095`

Added

Class: 4’-phosphopantetheine phosphatase activity
4’-phosphopantetheine phosphatase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32389”^^anyURI
4’-phosphopantetheine phosphatase activity created by “ai4c-agent”
4’-phosphopantetheine phosphatase activity creation date “2026-07-30T17:40:49Z”
4’-phosphopantetheine phosphatase activity has cross-reference “EC:3.1.3.110”
4’-phosphopantetheine phosphatase activity has cross-reference “KEGG_REACTION:R10748”
4’-phosphopantetheine phosphatase activity has cross-reference “MetaCyc:RXN-24222”
4’-phosphopantetheine phosphatase activity has cross-reference “RHEA:68328”
4’-phosphopantetheine phosphatase activity has exact synonym “pantetheine-4’-phosphate phosphatase activity”
4’-phosphopantetheine phosphatase activity has exact synonym “phosphopantetheine phosphatase activity”
4’-phosphopantetheine phosphatase activity has_obo_namespace “molecular_function”
4’-phosphopantetheine phosphatase activity id “GO:7770095”
4’-phosphopantetheine phosphatase activity exactMatch RXN-24222
4’-phosphopantetheine phosphatase activity exactMatch 3.1.3.110
4’-phosphopantetheine phosphatase activity exactMatch 68328
4’-phosphopantetheine phosphatase activity definition “Catalysis of the reaction: (R)-4’-phosphopantetheine + H2O = (R)-pantetheine + phosphate.”
- has cross-reference “PMID:35896750”
- has cross-reference “PMID:27322068”
- has cross-reference “PMID:18678912”
- has cross-reference “RHEA:68328”
- has cross-reference “EC:3.1.3.110”
4’-phosphopantetheine phosphatase activity label “4’-phosphopantetheine phosphatase activity”
4’-phosphopantetheine phosphatase activity SubClassOf phosphatase activity
4’-phosphopantetheine phosphatase activity SubClassOf has participant some water
4’-phosphopantetheine phosphatase activity SubClassOf has participant some pantetheine
4’-phosphopantetheine phosphatase activity SubClassOf has participant some hydrogenphosphate
4’-phosphopantetheine phosphatase activity SubClassOf has participant some D-pantetheine 4’-phosphate(2-)

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex `http://purl.obolibrary.org/obo/GO_0043540`

Removed

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex SubClassOf capable of part of some obsolete canonical glycolysis

Added

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex SubClassOf capable of part of some glycolysis

6-phosphofructokinase activity `http://purl.obolibrary.org/obo/GO_0003872`

Removed

6-phosphofructokinase activity SubClassOf part of some obsolete glycolytic process through fructose-6-phosphate

Added

6-phosphofructokinase activity SubClassOf part of some glycolysis

7-methylguanosine cap hypermethylation `http://purl.obolibrary.org/obo/GO_0036261`

Removed

7-methylguanosine cap hypermethylation definition “Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2’ position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.”
- has cross-reference “GOC:rl”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:krc”
- has cross-reference “PMID:18775984”
- has cross-reference “PMID:11983179”
- has cross-reference “GOC:bf”
- has cross-reference “GOC:BHF”

Added

7-methylguanosine cap hypermethylation term tracker item “https://github.com/geneontology/go-ontology/issues/27628”^^anyURI
7-methylguanosine cap hypermethylation definition “Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the N2 position of the guanine base to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.”
- has cross-reference “GOC:rl”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:krc”
- has cross-reference “PMID:18775984”
- has cross-reference “PMID:11983179”
- has cross-reference “PMID:15590684”
- has cross-reference “GOC:bf”
- has cross-reference “GOC:BHF”

ABC-type cadmium transporter activity `http://purl.obolibrary.org/obo/GO_0015434`

Added

ABC-type cadmium transporter activity term tracker item “https://github.com/geneontology/go-ontology/issues/20824”^^anyURI
ABC-type cadmium transporter activity broadMatch 12132
ABC-type cadmium transporter activity comment “Note that RHEA:12132 represents both the ABC and the P-type cadmium transporters.”

ABC-type protein transporter activity `http://purl.obolibrary.org/obo/GO_0015462`

Removed

ABC-type protein transporter activity definition “Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in).”
- has cross-reference “GOC:jl”

Added

ABC-type protein transporter activity term tracker item “https://github.com/geneontology/go-ontology/issues/32395”^^anyURI
ABC-type protein transporter activity definition “Enables the transfer of a protein from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in).”
- has cross-reference “GOC:jl”

ATG2-ATG18 complex `http://purl.obolibrary.org/obo/GO_0062079`

Removed

ATG2-ATG18 complex SubClassOf part of some obsolete phagophore assembly site membrane

Added

ATG2-ATG18 complex term tracker item “https://github.com/geneontology/go-ontology/issues/29437”^^anyURI
ATG2-ATG18 complex SubClassOf part of some phagophore membrane

ATP-dependent folded protein transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_7770098`

Added

Class: ATP-dependent folded protein transmembrane transporter activity
ATP-dependent folded protein transmembrane transporter activity term tracker item “https://github.com/geneontology/go-ontology/issues/32394”^^anyURI
ATP-dependent folded protein transmembrane transporter activity created by “ai4c-agent”
ATP-dependent folded protein transmembrane transporter activity creation date “2026-08-04T00:40:41Z”
ATP-dependent folded protein transmembrane transporter activity has exact synonym “ATPase-coupled folded protein transmembrane transporter activity”
ATP-dependent folded protein transmembrane transporter activity has exact synonym “folded protein-transporting ATPase activity”
ATP-dependent folded protein transmembrane transporter activity has_obo_namespace “molecular_function”
ATP-dependent folded protein transmembrane transporter activity has_related_synonym “folded protein translocase activity”
ATP-dependent folded protein transmembrane transporter activity id “GO:7770098”
ATP-dependent folded protein transmembrane transporter activity definition “Enables the transfer of a protein in its native, folded conformation from one side of a membrane to the other, coupled to the hydrolysis of ATP and without unfolding of the substrate, according to the reaction: ATP + H2O + protein[side 1] = ADP + phosphate + protein[side 2].”
- has cross-reference “PMID:32042153”
- has cross-reference “PMID:40410623”
- has cross-reference “PMID:31988523”
ATP-dependent folded protein transmembrane transporter activity comment “This activity is exemplified by the mitochondrial inner membrane AAA-ATPase Bcs1 (BCS1L in mammals), which translocates the folded, 2Fe-2S-loaded Rieske iron-sulfur protein from the mitochondrial matrix across the inner membrane during respiratory complex III assembly. Unlike most AAA+ protein translocases, the substrate is not threaded through an axial pore in an extended conformation; in Bcs1 it passes between two aqueous vestibules separated by a seal, in an airlock-like mechanism that preserves the membrane permeability barrier. Do not use this term for the separable channel and motor activities of multi-subunit translocases; for those, consider ‘transmembrane protein transporter activity ; GO:0008320’ and ‘protein translocation chaperone activity ; GO:0140388’.”
ATP-dependent folded protein transmembrane transporter activity label “ATP-dependent folded protein transmembrane transporter activity”
ATP-dependent folded protein transmembrane transporter activity SubClassOf protein-transporting ATPase activity

ATP-dependent protein-RNA complex displacement activity `http://purl.obolibrary.org/obo/GO_7770106`

Added

Class: ATP-dependent protein-RNA complex displacement activity
ATP-dependent protein-RNA complex displacement activity term tracker item “https://github.com/geneontology/go-ontology/issues/32232”^^anyURI
ATP-dependent protein-RNA complex displacement activity created by “ai4c-agent”
ATP-dependent protein-RNA complex displacement activity creation date “2026-08-07T16:59:22Z”
ATP-dependent protein-RNA complex displacement activity has_broad_synonym “RNP remodeling ATPase activity”
ATP-dependent protein-RNA complex displacement activity has exact synonym “ATP-dependent RNA-protein complex displacement activity”
ATP-dependent protein-RNA complex displacement activity has exact synonym “RNPase activity”
ATP-dependent protein-RNA complex displacement activity has_obo_namespace “molecular_function”
ATP-dependent protein-RNA complex displacement activity id “GO:7770106”
ATP-dependent protein-RNA complex displacement activity definition “An activity that displaces a protein or protein complex from RNA in a ribonucleoprotein (RNP) complex, driven by ATP hydrolysis.”
- has cross-reference “PMID:11175897”
- has cross-reference “PMID:39122693”
- has cross-reference “PMID:15118161”
- has cross-reference “PMID:28864812”
ATP-dependent protein-RNA complex displacement activity comment “Analogous to the DNA-side activity GO:0061995 (ATP-dependent protein-DNA complex displacement activity). The community-used term "RNPase" refers to this activity.”
ATP-dependent protein-RNA complex displacement activity label “ATP-dependent protein-RNA complex displacement activity”
ATP-dependent protein-RNA complex displacement activity SubClassOf ATP-dependent activity, acting on RNA

ATPase-coupled L-glutamate transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0102013`

Removed

ATPase-coupled L-glutamate transmembrane transporter activity label “ATPase-coupled L-glutamate tranmembrane transporter activity”

Added

ATPase-coupled L-glutamate transmembrane transporter activity label “ATPase-coupled L-glutamate transmembrane transporter activity”

Atg9-containing vesicle `http://purl.obolibrary.org/obo/GO_7770115`

Added

Class: Atg9-containing vesicle
Atg9-containing vesicle term tracker item “https://github.com/geneontology/go-ontology/issues/29437”^^anyURI
Atg9-containing vesicle created by “ai4c-agent”
Atg9-containing vesicle creation date “2026-08-20T23:57:41Z”
Atg9-containing vesicle has exact synonym “Atg9 vesicle”
Atg9-containing vesicle has narrow synonym “ATG9A vesicle”
Atg9-containing vesicle has_obo_namespace “cellular_component”
Atg9-containing vesicle id “GO:7770115”
Atg9-containing vesicle has_related_synonym “Atg9-containing compartment”
- has cross-reference “PMID:20855505”
Atg9-containing vesicle definition “A small, single-membrane cytoplasmic vesicle that carries the transmembrane autophagy protein Atg9 (ATG9A in mammals). Vesicles of this type are derived from the Golgi apparatus and from endosomal compartments, and can be delivered to the phagophore assembly site, where they contribute membrane to the nascent phagophore.”
- has cross-reference “PMID:32883836”
- has cross-reference “PMID:24034251”
- has cross-reference “PMID:20855505”
- has cross-reference “PMID:22826123”
Atg9-containing vesicle comment “In Saccharomyces cerevisiae these vesicles are 30-60 nm in diameter and approximately three are consumed per autophagosome. In mammals ATG9A vesicles traffic via the trans-Golgi network and recycling endosomes, and a substantial part of the pool is not engaged in autophagosome formation at any given time. Use this term for the vesicle itself, at any stage of its itinerary. Membrane that has been incorporated into the phagophore is phagophore membrane (GO:7770114) rather than a vesicle. The Atg9-containing compartment/reservoir described by Mari et al. (PMID:20855505) is a cluster of these vesicles and tubules rather than a single vesicle; use this term for the individual vesicles that make up such clusters.”
Atg9-containing vesicle label “Atg9-containing vesicle”
Atg9-containing vesicle SubClassOf cytoplasmic vesicle
Atg9-containing vesicle SubClassOf in taxon some cellular organisms
Atg9-containing vesicle SubClassOf capable of part of some autophagosome assembly

B cell cytokine production `http://purl.obolibrary.org/obo/GO_0002368`

Removed

B cell cytokine production EquivalentTo cytokine production and (process has causal agent some B cell)

Added

B cell cytokine production EquivalentTo cytokine production and (occurs in some B cell)
B cell cytokine production SubClassOf occurs in some B cell

B cell mediated immunity `http://purl.obolibrary.org/obo/GO_0019724`

Removed

B cell mediated immunity EquivalentTo immune system process and (process has causal agent some B cell)

B cell tolerance induction in mucosal-associated lymphoid tissue `http://purl.obolibrary.org/obo/GO_0002402`

Removed

B cell tolerance induction in mucosal-associated lymphoid tissue definition “Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells.”
- has cross-reference “ISBN:0781735149”
- has cross-reference “GOC:jal”
B cell tolerance induction in mucosal-associated lymphoid tissue EquivalentTo tolerance induction in mucosal-associated lymphoid tissue and (process has causal agent some B cell)

Added

B cell tolerance induction in mucosal-associated lymphoid tissue term tracker item “https://github.com/geneontology/go-ontology/issues/20574”^^anyURI
B cell tolerance induction in mucosal-associated lymphoid tissue definition “Tolerance induction taking place in a B cell within the mucosal-associated lymphoid tissue (MALT).”
- has cross-reference “ISBN:0781735149”
- has cross-reference “GOC:jal”
B cell tolerance induction in mucosal-associated lymphoid tissue EquivalentTo tolerance induction in mucosal-associated lymphoid tissue and (occurs in some B cell)

B-type glycerophospholipase activity `http://purl.obolibrary.org/obo/GO_0102545`

Removed

B-type glycerophospholipase activity definition “A glycerophospholipase activity that cleaves both fatty acisd attached to the sn-1 and the sn-2 position of the glycerol group of a glycerophospholipid. Substrates include phosphatidylcholine and phosphatidylethanolamine.”
- has cross-reference “PMID:30109646”

Added

B-type glycerophospholipase activity definition “A glycerophospholipase activity that cleaves both fatty acids attached to the sn-1 and the sn-2 position of the glycerol group of a glycerophospholipid. Substrates include phosphatidylcholine and phosphatidylethanolamine.”
- has cross-reference “PMID:30109646”

CD4-positive, alpha-beta T cell cytokine production `http://purl.obolibrary.org/obo/GO_0035743`

Removed

CD4-positive, alpha-beta T cell cytokine production EquivalentTo cytokine production and (process has causal agent some CD4-positive, alpha-beta T cell)
CD4-positive, alpha-beta T cell cytokine production SubClassOf process has causal agent some CD4-positive, alpha-beta T cell

Added

CD4-positive, alpha-beta T cell cytokine production EquivalentTo cytokine production and (occurs in some CD4-positive, alpha-beta T cell)
CD4-positive, alpha-beta T cell cytokine production SubClassOf occurs in some CD4-positive, alpha-beta T cell

D-glucosamine biosynthetic process `http://purl.obolibrary.org/obo/GO_0006042`

Removed

D-glucosamine biosynthetic process SubClassOf obsolete D-glucosamine metabolic process

D-glucosamine catabolic process `http://purl.obolibrary.org/obo/GO_0006043`

Removed

D-glucosamine catabolic process SubClassOf obsolete D-glucosamine metabolic process

D-lactate dehydrogenase (FAD) activity `http://purl.obolibrary.org/obo/GO_0140170`

Added

D-lactate dehydrogenase (FAD) activity term tracker item “https://github.com/geneontology/go-ontology/issues/32501”^^anyURI
D-lactate dehydrogenase (FAD) activity SubClassOf (2R)-2-hydroxycarboxylate dehydrogenase (FAD) activity

D-sorbitol biosynthetic process `http://purl.obolibrary.org/obo/GO_0006061`

Added

D-sorbitol biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/32269”^^anyURI
D-sorbitol biosynthetic process never in taxon Schizosaccharomyces
D-sorbitol biosynthetic process SubClassOf not (in taxon some Schizosaccharomyces)

D-xylose reductase (NADPH) activity `http://purl.obolibrary.org/obo/GO_0032866`

Added

D-xylose reductase (NADPH) activity term tracker item “https://github.com/geneontology/go-ontology/issues/27881”^^anyURI
D-xylose reductase (NADPH) activity SubClassOf alcohol dehydrogenase (NADP+) activity

DNA recombinase auxiliary factor complex `http://purl.obolibrary.org/obo/GO_0120231`

Removed

DNA recombinase auxiliary factor complex definition “A protein complex that binds to a recombinase and incrseases its activity.”
- has cross-reference “PMID:32414915”

Added

DNA recombinase auxiliary factor complex definition “A protein complex that binds to a recombinase and increases its activity.”
- has cross-reference “PMID:32414915”

ER lumen protein retrieval receptor activity `http://purl.obolibrary.org/obo/GO_0046923`

Removed

ER lumen protein retrieval receptor activity has exact synonym “endoplasmic reticulum retention sequence binding”
ER lumen protein retrieval receptor activity has narrow synonym “DDEL signal sequence receptor activity”
ER lumen protein retrieval receptor activity has narrow synonym “ER retention sequence binding”
ER lumen protein retrieval receptor activity has narrow synonym “HDEL signal sequence receptor activity”
ER lumen protein retrieval receptor activity has narrow synonym “KDEL signal sequence receptor activity”
ER lumen protein retrieval receptor activity definition “Binding to an endoplasmic reticulum (ER) retention sequence, a short stretch of amino acids found in a protein that acts as a signal to retain the protein within the ER.”
- has cross-reference “GOC:ai”
ER lumen protein retrieval receptor activity SubClassOf signal sequence receptor activity

Added

ER lumen protein retrieval receptor activity term tracker item “https://github.com/geneontology/go-ontology/issues/32307”^^anyURI
ER lumen protein retrieval receptor activity has_related_synonym “DDEL signal sequence receptor activity”
ER lumen protein retrieval receptor activity has_related_synonym “ER retention sequence binding”
ER lumen protein retrieval receptor activity has_related_synonym “HDEL signal sequence receptor activity”
ER lumen protein retrieval receptor activity has_related_synonym “KDEL signal sequence receptor activity”
ER lumen protein retrieval receptor activity has_related_synonym “endoplasmic reticulum retention sequence binding”
ER lumen protein retrieval receptor activity definition “Binding to a C-terminal ER retrieval signal, such as KDEL, HDEL or DDEL, present on soluble lumenal proteins that have escaped from the endoplasmic reticulum (ER) to the Golgi, and mediating their return to the ER.”
- has cross-reference “PMID:33037041”
ER lumen protein retrieval receptor activity SubClassOf cargo receptor activity
ER lumen protein retrieval receptor activity SubClassOf part of some retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

ER membrane protein retrieval receptor activity `http://purl.obolibrary.org/obo/GO_7770094`

Added

Class: ER membrane protein retrieval receptor activity
ER membrane protein retrieval receptor activity term tracker item “https://github.com/geneontology/go-ontology/issues/32307”^^anyURI
ER membrane protein retrieval receptor activity created by “ai4c-agent”
ER membrane protein retrieval receptor activity creation date “2026-07-29T19:05:05Z”
ER membrane protein retrieval receptor activity has exact synonym “endoplasmic reticulum membrane protein retrieval receptor activity”
ER membrane protein retrieval receptor activity has narrow synonym “KKXX motif binding”
ER membrane protein retrieval receptor activity has narrow synonym “KKXX signal receptor activity”
ER membrane protein retrieval receptor activity has narrow synonym “dilysine motif binding”
ER membrane protein retrieval receptor activity has_obo_namespace “molecular_function”
ER membrane protein retrieval receptor activity id “GO:7770094”
ER membrane protein retrieval receptor activity definition “Binding to a retrieval signal, such as a C-terminal KKXX/KXKX-type dilysine motif or an exposed transmembrane domain determinant, present on integral membrane proteins that have escaped from the endoplasmic reticulum (ER) to the Golgi, and mediating their return to the ER.”
- has cross-reference “PMID:12972550”
ER membrane protein retrieval receptor activity label “ER membrane protein retrieval receptor activity”
ER membrane protein retrieval receptor activity SubClassOf cargo receptor activity
ER membrane protein retrieval receptor activity SubClassOf part of some retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

ER overload response `http://purl.obolibrary.org/obo/GO_0006983`

Added

ER overload response term tracker item “https://github.com/geneontology/go-ontology/issues/20914”^^anyURI
ER overload response SubClassOf part of some endoplasmic reticulum protein quality control

ERAD quality control pathway `http://purl.obolibrary.org/obo/GO_0036503`

Removed

ERAD quality control pathway definition “The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.”
- has cross-reference “PMID:20940304”
- has cross-reference “GOC:PARL”
- has cross-reference “PMID:21969857”
- has cross-reference “GOC:bf”
ERAD quality control pathway has exact synonym “protein degradation by ERAD”
- has cross-reference “GOC:bf”
ERAD quality control pathway has exact synonym “endoplasmic reticulum-associated degradation”
- has cross-reference “PMID:22535891”
ERAD quality control pathway label “ERAD pathway”
ERAD quality control pathway SubClassOf response to endoplasmic reticulum stress
ERAD quality control pathway SubClassOf response to chemical

Added

ERAD quality control pathway term tracker item “https://github.com/geneontology/go-ontology/issues/20914”^^anyURI
ERAD quality control pathway term tracker item “https://github.com/geneontology/go-ontology/issues/32527”^^anyURI
ERAD quality control pathway term tracker item “https://github.com/geneontology/go-ontology/issues/32532”^^anyURI
ERAD quality control pathway has_broad_synonym “ERAD pathway”
ERAD quality control pathway definition “The protein catabolic pathway which constitutively monitors and targets misfolded/aberrant endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.”
- has cross-reference “PMID:20940304”
- has cross-reference “GOC:PARL”
- has cross-reference “PMID:21969857”
- has cross-reference “GOC:bf”
ERAD quality control pathway has_broad_synonym “protein degradation by ERAD”
- has cross-reference “GOC:bf”
ERAD quality control pathway has_broad_synonym “endoplasmic reticulum-associated degradation”
- has cross-reference “PMID:22535891”
ERAD quality control pathway label “ERAD quality control pathway”
ERAD quality control pathway SubClassOf endoplasmic reticulum protein quality control

ESCRT III complex `http://purl.obolibrary.org/obo/GO_0000815`

Removed

ESCRT III complex definition “A complex with membrane scission activity that plays a major role in many processes where membranes are remodelled - including endosomal transport (vesicle budding), nuclear envelope organisation (membrane closure, mitotic bridge cleavage), and cytokinesis (abscission).”
- has cross-reference “PMID:17556548”
- has cross-reference “PMID:34449766”
- has cross-reference “PMID:32243490”
- has cross-reference “PMID:22361144”
- has cross-reference “PMID:28242692”
- has cross-reference “PMID:31132588”

Added

ESCRT III complex definition “A complex with membrane scission activity that plays a major role in many processes where membranes are remodelled - including endosomal transport (vesicle budding), nuclear envelope organization (membrane closure, mitotic bridge cleavage), and cytokinesis (abscission).”
- has cross-reference “PMID:17556548”
- has cross-reference “PMID:34449766”
- has cross-reference “PMID:32243490”
- has cross-reference “PMID:22361144”
- has cross-reference “PMID:28242692”
- has cross-reference “PMID:31132588”

FAD regeneration via ETF:ETFQO system `http://purl.obolibrary.org/obo/GO_7770096`

Added

Class: FAD regeneration via ETF:ETFQO system
FAD regeneration via ETF:ETFQO system term tracker item “https://github.com/geneontology/go-ontology/issues/32355”^^anyURI
FAD regeneration via ETF:ETFQO system created by “ai4c-agent”
FAD regeneration via ETF:ETFQO system creation date “2026-07-30T22:03:00Z”
FAD regeneration via ETF:ETFQO system has exact synonym “ETF-ETFQO system”
FAD regeneration via ETF:ETFQO system has exact synonym “FAD regeneration via ETF-ETFQO system”
FAD regeneration via ETF:ETFQO system has exact synonym “reoxidation of reduced electron transfer flavoprotein”
FAD regeneration via ETF:ETFQO system has_obo_namespace “biological_process”
FAD regeneration via ETF:ETFQO system id “GO:7770096”
FAD regeneration via ETF:ETFQO system definition “A metabolic process that transfers electrons produced by FAD-dependent dehydrogenases involved in amino acid and lipid catabolism to the electron transport chain. Electrons released during FADH2 oxidation are transferred by electron-transfer flavoprotein (ETF) to ETF-ubiquinone oxidoreductase (ETF-QO), which in turn transfers them to ubiquinone and then to complex III of the electron transport chain.”
- has cross-reference “PMID:33450351”
- has cross-reference “PMID:28808132”
FAD regeneration via ETF:ETFQO system comment “In eukaryotes, FAD regeneration via the ETF:ETFQO system occurs in the mitochondrion, with ETF in the matrix and ETF-QO in the inner membrane. Some bacteria and archaea have a similar system, so no taxon constraint applies to this term. This term covers the ETF/ETF-QO route specifically; do not use it for flavoprotein dehydrogenases that reduce the quinone pool directly without ETF (for example succinate dehydrogenase, see GO:0006121), or for reoxidation of flavin by molecular oxygen in peroxisomes or the endoplasmic reticulum.”
FAD regeneration via ETF:ETFQO system label “FAD regeneration via ETF:ETFQO system”
FAD regeneration via ETF:ETFQO system SubClassOf respiratory electron transport chain
FAD regeneration via ETF:ETFQO system SubClassOf FAD metabolic process
FAD regeneration via ETF:ETFQO system SubClassOf has primary output some FAD(3-)
FAD regeneration via ETF:ETFQO system SubClassOf has primary input some FADH2(2-)

FMN adenylyltransferase activity `http://purl.obolibrary.org/obo/GO_0003919`

Removed

FMN adenylyltransferase activity definition “Catalysis of the reaction: ATP + FMN = diphosphate + FAD.”
- has cross-reference “EC:2.7.7.2”
- has cross-reference “RHEA:17237”

Added

FMN adenylyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32345”^^anyURI
FMN adenylyltransferase activity definition “Catalysis of the reaction: FMN + ATP + H+ = FAD + diphosphate.”
- has cross-reference “RHEA:17237”

G-protein beta/gamma-subunit complex `http://purl.obolibrary.org/obo/GO_0031680`

Removed

G-protein beta/gamma-subunit complex definition “The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange.”
- has cross-reference “GOC:mah”

Added

G-protein beta/gamma-subunit complex definition “The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nucleotide exchange.”
- has cross-reference “GOC:mah”

GPI anchor remodeling `http://purl.obolibrary.org/obo/GO_0120574`

Removed

GPI anchor remodeling label “GPI anchor remodelling”

Added

GPI anchor remodeling label “GPI anchor remodeling”

Hrd1p ubiquitin ligase complex `http://purl.obolibrary.org/obo/GO_0000836`

Removed

Hrd1p ubiquitin ligase complex definition “A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78).”
- has cross-reference “PMID:16873066”
- has cross-reference “GOC:elh”
- has cross-reference “PMID:21454652”
- has cross-reference “GOC:bf”
- has cross-reference “PMID:16619026”

Added

Hrd1p ubiquitin ligase complex term tracker item “https://github.com/geneontology/go-ontology/issues/32529”^^anyURI
Hrd1p ubiquitin ligase complex definition “A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin).”
- has cross-reference “PMID:16873066”
- has cross-reference “GOC:elh”
- has cross-reference “PMID:21454652”
- has cross-reference “PMID:20100910”
- has cross-reference “GOC:bf”
- has cross-reference “PMID:16619026”

L-arabinose reductase (NADPH) activity `http://purl.obolibrary.org/obo/GO_0032867`

Added

L-arabinose reductase (NADPH) activity term tracker item “https://github.com/geneontology/go-ontology/issues/27881”^^anyURI
L-arabinose reductase (NADPH) activity SubClassOf alcohol dehydrogenase (NADP+) activity

L-malate dehydrogenase (NAD+) activity `http://purl.obolibrary.org/obo/GO_0030060`

Removed

L-malate dehydrogenase (NAD+) activity SubClassOf oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Added

L-malate dehydrogenase (NAD+) activity term tracker item “https://github.com/geneontology/go-ontology/issues/32501”^^anyURI
L-malate dehydrogenase (NAD+) activity SubClassOf L-2-hydroxycarboxylate dehydrogenase (NAD+) activity

L-methionine cycle `http://purl.obolibrary.org/obo/GO_0033353`

Removed

L-methionine cycle definition “A cyclic series of interconversions involving S-adenosyl-L-homocysteine, L-homocysteine, L-methionine and S-adenosyl-L-methionine (SAM). Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of L-methionine.”
- has cross-reference “PMID:31950558”
- has cross-reference “PMID:39394448”

Added

L-methionine cycle term tracker item “https://github.com/geneontology/go-ontology/issues/32362”^^anyURI
L-methionine cycle definition “A cyclic series of interconversions involving S-adenosyl-L-homocysteine, L-homocysteine, L-methionine and S-adenosyl-L-methionine (SAM). Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of L-methionine.”
- has cross-reference “PMID:32961717”
- has cross-reference “PMID:31950558”
- has cross-reference “PMID:39394448”
L-methionine cycle SubClassOf one-carbon metabolic process

L-phenylalanine oxidase activity `http://purl.obolibrary.org/obo/GO_0106329`

Removed

L-phenylalanine oxidase activity label “L-phenylalaine oxidase activity”

Added

L-phenylalanine oxidase activity label “L-phenylalanine oxidase activity”

N-acetylglucosamine biosynthetic process `http://purl.obolibrary.org/obo/GO_0006045`

Removed

N-acetylglucosamine biosynthetic process SubClassOf obsolete N-acetylglucosamine metabolic process

N-acetylglucosamine catabolic process `http://purl.obolibrary.org/obo/GO_0006046`

Removed

N-acetylglucosamine catabolic process SubClassOf obsolete N-acetylglucosamine metabolic process

N-acetylmannosamine biosynthetic process `http://purl.obolibrary.org/obo/GO_0006052`

Removed

N-acetylmannosamine biosynthetic process SubClassOf obsolete N-acetylmannosamine metabolic process

N-acetylmannosamine catabolic process `http://purl.obolibrary.org/obo/GO_0006053`

Removed

N-acetylmannosamine catabolic process SubClassOf obsolete N-acetylmannosamine metabolic process

N-acetylneuraminate biosynthetic process `http://purl.obolibrary.org/obo/GO_0046380`

Removed

N-acetylneuraminate biosynthetic process SubClassOf obsolete N-acetylneuraminate metabolic process

N-acetylneuraminate catabolic process `http://purl.obolibrary.org/obo/GO_0019262`

Removed

N-acetylneuraminate catabolic process SubClassOf obsolete N-acetylneuraminate metabolic process

NAD+ nucleosidase activity, cyclic ADP-ribose generating `http://purl.obolibrary.org/obo/GO_0061809`

Removed

Added

NAD+ nucleosidase activity, cyclic ADP-ribose generating term tracker item “https://github.com/geneontology/go-ontology/issues/32457”^^anyURI
NAD+ nucleosidase activity, cyclic ADP-ribose generating SubClassOf has part some cyclic ADP-ribose hydrolase activity

NAD+-protein-arginine ADP-ribosyltransferase activity `http://purl.obolibrary.org/obo/GO_0106274`

Added

NAD+-protein-arginine ADP-ribosyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32503”^^anyURI
NAD+-protein-arginine ADP-ribosyltransferase activity has cross-reference “RHEA:18077”
NAD+-protein-arginine ADP-ribosyltransferase activity narrowMatch 18077

NAD-cap decapping `http://purl.obolibrary.org/obo/GO_0110155`

Removed

NAD-cap decapping definition “Cleavage of the 5’-NAD-cap of an RNA. The NAD-cap is present at the 5’-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes.”
- has cross-reference “GOC:sp”
- has cross-reference “PMID:31101919”
- has cross-reference “PMID:28283058”
- has cross-reference “PMID:25533955”

Added

NAD-cap decapping definition “Cleavage of the 5’-NAD-cap of an RNA. The NAD-cap is present at the 5’-end of some RNAs in both bacteria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes.”
- has cross-reference “GOC:sp”
- has cross-reference “PMID:31101919”
- has cross-reference “PMID:28283058”
- has cross-reference “PMID:25533955”

NADH-dependent peroxiredoxin activity `http://purl.obolibrary.org/obo/GO_0102039`

Removed

NADH-dependent peroxiredoxin activity SubClassOf peroxiredoxin activity

Added

NADH-dependent peroxiredoxin activity term tracker item “https://github.com/geneontology/go-ontology/issues/32372”^^anyURI
NADH-dependent peroxiredoxin activity SubClassOf peroxidase activity

NADP+ biosynthetic process `http://purl.obolibrary.org/obo/GO_0006741`

Removed

NADP+ biosynthetic process conformsTo biosynthetic_process.yaml

NAGS/NAGK complex `http://purl.obolibrary.org/obo/GO_0106098`

Removed

NAGS/NAGK complex definition “A protein complex that acts both as N-acetylglutamate synthase (NAGS) catalysing the production of N-Acetylglutamate from glutamate and acetyl-CoA, and as N-acetylglutamate kinase (NAGK) catalysing the reaction ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate.”
- has cross-reference “GOC:lnp”
- has cross-reference “PMID:11553611”

Added

NAGS/NAGK complex definition “A protein complex that acts both as N-acetylglutamate synthase (NAGS) catalyzing the production of N-Acetylglutamate from glutamate and acetyl-CoA, and as N-acetylglutamate kinase (NAGK) catalyzing the reaction ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate.”
- has cross-reference “GOC:lnp”
- has cross-reference “PMID:11553611”

NMDA glutamate receptor activity `http://purl.obolibrary.org/obo/GO_0004972`

Removed

NMDA glutamate receptor activity definition “A cation channel that opens in response to binding by extracellular glutmate, but only if glycine or D-serine is also bound and the membrane is depolarized. Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages.”
- has cross-reference “GOC:mah”
- has cross-reference “PMID:7790891”
- has cross-reference “PMID:10049997”

Added

NMDA glutamate receptor activity definition “A cation channel that opens in response to binding by extracellular glutamate, but only if glycine or D-serine is also bound and the membrane is depolarized. Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages.”
- has cross-reference “GOC:mah”
- has cross-reference “PMID:7790891”
- has cross-reference “PMID:10049997”

P-type cadmium transporter activity `http://purl.obolibrary.org/obo/GO_0008551`

Removed

P-type cadmium transporter activity has cross-reference “RHEA:12132”
P-type cadmium transporter activity exactMatch 12132
P-type cadmium transporter activity SubClassOf has participant some water
P-type cadmium transporter activity SubClassOf has participant some hydron
P-type cadmium transporter activity SubClassOf has participant some ATP(4-)
P-type cadmium transporter activity SubClassOf has participant some hydrogenphosphate
P-type cadmium transporter activity SubClassOf has participant some ADP(3-)
P-type cadmium transporter activity SubClassOf has participant some cadmium(2+)

Added

P-type cadmium transporter activity term tracker item “https://github.com/geneontology/go-ontology/issues/20824”^^anyURI
P-type cadmium transporter activity broadMatch 12132
P-type cadmium transporter activity comment “Note that RHEA:12132 represents both the ABC and the P-type cadmium transporters.”

R-loop processing `http://purl.obolibrary.org/obo/GO_0062176`

Removed

R-loop processing definition “A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability.”
- has cross-reference “PMID:27252122”
- has cross-reference “PMID:28790157”
- has cross-reference “PMID:33986538”

Added

R-loop processing definition “A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisting of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability.”
- has cross-reference “PMID:27252122”
- has cross-reference “PMID:28790157”
- has cross-reference “PMID:33986538”

RADAR pathway `http://purl.obolibrary.org/obo/GO_0170074`

Added

RADAR pathway SubClassOf peroxisomal protein quality control

RNA (adenine-N6)-methyltransferase activity `http://purl.obolibrary.org/obo/GO_7770107`

Added

Class: RNA (adenine-N6)-methyltransferase activity
RNA (adenine-N6)-methyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/27200”^^anyURI
RNA (adenine-N6)-methyltransferase activity created by “ai4c-agent”
RNA (adenine-N6)-methyltransferase activity creation date “2026-08-07T23:44:01Z”
RNA (adenine-N6)-methyltransferase activity has exact synonym “RNA (N6-adenosine)-methyltransferase activity”
RNA (adenine-N6)-methyltransferase activity has exact synonym “RNA m6A methyltransferase activity”
RNA (adenine-N6)-methyltransferase activity has_obo_namespace “molecular_function”
RNA (adenine-N6)-methyltransferase activity id “GO:7770107”
RNA (adenine-N6)-methyltransferase activity definition “Catalysis of the reaction: an adenosine in RNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in RNA + S-adenosyl-L-homocysteine + H+.”
- has cross-reference “PMID:36736310”
- has cross-reference “PMID:34023900”
RNA (adenine-N6)-methyltransferase activity label “RNA (adenine-N6)-methyltransferase activity”
RNA (adenine-N6)-methyltransferase activity SubClassOf N-methyltransferase activity
RNA (adenine-N6)-methyltransferase activity SubClassOf RNA methyltransferase activity

RQC-specific ribosome subunit dissociation `http://purl.obolibrary.org/obo/GO_7770113`

Added

Class: RQC-specific ribosome subunit dissociation
RQC-specific ribosome subunit dissociation term tracker item “https://github.com/geneontology/go-ontology/issues/32478”^^anyURI
RQC-specific ribosome subunit dissociation conformsTo involved_in_x_y.yaml
RQC-specific ribosome subunit dissociation created by “ai4c-agent”
RQC-specific ribosome subunit dissociation creation date “2026-08-18T18:06:47Z”
RQC-specific ribosome subunit dissociation has exact synonym “ribosome disassembly involved in ribosome-associated quality control”
RQC-specific ribosome subunit dissociation has narrow synonym “ASCC-dependent ribosome subunit dissociation”
RQC-specific ribosome subunit dissociation has narrow synonym “RQT-dependent ribosome subunit dissociation”
RQC-specific ribosome subunit dissociation has_obo_namespace “biological_process”
RQC-specific ribosome subunit dissociation id “GO:7770113”
RQC-specific ribosome subunit dissociation definition “The disaggregation of a stalled ribosome into its constituent large and small ribosomal subunits as part of ribosome-associated quality control (RQC), releasing the large subunit with the incomplete nascent polypeptide chain still attached via peptidyl-tRNA for downstream RQC processing.”
- has cross-reference “PMID:32203490”
- has cross-reference “PMID:32579943”
- has cross-reference “PMID:35452614”
RQC-specific ribosome subunit dissociation comment “In eukaryotes, this step is carried out by the yeast RQT complex (Rqt2/Slh1, Rqt3/Cue3, Rqt4) or the metazoan ASCC complex, acting on Hel2/ZNF598-ubiquitinated collided ribosomes. In bacteria, MutS2 splits stalled collided ribosomes; this term is not restricted to eukaryotes.”
RQC-specific ribosome subunit dissociation label “RQC-specific ribosome subunit dissociation”
RQC-specific ribosome subunit dissociation EquivalentTo ribosome disassembly and (part of some ribosome-associated quality control)
RQC-specific ribosome subunit dissociation SubClassOf ribosome disassembly
RQC-specific ribosome subunit dissociation SubClassOf part of some ribosome-associated quality control

RQC-trigger complex `http://purl.obolibrary.org/obo/GO_0180022`

Removed

RQC-trigger complex definition “A ribosome disassembly complex which dissociates stalled ribsome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (human TRIP4). The human complex has an additional component protein ASCC1 and can act as a transcriptional coactivator by interacting with transcription factors such as NF-kappa B.”
- has cross-reference “PMID:32099016”
- has cross-reference “PMID:28757607”
- has cross-reference “PMID:12077347”

Added

RQC-trigger complex definition “A ribosome disassembly complex which dissociates stalled ribosome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (human TRIP4). The human complex has an additional component protein ASCC1 and can act as a transcriptional coactivator by interacting with transcription factors such as NF-kappa B.”
- has cross-reference “PMID:32099016”
- has cross-reference “PMID:28757607”
- has cross-reference “PMID:12077347”

S-methylmethionine cycle `http://purl.obolibrary.org/obo/GO_0033528`

Removed

S-methylmethionine cycle definition “A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level.”
- has cross-reference “MetaCyc:PWY-5441”
- has cross-reference “GOC:mah”

Added

S-methylmethionine cycle term tracker item “https://github.com/geneontology/go-ontology/issues/32362”^^anyURI
S-methylmethionine cycle definition “A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of S-adenosylmethionine back to free L-methionine, and may serve regulate the cellular adenosylmethionine level.”
- has cross-reference “MetaCyc:PWY-5441”
- has cross-reference “GOC:mah”
- has cross-reference “PMID:11337394”
S-methylmethionine cycle SubClassOf one-carbon metabolic process
S-methylmethionine cycle SubClassOf in taxon some Viridiplantae

Sca1 Ras guanyl-nucleotide exchange factor complex `http://purl.obolibrary.org/obo/GO_0170078`

Added

Class: Sca1 Ras guanyl-nucleotide exchange factor complex
Sca1 Ras guanyl-nucleotide exchange factor complex term tracker item “https://github.com/geneontology/go-ontology/issues/32432”^^anyURI
Sca1 Ras guanyl-nucleotide exchange factor complex created by “ew”
Sca1 Ras guanyl-nucleotide exchange factor complex creation date “2026-08-11T17:42:26Z”
Sca1 Ras guanyl-nucleotide exchange factor complex has_broad_synonym “Sca1 RasGEF complex”
Sca1 Ras guanyl-nucleotide exchange factor complex has_broad_synonym “Sca1 signaling complex”
Sca1 Ras guanyl-nucleotide exchange factor complex has_broad_synonym “Sca1-Aimless signaling complex”
Sca1 Ras guanyl-nucleotide exchange factor complex has_broad_synonym “Sca1-associated Ras guanyl-nucleotide exchange factor complex”
Sca1 Ras guanyl-nucleotide exchange factor complex has_obo_namespace “cellular_component”
Sca1 Ras guanyl-nucleotide exchange factor complex id “GO:0170078”
Sca1 Ras guanyl-nucleotide exchange factor complex definition “A protein complex found in Dictyostelium, containing the scaffold protein Sca1, the Ras guanine nucleotide exchange factors Aimless (RasGEFA) and RasGEFH, and PP2A components, which promotes RasC activation during chemotaxis.”
- has cross-reference “PMID:20493808”
Sca1 Ras guanyl-nucleotide exchange factor complex label “Sca1 Ras guanyl-nucleotide exchange factor complex”
Sca1 Ras guanyl-nucleotide exchange factor complex SubClassOf Ras guanyl-nucleotide exchange factor complex
Sca1 Ras guanyl-nucleotide exchange factor complex SubClassOf in taxon some Dictyostelia

Sec body `http://purl.obolibrary.org/obo/GO_7770092`

Added

Class: Sec body
Sec body term tracker item “https://github.com/geneontology/go-ontology/issues/32313”^^anyURI
Sec body created by “ai4c-agent”
Sec body creation date “2026-07-28T23:40:49Z”
Sec body has exact synonym “sec-body”
Sec body has_obo_namespace “cellular_component”
Sec body id “GO:7770092”
Sec body definition “A condensate that forms reversibly in the cytoplasm under stress, notably amino acid starvation or salt stress, by coalescence of endoplasmic reticulum exit site (ERES) components including the scaffold protein Sec16 and COPII coat subunits. Sec bodies form through liquid-liquid phase separation and act as a protective reservoir for ERES components, permitting reversible shutdown of the early secretory pathway and promoting cell survival during stress.”
- has cross-reference “PMID:31152627”
- has cross-reference “PMID:25386913”
- has cross-reference “PMID:36325988”
Sec body comment “A Sec body forms from components of an endoplasmic reticulum exit site (GO:0070971), which is progressively depleted as the Sec body grows; a Sec body is a distinct structure and is not part of an ER exit site.”
Sec body label “Sec body”
Sec body SubClassOf intracellular membraneless organelle
Sec body SubClassOf part of some cytoplasm
Sec body SubClassOf in taxon some cellular organisms

Sec body assembly `http://purl.obolibrary.org/obo/GO_7770093`

Added

Class: Sec body assembly
Sec body assembly term tracker item “https://github.com/geneontology/go-ontology/issues/32314”^^anyURI
Sec body assembly conformsTo cc_assembly.yaml
Sec body assembly created by “ai4c-agent”
Sec body assembly creation date “2026-07-28T23:40:49Z”
Sec body assembly has exact synonym “Sec body formation”
Sec body assembly has exact synonym “sec-body assembly”
Sec body assembly has_obo_namespace “biological_process”
Sec body assembly id “GO:7770093”
Sec body assembly definition “The aggregation, arrangement and bonding together of a set of components to form a Sec body.”
- has cross-reference “PMID:27874829”
- has cross-reference “PMID:25386913”
Sec body assembly label “Sec body assembly”
Sec body assembly EquivalentTo cellular component assembly and (results in assembly of some Sec body)
Sec body assembly SubClassOf membraneless organelle assembly
Sec body assembly SubClassOf in taxon some cellular organisms
Sec body assembly SubClassOf results in assembly of some Sec body

T cell cytokine production `http://purl.obolibrary.org/obo/GO_0002369`

Removed

T cell cytokine production EquivalentTo cytokine production and (process has causal agent some T cell)

Added

T cell cytokine production EquivalentTo cytokine production and (occurs in some T cell)
T cell cytokine production SubClassOf occurs in some T cell

T cell mediated cytotoxicity `http://purl.obolibrary.org/obo/GO_0001913`

Removed

T cell mediated cytotoxicity EquivalentTo cell killing and (process has causal agent some T cell)

T cell mediated immune response to tumor cell `http://purl.obolibrary.org/obo/GO_0002424`

Removed

T cell mediated immune response to tumor cell EquivalentTo immune response to tumor cell and (process has causal agent some T cell)

T cell mediated immunity `http://purl.obolibrary.org/obo/GO_0002456`

Removed

T cell mediated immunity EquivalentTo immune system process and (process has causal agent some T cell)

T cell tolerance induction in mucosal-associated lymphoid tissue `http://purl.obolibrary.org/obo/GO_0002403`

Removed

T cell tolerance induction in mucosal-associated lymphoid tissue definition “Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells.”
- has cross-reference “ISBN:0781735149”
- has cross-reference “PMID:16551263”
- has cross-reference “GOC:jal”
T cell tolerance induction in mucosal-associated lymphoid tissue EquivalentTo tolerance induction in mucosal-associated lymphoid tissue and (process has causal agent some T cell)

Added

T cell tolerance induction in mucosal-associated lymphoid tissue term tracker item “https://github.com/geneontology/go-ontology/issues/20574”^^anyURI
T cell tolerance induction in mucosal-associated lymphoid tissue definition “Tolerance induction taking place in a T cell within the mucosal-associated lymphoid tissue (MALT).”
- has cross-reference “ISBN:0781735149”
- has cross-reference “PMID:16551263”
- has cross-reference “GOC:jal”
T cell tolerance induction in mucosal-associated lymphoid tissue EquivalentTo tolerance induction in mucosal-associated lymphoid tissue and (occurs in some T cell)

T cell tolerance induction to tumor cell `http://purl.obolibrary.org/obo/GO_0002411`

Removed

T cell tolerance induction to tumor cell definition “A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor.”
- has cross-reference “ISBN:0781735149”
- has cross-reference “PMID:16730260”
- has cross-reference “GOC:add”
T cell tolerance induction to tumor cell EquivalentTo tolerance induction to tumor cell and (process has causal agent some T cell)

Added

T cell tolerance induction to tumor cell term tracker item “https://github.com/geneontology/go-ontology/issues/20574”^^anyURI
T cell tolerance induction to tumor cell definition “A process of tolerance induction taking place in a T cell which leads to immunological tolerance of a tumor.”
- has cross-reference “ISBN:0781735149”
- has cross-reference “PMID:16730260”
- has cross-reference “GOC:add”
T cell tolerance induction to tumor cell EquivalentTo tolerance induction to tumor cell and (occurs in some T cell)

T-helper 1 cell cytokine production `http://purl.obolibrary.org/obo/GO_0035744`

Removed

T-helper 1 cell cytokine production EquivalentTo cytokine production and (process has causal agent some T-helper 1 cell)
T-helper 1 cell cytokine production SubClassOf process has causal agent some T-helper 1 cell

Added

T-helper 1 cell cytokine production EquivalentTo cytokine production and (occurs in some T-helper 1 cell)
T-helper 1 cell cytokine production SubClassOf occurs in some T-helper 1 cell

T-helper 2 cell cytokine production `http://purl.obolibrary.org/obo/GO_0035745`

Removed

T-helper 2 cell cytokine production EquivalentTo cytokine production and (process has causal agent some T-helper 2 cell)
T-helper 2 cell cytokine production SubClassOf process has causal agent some T-helper 2 cell

Added

T-helper 2 cell cytokine production EquivalentTo cytokine production and (occurs in some T-helper 2 cell)
T-helper 2 cell cytokine production SubClassOf occurs in some T-helper 2 cell

Tea1 cell-end complex `http://purl.obolibrary.org/obo/GO_0031500`

Removed

Tea1 cell-end complex definition “A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity.”
- has cross-reference “PMID:15936270”

Added

Tea1 cell-end complex definition “A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintenance of normal cell polarity.”
- has cross-reference “PMID:15936270”

Tim8-Tim13 complex `http://purl.obolibrary.org/obo/GO_7770104`

Added

Class: Tim8-Tim13 complex
Tim8-Tim13 complex term tracker item “https://github.com/geneontology/go-ontology/issues/32408”^^anyURI
Tim8-Tim13 complex created by “ai4c-agent”
Tim8-Tim13 complex creation date “2026-08-07T16:51:54Z”
Tim8-Tim13 complex has exact synonym “TIM8-13 complex”
Tim8-Tim13 complex has_obo_namespace “cellular_component”
Tim8-Tim13 complex id “GO:7770104”
Tim8-Tim13 complex definition “A chaperone complex located in the mitochondrial intermembrane space, composed of the small TIM proteins Tim8 and Tim13.”
- has cross-reference “PMID:33355130”
- has cross-reference “PMID:11101512”
Tim8-Tim13 complex label “Tim8-Tim13 complex”
Tim8-Tim13 complex SubClassOf mitochondrial intermembrane space chaperone complex
Tim8-Tim13 complex SubClassOf in taxon some Eukaryota

Tim9-Tim10 complex `http://purl.obolibrary.org/obo/GO_7770105`

Added

Class: Tim9-Tim10 complex
Tim9-Tim10 complex term tracker item “https://github.com/geneontology/go-ontology/issues/32408”^^anyURI
Tim9-Tim10 complex created by “ai4c-agent”
Tim9-Tim10 complex creation date “2026-08-07T16:51:54Z”
Tim9-Tim10 complex has exact synonym “TIM9-10 complex”
Tim9-Tim10 complex has_obo_namespace “cellular_component”
Tim9-Tim10 complex id “GO:7770105”
Tim9-Tim10 complex definition “A chaperone complex located in the mitochondrial intermembrane space, composed of the small TIM proteins Tim9 and Tim10.”
- has cross-reference “PMID:16387659”
- has cross-reference “PMID:33355130”
Tim9-Tim10 complex label “Tim9-Tim10 complex”
Tim9-Tim10 complex SubClassOf mitochondrial intermembrane space chaperone complex
Tim9-Tim10 complex SubClassOf in taxon some Eukaryota

U2 snRNA (adenine-N6)-methyltransferase activity `http://purl.obolibrary.org/obo/GO_0106348`

Added

U2 snRNA (adenine-N6)-methyltransferase activity SubClassOf RNA (adenine-N6)-methyltransferase activity

U6 snRNA (adenine(43)-N6)-methyltransferase activity `http://purl.obolibrary.org/obo/GO_0120048`

Added

U6 snRNA (adenine(43)-N6)-methyltransferase activity SubClassOf RNA (adenine-N6)-methyltransferase activity

UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminyltransferase activity `http://purl.obolibrary.org/obo/GO_0051991`

Removed

UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminyltransferase activity label “UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity”

Added

UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminyltransferase activity label “UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminyltransferase activity”

UDP-N-acetylgalactosamine biosynthetic process `http://purl.obolibrary.org/obo/GO_0019277`

Removed

UDP-N-acetylgalactosamine biosynthetic process SubClassOf obsolete UDP-N-acetylgalactosamine metabolic process

UDP-N-acetylglucosamine biosynthetic process `http://purl.obolibrary.org/obo/GO_0006048`

Removed

UDP-N-acetylglucosamine biosynthetic process SubClassOf obsolete UDP-N-acetylglucosamine metabolic process

acetyl-CoA C-myristoyltransferase activity `http://purl.obolibrary.org/obo/GO_0050633`

Removed

acetyl-CoA C-myristoyltransferase activity definition “Catalysis of the reaction: myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA.”
- has cross-reference “EC:2.3.1.155”
- has cross-reference “MetaCyc:2.3.1.155-RXN”

Added

acetyl-CoA C-myristoyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32501”^^anyURI
acetyl-CoA C-myristoyltransferase activity definition “Catalysis of the reaction: tetradecanoyl-CoA + acetyl-CoA = 3-oxohexadecanoyl-CoA + CoA.”
- has cross-reference “RHEA:18161”
acetyl-CoA C-myristoyltransferase activity SubClassOf acetyl-CoA C-acyltransferase activity

actin filament-based process `http://purl.obolibrary.org/obo/GO_0030029`

Removed

actin filament-based process EquivalentTo cellular process and (process has causal agent some actin filament)

alcohol dehydrogenase (NAD+) activity `http://purl.obolibrary.org/obo/GO_0004022`

Removed

alcohol dehydrogenase (NAD+) activity has cross-reference “RHEA:12785”
alcohol dehydrogenase (NAD+) activity narrowMatch 12785

aldose reductase [NAD(P)H] activity `http://purl.obolibrary.org/obo/GO_0004032`

Removed

aldose reductase [NAD(P)H] activity has exact synonym “alditol:NADP+ 1-oxidoreductase activity”
aldose reductase [NAD(P)H] activity broadMatch ALDEHYDE-REDUCTASE-RXN
aldose reductase [NAD(P)H] activity broadMatch 1.1.1.21
aldose reductase [NAD(P)H] activity exactMatch 12789
aldose reductase [NAD(P)H] activity exactMatch R02820
aldose reductase [NAD(P)H] activity definition “Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.”
- has cross-reference “EC:1.1.1.21”
aldose reductase [NAD(P)H] activity has_related_synonym “aldose reductase activity”
- has cross-reference “EC:1.1.1.21”
aldose reductase [NAD(P)H] activity label “aldose reductase (NADPH) activity”
aldose reductase [NAD(P)H] activity SubClassOf alcohol dehydrogenase (NADP+) activity
aldose reductase [NAD(P)H] activity SubClassOf has participant some hydron
aldose reductase [NAD(P)H] activity SubClassOf has participant some aldose
aldose reductase [NAD(P)H] activity SubClassOf has participant some alditol
aldose reductase [NAD(P)H] activity SubClassOf has participant some NADPH(4-)
aldose reductase [NAD(P)H] activity SubClassOf has participant some NADP(3-)

Added

aldose reductase [NAD(P)H] activity has cross-reference “EC:1.1.1.21”
aldose reductase [NAD(P)H] activity has cross-reference “MetaCyc:ALDEHYDE-REDUCTASE-RXN”
aldose reductase [NAD(P)H] activity has cross-reference “RHEA:12785”
aldose reductase [NAD(P)H] activity has narrow synonym “alditol:NADP+ 1-oxidoreductase activity”
aldose reductase [NAD(P)H] activity has narrow synonym “aldose reductase (NADPH) activity”
aldose reductase [NAD(P)H] activity exactMatch ALDEHYDE-REDUCTASE-RXN
aldose reductase [NAD(P)H] activity exactMatch 1.1.1.21
aldose reductase [NAD(P)H] activity narrowMatch 12785
aldose reductase [NAD(P)H] activity narrowMatch 12789
aldose reductase [NAD(P)H] activity narrowMatch R02820
aldose reductase [NAD(P)H] activity definition “Catalysis of the reaction: an alditol + NAD(P)+ = an aldose + NAD(P)H + H+.”
- has cross-reference “EC:1.1.1.21”
aldose reductase [NAD(P)H] activity has exact synonym “alditol:NAD(P)+ 1-oxidoreductase activity”
- has cross-reference “EC:1.1.1.21”
aldose reductase [NAD(P)H] activity has exact synonym “aldose reductase activity”
- has cross-reference “EC:1.1.1.21”
aldose reductase [NAD(P)H] activity label “aldose reductase [NAD(P)H] activity”
aldose reductase [NAD(P)H] activity SubClassOf alcohol dehydrogenase [NAD(P)+] activity

amino acid–[peptidyl-carrier protein] ligase activity `http://purl.obolibrary.org/obo/GO_7770118`

Added

Class: amino acid–[peptidyl-carrier protein] ligase activity
amino acid–[peptidyl-carrier protein] ligase activity term tracker item “https://github.com/geneontology/go-ontology/issues/30872”^^anyURI
amino acid–[peptidyl-carrier protein] ligase activity created by “ai4c-agent”
amino acid–[peptidyl-carrier protein] ligase activity creation date “2026-09-03T23:34:51Z”
amino acid–[peptidyl-carrier protein] ligase activity has cross-reference “RHEA:11656”
amino acid–[peptidyl-carrier protein] ligase activity has cross-reference “RHEA:59436”
amino acid–[peptidyl-carrier protein] ligase activity has cross-reference “RHEA:61680”
amino acid–[peptidyl-carrier protein] ligase activity has cross-reference “RHEA:61688”
amino acid–[peptidyl-carrier protein] ligase activity has cross-reference “RHEA:61696”
amino acid–[peptidyl-carrier protein] ligase activity has cross-reference “RHEA:61704”
amino acid–[peptidyl-carrier protein] ligase activity has cross-reference “RHEA:61788”
amino acid–[peptidyl-carrier protein] ligase activity has cross-reference “RHEA:61800”
amino acid–[peptidyl-carrier protein] ligase activity has cross-reference “RHEA:62452”
amino acid–[peptidyl-carrier protein] ligase activity has cross-reference “RHEA:62492”
amino acid–[peptidyl-carrier protein] ligase activity has_obo_namespace “molecular_function”
amino acid–[peptidyl-carrier protein] ligase activity has_related_synonym “NRPS adenylation domain activity”
amino acid–[peptidyl-carrier protein] ligase activity has_related_synonym “amino acid adenylylation by nonribosomal peptide synthase”
amino acid–[peptidyl-carrier protein] ligase activity id “GO:7770118”
amino acid–[peptidyl-carrier protein] ligase activity narrowMatch 11656
amino acid–[peptidyl-carrier protein] ligase activity narrowMatch 59436
amino acid–[peptidyl-carrier protein] ligase activity narrowMatch 61680
amino acid–[peptidyl-carrier protein] ligase activity narrowMatch 61688
amino acid–[peptidyl-carrier protein] ligase activity narrowMatch 61696
amino acid–[peptidyl-carrier protein] ligase activity narrowMatch 61704
amino acid–[peptidyl-carrier protein] ligase activity narrowMatch 61788
amino acid–[peptidyl-carrier protein] ligase activity narrowMatch 61800
amino acid–[peptidyl-carrier protein] ligase activity narrowMatch 62452
amino acid–[peptidyl-carrier protein] ligase activity narrowMatch 62492
amino acid–[peptidyl-carrier protein] ligase activity definition “Catalysis of the ATP-dependent activation of an amino acid and its transfer as a thiol ester to the phosphopantetheine prosthetic group of a peptidyl-carrier protein, according to the reaction: an amino acid + ATP + holo-[peptidyl-carrier protein] = an aminoacyl-[peptidyl-carrier protein] + AMP + diphosphate. This is the reaction carried out by adenylation (A) domains of nonribosomal peptide synthetases, and by the standalone type II adenylation enzymes that load amino acids onto peptidyl-carrier proteins in related assembly lines.”
- has cross-reference “PMID:17502372”
- has cross-reference “PMID:9250661”
amino acid–[peptidyl-carrier protein] ligase activity label “amino acid–[peptidyl-carrier protein] ligase activity”
amino acid–[peptidyl-carrier protein] ligase activity SubClassOf acid-thiol ligase activity

aminophospholipid flippase activity `http://purl.obolibrary.org/obo/GO_0015247`

Added

aminophospholipid flippase activity conformsTo lipid_flippase_activity.yaml

ammonia assimilation cycle `http://purl.obolibrary.org/obo/GO_0019676`

Added

ammonia assimilation cycle term tracker item “https://github.com/geneontology/go-ontology/issues/32376”^^anyURI
ammonia assimilation cycle SubClassOf nutrient assimilation

anatomical entity `http://purl.obolibrary.org/obo/UBERON_0001062`

Added

anatomical entity definition “Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.”

antennal development `http://purl.obolibrary.org/obo/GO_0007469`

Removed

antennal development definition “The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.”
- has cross-reference “http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004526”

Added

antennal development term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
antennal development definition “The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.”
- has cross-reference “FBbt:00004511”

anterior compartment pattern formation `http://purl.obolibrary.org/obo/GO_0007387`

Removed

anterior compartment pattern formation definition “The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

anterior compartment pattern formation term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
anterior compartment pattern formation definition “The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo.”
- has cross-reference “ISBN:0879694238”

anterior region determination `http://purl.obolibrary.org/obo/GO_0007355`

Removed

anterior region determination definition “Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

anterior region determination term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
anterior region determination definition “Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product.”
- has cross-reference “ISBN:0879694238”

anterior/posterior axis specification, embryo `http://purl.obolibrary.org/obo/GO_0008595`

Removed

anterior/posterior axis specification, embryo definition “The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

anterior/posterior axis specification, embryo definition “The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.”
- has cross-reference “ISBN:0879694238”

antigen processing and presentation following phagocytosis `http://purl.obolibrary.org/obo/GO_0002747`

Added

antigen processing and presentation following phagocytosis term tracker item “https://github.com/geneontology/go-ontology/issues/32152”^^anyURI
antigen processing and presentation following phagocytosis SubClassOf preceded by some phagocytosis

assembly of large subunit precursor of preribosome `http://purl.obolibrary.org/obo/GO_1902626`

Removed

assembly of large subunit precursor of preribosome SubClassOf part of some ribosomal large subunit assembly

Added

assembly of large subunit precursor of preribosome term tracker item “https://github.com/geneontology/go-ontology/issues/32473”^^anyURI
assembly of large subunit precursor of preribosome SubClassOf part of some cytosolic large ribosomal subunit assembly

autophagy cargo adaptor activity `http://purl.obolibrary.org/obo/GO_0160247`

Removed

autophagy cargo adaptor activity SubClassOf part of some obsolete substrate localization to autophagosome

Added

autophagy cargo adaptor activity SubClassOf part of some macroautophagy

axonemal microtubule doublet inner sheath `http://purl.obolibrary.org/obo/GO_0160110`

Removed

axonemal microtubule doublet inner sheath definition “A structural network of microtubule inner proteins (MIPs) located inside the lumens of the A and B tubules of the axonemal microtuble doublet that helps stabilize the doublet microtubule.”
- has cross-reference “PMID:37295417”
- has cross-reference “GOC:krc”
- has cross-reference “PMID:29430673”

Added

axonemal microtubule doublet inner sheath definition “A structural network of microtubule inner proteins (MIPs) located inside the lumens of the A and B tubules of the axonemal microtubule doublet that helps stabilize the doublet microtubule.”
- has cross-reference “PMID:37295417”
- has cross-reference “GOC:krc”
- has cross-reference “PMID:29430673”

axonemal microtubule doublet ribbon `http://purl.obolibrary.org/obo/GO_0160115`

Removed

axonemal microtubule doublet ribbon definition “The 3 protofilaments A11, A12, and A13 of the A tubule along with associated inner sheath microtuble inner proteins (MIPs), either in the lumen of the A tubule or of the B tubule, which stabilize these three filiments within the axonemal doublet microtubule. The ribbon protofilaments separate the lumens of the A and B tubules.”
- has cross-reference “GOC:krc”
- has cross-reference “PMID:29430673”
- has cross-reference “PMID:1262413”

Added

axonemal microtubule doublet ribbon definition “The 3 protofilaments A11, A12, and A13 of the A tubule along with associated inner sheath microtubule inner proteins (MIPs), either in the lumen of the A tubule or of the B tubule, which stabilize these three filaments within the axonemal doublet microtubule. The ribbon protofilaments separate the lumens of the A and B tubules.”
- has cross-reference “GOC:krc”
- has cross-reference “PMID:29430673”
- has cross-reference “PMID:1262413”

bI3 intron splicing complex `http://purl.obolibrary.org/obo/GO_0106392`

Removed

bI3 intron splicing complex definition “Aprotein complex required for the splicing of intron 3 of the cytochrome b (COB) gene. In S. cerevisiae, the complex contains the maturase bI3 (which derives from one of the products of the splicing), the MRS1 cofactor and the intron 4 of the cytochrome b pre-mRNA. The two proteins stimulate the ribozyme activity of the pre-mRNA which autoctalyse a group I intron splicing.”
- has cross-reference “PMID:11773622”
- has cross-reference “GOC:lnp”

Added

bI3 intron splicing complex definition “A protein complex required for the splicing of intron 3 of the cytochrome b (COB) gene. In S. cerevisiae, the complex contains the maturase bI3 (which derives from one of the products of the splicing), the MRS1 cofactor and the intron 4 of the cytochrome b pre-mRNA. The two proteins stimulate the ribozyme activity of the pre-mRNA which autocatalyze a group I intron splicing.”
- has cross-reference “PMID:11773622”
- has cross-reference “GOC:lnp”

bI4 intron splicing complex `http://purl.obolibrary.org/obo/GO_0106391`

Removed

bI4 intron splicing complex definition “A protein complex required for the splicing of intron 4 of the cytochrome b (COB) gene. In S. cerevisiae, the complex contains the maturase bI4 (which derives from one of the products of the splicing), Leucyl-tRNA synthetase NAM2 and the intron 4 of the cytochrome b pre-mRNA. The two proteins stimulate the ribozyme activity of the pre-mRNA which autoctalyse a group I intron splicing.”
- has cross-reference “GOC:lnp”
- has cross-reference “PMID:19622748”

Added

bI4 intron splicing complex definition “A protein complex required for the splicing of intron 4 of the cytochrome b (COB) gene. In S. cerevisiae, the complex contains the maturase bI4 (which derives from one of the products of the splicing), Leucyl-tRNA synthetase NAM2 and the intron 4 of the cytochrome b pre-mRNA. The two proteins stimulate the ribozyme activity of the pre-mRNA which autocatalyze a group I intron splicing.”
- has cross-reference “GOC:lnp”
- has cross-reference “PMID:19622748”

basophil mediated immunity `http://purl.obolibrary.org/obo/GO_0002560`

Removed

basophil mediated immunity EquivalentTo immune system process and (process has causal agent some basophil)

binding `http://purl.obolibrary.org/obo/GO_0005488`

Added

binding term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI
binding in_subset gocheck_do_not_annotate

bioadhesive activity `http://purl.obolibrary.org/obo/GO_0140073`

Removed

bioadhesive activity definition “A structural molecule ativity that mediates an organism’s attachment to an environmental substrate via stable, non-selective binding by a protein to an external surface. Examples includes proteins used by insects to anchor pupae to surfaces.”
- has cross-reference “PMID:39370426”

Added

bioadhesive activity definition “A structural molecule activity that mediates an organism’s attachment to an environmental substrate via stable, non-selective binding by a protein to an external surface. Examples includes proteins used by insects to anchor pupae to surfaces.”
- has cross-reference “PMID:39370426”

biological_process `http://purl.obolibrary.org/obo/GO_0008150`

Added

biological_process definition “A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.”

bipolar cell growth `http://purl.obolibrary.org/obo/GO_0042815`

Removed

bipolar cell growth comment “Bipolar cell growth refers to a change in both cell size and cell shape. For shape changes where cell size is not affected, consider instead the term ‘establishment or maintenance of bipolar cell polarity resulting in cell shape ; GO:0061246’ and its children.”

Added

bipolar cell growth comment “Bipolar cell growth refers to a change in both cell size and cell shape. For shape changes where cell size is not affected, consider instead the term ‘establishment or maintenance of bipolar cell polarity; GO:0061245’ and its children.”

blastoderm segmentation `http://purl.obolibrary.org/obo/GO_0007350`

Removed

blastoderm segmentation definition “The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

blastoderm segmentation term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
blastoderm segmentation definition “The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.”
- has cross-reference “ISBN:0879694238”

carboxylic acid biosynthetic process `http://purl.obolibrary.org/obo/GO_0046394`

Added

carboxylic acid biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI
carboxylic acid biosynthetic process in_subset gocheck_do_not_annotate

carboxylic acid catabolic process `http://purl.obolibrary.org/obo/GO_0046395`

Added

carboxylic acid catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI
carboxylic acid catabolic process in_subset gocheck_do_not_annotate

cell `http://purl.obolibrary.org/obo/CL_0000000`

Added

cell definition “A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.”

cell-cell junction disassembly `http://purl.obolibrary.org/obo/GO_0150147`

Added

cell-cell junction disassembly never in taxon Fungi
cell-cell junction disassembly SubClassOf not (in taxon some Fungi)

cell-cell junction maintenance `http://purl.obolibrary.org/obo/GO_0045217`

Added

cell-cell junction maintenance never in taxon Fungi
cell-cell junction maintenance SubClassOf not (in taxon some Fungi)

cell-cell junction organization `http://purl.obolibrary.org/obo/GO_0045216`

Added

cell-cell junction organization never in taxon Fungi
cell-cell junction organization SubClassOf not (in taxon some Fungi)

cellular response to interleukin-5 `http://purl.obolibrary.org/obo/GO_7770103`

Added

Class: cellular response to interleukin-5
cellular response to interleukin-5 term tracker item “https://github.com/geneontology/go-ontology/issues/32411”^^anyURI
cellular response to interleukin-5 created by “ai4c-agent”
cellular response to interleukin-5 creation date “2026-08-04T23:16:15Z”
cellular response to interleukin-5 has exact synonym “cellular response to IL-5”
cellular response to interleukin-5 has_obo_namespace “biological_process”
cellular response to interleukin-5 id “GO:7770103”
cellular response to interleukin-5 definition “Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-5 stimulus.”
- has cross-reference “PMID:41207640”
cellular response to interleukin-5 label “cellular response to interleukin-5”
cellular response to interleukin-5 SubClassOf cellular response to cytokine stimulus
cellular response to interleukin-5 SubClassOf response to interleukin-5

cellular_component `http://purl.obolibrary.org/obo/GO_0005575`

Added

cellular_component definition “A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).”

ceramide floppase activity `http://purl.obolibrary.org/obo/GO_0099038`

Added

ceramide floppase activity conformsTo lipid_floppase_activity.yaml

ceramide transfer activity `http://purl.obolibrary.org/obo/GO_0120017`

Added

ceramide transfer activity conformsTo intermembrane_lipid_transfer_activity.yaml

cerebroside transfer activity `http://purl.obolibrary.org/obo/GO_0140340`

Added

cerebroside transfer activity conformsTo intermembrane_lipid_transfer_activity.yaml

chitin-based cuticle development `http://purl.obolibrary.org/obo/GO_0040003`

Removed

chitin-based cuticle development conformsTo anatomical_structure_development.yaml

chloroplast outer membrane translocon `http://purl.obolibrary.org/obo/GO_0010278`

Removed

chloroplast outer membrane translocon definition “The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner.”
- has cross-reference “PMID:11299338”

Added

chloroplast outer membrane translocon definition “The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP-dependent manner.”
- has cross-reference “PMID:11299338”

chloroplast protein-transporting ATPase activity `http://purl.obolibrary.org/obo/GO_0016464`

Removed

chloroplast protein-transporting ATPase activity definition “Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma.”
- has cross-reference “EC:7.4.2.4”

Added

chloroplast protein-transporting ATPase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32395”^^anyURI
chloroplast protein-transporting ATPase activity definition “Enables the transfer of a protein from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma.”
- has cross-reference “EC:7.4.2.4”

chorion-containing eggshell formation `http://purl.obolibrary.org/obo/GO_0007304`

Removed

chorion-containing eggshell formation conformsTo anatomical_structure_formation.yaml

chromosome movement towards spindle pole `http://purl.obolibrary.org/obo/GO_0051305`

Removed

chromosome movement towards spindle pole EquivalentTo localization and (has target end location some spindle pole) and (process has causal agent some microtubule) and (has primary input some chromosome)

Added

chromosome movement towards spindle pole EquivalentTo localization and (has target end location some spindle pole) and (has primary input some chromosome)

cilium movement `http://purl.obolibrary.org/obo/GO_0003341`

Removed

cilium movement EquivalentTo microtubule-based movement and (results in movement of some cilium) and (process has causal agent some microtubule)

Added

cilium movement EquivalentTo microtubule-based movement and (results in movement of some cilium)

citrate-malate shuttle `http://purl.obolibrary.org/obo/GO_7770108`

Added

Class: citrate-malate shuttle
citrate-malate shuttle term tracker item “https://github.com/geneontology/go-ontology/issues/32353”^^anyURI
citrate-malate shuttle created by “ai4c-agent”
citrate-malate shuttle creation date “2026-08-12T10:08:31Z”
citrate-malate shuttle has cross-reference “Wikipedia:Citrate-malate_shuttle”
citrate-malate shuttle has exact synonym “citrate-malate cycle”
citrate-malate shuttle has exact synonym “malate-citrate shuttle”
citrate-malate shuttle has narrow synonym “acetyl-CoA biosynthesis from citrate”
citrate-malate shuttle has_obo_namespace “biological_process”
citrate-malate shuttle has_related_synonym “non-canonical TCA cycle”
citrate-malate shuttle id “GO:7770108”
citrate-malate shuttle definition “The process of transferring acetyl-CoA from the mitochondrion to the cytosol via citrate. Acetyl-CoA and oxaloacetate produced in the mitochondrion are condensed to citrate by citrate synthase; the citrate is exported to the cytosol by the mitochondrial citrate/malate antiporter in exchange for malate; in the cytosol, ATP citrate lyase cleaves the citrate back to acetyl-CoA and oxaloacetate; the oxaloacetate is then reduced to malate by cytosolic malate dehydrogenase, and the malate is imported back into the mitochondrion to complete the cycle.”
- has cross-reference “PMID:35264789”
- has cross-reference “PMID:32414018”
citrate-malate shuttle label “citrate-malate shuttle”
citrate-malate shuttle EquivalentTo metabolic process and (has part some ATP citrate synthase activity) and (has part some L-malate dehydrogenase (NAD+) activity)
citrate-malate shuttle SubClassOf acetyl-CoA metabolic process
citrate-malate shuttle SubClassOf citrate metabolic process
citrate-malate shuttle SubClassOf has part some ATP citrate synthase activity
citrate-malate shuttle SubClassOf has part some mitochondrial citrate transmembrane transport
citrate-malate shuttle SubClassOf has part some L-malate dehydrogenase (NAD+) activity
citrate-malate shuttle SubClassOf has primary output some acetyl-CoA(4-)
citrate-malate shuttle SubClassOf has primary input some citrate(3-)

citrate:2-oxoglutarate antiporter activity `http://purl.obolibrary.org/obo/GO_0180056`

Removed

citrate:2-oxoglutarate antiporter activity definition “Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + 2-oxogluarate(in) = citrate(in) + 2-oxogluarat(out).”
- has cross-reference “PMID:20371607”

Added

citrate:2-oxoglutarate antiporter activity definition “Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + 2-oxoglutarate(in) = citrate(in) + 2-oxoglutarate(out).”
- has cross-reference “PMID:20371607”

clathrin coat assembly involved in endocytosis `http://purl.obolibrary.org/obo/GO_0099049`

Removed

clathrin coat assembly involved in endocytosis definition “The process that results in the assembly of clathrin triskelia into a clathrin cage during endocytosis. Clathrin is recruited to the plasma membrane via interaction with scaffolding proteins that bridge between clathtin and cell surface receptors. Clathrin coat formation is concomittant with coated pit formation leading to endocytic vesicle formation.”
- has cross-reference “PMID:21779028”

Added

clathrin coat assembly involved in endocytosis definition “The process that results in the assembly of clathrin triskelia into a clathrin cage during endocytosis. Clathrin is recruited to the plasma membrane via interaction with scaffolding proteins that bridge between clathrin and cell surface receptors. Clathrin coat formation is concomitant with coated pit formation leading to endocytic vesicle formation.”
- has cross-reference “PMID:21779028”

cochlear hair cell ribbon synapse `http://purl.obolibrary.org/obo/GO_0098683`

Removed

cochlear hair cell ribbon synapse definition “A ribbon synpase of an auditory hair cell of the cochlear. These ribbon synapses contain spherical synaptic ribbons and lack and arciform density.”
- has cross-reference “PMID:15626493”

Added

cochlear hair cell ribbon synapse definition “A ribbon synapse of an auditory hair cell of the cochlear. These ribbon synapses contain spherical synaptic ribbons and lack arciform density.”
- has cross-reference “PMID:15626493”

coenzyme A phosphatase activity `http://purl.obolibrary.org/obo/GO_0140477`

Added

Class: coenzyme A phosphatase activity
coenzyme A phosphatase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32572”^^anyURI
coenzyme A phosphatase activity created by “pg”
coenzyme A phosphatase activity creation date “2026-09-08T11:43:30Z”
coenzyme A phosphatase activity has_obo_namespace “molecular_function”
coenzyme A phosphatase activity id “GO:0140477”
coenzyme A phosphatase activity definition “Catalysis of the reaction: CoA + H2O = 3’-dephospho-CoA + phosphate.”
- has cross-reference “PMID:42033660”
coenzyme A phosphatase activity label “coenzyme A phosphatase activity”
coenzyme A phosphatase activity SubClassOf phosphatase activity

collagen and cuticulin-based cuticle development `http://purl.obolibrary.org/obo/GO_0040002`

Removed

collagen and cuticulin-based cuticle development conformsTo anatomical_structure_development.yaml

compartment pattern specification `http://purl.obolibrary.org/obo/GO_0007386`

Removed

compartment pattern specification definition “The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

compartment pattern specification term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
compartment pattern specification definition “The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation.”
- has cross-reference “ISBN:0879694238”

copper chaperone activity `http://purl.obolibrary.org/obo/GO_0016531`

Added

copper chaperone activity conformsTo molecular_carrier_activity.yaml

corticotropin-releasing factor receptor activity `http://purl.obolibrary.org/obo/GO_0015056`

Removed

corticotropin-releasing factor receptor activity definition “Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity.”
- has cross-reference “PMID:12032352”
corticotropin-releasing factor receptor activity label “corticotrophin-releasing factor receptor activity”

Added

corticotropin-releasing factor receptor activity definition “Combining with the corticotropin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity.”
- has cross-reference “PMID:12032352”
corticotropin-releasing factor receptor activity label “corticotropin-releasing factor receptor activity”

corticotropin-releasing hormone receptor activity `http://purl.obolibrary.org/obo/GO_0043404`

Removed

corticotropin-releasing hormone receptor activity has exact synonym “corticotropin-releasing factor receptor activity”
- has cross-reference “GOC:bf”

Added

corticotropin-releasing hormone receptor activity has exact synonym “corticotropin releasing factor receptor activity”
- has cross-reference “GOC:bf”

creatine biosynthetic process `http://purl.obolibrary.org/obo/GO_0006601`

Added

creatine biosynthetic process never in taxon Archaea
creatine biosynthetic process never in taxon Viridiplantae
creatine biosynthetic process never in taxon Schizosaccharomyces pombe
creatine biosynthetic process never in taxon Insecta
creatine biosynthetic process SubClassOf not (in taxon some Archaea)
creatine biosynthetic process SubClassOf not (in taxon some Viridiplantae)
creatine biosynthetic process SubClassOf not (in taxon some Schizosaccharomyces pombe)
creatine biosynthetic process SubClassOf not (in taxon some Insecta)

creatine metabolic process `http://purl.obolibrary.org/obo/GO_0006600`

Added

creatine metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32279”^^anyURI
creatine metabolic process never in taxon Archaea
creatine metabolic process never in taxon Viridiplantae
creatine metabolic process never in taxon Schizosaccharomyces pombe
creatine metabolic process never in taxon Insecta
creatine metabolic process SubClassOf not (in taxon some Archaea)
creatine metabolic process SubClassOf not (in taxon some Viridiplantae)
creatine metabolic process SubClassOf not (in taxon some Schizosaccharomyces pombe)
creatine metabolic process SubClassOf not (in taxon some Insecta)

cuticle development `http://purl.obolibrary.org/obo/GO_0042335`

Removed

cuticle development conformsTo anatomical_structure_development.yaml

cyclic ADP-ribose hydrolase activity `http://purl.obolibrary.org/obo/GO_0061812`

Removed

cyclic ADP-ribose hydrolase activity term replaced by NAD+ nucleosidase activity, cyclic ADP-ribose generating
cyclic ADP-ribose hydrolase activity definition “OBSOLETE. Catalysis of the reaction: cyclic ADP-ribose + H20 = ADP-ribose (ADPR).”
- has cross-reference “GOC:dph”
- has cross-reference “GOC:PARL”
- has cross-reference “GOC:pad”
- has cross-reference “PMID:11866528”
cyclic ADP-ribose hydrolase activity deprecated true
cyclic ADP-ribose hydrolase activity comment “This term was obsoleted because it represents a step in a multi-step reaction.”
cyclic ADP-ribose hydrolase activity label “obsolete cyclic ADP-ribose hydrolase”

Added

cyclic ADP-ribose hydrolase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32457”^^anyURI
cyclic ADP-ribose hydrolase activity has cross-reference “RHEA:38615”
cyclic ADP-ribose hydrolase activity has exact synonym “cADPR hydrolase activity”
cyclic ADP-ribose hydrolase activity exactMatch 38615
cyclic ADP-ribose hydrolase activity definition “Catalysis of the reaction: cyclic ADP-beta-D-ribose + H2O = ADP-D-ribose.”
- has cross-reference “PMID:42243876”
- has cross-reference “RHEA:38615”
cyclic ADP-ribose hydrolase activity comment “Note that this term was reinstated from obsolete.”
cyclic ADP-ribose hydrolase activity label “cyclic ADP-ribose hydrolase activity”
cyclic ADP-ribose hydrolase activity SubClassOf hydrolase activity, hydrolyzing N-glycosyl compounds
cyclic ADP-ribose hydrolase activity SubClassOf has participant some water
cyclic ADP-ribose hydrolase activity SubClassOf has participant some ADP-D-ribose(2-)
cyclic ADP-ribose hydrolase activity SubClassOf has participant some cyclic ADP-beta-D-ribose(2-)

cytoplasm protein quality control `http://purl.obolibrary.org/obo/GO_0140455`

Removed

cytoplasm protein quality control definition “The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.”
- has cross-reference “PMID:32075773”

Added

cytoplasm protein quality control term tracker item “https://github.com/geneontology/go-ontology/issues/32274”^^anyURI
cytoplasm protein quality control term tracker item “https://github.com/geneontology/go-ontology/issues/32442”^^anyURI
cytoplasm protein quality control definition “The chemical reactions and pathways resulting in the breakdown or refolding of aberrant proteins in the cytoplasm, including misfolded proteins and orphan subunits that fail to assemble into their cognate protein complex, in which the substrates are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.”
- has cross-reference “PMID:32075773”
- has cross-reference “PMID:35316660”
- has cross-reference “PMID:30075143”

cytosol to ERGIC protein transport `http://purl.obolibrary.org/obo/GO_0106273`

Removed

cytosol to ERGIC protein transport definition “The directed movement of proteins from the cystosol to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC).”
- has cross-reference “PMID:32272059”

Added

cytosol to ERGIC protein transport definition “The directed movement of proteins from the cytosol to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC).”
- has cross-reference “PMID:32272059”

dendritic cell cytokine production `http://purl.obolibrary.org/obo/GO_0002371`

Removed

dendritic cell cytokine production comment “Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the ‘regulation’ children terms.”
dendritic cell cytokine production EquivalentTo cytokine production and (process has causal agent some dendritic cell)
dendritic cell cytokine production SubClassOf process has causal agent some dendritic cell

Added

dendritic cell cytokine production term tracker item “https://github.com/geneontology/go-ontology/issues/20574”^^anyURI
dendritic cell cytokine production comment “Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the ‘regulation’ children terms. The is_a link to GO:0002443 is asserted rather than inferred because GO:0002443 has no logical definition; it must be maintained by hand (see #20574).”
dendritic cell cytokine production EquivalentTo cytokine production and (occurs in some dendritic cell)
dendritic cell cytokine production SubClassOf occurs in some dendritic cell

dermatan sulfate proteoglycan biosynthetic process `http://purl.obolibrary.org/obo/GO_0050651`

Removed

dermatan sulfate proteoglycan biosynthetic process definition “The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycans, which consist of a core protein linked to a dermatan sulfate glycosaminoglycan. The dermatan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-D-hexuronic acid-beta-(1,3)-N-acetyl-D-galactosamine. Tthe former can be a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter can be O-sulfated. Dermatan sulfate chains are covalently linked to serine/threonine residues (O-linked) of the core protein via a tetrasaccharide linker sequence (xylose-galactose-galactose-glucuronate).”
- has cross-reference “PMID:17239763”

Added

dermatan sulfate proteoglycan biosynthetic process definition “The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycans, which consist of a core protein linked to a dermatan sulfate glycosaminoglycan. The dermatan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-D-hexuronic acid-beta-(1,3)-N-acetyl-D-galactosamine. The former can be a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter can be O-sulfated. Dermatan sulfate chains are covalently linked to serine/threonine residues (O-linked) of the core protein via a tetrasaccharide linker sequence (xylose-galactose-galactose-glucuronate).”
- has cross-reference “PMID:17239763”

desmosome disassembly `http://purl.obolibrary.org/obo/GO_0035921`

Added

desmosome disassembly never in taxon Fungi
desmosome disassembly SubClassOf not (in taxon some Fungi)

desmosome maintenance `http://purl.obolibrary.org/obo/GO_0002160`

Added

desmosome maintenance never in taxon Fungi
desmosome maintenance SubClassOf not (in taxon some Fungi)

desmosome organization `http://purl.obolibrary.org/obo/GO_0002934`

Added

desmosome organization never in taxon Fungi
desmosome organization SubClassOf not (in taxon some Fungi)

determination of genital disc primordium `http://purl.obolibrary.org/obo/GO_0035225`

Removed

determination of genital disc primordium definition “Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two.”
- has cross-reference “PMID:11494318”
- has cross-reference “GOC:bf”

Added

determination of genital disc primordium definition “Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primordium located anteriorly, the anal primordium located posteriorly, and the male genital primordium between the two.”
- has cross-reference “PMID:11494318”
- has cross-reference “GOC:bf”

diacylglyceride transfer activity `http://purl.obolibrary.org/obo/GO_0140337`

Added

diacylglyceride transfer activity conformsTo intermembrane_lipid_transfer_activity.yaml

dihydrolipoyl dehydrogenase (NADH) activity `http://purl.obolibrary.org/obo/GO_0004148`

Added

dihydrolipoyl dehydrogenase (NADH) activity term tracker item “https://github.com/geneontology/go-ontology/issues/32557”^^anyURI
dihydrolipoyl dehydrogenase (NADH) activity broadMatch 30795

dihydrolipoyllysine-residue glutaryltransferase activity `http://purl.obolibrary.org/obo/GO_0120571`

Added

dihydrolipoyllysine-residue glutaryltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32557”^^anyURI
dihydrolipoyllysine-residue glutaryltransferase activity broadMatch 30795
dihydrolipoyllysine-residue glutaryltransferase activity exactMatch 86675

dinoflagellate peduncle `http://purl.obolibrary.org/obo/GO_1990905`

Removed

dinoflagellate peduncle definition “A small, flexible, finger-like projection of cytoplasm containing an array of microtubles and located near the flagellar pores in some photosynthetic as well as nonphotosynthetic dinoflagellate species. Its functions are not fully understood, but it has been associated with feeding behavior (phagotrophy).”
- has cross-reference “GOC:at”
- has cross-reference “Wikipedia:Dinoflagellate”
- has cross-reference “PMID:1480107”

Added

dinoflagellate peduncle definition “A small, flexible, finger-like projection of cytoplasm containing an array of microtubules and located near the flagellar pores in some photosynthetic as well as nonphotosynthetic dinoflagellate species. Its functions are not fully understood, but it has been associated with feeding behavior (phagotrophy).”
- has cross-reference “GOC:at”
- has cross-reference “Wikipedia:Dinoflagellate”
- has cross-reference “PMID:1480107”

dissimilatory sulfate reduction `http://purl.obolibrary.org/obo/GO_0019420`

Removed

dissimilatory sulfate reduction SubClassOf sulfate assimilation

Added

dissimilatory sulfate reduction SubClassOf sulfur compound metabolic process

eggshell formation `http://purl.obolibrary.org/obo/GO_0030703`

Removed

eggshell formation conformsTo anatomical_structure_formation.yaml

endoplasmic reticulum protein quality control `http://purl.obolibrary.org/obo/GO_0170080`

Added

Class: endoplasmic reticulum protein quality control
endoplasmic reticulum protein quality control term tracker item “https://github.com/geneontology/go-ontology/issues/32495”^^anyURI
endoplasmic reticulum protein quality control created by “ew”
endoplasmic reticulum protein quality control creation date “2026-08-20T16:01:05Z”
endoplasmic reticulum protein quality control has_obo_namespace “biological_process”
endoplasmic reticulum protein quality control has_related_synonym “ERQC”
endoplasmic reticulum protein quality control id “GO:0170080”
endoplasmic reticulum protein quality control definition “Any process that monitors and mediates the fidelity of protein folding in the endoplasmic reticulum, or prevents misfolded proteins from accumulating in or transiting the endoplasmic reticulum. Processes result in the export of correctly folded proteins to the Golgi apparatus while retaining, refolding, or targeting terminally misfolded proteins for degradation.”
- has cross-reference “PMID:12612637”
- has cross-reference “PMID:17129784”
endoplasmic reticulum protein quality control label “endoplasmic reticulum protein quality control”
endoplasmic reticulum protein quality control SubClassOf protein quality control

endoplasmic reticulum stress-induced pre-emptive quality control `http://purl.obolibrary.org/obo/GO_0061857`

Removed

endoplasmic reticulum stress-induced pre-emptive quality control has exact synonym “ER stress-indiced pre-emptive quality control”
endoplasmic reticulum stress-induced pre-emptive quality control definition “The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome.”
- has cross-reference “PMID:26565908”
- has cross-reference “PMID:17129784”

Added

endoplasmic reticulum stress-induced pre-emptive quality control term tracker item “https://github.com/geneontology/go-ontology/issues/20914”^^anyURI
endoplasmic reticulum stress-induced pre-emptive quality control has exact synonym “ER stress-induced pre-emptive quality control”
endoplasmic reticulum stress-induced pre-emptive quality control definition “The response to endoplasmic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome.”
- has cross-reference “PMID:26565908”
- has cross-reference “PMID:17129784”
endoplasmic reticulum stress-induced pre-emptive quality control SubClassOf endoplasmic reticulum protein quality control

endoplasmic reticulum unfolded protein response `http://purl.obolibrary.org/obo/GO_0030968`

Added

endoplasmic reticulum unfolded protein response term tracker item “https://github.com/geneontology/go-ontology/issues/20914”^^anyURI
endoplasmic reticulum unfolded protein response SubClassOf part of some endoplasmic reticulum protein quality control

ent-kaurene biosynthetic process `http://purl.obolibrary.org/obo/GO_0033332`

Removed

ent-kaurene biosynthetic process SubClassOf obsolete ent-kaurene metabolic process

eosinophil mediated immunity `http://purl.obolibrary.org/obo/GO_0002447`

Removed

eosinophil mediated immunity EquivalentTo immune system process and (process has causal agent some eosinophil)

exit from cytosolic ribosome hibernation `http://purl.obolibrary.org/obo/GO_7770110`

Added

Class: exit from cytosolic ribosome hibernation
exit from cytosolic ribosome hibernation term tracker item “https://github.com/geneontology/go-ontology/issues/32461”^^anyURI
exit from cytosolic ribosome hibernation created by “ai4c-agent”
exit from cytosolic ribosome hibernation creation date “2026-08-14T22:52:06Z”
exit from cytosolic ribosome hibernation has exact synonym “ribosome hibernation exit”
exit from cytosolic ribosome hibernation has exact synonym “translational restart after ribosome hibernation”
exit from cytosolic ribosome hibernation has_obo_namespace “biological_process”
exit from cytosolic ribosome hibernation has_related_synonym “ribosome reactivation”
exit from cytosolic ribosome hibernation id “GO:7770110”
exit from cytosolic ribosome hibernation definition “A cellular process that results in the reactivation of hibernating cytosolic ribosomes, enabling them to resume translation. Upon reversal of unfavorable conditions such as nutrient limitation, dedicated molecular machinery reactivates hibernating ribosomes and promotes recovery of active translation.”
- has cross-reference “PMID:32687489”
- has cross-reference “PMID:42129552”
exit from cytosolic ribosome hibernation label “exit from cytosolic ribosome hibernation”
exit from cytosolic ribosome hibernation SubClassOf positive regulation of cytoplasmic translation
exit from cytosolic ribosome hibernation SubClassOf in taxon some cellular organisms

extracellular microvesicle biogenesis `http://purl.obolibrary.org/obo/GO_0140113`

Removed

extracellular microvesicle biogenesis definition “The assembly and secretion of a set of components to form an extracellular microvesicule, a membrane-bounded vesicle that ranges in size 100 nm to 1 micron in size) and exits the cell by budding.”
- has cross-reference “PMID:28736435”

Added

extracellular microvesicle biogenesis definition “The assembly and secretion of a set of components to form an extracellular microvesicle, a membrane-bounded vesicle that ranges from 100 nm to 1 micron in size and exits the cell by budding.”
- has cross-reference “PMID:28736435”

extracellular vesicle biogenesis `http://purl.obolibrary.org/obo/GO_0140112`

Removed

extracellular vesicle biogenesis definition “The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.”
- has cross-reference “PMID:28736435”

Added

extracellular vesicle biogenesis definition “The assembly and secretion of a set of components to form an extracellular vesicle, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.”
- has cross-reference “PMID:28736435”

extrinsic component of phagophore membrane `http://purl.obolibrary.org/obo/GO_0097632`

Removed

extrinsic component of phagophore membrane has exact synonym “extrinsic to phagophore assembly site membrane”
extrinsic component of phagophore membrane has narrow synonym “extrinsic component of pre-autophagosomal structure membrane”
extrinsic component of phagophore membrane definition “The component of the phagophore assembly site membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.”
- has cross-reference “GOC:mf”
extrinsic component of phagophore membrane label “extrinsic component of phagophore assembly site membrane”
extrinsic component of phagophore membrane EquivalentTo extrinsic component of membrane and (part of some obsolete phagophore assembly site membrane)
extrinsic component of phagophore membrane SubClassOf extrinsic component of organelle membrane
extrinsic component of phagophore membrane SubClassOf part of some obsolete phagophore assembly site membrane

Added

extrinsic component of phagophore membrane term tracker item “https://github.com/geneontology/go-ontology/issues/29437”^^anyURI
extrinsic component of phagophore membrane has_related_synonym “extrinsic component of phagophore assembly site membrane”
extrinsic component of phagophore membrane has_related_synonym “extrinsic component of pre-autophagosomal structure membrane”
extrinsic component of phagophore membrane has_related_synonym “extrinsic to phagophore assembly site membrane”
extrinsic component of phagophore membrane definition “The component of a phagophore membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.”
- has cross-reference “GOC:mf”
extrinsic component of phagophore membrane label “extrinsic component of phagophore membrane”
extrinsic component of phagophore membrane EquivalentTo extrinsic component of membrane and (part of some phagophore membrane)
extrinsic component of phagophore membrane SubClassOf extrinsic component of membrane
extrinsic component of phagophore membrane SubClassOf part of some phagophore membrane

folate cycle `http://purl.obolibrary.org/obo/GO_0035999`

Removed

folate cycle has exact synonym “folate cycle”
folate cycle definition “The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesize other tetrahydrofolate molecules.”
- has cross-reference “GOC:yaf”
- has cross-reference “PMID:1825999”
folate cycle label “tetrahydrofolate interconversion”

Added

folate cycle term tracker item “https://github.com/geneontology/go-ontology/issues/32362”^^anyURI
folate cycle has exact synonym “folate-mediated one-carbon metabolism”
folate cycle has exact synonym “folic acid cycle”
folate cycle has exact synonym “tetrahydrofolate interconversion”
folate cycle definition “A cyclic series of interconversions of the one-carbon unit carried by tetrahydrofolate - as 10-formyltetrahydrofolate, 5,10-methenyltetrahydrofolate, 5,10-methylenetetrahydrofolate and 5-methyltetrahydrofolate. Couples the acquisition of a one-carbon unit from donors such as serine, glycine or formate with its transfer, in the appropriate oxidation state, to biosynthetic acceptors, and with regeneration of tetrahydrofolate.”
- has cross-reference “PMID:18804690”
- has cross-reference “PMID:1825999”
- has cross-reference “PMID:27641100”
folate cycle label “folate cycle”

formaldehyde assimilation `http://purl.obolibrary.org/obo/GO_0019649`

Added

formaldehyde assimilation SubClassOf nutrient assimilation

fructosamine biosynthetic process `http://purl.obolibrary.org/obo/GO_0030391`

Removed

fructosamine biosynthetic process SubClassOf obsolete fructosamine metabolic process

fructosamine catabolic process `http://purl.obolibrary.org/obo/GO_0030392`

Removed

fructosamine catabolic process SubClassOf obsolete fructosamine metabolic process

fructose 1,6-bisphosphate 1-phosphatase activity `http://purl.obolibrary.org/obo/GO_0042132`

Removed

fructose 1,6-bisphosphate 1-phosphatase activity has_broad_synonym “fructose-bisphosphatase activity”
- has cross-reference “EC:3.1.3.00”

Added

fructose 1,6-bisphosphate 1-phosphatase activity has_broad_synonym “fructose-bisphosphatase activity”
- has cross-reference “EC:3.1.3.11”

fructose export from vacuole to cytosol `http://purl.obolibrary.org/obo/GO_1902334`

Removed

fructose export from vacuole to cytosol label “fructose export from vacuole to cytoplasm”

Added

fructose export from vacuole to cytosol term tracker item “https://github.com/geneontology/go-ontology/issues/32419”^^anyURI
fructose export from vacuole to cytosol label “fructose export from vacuole to cytosol”

fructoselysine metabolic process `http://purl.obolibrary.org/obo/GO_0030393`

Removed

fructoselysine metabolic process SubClassOf obsolete fructosamine metabolic process

Added

fructoselysine metabolic process SubClassOf amino sugar metabolic process

gamma-1,2,3,4,5,6-hexachlorocyclohexane catabolic process `http://purl.obolibrary.org/obo/GO_0018919`

Removed

gamma-1,2,3,4,5,6-hexachlorocyclohexane catabolic process conformsTo metabolic_process.yaml

ganglioside biosynthetic process `http://purl.obolibrary.org/obo/GO_0001574`

Added

ganglioside biosynthetic process never in taxon Insecta
ganglioside biosynthetic process SubClassOf not (in taxon some Insecta)

ganglioside catabolic process `http://purl.obolibrary.org/obo/GO_0006689`

Added

ganglioside catabolic process never in taxon Insecta
ganglioside catabolic process SubClassOf not (in taxon some Insecta)

ganglioside metabolic process `http://purl.obolibrary.org/obo/GO_0001573`

Added

ganglioside metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32322”^^anyURI
ganglioside metabolic process never in taxon Insecta
ganglioside metabolic process SubClassOf not (in taxon some Insecta)

gap endonuclease activity `http://purl.obolibrary.org/obo/GO_0170076`

Added

Class: gap endonuclease activity
gap endonuclease activity term tracker item “https://github.com/geneontology/go-ontology/issues/32367”^^anyURI
gap endonuclease activity created by “ew”
gap endonuclease activity creation date “2026-08-10T17:51:18Z”
gap endonuclease activity has exact synonym “GEN activity”
gap endonuclease activity has exact synonym “Gap specific endonuclease activity”
gap endonuclease activity has_obo_namespace “molecular_function”
gap endonuclease activity id “GO:0170076”
gap endonuclease activity definition “Specific recognition and catalysis of the internal cleavage of the phosphodiester backbone within single-stranded DNA gaps or looped DNA structures at the junctions of single-stranded and double-stranded DNA. Primarily involved in the resolution of triplet repeat sequences, removal of aberrant secondary structures formed during the maturation of Okazaki fragments, telomeric R-loop resolution and the processing of stalled replication forks, that all involve cleavage at internal or branched DNA structures.”
- has cross-reference “PMID:15592449”
- has cross-reference “PMID:10330154”
gap endonuclease activity label “gap endonuclease activity”
gap endonuclease activity SubClassOf DNA endonuclease activity

glomerular basement membrane development `http://purl.obolibrary.org/obo/GO_0032836`

Removed

glomerular basement membrane development conformsTo anatomical_structure_development.yaml

glucose dehydrogenase (FAD, quinone) activity `http://purl.obolibrary.org/obo/GO_0140762`

Removed

glucose dehydrogenase (FAD, quinone) activity has cross-reference “MetaCyc:GLUCOSE-DEHYDROGENASE-ACCEPTOR-RXN”
glucose dehydrogenase (FAD, quinone) activity has cross-reference “RHEA:47372”
glucose dehydrogenase (FAD, quinone) activity exactMatch 47372
glucose dehydrogenase (FAD, quinone) activity definition “Catalysis of the reaction: a quinone + D-glucose = a quinol + D-glucono-1,5-lactone.”
- has cross-reference “RHEA:47372”
glucose dehydrogenase (FAD, quinone) activity SubClassOf has participant some 1,4-benzoquinones
glucose dehydrogenase (FAD, quinone) activity SubClassOf has participant some D-glucono-1,5-lactone
glucose dehydrogenase (FAD, quinone) activity SubClassOf has participant some hydroquinones
glucose dehydrogenase (FAD, quinone) activity SubClassOf has participant some D-glucopyranose

Added

glucose dehydrogenase (FAD, quinone) activity term tracker item “https://github.com/geneontology/go-ontology/issues/32504”^^anyURI
glucose dehydrogenase (FAD, quinone) activity broadMatch GLUCOSE-DEHYDROGENASE-ACCEPTOR-RXN
glucose dehydrogenase (FAD, quinone) activity broadMatch 47372
glucose dehydrogenase (FAD, quinone) activity broadMatch R00305
glucose dehydrogenase (FAD, quinone) activity definition “Catalysis of the reaction: D-glucose + a quinone = D-glucono-1,5-lactone + a quinol, using FAD as a cofactor.”
- has cross-reference “EC:1.1.5.9”
glucose dehydrogenase (FAD, quinone) activity has exact synonym “FAD-dependent glucose dehydrogenase activity”
- has cross-reference “EC:1.1.5.9”

glucose dehydrogenase (PQQ, quinone) activity `http://purl.obolibrary.org/obo/GO_0008876`

Removed

glucose dehydrogenase (PQQ, quinone) activity has cross-reference “KEGG_REACTION:R00305”
glucose dehydrogenase (PQQ, quinone) activity has cross-reference “MetaCyc:RXN0-6373”
glucose dehydrogenase (PQQ, quinone) activity has cross-reference “RHEA:22152”
glucose dehydrogenase (PQQ, quinone) activity exactMatch 22152
glucose dehydrogenase (PQQ, quinone) activity definition “Catalysis of the reaction: D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol.”
- has cross-reference “RHEA:22152”
glucose dehydrogenase (PQQ, quinone) activity label “quinoprotein glucose dehydrogenase activity”
glucose dehydrogenase (PQQ, quinone) activity SubClassOf has participant some D-glucono-1,5-lactone
glucose dehydrogenase (PQQ, quinone) activity SubClassOf has participant some ubiquinones
glucose dehydrogenase (PQQ, quinone) activity SubClassOf has participant some ubiquinol
glucose dehydrogenase (PQQ, quinone) activity SubClassOf has participant some D-glucopyranose

Added

glucose dehydrogenase (PQQ, quinone) activity term tracker item “https://github.com/geneontology/go-ontology/issues/32504”^^anyURI
glucose dehydrogenase (PQQ, quinone) activity has_broad_synonym “quinoprotein glucose dehydrogenase activity”
glucose dehydrogenase (PQQ, quinone) activity has exact synonym “quinoprotein glucose dehydrogenase (PQQ, quinone) activity”
glucose dehydrogenase (PQQ, quinone) activity broadMatch RXN0-6373
glucose dehydrogenase (PQQ, quinone) activity broadMatch 22152
glucose dehydrogenase (PQQ, quinone) activity broadMatch R06620
glucose dehydrogenase (PQQ, quinone) activity definition “Catalysis of the reaction: D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol, using PQQ as a cofactor.”
- has cross-reference “EC:1.1.5.2”
glucose dehydrogenase (PQQ, quinone) activity label “glucose dehydrogenase (PQQ, quinone) activity”

glutaredoxin-dependent peroxiredoxin activity `http://purl.obolibrary.org/obo/GO_7770099`

Added

Class: glutaredoxin-dependent peroxiredoxin activity
glutaredoxin-dependent peroxiredoxin activity term tracker item “https://github.com/geneontology/go-ontology/issues/32405”^^anyURI
glutaredoxin-dependent peroxiredoxin activity created by “ai4c-agent”
glutaredoxin-dependent peroxiredoxin activity creation date “2026-08-04T17:43:33Z”
glutaredoxin-dependent peroxiredoxin activity has cross-reference “EC:1.11.1.25”
glutaredoxin-dependent peroxiredoxin activity has cross-reference “RHEA:62624”
glutaredoxin-dependent peroxiredoxin activity has exact synonym “GrxPx activity”
glutaredoxin-dependent peroxiredoxin activity has_obo_namespace “molecular_function”
glutaredoxin-dependent peroxiredoxin activity has_related_synonym “thiol peroxidase activity”
glutaredoxin-dependent peroxiredoxin activity id “GO:7770099”
glutaredoxin-dependent peroxiredoxin activity exactMatch 1.11.1.25
glutaredoxin-dependent peroxiredoxin activity exactMatch 62624
glutaredoxin-dependent peroxiredoxin activity definition “Catalysis of the reaction: [glutaredoxin]-dithiol + a hydroperoxide = [glutaredoxin]-disulfide + an alcohol + H2O.”
- has cross-reference “RHEA:62624”
- has cross-reference “PMID:12517450”
- has cross-reference “PMID:11832487”
glutaredoxin-dependent peroxiredoxin activity label “glutaredoxin-dependent peroxiredoxin activity”
glutaredoxin-dependent peroxiredoxin activity SubClassOf peroxiredoxin activity
glutaredoxin-dependent peroxiredoxin activity SubClassOf has participant some water
glutaredoxin-dependent peroxiredoxin activity SubClassOf has participant some L-cysteine residue
glutaredoxin-dependent peroxiredoxin activity SubClassOf has participant some alcohol
glutaredoxin-dependent peroxiredoxin activity SubClassOf has participant some peroxol
glutaredoxin-dependent peroxiredoxin activity SubClassOf has participant some L-cystine residue

glutathione-dependent peroxiredoxin activity `http://purl.obolibrary.org/obo/GO_7770101`

Added

Class: glutathione-dependent peroxiredoxin activity
glutathione-dependent peroxiredoxin activity term tracker item “https://github.com/geneontology/go-ontology/issues/32405”^^anyURI
glutathione-dependent peroxiredoxin activity created by “ai4c-agent”
glutathione-dependent peroxiredoxin activity creation date “2026-08-04T17:43:33Z”
glutathione-dependent peroxiredoxin activity has cross-reference “EC:1.11.1.27”
glutathione-dependent peroxiredoxin activity has cross-reference “RHEA:62632”
glutathione-dependent peroxiredoxin activity has cross-reference “RHEA:69412”
glutathione-dependent peroxiredoxin activity has cross-reference “RHEA:69651”
glutathione-dependent peroxiredoxin activity has cross-reference “RHEA:76731”
glutathione-dependent peroxiredoxin activity has_obo_namespace “molecular_function”
glutathione-dependent peroxiredoxin activity has_related_synonym “thiol peroxidase activity”
glutathione-dependent peroxiredoxin activity id “GO:7770101”
glutathione-dependent peroxiredoxin activity exactMatch 1.11.1.27
glutathione-dependent peroxiredoxin activity exactMatch 62632
glutathione-dependent peroxiredoxin activity narrowMatch 69412
glutathione-dependent peroxiredoxin activity narrowMatch 69651
glutathione-dependent peroxiredoxin activity narrowMatch 76731
glutathione-dependent peroxiredoxin activity definition “Catalysis of the reaction: a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.”
- has cross-reference “PMID:12606554”
- has cross-reference “PMID:15004285”
- has cross-reference “RHEA:62632”
glutathione-dependent peroxiredoxin activity label “glutathione-dependent peroxiredoxin activity”
glutathione-dependent peroxiredoxin activity SubClassOf peroxidase activity
glutathione-dependent peroxiredoxin activity SubClassOf has participant some water
glutathione-dependent peroxiredoxin activity SubClassOf has participant some alcohol
glutathione-dependent peroxiredoxin activity SubClassOf has participant some peroxol
glutathione-dependent peroxiredoxin activity SubClassOf has participant some glutathionate(1-)
glutathione-dependent peroxiredoxin activity SubClassOf has participant some glutathione disulfide(2-)

glycerophospholipid flippase activity `http://purl.obolibrary.org/obo/GO_0140333`

Added

glycerophospholipid flippase activity conformsTo lipid_flippase_activity.yaml

glycine decarboxylation via glycine cleavage system `http://purl.obolibrary.org/obo/GO_0019464`

Removed

glycine decarboxylation via glycine cleavage system definition “The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.”
- has cross-reference “MetaCyc:GLYCLEAV-PWY”

Added

glycine decarboxylation via glycine cleavage system term tracker item “https://github.com/geneontology/go-ontology/issues/32362”^^anyURI
glycine decarboxylation via glycine cleavage system definition “The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.”
- has cross-reference “MetaCyc:GLYCLEAV-PWY”
- has cross-reference “PMID:36347252”
- has cross-reference “PMID:41521798”

glycolipid floppase activity `http://purl.obolibrary.org/obo/GO_0034202`

Added

glycolipid floppase activity conformsTo lipid_floppase_activity.yaml

glycolipid transfer activity `http://purl.obolibrary.org/obo/GO_0017089`

Added

glycolipid transfer activity conformsTo intermembrane_lipid_transfer_activity.yaml

glycolysis `http://purl.obolibrary.org/obo/GO_0006096`

Removed

glycolysis has_related_synonym “glycolysis”
- has cross-reference “GOC:dph”
glycolysis label “glycolytic process”

Added

glycolysis term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
glycolysis has cross-reference “MetaCyc:ANAGLYCOLYSIS-PWY”
glycolysis has cross-reference “MetaCyc:GLYCOLYSIS”
glycolysis has cross-reference “MetaCyc:PWY-1042”
glycolysis has cross-reference “MetaCyc:PWY-5484”
glycolysis has cross-reference “MetaCyc:PWY-8404”
glycolysis has exact synonym “glycolytic process”
glycolysis narrowMatch ANAGLYCOLYSIS-PWY
glycolysis narrowMatch GLYCOLYSIS
glycolysis narrowMatch PWY-1042
glycolysis narrowMatch PWY-5484
glycolysis narrowMatch PWY-8404
glycolysis label “glycolysis”

glycosylceramide flippase activity `http://purl.obolibrary.org/obo/GO_0140351`

Added

glycosylceramide flippase activity conformsTo lipid_flippase_activity.yaml

goslim_euk_cellular_processes_ribbon `http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon`

Removed

goslim_euk_cellular_processes_ribbon comment “GO ribbon for eukaroytic cellular processes”

Added

goslim_euk_cellular_processes_ribbon comment “GO ribbon for eukaryotic cellular processes”

granulocyte colony-stimulating factor receptor activity `http://purl.obolibrary.org/obo/GO_0004902`

Removed

granulocyte colony-stimulating factor receptor activity never in taxon Fungi
granulocyte colony-stimulating factor receptor activity SubClassOf not (in taxon some Fungi)

Added

granulocyte colony-stimulating factor receptor activity SubClassOf in taxon some [Vertebrata ](http://purl.obolibrary.org/obo/NCBITaxon_7742)

granulocyte colony-stimulating factor signaling pathway `http://purl.obolibrary.org/obo/GO_0038158`

Added

granulocyte colony-stimulating factor signaling pathway term tracker item “https://github.com/geneontology/go-ontology/issues/32373”^^anyURI
granulocyte colony-stimulating factor signaling pathway SubClassOf in taxon some [Vertebrata ](http://purl.obolibrary.org/obo/NCBITaxon_7742)

group translocator activity `http://purl.obolibrary.org/obo/GO_7770111`

Added

Class: group translocator activity
group translocator activity term tracker item “https://github.com/geneontology/go-ontology/issues/27496”^^anyURI
group translocator activity created by “ai4c-agent”
group translocator activity creation date “2026-08-18T00:41:26Z”
group translocator activity has cross-reference “TC:4”
group translocator activity has exact synonym “group translocation activity”
group translocator activity has_obo_namespace “molecular_function”
group translocator activity has_related_synonym “group translocator”
group translocator activity id “GO:7770111”
group translocator activity definition “Enables the transfer of a substance from one side of a membrane to the other, where the substance is chemically modified as an integral part of the translocation process, so that the species released on the far side of the membrane is not the species that was bound on the near side. This differs from primary and secondary active transport, in which the transported substance is unchanged.”
- has cross-reference “PMID:31214989”
- has cross-reference “PMID:33170213”
group translocator activity label “group translocator activity”
group translocator activity SubClassOf transmembrane transporter activity
group translocator activity SubClassOf has part some catalytic activity

heme A synthase activity `http://purl.obolibrary.org/obo/GO_0120547`

Removed

heme A synthase activity definition “Catalysis of the reaction: Fe(II)-heme o + 2 acceptor + H2O = Fe(II)-heme a + 2 acceptor-H2. The conversion of heme o to heme a occcurs by two successive hydroxylations of the methyl group at C8 using water as the oxygen source. The first hydroxylation forms heme i, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.”
- has cross-reference “RHEA:63388”
- has cross-reference “PMID:30397130”

Added

heme A synthase activity definition “Catalysis of the reaction: Fe(II)-heme o + 2 acceptor + H2O = Fe(II)-heme a + 2 acceptor-H2. The conversion of heme o to heme a occurs by two successive hydroxylations of the methyl group at C8 using water as the oxygen source. The first hydroxylation forms heme i, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.”
- has cross-reference “RHEA:63388”
- has cross-reference “PMID:30397130”

heme export from vacuole to cytosol `http://purl.obolibrary.org/obo/GO_0140357`

Removed

heme export from vacuole to cytosol label “heme export from vacuole to cytoplasm”

Added

heme export from vacuole to cytosol term tracker item “https://github.com/geneontology/go-ontology/issues/32419”^^anyURI
heme export from vacuole to cytosol label “heme export from vacuole to cytosol”

histamine secretion by basophil `http://purl.obolibrary.org/obo/GO_0002557`

Removed

histamine secretion by basophil EquivalentTo histamine secretion and (process has causal agent some basophil)
histamine secretion by basophil SubClassOf process has causal agent some basophil

Added

histamine secretion by basophil EquivalentTo histamine secretion and (occurs in some basophil)
histamine secretion by basophil SubClassOf occurs in some basophil

histamine secretion by mast cell `http://purl.obolibrary.org/obo/GO_0002553`

Removed

histamine secretion by mast cell EquivalentTo histamine secretion and (process has causal agent some mast cell)
histamine secretion by mast cell SubClassOf process has causal agent some mast cell

Added

histamine secretion by mast cell EquivalentTo histamine secretion and (occurs in some mast cell)
histamine secretion by mast cell SubClassOf occurs in some mast cell

histamine secretion by platelet `http://purl.obolibrary.org/obo/GO_0002555`

Removed

histamine secretion by platelet EquivalentTo histamine secretion and (process has causal agent some platelet)
histamine secretion by platelet SubClassOf process has causal agent some platelet

Added

histamine secretion by platelet EquivalentTo histamine secretion and (occurs in some platelet)
histamine secretion by platelet SubClassOf occurs in some platelet

host-mediated suppression of viral process `http://purl.obolibrary.org/obo/GO_0044793`

Removed

host-mediated suppression of viral process label “host-mediated suppression of viral proces”

Added

host-mediated suppression of viral process label “host-mediated suppression of viral process”

hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing) activity `http://purl.obolibrary.org/obo/GO_0043802`

Removed

hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing) activity label “hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity”

Added

hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing) activity label “hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing) activity”

imaginal disc-derived wing vein morphogenesis `http://purl.obolibrary.org/obo/GO_0008586`

Removed

imaginal disc-derived wing vein morphogenesis conformsTo anatomical_structure_morphogenesis.yaml

immaterial anatomical entity `http://purl.obolibrary.org/obo/UBERON_0000466`

Added

immaterial anatomical entity definition “Anatomical entity that has no mass.”

interleukin-5-mediated signaling pathway `http://purl.obolibrary.org/obo/GO_0038043`

Added

interleukin-5-mediated signaling pathway SubClassOf part of some cellular response to interleukin-5

interphotoreceptor matrix `http://purl.obolibrary.org/obo/GO_0033165`

Removed

interphotoreceptor matrix definition “A specialized extracellularc matrix that surrounds the photoreceptors of the retina and lies between them and the apical surface of the retinal pigment epithelium. The IPM has been implicated in several important activities required for photoreceptor function and maintenance.”
- has cross-reference “PMID:2194288”
- has cross-reference “PMID:1862095”

Added

interphotoreceptor matrix definition “A specialized extracellular matrix that surrounds the photoreceptors of the retina and lies between them and the apical surface of the retinal pigment epithelium. The IPM has been implicated in several important activities required for photoreceptor function and maintenance.”
- has cross-reference “PMID:2194288”
- has cross-reference “PMID:1862095”

intestinal enterochromaffin enteroendocrine cell differentiation `http://purl.obolibrary.org/obo/GO_7770020`

Added

intestinal enterochromaffin enteroendocrine cell differentiation conformsTo cell_differentiation_by_mature_cell_type.yaml

intestinal type G enteroendocrine cell differentiation `http://purl.obolibrary.org/obo/GO_7770021`

Added

intestinal type G enteroendocrine cell differentiation conformsTo cell_differentiation_by_mature_cell_type.yaml

intestinal type I enteroendocrine cell differentiation `http://purl.obolibrary.org/obo/GO_7770022`

Added

intestinal type I enteroendocrine cell differentiation conformsTo cell_differentiation_by_mature_cell_type.yaml

intestinal type L enteroendocrine cell differentiation `http://purl.obolibrary.org/obo/GO_7770023`

Added

intestinal type L enteroendocrine cell differentiation conformsTo cell_differentiation_by_mature_cell_type.yaml

intestinal type N enteroendocrine cell differentiation `http://purl.obolibrary.org/obo/GO_7770024`

Added

intestinal type N enteroendocrine cell differentiation conformsTo cell_differentiation_by_mature_cell_type.yaml

intracellular organelle lumen `http://purl.obolibrary.org/obo/GO_0070013`

Added

intracellular organelle lumen term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI
intracellular organelle lumen in_subset gocheck_do_not_annotate

inward rectifier potassium channel inhibitor activity `http://purl.obolibrary.org/obo/GO_0070320`

Removed

inward rectifier potassium channel inhibitor activity SubClassOf potassium channel inhibitor activity

Added

inward rectifier potassium channel inhibitor activity SubClassOf voltage-gated potassium channel inhibitor activity

iron chaperone activity `http://purl.obolibrary.org/obo/GO_0034986`

Added

iron chaperone activity conformsTo molecular_carrier_activity.yaml

iron-sulfur cluster chaperone activity `http://purl.obolibrary.org/obo/GO_0140132`

Added

iron-sulfur cluster chaperone activity conformsTo molecular_carrier_activity.yaml

large conductance calcium-activated potassium channel inhibitor activity `http://purl.obolibrary.org/obo/GO_7770089`

Added

Class: large conductance calcium-activated potassium channel inhibitor activity
large conductance calcium-activated potassium channel inhibitor activity term tracker item “https://github.com/geneontology/go-ontology/issues/32358”^^anyURI
large conductance calcium-activated potassium channel inhibitor activity created by “ai4c-agent”
large conductance calcium-activated potassium channel inhibitor activity creation date “2026-07-28T00:46:41Z”
large conductance calcium-activated potassium channel inhibitor activity has exact synonym “BK KCa channel inhibitor activity”
large conductance calcium-activated potassium channel inhibitor activity has exact synonym “BK calcium-activated potassium channel inhibitor activity”
large conductance calcium-activated potassium channel inhibitor activity has exact synonym “large conductance KCa channel inhibitor activity”
large conductance calcium-activated potassium channel inhibitor activity has_obo_namespace “molecular_function”
large conductance calcium-activated potassium channel inhibitor activity has_related_synonym “BK channel inhibitor activity”
large conductance calcium-activated potassium channel inhibitor activity id “GO:7770089”
large conductance calcium-activated potassium channel inhibitor activity definition “Binds to and stops, prevents, or reduces the activity of a large conductance calcium-activated potassium channel.”
- has cross-reference “PMID:17591990”
- has cross-reference “PMID:39971906”
large conductance calcium-activated potassium channel inhibitor activity label “large conductance calcium-activated potassium channel inhibitor activity”
large conductance calcium-activated potassium channel inhibitor activity EquivalentTo molecular function inhibitor activity and (directly negatively regulates some large conductance calcium-activated potassium channel activity)
large conductance calcium-activated potassium channel inhibitor activity SubClassOf potassium channel inhibitor activity
large conductance calcium-activated potassium channel inhibitor activity SubClassOf directly negatively regulates some large conductance calcium-activated potassium channel activity

larval heart development `http://purl.obolibrary.org/obo/GO_0007508`

Removed

larval heart development definition “The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “GOC:bf”

Added

larval heart development definition “The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodermal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “GOC:bf”

leukocyte mediated cytotoxicity `http://purl.obolibrary.org/obo/GO_0001909`

Removed

leukocyte mediated cytotoxicity comment “Note that this term and its children describe contact-dependent killing of target cells by lymphocytes and myeloid cells of the immune system.”
leukocyte mediated cytotoxicity EquivalentTo cell killing and (process has causal agent some leukocyte)

Added

leukocyte mediated cytotoxicity term tracker item “https://github.com/geneontology/go-ontology/issues/20574”^^anyURI
leukocyte mediated cytotoxicity comment “Note that this term and its children describe contact-dependent killing of target cells by lymphocytes and myeloid cells of the immune system. The is_a links to GO:0001906 and GO:0002443 are asserted rather than inferred because this term has no logical definition; they must be maintained by hand (see #20574).”

leukocyte mediated immunity `http://purl.obolibrary.org/obo/GO_0002443`

Removed

leukocyte mediated immunity EquivalentTo immune system process and (process has causal agent some leukocyte)

Added

leukocyte mediated immunity term tracker item “https://github.com/geneontology/go-ontology/issues/20574”^^anyURI
leukocyte mediated immunity comment “This term intentionally has no logical definition: it is a grouping class covering everything leukocytes do immunologically, and no relation in GO expresses that role as necessary and sufficient conditions. Subclasses must be asserted by hand (see #20574).”

lipid carrier activity `http://purl.obolibrary.org/obo/GO_0005319`

Added

lipid carrier activity conformsTo molecular_carrier_activity.yaml

lipoate synthase activity `http://purl.obolibrary.org/obo/GO_0016992`

Removed

lipoate synthase activity SubClassOf part of some obsolete lipoate biosynthetic process

Added

lipoate synthase activity SubClassOf part of some protein lipoylation

lipopolysaccharide floppase activity `http://purl.obolibrary.org/obo/GO_0015437`

Added

lipopolysaccharide floppase activity conformsTo lipid_floppase_activity.yaml

lipopolysaccharide transfer activity `http://purl.obolibrary.org/obo/GO_0140332`

Added

lipopolysaccharide transfer activity conformsTo intermembrane_lipid_transfer_activity.yaml

lipoprotein carrier activity `http://purl.obolibrary.org/obo/GO_0140598`

Added

lipoprotein carrier activity conformsTo molecular_carrier_activity.yaml

lipoyl-GcvH:protein N-lipoyltransferase activity `http://purl.obolibrary.org/obo/GO_7770091`

Added

Class: lipoyl-GcvH:protein N-lipoyltransferase activity
lipoyl-GcvH:protein N-lipoyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32361”^^anyURI
lipoyl-GcvH:protein N-lipoyltransferase activity created by “ai4c-agent”
lipoyl-GcvH:protein N-lipoyltransferase activity creation date “2026-07-28T20:08:06Z”
lipoyl-GcvH:protein N-lipoyltransferase activity has_broad_synonym “lipoyl amidotransferase activity”
lipoyl-GcvH:protein N-lipoyltransferase activity has cross-reference “EC:2.3.1.204”
lipoyl-GcvH:protein N-lipoyltransferase activity has cross-reference “RHEA:16413”
lipoyl-GcvH:protein N-lipoyltransferase activity has cross-reference “RHEA:20213”
lipoyl-GcvH:protein N-lipoyltransferase activity has_obo_namespace “molecular_function”
lipoyl-GcvH:protein N-lipoyltransferase activity has_related_synonym “lipoyl relay activity”
lipoyl-GcvH:protein N-lipoyltransferase activity has_related_synonym “octanoyl-[GcvH]:protein N-octanoyltransferase activity”
lipoyl-GcvH:protein N-lipoyltransferase activity id “GO:7770091”
lipoyl-GcvH:protein N-lipoyltransferase activity exactMatch 2.3.1.204
lipoyl-GcvH:protein N-lipoyltransferase activity narrowMatch 16413
lipoyl-GcvH:protein N-lipoyltransferase activity narrowMatch 20213
lipoyl-GcvH:protein N-lipoyltransferase activity definition “Catalysis of the reaction: N6-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + L-lysyl-[lipoyl-carrier protein] = L-lysyl-[glycine-cleavage complex H protein] + N6-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein].”
- has cross-reference “EC:2.3.1.204”
- has cross-reference “PMID:38624243”
lipoyl-GcvH:protein N-lipoyltransferase activity comment “The enzyme also transfers the biosynthetic precursor octanoyl group, and relays the acyl group from GcvH onto the E2 subunits of the pyruvate, 2-oxoglutarate, branched-chain 2-oxoacid and acetoin dehydrogenase complexes.”
lipoyl-GcvH:protein N-lipoyltransferase activity label “lipoyl-GcvH:protein N-lipoyltransferase activity”
lipoyl-GcvH:protein N-lipoyltransferase activity SubClassOf acyltransferase activity, transferring groups other than amino-acyl groups
lipoyl-GcvH:protein N-lipoyltransferase activity SubClassOf catalytic activity, acting on a protein

long-chain fatty acid omega-hydroxylase activity `http://purl.obolibrary.org/obo/GO_0102033`

Added

long-chain fatty acid omega-hydroxylase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32503”^^anyURI
long-chain fatty acid omega-hydroxylase activity has cross-reference “KEGG_REACTION:R07041”
long-chain fatty acid omega-hydroxylase activity has cross-reference “MetaCyc:RXN-19677”
long-chain fatty acid omega-hydroxylase activity has cross-reference “RHEA:39755”
long-chain fatty acid omega-hydroxylase activity narrowMatch RXN-19677
long-chain fatty acid omega-hydroxylase activity narrowMatch 39755
long-chain fatty acid omega-hydroxylase activity narrowMatch R07041

lymphocyte mediated immunity `http://purl.obolibrary.org/obo/GO_0002449`

Removed

lymphocyte mediated immunity EquivalentTo immune system process and (process has causal agent some lymphocyte)

lysophosphatidylcholine flippase activity `http://purl.obolibrary.org/obo/GO_0140348`

Added

lysophosphatidylcholine flippase activity conformsTo lipid_flippase_activity.yaml

mRNA m(6)A methyltransferase activity `http://purl.obolibrary.org/obo/GO_0001734`

Added

mRNA m(6)A methyltransferase activity SubClassOf RNA (adenine-N6)-methyltransferase activity

maintenance of seed dormancy by abscisic acid `http://purl.obolibrary.org/obo/GO_0098755`

Removed

maintenance of seed dormancy by abscisic acid definition “The process by which seed dormancy is maintained by the presence of absisic acid.”
- has cross-reference “PMID:9580097”
- has cross-reference “GOC:dos”
maintenance of seed dormancy by abscisic acid label “maintenance of seed dormancy by absisic acid”

Added

maintenance of seed dormancy by abscisic acid definition “The process by which seed dormancy is maintained by the presence of abscisic acid.”
- has cross-reference “PMID:9580097”
- has cross-reference “GOC:dos”
maintenance of seed dormancy by abscisic acid label “maintenance of seed dormancy by abscisic acid”

mannosyl-oligosaccharide 1,2-alpha-mannosidase complex `http://purl.obolibrary.org/obo/GO_0106055`

Removed

mannosyl-oligosaccharide 1,2-alpha-mannosidase complex definition “A protein complex capable of catalysing the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.”
- has cross-reference “PMID:21700223”
- has cross-reference “GOC:bhm”

Added

mannosyl-oligosaccharide 1,2-alpha-mannosidase complex definition “A protein complex capable of catalyzing the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.”
- has cross-reference “PMID:21700223”
- has cross-reference “GOC:bhm”

mast cell mediated immunity `http://purl.obolibrary.org/obo/GO_0002448`

Removed

mast cell mediated immunity EquivalentTo immune system process and (process has causal agent some mast cell)

material anatomical entity `http://purl.obolibrary.org/obo/UBERON_0000465`

Added

material anatomical entity definition “Anatomical entity that has mass.”

maternal determination of anterior/posterior axis, embryo `http://purl.obolibrary.org/obo/GO_0008358`

Removed

maternal determination of anterior/posterior axis, embryo definition “The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

maternal determination of anterior/posterior axis, embryo term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
maternal determination of anterior/posterior axis, embryo definition “The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos.”
- has cross-reference “ISBN:0879694238”

meiosis II cell cycle process `http://purl.obolibrary.org/obo/GO_0061983`

Removed

meiosis II cell cycle process definition “A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes.”
- has cross-reference “PMID:29385397”

Added

meiosis II cell cycle process definition “A process that contributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes.”
- has cross-reference “PMID:29385397”

meiotic metaphase I homologous chromosome alignment `http://purl.obolibrary.org/obo/GO_0043060`

Removed

meiotic metaphase I homologous chromosome alignment definition “A cell cycle process whereby homlogous chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator) by the spindle machinery and centromere/kinetochore arrangement during meiosis I chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.”
- has cross-reference “PMID:10809666”

Added

meiotic metaphase I homologous chromosome alignment definition “A cell cycle process whereby homologous chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator) by the spindle machinery and centromere/kinetochore arrangement during meiosis I chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.”
- has cross-reference “PMID:10809666”

membrane insertase activity `http://purl.obolibrary.org/obo/GO_0032977`

Removed

membrane insertase activity EquivalentTo molecular carrier activity and (part of some establishment of protein localization to membrane) and (has primary input some protein)
membrane insertase activity SubClassOf part of some establishment of protein localization to membrane

Added

membrane insertase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32404”^^anyURI

metallochaperone activity `http://purl.obolibrary.org/obo/GO_0016530`

Added

metallochaperone activity conformsTo molecular_carrier_activity.yaml

microglial cell mediated cytotoxicity `http://purl.obolibrary.org/obo/GO_0090634`

Removed

microglial cell mediated cytotoxicity EquivalentTo cell killing and (process has causal agent some microglial cell)

Added

microglial cell mediated cytotoxicity term tracker item “https://github.com/geneontology/go-ontology/issues/20574”^^anyURI
microglial cell mediated cytotoxicity comment “The is_a link to GO:0002444 is asserted rather than inferred because GO:0002444 has no logical definition; it must be maintained by hand (see #20574).”

microtubule polymerization based protein transport `http://purl.obolibrary.org/obo/GO_0099112`

Removed

microtubule polymerization based protein transport EquivalentTo intracellular transport and (has part some microtubule polymerization) and (process has causal agent some microtubule) and (has primary input some protein)

Added

microtubule polymerization based protein transport EquivalentTo intracellular transport and (has part some microtubule polymerization) and (has primary input some protein)

microtubule polymerization based protein transport to cell tip cortex `http://purl.obolibrary.org/obo/GO_0099110`

Removed

microtubule polymerization based protein transport to cell tip cortex EquivalentTo intracellular transport and (has part some microtubule polymerization) and (has target end location some cell cortex of cell tip) and (process has causal agent some microtubule) and (has primary input some protein)

Added

microtubule polymerization based protein transport to cell tip cortex EquivalentTo intracellular transport and (has part some microtubule polymerization) and (has target end location some cell cortex of cell tip) and (has primary input some protein)

microtubule-based process `http://purl.obolibrary.org/obo/GO_0007017`

Removed

microtubule-based process EquivalentTo cellular process and (process has causal agent some microtubule)

mitochondrial intermembrane space chaperone complex `http://purl.obolibrary.org/obo/GO_0042719`

Removed

mitochondrial intermembrane space chaperone complex has narrow synonym “Tim8-Tim13 complex”
mitochondrial intermembrane space chaperone complex has narrow synonym “Tim9-Tim10 complex”

Added

mitochondrial intermembrane space chaperone complex term tracker item “https://github.com/geneontology/go-ontology/issues/32408”^^anyURI

mitochondrial membrane organization `http://purl.obolibrary.org/obo/GO_0007006`

Removed

mitochondrial membrane organization conformsTo occursIn.yaml
mitochondrial membrane organization EquivalentTo membrane organization and (occurs in some mitochondrion)
mitochondrial membrane organization SubClassOf mitochondrion organization
mitochondrial membrane organization SubClassOf occurs in some mitochondrion

Added

mitochondrial membrane organization term tracker item “https://github.com/geneontology/go-ontology/issues/32356”^^anyURI
mitochondrial membrane organization EquivalentTo membrane organization and (results in organization of some mitochondrial membrane)
mitochondrial membrane organization SubClassOf part of some mitochondrion organization
mitochondrial membrane organization SubClassOf results in organization of some mitochondrial membrane

mitochondrial protein quality control `http://purl.obolibrary.org/obo/GO_0141164`

Removed

mitochondrial protein quality control definition “The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the mitochondrion, which are targeted for degradation.”
- has cross-reference “PMID:38280230”

Added

mitochondrial protein quality control term tracker item “https://github.com/geneontology/go-ontology/issues/32546”^^anyURI
mitochondrial protein quality control definition “The chemical reactions and pathways resulting in the breakdown of aberrant proteins in the mitochondrion which are targeted for degradation, including misfolded proteins and orphan subunits that fail to assemble into their cognate complex.”
- has cross-reference “PMID:7623837”
- has cross-reference “PMID:34436539”
- has cross-reference “PMID:38280230”
mitochondrial protein quality control SubClassOf protein catabolic process

molecular_function `http://purl.obolibrary.org/obo/GO_0003674`

Added

molecular_function definition “A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.”

momilactone-A synthase [NAD(P)H] activity `http://purl.obolibrary.org/obo/GO_0102960`

Removed

momilactone-A synthase [NAD(P)H] activity exactMatch 25363
momilactone-A synthase [NAD(P)H] activity SubClassOf has participant some hydron
momilactone-A synthase [NAD(P)H] activity SubClassOf has participant some momilactone A
momilactone-A synthase [NAD(P)H] activity SubClassOf has participant some 3beta-hydroxy-9beta-pimara-7,15-dien-19,6beta-olide
momilactone-A synthase [NAD(P)H] activity SubClassOf has participant some NAD(1-)
momilactone-A synthase [NAD(P)H] activity SubClassOf has participant some NADH(2-)

mycoredoxin-dependent peroxiredoxin activity `http://purl.obolibrary.org/obo/GO_7770100`

Added

Class: mycoredoxin-dependent peroxiredoxin activity
mycoredoxin-dependent peroxiredoxin activity term tracker item “https://github.com/geneontology/go-ontology/issues/32405”^^anyURI
mycoredoxin-dependent peroxiredoxin activity created by “ai4c-agent”
mycoredoxin-dependent peroxiredoxin activity creation date “2026-08-04T17:43:33Z”
mycoredoxin-dependent peroxiredoxin activity has cross-reference “EC:1.11.1.29”
mycoredoxin-dependent peroxiredoxin activity has cross-reference “RHEA:62640”
mycoredoxin-dependent peroxiredoxin activity has_obo_namespace “molecular_function”
mycoredoxin-dependent peroxiredoxin activity has_related_synonym “thiol peroxidase activity”
mycoredoxin-dependent peroxiredoxin activity id “GO:7770100”
mycoredoxin-dependent peroxiredoxin activity exactMatch 1.11.1.29
mycoredoxin-dependent peroxiredoxin activity exactMatch 62640
mycoredoxin-dependent peroxiredoxin activity definition “Catalysis of the reaction: [mycoredoxin]-dithiol + a hydroperoxide = [mycoredoxin]-disulfide + an alcohol + H2O.”
- has cross-reference “RHEA:62640”
- has cross-reference “PMID:24379404”
- has cross-reference “PMID:19737009”
mycoredoxin-dependent peroxiredoxin activity label “mycoredoxin-dependent peroxiredoxin activity”
mycoredoxin-dependent peroxiredoxin activity SubClassOf peroxiredoxin activity
mycoredoxin-dependent peroxiredoxin activity SubClassOf has participant some water
mycoredoxin-dependent peroxiredoxin activity SubClassOf has participant some L-cysteine residue
mycoredoxin-dependent peroxiredoxin activity SubClassOf has participant some alcohol
mycoredoxin-dependent peroxiredoxin activity SubClassOf has participant some peroxol
mycoredoxin-dependent peroxiredoxin activity SubClassOf has participant some L-cystine residue

myeloid dendritic cell cytokine production `http://purl.obolibrary.org/obo/GO_0002372`

Removed

myeloid dendritic cell cytokine production comment “Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the ‘regulation’ children terms.”
myeloid dendritic cell cytokine production EquivalentTo cytokine production and (process has causal agent some myeloid dendritic cell)
myeloid dendritic cell cytokine production SubClassOf process has causal agent some myeloid dendritic cell

Added

myeloid dendritic cell cytokine production term tracker item “https://github.com/geneontology/go-ontology/issues/20574”^^anyURI
myeloid dendritic cell cytokine production comment “Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the ‘regulation’ children terms. The is_a link to GO:0002444 is asserted rather than inferred because GO:0002444 has no logical definition; it must be maintained by hand (see #20574).”
myeloid dendritic cell cytokine production EquivalentTo cytokine production and (occurs in some myeloid dendritic cell)
myeloid dendritic cell cytokine production SubClassOf occurs in some myeloid dendritic cell

myeloid leukocyte mediated immunity `http://purl.obolibrary.org/obo/GO_0002444`

Removed

myeloid leukocyte mediated immunity EquivalentTo immune system process and (process has causal agent some myeloid leukocyte)

Added

myeloid leukocyte mediated immunity term tracker item “https://github.com/geneontology/go-ontology/issues/20574”^^anyURI
myeloid leukocyte mediated immunity comment “This term intentionally has no logical definition: it is a grouping class covering everything myeloid leukocytes do immunologically, and no relation in GO expresses that role as necessary and sufficient conditions. Subclasses must be asserted by hand (see #20574).”

myo-inositol export across plasma membrane `http://purl.obolibrary.org/obo/GO_7770109`

Added

Class: myo-inositol export across plasma membrane
myo-inositol export across plasma membrane term tracker item “https://github.com/geneontology/go-ontology/issues/32460”^^anyURI
myo-inositol export across plasma membrane conformsTo export_across_membrane.yaml
myo-inositol export across plasma membrane conformsTo import_across_membrane.yaml
myo-inositol export across plasma membrane created by “ai4c-agent”
myo-inositol export across plasma membrane creation date “2026-08-14T19:33:20Z”
myo-inositol export across plasma membrane has_broad_synonym “inositol export”
myo-inositol export across plasma membrane has_broad_synonym “myo-inositol export”
myo-inositol export across plasma membrane has exact synonym “myo-inositol export from cell”
myo-inositol export across plasma membrane has_obo_namespace “biological_process”
myo-inositol export across plasma membrane id “GO:7770109”
myo-inositol export across plasma membrane definition “The directed movement of myo-inositol from inside of a cell, across the plasma membrane and into the extracellular region.”
- has cross-reference “PMID:42567923”
myo-inositol export across plasma membrane label “myo-inositol export across plasma membrane”
myo-inositol export across plasma membrane EquivalentTo transport and (has target start location some cytosol) and (has target end location some extracellular region) and (results in transport across some plasma membrane) and (has primary input some myo-inositol)
myo-inositol export across plasma membrane SubClassOf polyol transmembrane transport
myo-inositol export across plasma membrane SubClassOf myo-inositol transport
myo-inositol export across plasma membrane SubClassOf export across plasma membrane

natural killer cell cytokine production `http://purl.obolibrary.org/obo/GO_0002370`

Removed

natural killer cell cytokine production EquivalentTo cytokine production and (process has causal agent some natural killer cell)

Added

natural killer cell cytokine production EquivalentTo cytokine production and (occurs in some natural killer cell)
natural killer cell cytokine production SubClassOf occurs in some natural killer cell

natural killer cell mediated cytotoxicity `http://purl.obolibrary.org/obo/GO_0042267`

Removed

natural killer cell mediated cytotoxicity EquivalentTo cell killing and (process has causal agent some natural killer cell)

natural killer cell mediated immune response to tumor cell `http://purl.obolibrary.org/obo/GO_0002423`

Removed

natural killer cell mediated immune response to tumor cell EquivalentTo immune response to tumor cell and (process has causal agent some natural killer cell)

natural killer cell mediated immunity `http://purl.obolibrary.org/obo/GO_0002228`

Removed

natural killer cell mediated immunity EquivalentTo immune system process and (process has causal agent some natural killer cell)

negative regulation of ‘de novo’ NAD biosynthetic process from L-tryptophan `http://purl.obolibrary.org/obo/GO_1905013`

Added

negative regulation of ERAD pathway `http://purl.obolibrary.org/obo/GO_1904293`

Removed

negative regulation of ERAD pathway SubClassOf negative regulation of response to endoplasmic reticulum stress

negative regulation of coenzyme A biosynthetic process `http://purl.obolibrary.org/obo/GO_0170077`

Added

Class: negative regulation of coenzyme A biosynthetic process
negative regulation of coenzyme A biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/32390”^^anyURI
negative regulation of coenzyme A biosynthetic process created by “ew”
negative regulation of coenzyme A biosynthetic process creation date “2026-08-10T18:46:59Z”
negative regulation of coenzyme A biosynthetic process has_obo_namespace “biological_process”
negative regulation of coenzyme A biosynthetic process id “GO:0170077”
negative regulation of coenzyme A biosynthetic process definition “Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of coenzyme A.”
- has cross-reference “PMID:42000723”
negative regulation of coenzyme A biosynthetic process label “negative regulation of coenzyme A biosynthetic process”
negative regulation of coenzyme A biosynthetic process SubClassOf regulation of coenzyme A biosynthetic process

negative regulation of cristae formation `http://purl.obolibrary.org/obo/GO_1903851`

Removed

negative regulation of cristae formation SubClassOf negative regulation of organelle organization

Added

negative regulation of cristae formation SubClassOf negative regulation of cellular component organization

negative regulation of glycolysis `http://purl.obolibrary.org/obo/GO_0045820`

Removed

negative regulation of glycolysis label “negative regulation of glycolytic process”

Added

negative regulation of glycolysis has exact synonym “negative regulation of glycolytic process”
negative regulation of glycolysis label “negative regulation of glycolysis”

negative regulation of mitochondrial respiratory chain complex I assembly `http://purl.obolibrary.org/obo/GO_7770120`

Added

Class: negative regulation of mitochondrial respiratory chain complex I assembly
negative regulation of mitochondrial respiratory chain complex I assembly term tracker item “https://github.com/geneontology/go-ontology/issues/32577”^^anyURI
negative regulation of mitochondrial respiratory chain complex I assembly never in taxon Schizosaccharomyces
negative regulation of mitochondrial respiratory chain complex I assembly never in taxon Saccharomyces
negative regulation of mitochondrial respiratory chain complex I assembly created by “ai4c-agent”
negative regulation of mitochondrial respiratory chain complex I assembly creation date “2026-09-11T00:23:26Z”
negative regulation of mitochondrial respiratory chain complex I assembly has_obo_namespace “biological_process”
negative regulation of mitochondrial respiratory chain complex I assembly id “GO:7770120”
negative regulation of mitochondrial respiratory chain complex I assembly definition “Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial respiratory chain complex I assembly.”
- has cross-reference “PMID:42361792”
negative regulation of mitochondrial respiratory chain complex I assembly label “negative regulation of mitochondrial respiratory chain complex I assembly”
negative regulation of mitochondrial respiratory chain complex I assembly EquivalentTo biological regulation and (negatively regulates some mitochondrial respiratory chain complex I assembly)
negative regulation of mitochondrial respiratory chain complex I assembly SubClassOf negative regulation of protein-containing complex assembly
negative regulation of mitochondrial respiratory chain complex I assembly SubClassOf regulation of mitochondrial respiratory chain complex I assembly
negative regulation of mitochondrial respiratory chain complex I assembly SubClassOf not (in taxon some Schizosaccharomyces)
negative regulation of mitochondrial respiratory chain complex I assembly SubClassOf not (in taxon some Saccharomyces)
negative regulation of mitochondrial respiratory chain complex I assembly SubClassOf negatively regulates some mitochondrial respiratory chain complex I assembly

negative regulation of nuclear-transcribed mRNA catabolic process, no-go decay `http://purl.obolibrary.org/obo/GO_0170075`

Removed

negative regulation of nuclear-transcribed mRNA catabolic process, no-go decay label “negative regluation of nuclear-transribed mRNA catabolic process, no-go decay”

Added

negative regulation of nuclear-transcribed mRNA catabolic process, no-go decay label “negative regulation of nuclear-transcribed mRNA catabolic process, no-go decay”

negative regulation of protein processing in phagocytic vesicle `http://purl.obolibrary.org/obo/GO_1903922`

Added

negative regulation of protein processing in phagocytic vesicle never in taxon Fungi
negative regulation of protein processing in phagocytic vesicle SubClassOf not (in taxon some Fungi)

negative regulation of tight junction disassembly `http://purl.obolibrary.org/obo/GO_1905074`

Added

negative regulation of tight junction disassembly never in taxon Fungi
negative regulation of tight junction disassembly SubClassOf not (in taxon some Fungi)

negative regulation of vesicle fusion with Golgi apparatus `http://purl.obolibrary.org/obo/GO_0106215`

Removed

negative regulation of vesicle fusion with Golgi apparatus definition “Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus.”
- has cross-reference “PMID:26195667”
- has cross-reference “GOC:se”

Added

negative regulation of vesicle fusion with Golgi apparatus definition “Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fusion with Golgi apparatus.”
- has cross-reference “PMID:26195667”
- has cross-reference “GOC:se”

neurotransmitter receptor transport, postsynaptic endosome to lysosome `http://purl.obolibrary.org/obo/GO_0098943`

Removed

neurotransmitter receptor transport, postsynaptic endosome to lysosome definition “The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation.”
- has cross-reference “GOC:dos”

Added

neurotransmitter receptor transport, postsynaptic endosome to lysosome definition “The directed movement of neurotransmitter receptor from the postsynaptic endosome in transport vesicles to the lysosome for degradation.”
- has cross-reference “GOC:dos”

neutrophil mediated cytotoxicity `http://purl.obolibrary.org/obo/GO_0070942`

Removed

neutrophil mediated cytotoxicity EquivalentTo cell killing and (process has causal agent some neutrophil)

neutrophil mediated immunity `http://purl.obolibrary.org/obo/GO_0002446`

Removed

neutrophil mediated immunity EquivalentTo immune system process and (process has causal agent some neutrophil)

nickel chaperone activity `http://purl.obolibrary.org/obo/GO_0170061`

Added

nickel chaperone activity conformsTo molecular_carrier_activity.yaml

nitrate assimilation `http://purl.obolibrary.org/obo/GO_0042128`

Added

nitrate assimilation term tracker item “https://github.com/geneontology/go-ontology/issues/32376”^^anyURI
nitrate assimilation SubClassOf nutrient assimilation

noctua_allowed `http://purl.obolibrary.org/obo/go#noctua_allowed`

Added

AnnotationProperty: noctua_allowed
noctua_allowed comment “ChEBI terms allowed for use in Noctua, comprising the Rhea pH 7.3 subset and the GO ChEBI allow-list.”
noctua_allowed SubPropertyOf: subset_property

nuclear protein quality control by the ubiquitin-proteasome system `http://purl.obolibrary.org/obo/GO_0071630`

Removed

nuclear protein quality control by the ubiquitin-proteasome system SubClassOf part of some cellular response to misfolded protein

Added

nuclear protein quality control by the ubiquitin-proteasome system term tracker item “https://github.com/geneontology/go-ontology/issues/32546”^^anyURI

nucleocytoplasmic carrier activity `http://purl.obolibrary.org/obo/GO_0140142`

Added

nucleocytoplasmic carrier activity conformsTo molecular_carrier_activity_by_process.yaml

nutrient assimilation `http://purl.obolibrary.org/obo/GO_7770097`

Added

Class: nutrient assimilation
nutrient assimilation term tracker item “https://github.com/geneontology/go-ontology/issues/32376”^^anyURI
nutrient assimilation created by “ai4c-agent”
nutrient assimilation creation date “2026-07-29T05:36:39Z”
nutrient assimilation has exact synonym “assimilation of nutrients”
nutrient assimilation has_obo_namespace “biological_process”
nutrient assimilation id “GO:7770097”
nutrient assimilation in_subset gocheck_do_not_annotate
nutrient assimilation definition “The chemical reactions and pathways by which a cell or organism takes up a nutrient from its environment and incorporates it into cellular constituents, characteristically converting a simple, usually inorganic, nutrient source such as nitrate, sulfate, ammonia or a one-carbon compound into organic constituents of the cell.”
- has cross-reference “PMID:27572125”
- has cross-reference “PMID:34973427”
- has cross-reference “PMID:22103536”
nutrient assimilation label “nutrient assimilation”
nutrient assimilation SubClassOf metabolic process

obsolete (1->3)-alpha-glucan metabolic process `http://purl.obolibrary.org/obo/GO_0070595`

Removed

obsolete (1->3)-alpha-glucan metabolic process conformsTo metabolic_process.yaml

obsolete (1->4)-alpha-glucan metabolic process `http://purl.obolibrary.org/obo/GO_0070629`

Removed

obsolete (1->4)-alpha-glucan metabolic process conformsTo metabolic_process.yaml

obsolete (Z)-nonadeca-1,14-diene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900879`

Removed

obsolete (Z)-nonadeca-1,14-diene biosynthetic process conformsTo biosynthetic_process.yaml

obsolete (Z)-nonadeca-1,14-diene metabolic process `http://purl.obolibrary.org/obo/GO_1900878`

Removed

obsolete (Z)-nonadeca-1,14-diene metabolic process conformsTo metabolic_process.yaml

obsolete 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process `http://purl.obolibrary.org/obo/GO_0018977`

Removed

obsolete 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process conformsTo metabolic_process.yaml

obsolete 1,2,3-tribromopropane metabolic process `http://purl.obolibrary.org/obo/GO_0018976`

Removed

obsolete 1,2,3-tribromopropane metabolic process conformsTo metabolic_process.yaml

obsolete 1,3-dichloropropene metabolic process `http://purl.obolibrary.org/obo/GO_0018903`

Removed

obsolete 1,3-dichloropropene metabolic process conformsTo metabolic_process.yaml

obsolete 10-formyltetrahydrofolate biosynthetic process `http://purl.obolibrary.org/obo/GO_0009257`

Removed

obsolete 10-formyltetrahydrofolate biosynthetic process conformsTo biosynthetic_process.yaml
obsolete 10-formyltetrahydrofolate biosynthetic process definition “The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.”
- has cross-reference “GOC:ai”
obsolete 10-formyltetrahydrofolate biosynthetic process label “10-formyltetrahydrofolate biosynthetic process”
obsolete 10-formyltetrahydrofolate biosynthetic process EquivalentTo biosynthetic process and (has primary output some 10-formyltetrahydrofolate(2-))
obsolete 10-formyltetrahydrofolate biosynthetic process SubClassOf 10-formyltetrahydrofolate metabolic process
obsolete 10-formyltetrahydrofolate biosynthetic process SubClassOf dicarboxylic acid biosynthetic process
obsolete 10-formyltetrahydrofolate biosynthetic process SubClassOf tetrahydrofolate biosynthetic process
obsolete 10-formyltetrahydrofolate biosynthetic process SubClassOf has primary output some 10-formyltetrahydrofolate(2-)

Added

obsolete 10-formyltetrahydrofolate biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/32289”^^anyURI
obsolete 10-formyltetrahydrofolate biosynthetic process term replaced by folate cycle
obsolete 10-formyltetrahydrofolate biosynthetic process definition “OBSOLETE. The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.”
- has cross-reference “GOC:ai”
obsolete 10-formyltetrahydrofolate biosynthetic process deprecated true
obsolete 10-formyltetrahydrofolate biosynthetic process comment “This term was obsoleted because it represents the same process as folate cycle ; GO:0035999.”
obsolete 10-formyltetrahydrofolate biosynthetic process label “obsolete 10-formyltetrahydrofolate biosynthetic process”

obsolete 17-methylnonadec-1-ene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900883`

Removed

obsolete 17-methylnonadec-1-ene biosynthetic process conformsTo biosynthetic_process.yaml

obsolete 17-methylnonadec-1-ene metabolic process `http://purl.obolibrary.org/obo/GO_1900882`

Removed

obsolete 17-methylnonadec-1-ene metabolic process conformsTo metabolic_process.yaml

obsolete 18-methylnonadec-1-ene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900881`

Removed

obsolete 18-methylnonadec-1-ene biosynthetic process conformsTo biosynthetic_process.yaml

obsolete 18-methylnonadec-1-ene metabolic process `http://purl.obolibrary.org/obo/GO_1900880`

Removed

obsolete 18-methylnonadec-1-ene metabolic process conformsTo metabolic_process.yaml

obsolete 3-chloroacrylic acid metabolic process `http://purl.obolibrary.org/obo/GO_0018888`

Removed

obsolete 3-chloroacrylic acid metabolic process conformsTo metabolic_process.yaml

obsolete 3-hydroxybenzyl alcohol metabolic process `http://purl.obolibrary.org/obo/GO_0018921`

Removed

obsolete 3-hydroxybenzyl alcohol metabolic process conformsTo metabolic_process.yaml

obsolete 4-carboxy-4’-sulfoazobenzene metabolic process `http://purl.obolibrary.org/obo/GO_0018887`

Removed

obsolete 4-carboxy-4’-sulfoazobenzene metabolic process conformsTo metabolic_process.yaml

obsolete 4-chlorobenzoate dehalogenase activity `http://purl.obolibrary.org/obo/GO_0047576`

Removed

obsolete 4-chlorobenzoate dehalogenase activity has cross-reference “EC:3.8.1.6”
obsolete 4-chlorobenzoate dehalogenase activity has cross-reference “KEGG_REACTION:R01307”
obsolete 4-chlorobenzoate dehalogenase activity has cross-reference “MetaCyc:4-CHLOROBENZOATE-DEHALOGENASE-RXN”
obsolete 4-chlorobenzoate dehalogenase activity has cross-reference “RHEA:23440”
obsolete 4-chlorobenzoate dehalogenase activity exactMatch 3.8.1.6
obsolete 4-chlorobenzoate dehalogenase activity exactMatch 23440
obsolete 4-chlorobenzoate dehalogenase activity definition “Catalysis of the reaction: 4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride + H+.”
- has cross-reference “RHEA:23440”
obsolete 4-chlorobenzoate dehalogenase activity label “4-chlorobenzoate dehalogenase activity”
obsolete 4-chlorobenzoate dehalogenase activity SubClassOf hydrolase activity, acting on halide bonds, in C-halide compounds
obsolete 4-chlorobenzoate dehalogenase activity SubClassOf has participant some water
obsolete 4-chlorobenzoate dehalogenase activity SubClassOf has participant some hydron
obsolete 4-chlorobenzoate dehalogenase activity SubClassOf has participant some 4-chlorobenzoate
obsolete 4-chlorobenzoate dehalogenase activity SubClassOf has participant some 4-hydroxybenzoate
obsolete 4-chlorobenzoate dehalogenase activity SubClassOf has participant some chloride

Added

obsolete 4-chlorobenzoate dehalogenase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32542”^^anyURI
obsolete 4-chlorobenzoate dehalogenase activity consider 4-hydroxybenzoyl-CoA thioesterase activity
obsolete 4-chlorobenzoate dehalogenase activity consider 4-chlorobenzoyl-CoA dehalogenase activity
obsolete 4-chlorobenzoate dehalogenase activity consider 4-chlorobenzoate-CoA ligase activity
obsolete 4-chlorobenzoate dehalogenase activity definition “OBSOLETE. Catalysis of the reaction: 4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride + H+.”
- has cross-reference “RHEA:23440”
obsolete 4-chlorobenzoate dehalogenase activity deprecated true
obsolete 4-chlorobenzoate dehalogenase activity comment “The reason for obsoletion is that this activity is not known to be catalyzed by any gene product, there is no evidence that this function/process/component exists, and the EC number (EC 3.8.1.6) on which this GO term was based has been deleted in the IUBMB EC list.”
obsolete 4-chlorobenzoate dehalogenase activity label “obsolete 4-chlorobenzoate dehalogenase activity”

obsolete 7-cyano-7-deazaguanine metabolic process `http://purl.obolibrary.org/obo/GO_0097287`

Removed

obsolete 7-cyano-7-deazaguanine metabolic process conformsTo metabolic_process.yaml

obsolete D-glucosamine metabolic process `http://purl.obolibrary.org/obo/GO_0006041`

Removed

obsolete D-glucosamine metabolic process conformsTo metabolic_process.yaml
obsolete D-glucosamine metabolic process definition “The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.”
- has cross-reference “ISBN:0198506732”
- has cross-reference “GOC:jl”
obsolete D-glucosamine metabolic process label “D-glucosamine metabolic process”
obsolete D-glucosamine metabolic process EquivalentTo metabolic process and (has primary input or output some 2-ammonio-2-deoxy-D-glucopyranose)
obsolete D-glucosamine metabolic process SubClassOf amino sugar metabolic process
obsolete D-glucosamine metabolic process SubClassOf has primary input or output some 2-ammonio-2-deoxy-D-glucopyranose

Added

obsolete D-glucosamine metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32273”^^anyURI
obsolete D-glucosamine metabolic process consider D-glucosamine biosynthetic process
obsolete D-glucosamine metabolic process consider D-glucosamine catabolic process
obsolete D-glucosamine metabolic process definition “OBSOLETE. The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.”
- has cross-reference “ISBN:0198506732”
- has cross-reference “GOC:jl”
obsolete D-glucosamine metabolic process deprecated true
obsolete D-glucosamine metabolic process comment “The reason for obsoletion is that these terms were added in error.”
obsolete D-glucosamine metabolic process label “obsolete D-glucosamine metabolic process”

obsolete DNA ADP-ribosylation `http://purl.obolibrary.org/obo/GO_0030592`

Removed

obsolete DNA ADP-ribosylation definition “The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA.”
- has cross-reference “PMID:29361132”
- has cross-reference “PMID:27471034”
- has cross-reference “PMID:29520010”
- has cross-reference “PMID:11592983”
obsolete DNA ADP-ribosylation label “DNA ADP-ribosylation”
obsolete DNA ADP-ribosylation SubClassOf DNA modification

Added

obsolete DNA ADP-ribosylation term tracker item “https://github.com/geneontology/go-ontology/issues/32538”^^anyURI
obsolete DNA ADP-ribosylation consider NAD DNA ADP-ribosyltransferase activity
obsolete DNA ADP-ribosylation definition “OBSOLETE. The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA.”
- has cross-reference “PMID:29361132”
- has cross-reference “PMID:27471034”
- has cross-reference “PMID:29520010”
- has cross-reference “PMID:11592983”
obsolete DNA ADP-ribosylation deprecated true
obsolete DNA ADP-ribosylation comment “This term was obsoleted because it represents a molecular function.”
obsolete DNA ADP-ribosylation label “obsolete DNA ADP-ribosylation”

obsolete FADH2 metabolic process `http://purl.obolibrary.org/obo/GO_0006746`

Removed

obsolete FADH2 metabolic process conformsTo metabolic_process.yaml

obsolete K antigen metabolic process `http://purl.obolibrary.org/obo/GO_0046375`

Removed

obsolete K antigen metabolic process conformsTo metabolic_process.yaml

obsolete N-acetylglucosamine metabolic process `http://purl.obolibrary.org/obo/GO_0006044`

Removed

obsolete N-acetylglucosamine metabolic process conformsTo metabolic_process.yaml
obsolete N-acetylglucosamine metabolic process definition “The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.”
- has cross-reference “ISBN:0198506732”
obsolete N-acetylglucosamine metabolic process label “N-acetylglucosamine metabolic process”
obsolete N-acetylglucosamine metabolic process EquivalentTo metabolic process and (has primary input or output some N-acetyl-D-glucosamine)
obsolete N-acetylglucosamine metabolic process SubClassOf amino sugar metabolic process
obsolete N-acetylglucosamine metabolic process SubClassOf has primary input or output some N-acetyl-D-glucosamine

Added

obsolete N-acetylglucosamine metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32273”^^anyURI
obsolete N-acetylglucosamine metabolic process consider N-acetylglucosamine biosynthetic process
obsolete N-acetylglucosamine metabolic process consider N-acetylglucosamine catabolic process
obsolete N-acetylglucosamine metabolic process definition “OBSOLETE. The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.”
- has cross-reference “ISBN:0198506732”
obsolete N-acetylglucosamine metabolic process deprecated true
obsolete N-acetylglucosamine metabolic process comment “The reason for obsoletion is that this term was made in error and is an unnecessary grouping term.”
obsolete N-acetylglucosamine metabolic process label “obsolete N-acetylglucosamine metabolic process”

obsolete N-acetylmannosamine metabolic process `http://purl.obolibrary.org/obo/GO_0006051`

Removed

obsolete N-acetylmannosamine metabolic process conformsTo metabolic_process.yaml
obsolete N-acetylmannosamine metabolic process definition “The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.”
- has cross-reference “GOC:ai”
- has cross-reference “ISBN:0198506732”
obsolete N-acetylmannosamine metabolic process label “N-acetylmannosamine metabolic process”
obsolete N-acetylmannosamine metabolic process EquivalentTo metabolic process and (has primary input or output some N-acetylmannosamine)
obsolete N-acetylmannosamine metabolic process SubClassOf amino sugar metabolic process
obsolete N-acetylmannosamine metabolic process SubClassOf has primary input or output some N-acetylmannosamine

Added

obsolete N-acetylmannosamine metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32273”^^anyURI
obsolete N-acetylmannosamine metabolic process consider N-acetylmannosamine biosynthetic process
obsolete N-acetylmannosamine metabolic process consider N-acetylmannosamine catabolic process
obsolete N-acetylmannosamine metabolic process definition “OBSOLETE. The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.”
- has cross-reference “GOC:ai”
- has cross-reference “ISBN:0198506732”
obsolete N-acetylmannosamine metabolic process deprecated true
obsolete N-acetylmannosamine metabolic process comment “The reason for obsoletion is that this term was made in error and is an unnecessary grouping term.”
obsolete N-acetylmannosamine metabolic process label “obsolete N-acetylmannosamine metabolic process”

obsolete N-acetylneuraminate metabolic process `http://purl.obolibrary.org/obo/GO_0006054`

Removed

obsolete N-acetylneuraminate metabolic process conformsTo metabolic_process.yaml
obsolete N-acetylneuraminate metabolic process definition “The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.”
- has cross-reference “ISBN:0198506732”
obsolete N-acetylneuraminate metabolic process label “N-acetylneuraminate metabolic process”
obsolete N-acetylneuraminate metabolic process EquivalentTo metabolic process and (has primary input or output some N-acetylneuraminate)
obsolete N-acetylneuraminate metabolic process SubClassOf amino sugar metabolic process
obsolete N-acetylneuraminate metabolic process SubClassOf carboxylic acid metabolic process
obsolete N-acetylneuraminate metabolic process SubClassOf has primary input or output some N-acetylneuraminate

Added

obsolete N-acetylneuraminate metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32273”^^anyURI
obsolete N-acetylneuraminate metabolic process consider N-acetylneuraminate catabolic process
obsolete N-acetylneuraminate metabolic process consider N-acetylneuraminate biosynthetic process
obsolete N-acetylneuraminate metabolic process definition “OBSOLETE. The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.”
- has cross-reference “ISBN:0198506732”
obsolete N-acetylneuraminate metabolic process deprecated true
obsolete N-acetylneuraminate metabolic process comment “The reason for obsoletion is that this term was made in error and is an unnecessary grouping term.”
obsolete N-acetylneuraminate metabolic process label “obsolete N-acetylneuraminate metabolic process”

obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity `http://purl.obolibrary.org/obo/GO_0030701`

Removed

obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity has cross-reference “EC:2.4.2.37”
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity has cross-reference “MetaCyc:2.4.2.37-RXN”
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity has cross-reference “RHEA:18077”
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity exactMatch 2.4.2.37
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity exactMatch 18077
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity definition “Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase].”
- has cross-reference “EC:2.4.2.37”
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity label “NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity”
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity SubClassOf pentosyltransferase activity
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity SubClassOf has participant some hydron
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity SubClassOf has participant some nicotinamide
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity SubClassOf has participant some L-argininium residue
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity SubClassOf has participant some NAD(1-)
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity SubClassOf has participant some N(omega)-alpha-(ADP-D-ribosyl)-L-arginine(1-) residue

Added

obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32501”^^anyURI
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32503”^^anyURI
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity term replaced by NAD+-protein-arginine ADP-ribosyltransferase activity
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity definition “OBSOLETE. Catalysis of the reaction: L-arginyl-[dinitrogen reductase] + NAD+ = N(omega)-alpha-(ADP-D-ribosyl)-L-arginyl-[dinitrogen reductase] + nicotinamide + H+.”
- has cross-reference “RHEA:18077”
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity deprecated true
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity comment “The reason for obsoletion is that this term represents a specific substrate of the parent GO:0106274 NAD+-protein-arginine ADP-ribosyltransferase activity.”
obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity label “obsolete NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity”

obsolete UDP-N-acetylgalactosamine metabolic process `http://purl.obolibrary.org/obo/GO_0019276`

Removed

obsolete UDP-N-acetylgalactosamine metabolic process conformsTo metabolic_process.yaml
obsolete UDP-N-acetylgalactosamine metabolic process definition “The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.”
- has cross-reference “GOC:ai”
obsolete UDP-N-acetylgalactosamine metabolic process label “UDP-N-acetylgalactosamine metabolic process”
obsolete UDP-N-acetylgalactosamine metabolic process EquivalentTo metabolic process and (has primary input or output some UDP-N-acetyl-D-galactosamine(2-))
obsolete UDP-N-acetylgalactosamine metabolic process SubClassOf amino sugar metabolic process
obsolete UDP-N-acetylgalactosamine metabolic process SubClassOf nucleotide-sugar metabolic process
obsolete UDP-N-acetylgalactosamine metabolic process SubClassOf has primary input or output some UDP-N-acetyl-D-galactosamine(2-)

Added

obsolete UDP-N-acetylgalactosamine metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32273”^^anyURI
obsolete UDP-N-acetylgalactosamine metabolic process consider UDP-N-acetylgalactosamine biosynthetic process
obsolete UDP-N-acetylgalactosamine metabolic process definition “OBSOLETE. The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.”
- has cross-reference “GOC:ai”
obsolete UDP-N-acetylgalactosamine metabolic process deprecated true
obsolete UDP-N-acetylgalactosamine metabolic process comment “The reason for obsoletion is that this term was made in error and is an unnecessary grouping term.”
obsolete UDP-N-acetylgalactosamine metabolic process label “obsolete UDP-N-acetylgalactosamine metabolic process”

obsolete UDP-N-acetylglucosamine metabolic process `http://purl.obolibrary.org/obo/GO_0006047`

Removed

obsolete UDP-N-acetylglucosamine metabolic process conformsTo metabolic_process.yaml
obsolete UDP-N-acetylglucosamine metabolic process definition “The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.”
- has cross-reference “GOC:ai”
obsolete UDP-N-acetylglucosamine metabolic process label “UDP-N-acetylglucosamine metabolic process”
obsolete UDP-N-acetylglucosamine metabolic process EquivalentTo metabolic process and (has primary input or output some UDP-N-acetyl-alpha-D-glucosamine(2-))
obsolete UDP-N-acetylglucosamine metabolic process SubClassOf amino sugar metabolic process
obsolete UDP-N-acetylglucosamine metabolic process SubClassOf nucleotide-sugar metabolic process
obsolete UDP-N-acetylglucosamine metabolic process SubClassOf has primary input or output some UDP-N-acetyl-alpha-D-glucosamine(2-)

Added

obsolete UDP-N-acetylglucosamine metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32273”^^anyURI
obsolete UDP-N-acetylglucosamine metabolic process consider UDP-N-acetylglucosamine biosynthetic process
obsolete UDP-N-acetylglucosamine metabolic process definition “OBSOLETE. The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.”
- has cross-reference “GOC:ai”
obsolete UDP-N-acetylglucosamine metabolic process deprecated true
obsolete UDP-N-acetylglucosamine metabolic process comment “The reason for obsoletion is that this term was made in error and is an unnecessary grouping term.”
obsolete UDP-N-acetylglucosamine metabolic process label “obsolete UDP-N-acetylglucosamine metabolic process”

obsolete alanyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006419`

Removed

obsolete alanyl-tRNA aminoacylation definition “The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3’-OH group of an alanine accetping tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete alanyl-tRNA aminoacylation label “alanyl-tRNA aminoacylation”
obsolete alanyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete alanyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete alanyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete alanyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete alanyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3’-OH group of an alanine accetping tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete alanyl-tRNA aminoacylation deprecated true
obsolete alanyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004813 alanine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete alanyl-tRNA aminoacylation label “obsolete alanyl-tRNA aminoacylation”

obsolete aldoxime metabolic process `http://purl.obolibrary.org/obo/GO_0019330`

Removed

obsolete aldoxime metabolic process conformsTo metabolic_process.yaml

obsolete all-trans undecaprenol kinase activity `http://purl.obolibrary.org/obo/GO_0036432`

Removed

obsolete all-trans undecaprenol kinase activity has cross-reference “RHEA:23752”
obsolete all-trans undecaprenol kinase activity exactMatch 23752
obsolete all-trans undecaprenol kinase activity definition “Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+.”
- has cross-reference “RHEA:23752”
obsolete all-trans undecaprenol kinase activity label “all-trans undecaprenol kinase activity”
obsolete all-trans undecaprenol kinase activity SubClassOf undecaprenol kinase activity
obsolete all-trans undecaprenol kinase activity SubClassOf has participant some hydron
obsolete all-trans undecaprenol kinase activity SubClassOf has participant some all-trans-undecaprenol
obsolete all-trans undecaprenol kinase activity SubClassOf has participant some ATP(4-)
obsolete all-trans undecaprenol kinase activity SubClassOf has participant some ADP(3-)
obsolete all-trans undecaprenol kinase activity SubClassOf has participant some undecaprenyl phosphate(2-)

Added

obsolete all-trans undecaprenol kinase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32370”^^anyURI
obsolete all-trans undecaprenol kinase activity term replaced by undecaprenol kinase activity
obsolete all-trans undecaprenol kinase activity definition “OBSOLETE. Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+.”
- has cross-reference “RHEA:23752”
obsolete all-trans undecaprenol kinase activity deprecated true
obsolete all-trans undecaprenol kinase activity comment “This term was obsoleted because undecaprenol kinase (UdpK) has broad substrate specificity and phosphorylates both all-trans- and di-trans,poly-cis-undecaprenol (PMID:33310291), so a single grouping term (GO:0009038, undecaprenol kinase activity) is sufficient rather than splitting by isomer.”
obsolete all-trans undecaprenol kinase activity label “obsolete all-trans undecaprenol kinase activity”

obsolete amino acid activation `http://purl.obolibrary.org/obo/GO_0043038`

Removed

obsolete amino acid activation definition “The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule.”
- has cross-reference “GOC:jl”
obsolete amino acid activation label “amino acid activation”
obsolete amino acid activation SubClassOf amino acid metabolic process

Added

obsolete amino acid activation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete amino acid activation consider tRNA charging
obsolete amino acid activation consider amino acid–[peptidyl-carrier protein] ligase activity
obsolete amino acid activation definition “OBSOLETE. The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule.”
- has cross-reference “GOC:jl”
obsolete amino acid activation deprecated true
obsolete amino acid activation comment “The reason for obsoletion is that this term grouped two processes that do not share a common biology: tRNA aminoacylation (GO:0043039), in which the amino acid is esterified to a tRNA and is not itself metabolized, and nonribosomal amino acid activation (GO:0043041), in which the amino acid is covalently modified (adenylylated). Its placement under ‘amino acid metabolic process’ therefore caused tRNA aminoacylation and all of its descendants to be inferred as amino acid metabolism, which the GO editors rejected. Because no residual process is common to both children, the grouping term has been obsoleted rather than redefined. Consider GO:0043039 for tRNA charging and GO:7770118 for nonribosomal activation.”
obsolete amino acid activation label “obsolete amino acid activation”

obsolete amino acid activation for nonribosomal peptide biosynthetic process `http://purl.obolibrary.org/obo/GO_0043041`

Removed

obsolete amino acid activation for nonribosomal peptide biosynthetic process definition “Activation of an amino acid for incorporation into a peptide by a nonribosomal process.”
- has cross-reference “GOC:jl”
obsolete amino acid activation for nonribosomal peptide biosynthetic process label “amino acid activation for nonribosomal peptide biosynthetic process”
obsolete amino acid activation for nonribosomal peptide biosynthetic process SubClassOf obsolete amino acid activation
obsolete amino acid activation for nonribosomal peptide biosynthetic process SubClassOf part of some nonribosomal peptide biosynthetic process

Added

obsolete amino acid activation for nonribosomal peptide biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete amino acid activation for nonribosomal peptide biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/30872”^^anyURI
obsolete amino acid activation for nonribosomal peptide biosynthetic process consider amino acid–[peptidyl-carrier protein] ligase activity
obsolete amino acid activation for nonribosomal peptide biosynthetic process definition “OBSOLETE. Activation of an amino acid for incorporation into a peptide by a nonribosomal process.”
- has cross-reference “GOC:jl”
obsolete amino acid activation for nonribosomal peptide biosynthetic process deprecated true
obsolete amino acid activation for nonribosomal peptide biosynthetic process comment “The reason for obsoletion is that this term restates a single molecular function. Activation of an amino acid for nonribosomal incorporation is one catalysed reaction, adenylation of the amino acid followed by its transfer as a thioester onto the phosphopantetheine group of a carrier protein, and is fully covered by GO:7770118. Consider GO:7770118.”
obsolete amino acid activation for nonribosomal peptide biosynthetic process label “obsolete amino acid activation for nonribosomal peptide biosynthetic process”

obsolete amino acid adenylylation by nonribosomal peptide synthase `http://purl.obolibrary.org/obo/GO_0043042`

Removed

obsolete amino acid adenylylation by nonribosomal peptide synthase definition “Activation of an amino acid for incorporation into a peptide by a nonribosomal process, catalyzed by subunits of nonribosomal peptide synthase. The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor.”
- has cross-reference “PMID:9250661”
- has cross-reference “PMID:9712910”
- has cross-reference “GOC:jl”
obsolete amino acid adenylylation by nonribosomal peptide synthase label “amino acid adenylylation by nonribosomal peptide synthase”
obsolete amino acid adenylylation by nonribosomal peptide synthase SubClassOf obsolete amino acid activation for nonribosomal peptide biosynthetic process

Added

obsolete amino acid adenylylation by nonribosomal peptide synthase term tracker item “https://github.com/geneontology/go-ontology/issues/30872”^^anyURI
obsolete amino acid adenylylation by nonribosomal peptide synthase consider amino acid–[peptidyl-carrier protein] ligase activity
obsolete amino acid adenylylation by nonribosomal peptide synthase definition “OBSOLETE. Activation of an amino acid for incorporation into a peptide by a nonribosomal process, catalyzed by subunits of nonribosomal peptide synthase. The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor.”
- has cross-reference “PMID:9250661”
- has cross-reference “PMID:9712910”
- has cross-reference “GOC:jl”
obsolete amino acid adenylylation by nonribosomal peptide synthase deprecated true
obsolete amino acid adenylylation by nonribosomal peptide synthase comment “The reason for obsoletion is that this term restates a single molecular function, and names the same reaction as its former parent GO:0043041 with the gene product carrying it out. The reaction is fully covered by GO:7770118. Consider GO:7770118.”
obsolete amino acid adenylylation by nonribosomal peptide synthase label “obsolete amino acid adenylylation by nonribosomal peptide synthase”

obsolete arachidonate omega-hydroxylase activity `http://purl.obolibrary.org/obo/GO_0052869`

Removed

obsolete arachidonate omega-hydroxylase activity has cross-reference “KEGG_REACTION:R07041”
obsolete arachidonate omega-hydroxylase activity has cross-reference “MetaCyc:RXN-19677”
obsolete arachidonate omega-hydroxylase activity has cross-reference “RHEA:39755”
obsolete arachidonate omega-hydroxylase activity exactMatch 39755
obsolete arachidonate omega-hydroxylase activity definition “Catalysis of the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH–hemoprotein reductase] = 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H+ + H2O + oxidized [NADPH–hemoprotein reductase]. (5Z,8Z,11Z,14Z)-icosatetraenoic acid is also known as arachidonic acid is also and 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate as 20-HETE.”
- has cross-reference “RHEA:39755”
obsolete arachidonate omega-hydroxylase activity has exact synonym “arachidonic acid:oxygen 1-oxidoreductase activity”
- has_synonym_type Systematic synonym
obsolete arachidonate omega-hydroxylase activity label “arachidonate omega-hydroxylase activity”
obsolete arachidonate omega-hydroxylase activity SubClassOf oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
obsolete arachidonate omega-hydroxylase activity SubClassOf has participant some water
obsolete arachidonate omega-hydroxylase activity SubClassOf has participant some hydron
obsolete arachidonate omega-hydroxylase activity SubClassOf has participant some dioxygen
obsolete arachidonate omega-hydroxylase activity SubClassOf has participant some arachidonate
obsolete arachidonate omega-hydroxylase activity SubClassOf has participant some FMNH2(2-)
obsolete arachidonate omega-hydroxylase activity SubClassOf has participant some FMN(3-)
obsolete arachidonate omega-hydroxylase activity SubClassOf has participant some 20-HETE(1-)

Added

obsolete arachidonate omega-hydroxylase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32501”^^anyURI
obsolete arachidonate omega-hydroxylase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32503”^^anyURI
obsolete arachidonate omega-hydroxylase activity term replaced by long-chain fatty acid omega-hydroxylase activity
obsolete arachidonate omega-hydroxylase activity has exact synonym “arachidonic acid:oxygen 1-oxidoreductase activity”
obsolete arachidonate omega-hydroxylase activity definition “OBSOLETE. Catalysis of the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH–hemoprotein reductase] = 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H+ + H2O + oxidized [NADPH–hemoprotein reductase]. (5Z,8Z,11Z,14Z)-icosatetraenoic acid is also known as arachidonic acid is also and 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate as 20-HETE.”
- has cross-reference “RHEA:39755”
obsolete arachidonate omega-hydroxylase activity deprecated true
obsolete arachidonate omega-hydroxylase activity comment “The reason for obsoletion is that this term represents a specific substrate of the parent term.”
obsolete arachidonate omega-hydroxylase activity label “obsolete arachidonate omega-hydroxylase activity”

obsolete arginyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006420`

Removed

obsolete arginyl-tRNA aminoacylation definition “The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of an alanine accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete arginyl-tRNA aminoacylation label “arginyl-tRNA aminoacylation”
obsolete arginyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete arginyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete arginyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete arginyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete arginyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of an alanine accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete arginyl-tRNA aminoacylation deprecated true
obsolete arginyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004814 arginine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete arginyl-tRNA aminoacylation label “obsolete arginyl-tRNA aminoacylation”

obsolete aryl hydrocarbon receptor binding `http://purl.obolibrary.org/obo/GO_0017162`

Removed

obsolete aryl hydrocarbon receptor binding conformsTo binding.yaml
obsolete aryl hydrocarbon receptor binding definition “Binding to an aryl hydrocarbon receptor.”
- has cross-reference “GOC:ai”
obsolete aryl hydrocarbon receptor binding label “aryl hydrocarbon receptor binding”
obsolete aryl hydrocarbon receptor binding EquivalentTo binding and (has primary input some aryl hydrocarbon receptor)
obsolete aryl hydrocarbon receptor binding SubClassOf signaling receptor binding
obsolete aryl hydrocarbon receptor binding SubClassOf RNA polymerase II-specific DNA-binding transcription factor binding
obsolete aryl hydrocarbon receptor binding SubClassOf has primary input some aryl hydrocarbon receptor

Added

obsolete aryl hydrocarbon receptor binding term tracker item “https://github.com/geneontology/go-ontology/issues/32477”^^anyURI
obsolete aryl hydrocarbon receptor binding consider RNA polymerase II-specific DNA-binding transcription factor binding
obsolete aryl hydrocarbon receptor binding definition “OBSOLETE. Binding to an aryl hydrocarbon receptor.”
- has cross-reference “GOC:ai”
obsolete aryl hydrocarbon receptor binding deprecated true
obsolete aryl hydrocarbon receptor binding comment “The reason for obsoletion is that this term represents a gene product. Better captured with GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding, with aryl hydrocarbon receptor as ‘has_input’ in annotation extension.”
obsolete aryl hydrocarbon receptor binding label “obsolete aryl hydrocarbon receptor binding”

obsolete asparaginyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006421`

Removed

obsolete asparaginyl-tRNA aminoacylation definition “The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of an asparagine-accetping tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete asparaginyl-tRNA aminoacylation label “asparaginyl-tRNA aminoacylation”
obsolete asparaginyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete asparaginyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete asparaginyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete asparaginyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete asparaginyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of an asparagine-accetping tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete asparaginyl-tRNA aminoacylation deprecated true
obsolete asparaginyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004816 asparagine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete asparaginyl-tRNA aminoacylation label “obsolete asparaginyl-tRNA aminoacylation”

obsolete aspartyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006422`

Removed

obsolete aspartyl-tRNA aminoacylation definition “The process of coupling aspartate to aspartyl-tRNA, catalyzed by aspartyl-tRNA synthetase. The aspartyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of an aspartic acid accetping tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “ISBN:0716730510”
obsolete aspartyl-tRNA aminoacylation label “aspartyl-tRNA aminoacylation”
obsolete aspartyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete aspartyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete aspartyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete aspartyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete aspartyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling aspartate to aspartyl-tRNA, catalyzed by aspartyl-tRNA synthetase. The aspartyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of an aspartic acid accetping tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “ISBN:0716730510”
obsolete aspartyl-tRNA aminoacylation deprecated true
obsolete aspartyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004815 aspartate-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete aspartyl-tRNA aminoacylation label “obsolete aspartyl-tRNA aminoacylation”

obsolete benzonitrile metabolic process `http://purl.obolibrary.org/obo/GO_0018876`

Removed

obsolete benzonitrile metabolic process conformsTo metabolic_process.yaml

obsolete beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process `http://purl.obolibrary.org/obo/GO_0018877`

Removed

obsolete beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process conformsTo metabolic_process.yaml

obsolete bromoxynil metabolic process `http://purl.obolibrary.org/obo/GO_0018881`

Removed

obsolete bromoxynil metabolic process conformsTo metabolic_process.yaml

obsolete canonical glycolysis `http://purl.obolibrary.org/obo/GO_0061621`

Removed

obsolete canonical glycolysis has cross-reference “MetaCyc:ANAGLYCOLYSIS-PWY”
obsolete canonical glycolysis has cross-reference “Wikipedia:Glycolysis”
obsolete canonical glycolysis definition “The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
obsolete canonical glycolysis label “canonical glycolysis”
obsolete canonical glycolysis EquivalentTo obsolete glycolytic process through glucose-6-phosphate and (has part some glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity) and (starts with some glucokinase activity) and (has primary output some NADH(2-)) and (has primary input some D-glucopyranose)
obsolete canonical glycolysis SubClassOf glucose catabolic process
obsolete canonical glycolysis SubClassOf obsolete glycolytic process through glucose-6-phosphate
obsolete canonical glycolysis SubClassOf has part some glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
obsolete canonical glycolysis SubClassOf starts with some glucokinase activity
obsolete canonical glycolysis SubClassOf has primary output some NADH(2-)

Added

obsolete canonical glycolysis term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete canonical glycolysis term replaced by glycolysis
obsolete canonical glycolysis definition “OBSOLETE. The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
obsolete canonical glycolysis deprecated true
obsolete canonical glycolysis comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete canonical glycolysis label “obsolete canonical glycolysis”

obsolete carbon catabolite activation of transcription from RNA polymerase II promoter `http://purl.obolibrary.org/obo/GO_0000436`

Removed

obsolete carbon catabolite activation of transcription from RNA polymerase II promoter definition “Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.”
- has cross-reference “GOC:krc”
obsolete carbon catabolite activation of transcription from RNA polymerase II promoter label “carbon catabolite activation of transcription from RNA polymerase II promoter”
obsolete carbon catabolite activation of transcription from RNA polymerase II promoter SubClassOf obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter
obsolete carbon catabolite activation of transcription from RNA polymerase II promoter SubClassOf positive regulation of transcription by RNA polymerase II
obsolete carbon catabolite activation of transcription from RNA polymerase II promoter SubClassOf carbon catabolite activation of transcription

Added

obsolete carbon catabolite activation of transcription from RNA polymerase II promoter term tracker item “https://github.com/geneontology/go-ontology/issues/21442”^^anyURI
obsolete carbon catabolite activation of transcription from RNA polymerase II promoter consider positive regulation of transcription by RNA polymerase II
obsolete carbon catabolite activation of transcription from RNA polymerase II promoter definition “OBSOLETE. Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.”
- has cross-reference “GOC:krc”
obsolete carbon catabolite activation of transcription from RNA polymerase II promoter deprecated true
obsolete carbon catabolite activation of transcription from RNA polymerase II promoter comment “The reason for obsoletion is that these terms represent GO-CAM models.”
obsolete carbon catabolite activation of transcription from RNA polymerase II promoter label “obsolete carbon catabolite activation of transcription from RNA polymerase II promoter”

obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter `http://purl.obolibrary.org/obo/GO_0000429`

Removed

obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter definition “A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:krc”
obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter label “carbon catabolite regulation of transcription from RNA polymerase II promoter”
obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter SubClassOf regulation of transcription by RNA polymerase II
obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter SubClassOf carbon catabolite regulation of transcription

Added

obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter term tracker item “https://github.com/geneontology/go-ontology/issues/21442”^^anyURI
obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter consider regulation of transcription by RNA polymerase II
obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter definition “OBSOLETE. A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:krc”
obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter deprecated true
obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter comment “The reason for obsoletion is that these terms represent GO-CAM models.”
obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter label “obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter”

obsolete carbon catabolite repression of transcription from RNA polymerase II promoter by galactose `http://purl.obolibrary.org/obo/GO_0000434`

Removed

obsolete carbon catabolite repression of transcription from RNA polymerase II promoter by galactose term tracker item “The reason for obsoletion is that these terms represent GO-CAM models.”^^anyURI

Added

obsolete carbon catabolite repression of transcription from RNA polymerase II promoter by galactose term tracker item “https://github.com/geneontology/go-ontology/issues/21442”^^anyURI
obsolete carbon catabolite repression of transcription from RNA polymerase II promoter by galactose consider negative regulation of transcription by RNA polymerase II

obsolete cellodextrin metabolic process `http://purl.obolibrary.org/obo/GO_2000889`

Removed

obsolete cellodextrin metabolic process conformsTo metabolic_process.yaml

obsolete cellotriose metabolic process `http://purl.obolibrary.org/obo/GO_2000893`

Removed

obsolete cellotriose metabolic process conformsTo metabolic_process.yaml

obsolete cephalosporin C metabolic process `http://purl.obolibrary.org/obo/GO_1901266`

Removed

obsolete cephalosporin C metabolic process conformsTo metabolic_process.yaml

obsolete cordyol C biosynthetic process `http://purl.obolibrary.org/obo/GO_1900799`

Removed

obsolete cordyol C biosynthetic process conformsTo biosynthetic_process.yaml

obsolete cordyol C catabolic process `http://purl.obolibrary.org/obo/GO_1900798`

Removed

obsolete cordyol C catabolic process conformsTo catabolic_process.yaml

obsolete cordyol C metabolic process `http://purl.obolibrary.org/obo/GO_1900797`

Removed

obsolete cordyol C metabolic process conformsTo metabolic_process.yaml

obsolete cyclohexylsulfamate metabolic process `http://purl.obolibrary.org/obo/GO_0018892`

Removed

obsolete cyclohexylsulfamate metabolic process conformsTo metabolic_process.yaml

obsolete cysteinyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006423`

Removed

obsolete cysteinyl-tRNA aminoacylation definition “The process of coupling L-cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a cysteine-accepting tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete cysteinyl-tRNA aminoacylation label “cysteinyl-tRNA aminoacylation”
obsolete cysteinyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete cysteinyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete cysteinyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete cysteinyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete cysteinyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling L-cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a cysteine-accepting tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete cysteinyl-tRNA aminoacylation deprecated true
obsolete cysteinyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004817 cysteine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete cysteinyl-tRNA aminoacylation label “obsolete cysteinyl-tRNA aminoacylation”

obsolete cytoplasmic alanyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_1990762`

Removed

obsolete cytoplasmic alanyl-tRNA aminoacylation definition “The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase involved in cytoplasmic translation.”
- has cross-reference “GOC:vw”
obsolete cytoplasmic alanyl-tRNA aminoacylation label “cytoplasmic alanyl-tRNA aminoacylation”
obsolete cytoplasmic alanyl-tRNA aminoacylation SubClassOf obsolete alanyl-tRNA aminoacylation
obsolete cytoplasmic alanyl-tRNA aminoacylation SubClassOf part of some cytoplasmic translation
obsolete cytoplasmic alanyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete cytoplasmic alanyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete cytoplasmic alanyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete cytoplasmic alanyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase involved in cytoplasmic translation.”
- has cross-reference “GOC:vw”
obsolete cytoplasmic alanyl-tRNA aminoacylation deprecated true
obsolete cytoplasmic alanyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004813 alanine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete cytoplasmic alanyl-tRNA aminoacylation label “obsolete cytoplasmic alanyl-tRNA aminoacylation”

obsolete cytosolic valyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0061475`

Removed

obsolete cytosolic valyl-tRNA aminoacylation definition “The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:dph”
obsolete cytosolic valyl-tRNA aminoacylation label “cytosolic valyl-tRNA aminoacylation”
obsolete cytosolic valyl-tRNA aminoacylation EquivalentTo obsolete valyl-tRNA aminoacylation and (occurs in some cytosol)
obsolete cytosolic valyl-tRNA aminoacylation SubClassOf obsolete valyl-tRNA aminoacylation
obsolete cytosolic valyl-tRNA aminoacylation SubClassOf occurs in some cytosol
obsolete cytosolic valyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete cytosolic valyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete cytosolic valyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete cytosolic valyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:dph”
obsolete cytosolic valyl-tRNA aminoacylation deprecated true
obsolete cytosolic valyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004832 valine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete cytosolic valyl-tRNA aminoacylation label “obsolete cytosolic valyl-tRNA aminoacylation”

obsolete detection of endoplasmic reticulum overloading `http://purl.obolibrary.org/obo/GO_0002234`

Removed

obsolete detection of endoplasmic reticulum overloading definition “The series of events in which a stimulus generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum is received and converted into a molecular signal.”
- has cross-reference “PMID:10390516”
- has cross-reference “GOC:add”
obsolete detection of endoplasmic reticulum overloading label “detection of endoplasmic reticulum overloading”
obsolete detection of endoplasmic reticulum overloading SubClassOf ER overload response
obsolete detection of endoplasmic reticulum overloading SubClassOf detection of biotic stimulus

Added

obsolete detection of endoplasmic reticulum overloading term tracker item “https://github.com/geneontology/go-ontology/issues/32516”^^anyURI
obsolete detection of endoplasmic reticulum overloading definition “OBSOLETE. The series of events in which a stimulus generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum is received and converted into a molecular signal.”
- has cross-reference “PMID:10390516”
- has cross-reference “GOC:add”
obsolete detection of endoplasmic reticulum overloading deprecated true
obsolete detection of endoplasmic reticulum overloading comment “The reason for obsoletion is that the term was made in error and describes a molecular function.”
obsolete detection of endoplasmic reticulum overloading label “obsolete detection of endoplasmic reticulum overloading”

obsolete di-trans, poly-cis-undecaprenol kinase activity `http://purl.obolibrary.org/obo/GO_0036433`

Removed

obsolete di-trans, poly-cis-undecaprenol kinase activity has cross-reference “EC:2.7.1.66”
obsolete di-trans, poly-cis-undecaprenol kinase activity has cross-reference “KEGG_REACTION:R05626”
obsolete di-trans, poly-cis-undecaprenol kinase activity has cross-reference “MetaCyc:UNDECAPRENOL-KINASE-RXN”
obsolete di-trans, poly-cis-undecaprenol kinase activity has cross-reference “RHEA:28122”
obsolete di-trans, poly-cis-undecaprenol kinase activity has_related_synonym “ditrans,polycis-undecaprenol kinase activity”
obsolete di-trans, poly-cis-undecaprenol kinase activity exactMatch UNDECAPRENOL-KINASE-RXN
obsolete di-trans, poly-cis-undecaprenol kinase activity exactMatch 2.7.1.66
obsolete di-trans, poly-cis-undecaprenol kinase activity exactMatch 28122
obsolete di-trans, poly-cis-undecaprenol kinase activity exactMatch R05626
obsolete di-trans, poly-cis-undecaprenol kinase activity definition “Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+.”
- has cross-reference “RHEA:28122”
obsolete di-trans, poly-cis-undecaprenol kinase activity label “di-trans, poly-cis-undecaprenol kinase activity”
obsolete di-trans, poly-cis-undecaprenol kinase activity SubClassOf undecaprenol kinase activity
obsolete di-trans, poly-cis-undecaprenol kinase activity SubClassOf has participant some hydron
obsolete di-trans, poly-cis-undecaprenol kinase activity SubClassOf has participant some ATP(4-)
obsolete di-trans, poly-cis-undecaprenol kinase activity SubClassOf has participant some ADP(3-)
obsolete di-trans, poly-cis-undecaprenol kinase activity SubClassOf has participant some ditrans,polycis-undecaprenyl phosphate(2-)
obsolete di-trans, poly-cis-undecaprenol kinase activity SubClassOf has participant some ditrans,polycis-undecaprenol

Added

obsolete di-trans, poly-cis-undecaprenol kinase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32370”^^anyURI
obsolete di-trans, poly-cis-undecaprenol kinase activity term replaced by undecaprenol kinase activity
obsolete di-trans, poly-cis-undecaprenol kinase activity definition “OBSOLETE. Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+.”
- has cross-reference “RHEA:28122”
obsolete di-trans, poly-cis-undecaprenol kinase activity deprecated true
obsolete di-trans, poly-cis-undecaprenol kinase activity comment “This term was obsoleted because undecaprenol kinase (UdpK) has broad substrate specificity and phosphorylates both all-trans- and di-trans,poly-cis-undecaprenol (PMID:33310291), so a single grouping term (GO:0009038, undecaprenol kinase activity) is sufficient rather than splitting by isomer.”
obsolete di-trans, poly-cis-undecaprenol kinase activity label “obsolete di-trans, poly-cis-undecaprenol kinase activity”

obsolete diaminopimelate biosynthetic process `http://purl.obolibrary.org/obo/GO_0019877`

Removed

obsolete diaminopimelate biosynthetic process consider L-leucine biosynthetic process
obsolete diaminopimelate biosynthetic process comment “This term was obsoleted because it represents an intermediate in L-leucine biosynthesis.”

Added

obsolete diaminopimelate biosynthetic process consider L-lysine biosynthetic process
obsolete diaminopimelate biosynthetic process comment “This term was obsoleted because it represents an intermediate in L-lysine biosynthesis.”

obsolete dimethyl ether metabolic process `http://purl.obolibrary.org/obo/GO_0018905`

Removed

obsolete dimethyl ether metabolic process conformsTo metabolic_process.yaml

obsolete dimethylsilanediol metabolic process `http://purl.obolibrary.org/obo/GO_0046454`

Removed

obsolete dimethylsilanediol metabolic process conformsTo metabolic_process.yaml

obsolete diorcinol biosynthetic process `http://purl.obolibrary.org/obo/GO_1900572`

Removed

obsolete diorcinol biosynthetic process conformsTo biosynthetic_process.yaml

obsolete diorcinol catabolic process `http://purl.obolibrary.org/obo/GO_1900571`

Removed

obsolete diorcinol catabolic process conformsTo catabolic_process.yaml

obsolete diorcinol metabolic process `http://purl.obolibrary.org/obo/GO_1900570`

Removed

obsolete diorcinol metabolic process conformsTo metabolic_process.yaml

obsolete ent-kaurene metabolic process `http://purl.obolibrary.org/obo/GO_0033331`

Removed

obsolete ent-kaurene metabolic process conformsTo metabolic_process.yaml
obsolete ent-kaurene metabolic process definition “The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.”
- has cross-reference “GOC:mah”
- has cross-reference “PMID:17064690”
obsolete ent-kaurene metabolic process label “ent-kaurene metabolic process”
obsolete ent-kaurene metabolic process EquivalentTo metabolic process and (has primary input or output some ent-kaurene)
obsolete ent-kaurene metabolic process SubClassOf terpene metabolic process
obsolete ent-kaurene metabolic process SubClassOf has primary input or output some ent-kaurene

Added

obsolete ent-kaurene metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/28120”^^anyURI
obsolete ent-kaurene metabolic process consider ent-kaurene biosynthetic process
obsolete ent-kaurene metabolic process definition “OBSOLETE. The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.”
- has cross-reference “GOC:mah”
- has cross-reference “PMID:17064690”
obsolete ent-kaurene metabolic process deprecated true
obsolete ent-kaurene metabolic process comment “The reason for obsoletion is that this term was an unnecessary grouping term.”
obsolete ent-kaurene metabolic process label “obsolete ent-kaurene metabolic process”

obsolete envenomation resulting in occlusion of the pore of voltage-gated potassium channel `http://purl.obolibrary.org/obo/GO_0044564`

Removed

obsolete envenomation resulting in occlusion of the pore of voltage-gated potassium channel term replaced by obsolete venom-mediated inhibition of voltage-gated potassium channel activity

obsolete envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel `http://purl.obolibrary.org/obo/GO_0044563`

Removed

obsolete envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel term replaced by obsolete venom-mediated inhibition of voltage-gated potassium channel activity

obsolete establishment of central gap gene boundaries `http://purl.obolibrary.org/obo/GO_0007358`

Removed

obsolete establishment of central gap gene boundaries definition “OBSOLETE. Specification of the borders of central gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by knirps repression of Kruppel.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

obsolete establishment of central gap gene boundaries term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
obsolete establishment of central gap gene boundaries definition “OBSOLETE. Specification of the borders of central gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by knirps repression of Kruppel.”
- has cross-reference “ISBN:0879694238”

obsolete establishment of posterior gap gene boundaries `http://purl.obolibrary.org/obo/GO_0007361`

Removed

obsolete establishment of posterior gap gene boundaries definition “OBSOLETE. Specification of the borders of posterior gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by hunchback and tailless repression of knirps.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

obsolete establishment of posterior gap gene boundaries definition “OBSOLETE. Specification of the borders of posterior gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by hunchback and tailless repression of knirps.”
- has cross-reference “ISBN:0879694238”

obsolete establishment of terminal gap gene boundary `http://purl.obolibrary.org/obo/GO_0007364`

Removed

obsolete establishment of terminal gap gene boundary definition “OBSOLETE. Specification of the borders of terminal gap gene expression mediated largely by the effects of other gap genes.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

obsolete establishment of terminal gap gene boundary definition “OBSOLETE. Specification of the borders of terminal gap gene expression mediated largely by the effects of other gap genes.”
- has cross-reference “ISBN:0879694238”

obsolete establishment or maintenance of bipolar cell polarity regulating cell shape `http://purl.obolibrary.org/obo/GO_0061246`

Removed

obsolete establishment or maintenance of bipolar cell polarity regulating cell shape definition “Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.”
- has cross-reference “GOC:dph”
- has cross-reference “GOC:vw”
obsolete establishment or maintenance of bipolar cell polarity regulating cell shape label “establishment or maintenance of bipolar cell polarity regulating cell shape”
obsolete establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf establishment or maintenance of bipolar cell polarity
obsolete establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf establishment or maintenance of cell polarity regulating cell shape
obsolete establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

Added

obsolete establishment or maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI
obsolete establishment or maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity
obsolete establishment or maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.”
- has cross-reference “GOC:dph”
- has cross-reference “GOC:vw”
obsolete establishment or maintenance of bipolar cell polarity regulating cell shape deprecated true
obsolete establishment or maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”
obsolete establishment or maintenance of bipolar cell polarity regulating cell shape label “obsolete establishment or maintenance of bipolar cell polarity regulating cell shape”

obsolete fructosamine metabolic process `http://purl.obolibrary.org/obo/GO_0030389`

Removed

obsolete fructosamine metabolic process conformsTo metabolic_process.yaml
obsolete fructosamine metabolic process definition “The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.”
- has cross-reference “ISBN:0192801023”
- has cross-reference “GOC:jl”
obsolete fructosamine metabolic process label “fructosamine metabolic process”
obsolete fructosamine metabolic process EquivalentTo metabolic process and (has primary input or output some fructosamine)
obsolete fructosamine metabolic process SubClassOf amino sugar metabolic process
obsolete fructosamine metabolic process SubClassOf has primary input or output some fructosamine

Added

obsolete fructosamine metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32273”^^anyURI
obsolete fructosamine metabolic process consider fructosamine biosynthetic process
obsolete fructosamine metabolic process consider fructosamine catabolic process
obsolete fructosamine metabolic process definition “OBSOLETE. The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.”
- has cross-reference “ISBN:0192801023”
- has cross-reference “GOC:jl”
obsolete fructosamine metabolic process deprecated true
obsolete fructosamine metabolic process comment “The reason for obsoletion is that this term was made in error and is an unnecessary grouping term.”
obsolete fructosamine metabolic process label “obsolete fructosamine metabolic process”

obsolete gentamycin catabolic process `http://purl.obolibrary.org/obo/GO_1901129`

Removed

obsolete gentamycin catabolic process conformsTo catabolic_process.yaml

obsolete gentamycin metabolic process `http://purl.obolibrary.org/obo/GO_1901128`

Removed

obsolete gentamycin metabolic process conformsTo metabolic_process.yaml

obsolete glutaminyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006425`

Removed

obsolete glutaminyl-tRNA aminoacylation definition “The process of coupling glutamine to glutaminyl-tRNA, catalyzed by glutaminyl-tRNA synthetase. The glutaminyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a glutamine-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete glutaminyl-tRNA aminoacylation label “glutaminyl-tRNA aminoacylation”
obsolete glutaminyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete glutaminyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete glutaminyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete glutaminyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete glutaminyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling glutamine to glutaminyl-tRNA, catalyzed by glutaminyl-tRNA synthetase. The glutaminyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a glutamine-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete glutaminyl-tRNA aminoacylation deprecated true
obsolete glutaminyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004819 glutamine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete glutaminyl-tRNA aminoacylation label “obsolete glutaminyl-tRNA aminoacylation”

obsolete glutaminyl-tRNAGln biosynthesis via transamidation `http://purl.obolibrary.org/obo/GO_0070681`

Removed

obsolete glutaminyl-tRNAGln biosynthesis via transamidation has cross-reference “MetaCyc:PWY-5921”
obsolete glutaminyl-tRNAGln biosynthesis via transamidation definition “A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase.”
- has cross-reference “GOC:mah”
- has cross-reference “MetaCyc:PWY-5921”
obsolete glutaminyl-tRNAGln biosynthesis via transamidation label “glutaminyl-tRNAGln biosynthesis via transamidation”
obsolete glutaminyl-tRNAGln biosynthesis via transamidation SubClassOf tRNA charging

Added

obsolete glutaminyl-tRNAGln biosynthesis via transamidation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete glutaminyl-tRNAGln biosynthesis via transamidation consider tRNA charging
obsolete glutaminyl-tRNAGln biosynthesis via transamidation consider glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
obsolete glutaminyl-tRNAGln biosynthesis via transamidation definition “OBSOLETE. A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase.”
- has cross-reference “GOC:mah”
- has cross-reference “MetaCyc:PWY-5921”
obsolete glutaminyl-tRNAGln biosynthesis via transamidation deprecated true
obsolete glutaminyl-tRNAGln biosynthesis via transamidation comment “The reason for obsoletion is that this term represents a specific pathway variant, which is out of scope for GO, following the obsoletion of its structural twin GO:0070680 asparaginyl-tRNAAsn biosynthesis via transamidation. No replaced_by is given because no single term is a safe automatic substitution: the amidotransferase step is GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity, while GatCAB subunits act on an already-charged tRNA and may belong under GO:0019988 charged-tRNA amino acid modification rather than under tRNA charging at all. Annotations require review rather than migration.”
obsolete glutaminyl-tRNAGln biosynthesis via transamidation label “obsolete glutaminyl-tRNAGln biosynthesis via transamidation”

obsolete glutamyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006424`

Removed

obsolete glutamyl-tRNA aminoacylation definition “The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a glutamic acid-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete glutamyl-tRNA aminoacylation label “glutamyl-tRNA aminoacylation”
obsolete glutamyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete glutamyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete glutamyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete glutamyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete glutamyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a glutamic acid-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete glutamyl-tRNA aminoacylation deprecated true
obsolete glutamyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004818 glutamate-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete glutamyl-tRNA aminoacylation label “obsolete glutamyl-tRNA aminoacylation”

obsolete glycolysis from storage polysaccharide through glucose-1-phosphate `http://purl.obolibrary.org/obo/GO_0093001`

Removed

obsolete glycolysis from storage polysaccharide through glucose-1-phosphate definition “The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH.”
- has cross-reference “GOC:glycolysis”
- has cross-reference “GOC:dph”
obsolete glycolysis from storage polysaccharide through glucose-1-phosphate label “glycolysis from storage polysaccharide through glucose-1-phosphate”
obsolete glycolysis from storage polysaccharide through glucose-1-phosphate EquivalentTo obsolete glycolytic process through glucose-1-phosphate and (has primary input some polysaccharide)
obsolete glycolysis from storage polysaccharide through glucose-1-phosphate SubClassOf polysaccharide catabolic process
obsolete glycolysis from storage polysaccharide through glucose-1-phosphate SubClassOf obsolete glycolytic process through glucose-1-phosphate

Added

obsolete glycolysis from storage polysaccharide through glucose-1-phosphate term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete glycolysis from storage polysaccharide through glucose-1-phosphate term replaced by glycolysis
obsolete glycolysis from storage polysaccharide through glucose-1-phosphate definition “OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH.”
- has cross-reference “GOC:glycolysis”
- has cross-reference “GOC:dph”
obsolete glycolysis from storage polysaccharide through glucose-1-phosphate deprecated true
obsolete glycolysis from storage polysaccharide through glucose-1-phosphate comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete glycolysis from storage polysaccharide through glucose-1-phosphate label “obsolete glycolysis from storage polysaccharide through glucose-1-phosphate”

obsolete glycolytic process from fructose through fructose-6-phosphate `http://purl.obolibrary.org/obo/GO_0061616`

Removed

obsolete glycolytic process from fructose through fructose-6-phosphate definition “The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
obsolete glycolytic process from fructose through fructose-6-phosphate label “glycolytic process from fructose through fructose-6-phosphate”
obsolete glycolytic process from fructose through fructose-6-phosphate EquivalentTo obsolete glycolytic process through fructose-6-phosphate and (starts with some fructokinase activity) and (has primary input some fructose)
obsolete glycolytic process from fructose through fructose-6-phosphate SubClassOf fructose catabolic process
obsolete glycolytic process from fructose through fructose-6-phosphate SubClassOf obsolete glycolytic process through fructose-6-phosphate
obsolete glycolytic process from fructose through fructose-6-phosphate SubClassOf starts with some fructokinase activity

Added

obsolete glycolytic process from fructose through fructose-6-phosphate term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete glycolytic process from fructose through fructose-6-phosphate term replaced by glycolysis
obsolete glycolytic process from fructose through fructose-6-phosphate definition “OBSOLETE. The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
obsolete glycolytic process from fructose through fructose-6-phosphate deprecated true
obsolete glycolytic process from fructose through fructose-6-phosphate comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete glycolytic process from fructose through fructose-6-phosphate label “obsolete glycolytic process from fructose through fructose-6-phosphate”

obsolete glycolytic process from galactose `http://purl.obolibrary.org/obo/GO_0061623`

Removed

obsolete glycolytic process from galactose definition “The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
obsolete glycolytic process from galactose label “glycolytic process from galactose”
obsolete glycolytic process from galactose EquivalentTo obsolete glycolytic process through glucose-1-phosphate and (starts with some beta-D-galactose catabolic process via UDP-galactose, Leloir pathway) and (has primary input some galactose)
obsolete glycolytic process from galactose SubClassOf galactose catabolic process
obsolete glycolytic process from galactose SubClassOf obsolete glycolytic process through glucose-1-phosphate
obsolete glycolytic process from galactose SubClassOf starts with some beta-D-galactose catabolic process via UDP-galactose, Leloir pathway

Added

obsolete glycolytic process from galactose term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete glycolytic process from galactose term replaced by glycolysis
obsolete glycolytic process from galactose definition “OBSOLETE. The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
obsolete glycolytic process from galactose deprecated true
obsolete glycolytic process from galactose comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete glycolytic process from galactose label “obsolete glycolytic process from galactose”

obsolete glycolytic process from mannose through fructose-6-phosphate `http://purl.obolibrary.org/obo/GO_0061619`

Removed

obsolete glycolytic process from mannose through fructose-6-phosphate definition “The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
obsolete glycolytic process from mannose through fructose-6-phosphate label “glycolytic process from mannose through fructose-6-phosphate”
obsolete glycolytic process from mannose through fructose-6-phosphate EquivalentTo obsolete glycolytic process through fructose-6-phosphate and (starts with some mannose to fructose-6-phosphate catabolic process) and (has primary input some mannose)
obsolete glycolytic process from mannose through fructose-6-phosphate SubClassOf mannose catabolic process
obsolete glycolytic process from mannose through fructose-6-phosphate SubClassOf obsolete glycolytic process through fructose-6-phosphate
obsolete glycolytic process from mannose through fructose-6-phosphate SubClassOf starts with some mannose to fructose-6-phosphate catabolic process

Added

obsolete glycolytic process from mannose through fructose-6-phosphate term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete glycolytic process from mannose through fructose-6-phosphate term replaced by glycolysis
obsolete glycolytic process from mannose through fructose-6-phosphate definition “OBSOLETE. The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
obsolete glycolytic process from mannose through fructose-6-phosphate deprecated true
obsolete glycolytic process from mannose through fructose-6-phosphate comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete glycolytic process from mannose through fructose-6-phosphate label “obsolete glycolytic process from mannose through fructose-6-phosphate”

obsolete glycolytic process from sucrose `http://purl.obolibrary.org/obo/GO_0061704`

Removed

obsolete glycolytic process from sucrose definition “The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.”
- has cross-reference “GOC:glycolysis”
- has cross-reference “GOC:dph”
- has cross-reference “PMID:15012287”
obsolete glycolytic process from sucrose label “glycolytic process from sucrose”
obsolete glycolytic process from sucrose EquivalentTo glycolysis and (has primary input some sucrose)
obsolete glycolytic process from sucrose SubClassOf sucrose catabolic process
obsolete glycolytic process from sucrose SubClassOf glycolysis

Added

obsolete glycolytic process from sucrose term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete glycolytic process from sucrose term replaced by glycolysis
obsolete glycolytic process from sucrose definition “OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.”
- has cross-reference “GOC:glycolysis”
- has cross-reference “GOC:dph”
- has cross-reference “PMID:15012287”
obsolete glycolytic process from sucrose deprecated true
obsolete glycolytic process from sucrose comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete glycolytic process from sucrose label “obsolete glycolytic process from sucrose”

obsolete glycolytic process from sucrose through glucose and fructose `http://purl.obolibrary.org/obo/GO_0061706`

Removed

obsolete glycolytic process from sucrose through glucose and fructose has cross-reference “MetaCyc:PWY-1042”
obsolete glycolytic process from sucrose through glucose and fructose definition “The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.”
- has cross-reference “GOC:glycolysis”
- has cross-reference “GOC:dph”
- has cross-reference “PMID:15012287”
- has cross-reference “MetaCyc:PWY-1042”
obsolete glycolytic process from sucrose through glucose and fructose label “glycolytic process from sucrose through glucose and fructose”
obsolete glycolytic process from sucrose through glucose and fructose SubClassOf obsolete glycolytic process from sucrose

Added

obsolete glycolytic process from sucrose through glucose and fructose term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete glycolytic process from sucrose through glucose and fructose term replaced by glycolysis
obsolete glycolytic process from sucrose through glucose and fructose definition “OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.”
- has cross-reference “GOC:glycolysis”
- has cross-reference “GOC:dph”
- has cross-reference “PMID:15012287”
- has cross-reference “MetaCyc:PWY-1042”
obsolete glycolytic process from sucrose through glucose and fructose deprecated true
obsolete glycolytic process from sucrose through glucose and fructose comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete glycolytic process from sucrose through glucose and fructose label “obsolete glycolytic process from sucrose through glucose and fructose”

obsolete glycolytic process through fructose-1-phosphate `http://purl.obolibrary.org/obo/GO_0061625`

Removed

obsolete glycolytic process through fructose-1-phosphate has cross-reference “MetaCyc:PWY-8404”
obsolete glycolytic process through fructose-1-phosphate definition “The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
obsolete glycolytic process through fructose-1-phosphate label “glycolytic process through fructose-1-phosphate”
obsolete glycolytic process through fructose-1-phosphate SubClassOf glycolysis

Added

obsolete glycolytic process through fructose-1-phosphate term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete glycolytic process through fructose-1-phosphate term replaced by glycolysis
obsolete glycolytic process through fructose-1-phosphate definition “OBSOLETE. The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
obsolete glycolytic process through fructose-1-phosphate deprecated true
obsolete glycolytic process through fructose-1-phosphate comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete glycolytic process through fructose-1-phosphate label “obsolete glycolytic process through fructose-1-phosphate”

obsolete glycolytic process through fructose-6-phosphate `http://purl.obolibrary.org/obo/GO_0061615`

Removed

obsolete glycolytic process through fructose-6-phosphate has cross-reference “MetaCyc:PWY-5484”
obsolete glycolytic process through fructose-6-phosphate definition “The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
obsolete glycolytic process through fructose-6-phosphate label “glycolytic process through fructose-6-phosphate”
obsolete glycolytic process through fructose-6-phosphate EquivalentTo glycolysis and (has part some 6-phosphofructokinase activity) and (has part some fructose-bisphosphate aldolase activity) and (has part some triose-phosphate isomerase activity)
obsolete glycolytic process through fructose-6-phosphate SubClassOf glycolysis
obsolete glycolytic process through fructose-6-phosphate SubClassOf has part some 6-phosphofructokinase activity
obsolete glycolytic process through fructose-6-phosphate SubClassOf has part some fructose-bisphosphate aldolase activity
obsolete glycolytic process through fructose-6-phosphate SubClassOf has part some triose-phosphate isomerase activity

Added

obsolete glycolytic process through fructose-6-phosphate term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete glycolytic process through fructose-6-phosphate term replaced by glycolysis
obsolete glycolytic process through fructose-6-phosphate definition “OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
obsolete glycolytic process through fructose-6-phosphate deprecated true
obsolete glycolytic process through fructose-6-phosphate comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete glycolytic process through fructose-6-phosphate label “obsolete glycolytic process through fructose-6-phosphate”

obsolete glycolytic process through glucose-1-phosphate `http://purl.obolibrary.org/obo/GO_0061622`

Removed

obsolete glycolytic process through glucose-1-phosphate definition “The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
obsolete glycolytic process through glucose-1-phosphate label “glycolytic process through glucose-1-phosphate”
obsolete glycolytic process through glucose-1-phosphate EquivalentTo obsolete glycolytic process through glucose-6-phosphate and (has part some phosphoglucomutase activity)
obsolete glycolytic process through glucose-1-phosphate SubClassOf obsolete glycolytic process through glucose-6-phosphate
obsolete glycolytic process through glucose-1-phosphate SubClassOf has part some phosphoglucomutase activity

Added

obsolete glycolytic process through glucose-1-phosphate term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete glycolytic process through glucose-1-phosphate term replaced by glycolysis
obsolete glycolytic process through glucose-1-phosphate definition “OBSOLETE. The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
obsolete glycolytic process through glucose-1-phosphate deprecated true
obsolete glycolytic process through glucose-1-phosphate comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete glycolytic process through glucose-1-phosphate label “obsolete glycolytic process through glucose-1-phosphate”

obsolete glycolytic process through glucose-6-phosphate `http://purl.obolibrary.org/obo/GO_0061620`

Removed

obsolete glycolytic process through glucose-6-phosphate definition “The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
obsolete glycolytic process through glucose-6-phosphate label “glycolytic process through glucose-6-phosphate”
obsolete glycolytic process through glucose-6-phosphate EquivalentTo obsolete glycolytic process through fructose-6-phosphate and (has part some glucose-6-phosphate isomerase activity) and (has intermediate some alpha-D-glucose 6-phosphate(2-))
obsolete glycolytic process through glucose-6-phosphate SubClassOf obsolete glycolytic process through fructose-6-phosphate
obsolete glycolytic process through glucose-6-phosphate SubClassOf has part some glucose-6-phosphate isomerase activity
obsolete glycolytic process through glucose-6-phosphate SubClassOf has intermediate some alpha-D-glucose 6-phosphate(2-)

Added

obsolete glycolytic process through glucose-6-phosphate term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete glycolytic process through glucose-6-phosphate term replaced by glycolysis
obsolete glycolytic process through glucose-6-phosphate definition “OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP.”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
obsolete glycolytic process through glucose-6-phosphate deprecated true
obsolete glycolytic process through glucose-6-phosphate comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete glycolytic process through glucose-6-phosphate label “obsolete glycolytic process through glucose-6-phosphate”

obsolete glycoprotein-specific chaperone activity `http://purl.obolibrary.org/obo/GO_0003759`

Added

obsolete glycoprotein-specific chaperone activity term tracker item “https://github.com/geneontology/go-ontology/issues/32494”^^anyURI

obsolete glycyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006426`

Removed

obsolete glycyl-tRNA aminoacylation definition “The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of a glycine-accepting tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete glycyl-tRNA aminoacylation label “glycyl-tRNA aminoacylation”
obsolete glycyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete glycyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete glycyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete glycyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete glycyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of a glycine-accepting tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete glycyl-tRNA aminoacylation deprecated true
obsolete glycyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004820 glycine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete glycyl-tRNA aminoacylation label “obsolete glycyl-tRNA aminoacylation”

obsolete heptadecane metabolic process `http://purl.obolibrary.org/obo/GO_1900635`

Removed

obsolete heptadecane metabolic process conformsTo metabolic_process.yaml

obsolete heterochromatin domain `http://purl.obolibrary.org/obo/GO_1990343`

Removed

obsolete heterochromatin domain definition “A region of heterochromatin that is formed dynamically under specific growth conditions by a process that requires RNAi, and is enriched in histone H3 methylated on lysine 9 (H3K9me).”
- has cross-reference “PMID:23151475”
- has cross-reference “PMID:24210919”
obsolete heterochromatin domain comment “An example of this type of heterochromatin is found in Schizosaccharomyces pombe, where heterochromatin domains preferentially assemble at sexual differentiation genes and retrotransposons.”
obsolete heterochromatin domain label “heterochromatin domain”
obsolete heterochromatin domain SubClassOf heterochromatin
obsolete heterochromatin domain SubClassOf in taxon some cellular organisms

Added

obsolete heterochromatin domain term tracker item “https://github.com/geneontology/go-ontology/issues/26839”^^anyURI
obsolete heterochromatin domain consider heterochromatin
obsolete heterochromatin domain definition “OBSOLETE. A region of heterochromatin that is formed dynamically under specific growth conditions by a process that requires RNAi, and is enriched in histone H3 methylated on lysine 9 (H3K9me).”
- has cross-reference “PMID:23151475”
- has cross-reference “PMID:24210919”
obsolete heterochromatin domain deprecated true
obsolete heterochromatin domain comment “The reason for obsoletion is that this term was added in error.”
obsolete heterochromatin domain label “obsolete heterochromatin domain”

obsolete histidyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006427`

Removed

obsolete histidyl-tRNA aminoacylation definition “The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. The histidyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’‘-OH group of a histidine-accetping tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete histidyl-tRNA aminoacylation label “histidyl-tRNA aminoacylation”
obsolete histidyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete histidyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete histidyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete histidyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete histidyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. The histidyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’‘-OH group of a histidine-accetping tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete histidyl-tRNA aminoacylation deprecated true
obsolete histidyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004821 histidine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete histidyl-tRNA aminoacylation label “obsolete histidyl-tRNA aminoacylation”

obsolete integral component of phagophore assembly site membrane `http://purl.obolibrary.org/obo/GO_0097634`

Removed

obsolete integral component of phagophore assembly site membrane term replaced by obsolete phagophore assembly site membrane

Added

obsolete integral component of phagophore assembly site membrane term replaced by phagophore membrane

obsolete intrinsic component of phagophore assembly site membrane `http://purl.obolibrary.org/obo/GO_0097633`

Removed

obsolete intrinsic component of phagophore assembly site membrane term replaced by obsolete phagophore assembly site membrane

Added

obsolete intrinsic component of phagophore assembly site membrane term replaced by phagophore membrane

obsolete iprodione metabolic process `http://purl.obolibrary.org/obo/GO_0018922`

Removed

obsolete iprodione metabolic process conformsTo metabolic_process.yaml

obsolete isoleucyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006428`

Removed

obsolete isoleucyl-tRNA aminoacylation definition “The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a isoleucine-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete isoleucyl-tRNA aminoacylation label “isoleucyl-tRNA aminoacylation”
obsolete isoleucyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete isoleucyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete isoleucyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete isoleucyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete isoleucyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a isoleucine-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete isoleucyl-tRNA aminoacylation deprecated true
obsolete isoleucyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004822 isoleucine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete isoleucyl-tRNA aminoacylation label “obsolete isoleucyl-tRNA aminoacylation”

obsolete isoprene biosynthetic process `http://purl.obolibrary.org/obo/GO_0043612`

Removed

obsolete isoprene biosynthetic process conformsTo biosynthetic_process.yaml

obsolete isoprene metabolic process `http://purl.obolibrary.org/obo/GO_0043611`

Removed

obsolete isoprene metabolic process conformsTo metabolic_process.yaml

obsolete lectin-type holdase activity `http://purl.obolibrary.org/obo/GO_7770116`

Added

Class: obsolete lectin-type holdase activity
obsolete lectin-type holdase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32494”^^anyURI
obsolete lectin-type holdase activity term replaced by unfolded protein holdase activity
obsolete lectin-type holdase activity created by “ai4c-agent”
obsolete lectin-type holdase activity creation date “2026-08-26T21:57:40Z”
obsolete lectin-type holdase activity has exact synonym “carbohydrate-binding holdase”
obsolete lectin-type holdase activity has_obo_namespace “molecular_function”
obsolete lectin-type holdase activity has_related_synonym “lectin chaperone”
obsolete lectin-type holdase activity id “GO:7770116”
obsolete lectin-type holdase activity definition “OBSOLETE. A holdase activity that additionally recognizes a specific glycan structure on a protein via a lectin domain, and prevents aggregation of the protein until it is correctly folded.”
- has cross-reference “PMID:16467570”
obsolete lectin-type holdase activity deprecated true
obsolete lectin-type holdase activity comment “The reason for obsoletion is that this term was added in error.”
obsolete lectin-type holdase activity label “obsolete lectin-type holdase activity”

obsolete leucyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006429`

Removed

obsolete leucyl-tRNA aminoacylation definition “The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. The leucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a leucine-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete leucyl-tRNA aminoacylation label “leucyl-tRNA aminoacylation”
obsolete leucyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete leucyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete leucyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete leucyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete leucyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. The leucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a leucine-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete leucyl-tRNA aminoacylation deprecated true
obsolete leucyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004823 leucine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete leucyl-tRNA aminoacylation label “obsolete leucyl-tRNA aminoacylation”

obsolete ligand-dependent thyroid hormone receptor interactor activity `http://purl.obolibrary.org/obo/GO_0016923`

Removed

obsolete ligand-dependent thyroid hormone receptor interactor activity consider obsolete nuclear thyroid hormone receptor binding

Added

obsolete ligand-dependent thyroid hormone receptor interactor activity term tracker item “https://github.com/geneontology/go-ontology/issues/32475”^^anyURI
obsolete ligand-dependent thyroid hormone receptor interactor activity consider nuclear receptor binding

obsolete lipid X metabolic process `http://purl.obolibrary.org/obo/GO_2001289`

Removed

obsolete lipid X metabolic process conformsTo metabolic_process.yaml
obsolete lipid X metabolic process definition “The chemical reactions and pathways involving lipid X, 2,3-diacylglucosamine 1-phosphate.”
- has cross-reference “GOC:obol”
obsolete lipid X metabolic process label “lipid X metabolic process”
obsolete lipid X metabolic process EquivalentTo metabolic process and (has primary input or output some lipid X(2-))
obsolete lipid X metabolic process SubClassOf amino sugar metabolic process
obsolete lipid X metabolic process SubClassOf organophosphate metabolic process
obsolete lipid X metabolic process SubClassOf has primary input or output some lipid X(2-)

Added

obsolete lipid X metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32273”^^anyURI
obsolete lipid X metabolic process definition “OBSOLETE. The chemical reactions and pathways involving lipid X, 2,3-diacylglucosamine 1-phosphate.”
- has cross-reference “GOC:obol”
obsolete lipid X metabolic process deprecated true
obsolete lipid X metabolic process comment “The reason for obsoletion is that this term was made in error and is an unnecessary grouping term.”
obsolete lipid X metabolic process label “obsolete lipid X metabolic process”

obsolete lipoate biosynthetic process `http://purl.obolibrary.org/obo/GO_0009107`

Removed

obsolete lipoate biosynthetic process conformsTo biosynthetic_process.yaml
obsolete lipoate biosynthetic process definition “The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.”
- has cross-reference “GOC:ai”
- has cross-reference “ISBN:0198506732”
obsolete lipoate biosynthetic process label “lipoate biosynthetic process”
obsolete lipoate biosynthetic process EquivalentTo biosynthetic process and (has primary output some lipoate)
obsolete lipoate biosynthetic process SubClassOf fatty acid biosynthetic process
obsolete lipoate biosynthetic process SubClassOf lipoate metabolic process
obsolete lipoate biosynthetic process SubClassOf sulfur compound biosynthetic process
obsolete lipoate biosynthetic process SubClassOf has primary output some lipoate

Added

obsolete lipoate biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/32418”^^anyURI
obsolete lipoate biosynthetic process term replaced by protein lipoylation
obsolete lipoate biosynthetic process definition “OBSOLETE. The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.”
- has cross-reference “GOC:ai”
- has cross-reference “ISBN:0198506732”
obsolete lipoate biosynthetic process deprecated true
obsolete lipoate biosynthetic process comment “The reason for obsoletion is that the term usage has been inconsistent.”
obsolete lipoate biosynthetic process label “obsolete lipoate biosynthetic process”

obsolete lysyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006430`

Removed

obsolete lysyl-tRNA aminoacylation definition “The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. The lysyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of a lysine-accetping tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete lysyl-tRNA aminoacylation label “lysyl-tRNA aminoacylation”
obsolete lysyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete lysyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete lysyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete lysyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete lysyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. The lysyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of a lysine-accetping tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete lysyl-tRNA aminoacylation deprecated true
obsolete lysyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004824 lysine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete lysyl-tRNA aminoacylation label “obsolete lysyl-tRNA aminoacylation”

obsolete macromolecule depalmitoylation `http://purl.obolibrary.org/obo/GO_0098734`

Removed

obsolete macromolecule depalmitoylation definition “The removal of palymitoyl groups from a macromolecule.”
- has cross-reference “GOC:dos”
obsolete macromolecule depalmitoylation label “macromolecule depalmitoylation”
obsolete macromolecule depalmitoylation SubClassOf macromolecule deacylation

Added

obsolete macromolecule depalmitoylation term tracker item “https://github.com/geneontology/go-ontology/issues/32290”^^anyURI
obsolete macromolecule depalmitoylation consider palmitoyl-(protein) hydrolase activity
obsolete macromolecule depalmitoylation consider palmitoyl hydrolase activity
obsolete macromolecule depalmitoylation definition “OBSOLETE. The removal of palymitoyl groups from a macromolecule.”
- has cross-reference “GOC:dos”
obsolete macromolecule depalmitoylation deprecated true
obsolete macromolecule depalmitoylation comment “The reason for obsoletion is that this term represents a molecular function, not a biological process. Consider instead annotating to the molecular function ‘palmitoyl hydrolase activity’ (GO:0098599), or, for protein substrates, ‘palmitoyl-(protein) hydrolase activity’ (GO:0008474).”
obsolete macromolecule depalmitoylation label “obsolete macromolecule depalmitoylation”

obsolete maintenance of bipolar cell polarity regulating cell shape `http://purl.obolibrary.org/obo/GO_0061305`

Removed

obsolete maintenance of bipolar cell polarity regulating cell shape definition “The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell.”
- has cross-reference “GOC:dph”
- has cross-reference “GOC:vw”
obsolete maintenance of bipolar cell polarity regulating cell shape label “maintenance of bipolar cell polarity regulating cell shape”
obsolete maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete establishment or maintenance of bipolar cell polarity regulating cell shape
obsolete maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

Added

obsolete maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI
obsolete maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity
obsolete maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell.”
- has cross-reference “GOC:dph”
- has cross-reference “GOC:vw”
obsolete maintenance of bipolar cell polarity regulating cell shape deprecated true
obsolete maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that these terms were added in error.”
obsolete maintenance of bipolar cell polarity regulating cell shape label “obsolete maintenance of bipolar cell polarity regulating cell shape”

obsolete maltoheptaose metabolic process `http://purl.obolibrary.org/obo/GO_2001122`

Removed

obsolete maltoheptaose metabolic process conformsTo metabolic_process.yaml

obsolete membrane addition at site of mitotic cytokinesis `http://purl.obolibrary.org/obo/GO_0061796`

Removed

obsolete membrane addition at site of mitotic cytokinesis conformsTo involved_in_x_y.yaml
obsolete membrane addition at site of mitotic cytokinesis definition “A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.”
- has cross-reference “GOC:dph”
- has cross-reference “GOC:vw”
obsolete membrane addition at site of mitotic cytokinesis label “membrane addition at site of mitotic cytokinesis”
obsolete membrane addition at site of mitotic cytokinesis EquivalentTo membrane addition at site of cytokinesis and (part of some mitotic cell cycle)
obsolete membrane addition at site of mitotic cytokinesis SubClassOf membrane addition at site of cytokinesis
obsolete membrane addition at site of mitotic cytokinesis SubClassOf mitotic cytokinetic process
obsolete membrane addition at site of mitotic cytokinesis SubClassOf in taxon some Eukaryota

Added

obsolete membrane addition at site of mitotic cytokinesis term tracker item “https://github.com/geneontology/go-ontology/issues/31687”^^anyURI
obsolete membrane addition at site of mitotic cytokinesis consider exocytosis
obsolete membrane addition at site of mitotic cytokinesis definition “OBSOLETE. A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.”
- has cross-reference “GOC:dph”
- has cross-reference “GOC:vw”
obsolete membrane addition at site of mitotic cytokinesis deprecated true
obsolete membrane addition at site of mitotic cytokinesis comment “The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.”
obsolete membrane addition at site of mitotic cytokinesis label “obsolete membrane addition at site of mitotic cytokinesis”

obsolete methanesulfonic acid metabolic process `http://purl.obolibrary.org/obo/GO_0018926`

Removed

obsolete methanesulfonic acid metabolic process conformsTo metabolic_process.yaml

obsolete methanophenazine metabolic process `http://purl.obolibrary.org/obo/GO_1900629`

Removed

obsolete methanophenazine metabolic process conformsTo metabolic_process.yaml

obsolete methionyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006431`

Removed

obsolete methionyl-tRNA aminoacylation definition “The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a methionine-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete methionyl-tRNA aminoacylation label “methionyl-tRNA aminoacylation”
obsolete methionyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete methionyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete methionyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete methionyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete methionyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a methionine-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete methionyl-tRNA aminoacylation deprecated true
obsolete methionyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004825 methionine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete methionyl-tRNA aminoacylation label “obsolete methionyl-tRNA aminoacylation”

obsolete methyl fluoride metabolic process `http://purl.obolibrary.org/obo/GO_0018929`

Removed

obsolete methyl fluoride metabolic process conformsTo metabolic_process.yaml

obsolete methyl tert-butyl ether metabolic process `http://purl.obolibrary.org/obo/GO_0018906`

Removed

obsolete methyl tert-butyl ether metabolic process conformsTo metabolic_process.yaml

obsolete mitochondrial alanyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070143`

Removed

obsolete mitochondrial alanyl-tRNA aminoacylation definition “The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial alanyl-tRNA aminoacylation label “mitochondrial alanyl-tRNA aminoacylation”
obsolete mitochondrial alanyl-tRNA aminoacylation EquivalentTo obsolete alanyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial alanyl-tRNA aminoacylation SubClassOf obsolete alanyl-tRNA aminoacylation
obsolete mitochondrial alanyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial alanyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial alanyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial alanyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial alanyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial alanyl-tRNA aminoacylation deprecated true
obsolete mitochondrial alanyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004813 alanine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial alanyl-tRNA aminoacylation label “obsolete mitochondrial alanyl-tRNA aminoacylation”

obsolete mitochondrial arginyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070144`

Removed

obsolete mitochondrial arginyl-tRNA aminoacylation definition “The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial arginyl-tRNA aminoacylation label “mitochondrial arginyl-tRNA aminoacylation”
obsolete mitochondrial arginyl-tRNA aminoacylation EquivalentTo obsolete arginyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial arginyl-tRNA aminoacylation SubClassOf obsolete arginyl-tRNA aminoacylation
obsolete mitochondrial arginyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial arginyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial arginyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial arginyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial arginyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial arginyl-tRNA aminoacylation deprecated true
obsolete mitochondrial arginyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004814 arginine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial arginyl-tRNA aminoacylation label “obsolete mitochondrial arginyl-tRNA aminoacylation”

obsolete mitochondrial asparaginyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070145`

Removed

obsolete mitochondrial asparaginyl-tRNA aminoacylation definition “The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial asparaginyl-tRNA aminoacylation label “mitochondrial asparaginyl-tRNA aminoacylation”
obsolete mitochondrial asparaginyl-tRNA aminoacylation EquivalentTo obsolete asparaginyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial asparaginyl-tRNA aminoacylation SubClassOf obsolete asparaginyl-tRNA aminoacylation
obsolete mitochondrial asparaginyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial asparaginyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial asparaginyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial asparaginyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial asparaginyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial asparaginyl-tRNA aminoacylation deprecated true
obsolete mitochondrial asparaginyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004816 asparagine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial asparaginyl-tRNA aminoacylation label “obsolete mitochondrial asparaginyl-tRNA aminoacylation”

obsolete mitochondrial aspartyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070146`

Removed

obsolete mitochondrial aspartyl-tRNA aminoacylation definition “The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial aspartyl-tRNA aminoacylation label “mitochondrial aspartyl-tRNA aminoacylation”
obsolete mitochondrial aspartyl-tRNA aminoacylation EquivalentTo obsolete aspartyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial aspartyl-tRNA aminoacylation SubClassOf obsolete aspartyl-tRNA aminoacylation
obsolete mitochondrial aspartyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial aspartyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial aspartyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial aspartyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial aspartyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial aspartyl-tRNA aminoacylation deprecated true
obsolete mitochondrial aspartyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004815 aspartate-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial aspartyl-tRNA aminoacylation label “obsolete mitochondrial aspartyl-tRNA aminoacylation”

obsolete mitochondrial cysteinyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070147`

Removed

obsolete mitochondrial cysteinyl-tRNA aminoacylation definition “The process of coupling L-cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial cysteinyl-tRNA aminoacylation label “mitochondrial cysteinyl-tRNA aminoacylation”
obsolete mitochondrial cysteinyl-tRNA aminoacylation EquivalentTo obsolete cysteinyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial cysteinyl-tRNA aminoacylation SubClassOf obsolete cysteinyl-tRNA aminoacylation
obsolete mitochondrial cysteinyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial cysteinyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial cysteinyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial cysteinyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial cysteinyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling L-cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial cysteinyl-tRNA aminoacylation deprecated true
obsolete mitochondrial cysteinyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004817 cysteine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial cysteinyl-tRNA aminoacylation label “obsolete mitochondrial cysteinyl-tRNA aminoacylation”

obsolete mitochondrial glutaminyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070148`

Removed

obsolete mitochondrial glutaminyl-tRNA aminoacylation definition “The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial glutaminyl-tRNA aminoacylation label “mitochondrial glutaminyl-tRNA aminoacylation”
obsolete mitochondrial glutaminyl-tRNA aminoacylation EquivalentTo obsolete glutaminyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial glutaminyl-tRNA aminoacylation SubClassOf obsolete glutaminyl-tRNA aminoacylation
obsolete mitochondrial glutaminyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial glutaminyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial glutaminyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial glutaminyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial glutaminyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial glutaminyl-tRNA aminoacylation deprecated true
obsolete mitochondrial glutaminyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function and adds nothing beyond it. Note that the counterpart is not a glutamine-tRNA ligase in most eukaryotes: mitochondria generally encode no mitochondrial GlnRS, and mt-tRNA(Gln) is charged indirectly by a non-discriminating mitochondrial GluRS followed by the GatCAB amidotransferase, which is GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. GO:0004819 glutamine-tRNA ligase activity applies only where a mitochondrial GlnRS is present. The biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial glutaminyl-tRNA aminoacylation label “obsolete mitochondrial glutaminyl-tRNA aminoacylation”

obsolete mitochondrial glutamyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070149`

Removed

obsolete mitochondrial glutamyl-tRNA aminoacylation definition “The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial glutamyl-tRNA aminoacylation label “mitochondrial glutamyl-tRNA aminoacylation”
obsolete mitochondrial glutamyl-tRNA aminoacylation EquivalentTo obsolete glutamyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial glutamyl-tRNA aminoacylation SubClassOf obsolete glutamyl-tRNA aminoacylation
obsolete mitochondrial glutamyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial glutamyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial glutamyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial glutamyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial glutamyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial glutamyl-tRNA aminoacylation deprecated true
obsolete mitochondrial glutamyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004818 glutamate-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial glutamyl-tRNA aminoacylation label “obsolete mitochondrial glutamyl-tRNA aminoacylation”

obsolete mitochondrial glycyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070150`

Removed

obsolete mitochondrial glycyl-tRNA aminoacylation definition “The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial glycyl-tRNA aminoacylation label “mitochondrial glycyl-tRNA aminoacylation”
obsolete mitochondrial glycyl-tRNA aminoacylation EquivalentTo obsolete glycyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial glycyl-tRNA aminoacylation SubClassOf obsolete glycyl-tRNA aminoacylation
obsolete mitochondrial glycyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial glycyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial glycyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial glycyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial glycyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial glycyl-tRNA aminoacylation deprecated true
obsolete mitochondrial glycyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004820 glycine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial glycyl-tRNA aminoacylation label “obsolete mitochondrial glycyl-tRNA aminoacylation”

obsolete mitochondrial histidyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070151`

Removed

obsolete mitochondrial histidyl-tRNA aminoacylation definition “The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial histidyl-tRNA aminoacylation label “mitochondrial histidyl-tRNA aminoacylation”
obsolete mitochondrial histidyl-tRNA aminoacylation EquivalentTo obsolete histidyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial histidyl-tRNA aminoacylation SubClassOf obsolete histidyl-tRNA aminoacylation
obsolete mitochondrial histidyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial histidyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial histidyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial histidyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial histidyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial histidyl-tRNA aminoacylation deprecated true
obsolete mitochondrial histidyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004821 histidine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial histidyl-tRNA aminoacylation label “obsolete mitochondrial histidyl-tRNA aminoacylation”

obsolete mitochondrial isoleucyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070152`

Removed

obsolete mitochondrial isoleucyl-tRNA aminoacylation definition “The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial isoleucyl-tRNA aminoacylation label “mitochondrial isoleucyl-tRNA aminoacylation”
obsolete mitochondrial isoleucyl-tRNA aminoacylation EquivalentTo obsolete isoleucyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial isoleucyl-tRNA aminoacylation SubClassOf obsolete isoleucyl-tRNA aminoacylation
obsolete mitochondrial isoleucyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial isoleucyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial isoleucyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial isoleucyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial isoleucyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial isoleucyl-tRNA aminoacylation deprecated true
obsolete mitochondrial isoleucyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004822 isoleucine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial isoleucyl-tRNA aminoacylation label “obsolete mitochondrial isoleucyl-tRNA aminoacylation”

obsolete mitochondrial leucyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070153`

Removed

obsolete mitochondrial leucyl-tRNA aminoacylation definition “The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial leucyl-tRNA aminoacylation label “mitochondrial leucyl-tRNA aminoacylation”
obsolete mitochondrial leucyl-tRNA aminoacylation EquivalentTo obsolete leucyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial leucyl-tRNA aminoacylation SubClassOf obsolete leucyl-tRNA aminoacylation
obsolete mitochondrial leucyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial leucyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial leucyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial leucyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial leucyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial leucyl-tRNA aminoacylation deprecated true
obsolete mitochondrial leucyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004823 leucine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial leucyl-tRNA aminoacylation label “obsolete mitochondrial leucyl-tRNA aminoacylation”

obsolete mitochondrial lysyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070154`

Removed

obsolete mitochondrial lysyl-tRNA aminoacylation definition “The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial lysyl-tRNA aminoacylation label “mitochondrial lysyl-tRNA aminoacylation”
obsolete mitochondrial lysyl-tRNA aminoacylation EquivalentTo obsolete lysyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial lysyl-tRNA aminoacylation SubClassOf obsolete lysyl-tRNA aminoacylation
obsolete mitochondrial lysyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial lysyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial lysyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial lysyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial lysyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial lysyl-tRNA aminoacylation deprecated true
obsolete mitochondrial lysyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004824 lysine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial lysyl-tRNA aminoacylation label “obsolete mitochondrial lysyl-tRNA aminoacylation”

obsolete mitochondrial methionyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070155`

Removed

obsolete mitochondrial methionyl-tRNA aminoacylation definition “The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial methionyl-tRNA aminoacylation label “mitochondrial methionyl-tRNA aminoacylation”
obsolete mitochondrial methionyl-tRNA aminoacylation EquivalentTo obsolete methionyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial methionyl-tRNA aminoacylation SubClassOf obsolete methionyl-tRNA aminoacylation
obsolete mitochondrial methionyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial methionyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial methionyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial methionyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial methionyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial methionyl-tRNA aminoacylation deprecated true
obsolete mitochondrial methionyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004825 methionine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial methionyl-tRNA aminoacylation label “obsolete mitochondrial methionyl-tRNA aminoacylation”

obsolete mitochondrial phenylalanyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070156`

Removed

obsolete mitochondrial phenylalanyl-tRNA aminoacylation definition “The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial phenylalanyl-tRNA aminoacylation label “mitochondrial phenylalanyl-tRNA aminoacylation”
obsolete mitochondrial phenylalanyl-tRNA aminoacylation EquivalentTo obsolete phenylalanyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial phenylalanyl-tRNA aminoacylation SubClassOf obsolete phenylalanyl-tRNA aminoacylation
obsolete mitochondrial phenylalanyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial phenylalanyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial phenylalanyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial phenylalanyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial phenylalanyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial phenylalanyl-tRNA aminoacylation deprecated true
obsolete mitochondrial phenylalanyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004826 phenylalanine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial phenylalanyl-tRNA aminoacylation label “obsolete mitochondrial phenylalanyl-tRNA aminoacylation”

obsolete mitochondrial prolyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070157`

Removed

obsolete mitochondrial prolyl-tRNA aminoacylation definition “The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial prolyl-tRNA aminoacylation label “mitochondrial prolyl-tRNA aminoacylation”
obsolete mitochondrial prolyl-tRNA aminoacylation EquivalentTo obsolete prolyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial prolyl-tRNA aminoacylation SubClassOf obsolete prolyl-tRNA aminoacylation
obsolete mitochondrial prolyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial prolyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial prolyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial prolyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial prolyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial prolyl-tRNA aminoacylation deprecated true
obsolete mitochondrial prolyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004827 proline-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial prolyl-tRNA aminoacylation label “obsolete mitochondrial prolyl-tRNA aminoacylation”

obsolete mitochondrial protein-transporting ATPase activity `http://purl.obolibrary.org/obo/GO_0008566`

Removed

obsolete mitochondrial protein-transporting ATPase activity definition “Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.”
- has cross-reference “EC:7.4.2.3”
obsolete mitochondrial protein-transporting ATPase activity comment “See also the cellular component term ‘mitochondrial inner membrane presequence translocase complex ; GO:0005744’.”
obsolete mitochondrial protein-transporting ATPase activity label “mitochondrial protein-transporting ATPase activity”
obsolete mitochondrial protein-transporting ATPase activity EquivalentTo protein-transporting ATPase activity and (occurs in some mitochondrion)
obsolete mitochondrial protein-transporting ATPase activity SubClassOf protein-transporting ATPase activity
obsolete mitochondrial protein-transporting ATPase activity SubClassOf occurs in some mitochondrion

Added

obsolete mitochondrial protein-transporting ATPase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32393”^^anyURI
obsolete mitochondrial protein-transporting ATPase activity definition “OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.”
- has cross-reference “EC:7.4.2.3”
obsolete mitochondrial protein-transporting ATPase activity deprecated true
obsolete mitochondrial protein-transporting ATPase activity comment “The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent.”
obsolete mitochondrial protein-transporting ATPase activity label “obsolete mitochondrial protein-transporting ATPase activity”

obsolete mitochondrial seryl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070158`

Removed

obsolete mitochondrial seryl-tRNA aminoacylation definition “The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial seryl-tRNA aminoacylation label “mitochondrial seryl-tRNA aminoacylation”
obsolete mitochondrial seryl-tRNA aminoacylation EquivalentTo obsolete seryl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial seryl-tRNA aminoacylation SubClassOf obsolete seryl-tRNA aminoacylation
obsolete mitochondrial seryl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial seryl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial seryl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial seryl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial seryl-tRNA aminoacylation definition “OBSOLETE. The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial seryl-tRNA aminoacylation deprecated true
obsolete mitochondrial seryl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004828 serine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial seryl-tRNA aminoacylation label “obsolete mitochondrial seryl-tRNA aminoacylation”

obsolete mitochondrial threonyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070159`

Removed

obsolete mitochondrial threonyl-tRNA aminoacylation definition “The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial threonyl-tRNA aminoacylation label “mitochondrial threonyl-tRNA aminoacylation”
obsolete mitochondrial threonyl-tRNA aminoacylation EquivalentTo obsolete threonyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial threonyl-tRNA aminoacylation SubClassOf obsolete threonyl-tRNA aminoacylation
obsolete mitochondrial threonyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial threonyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial threonyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial threonyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial threonyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial threonyl-tRNA aminoacylation deprecated true
obsolete mitochondrial threonyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004829 threonine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial threonyl-tRNA aminoacylation label “obsolete mitochondrial threonyl-tRNA aminoacylation”

obsolete mitochondrial tryptophanyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070183`

Removed

obsolete mitochondrial tryptophanyl-tRNA aminoacylation definition “The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial tryptophanyl-tRNA aminoacylation label “mitochondrial tryptophanyl-tRNA aminoacylation”
obsolete mitochondrial tryptophanyl-tRNA aminoacylation EquivalentTo obsolete tryptophanyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial tryptophanyl-tRNA aminoacylation SubClassOf obsolete tryptophanyl-tRNA aminoacylation
obsolete mitochondrial tryptophanyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial tryptophanyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial tryptophanyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial tryptophanyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial tryptophanyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial tryptophanyl-tRNA aminoacylation deprecated true
obsolete mitochondrial tryptophanyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004830 tryptophan-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial tryptophanyl-tRNA aminoacylation label “obsolete mitochondrial tryptophanyl-tRNA aminoacylation”

obsolete mitochondrial tyrosyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070184`

Removed

obsolete mitochondrial tyrosyl-tRNA aminoacylation definition “The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial tyrosyl-tRNA aminoacylation label “mitochondrial tyrosyl-tRNA aminoacylation”
obsolete mitochondrial tyrosyl-tRNA aminoacylation EquivalentTo obsolete tyrosyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial tyrosyl-tRNA aminoacylation SubClassOf obsolete tyrosyl-tRNA aminoacylation
obsolete mitochondrial tyrosyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial tyrosyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial tyrosyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial tyrosyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial tyrosyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial tyrosyl-tRNA aminoacylation deprecated true
obsolete mitochondrial tyrosyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004831 tyrosine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial tyrosyl-tRNA aminoacylation label “obsolete mitochondrial tyrosyl-tRNA aminoacylation”

obsolete mitochondrial valyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0070185`

Removed

obsolete mitochondrial valyl-tRNA aminoacylation definition “The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial valyl-tRNA aminoacylation label “mitochondrial valyl-tRNA aminoacylation”
obsolete mitochondrial valyl-tRNA aminoacylation EquivalentTo obsolete valyl-tRNA aminoacylation and (occurs in some mitochondrion)
obsolete mitochondrial valyl-tRNA aminoacylation SubClassOf obsolete valyl-tRNA aminoacylation
obsolete mitochondrial valyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial valyl-tRNA aminoacylation SubClassOf in taxon some Eukaryota

Added

obsolete mitochondrial valyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete mitochondrial valyl-tRNA aminoacylation term replaced by tRNA aminoacylation for mitochondrial protein translation
obsolete mitochondrial valyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:mcc”
obsolete mitochondrial valyl-tRNA aminoacylation deprecated true
obsolete mitochondrial valyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004832 valine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0070127 tRNA aminoacylation for mitochondrial protein translation.”
obsolete mitochondrial valyl-tRNA aminoacylation label “obsolete mitochondrial valyl-tRNA aminoacylation”

obsolete monounsaturated fatty acid metabolic process `http://purl.obolibrary.org/obo/GO_1903964`

Removed

obsolete monounsaturated fatty acid metabolic process conformsTo metabolic_process.yaml

obsolete naphthalenesulfonate metabolic process `http://purl.obolibrary.org/obo/GO_0018984`

Removed

obsolete naphthalenesulfonate metabolic process conformsTo metabolic_process.yaml

obsolete negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900942`

Removed

obsolete negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of 17-methylnonadec-1-ene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900957`

Removed

obsolete negative regulation of 17-methylnonadec-1-ene biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of 18-methylnonadec-1-ene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900951`

Removed

obsolete negative regulation of 18-methylnonadec-1-ene biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of cordyol C biosynthetic process `http://purl.obolibrary.org/obo/GO_1900862`

Removed

obsolete negative regulation of cordyol C biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of diorcinol biosynthetic process `http://purl.obolibrary.org/obo/GO_1900656`

Removed

obsolete negative regulation of diorcinol biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape `http://purl.obolibrary.org/obo/GO_2000750`

Removed

obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape conformsTo negative_regulation.yaml
obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape definition “Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.”
- has cross-reference “GOC:mah”
obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape label “negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape”
obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape EquivalentTo biological regulation and (negatively regulates some obsolete establishment or maintenance of bipolar cell polarity regulating cell shape)
obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape
obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf negative regulation of establishment or maintenance of cell polarity regulating cell shape
obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms
obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf negatively regulates some obsolete establishment or maintenance of bipolar cell polarity regulating cell shape

Added

obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI
obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity
obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.”
- has cross-reference “GOC:mah”
obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape deprecated true
obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”
obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape label “obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape”

obsolete negative regulation of glycolytic process through fructose-6-phosphate `http://purl.obolibrary.org/obo/GO_1904539`

Removed

obsolete negative regulation of glycolytic process through fructose-6-phosphate definition “Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
- has cross-reference “GOC:TermGenie”
obsolete negative regulation of glycolytic process through fructose-6-phosphate label “negative regulation of glycolytic process through fructose-6-phosphate”
obsolete negative regulation of glycolytic process through fructose-6-phosphate EquivalentTo biological regulation and (negatively regulates some obsolete glycolytic process through fructose-6-phosphate)
obsolete negative regulation of glycolytic process through fructose-6-phosphate SubClassOf negative regulation of glycolysis
obsolete negative regulation of glycolytic process through fructose-6-phosphate SubClassOf negatively regulates some obsolete glycolytic process through fructose-6-phosphate

Added

obsolete negative regulation of glycolytic process through fructose-6-phosphate term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete negative regulation of glycolytic process through fructose-6-phosphate term replaced by negative regulation of glycolysis
obsolete negative regulation of glycolytic process through fructose-6-phosphate definition “OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
- has cross-reference “GOC:TermGenie”
obsolete negative regulation of glycolytic process through fructose-6-phosphate deprecated true
obsolete negative regulation of glycolytic process through fructose-6-phosphate comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete negative regulation of glycolytic process through fructose-6-phosphate label “obsolete negative regulation of glycolytic process through fructose-6-phosphate”

obsolete negative regulation of isoprene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900948`

Removed

obsolete negative regulation of isoprene biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape `http://purl.obolibrary.org/obo/GO_0061362`

Removed

obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape definition “Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.”
- has cross-reference “GOC:dph”
obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape label “negative regulation of maintenance of bipolar cell polarity regulating cell shape”
obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of maintenance of bipolar cell polarity regulating cell shape
obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape
obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms
obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf negatively regulates some obsolete maintenance of bipolar cell polarity regulating cell shape

Added

obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI
obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity
obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.”
- has cross-reference “GOC:dph”
obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape deprecated true
obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”
obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape label “obsolete negative regulation of maintenance of bipolar cell polarity regulating cell shape”

obsolete negative regulation of nonadec-1-ene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900936`

Removed

obsolete negative regulation of nonadec-1-ene biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of octadecene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900915`

Removed

obsolete negative regulation of octadecene biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of palmitic acid catabolic process `http://purl.obolibrary.org/obo/GO_0106394`

Removed

obsolete negative regulation of palmitic acid catabolic process conformsTo negative_regulation.yaml

obsolete negative regulation of protein localization to mitochondrion `http://purl.obolibrary.org/obo/GO_1903748`

Removed

obsolete negative regulation of protein localization to mitochondrion term tracker item “https://github.com/geneontology/go-ontology/issues/30349”^^anyURI
obsolete negative regulation of protein localization to mitochondrion conformsTo negative_regulation.yaml
obsolete negative regulation of protein localization to mitochondrion definition “Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitochondrion.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “PMID:16857185”
- has cross-reference “GOC:TermGenie”
obsolete negative regulation of protein localization to mitochondrion label “negative regulation of protein localization to mitochondrion”
obsolete negative regulation of protein localization to mitochondrion EquivalentTo biological regulation and (negatively regulates some protein localization to mitochondrion)
obsolete negative regulation of protein localization to mitochondrion SubClassOf obsolete regulation of protein localization to mitochondrion
obsolete negative regulation of protein localization to mitochondrion SubClassOf negative regulation of protein localization
obsolete negative regulation of protein localization to mitochondrion SubClassOf negatively regulates some protein localization to mitochondrion

Added

obsolete negative regulation of protein localization to mitochondrion term tracker item “https://github.com/geneontology/go-ontology/issues/32107”^^anyURI
obsolete negative regulation of protein localization to mitochondrion definition “OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitochondrion.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “PMID:16857185”
- has cross-reference “GOC:TermGenie”
obsolete negative regulation of protein localization to mitochondrion deprecated true
obsolete negative regulation of protein localization to mitochondrion comment “The reason for obsoletion is that this term represents a phenotype and was added in error. Consider annotating to negative regulation of the specific process being regulated (e.g. negative regulation of mitophagy) or to a specific mitochondrial protein import pathway; if the underlying evidence is a readout or a phenotype, or the mechanism is unclear, consider removal rather than re-annotation.”
obsolete negative regulation of protein localization to mitochondrion label “obsolete negative regulation of protein localization to mitochondrion”

obsolete negative regulation of protein processing involved in protein targeting to mitochondrion `http://purl.obolibrary.org/obo/GO_1903217`

Removed

obsolete negative regulation of protein processing involved in protein targeting to mitochondrion term replaced by obsolete negative regulation of protein localization to mitochondrion

obsolete negative regulation of protein targeting to mitochondrion `http://purl.obolibrary.org/obo/GO_1903215`

Removed

obsolete negative regulation of protein targeting to mitochondrion term replaced by obsolete negative regulation of protein localization to mitochondrion

obsolete negative regulation of retrograde protein transport, ER to cytosol `http://purl.obolibrary.org/obo/GO_1904153`

Removed

obsolete negative regulation of retrograde protein transport, ER to cytosol definition “Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “GOC:PARL”
- has cross-reference “PMID:18555783”
- has cross-reference “GOC:bf”
- has cross-reference “GOC:TermGenie”
obsolete negative regulation of retrograde protein transport, ER to cytosol label “negative regulation of retrograde protein transport, ER to cytosol”
obsolete negative regulation of retrograde protein transport, ER to cytosol EquivalentTo biological regulation and (negatively regulates some retrograde protein transport, ER to cytosol)
obsolete negative regulation of retrograde protein transport, ER to cytosol SubClassOf negative regulation of protein transport
obsolete negative regulation of retrograde protein transport, ER to cytosol SubClassOf obsolete regulation of retrograde protein transport, ER to cytosol
obsolete negative regulation of retrograde protein transport, ER to cytosol SubClassOf negatively regulates some retrograde protein transport, ER to cytosol

Added

obsolete negative regulation of retrograde protein transport, ER to cytosol term tracker item “https://github.com/geneontology/go-ontology/issues/32525”^^anyURI
obsolete negative regulation of retrograde protein transport, ER to cytosol term replaced by negative regulation of ERAD pathway
obsolete negative regulation of retrograde protein transport, ER to cytosol definition “OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “GOC:PARL”
- has cross-reference “PMID:18555783”
- has cross-reference “GOC:bf”
- has cross-reference “GOC:TermGenie”
obsolete negative regulation of retrograde protein transport, ER to cytosol deprecated true
obsolete negative regulation of retrograde protein transport, ER to cytosol comment “The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent, the data from the paper for which the term was requested can be accurately described using reguation of ERAD pathway terms, and this term was added in error.”
obsolete negative regulation of retrograde protein transport, ER to cytosol label “obsolete negative regulation of retrograde protein transport, ER to cytosol”

obsolete negative regulation of tatiopterin biosynthetic process `http://purl.obolibrary.org/obo/GO_1900975`

Removed

obsolete negative regulation of tatiopterin biosynthetic process conformsTo negative_regulation.yaml

obsolete negative regulation of transcription from RNA polymerase II promoter by glucose `http://purl.obolibrary.org/obo/GO_0061987`

Removed

obsolete negative regulation of transcription from RNA polymerase II promoter by glucose definition “Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter.”
- has cross-reference “PMID:11875061”
obsolete negative regulation of transcription from RNA polymerase II promoter by glucose label “negative regulation of transcription from RNA polymerase II promoter by glucose”
obsolete negative regulation of transcription from RNA polymerase II promoter by glucose SubClassOf obsolete regulation of transcription from RNA polymerase II promoter by glucose
obsolete negative regulation of transcription from RNA polymerase II promoter by glucose SubClassOf negative regulation of transcription by glucose

Added

obsolete negative regulation of transcription from RNA polymerase II promoter by glucose term tracker item “https://github.com/geneontology/go-ontology/issues/21442”^^anyURI
obsolete negative regulation of transcription from RNA polymerase II promoter by glucose consider negative regulation of transcription by RNA polymerase II
obsolete negative regulation of transcription from RNA polymerase II promoter by glucose definition “OBSOLETE. Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter.”
- has cross-reference “PMID:11875061”
obsolete negative regulation of transcription from RNA polymerase II promoter by glucose deprecated true
obsolete negative regulation of transcription from RNA polymerase II promoter by glucose comment “The reason for obsoletion is that these terms represent GO-CAM models.”
obsolete negative regulation of transcription from RNA polymerase II promoter by glucose label “obsolete negative regulation of transcription from RNA polymerase II promoter by glucose”

obsolete nonadec-1-ene metabolic process `http://purl.obolibrary.org/obo/GO_1900876`

Removed

obsolete nonadec-1-ene metabolic process conformsTo metabolic_process.yaml

obsolete nuclear androgen receptor binding `http://purl.obolibrary.org/obo/GO_0050681`

Removed

obsolete nuclear androgen receptor binding never in taxon Archaea
obsolete nuclear androgen receptor binding never in taxon Bacteria
obsolete nuclear androgen receptor binding never in taxon Fungi
obsolete nuclear androgen receptor binding conformsTo binding.yaml
obsolete nuclear androgen receptor binding definition “Binding to a nuclear androgen receptor.”
- has cross-reference “GOC:ai”
obsolete nuclear androgen receptor binding label “nuclear androgen receptor binding”
obsolete nuclear androgen receptor binding EquivalentTo binding and (has primary input some androgen receptor)
obsolete nuclear androgen receptor binding SubClassOf nuclear receptor binding
obsolete nuclear androgen receptor binding SubClassOf not (in taxon some Archaea)
obsolete nuclear androgen receptor binding SubClassOf not (in taxon some Bacteria)
obsolete nuclear androgen receptor binding SubClassOf not (in taxon some Fungi)
obsolete nuclear androgen receptor binding SubClassOf has primary input some androgen receptor

Added

obsolete nuclear androgen receptor binding term tracker item “https://github.com/geneontology/go-ontology/issues/32475”^^anyURI
obsolete nuclear androgen receptor binding consider nuclear receptor binding
obsolete nuclear androgen receptor binding definition “OBSOLETE. Binding to a nuclear androgen receptor.”
- has cross-reference “GOC:ai”
obsolete nuclear androgen receptor binding deprecated true
obsolete nuclear androgen receptor binding comment “The reason for obsoletion is that this term represents a gene product. Better to annotate with GO:0016922 nuclear receptor binding and androgen receptor as ‘has_input’.”
obsolete nuclear androgen receptor binding label “obsolete nuclear androgen receptor binding”

obsolete nuclear cortisol receptor binding `http://purl.obolibrary.org/obo/GO_0031961`

Removed

obsolete nuclear cortisol receptor binding never in taxon Archaea
obsolete nuclear cortisol receptor binding never in taxon Bacteria
obsolete nuclear cortisol receptor binding never in taxon Fungi
obsolete nuclear cortisol receptor binding definition “Binding to a nuclear cortisol receptor.”
- has cross-reference “GOC:mah”
- has cross-reference “PMID:12511169”
obsolete nuclear cortisol receptor binding label “nuclear cortisol receptor binding”
obsolete nuclear cortisol receptor binding SubClassOf obsolete nuclear glucocorticoid receptor binding
obsolete nuclear cortisol receptor binding SubClassOf not (in taxon some Archaea)
obsolete nuclear cortisol receptor binding SubClassOf not (in taxon some Bacteria)
obsolete nuclear cortisol receptor binding SubClassOf not (in taxon some Fungi)

Added

obsolete nuclear cortisol receptor binding term tracker item “https://github.com/geneontology/go-ontology/issues/32475”^^anyURI
obsolete nuclear cortisol receptor binding consider nuclear receptor binding
obsolete nuclear cortisol receptor binding definition “OBSOLETE. Binding to a nuclear cortisol receptor.”
- has cross-reference “GOC:mah”
- has cross-reference “PMID:12511169”
obsolete nuclear cortisol receptor binding deprecated true
obsolete nuclear cortisol receptor binding comment “The reason for obsoletion is that this term represents a gene product. Better to annotate with GO:0016922 nuclear receptor binding and cortisol receptor as ‘has_input’.”
obsolete nuclear cortisol receptor binding label “obsolete nuclear cortisol receptor binding”

obsolete nuclear estrogen receptor binding `http://purl.obolibrary.org/obo/GO_0030331`

Removed

obsolete nuclear estrogen receptor binding never in taxon Archaea
obsolete nuclear estrogen receptor binding never in taxon Bacteria
obsolete nuclear estrogen receptor binding never in taxon Fungi
obsolete nuclear estrogen receptor binding conformsTo binding.yaml
obsolete nuclear estrogen receptor binding definition “Binding to a nuclear estrogen receptor.”
- has cross-reference “GOC:ai”
obsolete nuclear estrogen receptor binding label “nuclear estrogen receptor binding”
obsolete nuclear estrogen receptor binding EquivalentTo binding and (has primary input some estrogen receptor)
obsolete nuclear estrogen receptor binding SubClassOf nuclear receptor binding
obsolete nuclear estrogen receptor binding SubClassOf not (in taxon some Archaea)
obsolete nuclear estrogen receptor binding SubClassOf not (in taxon some Bacteria)
obsolete nuclear estrogen receptor binding SubClassOf not (in taxon some Fungi)
obsolete nuclear estrogen receptor binding SubClassOf has primary input some estrogen receptor

Added

obsolete nuclear estrogen receptor binding term tracker item “https://github.com/geneontology/go-ontology/issues/32475”^^anyURI
obsolete nuclear estrogen receptor binding consider nuclear receptor binding
obsolete nuclear estrogen receptor binding definition “OBSOLETE. Binding to a nuclear estrogen receptor.”
- has cross-reference “GOC:ai”
obsolete nuclear estrogen receptor binding deprecated true
obsolete nuclear estrogen receptor binding comment “The reason for obsoletion is that this term represents a gene product. Better to annotate with GO:0016922 nuclear receptor binding and estrogen receptor as ‘has_input’.”
obsolete nuclear estrogen receptor binding label “obsolete nuclear estrogen receptor binding”

obsolete nuclear glucocorticoid receptor binding `http://purl.obolibrary.org/obo/GO_0035259`

Removed

obsolete nuclear glucocorticoid receptor binding never in taxon Archaea
obsolete nuclear glucocorticoid receptor binding never in taxon Bacteria
obsolete nuclear glucocorticoid receptor binding never in taxon Fungi
obsolete nuclear glucocorticoid receptor binding conformsTo binding.yaml
obsolete nuclear glucocorticoid receptor binding definition “Binding to a nuclear glucocorticoid receptor.”
- has cross-reference “GOC:bf”
obsolete nuclear glucocorticoid receptor binding label “nuclear glucocorticoid receptor binding”
obsolete nuclear glucocorticoid receptor binding EquivalentTo binding and (has primary input some glucocorticoid receptor)
obsolete nuclear glucocorticoid receptor binding SubClassOf nuclear receptor binding
obsolete nuclear glucocorticoid receptor binding SubClassOf not (in taxon some Archaea)
obsolete nuclear glucocorticoid receptor binding SubClassOf not (in taxon some Bacteria)
obsolete nuclear glucocorticoid receptor binding SubClassOf not (in taxon some Fungi)
obsolete nuclear glucocorticoid receptor binding SubClassOf has primary input some glucocorticoid receptor

Added

obsolete nuclear glucocorticoid receptor binding term tracker item “https://github.com/geneontology/go-ontology/issues/32475”^^anyURI
obsolete nuclear glucocorticoid receptor binding consider nuclear receptor binding
obsolete nuclear glucocorticoid receptor binding definition “OBSOLETE. Binding to a nuclear glucocorticoid receptor.”
- has cross-reference “GOC:bf”
obsolete nuclear glucocorticoid receptor binding deprecated true
obsolete nuclear glucocorticoid receptor binding comment “The reason for obsoletion is that this term represents a gene product. Better to annotate with GO:0016922 nuclear receptor binding and glucocorticoid receptor as ‘has_input’.”
obsolete nuclear glucocorticoid receptor binding label “obsolete nuclear glucocorticoid receptor binding”

obsolete nuclear mineralocorticoid receptor binding `http://purl.obolibrary.org/obo/GO_0031962`

Removed

obsolete nuclear mineralocorticoid receptor binding never in taxon Archaea
obsolete nuclear mineralocorticoid receptor binding never in taxon Bacteria
obsolete nuclear mineralocorticoid receptor binding never in taxon Fungi
obsolete nuclear mineralocorticoid receptor binding conformsTo binding.yaml
obsolete nuclear mineralocorticoid receptor binding definition “Binding to a nuclear mineralocorticoid receptor.”
- has cross-reference “GOC:mah”
- has cross-reference “PMID:12511169”
obsolete nuclear mineralocorticoid receptor binding label “nuclear mineralocorticoid receptor binding”
obsolete nuclear mineralocorticoid receptor binding EquivalentTo binding and (has primary input some mineralocorticoid receptor)
obsolete nuclear mineralocorticoid receptor binding SubClassOf nuclear receptor binding
obsolete nuclear mineralocorticoid receptor binding SubClassOf not (in taxon some Archaea)
obsolete nuclear mineralocorticoid receptor binding SubClassOf not (in taxon some Bacteria)
obsolete nuclear mineralocorticoid receptor binding SubClassOf not (in taxon some Fungi)
obsolete nuclear mineralocorticoid receptor binding SubClassOf has primary input some mineralocorticoid receptor

Added

obsolete nuclear mineralocorticoid receptor binding term tracker item “https://github.com/geneontology/go-ontology/issues/32475”^^anyURI
obsolete nuclear mineralocorticoid receptor binding consider nuclear receptor binding
obsolete nuclear mineralocorticoid receptor binding definition “OBSOLETE. Binding to a nuclear mineralocorticoid receptor.”
- has cross-reference “GOC:mah”
- has cross-reference “PMID:12511169”
obsolete nuclear mineralocorticoid receptor binding deprecated true
obsolete nuclear mineralocorticoid receptor binding comment “The reason for obsoletion is that this term represents a gene product. Better to annotate with GO:0016922 nuclear receptor binding and mineralocorticoid receptor as ‘has_input’.”
obsolete nuclear mineralocorticoid receptor binding label “obsolete nuclear mineralocorticoid receptor binding”

obsolete nuclear progesterone receptor binding `http://purl.obolibrary.org/obo/GO_0033142`

Removed

obsolete nuclear progesterone receptor binding never in taxon Archaea
obsolete nuclear progesterone receptor binding never in taxon Bacteria
obsolete nuclear progesterone receptor binding never in taxon Fungi
obsolete nuclear progesterone receptor binding conformsTo binding.yaml
obsolete nuclear progesterone receptor binding definition “Binding to a nuclear progesterone receptor.”
- has cross-reference “GOC:mah”
obsolete nuclear progesterone receptor binding label “nuclear progesterone receptor binding”
obsolete nuclear progesterone receptor binding EquivalentTo binding and (has primary input some progesterone receptor)
obsolete nuclear progesterone receptor binding SubClassOf nuclear receptor binding
obsolete nuclear progesterone receptor binding SubClassOf not (in taxon some Archaea)
obsolete nuclear progesterone receptor binding SubClassOf not (in taxon some Bacteria)
obsolete nuclear progesterone receptor binding SubClassOf not (in taxon some Fungi)
obsolete nuclear progesterone receptor binding SubClassOf has primary input some progesterone receptor

Added

obsolete nuclear progesterone receptor binding term tracker item “https://github.com/geneontology/go-ontology/issues/32475”^^anyURI
obsolete nuclear progesterone receptor binding consider nuclear receptor binding
obsolete nuclear progesterone receptor binding definition “OBSOLETE. Binding to a nuclear progesterone receptor.”
- has cross-reference “GOC:mah”
obsolete nuclear progesterone receptor binding deprecated true
obsolete nuclear progesterone receptor binding comment “The reason for obsoletion is that this term represents a gene product. Better to annotate with GO:0016922 nuclear receptor binding and progesterone receptor as ‘has_input’.”
obsolete nuclear progesterone receptor binding label “obsolete nuclear progesterone receptor binding”

obsolete nuclear retinoic acid receptor binding `http://purl.obolibrary.org/obo/GO_0042974`

Removed

obsolete nuclear retinoic acid receptor binding never in taxon Archaea
obsolete nuclear retinoic acid receptor binding never in taxon Bacteria
obsolete nuclear retinoic acid receptor binding never in taxon Fungi
obsolete nuclear retinoic acid receptor binding definition “Binding to a nuclear retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily.”
- has cross-reference “PMID:12476796”
- has cross-reference “GOC:jl”
obsolete nuclear retinoic acid receptor binding label “nuclear retinoic acid receptor binding”
obsolete nuclear retinoic acid receptor binding SubClassOf nuclear receptor binding
obsolete nuclear retinoic acid receptor binding SubClassOf not (in taxon some Archaea)
obsolete nuclear retinoic acid receptor binding SubClassOf not (in taxon some Bacteria)
obsolete nuclear retinoic acid receptor binding SubClassOf not (in taxon some Fungi)

Added

obsolete nuclear retinoic acid receptor binding term tracker item “https://github.com/geneontology/go-ontology/issues/32475”^^anyURI
obsolete nuclear retinoic acid receptor binding consider nuclear receptor binding
obsolete nuclear retinoic acid receptor binding definition “OBSOLETE. Binding to a nuclear retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily.”
- has cross-reference “PMID:12476796”
- has cross-reference “GOC:jl”
obsolete nuclear retinoic acid receptor binding deprecated true
obsolete nuclear retinoic acid receptor binding comment “The reason for obsoletion is that this term represents a gene product. Better to annotate with GO:0016922 nuclear receptor binding and retinoic acid receptor as ‘has_input’.”
obsolete nuclear retinoic acid receptor binding label “obsolete nuclear retinoic acid receptor binding”

obsolete nuclear retinoid X receptor binding `http://purl.obolibrary.org/obo/GO_0046965`

Removed

obsolete nuclear retinoid X receptor binding never in taxon Archaea
obsolete nuclear retinoid X receptor binding never in taxon Bacteria
obsolete nuclear retinoid X receptor binding never in taxon Fungi
obsolete nuclear retinoid X receptor binding definition “Binding to a nuclear retinoid X receptor.”
- has cross-reference “GOC:ai”
obsolete nuclear retinoid X receptor binding label “nuclear retinoid X receptor binding”
obsolete nuclear retinoid X receptor binding SubClassOf obsolete nuclear retinoic acid receptor binding
obsolete nuclear retinoid X receptor binding SubClassOf not (in taxon some Archaea)
obsolete nuclear retinoid X receptor binding SubClassOf not (in taxon some Bacteria)
obsolete nuclear retinoid X receptor binding SubClassOf not (in taxon some Fungi)

Added

obsolete nuclear retinoid X receptor binding term tracker item “https://github.com/geneontology/go-ontology/issues/32475”^^anyURI
obsolete nuclear retinoid X receptor binding consider nuclear receptor binding
obsolete nuclear retinoid X receptor binding definition “OBSOLETE. Binding to a nuclear retinoid X receptor.”
- has cross-reference “GOC:ai”
obsolete nuclear retinoid X receptor binding deprecated true
obsolete nuclear retinoid X receptor binding comment “The reason for obsoletion is that this term represents a gene product. Better to annotate with GO:0016922 nuclear receptor binding and retinoid X receptor as ‘has_input’.”
obsolete nuclear retinoid X receptor binding label “obsolete nuclear retinoid X receptor binding”

obsolete nuclear thyroid hormone receptor binding `http://purl.obolibrary.org/obo/GO_0046966`

Removed

obsolete nuclear thyroid hormone receptor binding never in taxon Archaea
obsolete nuclear thyroid hormone receptor binding never in taxon Bacteria
obsolete nuclear thyroid hormone receptor binding never in taxon Fungi
obsolete nuclear thyroid hormone receptor binding definition “Binding to a nuclear thyroid hormone receptor.”
- has cross-reference “GOC:ai”
obsolete nuclear thyroid hormone receptor binding label “nuclear thyroid hormone receptor binding”
obsolete nuclear thyroid hormone receptor binding SubClassOf nuclear receptor binding
obsolete nuclear thyroid hormone receptor binding SubClassOf not (in taxon some Archaea)
obsolete nuclear thyroid hormone receptor binding SubClassOf not (in taxon some Bacteria)
obsolete nuclear thyroid hormone receptor binding SubClassOf not (in taxon some Fungi)

Added

obsolete nuclear thyroid hormone receptor binding term tracker item “https://github.com/geneontology/go-ontology/issues/32475”^^anyURI
obsolete nuclear thyroid hormone receptor binding consider nuclear receptor binding
obsolete nuclear thyroid hormone receptor binding definition “OBSOLETE. Binding to a nuclear thyroid hormone receptor.”
- has cross-reference “GOC:ai”
obsolete nuclear thyroid hormone receptor binding deprecated true
obsolete nuclear thyroid hormone receptor binding comment “The reason for obsoletion is that this term represents a gene product. Better to annotate with GO:0016922 nuclear receptor binding and thyroid hormone receptor as ‘has_input’.”
obsolete nuclear thyroid hormone receptor binding label “obsolete nuclear thyroid hormone receptor binding”

obsolete nuclear vitamin D receptor binding `http://purl.obolibrary.org/obo/GO_0042809`

Removed

obsolete nuclear vitamin D receptor binding never in taxon Archaea
obsolete nuclear vitamin D receptor binding never in taxon Bacteria
obsolete nuclear vitamin D receptor binding never in taxon Fungi
obsolete nuclear vitamin D receptor binding conformsTo binding.yaml
obsolete nuclear vitamin D receptor binding definition “Binding to a nuclear vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes.”
- has cross-reference “PMID:12637589”
- has cross-reference “GOC:jl”
obsolete nuclear vitamin D receptor binding label “nuclear vitamin D receptor binding”
obsolete nuclear vitamin D receptor binding EquivalentTo binding and (has primary input some vitamin D3 receptor)
obsolete nuclear vitamin D receptor binding SubClassOf nuclear receptor binding
obsolete nuclear vitamin D receptor binding SubClassOf not (in taxon some Archaea)
obsolete nuclear vitamin D receptor binding SubClassOf not (in taxon some Bacteria)
obsolete nuclear vitamin D receptor binding SubClassOf not (in taxon some Fungi)
obsolete nuclear vitamin D receptor binding SubClassOf has primary input some vitamin D3 receptor

Added

obsolete nuclear vitamin D receptor binding term tracker item “https://github.com/geneontology/go-ontology/issues/32475”^^anyURI
obsolete nuclear vitamin D receptor binding consider nuclear receptor binding
obsolete nuclear vitamin D receptor binding definition “OBSOLETE. Binding to a nuclear vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes.”
- has cross-reference “PMID:12637589”
- has cross-reference “GOC:jl”
obsolete nuclear vitamin D receptor binding deprecated true
obsolete nuclear vitamin D receptor binding comment “The reason for obsoletion is that this term represents a gene product. Better to annotate with GO:0016922 nuclear receptor binding and vitamin D3 receptor as ‘has_input’.”
obsolete nuclear vitamin D receptor binding label “obsolete nuclear vitamin D receptor binding”

obsolete ocellus pigment granule organization `http://purl.obolibrary.org/obo/GO_0008058`

Removed

obsolete ocellus pigment granule organization definition “A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus.”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”
obsolete ocellus pigment granule organization label “ocellus pigment granule organization”
obsolete ocellus pigment granule organization SubClassOf pigment granule organization
obsolete ocellus pigment granule organization SubClassOf in taxon some cellular organisms

Added

obsolete ocellus pigment granule organization term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
obsolete ocellus pigment granule organization definition “OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus.”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”
obsolete ocellus pigment granule organization deprecated true
obsolete ocellus pigment granule organization comment “The reason for obsoletion is that this term was made in error.”
obsolete ocellus pigment granule organization label “obsolete ocellus pigment granule organization”

obsolete octadecene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900682`

Removed

obsolete octadecene biosynthetic process conformsTo biosynthetic_process.yaml

obsolete octadecene metabolic process `http://purl.obolibrary.org/obo/GO_1900681`

Removed

obsolete octadecene metabolic process conformsTo metabolic_process.yaml

obsolete palmitic acid catabolic process `http://purl.obolibrary.org/obo/GO_1900534`

Removed

obsolete palmitic acid catabolic process conformsTo catabolic_process.yaml

obsolete pentadecane metabolic process `http://purl.obolibrary.org/obo/GO_1900633`

Removed

obsolete pentadecane metabolic process conformsTo metabolic_process.yaml

obsolete pentaerythritol tetranitrate metabolic process `http://purl.obolibrary.org/obo/GO_0018954`

Removed

obsolete pentaerythritol tetranitrate metabolic process conformsTo metabolic_process.yaml

obsolete peptidyl-glutamate ADP-deribosylation `http://purl.obolibrary.org/obo/GO_0140291`

Removed

obsolete peptidyl-glutamate ADP-deribosylation definition “The removal of ADP-ribose from ADP-ribosylglutamate.”
- has cross-reference “PMID:23481255”
obsolete peptidyl-glutamate ADP-deribosylation label “peptidyl-glutamate ADP-deribosylation”
obsolete peptidyl-glutamate ADP-deribosylation SubClassOf protein de-ADP-ribosylation

Added

obsolete peptidyl-glutamate ADP-deribosylation term tracker item “https://github.com/geneontology/go-ontology/issues/32538”^^anyURI
obsolete peptidyl-glutamate ADP-deribosylation consider ADP-ribosylglutamate-[protein] hydrolase activity
obsolete peptidyl-glutamate ADP-deribosylation definition “OBSOLETE. The removal of ADP-ribose from ADP-ribosylglutamate.”
- has cross-reference “PMID:23481255”
obsolete peptidyl-glutamate ADP-deribosylation deprecated true
obsolete peptidyl-glutamate ADP-deribosylation comment “This term was obsoleted because it represents a molecular function.”
obsolete peptidyl-glutamate ADP-deribosylation label “obsolete peptidyl-glutamate ADP-deribosylation”

obsolete peptidyl-serine ADP-deribosylation `http://purl.obolibrary.org/obo/GO_0140290`

Removed

obsolete peptidyl-serine ADP-deribosylation definition “The removal of ADP-ribose from ADP-ribosylserine.”
- has cross-reference “PMID:28650317”
- has cross-reference “PMID:29234005”
obsolete peptidyl-serine ADP-deribosylation label “peptidyl-serine ADP-deribosylation”
obsolete peptidyl-serine ADP-deribosylation SubClassOf protein de-ADP-ribosylation

Added

obsolete peptidyl-serine ADP-deribosylation term tracker item “https://github.com/geneontology/go-ontology/issues/32538”^^anyURI
obsolete peptidyl-serine ADP-deribosylation consider ADP-ribosylserine-[protein] hydrolase activity
obsolete peptidyl-serine ADP-deribosylation definition “OBSOLETE. The removal of ADP-ribose from ADP-ribosylserine.”
- has cross-reference “PMID:28650317”
- has cross-reference “PMID:29234005”
obsolete peptidyl-serine ADP-deribosylation deprecated true
obsolete peptidyl-serine ADP-deribosylation comment “This term was obsoleted because it represents a molecular function.”
obsolete peptidyl-serine ADP-deribosylation label “obsolete peptidyl-serine ADP-deribosylation”

obsolete phagolysosome vesicle membrane `http://purl.obolibrary.org/obo/GO_0106175`

Removed

obsolete phagolysosome vesicle membrane never in taxon Fungi
obsolete phagolysosome vesicle membrane definition “The lipid bylayer surrounding a phagolysosome.”
- has cross-reference “GOC:pde”
- has cross-reference “PMID:29471269”
obsolete phagolysosome vesicle membrane label “phagolysosome vesicle membrane”
obsolete phagolysosome vesicle membrane SubClassOf cytoplasmic vesicle membrane
obsolete phagolysosome vesicle membrane SubClassOf not (in taxon some Fungi)
obsolete phagolysosome vesicle membrane SubClassOf part of some phagolysosome
obsolete phagolysosome vesicle membrane SubClassOf in taxon some Eukaryota

Added

obsolete phagolysosome vesicle membrane term tracker item “https://github.com/geneontology/go-ontology/issues/32571”^^anyURI
obsolete phagolysosome vesicle membrane term replaced by phagolysosome membrane
obsolete phagolysosome vesicle membrane definition “OBSOLETE. The lipid bilayer surrounding a phagolysosome.”
- has cross-reference “GOC:pde”
- has cross-reference “PMID:29471269”
obsolete phagolysosome vesicle membrane deprecated true
obsolete phagolysosome vesicle membrane comment “This term was obsoleted because it was created by error. It is identical to phagolysosome membrane ; GO:0061474.”
obsolete phagolysosome vesicle membrane label “obsolete phagolysosome vesicle membrane”

obsolete phagophore assembly site membrane `http://purl.obolibrary.org/obo/GO_0034045`

Removed

obsolete phagophore assembly site membrane definition “A cellular membrane associated with the phagophore assembly site.”
- has cross-reference “PMID:16874040”
- has cross-reference “PMID:17382324”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:rph”
obsolete phagophore assembly site membrane label “phagophore assembly site membrane”
obsolete phagophore assembly site membrane EquivalentTo membrane and (bounding layer of some phagophore assembly site)
obsolete phagophore assembly site membrane SubClassOf membrane
obsolete phagophore assembly site membrane SubClassOf part of some phagophore assembly site
obsolete phagophore assembly site membrane SubClassOf bounding layer of some phagophore assembly site
obsolete phagophore assembly site membrane SubClassOf in taxon some cellular organisms

Added

obsolete phagophore assembly site membrane term tracker item “https://github.com/geneontology/go-ontology/issues/29437”^^anyURI
obsolete phagophore assembly site membrane term replaced by phagophore membrane
obsolete phagophore assembly site membrane definition “OBSOLETE. A cellular membrane associated with the phagophore assembly site.”
- has cross-reference “PMID:16874040”
- has cross-reference “PMID:17382324”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:rph”
obsolete phagophore assembly site membrane deprecated true
obsolete phagophore assembly site membrane comment “This term was obsoleted because the phagophore assembly site (PAS) is not itself a membrane-bounded compartment, and the class had become a catch-all for membranes at, or associated with, the site of phagophore biogenesis. Annotations should be moved to phagophore membrane (GO:7770114), which captures the membrane of the nascent phagophore, or to another more appropriate term (e.g. GO:0000407 phagophore assembly site, GO:0061908 phagophore) depending on the evidence.”
obsolete phagophore assembly site membrane label “obsolete phagophore assembly site membrane”

obsolete phenylalanyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006432`

Removed

obsolete phenylalanyl-tRNA aminoacylation definition “The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2’-OH group of a phenylalanine-accepting tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete phenylalanyl-tRNA aminoacylation label “phenylalanyl-tRNA aminoacylation”
obsolete phenylalanyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete phenylalanyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete phenylalanyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete phenylalanyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete phenylalanyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2’-OH group of a phenylalanine-accepting tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete phenylalanyl-tRNA aminoacylation deprecated true
obsolete phenylalanyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004826 phenylalanine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete phenylalanyl-tRNA aminoacylation label “obsolete phenylalanyl-tRNA aminoacylation”

obsolete phosphinothricin catabolic process `http://purl.obolibrary.org/obo/GO_1901765`

Removed

obsolete phosphinothricin catabolic process conformsTo catabolic_process.yaml

obsolete phosphinothricin metabolic process `http://purl.obolibrary.org/obo/GO_1901764`

Removed

obsolete phosphinothricin metabolic process conformsTo metabolic_process.yaml

obsolete poly(hydroxyalkanoate) metabolic process `http://purl.obolibrary.org/obo/GO_1901440`

Removed

obsolete poly(hydroxyalkanoate) metabolic process conformsTo metabolic_process.yaml

obsolete positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900943`

Removed

obsolete positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of 17-methylnonadec-1-ene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900958`

Removed

obsolete positive regulation of 17-methylnonadec-1-ene biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of 18-methylnonadec-1-ene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900952`

Removed

obsolete positive regulation of 18-methylnonadec-1-ene biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of cordyol C biosynthetic process `http://purl.obolibrary.org/obo/GO_1900863`

Removed

obsolete positive regulation of cordyol C biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of diorcinol biosynthetic process `http://purl.obolibrary.org/obo/GO_1900657`

Removed

obsolete positive regulation of diorcinol biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape `http://purl.obolibrary.org/obo/GO_0061161`

Removed

obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape definition “Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell.”
- has cross-reference “GOC:dph”
- has cross-reference “GOC:vw”
obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape label “positive regulation of establishment of bipolar cell polarity regulating cell shape”
obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of establishment of bipolar cell polarity regulating cell shape
obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf positive regulation of establishment of bipolar cell polarity
obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape
obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

Added

obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI
obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity
obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell.”
- has cross-reference “GOC:dph”
- has cross-reference “GOC:vw”
obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape deprecated true
obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”
obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape label “obsolete positive regulation of establishment of bipolar cell polarity regulating cell shape”

obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape `http://purl.obolibrary.org/obo/GO_2000247`

Removed

obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape conformsTo positive_regulation.yaml
obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape definition “Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.”
- has cross-reference “GOC:obol”
obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape label “positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape”
obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape EquivalentTo biological regulation and (positively regulates some obsolete establishment or maintenance of bipolar cell polarity regulating cell shape)
obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape
obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf positive regulation of establishment or maintenance of cell polarity regulating cell shape
obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms
obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf positively regulates some obsolete establishment or maintenance of bipolar cell polarity regulating cell shape

Added

obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI
obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity
obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.”
- has cross-reference “GOC:obol”
obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape deprecated true
obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that these terms were added in error.”
obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape label “obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape”

obsolete positive regulation of glycolytic process through fructose-6-phosphate `http://purl.obolibrary.org/obo/GO_1904540`

Removed

obsolete positive regulation of glycolytic process through fructose-6-phosphate definition “Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
- has cross-reference “GOC:TermGenie”
obsolete positive regulation of glycolytic process through fructose-6-phosphate label “positive regulation of glycolytic process through fructose-6-phosphate”
obsolete positive regulation of glycolytic process through fructose-6-phosphate EquivalentTo biological regulation and (positively regulates some obsolete glycolytic process through fructose-6-phosphate)
obsolete positive regulation of glycolytic process through fructose-6-phosphate SubClassOf positive regulation of glycolysis
obsolete positive regulation of glycolytic process through fructose-6-phosphate SubClassOf positively regulates some obsolete glycolytic process through fructose-6-phosphate

Added

obsolete positive regulation of glycolytic process through fructose-6-phosphate term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete positive regulation of glycolytic process through fructose-6-phosphate term replaced by positive regulation of glycolysis
obsolete positive regulation of glycolytic process through fructose-6-phosphate definition “OBSOLETE. Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “GOC:dph”
- has cross-reference “ISBN:0201090910”
- has cross-reference “ISBN:0879010479”
- has cross-reference “GOC:TermGenie”
obsolete positive regulation of glycolytic process through fructose-6-phosphate deprecated true
obsolete positive regulation of glycolytic process through fructose-6-phosphate comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete positive regulation of glycolytic process through fructose-6-phosphate label “obsolete positive regulation of glycolytic process through fructose-6-phosphate”

obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape `http://purl.obolibrary.org/obo/GO_0061361`

Removed

obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape definition “Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.”
- has cross-reference “GOC:dph”
obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape label “positive regulation of maintenance of bipolar cell polarity regulating cell shape”
obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of maintenance of bipolar cell polarity regulating cell shape
obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape
obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms
obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf positively regulates some obsolete maintenance of bipolar cell polarity regulating cell shape

Added

obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI
obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity
obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.”
- has cross-reference “GOC:dph”
obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape deprecated true
obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”
obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape label “obsolete positive regulation of maintenance of bipolar cell polarity regulating cell shape”

obsolete positive regulation of nonadec-1-ene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900937`

Removed

obsolete positive regulation of nonadec-1-ene biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of octadecene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900916`

Removed

obsolete positive regulation of octadecene biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of palmitic acid catabolic process `http://purl.obolibrary.org/obo/GO_0106395`

Removed

obsolete positive regulation of palmitic acid catabolic process conformsTo positive_regulation.yaml

obsolete positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway `http://purl.obolibrary.org/obo/GO_1900740`

Removed

obsolete positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway consider obsolete positive regulation of protein localization to mitochondrion

obsolete positive regulation of protein localization to mitochondrion `http://purl.obolibrary.org/obo/GO_1903749`

Removed

obsolete positive regulation of protein localization to mitochondrion term tracker item “https://github.com/geneontology/go-ontology/issues/30349”^^anyURI
obsolete positive regulation of protein localization to mitochondrion conformsTo positive_regulation.yaml
obsolete positive regulation of protein localization to mitochondrion definition “Any process that activates or increases the frequency, rate or extent of protein localization to mitochondrion.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “PMID:16857185”
- has cross-reference “GOC:TermGenie”
obsolete positive regulation of protein localization to mitochondrion label “positive regulation of protein localization to mitochondrion”
obsolete positive regulation of protein localization to mitochondrion EquivalentTo biological regulation and (positively regulates some protein localization to mitochondrion)
obsolete positive regulation of protein localization to mitochondrion SubClassOf obsolete regulation of protein localization to mitochondrion
obsolete positive regulation of protein localization to mitochondrion SubClassOf positive regulation of protein localization
obsolete positive regulation of protein localization to mitochondrion SubClassOf positively regulates some protein localization to mitochondrion

Added

obsolete positive regulation of protein localization to mitochondrion term tracker item “https://github.com/geneontology/go-ontology/issues/32107”^^anyURI
obsolete positive regulation of protein localization to mitochondrion definition “OBSOLETE. Any process that activates or increases the frequency, rate or extent of protein localization to mitochondrion.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “PMID:16857185”
- has cross-reference “GOC:TermGenie”
obsolete positive regulation of protein localization to mitochondrion deprecated true
obsolete positive regulation of protein localization to mitochondrion comment “The reason for obsoletion is that this term represents a phenotype and was added in error. Consider annotating to positive regulation of the specific process being regulated (e.g. positive regulation of mitophagy) or to a specific mitochondrial protein import pathway; if the underlying evidence is a readout or a phenotype, or the mechanism is unclear, consider removal rather than re-annotation.”
obsolete positive regulation of protein localization to mitochondrion label “obsolete positive regulation of protein localization to mitochondrion”

obsolete positive regulation of protein targeting to mitochondrion `http://purl.obolibrary.org/obo/GO_1903955`

Removed

obsolete positive regulation of protein targeting to mitochondrion term replaced by obsolete positive regulation of protein localization to mitochondrion

obsolete positive regulation of retrograde protein transport, ER to cytosol `http://purl.obolibrary.org/obo/GO_1904154`

Removed

obsolete positive regulation of retrograde protein transport, ER to cytosol definition “Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “GOC:PARL”
- has cross-reference “PMID:18555783”
- has cross-reference “GOC:bf”
- has cross-reference “GOC:TermGenie”
obsolete positive regulation of retrograde protein transport, ER to cytosol label “positive regulation of retrograde protein transport, ER to cytosol”
obsolete positive regulation of retrograde protein transport, ER to cytosol EquivalentTo biological regulation and (positively regulates some retrograde protein transport, ER to cytosol)
obsolete positive regulation of retrograde protein transport, ER to cytosol SubClassOf positive regulation of protein transport
obsolete positive regulation of retrograde protein transport, ER to cytosol SubClassOf obsolete regulation of retrograde protein transport, ER to cytosol
obsolete positive regulation of retrograde protein transport, ER to cytosol SubClassOf positively regulates some retrograde protein transport, ER to cytosol

Added

obsolete positive regulation of retrograde protein transport, ER to cytosol term tracker item “https://github.com/geneontology/go-ontology/issues/32525”^^anyURI
obsolete positive regulation of retrograde protein transport, ER to cytosol term replaced by positive regulation of ERAD pathway
obsolete positive regulation of retrograde protein transport, ER to cytosol definition “OBSOLETE. Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “GOC:PARL”
- has cross-reference “PMID:18555783”
- has cross-reference “GOC:bf”
- has cross-reference “GOC:TermGenie”
obsolete positive regulation of retrograde protein transport, ER to cytosol deprecated true
obsolete positive regulation of retrograde protein transport, ER to cytosol comment “The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent, the data from the paper for which the term was requested can be accurately described using reguation of ERAD pathway terms, and this term was added in error.”
obsolete positive regulation of retrograde protein transport, ER to cytosol label “obsolete positive regulation of retrograde protein transport, ER to cytosol”

obsolete positive regulation of tatiopterin biosynthetic process `http://purl.obolibrary.org/obo/GO_1900976`

Removed

obsolete positive regulation of tatiopterin biosynthetic process conformsTo positive_regulation.yaml

obsolete positive regulation of transcription from RNA polymerase II promoter by galactose `http://purl.obolibrary.org/obo/GO_0000435`

Removed

obsolete positive regulation of transcription from RNA polymerase II promoter by galactose definition “Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter.”
- has cross-reference “GOC:krc”
obsolete positive regulation of transcription from RNA polymerase II promoter by galactose label “positive regulation of transcription from RNA polymerase II promoter by galactose”
obsolete positive regulation of transcription from RNA polymerase II promoter by galactose SubClassOf positive regulation of transcription by galactose
obsolete positive regulation of transcription from RNA polymerase II promoter by galactose SubClassOf obsolete regulation of transcription from RNA polymerase II promoter by galactose
obsolete positive regulation of transcription from RNA polymerase II promoter by galactose SubClassOf obsolete carbon catabolite activation of transcription from RNA polymerase II promoter

Added

obsolete positive regulation of transcription from RNA polymerase II promoter by galactose term tracker item “https://github.com/geneontology/go-ontology/issues/21442”^^anyURI
obsolete positive regulation of transcription from RNA polymerase II promoter by galactose consider positive regulation of transcription by RNA polymerase II
obsolete positive regulation of transcription from RNA polymerase II promoter by galactose definition “OBSOLETE. Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter.”
- has cross-reference “GOC:krc”
obsolete positive regulation of transcription from RNA polymerase II promoter by galactose deprecated true
obsolete positive regulation of transcription from RNA polymerase II promoter by galactose comment “The reason for obsoletion is that these terms represent GO-CAM models.”
obsolete positive regulation of transcription from RNA polymerase II promoter by galactose label “obsolete positive regulation of transcription from RNA polymerase II promoter by galactose”

obsolete positive regulation of transcription from RNA polymerase II promoter by glucose `http://purl.obolibrary.org/obo/GO_0000432`

Removed

obsolete positive regulation of transcription from RNA polymerase II promoter by glucose definition “Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter.”
- has cross-reference “GOC:krc”
obsolete positive regulation of transcription from RNA polymerase II promoter by glucose label “positive regulation of transcription from RNA polymerase II promoter by glucose”
obsolete positive regulation of transcription from RNA polymerase II promoter by glucose SubClassOf obsolete regulation of transcription from RNA polymerase II promoter by glucose
obsolete positive regulation of transcription from RNA polymerase II promoter by glucose SubClassOf obsolete carbon catabolite activation of transcription from RNA polymerase II promoter
obsolete positive regulation of transcription from RNA polymerase II promoter by glucose SubClassOf positive regulation of transcription by glucose

Added

obsolete positive regulation of transcription from RNA polymerase II promoter by glucose term tracker item “https://github.com/geneontology/go-ontology/issues/21442”^^anyURI
obsolete positive regulation of transcription from RNA polymerase II promoter by glucose consider positive regulation of transcription by RNA polymerase II
obsolete positive regulation of transcription from RNA polymerase II promoter by glucose definition “OBSOLETE. Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter.”
- has cross-reference “GOC:krc”
obsolete positive regulation of transcription from RNA polymerase II promoter by glucose deprecated true
obsolete positive regulation of transcription from RNA polymerase II promoter by glucose comment “The reason for obsoletion is that these terms represent GO-CAM models.”
obsolete positive regulation of transcription from RNA polymerase II promoter by glucose label “obsolete positive regulation of transcription from RNA polymerase II promoter by glucose”

obsolete positive regulation of transcription from RNA polymerase II promoter by oleic acid `http://purl.obolibrary.org/obo/GO_0061429`

Removed

obsolete positive regulation of transcription from RNA polymerase II promoter by oleic acid definition “Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.”
- has cross-reference “PMID:20395639”
- has cross-reference “GOC:dph”
obsolete positive regulation of transcription from RNA polymerase II promoter by oleic acid label “positive regulation of transcription from RNA polymerase II promoter by oleic acid”
obsolete positive regulation of transcription from RNA polymerase II promoter by oleic acid SubClassOf obsolete carbon catabolite activation of transcription from RNA polymerase II promoter

Added

obsolete positive regulation of transcription from RNA polymerase II promoter by oleic acid term tracker item “https://github.com/geneontology/go-ontology/issues/21442”^^anyURI
obsolete positive regulation of transcription from RNA polymerase II promoter by oleic acid consider positive regulation of transcription by RNA polymerase II
obsolete positive regulation of transcription from RNA polymerase II promoter by oleic acid definition “OBSOLETE. Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.”
- has cross-reference “PMID:20395639”
- has cross-reference “GOC:dph”
obsolete positive regulation of transcription from RNA polymerase II promoter by oleic acid deprecated true
obsolete positive regulation of transcription from RNA polymerase II promoter by oleic acid comment “The reason for obsoletion is that these terms represent GO-CAM models.”
obsolete positive regulation of transcription from RNA polymerase II promoter by oleic acid label “obsolete positive regulation of transcription from RNA polymerase II promoter by oleic acid”

obsolete prolyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006433`

Removed

obsolete prolyl-tRNA aminoacylation definition “The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. The prolyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of a methionine-accetping tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “ISBN:0716730510”
obsolete prolyl-tRNA aminoacylation label “prolyl-tRNA aminoacylation”
obsolete prolyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete prolyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete prolyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete prolyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete prolyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. The prolyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of a methionine-accetping tRNA.”
- has cross-reference “GOC:mah”
- has cross-reference “ISBN:0716730510”
obsolete prolyl-tRNA aminoacylation deprecated true
obsolete prolyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004827 proline-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete prolyl-tRNA aminoacylation label “obsolete prolyl-tRNA aminoacylation”

obsolete protein auto-ADP-ribosylation `http://purl.obolibrary.org/obo/GO_0070213`

Removed

obsolete protein auto-ADP-ribosylation definition “The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.”
- has cross-reference “GOC:rl”
- has cross-reference “GOC:BHF”
obsolete protein auto-ADP-ribosylation label “protein auto-ADP-ribosylation”
obsolete protein auto-ADP-ribosylation SubClassOf post-translational protein modification

Added

obsolete protein auto-ADP-ribosylation term tracker item “https://github.com/geneontology/go-ontology/issues/32538”^^anyURI
obsolete protein auto-ADP-ribosylation consider NAD+ poly-ADP-ribosyltransferase activity
obsolete protein auto-ADP-ribosylation consider NAD+-protein mono-ADP-ribosyltransferase activity
obsolete protein auto-ADP-ribosylation definition “OBSOLETE. The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.”
- has cross-reference “GOC:rl”
- has cross-reference “GOC:BHF”
obsolete protein auto-ADP-ribosylation deprecated true
obsolete protein auto-ADP-ribosylation comment “This term was obsoleted because it represents a molecular function.”
obsolete protein auto-ADP-ribosylation label “obsolete protein auto-ADP-ribosylation”

obsolete protein depalmitoylation `http://purl.obolibrary.org/obo/GO_0002084`

Removed

obsolete protein depalmitoylation in_subset gocheck_obsoletion_candidate
obsolete protein depalmitoylation definition “The removal of palymitoyl groups from a lipoprotein.”
- has cross-reference “GOC:hjd”
obsolete protein depalmitoylation label “protein depalmitoylation”
obsolete protein depalmitoylation SubClassOf protein deacylation
obsolete protein depalmitoylation SubClassOf lipoprotein catabolic process
obsolete protein depalmitoylation SubClassOf obsolete macromolecule depalmitoylation

Added

obsolete protein depalmitoylation term tracker item “https://github.com/geneontology/go-ontology/issues/32290”^^anyURI
obsolete protein depalmitoylation consider palmitoyl-(protein) hydrolase activity
obsolete protein depalmitoylation definition “OBSOLETE. The removal of palymitoyl groups from a lipoprotein.”
- has cross-reference “GOC:hjd”
obsolete protein depalmitoylation deprecated true
obsolete protein depalmitoylation comment “The reason for obsoletion is that this term represents a molecular function, not a biological process. Consider instead annotating to the molecular function ‘palmitoyl-(protein) hydrolase activity’ (GO:0008474).”
obsolete protein depalmitoylation label “obsolete protein depalmitoylation”

obsolete protein localization to cytoplasmic stress granule `http://purl.obolibrary.org/obo/GO_1903608`

Removed

obsolete protein localization to cytoplasmic stress granule definition “A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule.”
- has cross-reference “PMID:24755092”
- has cross-reference “GO_REF:0000087”
- has cross-reference “GOC:TermGenie”
obsolete protein localization to cytoplasmic stress granule label “protein localization to cytoplasmic stress granule”
obsolete protein localization to cytoplasmic stress granule EquivalentTo intracellular protein localization and (has target end location some cytoplasmic stress granule)
obsolete protein localization to cytoplasmic stress granule SubClassOf protein localization to organelle
obsolete protein localization to cytoplasmic stress granule SubClassOf has target end location some cytoplasmic stress granule

Added

obsolete protein localization to cytoplasmic stress granule term tracker item “https://github.com/geneontology/go-ontology/issues/32318”^^anyURI
obsolete protein localization to cytoplasmic stress granule definition “OBSOLETE. A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule.”
- has cross-reference “PMID:24755092”
- has cross-reference “GO_REF:0000087”
- has cross-reference “GOC:TermGenie”
obsolete protein localization to cytoplasmic stress granule deprecated true
obsolete protein localization to cytoplasmic stress granule comment “The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent. In practice it was applied to proteins observed in stress granules, that is, to a co-localization readout rather than to a process that localizes a protein there. Annotations to this term have been reviewed and removed; see https://github.com/geneontology/go-annotation/issues/6484.”
obsolete protein localization to cytoplasmic stress granule label “obsolete protein localization to cytoplasmic stress granule”

obsolete protein mono-ADP-ribosylation `http://purl.obolibrary.org/obo/GO_0140289`

Removed

obsolete protein mono-ADP-ribosylation consider NAD+ poly-ADP-ribosyltransferase activity

Added

obsolete protein mono-ADP-ribosylation term tracker item “https://github.com/geneontology/go-ontology/issues/32538”^^anyURI
obsolete protein mono-ADP-ribosylation consider NAD+-protein mono-ADP-ribosyltransferase activity

obsolete protein poly-ADP-ribosylation `http://purl.obolibrary.org/obo/GO_0070212`

Removed

obsolete protein poly-ADP-ribosylation definition “The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.”
- has cross-reference “GOC:rl”
- has cross-reference “GOC:mah”
- has cross-reference “PMID:25043379”
- has cross-reference “GOC:BHF”
obsolete protein poly-ADP-ribosylation label “protein poly-ADP-ribosylation”
obsolete protein poly-ADP-ribosylation SubClassOf post-translational protein modification

Added

obsolete protein poly-ADP-ribosylation term tracker item “https://github.com/geneontology/go-ontology/issues/32538”^^anyURI
obsolete protein poly-ADP-ribosylation consider NAD+ poly-ADP-ribosyltransferase activity
obsolete protein poly-ADP-ribosylation definition “OBSOLETE. The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.”
- has cross-reference “GOC:rl”
- has cross-reference “GOC:mah”
- has cross-reference “PMID:25043379”
- has cross-reference “GOC:BHF”
obsolete protein poly-ADP-ribosylation deprecated true
obsolete protein poly-ADP-ribosylation comment “This term was obsoleted because it represents a molecular function.”
obsolete protein poly-ADP-ribosylation label “obsolete protein poly-ADP-ribosylation”

obsolete regulation of (Z)-nonadeca-1,14-diene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900941`

Removed

obsolete regulation of 17-methylnonadec-1-ene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900956`

Removed

obsolete regulation of 18-methylnonadec-1-ene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900950`

Removed

obsolete regulation of cordyol C biosynthetic process `http://purl.obolibrary.org/obo/GO_1900861`

Removed

obsolete regulation of diorcinol biosynthetic process `http://purl.obolibrary.org/obo/GO_1900655`

Removed

obsolete regulation of establishment of bipolar cell polarity regulating cell shape `http://purl.obolibrary.org/obo/GO_0061160`

Removed

obsolete regulation of establishment of bipolar cell polarity regulating cell shape definition “Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell.”
- has cross-reference “GOC:dph”
- has cross-reference “GOC:vw”
obsolete regulation of establishment of bipolar cell polarity regulating cell shape label “regulation of establishment of bipolar cell polarity regulating cell shape”
obsolete regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf regulation of establishment of bipolar cell polarity
obsolete regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape
obsolete regulation of establishment of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms

Added

obsolete regulation of establishment of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI
obsolete regulation of establishment of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity
obsolete regulation of establishment of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell.”
- has cross-reference “GOC:dph”
- has cross-reference “GOC:vw”
obsolete regulation of establishment of bipolar cell polarity regulating cell shape deprecated true
obsolete regulation of establishment of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”
obsolete regulation of establishment of bipolar cell polarity regulating cell shape label “obsolete regulation of establishment of bipolar cell polarity regulating cell shape”

obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape `http://purl.obolibrary.org/obo/GO_2000100`

Removed

obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape conformsTo regulation.yaml
obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape conformsTo regulation_by.yaml
obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape definition “Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.”
- has cross-reference “GOC:obol”
obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape label “regulation of establishment or maintenance of bipolar cell polarity regulating cell shape”
obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape EquivalentTo biological regulation and (regulates some obsolete establishment or maintenance of bipolar cell polarity regulating cell shape)
obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf regulation of establishment or maintenance of bipolar cell polarity
obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf regulation of establishment or maintenance of cell polarity regulating cell shape
obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms
obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape SubClassOf regulates some obsolete establishment or maintenance of bipolar cell polarity regulating cell shape

Added

obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI
obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity
obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.”
- has cross-reference “GOC:obol”
obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape deprecated true
obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”
obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape label “obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape”

obsolete regulation of isoprene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900947`

Removed

obsolete regulation of maintenance of bipolar cell polarity regulating cell shape `http://purl.obolibrary.org/obo/GO_2000115`

Removed

obsolete regulation of maintenance of bipolar cell polarity regulating cell shape conformsTo regulation.yaml
obsolete regulation of maintenance of bipolar cell polarity regulating cell shape conformsTo regulation_by.yaml
obsolete regulation of maintenance of bipolar cell polarity regulating cell shape definition “Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape.”
- has cross-reference “GOC:obol”
obsolete regulation of maintenance of bipolar cell polarity regulating cell shape label “regulation of maintenance of bipolar cell polarity regulating cell shape”
obsolete regulation of maintenance of bipolar cell polarity regulating cell shape EquivalentTo biological regulation and (regulates some obsolete maintenance of bipolar cell polarity regulating cell shape)
obsolete regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf obsolete regulation of establishment or maintenance of bipolar cell polarity regulating cell shape
obsolete regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf in taxon some cellular organisms
obsolete regulation of maintenance of bipolar cell polarity regulating cell shape SubClassOf regulates some obsolete maintenance of bipolar cell polarity regulating cell shape

Added

obsolete regulation of maintenance of bipolar cell polarity regulating cell shape term tracker item “https://github.com/geneontology/go-ontology/issues/21217”^^anyURI
obsolete regulation of maintenance of bipolar cell polarity regulating cell shape term replaced by establishment or maintenance of bipolar cell polarity
obsolete regulation of maintenance of bipolar cell polarity regulating cell shape definition “OBSOLETE. Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape.”
- has cross-reference “GOC:obol”
obsolete regulation of maintenance of bipolar cell polarity regulating cell shape deprecated true
obsolete regulation of maintenance of bipolar cell polarity regulating cell shape comment “The reason for obsoletion is that this term was made in error.”
obsolete regulation of maintenance of bipolar cell polarity regulating cell shape label “obsolete regulation of maintenance of bipolar cell polarity regulating cell shape”

obsolete regulation of nonadec-1-ene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900935`

Removed

obsolete regulation of octadecene biosynthetic process `http://purl.obolibrary.org/obo/GO_1900914`

Removed

obsolete regulation of palmitic acid catabolic process `http://purl.obolibrary.org/obo/GO_0106393`

Removed

obsolete regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway `http://purl.obolibrary.org/obo/GO_1900739`

Removed

obsolete regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway consider obsolete regulation of protein localization to mitochondrion

obsolete regulation of protein localization to mitochondrion `http://purl.obolibrary.org/obo/GO_1903747`

Removed

obsolete regulation of protein localization to mitochondrion term tracker item “https://github.com/geneontology/go-ontology/issues/30349”^^anyURI
obsolete regulation of protein localization to mitochondrion conformsTo regulation.yaml
obsolete regulation of protein localization to mitochondrion conformsTo regulation_by.yaml
obsolete regulation of protein localization to mitochondrion definition “Any process that modulates the frequency, rate or extent of protein localization to mitochondrion.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “PMID:16857185”
- has cross-reference “GOC:TermGenie”
obsolete regulation of protein localization to mitochondrion label “regulation of protein localization to mitochondrion”
obsolete regulation of protein localization to mitochondrion EquivalentTo biological regulation and (regulates some protein localization to mitochondrion)
obsolete regulation of protein localization to mitochondrion SubClassOf regulation of protein localization
obsolete regulation of protein localization to mitochondrion SubClassOf regulates some protein localization to mitochondrion

Added

obsolete regulation of protein localization to mitochondrion term tracker item “https://github.com/geneontology/go-ontology/issues/32107”^^anyURI
obsolete regulation of protein localization to mitochondrion definition “OBSOLETE. Any process that modulates the frequency, rate or extent of protein localization to mitochondrion.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “PMID:16857185”
- has cross-reference “GOC:TermGenie”
obsolete regulation of protein localization to mitochondrion deprecated true
obsolete regulation of protein localization to mitochondrion comment “The reason for obsoletion is that this term represents a phenotype and was added in error. Consider annotating to regulation of the specific process being regulated (e.g. regulation of mitophagy) or to a specific mitochondrial protein import pathway; if the underlying evidence is a readout or a phenotype, or the mechanism is unclear, consider removal rather than re-annotation.”
obsolete regulation of protein localization to mitochondrion label “obsolete regulation of protein localization to mitochondrion”

obsolete regulation of protein processing involved in protein targeting to mitochondrion `http://purl.obolibrary.org/obo/GO_1903216`

Removed

obsolete regulation of protein processing involved in protein targeting to mitochondrion term replaced by obsolete regulation of protein localization to mitochondrion

obsolete regulation of protein targeting to mitochondrion `http://purl.obolibrary.org/obo/GO_1903214`

Removed

obsolete regulation of protein targeting to mitochondrion term replaced by obsolete regulation of protein localization to mitochondrion

obsolete regulation of retrograde protein transport, ER to cytosol `http://purl.obolibrary.org/obo/GO_1904152`

Removed

obsolete regulation of retrograde protein transport, ER to cytosol definition “Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “GOC:PARL”
- has cross-reference “PMID:18555783”
- has cross-reference “GOC:bf”
- has cross-reference “GOC:TermGenie”
obsolete regulation of retrograde protein transport, ER to cytosol label “regulation of retrograde protein transport, ER to cytosol”
obsolete regulation of retrograde protein transport, ER to cytosol EquivalentTo biological regulation and (regulates some retrograde protein transport, ER to cytosol)
obsolete regulation of retrograde protein transport, ER to cytosol SubClassOf regulation of protein transport
obsolete regulation of retrograde protein transport, ER to cytosol SubClassOf regulates some retrograde protein transport, ER to cytosol

Added

obsolete regulation of retrograde protein transport, ER to cytosol term tracker item “https://github.com/geneontology/go-ontology/issues/32525”^^anyURI
obsolete regulation of retrograde protein transport, ER to cytosol term replaced by ERAD quality control pathway
obsolete regulation of retrograde protein transport, ER to cytosol definition “OBSOLETE. Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol.”
- has cross-reference “GO_REF:0000058”
- has cross-reference “GOC:PARL”
- has cross-reference “PMID:18555783”
- has cross-reference “GOC:bf”
- has cross-reference “GOC:TermGenie”
obsolete regulation of retrograde protein transport, ER to cytosol deprecated true
obsolete regulation of retrograde protein transport, ER to cytosol comment “The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent, the data from the paper for which the term was requested can be accurately described using reguation of ERAD pathway terms, and this term was added in error.”
obsolete regulation of retrograde protein transport, ER to cytosol label “obsolete regulation of retrograde protein transport, ER to cytosol”

obsolete regulation of tatiopterin biosynthetic process `http://purl.obolibrary.org/obo/GO_1900974`

Removed

obsolete regulation of transcription from RNA polymerase II promoter by galactose `http://purl.obolibrary.org/obo/GO_0000431`

Removed

obsolete regulation of transcription from RNA polymerase II promoter by galactose definition “Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.”
- has cross-reference “GOC:krc”
obsolete regulation of transcription from RNA polymerase II promoter by galactose label “regulation of transcription from RNA polymerase II promoter by galactose”
obsolete regulation of transcription from RNA polymerase II promoter by galactose SubClassOf regulation of transcription by galactose
obsolete regulation of transcription from RNA polymerase II promoter by galactose SubClassOf obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter

Added

obsolete regulation of transcription from RNA polymerase II promoter by galactose term tracker item “https://github.com/geneontology/go-ontology/issues/21442”^^anyURI
obsolete regulation of transcription from RNA polymerase II promoter by galactose consider regulation of transcription by RNA polymerase II
obsolete regulation of transcription from RNA polymerase II promoter by galactose definition “OBSOLETE. Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.”
- has cross-reference “GOC:krc”
obsolete regulation of transcription from RNA polymerase II promoter by galactose deprecated true
obsolete regulation of transcription from RNA polymerase II promoter by galactose comment “The reason for obsoletion is that these terms represent GO-CAM models.”
obsolete regulation of transcription from RNA polymerase II promoter by galactose label “obsolete regulation of transcription from RNA polymerase II promoter by galactose”

obsolete regulation of transcription from RNA polymerase II promoter by glucose `http://purl.obolibrary.org/obo/GO_0000430`

Removed

obsolete regulation of transcription from RNA polymerase II promoter by glucose definition “Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.”
- has cross-reference “GOC:krc”
obsolete regulation of transcription from RNA polymerase II promoter by glucose label “regulation of transcription from RNA polymerase II promoter by glucose”
obsolete regulation of transcription from RNA polymerase II promoter by glucose SubClassOf obsolete carbon catabolite regulation of transcription from RNA polymerase II promoter
obsolete regulation of transcription from RNA polymerase II promoter by glucose SubClassOf regulation of transcription by glucose

Added

obsolete regulation of transcription from RNA polymerase II promoter by glucose term tracker item “https://github.com/geneontology/go-ontology/issues/21442”^^anyURI
obsolete regulation of transcription from RNA polymerase II promoter by glucose consider regulation of transcription by RNA polymerase II
obsolete regulation of transcription from RNA polymerase II promoter by glucose definition “OBSOLETE. Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.”
- has cross-reference “GOC:krc”
obsolete regulation of transcription from RNA polymerase II promoter by glucose deprecated true
obsolete regulation of transcription from RNA polymerase II promoter by glucose comment “The reason for obsoletion is that these terms represent GO-CAM models.”
obsolete regulation of transcription from RNA polymerase II promoter by glucose label “obsolete regulation of transcription from RNA polymerase II promoter by glucose”

obsolete resveratrol binding `http://purl.obolibrary.org/obo/GO_1905594`

Removed

obsolete resveratrol binding conformsTo binding.yaml

obsolete sarcinapterin metabolic process `http://purl.obolibrary.org/obo/GO_1900867`

Removed

obsolete sarcinapterin metabolic process conformsTo metabolic_process.yaml

obsolete seryl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006434`

Removed

obsolete seryl-tRNA aminoacylation definition “The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of a serine-accetping tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete seryl-tRNA aminoacylation label “seryl-tRNA aminoacylation”
obsolete seryl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete seryl-tRNA aminoacylation SubClassOf has part some conversion of seryl-tRNAsec to selenocys-tRNAsec
obsolete seryl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete seryl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete seryl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete seryl-tRNA aminoacylation definition “OBSOLETE. The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of a serine-accetping tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete seryl-tRNA aminoacylation deprecated true
obsolete seryl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004828 serine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete seryl-tRNA aminoacylation label “obsolete seryl-tRNA aminoacylation”

obsolete styrene metabolic process `http://purl.obolibrary.org/obo/GO_0018966`

Removed

obsolete styrene metabolic process conformsTo metabolic_process.yaml

obsolete substrate localization to autophagosome `http://purl.obolibrary.org/obo/GO_0061753`

Removed

obsolete substrate localization to autophagosome definition “The localization process by which an autophagic substrate is delivered to a forming autophagosome.”
- has cross-reference “PMID:23545414”
- has cross-reference “GOC:dph”
- has cross-reference “GOC:PARL”
- has cross-reference “GOC:pad”
obsolete substrate localization to autophagosome label “substrate localization to autophagosome”
obsolete substrate localization to autophagosome SubClassOf establishment of localization in cell
obsolete substrate localization to autophagosome SubClassOf part of some autophagosome assembly
obsolete substrate localization to autophagosome SubClassOf in taxon some Eukaryota

Added

obsolete substrate localization to autophagosome term tracker item “https://github.com/geneontology/go-ontology/issues/32304”^^anyURI
obsolete substrate localization to autophagosome definition “OBSOLETE. The localization process by which an autophagic substrate is delivered to a forming autophagosome.”
- has cross-reference “PMID:23545414”
- has cross-reference “GOC:dph”
- has cross-reference “GOC:PARL”
- has cross-reference “GOC:pad”
obsolete substrate localization to autophagosome deprecated true
obsolete substrate localization to autophagosome comment “The reason for obsoletion is that this term was an unnecessary grouping term: localization terms that are not transport terms are largely uninformative about biological process. The intended biology in every observed use is better captured by a specific selective-autophagy term (e.g. mitophagy, glycophagy, reticulophagy). See the annotation review at https://github.com/geneontology/go-annotation/issues/6497 for per-annotation transfer recommendations.”
obsolete substrate localization to autophagosome label “obsolete substrate localization to autophagosome”

obsolete tRNA threonylcarbamoyladenosine metabolic process `http://purl.obolibrary.org/obo/GO_0070525`

Removed

obsolete tRNA threonylcarbamoyladenosine metabolic process conformsTo metabolic_process.yaml

obsolete tatiopterin biosynthetic process `http://purl.obolibrary.org/obo/GO_1900870`

Removed

obsolete tatiopterin biosynthetic process conformsTo biosynthetic_process.yaml

obsolete tatiopterin metabolic process `http://purl.obolibrary.org/obo/GO_1900869`

Removed

obsolete tatiopterin metabolic process conformsTo metabolic_process.yaml

obsolete thioredoxin peroxidase activity `http://purl.obolibrary.org/obo/GO_0008379`

Removed

obsolete thioredoxin peroxidase activity has cross-reference “MetaCyc:RXN0-267”
obsolete thioredoxin peroxidase activity has cross-reference “RHEA:63528”
obsolete thioredoxin peroxidase activity exactMatch 63528
obsolete thioredoxin peroxidase activity definition “Catalysis of the reaction: [thioredoxin]-dithiol + H2O2 = [thioredoxin]-disulfide + H2O.”
- has cross-reference “RHEA:63528”
obsolete thioredoxin peroxidase activity label “thioredoxin peroxidase activity”
obsolete thioredoxin peroxidase activity SubClassOf thioredoxin-dependent peroxiredoxin activity
obsolete thioredoxin peroxidase activity SubClassOf has participant some water
obsolete thioredoxin peroxidase activity SubClassOf has participant some hydrogen peroxide
obsolete thioredoxin peroxidase activity SubClassOf has participant some L-cysteine residue
obsolete thioredoxin peroxidase activity SubClassOf has participant some L-cystine residue

Added

obsolete thioredoxin peroxidase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32388”^^anyURI
obsolete thioredoxin peroxidase activity term replaced by thioredoxin-dependent peroxiredoxin activity
obsolete thioredoxin peroxidase activity definition “OBSOLETE. Catalysis of the reaction: [thioredoxin]-dithiol + H2O2 = [thioredoxin]-disulfide + H2O.”
- has cross-reference “RHEA:63528”
obsolete thioredoxin peroxidase activity deprecated true
obsolete thioredoxin peroxidase activity comment “This term was obsoleted because it is redundant with GO:0140824 thioredoxin-dependent peroxiredoxin activity. Both enzyme activities use thioredoxin; the nominal distinction was that GO:0008379/RHEA:63528 specified hydrogen peroxide as substrate while GO:0140824/RHEA:62620 uses a hydroperoxide (of which H2O2 is a subtype). RHEA:63528 has no proteins associated with it and this term has been misannotated for enzymes with broader hydroperoxide specificity.”
obsolete thioredoxin peroxidase activity label “obsolete thioredoxin peroxidase activity”

obsolete threonyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006435`

Removed

obsolete threonyl-tRNA aminoacylation definition “The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. The threonyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of a threonine-accetping tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete threonyl-tRNA aminoacylation label “threonyl-tRNA aminoacylation”
obsolete threonyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete threonyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete threonyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete threonyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete threonyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. The threonyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3’-OH group of a threonine-accetping tRNA.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete threonyl-tRNA aminoacylation deprecated true
obsolete threonyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004829 threonine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete threonyl-tRNA aminoacylation label “obsolete threonyl-tRNA aminoacylation”

obsolete toluene metabolic process `http://purl.obolibrary.org/obo/GO_0018970`

Removed

obsolete toluene metabolic process conformsTo metabolic_process.yaml

obsolete transport-coupled glycolytic process through glucose-6-phosphate `http://purl.obolibrary.org/obo/GO_0061633`

Removed

obsolete transport-coupled glycolytic process through glucose-6-phosphate has cross-reference “MetaCyc:GLYCOLYSIS”
obsolete transport-coupled glycolytic process through glucose-6-phosphate definition “The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport.”
- has cross-reference “GOC:dph”
obsolete transport-coupled glycolytic process through glucose-6-phosphate label “transport-coupled glycolytic process through glucose-6-phosphate”
obsolete transport-coupled glycolytic process through glucose-6-phosphate EquivalentTo obsolete glycolytic process through glucose-6-phosphate and (starts with some protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity) and (has primary input some D-glucopyranose)
obsolete transport-coupled glycolytic process through glucose-6-phosphate SubClassOf glucose catabolic process
obsolete transport-coupled glycolytic process through glucose-6-phosphate SubClassOf obsolete glycolytic process through glucose-6-phosphate
obsolete transport-coupled glycolytic process through glucose-6-phosphate SubClassOf starts with some protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity

Added

obsolete transport-coupled glycolytic process through glucose-6-phosphate term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
obsolete transport-coupled glycolytic process through glucose-6-phosphate term replaced by glycolysis
obsolete transport-coupled glycolytic process through glucose-6-phosphate definition “OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport.”
- has cross-reference “GOC:dph”
obsolete transport-coupled glycolytic process through glucose-6-phosphate deprecated true
obsolete transport-coupled glycolytic process through glucose-6-phosphate comment “The reason for obsoletion is that this term represents a GO-CAM model.”
obsolete transport-coupled glycolytic process through glucose-6-phosphate label “obsolete transport-coupled glycolytic process through glucose-6-phosphate”

obsolete tri-n-butyltin metabolic process `http://purl.obolibrary.org/obo/GO_0018944`

Removed

obsolete tri-n-butyltin metabolic process conformsTo metabolic_process.yaml

obsolete tridecane metabolic process `http://purl.obolibrary.org/obo/GO_1900631`

Removed

obsolete tridecane metabolic process conformsTo metabolic_process.yaml

obsolete tryptophanyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006436`

Removed

obsolete tryptophanyl-tRNA aminoacylation definition “The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. The tryptophanyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a tryptophan-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete tryptophanyl-tRNA aminoacylation label “tryptophanyl-tRNA aminoacylation”
obsolete tryptophanyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete tryptophanyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete tryptophanyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete tryptophanyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete tryptophanyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. The tryptophanyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a tryptophan-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete tryptophanyl-tRNA aminoacylation deprecated true
obsolete tryptophanyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004830 tryptophan-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete tryptophanyl-tRNA aminoacylation label “obsolete tryptophanyl-tRNA aminoacylation”

obsolete tyrosyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006437`

Removed

obsolete tyrosyl-tRNA aminoacylation definition “The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a tyrosine-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete tyrosyl-tRNA aminoacylation label “tyrosyl-tRNA aminoacylation”
obsolete tyrosyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete tyrosyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete tyrosyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete tyrosyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete tyrosyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a tyrosine-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete tyrosyl-tRNA aminoacylation deprecated true
obsolete tyrosyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004831 tyrosine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete tyrosyl-tRNA aminoacylation label “obsolete tyrosyl-tRNA aminoacylation”

obsolete valyl-tRNA aminoacylation `http://purl.obolibrary.org/obo/GO_0006438`

Removed

obsolete valyl-tRNA aminoacylation definition “The process of coupling valine to valyl-tRNA, catalyzed by valyl-tRNA synthetase. The valyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a valine-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete valyl-tRNA aminoacylation label “valyl-tRNA aminoacylation”
obsolete valyl-tRNA aminoacylation SubClassOf tRNA aminoacylation for protein translation
obsolete valyl-tRNA aminoacylation SubClassOf in taxon some cellular organisms

Added

obsolete valyl-tRNA aminoacylation term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
obsolete valyl-tRNA aminoacylation term replaced by tRNA aminoacylation for protein translation
obsolete valyl-tRNA aminoacylation definition “OBSOLETE. The process of coupling valine to valyl-tRNA, catalyzed by valyl-tRNA synthetase. The valyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a valine-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- has cross-reference “ISBN:0716730510”
- has cross-reference “GOC:mcc”
obsolete valyl-tRNA aminoacylation deprecated true
obsolete valyl-tRNA aminoacylation comment “The reason for obsoletion is that this term restates an existing molecular function, GO:0004832 valine-tRNA ligase activity, and adds nothing beyond it. Gene products should be annotated to that molecular function; the biological process is covered by GO:0006418 tRNA aminoacylation for protein translation.”
obsolete valyl-tRNA aminoacylation label “obsolete valyl-tRNA aminoacylation”

obsolete venom-mediated activation of pH-gated ion channel activity `http://purl.obolibrary.org/obo/GO_0044734`

Removed

obsolete venom-mediated activation of pH-gated ion channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated activation of pH-gated ion channel activity definition “A process in which an organism initiates, promotes, or enhances the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:23034652”
- has cross-reference “GOC:jl”
obsolete venom-mediated activation of pH-gated ion channel activity label “venom-mediated activation of pH-gated ion channel activity”
obsolete venom-mediated activation of pH-gated ion channel activity EquivalentTo venom-mediated perturbation of biological process and (positively regulates in another organism some pH-gated monoatomic ion channel activity)
obsolete venom-mediated activation of pH-gated ion channel activity SubClassOf obsolete venom-mediated perturbation of pH-gated ion channel activity
obsolete venom-mediated activation of pH-gated ion channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated activation of pH-gated ion channel activity SubClassOf positively regulates in another organism some pH-gated monoatomic ion channel activity

Added

obsolete venom-mediated activation of pH-gated ion channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated activation of pH-gated ion channel activity consider channel activator activity
obsolete venom-mediated activation of pH-gated ion channel activity definition “OBSOLETE. A process in which an organism initiates, promotes, or enhances the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:23034652”
- has cross-reference “GOC:jl”
obsolete venom-mediated activation of pH-gated ion channel activity deprecated true
obsolete venom-mediated activation of pH-gated ion channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated activation of pH-gated ion channel activity label “obsolete venom-mediated activation of pH-gated ion channel activity”

obsolete venom-mediated activation of voltage-gated sodium channel activity `http://purl.obolibrary.org/obo/GO_0044494`

Removed

obsolete venom-mediated activation of voltage-gated sodium channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated activation of voltage-gated sodium channel activity definition “A process in which an organism initiates, promotes, or enhances the activity of a voltage-gated sodium channel in another organism via the action of a venom.”
- has cross-reference “PMID:21781281”
- has cross-reference “GOC:fj”
- has cross-reference “GOC:jl”
obsolete venom-mediated activation of voltage-gated sodium channel activity label “venom-mediated activation of voltage-gated sodium channel activity”
obsolete venom-mediated activation of voltage-gated sodium channel activity EquivalentTo venom-mediated perturbation of biological process and (positively regulates in another organism some voltage-gated sodium channel activity)
obsolete venom-mediated activation of voltage-gated sodium channel activity SubClassOf obsolete venom-mediated perturbation of voltage-gated sodium channel activity
obsolete venom-mediated activation of voltage-gated sodium channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated activation of voltage-gated sodium channel activity SubClassOf positively regulates in another organism some voltage-gated sodium channel activity

Added

obsolete venom-mediated activation of voltage-gated sodium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated activation of voltage-gated sodium channel activity consider sodium channel activator activity
obsolete venom-mediated activation of voltage-gated sodium channel activity definition “OBSOLETE. A process in which an organism initiates, promotes, or enhances the activity of a voltage-gated sodium channel in another organism via the action of a venom.”
- has cross-reference “PMID:21781281”
- has cross-reference “GOC:fj”
- has cross-reference “GOC:jl”
obsolete venom-mediated activation of voltage-gated sodium channel activity deprecated true
obsolete venom-mediated activation of voltage-gated sodium channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated activation of voltage-gated sodium channel activity label “obsolete venom-mediated activation of voltage-gated sodium channel activity”

obsolete venom-mediated inhibition of calcium channel activity `http://purl.obolibrary.org/obo/GO_0044473`

Removed

obsolete venom-mediated inhibition of calcium channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated inhibition of calcium channel activity definition “A process in which an organism inhibits or disrupts the activity of a calcium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:20920515”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of calcium channel activity label “venom-mediated inhibition of calcium channel activity”
obsolete venom-mediated inhibition of calcium channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some calcium channel activity)
obsolete venom-mediated inhibition of calcium channel activity SubClassOf obsolete venom-mediated perturbation of calcium channel activity
obsolete venom-mediated inhibition of calcium channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated inhibition of calcium channel activity SubClassOf negatively regulates in another organism some calcium channel activity

Added

obsolete venom-mediated inhibition of calcium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated inhibition of calcium channel activity consider calcium channel inhibitor activity
obsolete venom-mediated inhibition of calcium channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a calcium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:20920515”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of calcium channel activity deprecated true
obsolete venom-mediated inhibition of calcium channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated inhibition of calcium channel activity label “obsolete venom-mediated inhibition of calcium channel activity”

obsolete venom-mediated inhibition of high voltage-gated calcium channel activity `http://purl.obolibrary.org/obo/GO_0044475`

Removed

obsolete venom-mediated inhibition of high voltage-gated calcium channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated inhibition of high voltage-gated calcium channel activity definition “A process in which an organism inhibits or disrupts the activity of a high voltage-gated calcium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:20920515”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of high voltage-gated calcium channel activity label “venom-mediated inhibition of high voltage-gated calcium channel activity”
obsolete venom-mediated inhibition of high voltage-gated calcium channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some high voltage-gated calcium channel activity)
obsolete venom-mediated inhibition of high voltage-gated calcium channel activity SubClassOf obsolete venom-mediated inhibition of voltage-gated calcium channel activity
obsolete venom-mediated inhibition of high voltage-gated calcium channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated inhibition of high voltage-gated calcium channel activity SubClassOf negatively regulates in another organism some high voltage-gated calcium channel activity

Added

obsolete venom-mediated inhibition of high voltage-gated calcium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated inhibition of high voltage-gated calcium channel activity consider calcium channel inhibitor activity
obsolete venom-mediated inhibition of high voltage-gated calcium channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a high voltage-gated calcium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:20920515”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of high voltage-gated calcium channel activity deprecated true
obsolete venom-mediated inhibition of high voltage-gated calcium channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated inhibition of high voltage-gated calcium channel activity label “obsolete venom-mediated inhibition of high voltage-gated calcium channel activity”

obsolete venom-mediated inhibition of low voltage-gated calcium channel activity `http://purl.obolibrary.org/obo/GO_0044476`

Removed

obsolete venom-mediated inhibition of low voltage-gated calcium channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated inhibition of low voltage-gated calcium channel activity definition “A process in which an organism inhibits or disrupts the activity of a low voltage-gated calcium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:20920515”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of low voltage-gated calcium channel activity label “venom-mediated inhibition of low voltage-gated calcium channel activity”
obsolete venom-mediated inhibition of low voltage-gated calcium channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some low voltage-gated calcium channel activity)
obsolete venom-mediated inhibition of low voltage-gated calcium channel activity SubClassOf obsolete venom-mediated inhibition of voltage-gated calcium channel activity
obsolete venom-mediated inhibition of low voltage-gated calcium channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated inhibition of low voltage-gated calcium channel activity SubClassOf negatively regulates in another organism some low voltage-gated calcium channel activity

Added

obsolete venom-mediated inhibition of low voltage-gated calcium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated inhibition of low voltage-gated calcium channel activity consider calcium channel inhibitor activity
obsolete venom-mediated inhibition of low voltage-gated calcium channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a low voltage-gated calcium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:20920515”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of low voltage-gated calcium channel activity deprecated true
obsolete venom-mediated inhibition of low voltage-gated calcium channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated inhibition of low voltage-gated calcium channel activity label “obsolete venom-mediated inhibition of low voltage-gated calcium channel activity”

obsolete venom-mediated inhibition of pH-gated ion channel activity `http://purl.obolibrary.org/obo/GO_0044735`

Removed

obsolete venom-mediated inhibition of pH-gated ion channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated inhibition of pH-gated ion channel activity definition “A process in which an organism inhibits or disrupts the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:23034652”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of pH-gated ion channel activity label “venom-mediated inhibition of pH-gated ion channel activity”
obsolete venom-mediated inhibition of pH-gated ion channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some pH-gated monoatomic ion channel activity)
obsolete venom-mediated inhibition of pH-gated ion channel activity SubClassOf obsolete venom-mediated perturbation of pH-gated ion channel activity
obsolete venom-mediated inhibition of pH-gated ion channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated inhibition of pH-gated ion channel activity SubClassOf negatively regulates in another organism some pH-gated monoatomic ion channel activity

Added

obsolete venom-mediated inhibition of pH-gated ion channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated inhibition of pH-gated ion channel activity consider ion channel inhibitor activity
obsolete venom-mediated inhibition of pH-gated ion channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:23034652”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of pH-gated ion channel activity deprecated true
obsolete venom-mediated inhibition of pH-gated ion channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated inhibition of pH-gated ion channel activity label “obsolete venom-mediated inhibition of pH-gated ion channel activity”

obsolete venom-mediated inhibition of voltage-gated calcium channel activity `http://purl.obolibrary.org/obo/GO_0044474`

Removed

obsolete venom-mediated inhibition of voltage-gated calcium channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated inhibition of voltage-gated calcium channel activity definition “A process in which an organism inhibits or disrupts the activity of a voltage-gated calcium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:20920515”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of voltage-gated calcium channel activity label “venom-mediated inhibition of voltage-gated calcium channel activity”
obsolete venom-mediated inhibition of voltage-gated calcium channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some voltage-gated calcium channel activity)
obsolete venom-mediated inhibition of voltage-gated calcium channel activity SubClassOf obsolete venom-mediated inhibition of calcium channel activity
obsolete venom-mediated inhibition of voltage-gated calcium channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated inhibition of voltage-gated calcium channel activity SubClassOf negatively regulates in another organism some voltage-gated calcium channel activity

Added

obsolete venom-mediated inhibition of voltage-gated calcium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated inhibition of voltage-gated calcium channel activity consider calcium channel inhibitor activity
obsolete venom-mediated inhibition of voltage-gated calcium channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a voltage-gated calcium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:20920515”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of voltage-gated calcium channel activity deprecated true
obsolete venom-mediated inhibition of voltage-gated calcium channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated inhibition of voltage-gated calcium channel activity label “obsolete venom-mediated inhibition of voltage-gated calcium channel activity”

obsolete venom-mediated inhibition of voltage-gated potassium channel activity `http://purl.obolibrary.org/obo/GO_0044562`

Removed

obsolete venom-mediated inhibition of voltage-gated potassium channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated inhibition of voltage-gated potassium channel activity definition “A process in which an organism inhibits or disrupts the activity of a voltage-gated potassium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of voltage-gated potassium channel activity label “venom-mediated inhibition of voltage-gated potassium channel activity”
obsolete venom-mediated inhibition of voltage-gated potassium channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some voltage-gated potassium channel activity)
obsolete venom-mediated inhibition of voltage-gated potassium channel activity SubClassOf obsolete venom-mediated perturbation of voltage-gated potassium channel activity
obsolete venom-mediated inhibition of voltage-gated potassium channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated inhibition of voltage-gated potassium channel activity SubClassOf negatively regulates in another organism some voltage-gated potassium channel activity

Added

obsolete venom-mediated inhibition of voltage-gated potassium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated inhibition of voltage-gated potassium channel activity consider voltage-gated potassium channel inhibitor activity
obsolete venom-mediated inhibition of voltage-gated potassium channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a voltage-gated potassium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of voltage-gated potassium channel activity deprecated true
obsolete venom-mediated inhibition of voltage-gated potassium channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated inhibition of voltage-gated potassium channel activity label “obsolete venom-mediated inhibition of voltage-gated potassium channel activity”

obsolete venom-mediated inhibition of voltage-gated sodium channel activity `http://purl.obolibrary.org/obo/GO_0044493`

Removed

obsolete venom-mediated inhibition of voltage-gated sodium channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated inhibition of voltage-gated sodium channel activity definition “A process in which an organism inhibits or disrupts the activity of a voltage-gated sodium channel in another organism via the action of a venom.”
- has cross-reference “PMID:21781281”
- has cross-reference “GOC:fj”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of voltage-gated sodium channel activity label “venom-mediated inhibition of voltage-gated sodium channel activity”
obsolete venom-mediated inhibition of voltage-gated sodium channel activity EquivalentTo venom-mediated perturbation of biological process and (negatively regulates in another organism some voltage-gated sodium channel activity)
obsolete venom-mediated inhibition of voltage-gated sodium channel activity SubClassOf obsolete venom-mediated perturbation of voltage-gated sodium channel activity
obsolete venom-mediated inhibition of voltage-gated sodium channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated inhibition of voltage-gated sodium channel activity SubClassOf negatively regulates in another organism some voltage-gated sodium channel activity

Added

obsolete venom-mediated inhibition of voltage-gated sodium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated inhibition of voltage-gated sodium channel activity consider sodium channel inhibitor activity
obsolete venom-mediated inhibition of voltage-gated sodium channel activity definition “OBSOLETE. A process in which an organism inhibits or disrupts the activity of a voltage-gated sodium channel in another organism via the action of a venom.”
- has cross-reference “PMID:21781281”
- has cross-reference “GOC:fj”
- has cross-reference “GOC:jl”
obsolete venom-mediated inhibition of voltage-gated sodium channel activity deprecated true
obsolete venom-mediated inhibition of voltage-gated sodium channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated inhibition of voltage-gated sodium channel activity label “obsolete venom-mediated inhibition of voltage-gated sodium channel activity”

obsolete venom-mediated perturbation of calcium channel activity `http://purl.obolibrary.org/obo/GO_0044472`

Removed

obsolete venom-mediated perturbation of calcium channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated perturbation of calcium channel activity definition “A process in which an organism alters or subverts the activity of a calcium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:20920515”
- has cross-reference “GOC:jl”
obsolete venom-mediated perturbation of calcium channel activity label “venom-mediated perturbation of calcium channel activity”
obsolete venom-mediated perturbation of calcium channel activity EquivalentTo venom-mediated perturbation of biological process and (regulates in another organism some calcium channel activity)
obsolete venom-mediated perturbation of calcium channel activity SubClassOf obsolete venom-mediated perturbation of ion channel activity
obsolete venom-mediated perturbation of calcium channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated perturbation of calcium channel activity SubClassOf regulates in another organism some calcium channel activity

Added

obsolete venom-mediated perturbation of calcium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated perturbation of calcium channel activity consider calcium channel regulator activity
obsolete venom-mediated perturbation of calcium channel activity definition “OBSOLETE. A process in which an organism alters or subverts the activity of a calcium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:20920515”
- has cross-reference “GOC:jl”
obsolete venom-mediated perturbation of calcium channel activity deprecated true
obsolete venom-mediated perturbation of calcium channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated perturbation of calcium channel activity label “obsolete venom-mediated perturbation of calcium channel activity”

obsolete venom-mediated perturbation of ion channel activity `http://purl.obolibrary.org/obo/GO_0044560`

Removed

obsolete venom-mediated perturbation of ion channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated perturbation of ion channel activity definition “A process in which an organism alters or subverts the activity of an ion channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “GOC:jl”
obsolete venom-mediated perturbation of ion channel activity label “venom-mediated perturbation of ion channel activity”
obsolete venom-mediated perturbation of ion channel activity EquivalentTo venom-mediated perturbation of biological process and (regulates in another organism some monoatomic ion channel activity)
obsolete venom-mediated perturbation of ion channel activity SubClassOf venom-mediated perturbation of biological process
obsolete venom-mediated perturbation of ion channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated perturbation of ion channel activity SubClassOf regulates in another organism some monoatomic ion channel activity

Added

obsolete venom-mediated perturbation of ion channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated perturbation of ion channel activity definition “OBSOLETE. A process in which an organism alters or subverts the activity of an ion channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “GOC:jl”
obsolete venom-mediated perturbation of ion channel activity deprecated true
obsolete venom-mediated perturbation of ion channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated perturbation of ion channel activity label “obsolete venom-mediated perturbation of ion channel activity”

obsolete venom-mediated perturbation of pH-gated ion channel activity `http://purl.obolibrary.org/obo/GO_0044733`

Removed

obsolete venom-mediated perturbation of pH-gated ion channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated perturbation of pH-gated ion channel activity definition “A process in which an organism alters or subverts the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:23034652”
- has cross-reference “GOC:jl”
obsolete venom-mediated perturbation of pH-gated ion channel activity label “venom-mediated perturbation of pH-gated ion channel activity”
obsolete venom-mediated perturbation of pH-gated ion channel activity EquivalentTo venom-mediated perturbation of biological process and (regulates in another organism some pH-gated monoatomic ion channel activity)
obsolete venom-mediated perturbation of pH-gated ion channel activity SubClassOf obsolete venom-mediated perturbation of ion channel activity
obsolete venom-mediated perturbation of pH-gated ion channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated perturbation of pH-gated ion channel activity SubClassOf regulates in another organism some pH-gated monoatomic ion channel activity

Added

obsolete venom-mediated perturbation of pH-gated ion channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated perturbation of pH-gated ion channel activity consider ion channel regulator activity
obsolete venom-mediated perturbation of pH-gated ion channel activity definition “OBSOLETE. A process in which an organism alters or subverts the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “PMID:23034652”
- has cross-reference “GOC:jl”
obsolete venom-mediated perturbation of pH-gated ion channel activity deprecated true
obsolete venom-mediated perturbation of pH-gated ion channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated perturbation of pH-gated ion channel activity label “obsolete venom-mediated perturbation of pH-gated ion channel activity”

obsolete venom-mediated perturbation of voltage-gated potassium channel activity `http://purl.obolibrary.org/obo/GO_0044559`

Removed

obsolete venom-mediated perturbation of voltage-gated potassium channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated perturbation of voltage-gated potassium channel activity definition “A process in which an organism alters or subverts the activity of a voltage-gated potassium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “GOC:jl”
obsolete venom-mediated perturbation of voltage-gated potassium channel activity label “venom-mediated perturbation of voltage-gated potassium channel activity”
obsolete venom-mediated perturbation of voltage-gated potassium channel activity EquivalentTo venom-mediated perturbation of biological process and (regulates in another organism some voltage-gated potassium channel activity)
obsolete venom-mediated perturbation of voltage-gated potassium channel activity SubClassOf obsolete venom-mediated perturbation of ion channel activity
obsolete venom-mediated perturbation of voltage-gated potassium channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated perturbation of voltage-gated potassium channel activity SubClassOf regulates in another organism some voltage-gated potassium channel activity

Added

obsolete venom-mediated perturbation of voltage-gated potassium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated perturbation of voltage-gated potassium channel activity consider potassium channel regulator activity
obsolete venom-mediated perturbation of voltage-gated potassium channel activity definition “OBSOLETE. A process in which an organism alters or subverts the activity of a voltage-gated potassium channel in another organism via the action of a venom.”
- has cross-reference “GOC:fj”
- has cross-reference “GOC:jl”
obsolete venom-mediated perturbation of voltage-gated potassium channel activity deprecated true
obsolete venom-mediated perturbation of voltage-gated potassium channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated perturbation of voltage-gated potassium channel activity label “obsolete venom-mediated perturbation of voltage-gated potassium channel activity”

obsolete venom-mediated perturbation of voltage-gated sodium channel activity `http://purl.obolibrary.org/obo/GO_0044492`

Removed

obsolete venom-mediated perturbation of voltage-gated sodium channel activity never in taxon Schizosaccharomyces
obsolete venom-mediated perturbation of voltage-gated sodium channel activity definition “A process in which an organism alters or subverts the activity of a voltage-gated sodium channel in another organism via the action of a venom.”
- has cross-reference “PMID:21781281”
- has cross-reference “GOC:fj”
- has cross-reference “GOC:jl”
obsolete venom-mediated perturbation of voltage-gated sodium channel activity label “venom-mediated perturbation of voltage-gated sodium channel activity”
obsolete venom-mediated perturbation of voltage-gated sodium channel activity EquivalentTo venom-mediated perturbation of biological process and (regulates in another organism some voltage-gated sodium channel activity)
obsolete venom-mediated perturbation of voltage-gated sodium channel activity SubClassOf obsolete venom-mediated perturbation of ion channel activity
obsolete venom-mediated perturbation of voltage-gated sodium channel activity SubClassOf not (in taxon some Schizosaccharomyces)
obsolete venom-mediated perturbation of voltage-gated sodium channel activity SubClassOf regulates in another organism some voltage-gated sodium channel activity

Added

obsolete venom-mediated perturbation of voltage-gated sodium channel activity term tracker item “https://github.com/geneontology/go-ontology/issues/32401”^^anyURI
obsolete venom-mediated perturbation of voltage-gated sodium channel activity consider sodium channel regulator activity
obsolete venom-mediated perturbation of voltage-gated sodium channel activity definition “OBSOLETE. A process in which an organism alters or subverts the activity of a voltage-gated sodium channel in another organism via the action of a venom.”
- has cross-reference “PMID:21781281”
- has cross-reference “GOC:fj”
- has cross-reference “GOC:jl”
obsolete venom-mediated perturbation of voltage-gated sodium channel activity deprecated true
obsolete venom-mediated perturbation of voltage-gated sodium channel activity comment “This term was obsoleted because it represents a molecular function.”
obsolete venom-mediated perturbation of voltage-gated sodium channel activity label “obsolete venom-mediated perturbation of voltage-gated sodium channel activity”

obsolete very long-chain fatty acid beta-oxidation `http://purl.obolibrary.org/obo/GO_0140493`

Removed

obsolete very long-chain fatty acid beta-oxidation definition “A fatty acid beta-oxidation pathway acting on a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons. The partway stars with the conversion of an acyl-CoA to a trans-2-enoyl-CoA, catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).”
- has cross-reference “PMID:17028011”
- has cross-reference “GOC:ha”
- has cross-reference “PMID:32169171”
obsolete very long-chain fatty acid beta-oxidation comment “While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).”
obsolete very long-chain fatty acid beta-oxidation label “very long-chain fatty acid beta-oxidation”
obsolete very long-chain fatty acid beta-oxidation SubClassOf very long-chain fatty acid catabolic process

Added

obsolete very long-chain fatty acid beta-oxidation term tracker item “https://github.com/geneontology/go-ontology/issues/32227”^^anyURI
obsolete very long-chain fatty acid beta-oxidation term replaced by very long-chain fatty acid catabolic process
obsolete very long-chain fatty acid beta-oxidation definition “OBSOLETE. A fatty acid beta-oxidation pathway acting on a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons. The partway stars with the conversion of an acyl-CoA to a trans-2-enoyl-CoA, catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).”
- has cross-reference “PMID:17028011”
- has cross-reference “GOC:ha”
- has cross-reference “PMID:32169171”
obsolete very long-chain fatty acid beta-oxidation deprecated true
obsolete very long-chain fatty acid beta-oxidation comment “This term was obsoleted because it represents the same process as very long-chain fatty acid catabolic process ; GO:0042760.”
obsolete very long-chain fatty acid beta-oxidation label “obsolete very long-chain fatty acid beta-oxidation”

ocellus development `http://purl.obolibrary.org/obo/GO_0008056`

Removed

ocellus development definition “The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects.”
- has cross-reference “http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004540”

Added

ocellus development term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
ocellus development definition “The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects.”
- has cross-reference “FBbt:00004505”

ocellus morphogenesis `http://purl.obolibrary.org/obo/GO_0048816`

Removed

ocellus morphogenesis definition “The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects.”
- has cross-reference “http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004540”

Added

ocellus morphogenesis term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
ocellus morphogenesis definition “The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects.”
- has cross-reference “FBbt:00004505”

organophosphate biosynthetic process `http://purl.obolibrary.org/obo/GO_0090407`

Added

organophosphate biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI
organophosphate biosynthetic process in_subset gocheck_do_not_annotate

organophosphate catabolic process `http://purl.obolibrary.org/obo/GO_0046434`

Added

organophosphate catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI
organophosphate catabolic process in_subset gocheck_do_not_annotate

organophosphate metabolic process `http://purl.obolibrary.org/obo/GO_0019637`

Added

organophosphate metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32294”^^anyURI
organophosphate metabolic process in_subset gocheck_do_not_annotate

otolith development `http://purl.obolibrary.org/obo/GO_0048840`

Removed

otolith development conformsTo anatomical_structure_development.yaml

otolith formation `http://purl.obolibrary.org/obo/GO_0032475`

Removed

otolith formation conformsTo anatomical_structure_formation.yaml

otolith morphogenesis `http://purl.obolibrary.org/obo/GO_0032474`

Removed

otolith morphogenesis conformsTo anatomical_structure_morphogenesis.yaml

outward rectifier potassium channel inhibitor activity `http://purl.obolibrary.org/obo/GO_0140628`

Removed

outward rectifier potassium channel inhibitor activity SubClassOf potassium channel inhibitor activity

Added

outward rectifier potassium channel inhibitor activity SubClassOf voltage-gated potassium channel inhibitor activity

oxygen carrier activity `http://purl.obolibrary.org/obo/GO_0005344`

Added

oxygen carrier activity conformsTo molecular_carrier_activity.yaml

palmitoyl hydrolase activity `http://purl.obolibrary.org/obo/GO_0098599`

Removed

palmitoyl hydrolase activity SubClassOf part of some obsolete macromolecule depalmitoylation

paranodal junction maintenance `http://purl.obolibrary.org/obo/GO_1990227`

Added

paranodal junction maintenance never in taxon Fungi
paranodal junction maintenance SubClassOf not (in taxon some Fungi)

perforant pathway to dentate granule cell synapse `http://purl.obolibrary.org/obo/GO_0140240`

Removed

perforant pathway to dentate granule cell synapse label “perforant pathway to dendrate granule cell synapse”

Added

perforant pathway to dentate granule cell synapse label “perforant pathway to dentate granule cell synapse”

periodic partitioning by pair rule gene `http://purl.obolibrary.org/obo/GO_0007366`

Removed

periodic partitioning by pair rule gene definition “Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”
- has cross-reference “ISBN:0632030488”

Added

periodic partitioning by pair rule gene term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
periodic partitioning by pair rule gene definition “Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “ISBN:0632030488”

peroxiredoxin activity `http://purl.obolibrary.org/obo/GO_0051920`

Removed

peroxiredoxin activity has cross-reference “RHEA:62624”
peroxiredoxin activity has cross-reference “RHEA:62640”
peroxiredoxin activity narrowMatch 62624
peroxiredoxin activity narrowMatch 62640
peroxiredoxin activity definition “Catalysis of the reaction: [protein]-dithol + ROOH = [protein]-disulfide + H2O + ROH.”
- has cross-reference “RHEA:10008”

Added

peroxiredoxin activity term tracker item “https://github.com/geneontology/go-ontology/issues/32405”^^anyURI
peroxiredoxin activity definition “Catalysis of the reaction: [protein]-dithiol + ROOH = [protein]-disulfide + H2O + ROH.”
- has cross-reference “RHEA:10008”

peroxisomal protein quality control `http://purl.obolibrary.org/obo/GO_0170079`

Added

Class: peroxisomal protein quality control
peroxisomal protein quality control term tracker item “https://github.com/geneontology/go-ontology/issues/32442”^^anyURI
peroxisomal protein quality control created by “ew”
peroxisomal protein quality control creation date “2026-08-12T16:13:58Z”
peroxisomal protein quality control has_obo_namespace “biological_process”
peroxisomal protein quality control id “GO:0170079”
peroxisomal protein quality control definition “The chemical reactions and pathways resulting in the breakdown of dysfunctional peroxisomal proteins, independent of pexophagy.”
- has cross-reference “PMID:25305535”
- has cross-reference “PMID:37552037”
- has cross-reference “PMID:19538506”
peroxisomal protein quality control label “peroxisomal protein quality control”
peroxisomal protein quality control SubClassOf protein quality control
peroxisomal protein quality control SubClassOf protein catabolic process

phagocytosis, engulfment `http://purl.obolibrary.org/obo/GO_0006911`

Added

phagocytosis, engulfment term tracker item “https://github.com/geneontology/go-ontology/issues/32152”^^anyURI
phagocytosis, engulfment SubClassOf preceded by some phagocytosis, recognition

phagolysosome assembly `http://purl.obolibrary.org/obo/GO_0001845`

Removed

phagolysosome assembly SubClassOf part of some phagocytosis

phagolysosome membrane `http://purl.obolibrary.org/obo/GO_0061474`

Removed

phagolysosome membrane definition “The lipid bilayer surrounding a phagolysosome.”
- has cross-reference “GOC:dph”
- has cross-reference “PMID:22073313”

Added

phagolysosome membrane has exact synonym “phagolysosome vesicle membrane”
phagolysosome membrane definition “The lipid bilayer surrounding a phagolysosome.”
- has cross-reference “GOC:dph”
- has cross-reference “PMID:22073313”
- has cross-reference “PMID:29471269”

phagophore membrane `http://purl.obolibrary.org/obo/GO_7770114`

Added

Class: phagophore membrane
phagophore membrane term tracker item “https://github.com/geneontology/go-ontology/issues/29437”^^anyURI
phagophore membrane created by “ai4c-agent”
phagophore membrane creation date “2026-08-19T23:59:26Z”
phagophore membrane has_obo_namespace “cellular_component”
phagophore membrane id “GO:7770114”
phagophore membrane definition “A membrane that is part of a phagophore.”
- has cross-reference “PMID:33773106”
- has cross-reference “PMID:23217709”
phagophore membrane comment “Covers the membrane of the nascent phagophore, including membrane contributed by Atg9/ATG9A-containing vesicles once they have been incorporated into the phagophore, and the membrane of the expanding cup-shaped structure. After the structure has closed, annotate to autophagosome membrane (GO:0000421) instead. Do not use for Atg9/ATG9A-containing vesicles themselves, either before or after their recruitment to the phagophore assembly site: a vesicle is a membrane-bounded structure, not a membrane.”
phagophore membrane label “phagophore membrane”
phagophore membrane SubClassOf membrane
phagophore membrane SubClassOf part of some phagophore
phagophore membrane SubClassOf in taxon some cellular organisms

phagosome maturation `http://purl.obolibrary.org/obo/GO_0090382`

Removed

phagosome maturation SubClassOf starts with some exocytosis

Added

phagosome maturation term tracker item “https://github.com/geneontology/go-ontology/issues/32152”^^anyURI
phagosome maturation SubClassOf part of some phagocytosis
phagosome maturation SubClassOf preceded by some phagocytosis, engulfment

phenylacetyl-CoA 1,2-epoxidase complex `http://purl.obolibrary.org/obo/GO_0062077`

Removed

phenylacetyl-CoA 1,2-epoxidase complex definition “A protein complex capable of catalysing the reaction: phenylacetyl-CoA + H+ + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+.”
- has cross-reference “GOC:bhm”
- has cross-reference “PMID:21247899”

Added

phenylacetyl-CoA 1,2-epoxidase complex definition “A protein complex capable of catalyzing the reaction: phenylacetyl-CoA + H+ + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+.”
- has cross-reference “GOC:bhm”
- has cross-reference “PMID:21247899”

phosphatidylcholine flippase activity `http://purl.obolibrary.org/obo/GO_0140345`

Added

phosphatidylcholine flippase activity conformsTo lipid_flippase_activity.yaml

phosphatidylcholine floppase activity `http://purl.obolibrary.org/obo/GO_0090554`

Added

phosphatidylcholine floppase activity conformsTo lipid_floppase_activity.yaml

phosphatidylcholine intramembrane carrier activity `http://purl.obolibrary.org/obo/GO_0008525`

Added

phosphatidylcholine intramembrane carrier activity conformsTo intramembrane_lipid_carrier_activity.yaml

phosphatidylcholine transfer activity `http://purl.obolibrary.org/obo/GO_0120019`

Added

phosphatidylcholine transfer activity conformsTo intermembrane_lipid_transfer_activity.yaml

phosphocreatine biosynthetic process `http://purl.obolibrary.org/obo/GO_0046314`

Added

phosphocreatine biosynthetic process never in taxon Archaea
phosphocreatine biosynthetic process never in taxon Bacteria
phosphocreatine biosynthetic process never in taxon Viridiplantae
phosphocreatine biosynthetic process never in taxon Fungi
phosphocreatine biosynthetic process never in taxon Insecta
phosphocreatine biosynthetic process SubClassOf not (in taxon some Archaea)
phosphocreatine biosynthetic process SubClassOf not (in taxon some Bacteria)
phosphocreatine biosynthetic process SubClassOf not (in taxon some Viridiplantae)
phosphocreatine biosynthetic process SubClassOf not (in taxon some Fungi)
phosphocreatine biosynthetic process SubClassOf not (in taxon some Insecta)

phosphocreatine catabolic process `http://purl.obolibrary.org/obo/GO_0046315`

Added

phosphocreatine catabolic process never in taxon Archaea
phosphocreatine catabolic process never in taxon Bacteria
phosphocreatine catabolic process never in taxon Viridiplantae
phosphocreatine catabolic process never in taxon Fungi
phosphocreatine catabolic process never in taxon Insecta
phosphocreatine catabolic process SubClassOf not (in taxon some Archaea)
phosphocreatine catabolic process SubClassOf not (in taxon some Bacteria)
phosphocreatine catabolic process SubClassOf not (in taxon some Viridiplantae)
phosphocreatine catabolic process SubClassOf not (in taxon some Fungi)
phosphocreatine catabolic process SubClassOf not (in taxon some Insecta)

phosphocreatine metabolic process `http://purl.obolibrary.org/obo/GO_0006603`

Added

phosphocreatine metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/32279”^^anyURI
phosphocreatine metabolic process never in taxon Archaea
phosphocreatine metabolic process never in taxon Bacteria
phosphocreatine metabolic process never in taxon Viridiplantae
phosphocreatine metabolic process never in taxon Fungi
phosphocreatine metabolic process never in taxon Insecta
phosphocreatine metabolic process SubClassOf not (in taxon some Archaea)
phosphocreatine metabolic process SubClassOf not (in taxon some Bacteria)
phosphocreatine metabolic process SubClassOf not (in taxon some Viridiplantae)
phosphocreatine metabolic process SubClassOf not (in taxon some Fungi)
phosphocreatine metabolic process SubClassOf not (in taxon some Insecta)

phospholipid transfer activity `http://purl.obolibrary.org/obo/GO_0120014`

Added

phospholipid transfer activity conformsTo intermembrane_lipid_transfer_activity.yaml

phosphopantetheine-dependent carrier activity `http://purl.obolibrary.org/obo/GO_0140414`

Removed

phosphopantetheine-dependent carrier activity definition “Binding a substrate via a thioester at the terminal thiol of a covalentely linked phosphopantetheine prosthetic group and mediating protein-protein interactions with cognate enzymes for processing or offloading of the thiol-bound substrate.”
- has cross-reference “PMID:17502372”

Added

phosphopantetheine-dependent carrier activity definition “Binding a substrate via a thioester at the terminal thiol of a covalently linked phosphopantetheine prosthetic group and mediating protein-protein interactions with cognate enzymes for processing or offloading of the thiol-bound substrate.”
- has cross-reference “PMID:17502372”

phytanate-CoA ligase activity `http://purl.obolibrary.org/obo/GO_0050197`

Removed

phytanate-CoA ligase activity definition “Catalysis of the reaction: ATP + CoA + phytanate = AMP + diphosphate + H+ + phytanoyl-CoA.”
- has cross-reference “RHEA:21380”
- has cross-reference “EC:6.2.1.24”
phytanate-CoA ligase activity SubClassOf CoA-ligase activity

Added

phytanate-CoA ligase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32501”^^anyURI
phytanate-CoA ligase activity definition “Catalysis of the reaction: ATP + CoA + phytanate = AMP + diphosphate + H+ + phytanoyl-CoA.”
- has cross-reference “RHEA:21380”
phytanate-CoA ligase activity SubClassOf fatty acid-CoA ligase activity

plant anatomical entity `http://purl.obolibrary.org/obo/PO_0025131`

Added

plant anatomical entity definition “An anatomical entity that is or was part of a plant.”

plasmacytoid dendritic cell cytokine production `http://purl.obolibrary.org/obo/GO_0002373`

Removed

plasmacytoid dendritic cell cytokine production EquivalentTo cytokine production and (process has causal agent some plasmacytoid dendritic cell)
plasmacytoid dendritic cell cytokine production SubClassOf process has causal agent some plasmacytoid dendritic cell

Added

plasmacytoid dendritic cell cytokine production EquivalentTo cytokine production and (occurs in some plasmacytoid dendritic cell)
plasmacytoid dendritic cell cytokine production SubClassOf occurs in some plasmacytoid dendritic cell

plasmodesma organization `http://purl.obolibrary.org/obo/GO_0009663`

Added

plasmodesma organization never in taxon Fungi
plasmodesma organization SubClassOf not (in taxon some Fungi)

positive regulation of ‘de novo’ NAD biosynthetic process from L-tryptophan `http://purl.obolibrary.org/obo/GO_1905014`

Added

positive regulation of ERAD pathway `http://purl.obolibrary.org/obo/GO_1904294`

Removed

positive regulation of ERAD pathway SubClassOf positive regulation of response to endoplasmic reticulum stress

positive regulation of cardiac endothelial to mesenchymal transition `http://purl.obolibrary.org/obo/GO_0062000`

Removed

positive regulation of cardiac endothelial to mesenchymal transition definition “Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal trnasition.”
- has cross-reference “GOC:BHF_miRNA”
- has cross-reference “PMID:26857067”
- has cross-reference “GOC:rph”
- has cross-reference “GOC:BHF”

Added

positive regulation of cardiac endothelial to mesenchymal transition definition “Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal transition.”
- has cross-reference “GOC:BHF_miRNA”
- has cross-reference “PMID:26857067”
- has cross-reference “GOC:rph”
- has cross-reference “GOC:BHF”

positive regulation of cristae formation `http://purl.obolibrary.org/obo/GO_1903852`

Removed

positive regulation of cristae formation SubClassOf positive regulation of organelle organization

Added

positive regulation of cristae formation SubClassOf positive regulation of cellular component organization

positive regulation of glycolysis `http://purl.obolibrary.org/obo/GO_0045821`

Removed

positive regulation of glycolysis label “positive regulation of glycolytic process”

Added

positive regulation of glycolysis has exact synonym “positive regulation of glycolytic process”
positive regulation of glycolysis label “positive regulation of glycolysis”

positive regulation of protein processing in phagocytic vesicle `http://purl.obolibrary.org/obo/GO_1903923`

Added

positive regulation of protein processing in phagocytic vesicle never in taxon Fungi
positive regulation of protein processing in phagocytic vesicle SubClassOf not (in taxon some Fungi)

positive regulation of sulfate assimilation `http://purl.obolibrary.org/obo/GO_1900059`

Removed

positive regulation of sulfate assimilation SubClassOf positive regulation of metabolic process

Added

positive regulation of sulfate assimilation SubClassOf positive regulation of small molecule metabolic process

positive regulation of tight junction disassembly `http://purl.obolibrary.org/obo/GO_1905075`

Added

positive regulation of tight junction disassembly never in taxon Fungi
positive regulation of tight junction disassembly SubClassOf not (in taxon some Fungi)

posterior abdomen determination `http://purl.obolibrary.org/obo/GO_0007359`

Removed

posterior abdomen determination definition “The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”
- has cross-reference “GOC:isa_complete”
- has cross-reference “GOC:dph”

Added

posterior abdomen determination term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
posterior abdomen determination definition “The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “GOC:isa_complete”
- has cross-reference “GOC:dph”

posterior compartment specification `http://purl.obolibrary.org/obo/GO_0007388`

Removed

posterior compartment specification definition “The process involved in the specification of cell identity in the posterior compartments of the segmented embryo.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

posterior compartment specification term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
posterior compartment specification definition “The process involved in the specification of cell identity in the posterior compartments of the segmented embryo.”
- has cross-reference “ISBN:0879694238”

postsynaptic early endosome `http://purl.obolibrary.org/obo/GO_0098842`

Removed

postsynaptic early endosome definition “An early endosome of the postsynapse. It acts as the major sorting station on the endocytic pathway, targeting neurotransmitter receptors for degregation or recycling.”
- has cross-reference “PMID:24727350”
- has cross-reference “PMID:20820847”
- has cross-reference “PMID:19603039”

Added

postsynaptic early endosome definition “An early endosome of the postsynapse. It acts as the major sorting station on the endocytic pathway, targeting neurotransmitter receptors for degradation or recycling.”
- has cross-reference “PMID:24727350”
- has cross-reference “PMID:20820847”
- has cross-reference “PMID:19603039”

pre-B cell receptor expression `http://purl.obolibrary.org/obo/GO_0002330`

Removed

pre-B cell receptor expression definition “The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, starting with the recombination of an immunuglobulin heavy chain locus, including expression of the surrogate light chain, the association of the surrogate light chain with the heavy chain, and expression of the complete pre-B cell receptor on the cell surface. pre-B cell receptor expression is a key checkpoint in the transition of pro-B cell to pre-B cell.”
- has cross-reference “PMID:22949502”
- has cross-reference “PMID:15263090”
- has cross-reference “PMID:9834086”
- has cross-reference “GOC:add”
- has cross-reference “GOC:jal”

Added

pre-B cell receptor expression definition “The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, starting with the recombination of an immunoglobulin heavy chain locus, including expression of the surrogate light chain, the association of the surrogate light chain with the heavy chain, and expression of the complete pre-B cell receptor on the cell surface. pre-B cell receptor expression is a key checkpoint in the transition of pro-B cell to pre-B cell.”
- has cross-reference “PMID:22949502”
- has cross-reference “PMID:15263090”
- has cross-reference “PMID:9834086”
- has cross-reference “GOC:add”
- has cross-reference “GOC:jal”

proteasomal degradation of multi-protein complex orphan subunits `http://purl.obolibrary.org/obo/GO_7770117`

Added

Class: proteasomal degradation of multi-protein complex orphan subunits
proteasomal degradation of multi-protein complex orphan subunits term tracker item “https://github.com/geneontology/go-ontology/issues/32274”^^anyURI
proteasomal degradation of multi-protein complex orphan subunits created by “ai4c-agent”
proteasomal degradation of multi-protein complex orphan subunits creation date “2026-08-27T23:33:52Z”
proteasomal degradation of multi-protein complex orphan subunits has_broad_synonym “degradation of orphan subunits of multi-protein complexes”
proteasomal degradation of multi-protein complex orphan subunits has_broad_synonym “orphan subunit degradation”
proteasomal degradation of multi-protein complex orphan subunits has_obo_namespace “biological_process”
proteasomal degradation of multi-protein complex orphan subunits id “GO:7770117”
proteasomal degradation of multi-protein complex orphan subunits definition “A protein quality control pathway that results in the ubiquitin-dependent, proteasome-mediated breakdown of orphan subunits of a multi-protein complex (including complexes that also contain non-protein components, such as the ribosome), i.e. subunits that have failed to assemble into their cognate complex, for example as a result of imbalanced subunit synthesis. This process eliminates unassembled subunits and thereby maintains protein complex stoichiometry.”
- has cross-reference “PMID:37480851”
- has cross-reference “PMID:35316660”
- has cross-reference “PMID:28774922”
proteasomal degradation of multi-protein complex orphan subunits label “proteasomal degradation of multi-protein complex orphan subunits”
proteasomal degradation of multi-protein complex orphan subunits SubClassOf protein quality control
proteasomal degradation of multi-protein complex orphan subunits SubClassOf proteasome-mediated ubiquitin-dependent protein catabolic process

proteasome substrate carrier activity `http://purl.obolibrary.org/obo/GO_0170082`

Added

Class: proteasome substrate carrier activity
proteasome substrate carrier activity term tracker item “https://github.com/geneontology/go-ontology/issues/32506”^^anyURI
proteasome substrate carrier activity created by “ew”
proteasome substrate carrier activity creation date “2026-08-25T15:54:46Z”
proteasome substrate carrier activity has_broad_synonym “ubiquitin receptor”
proteasome substrate carrier activity has exact synonym “proteasome substrate carrier”
proteasome substrate carrier activity has_obo_namespace “molecular_function”
proteasome substrate carrier activity id “GO:0170082”
proteasome substrate carrier activity definition “A protein carrier activity that recognizes and binds a polyubiquitinated substrate, usually via a UBA or similar ubiquitin-binding domain, and delivers it to the 26S proteasome by docking onto the 19S regulatory particle and releasing the substrate.”
- has cross-reference “PMID:33211406”
proteasome substrate carrier activity label “proteasome substrate carrier activity”
proteasome substrate carrier activity SubClassOf protein carrier activity
proteasome substrate carrier activity SubClassOf has part some polyubiquitin modification-dependent protein binding
proteasome substrate carrier activity SubClassOf has part some proteasome binding

protein carrier activity `http://purl.obolibrary.org/obo/GO_0140597`

Added

protein carrier activity conformsTo molecular_carrier_activity.yaml

protein insertion into mitochondrial membrane `http://purl.obolibrary.org/obo/GO_0051204`

Removed

protein insertion into mitochondrial membrane SubClassOf establishment of localization in cell

protein lipoylation `http://purl.obolibrary.org/obo/GO_0009249`

Removed

protein lipoylation definition “The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine.”
- has cross-reference “RESID:AA0118”

Added

protein lipoylation term tracker item “https://github.com/geneontology/go-ontology/issues/32418”^^anyURI
protein lipoylation has narrow synonym “lipoate biosynthesis”
protein lipoylation has narrow synonym “lipoate biosynthetic process”
protein lipoylation has narrow synonym “lipoic acid biosynthetic process”
protein lipoylation definition “The chemical reactions and pathways resulting in the attachment of a lipoyl group to a lipoyl carrier protein, either by de novo assembly on the carrier protein via transfer of an octanoyl group followed by sulfur insertion, or by ligation of exogenous lipoate.”
- has cross-reference “PMID:29987032”
- has cross-reference “RESID:AA0118”
protein lipoylation SubClassOf lipoate metabolic process

protein processing in phagocytic vesicle `http://purl.obolibrary.org/obo/GO_1900756`

Added

protein processing in phagocytic vesicle term tracker item “https://github.com/geneontology/go-ontology/issues/32152”^^anyURI
protein processing in phagocytic vesicle never in taxon Fungi
protein processing in phagocytic vesicle SubClassOf not (in taxon some Fungi)
protein processing in phagocytic vesicle SubClassOf part of some phagocytosis

protein quality control `http://purl.obolibrary.org/obo/GO_0006515`

Removed

protein quality control has_broad_synonym “protein quality control by the ubiquitin-proteasome system”
protein quality control has exact synonym “degradation of misfolded or incompletely synthesized proteins”
protein quality control has exact synonym “misfolded or incompletely synthesized protein breakdown”
protein quality control has exact synonym “misfolded or incompletely synthesized protein catabolic process”
protein quality control has exact synonym “misfolded or incompletely synthesized protein catabolism”
protein quality control has exact synonym “misfolded or incompletely synthesized protein degradation”
protein quality control has exact synonym “protein quality control (PQC)”
protein quality control definition “The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.”
- has cross-reference “GOC:jl”
protein quality control label “protein quality control for misfolded or incompletely synthesized proteins”
protein quality control SubClassOf protein catabolic process

Added

protein quality control term tracker item “https://github.com/geneontology/go-ontology/issues/32274”^^anyURI
protein quality control term tracker item “https://github.com/geneontology/go-ontology/issues/32442”^^anyURI
protein quality control term tracker item “https://github.com/geneontology/go-ontology/issues/32546”^^anyURI
protein quality control has exact synonym “PQC”
protein quality control has narrow synonym “degradation of misfolded or incompletely synthesized proteins”
protein quality control has narrow synonym “misfolded or incompletely synthesized protein breakdown”
protein quality control has narrow synonym “misfolded or incompletely synthesized protein catabolic process”
protein quality control has narrow synonym “misfolded or incompletely synthesized protein catabolism”
protein quality control has narrow synonym “misfolded or incompletely synthesized protein degradation”
protein quality control has narrow synonym “protein quality control by the ubiquitin-proteasome system”
protein quality control has narrow synonym “protein quality control for misfolded or incompletely synthesized proteins”
protein quality control definition “A cellular process that monitors the folding, integrity, and assembly state of proteins and acts on those recognized as aberrant, including misfolded, damaged, dysfunctional, or incompletely synthesized proteins, and orphan subunits that fail to assemble into their cognate protein complex, by refolding, stabilizing, sequestering, retaining, or degrading them.”
- has cross-reference “PMID:32075773”
- has cross-reference “PMID:35316660”
- has cross-reference “PMID:30075143”
- has cross-reference “PMID:21746797”
protein quality control label “protein quality control”
protein quality control SubClassOf cellular process

protein secretion by platelet `http://purl.obolibrary.org/obo/GO_0070560`

Removed

protein secretion by platelet EquivalentTo protein secretion and (process has causal agent some platelet)
protein secretion by platelet SubClassOf process has causal agent some platelet

Added

protein secretion by platelet EquivalentTo protein secretion and (occurs in some platelet)
protein secretion by platelet SubClassOf occurs in some platelet

protein-N(PI)-phosphohistidine-carbohydrate phosphotransferase activity `http://purl.obolibrary.org/obo/GO_0008982`

Removed

protein-N(PI)-phosphohistidine-carbohydrate phosphotransferase activity SubClassOf active transmembrane transporter activity

Added

protein-N(PI)-phosphohistidine-carbohydrate phosphotransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/27496”^^anyURI
protein-N(PI)-phosphohistidine-carbohydrate phosphotransferase activity SubClassOf group translocator activity

protein-containing complex `http://purl.obolibrary.org/obo/GO_0032991`

Added

protein-containing complex definition “A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.”

protein-exporting ATPase activity `http://purl.obolibrary.org/obo/GO_0008564`

Removed

protein-exporting ATPase activity definition “Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) = ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.”
- has cross-reference “EC:7.4.2.8”
- has cross-reference “PMID:30346996”

Added

protein-exporting ATPase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32395”^^anyURI
protein-exporting ATPase activity definition “Enables the transfer of a protein from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) = ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.”
- has cross-reference “EC:7.4.2.8”
- has cross-reference “PMID:30346996”

protein-phosphatidylethanolamine deconjugating activity `http://purl.obolibrary.org/obo/GO_0019786`

Removed

protein-phosphatidylethanolamine deconjugating activity has exact synonym “Atg8-specific protease activity”
protein-phosphatidylethanolamine deconjugating activity has_related_synonym “APG8-PE hydrolase”
protein-phosphatidylethanolamine deconjugating activity definition “Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue.”
- has cross-reference “PMID:2882172”
- has cross-reference “PMID:28330855”
- has cross-reference “PMID:22652539”
- has cross-reference “PMID:28901328”
- has cross-reference “PMID:22240591”
protein-phosphatidylethanolamine deconjugating activity label “protein-phosphatidylethanolamide deconjugating activity”

Added

protein-phosphatidylethanolamine deconjugating activity term tracker item “https://github.com/geneontology/go-ontology/issues/32575”^^anyURI
protein-phosphatidylethanolamine deconjugating activity has cross-reference “RHEA:67548”
protein-phosphatidylethanolamine deconjugating activity has narrow synonym “APG8-PE hydrolase”
protein-phosphatidylethanolamine deconjugating activity has narrow synonym “Atg8-specific protease activity”
protein-phosphatidylethanolamine deconjugating activity exactMatch 67548
protein-phosphatidylethanolamine deconjugating activity definition “Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamine via its terminal glycine residue.”
- has cross-reference “PMID:28330855”
- has cross-reference “PMID:22652539”
- has cross-reference “PMID:28821724”
- has cross-reference “PMID:28901328”
- has cross-reference “PMID:22240591”
- has cross-reference “RHEA:67548”
protein-phosphatidylethanolamine deconjugating activity label “protein-phosphatidylethanolamine deconjugating activity”

protein-phosphocysteine-sugar phosphotransferase activity `http://purl.obolibrary.org/obo/GO_0090563`

Removed

protein-phosphocysteine-sugar phosphotransferase activity SubClassOf active transmembrane transporter activity

Added

protein-phosphocysteine-sugar phosphotransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/27496”^^anyURI
protein-phosphocysteine-sugar phosphotransferase activity SubClassOf group translocator activity

protocatechuate 3,4-dioxygenase complex `http://purl.obolibrary.org/obo/GO_7770085`

Added

protocatechuate 3,4-dioxygenase complex conformsTo protein_complex_by_activity.yaml

pteridine reductase activity `http://purl.obolibrary.org/obo/GO_0047040`

Removed

pteridine reductase activity has narrow synonym “pteridine reductase 1 activity”
- has cross-reference “EC:1.5.1.33e”
pteridine reductase activity has narrow synonym “ptr1 activity”
- has cross-reference “EC:1.5.1.33e”

Added

pteridine reductase activity has narrow synonym “pteridine reductase 1 activity”
- has cross-reference “EC:1.5.1.33”
pteridine reductase activity has narrow synonym “ptr1 activity”
- has cross-reference “EC:1.5.1.33”

purine-containing compound catabolic process `http://purl.obolibrary.org/obo/GO_0072523`

Removed

purine-containing compound catabolic process SubClassOf catabolic process

Added

purine-containing compound catabolic process SubClassOf nucleobase-containing small molecule catabolic process

pyridoxal 5’-phosphate synthase (glutamine hydrolyzing) activity `http://purl.obolibrary.org/obo/GO_0036381`

Removed

pyridoxal 5’-phosphate synthase (glutamine hydrolyzing) activity has_related_synonym “pyridoxal 5’-phosphate synthase (glutamine hydrolyzing) activity”
- has cross-reference “EC:4.3.3.6”
pyridoxal 5’-phosphate synthase (glutamine hydrolyzing) activity label “pyridoxal 5’-phosphate synthase (glutamine hydrolysing) activity”

Added

pyridoxal 5’-phosphate synthase (glutamine hydrolyzing) activity has_related_synonym “pyridoxal 5’-phosphate synthase (glutamine hydrolysing) activity”
- has cross-reference “EC:4.3.3.6”
pyridoxal 5’-phosphate synthase (glutamine hydrolyzing) activity label “pyridoxal 5’-phosphate synthase (glutamine hydrolyzing) activity”

rRNA (adenine-N6-)-methyltransferase activity `http://purl.obolibrary.org/obo/GO_0008988`

Removed

rRNA (adenine-N6-)-methyltransferase activity SubClassOf N-methyltransferase activity

Added

rRNA (adenine-N6-)-methyltransferase activity SubClassOf RNA (adenine-N6)-methyltransferase activity

receptor diffusion trapping `http://purl.obolibrary.org/obo/GO_0098953`

Removed

receptor diffusion trapping definition “The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region. This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix.”
- has cross-reference “PMID:18832033”

Added

receptor diffusion trapping definition “The process by which a membrane receptor, diffusing freely within the plasma membrane, becomes trapped in some plasma membrane region. This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix.”
- has cross-reference “PMID:18832033”

regulation of ‘de novo’ NAD biosynthetic process from L-tryptophan `http://purl.obolibrary.org/obo/GO_1905012`

Added

regulation of ERAD pathway `http://purl.obolibrary.org/obo/GO_1904292`

Removed

regulation of ERAD pathway SubClassOf regulation of response to endoplasmic reticulum stress

regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process `http://purl.obolibrary.org/obo/GO_0062025`

Removed

regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process definition “Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.”
- has cross-reference “PMID:28007894”

Added

regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process definition “Any process that modulates the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.”
- has cross-reference “PMID:28007894”

regulation of axon extension `http://purl.obolibrary.org/obo/GO_0030516`

Removed

regulation of axon extension SubClassOf regulation of extent of cell growth

Added

regulation of axon extension term tracker item “https://github.com/geneontology/go-ontology/issues/19737”^^anyURI
regulation of axon extension SubClassOf regulation of cell growth

regulation of collateral sprouting `http://purl.obolibrary.org/obo/GO_0048670`

Removed

regulation of collateral sprouting SubClassOf regulation of extent of cell growth

Added

regulation of collateral sprouting term tracker item “https://github.com/geneontology/go-ontology/issues/19737”^^anyURI
regulation of collateral sprouting SubClassOf regulation of cell growth

regulation of cristae formation `http://purl.obolibrary.org/obo/GO_1903850`

Removed

regulation of cristae formation SubClassOf regulation of mitochondrion organization

Added

regulation of cristae formation SubClassOf regulation of cellular component organization

regulation of direction of cell growth `http://purl.obolibrary.org/obo/GO_0061389`

Removed

regulation of direction of cell growth definition “Any process that modulates the direction of cell growth.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:vw”

Added

regulation of direction of cell growth term tracker item “https://github.com/geneontology/go-ontology/issues/19737”^^anyURI
regulation of direction of cell growth definition “Any process that modulates where in a cell additional mass is added during cell growth.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:vw”

regulation of extent of cell growth `http://purl.obolibrary.org/obo/GO_0061387`

Removed

regulation of extent of cell growth definition “Any process that modulates the extent of cell growth.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:vw”

Added

regulation of extent of cell growth term tracker item “https://github.com/geneontology/go-ontology/issues/19737”^^anyURI
regulation of extent of cell growth definition “Any process that modulates how much additional mass a cell adds during cell growth before growth ceases.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:vw”

regulation of glycolysis `http://purl.obolibrary.org/obo/GO_0006110`

Removed

regulation of glycolysis label “regulation of glycolytic process”

Added

regulation of glycolysis term tracker item “https://github.com/geneontology/go-ontology/issues/32471”^^anyURI
regulation of glycolysis has exact synonym “regulation of glycolytic process”
regulation of glycolysis label “regulation of glycolysis”

regulation of mitochondrial respiratory chain complex I assembly `http://purl.obolibrary.org/obo/GO_7770119`

Added

Class: regulation of mitochondrial respiratory chain complex I assembly
regulation of mitochondrial respiratory chain complex I assembly term tracker item “https://github.com/geneontology/go-ontology/issues/32577”^^anyURI
regulation of mitochondrial respiratory chain complex I assembly never in taxon Schizosaccharomyces
regulation of mitochondrial respiratory chain complex I assembly never in taxon Saccharomyces
regulation of mitochondrial respiratory chain complex I assembly created by “ai4c-agent”
regulation of mitochondrial respiratory chain complex I assembly creation date “2026-09-11T00:23:26Z”
regulation of mitochondrial respiratory chain complex I assembly has_obo_namespace “biological_process”
regulation of mitochondrial respiratory chain complex I assembly id “GO:7770119”
regulation of mitochondrial respiratory chain complex I assembly definition “Any process that modulates the frequency, rate or extent of mitochondrial respiratory chain complex I assembly.”
- has cross-reference “PMID:42361792”
regulation of mitochondrial respiratory chain complex I assembly label “regulation of mitochondrial respiratory chain complex I assembly”
regulation of mitochondrial respiratory chain complex I assembly EquivalentTo biological regulation and (regulates some mitochondrial respiratory chain complex I assembly)
regulation of mitochondrial respiratory chain complex I assembly SubClassOf regulation of protein-containing complex assembly
regulation of mitochondrial respiratory chain complex I assembly SubClassOf not (in taxon some Schizosaccharomyces)
regulation of mitochondrial respiratory chain complex I assembly SubClassOf not (in taxon some Saccharomyces)
regulation of mitochondrial respiratory chain complex I assembly SubClassOf regulates some mitochondrial respiratory chain complex I assembly

regulation of protein processing in phagocytic vesicle `http://purl.obolibrary.org/obo/GO_1903921`

Added

regulation of protein processing in phagocytic vesicle never in taxon Fungi
regulation of protein processing in phagocytic vesicle SubClassOf not (in taxon some Fungi)

regulation of rate of cell growth `http://purl.obolibrary.org/obo/GO_0061388`

Removed

regulation of rate of cell growth definition “Any process that modulates the rate of cell growth.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:vw”

Added

regulation of rate of cell growth term tracker item “https://github.com/geneontology/go-ontology/issues/19737”^^anyURI
regulation of rate of cell growth definition “Any process that modulates how fast a cell adds additional mass during cell growth.”
- has cross-reference “GOC:mah”
- has cross-reference “GOC:vw”

regulation of sprouting of injured axon `http://purl.obolibrary.org/obo/GO_0048686`

Removed

regulation of sprouting of injured axon SubClassOf regulation of extent of cell growth

Added

regulation of sprouting of injured axon term tracker item “https://github.com/geneontology/go-ontology/issues/19737”^^anyURI
regulation of sprouting of injured axon SubClassOf regulation of cell growth

regulation of sulfate assimilation `http://purl.obolibrary.org/obo/GO_1900058`

Added

regulation of sulfate assimilation SubClassOf regulation of small molecule metabolic process

regulation of tight junction disassembly `http://purl.obolibrary.org/obo/GO_1905073`

Added

regulation of tight junction disassembly never in taxon Fungi
regulation of tight junction disassembly SubClassOf not (in taxon some Fungi)

regulation of transcription by RNA polymerase III `http://purl.obolibrary.org/obo/GO_0006359`

Removed

regulation of transcription by RNA polymerase III definition “Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III.”
- has cross-reference “GOC:curators”

Added

regulation of transcription by RNA polymerase III definition “Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase III.”
- has cross-reference “GOC:curators”

regulatory ncRNA-mediated heterochromatin formation `http://purl.obolibrary.org/obo/GO_0031048`

Removed

regulatory ncRNA-mediated heterochromatin formation definition “A heterochromatin formation-based gene silencing process mediated by a regulatory non-coding RNA molecule that occur before the beginning of trancription.”
- has cross-reference “PMID:21420348”
- has cross-reference “PMID:19239886”

Added

regulatory ncRNA-mediated heterochromatin formation definition “A heterochromatin formation-based gene silencing process mediated by a regulatory non-coding RNA molecule that occurs before the beginning of transcription.”
- has cross-reference “PMID:21420348”
- has cross-reference “PMID:19239886”

replicative senescence `http://purl.obolibrary.org/obo/GO_0090399`

Removed

replicative senescence definition “The process by which normal somatic cells reach an irreversible stage of cell cycle arrest following multiple rounds of replication; this end stage is associated with marked changes in gene expression and function. This is a natural barrier to unlimited proliferation of somatic cells, and is believed to be contolled by telomere shortening.”
- has cross-reference “PMID:23061726”
- has cross-reference “PMID:17014937”

Added

replicative senescence definition “The process by which normal somatic cells reach an irreversible stage of cell cycle arrest following multiple rounds of replication; this end stage is associated with marked changes in gene expression and function. This is a natural barrier to unlimited proliferation of somatic cells, and is believed to be controlled by telomere shortening.”
- has cross-reference “PMID:23061726”
- has cross-reference “PMID:17014937”

rescue of stalled mitochondrial ribosome `http://purl.obolibrary.org/obo/GO_7770016`

Removed

rescue of stalled mitochondrial ribosome SubClassOf rescue of stalled cytosolic ribosome

Added

rescue of stalled mitochondrial ribosome term tracker item “https://github.com/geneontology/go-ontology/issues/26238”^^anyURI
rescue of stalled mitochondrial ribosome SubClassOf ribosome disassembly

respiratory burst after phagocytosis `http://purl.obolibrary.org/obo/GO_0045728`

Added

respiratory burst after phagocytosis term tracker item “https://github.com/geneontology/go-ontology/issues/32152”^^anyURI
respiratory burst after phagocytosis SubClassOf preceded by some phagocytosis

response to interleukin-5 `http://purl.obolibrary.org/obo/GO_7770102`

Added

Class: response to interleukin-5
response to interleukin-5 term tracker item “https://github.com/geneontology/go-ontology/issues/32411”^^anyURI
response to interleukin-5 created by “ai4c-agent”
response to interleukin-5 creation date “2026-08-04T23:16:15Z”
response to interleukin-5 has exact synonym “response to IL-5”
response to interleukin-5 has_obo_namespace “biological_process”
response to interleukin-5 id “GO:7770102”
response to interleukin-5 definition “Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-5 stimulus.”
- has cross-reference “PMID:41207640”
response to interleukin-5 label “response to interleukin-5”
response to interleukin-5 SubClassOf response to cytokine

response to mitochondrial depolarization `http://purl.obolibrary.org/obo/GO_0098780`

Removed

response to mitochondrial depolarization label “response to mitochondrial depolarisation”

Added

response to mitochondrial depolarization label “response to mitochondrial depolarization”

retrograde trans-synaptic signaling by endocannabinoid `http://purl.obolibrary.org/obo/GO_0098921`

Removed

retrograde trans-synaptic signaling by endocannabinoid EquivalentTo trans-synaptic signaling and (has start location some postsynapse) and (has end location some presynapse) and (process has causal agent some cannabinoid)

Added

retrograde trans-synaptic signaling by endocannabinoid term tracker item “https://github.com/geneontology/go-ontology/issues/20574”^^anyURI
retrograde trans-synaptic signaling by endocannabinoid EquivalentTo trans-synaptic signaling and (has start location some postsynapse) and (has end location some presynapse) and (process has causal agent some endocannabinoid)

retrotransposition `http://purl.obolibrary.org/obo/GO_0032197`

Removed

retrotransposition definition “A type of transposition in which a transposable element (transposon) copies and pastes itself into a different genomic location by transcription and convertsion of the transcribed RNA back into DNA through reverse transcription.”
- has cross-reference “PMID:30416149”
- has cross-reference “PMID:30958115”
- has cross-reference “ISBN:1555812090”
- has cross-reference “PMID:32588192”
- has cross-reference “PMID:26912865”

Added

retrotransposition definition “A type of transposition in which a transposable element (transposon) copies and pastes itself into a different genomic location by transcription and conversion of the transcribed RNA back into DNA through reverse transcription.”
- has cross-reference “PMID:30416149”
- has cross-reference “PMID:30958115”
- has cross-reference “ISBN:1555812090”
- has cross-reference “PMID:32588192”
- has cross-reference “PMID:26912865”

riboflavin kinase activity `http://purl.obolibrary.org/obo/GO_0008531`

Removed

riboflavin kinase activity definition “Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H+.”
- has cross-reference “EC:2.7.1.26”
- has cross-reference “RHEA:14357”

Added

riboflavin kinase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32345”^^anyURI
riboflavin kinase activity definition “Catalysis of the reaction: riboflavin + ATP = FMN + ADP + H+.”
- has cross-reference “RHEA:14357”

ribosome-associated chaperone complex `http://purl.obolibrary.org/obo/GO_0170081`

Added

Class: ribosome-associated chaperone complex
ribosome-associated chaperone complex term tracker item “https://github.com/geneontology/go-ontology/issues/32185”^^anyURI
ribosome-associated chaperone complex created by “ew”
ribosome-associated chaperone complex creation date “2026-08-20T20:04:20Z”
ribosome-associated chaperone complex has narrow synonym “MPP11/Hsp70L1 complex”
ribosome-associated chaperone complex has narrow synonym “Zuo1/Ssz1 complex”
ribosome-associated chaperone complex has narrow synonym “zuotin complex”
ribosome-associated chaperone complex has_obo_namespace “cellular_component”
ribosome-associated chaperone complex has_related_synonym “RAC”
ribosome-associated chaperone complex has_related_synonym “ribosome-associated complex”
ribosome-associated chaperone complex id “GO:0170081”
ribosome-associated chaperone complex definition “A conserved heterodimeric co-chaperone complex, composed of a J-domain (Hsp40-family) protein and an atypical Hsp70-family protein, that associates with the ribosome and acts on nascent polypeptide chains as they emerge from the exit tunnel to enable their co-translational folding. In Saccharomyces cerevisiae, the complex consists of the J-domain protein Zuo1 (Hsp40) and the non-canonical Hsp70 homolog Ssz1. The mammalian ortholog comprises ZRF1/MPP11 (Hsp40) and HSPA14/HSP70L1 (Hsp70).”
- has cross-reference “PMID:11274393”
- has cross-reference “PMID:16002468”
ribosome-associated chaperone complex comment “Note that this term does not cover the nascent polypeptide-associated complex (GO:0005854), a distinct ribosome-associated heterodimer that acts in nascent chain sorting rather than folding.”
ribosome-associated chaperone complex label “ribosome-associated chaperone complex”
ribosome-associated chaperone complex SubClassOf protein folding chaperone complex
ribosome-associated chaperone complex SubClassOf part of some cytosol
ribosome-associated chaperone complex SubClassOf in taxon some cellular organisms
ribosome-associated chaperone complex SubClassOf capable of part of some ‘de novo’ cotranslational protein folding

ribosome-associated quality control `http://purl.obolibrary.org/obo/GO_7770112`

Added

Class: ribosome-associated quality control
ribosome-associated quality control term tracker item “https://github.com/geneontology/go-ontology/issues/18610”^^anyURI
ribosome-associated quality control term tracker item “https://github.com/geneontology/go-ontology/issues/26238”^^anyURI
ribosome-associated quality control term tracker item “https://github.com/geneontology/go-ontology/issues/32546”^^anyURI
ribosome-associated quality control created by “ai4c-agent”
ribosome-associated quality control creation date “2026-08-18T05:06:46Z”
ribosome-associated quality control has exact synonym “RQC”
ribosome-associated quality control has exact synonym “ribosome quality control”
ribosome-associated quality control has_obo_namespace “biological_process”
ribosome-associated quality control id “GO:7770112”
ribosome-associated quality control has exact synonym “ribosome-associated protein quality control”
- has cross-reference “PMID:26733220”
ribosome-associated quality control definition “A protein quality control pathway that acts on ribosomes stalled during translation to target the incomplete nascent polypeptide chain for degradation.”
- has cross-reference “PMID:34233554”
- has cross-reference “PMID:32569528”
- has cross-reference “PMID:35452614”
ribosome-associated quality control comment “The core RQC machinery (NEMF/Rqc2/RqcH and the associated untemplated C-terminal chain elongation) is conserved from bacteria to humans, so this term is not restricted to eukaryotes.”
ribosome-associated quality control label “ribosome-associated quality control”
ribosome-associated quality control SubClassOf protein quality control
ribosome-associated quality control SubClassOf ends with some protein catabolic process

ribosome-associated ubiquitin-dependent protein catabolic process `http://purl.obolibrary.org/obo/GO_1990116`

Added

ribosome-associated ubiquitin-dependent protein catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/26238”^^anyURI
ribosome-associated ubiquitin-dependent protein catabolic process SubClassOf part of some ribosome-associated quality control

ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity `http://purl.obolibrary.org/obo/GO_0046863`

Removed

ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity definition “Binds to and iincreases the activity of rubisco by the removal of otherwise inhibitory sugar phosphates: RuBP, and in some plants, 2-carboxyarabinitol 1-phosphate.”
- has cross-reference “PMID:2404515”
- has cross-reference “PMID:10430961”
- has cross-reference “PMID:10965036”

Added

ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity definition “Binds to and increases the activity of rubisco by the removal of otherwise inhibitory sugar phosphates: RuBP, and in some plants, 2-carboxyarabinitol 1-phosphate.”
- has cross-reference “PMID:2404515”
- has cross-reference “PMID:10430961”
- has cross-reference “PMID:10965036”

segment polarity determination `http://purl.obolibrary.org/obo/GO_0007367`

Removed

segment polarity determination definition “Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”
- has cross-reference “ISBN:0632030488”

Added

segment polarity determination term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
segment polarity determination definition “Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “ISBN:0632030488”

segment specification `http://purl.obolibrary.org/obo/GO_0007379`

Removed

segment specification definition “The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

segment specification term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
segment specification definition “The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.”
- has cross-reference “ISBN:0879694238”

serotonin secretion by basophil `http://purl.obolibrary.org/obo/GO_0002556`

Removed

serotonin secretion by basophil EquivalentTo serotonin secretion and (process has causal agent some basophil)
serotonin secretion by basophil SubClassOf process has causal agent some basophil

Added

serotonin secretion by basophil EquivalentTo serotonin secretion and (occurs in some basophil)
serotonin secretion by basophil SubClassOf occurs in some basophil

serotonin secretion by mast cell `http://purl.obolibrary.org/obo/GO_0002552`

Removed

serotonin secretion by mast cell EquivalentTo serotonin secretion and (process has causal agent some mast cell)
serotonin secretion by mast cell SubClassOf process has causal agent some mast cell

Added

serotonin secretion by mast cell EquivalentTo serotonin secretion and (occurs in some mast cell)
serotonin secretion by mast cell SubClassOf occurs in some mast cell

serotonin secretion by platelet `http://purl.obolibrary.org/obo/GO_0002554`

Removed

serotonin secretion by platelet EquivalentTo serotonin secretion and (process has causal agent some platelet)
serotonin secretion by platelet SubClassOf process has causal agent some platelet

Added

serotonin secretion by platelet EquivalentTo serotonin secretion and (occurs in some platelet)
serotonin secretion by platelet SubClassOf occurs in some platelet

serotonin-gated cation-selective signaling pathway `http://purl.obolibrary.org/obo/GO_0140227`

Removed

serotonin-gated cation-selective signaling pathway definition “The series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.”
- has cross-reference “PMID:27764665”
- has cross-reference “PMID:25392484”
- has cross-reference “GOC:bhm”

Added

serotonin-gated cation-selective signaling pathway definition “The series of molecular signals initiated by serotonin binding to a serotonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.”
- has cross-reference “PMID:27764665”
- has cross-reference “PMID:25392484”
- has cross-reference “GOC:bhm”

sex comb development `http://purl.obolibrary.org/obo/GO_0045498`

Removed

sex comb development definition “The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg.”
- has cross-reference “http://fly.ebi.ac.uk”

Added

sex comb development term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
sex comb development definition “The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg.”
- has cross-reference “FBbt:00004296”

snRNA 2,2,7-trimethylguanosine (TMG) capping `http://purl.obolibrary.org/obo/GO_1990273`

Removed

snRNA 2,2,7-trimethylguanosine (TMG) capping definition “The sequence of enzymatic reactions by which a 2,2,7-trimethylguanosine cap structure is added to the 5’ end of an snRNA. The snRNA capping process includes the formation of 7-methyl-G caps found on all RNA polymerase II transcripts, followed by hypermethylation at the 2’ position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. Note that the pol III transcribed U6 snRNA is also TMG capped.”
- has cross-reference “PMID:15590684”
- has cross-reference “GOC:vw”

Added

snRNA 2,2,7-trimethylguanosine (TMG) capping term tracker item “https://github.com/geneontology/go-ontology/issues/27628”^^anyURI
snRNA 2,2,7-trimethylguanosine (TMG) capping definition “The sequence of enzymatic reactions by which a 2,2,7-trimethylguanosine (TMG) cap structure is added to the 5’ end of an snRNA. The process begins with the formation of a 7-methylguanosine cap, as found on all RNA polymerase II transcripts, followed by dimethylation at the N2 position of the guanine base to convert the monomethylated cap to a 2,2,7-trimethylguanosine cap structure.”
- has cross-reference “PMID:15590684”
- has cross-reference “GOC:vw”
- has cross-reference “PMID:11142384”
snRNA 2,2,7-trimethylguanosine (TMG) capping comment “TMG capped snRNAs are RNA polymerase II transcripts. The RNA polymerase III transcribed U6 snRNA is not TMG capped; it carries a gamma-monomethyl phosphate cap added by the Bin3/MePCE family of methylphosphate capping enzymes (PMID:2229067, PMID:37403782). TMG capping of a Pol III transcript has been reported only for engineered U6 variants in which disruption of the 5’ stem-loop exposes the 5’-triphosphate to the normal methylguanosine capping machinery (PMID:11142384).”
snRNA 2,2,7-trimethylguanosine (TMG) capping SubClassOf has part some 7-methylguanosine RNA capping
snRNA 2,2,7-trimethylguanosine (TMG) capping SubClassOf has part some 7-methylguanosine cap hypermethylation

snoRNA 2,2,7-trimethylguanosine (TMG) capping `http://purl.obolibrary.org/obo/GO_0180031`

Removed

snoRNA 2,2,7-trimethylguanosine (TMG) capping definition “The sequence of enzymatic reactions by which a 2,2,7-trimethylguanosine cap structure is added to the 5’ end of an snoRNA. The snoRNA capping includes the formation of 7-methyl-G caps found on all RNA polymerase II transcripts, followed by hypermethylation at the 2’ position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. Note that the pol III transcribed snoRNAs are also TMG capped.”
- has cross-reference “PMID:15590684”
- has cross-reference “GOC:vw”

Added

snoRNA 2,2,7-trimethylguanosine (TMG) capping term tracker item “https://github.com/geneontology/go-ontology/issues/27628”^^anyURI
snoRNA 2,2,7-trimethylguanosine (TMG) capping definition “The sequence of enzymatic reactions by which a 2,2,7-trimethylguanosine (TMG) cap structure is added to the 5’ end of an snoRNA. The process begins with the formation of a 7-methylguanosine cap, as found on all RNA polymerase II transcripts, followed by dimethylation at the N2 position of the guanine base to convert the monomethylated cap to a 2,2,7-trimethylguanosine cap structure.”
- has cross-reference “PMID:11983179”
- has cross-reference “PMID:15590684”
- has cross-reference “GOC:vw”
snoRNA 2,2,7-trimethylguanosine (TMG) capping comment “TMG capped snoRNAs are RNA polymerase II transcripts. Where a snoRNA is transcribed by RNA polymerase III it is not TMG capped: plant U3 snoRNA, which is Pol III transcribed, carries a gamma-monomethyl phosphate cap, whereas the same snoRNA is TMG capped in the animals and fungi where it is Pol II transcribed (PMID:1618872).”
snoRNA 2,2,7-trimethylguanosine (TMG) capping SubClassOf has part some 7-methylguanosine RNA capping
snoRNA 2,2,7-trimethylguanosine (TMG) capping SubClassOf has part some 7-methylguanosine cap hypermethylation

sphingolipid floppase activity `http://purl.obolibrary.org/obo/GO_0046623`

Added

sphingolipid floppase activity conformsTo lipid_floppase_activity.yaml

sphingolipid intramembrane carrier activity `http://purl.obolibrary.org/obo/GO_0046624`

Added

sphingolipid intramembrane carrier activity conformsTo intramembrane_lipid_carrier_activity.yaml

sphingolipid transfer activity `http://purl.obolibrary.org/obo/GO_0120016`

Added

sphingolipid transfer activity conformsTo intermembrane_lipid_transfer_activity.yaml

sphingomyelin transfer activity `http://purl.obolibrary.org/obo/GO_0140338`

Added

sphingomyelin transfer activity conformsTo intermembrane_lipid_transfer_activity.yaml

spongiome `http://purl.obolibrary.org/obo/GO_0062160`

Removed

spongiome definition “A cellular anatomical entity which is a network of tubules and vessicles and is part of the contractile vacuole complex. It is involved in the discharge of water externally. One of its functions is osmoregulatory.”
- has cross-reference “PMID:23890380”

Added

spongiome definition “A cellular anatomical entity which is a network of tubules and vesicles and is part of the contractile vacuole complex. It is involved in the discharge of water externally. One of its functions is osmoregulatory.”
- has cross-reference “PMID:23890380”

sterol transfer activity `http://purl.obolibrary.org/obo/GO_0120015`

Added

sterol transfer activity conformsTo intermembrane_lipid_transfer_activity.yaml

subtelomeric heterochromatin formation `http://purl.obolibrary.org/obo/GO_0031509`

Removed

subtelomeric heterochromatin formation SubClassOf occurs in some chromosome, telomeric region

Added

subtelomeric heterochromatin formation term tracker item “https://github.com/geneontology/go-ontology/issues/32403”^^anyURI
subtelomeric heterochromatin formation EquivalentTo constitutive heterochromatin formation and (results in assembly of some subtelomeric heterochromatin)
subtelomeric heterochromatin formation SubClassOf results in assembly of some subtelomeric heterochromatin

sulfate assimilation `http://purl.obolibrary.org/obo/GO_0000103`

Added

sulfate assimilation term tracker item “https://github.com/geneontology/go-ontology/issues/32287”^^anyURI
sulfate assimilation term tracker item “https://github.com/geneontology/go-ontology/issues/32376”^^anyURI
sulfate assimilation SubClassOf small molecule metabolic process
sulfate assimilation SubClassOf nutrient assimilation

symbiont-mediated perturbation of host actin cytoskeleton via actin filament reorganization `http://purl.obolibrary.org/obo/GO_0141032`

Removed

symbiont-mediated perturbation of host actin cytoskeleton via actin filament reorganization definition “The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by reorganizing the actin filaments, in a way that keeps the total filementous actin remains approximately constant. The host is defined as the larger of the organisms involved in a symbiotic interaction.”
- has cross-reference “PMID:31130928”
- has cross-reference “PMID:22212282”

Added

symbiont-mediated perturbation of host actin cytoskeleton via actin filament reorganization definition “The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by reorganizing the actin filaments, in a way that keeps the total filamentous actin approximately constant. The host is defined as the larger of the organisms involved in a symbiotic interaction.”
- has cross-reference “PMID:31130928”
- has cross-reference “PMID:22212282”

symmetric synapse `http://purl.obolibrary.org/obo/GO_0032280`

Removed

symmetric synapse definition “A synapse that lacks an electron dense postsynaptic specialization. In vertebtrates, these occur primarily on dendrite shafts and neuronal cell bodies and involve persynapses containing clusters of predominantly flattened or elongated vesicles and are typically inhibitory.”
- has cross-reference “GOC:ef”
- has cross-reference “GOC:dgh”

Added

symmetric synapse definition “A synapse that lacks an electron dense postsynaptic specialization. In vertebrates, these occur primarily on dendrite shafts and neuronal cell bodies and involve presynapses containing clusters of predominantly flattened or elongated vesicles and are typically inhibitory.”
- has cross-reference “GOC:ef”
- has cross-reference “GOC:dgh”

tRNA aminoacylation for nonribosomal peptide biosynthetic process `http://purl.obolibrary.org/obo/GO_0043040`

Removed

tRNA aminoacylation for nonribosomal peptide biosynthetic process SubClassOf obsolete amino acid activation for nonribosomal peptide biosynthetic process

Added

tRNA aminoacylation for nonribosomal peptide biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/15375”^^anyURI
tRNA aminoacylation for nonribosomal peptide biosynthetic process SubClassOf part of some nonribosomal peptide biosynthetic process

tRNA aminoacylation for protein translation `http://purl.obolibrary.org/obo/GO_0006418`

Removed

tRNA aminoacylation for protein translation has narrow synonym “tRNA charging”

tRNA charging `http://purl.obolibrary.org/obo/GO_0043039`

Removed

tRNA charging has exact synonym “tRNA charging”
tRNA charging label “tRNA aminoacylation”
tRNA charging SubClassOf obsolete amino acid activation

Added

tRNA charging has exact synonym “aminoacyl tRNA synthesis”
tRNA charging has exact synonym “tRNA aminoacylation”
tRNA charging label “tRNA charging”

tRNA(Val) (adenine(37)-N6)-methyltransferase activity `http://purl.obolibrary.org/obo/GO_7770054`

Removed

tRNA(Val) (adenine(37)-N6)-methyltransferase activity SubClassOf N-methyltransferase activity

Added

tRNA(Val) (adenine(37)-N6)-methyltransferase activity SubClassOf RNA (adenine-N6)-methyltransferase activity

terminal region determination `http://purl.obolibrary.org/obo/GO_0007362`

Removed

terminal region determination definition “Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

terminal region determination term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
terminal region determination definition “Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products.”
- has cross-reference “ISBN:0879694238”

thioredoxin-dependent peroxiredoxin activity `http://purl.obolibrary.org/obo/GO_0140824`

Added

thioredoxin-dependent peroxiredoxin activity term tracker item “https://github.com/geneontology/go-ontology/issues/32388”^^anyURI
thioredoxin-dependent peroxiredoxin activity has cross-reference “MetaCyc:RXN0-267”
thioredoxin-dependent peroxiredoxin activity has cross-reference “RHEA:63528”
thioredoxin-dependent peroxiredoxin activity has exact synonym “TPx activity”
thioredoxin-dependent peroxiredoxin activity has exact synonym “TrxPx activity”
thioredoxin-dependent peroxiredoxin activity has exact synonym “thioredoxin peroxidase activity”
thioredoxin-dependent peroxiredoxin activity has_related_synonym “thiol peroxidase activity”
thioredoxin-dependent peroxiredoxin activity narrowMatch RXN0-267
thioredoxin-dependent peroxiredoxin activity narrowMatch 63528

thorax and anterior abdomen determination `http://purl.obolibrary.org/obo/GO_0007356`

Removed

thorax and anterior abdomen determination definition “Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

thorax and anterior abdomen determination term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
thorax and anterior abdomen determination definition “Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product.”
- has cross-reference “ISBN:0879694238”

tight junction disassembly `http://purl.obolibrary.org/obo/GO_1905071`

Added

tight junction disassembly never in taxon Fungi
tight junction disassembly SubClassOf not (in taxon some Fungi)

tight junction organization `http://purl.obolibrary.org/obo/GO_0120193`

Added

tight junction organization never in taxon Fungi
tight junction organization SubClassOf not (in taxon some Fungi)

trans-synaptic signaling by endocannabinoid `http://purl.obolibrary.org/obo/GO_0099542`

Removed

trans-synaptic signaling by endocannabinoid EquivalentTo trans-synaptic signaling and (process has causal agent some cannabinoid)
trans-synaptic signaling by endocannabinoid SubClassOf process has causal agent some cannabinoid

Added

trans-synaptic signaling by endocannabinoid term tracker item “https://github.com/geneontology/go-ontology/issues/20574”^^anyURI
trans-synaptic signaling by endocannabinoid EquivalentTo trans-synaptic signaling and (process has causal agent some endocannabinoid)
trans-synaptic signaling by endocannabinoid SubClassOf process has causal agent some endocannabinoid

trans-synaptic signaling by endocannabinoid, modulating synaptic transmission `http://purl.obolibrary.org/obo/GO_0099553`

Removed

trans-synaptic signaling by endocannabinoid, modulating synaptic transmission EquivalentTo trans-synaptic signaling and (regulates some chemical synaptic transmission) and (process has causal agent some cannabinoid)

Added

trans-synaptic signaling by endocannabinoid, modulating synaptic transmission term tracker item “https://github.com/geneontology/go-ontology/issues/20574”^^anyURI
trans-synaptic signaling by endocannabinoid, modulating synaptic transmission EquivalentTo trans-synaptic signaling and (regulates some chemical synaptic transmission) and (process has causal agent some endocannabinoid)

transcription elongation by mitochondrial RNA polymerase `http://purl.obolibrary.org/obo/GO_0006392`

Removed

transcription elongation by mitochondrial RNA polymerase definition “The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase.”
- has cross-reference “GOC:txnOH”
- has cross-reference “GOC:mah”

Added

transcription elongation by mitochondrial RNA polymerase definition “The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitochondrial RNA polymerase.”
- has cross-reference “GOC:txnOH”
- has cross-reference “GOC:mah”

transporter activity `http://purl.obolibrary.org/obo/GO_0005215`

Removed

transporter activity definition “Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells.”
- has cross-reference “GOC:ai”
- has cross-reference “GOC:dgf”

Added

transporter activity definition “Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, across or in between cells.”
- has cross-reference “GOC:ai”
- has cross-reference “GOC:dgf”

tricellular tight junction disassembly `http://purl.obolibrary.org/obo/GO_1904275`

Added

tricellular tight junction disassembly never in taxon Fungi
tricellular tight junction disassembly SubClassOf not (in taxon some Fungi)

tricetin O-methyltransferase activity `http://purl.obolibrary.org/obo/GO_0102146`

Removed

tricetin O-methyltransferase activity label “tricetin O-methytransferase activity”

Added

tricetin O-methyltransferase activity label “tricetin O-methyltransferase activity”

triglyceride transfer activity `http://purl.obolibrary.org/obo/GO_0140344`

Added

triglyceride transfer activity conformsTo intermembrane_lipid_transfer_activity.yaml

tripartite regional subdivision `http://purl.obolibrary.org/obo/GO_0007351`

Removed

tripartite regional subdivision definition “Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”
- has cross-reference “GOC:isa_complete”
- has cross-reference “GOC:dph”

Added

tripartite regional subdivision term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
tripartite regional subdivision definition “Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “GOC:isa_complete”
- has cross-reference “GOC:dph”

type III site-specific deoxyribonuclease complex `http://purl.obolibrary.org/obo/GO_0019813`

Removed

type III site-specific deoxyribonuclease complex definition “A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.”
- has cross-reference “PMID:12654995”

Added

type III site-specific deoxyribonuclease complex definition “A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltransferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.”
- has cross-reference “PMID:12654995”

ubiquitin-dependent glycoprotein ERAD pathway `http://purl.obolibrary.org/obo/GO_0097466`

Removed

ubiquitin-dependent glycoprotein ERAD pathway SubClassOf response to glycoprotein

undecaprenol kinase activity `http://purl.obolibrary.org/obo/GO_0009038`

Removed

undecaprenol kinase activity definition “Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate.”
- has cross-reference “GOC:curators”

Added

undecaprenol kinase activity term tracker item “https://github.com/geneontology/go-ontology/issues/32370”^^anyURI
undecaprenol kinase activity has cross-reference “EC:2.7.1.66”
undecaprenol kinase activity has cross-reference “KEGG_REACTION:R05626”
undecaprenol kinase activity has cross-reference “MetaCyc:UNDECAPRENOL-KINASE-RXN”
undecaprenol kinase activity has cross-reference “RHEA:23752”
undecaprenol kinase activity has cross-reference “RHEA:28122”
undecaprenol kinase activity has narrow synonym “ditrans,polycis-undecaprenol kinase activity”
undecaprenol kinase activity has_related_synonym “all-trans undecaprenol kinase activity”
undecaprenol kinase activity has_related_synonym “di-trans, poly-cis-undecaprenol kinase activity”
undecaprenol kinase activity exactMatch 2.7.1.66
undecaprenol kinase activity narrowMatch UNDECAPRENOL-KINASE-RXN
undecaprenol kinase activity narrowMatch 23752
undecaprenol kinase activity narrowMatch 28122
undecaprenol kinase activity narrowMatch R05626
undecaprenol kinase activity definition “Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate.”
- has cross-reference “PMID:33310291”
- has cross-reference “GOC:curators”
undecaprenol kinase activity comment “Undecaprenol kinase has broad substrate specificity and is capable of phosphorylating all-trans-undecaprenol as well as di-trans,poly-cis-undecaprenol (PMID:33310291).”

undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity `http://purl.obolibrary.org/obo/GO_0050511`

Removed

undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity has_related_synonym “UDP-N-acetyl-D-glucosamine:N-acetyl-alpha-D-muramyl(oyl-L-Ala- gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol beta-1,4-N-acetylglucosaminlytransferase activity”
- has cross-reference “EC:2.4.1.227”

Added

undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity has_related_synonym “UDP-N-acetyl-D-glucosamine:N-acetyl-alpha-D-muramyl(oyl-L-Ala- gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol beta-1,4-N-acetylglucosaminyltransferase activity”
- has cross-reference “EC:2.4.1.227”

unfolded protein holdase activity `http://purl.obolibrary.org/obo/GO_0140309`

Removed

unfolded protein holdase activity definition “A protein carrier activity that binds to a protein in an unfolded state and escorts it to an acceptor molecule or to a specific location. The unfolded protein carrier prevents aggregation of the target protein while its being delivers to its final destination.”
- has cross-reference “PMID:39488384”

Added

unfolded protein holdase activity has narrow synonym “carbohydrate-binding holdase”
unfolded protein holdase activity has narrow synonym “lectin chaperone”
unfolded protein holdase activity definition “A protein carrier activity that binds to a protein in an unfolded state and escorts it to an acceptor molecule or to a specific location. The unfolded protein carrier prevents aggregation of the target protein until it is delivered to its final destination.”
- has cross-reference “PMID:39488384”

urate catabolic process `http://purl.obolibrary.org/obo/GO_0019628`

Removed

urate catabolic process SubClassOf small molecule catabolic process

venom-mediated vasoconstriction `http://purl.obolibrary.org/obo/GO_0044499`

Removed

venom-mediated vasoconstriction definition “A process in which an organism initiates, promotes, or enhances the narrowing (constriction) of blood vessels by small muscles in their walls in another organism via the action of a venom, concomittantly increasing blood pressure in the bitten/stung organism.”
- has cross-reference “PMID:19837656”
- has cross-reference “GOC:fj”

Added

venom-mediated vasoconstriction definition “A process in which an organism initiates, promotes, or enhances the narrowing (constriction) of blood vessels by small muscles in their walls in another organism via the action of a venom, concomitantly increasing blood pressure in the bitten/stung organism.”
- has cross-reference “PMID:19837656”
- has cross-reference “GOC:fj”

venom-mediated vasoconstriction via activation of endothelin receptor signaling pathway `http://purl.obolibrary.org/obo/GO_0140183`

Removed

venom-mediated vasoconstriction via activation of endothelin receptor signaling pathway definition “A process in which an organism promotes the narrowing (constriction) of blood vessels, by inhibiting the widening (dilation) of blood vessels in another organism via the action of a venom that activates endothelin receptor signaling pathway, concomittantly increasing blood pressure in the bitten/stung organism.”
- has cross-reference “PMID:16277978”

Added

venom-mediated vasoconstriction via activation of endothelin receptor signaling pathway definition “A process in which an organism promotes the narrowing (constriction) of blood vessels, by inhibiting the widening (dilation) of blood vessels in another organism via the action of a venom that activates endothelin receptor signaling pathway, concomitantly increasing blood pressure in the bitten/stung organism.”
- has cross-reference “PMID:16277978”

venom-mediated vasodilation `http://purl.obolibrary.org/obo/GO_0044551`

Removed

venom-mediated vasodilation definition “A process in which an organism initiates, promotes, or enhances the widening of blood vessels by small muscles in their walls in another organism via the action of a venom, concomittantly reducing blood pressure in the bitten/stung organism.”
- has cross-reference “PMID:21050868”
- has cross-reference “GOC:ecd”
- has cross-reference “GOC:jl”

Added

venom-mediated vasodilation definition “A process in which an organism initiates, promotes, or enhances the widening of blood vessels by small muscles in their walls in another organism via the action of a venom, concomitantly reducing blood pressure in the bitten/stung organism.”
- has cross-reference “PMID:21050868”
- has cross-reference “GOC:ecd”
- has cross-reference “GOC:jl”

venom-mediated vasodilation by activation of bradykinin receptor signaling pathway `http://purl.obolibrary.org/obo/GO_0140162`

Removed

venom-mediated vasodilation by activation of bradykinin receptor signaling pathway definition “A process in which an organism initiates, promotes, or enhances vasodilation via the action of a venom that activates bradykinin-dependent signaling, concomittantly reducing blood pressure in the bitten/stung organism. This can take place via several mechanisms that affect endogenous bradykinin: either increasing its release by kallikrein-like proteases, increasing bradykinin action by potentiation, or inhibiting bradykinin degradation.”
- has cross-reference “PMID:31370142”

Added

venom-mediated vasodilation by activation of bradykinin receptor signaling pathway definition “A process in which an organism initiates, promotes, or enhances vasodilation via the action of a venom that activates bradykinin-dependent signaling, concomitantly reducing blood pressure in the bitten/stung organism. This can take place via several mechanisms that affect endogenous bradykinin: either increasing its release by kallikrein-like proteases, increasing bradykinin action by potentiation, or inhibiting bradykinin degradation.”
- has cross-reference “PMID:31370142”

venom-mediated vasodilation by activation of nitric oxide-cGMP-mediated signaling `http://purl.obolibrary.org/obo/GO_0140165`

Removed

venom-mediated vasodilation by activation of nitric oxide-cGMP-mediated signaling definition “A process in which an organism initiates, promotes, or enhances vasodilation via the action of a venom that activates nitric oxide-cGMP-mediated signaling, concomittantly reducing blood pressure in the bitten/stung organism.”
- has cross-reference “PMID:10512636”

Added

venom-mediated vasodilation by activation of nitric oxide-cGMP-mediated signaling definition “A process in which an organism initiates, promotes, or enhances vasodilation via the action of a venom that activates nitric oxide-cGMP-mediated signaling, concomitantly reducing blood pressure in the bitten/stung organism.”
- has cross-reference “PMID:10512636”

venom-mediated vasodilation via suppression of angiotensin maturation `http://purl.obolibrary.org/obo/GO_0140166`

Removed

venom-mediated vasodilation via suppression of angiotensin maturation definition “A process in which an organism initiates, promotes, or enhances vasodilation via the action of a venom that prevents angiotensin maturation, concomittantly reducing blood pressure in the bitten/stung organism.”
- has cross-reference “PMID:31370142”

Added

venom-mediated vasodilation via suppression of angiotensin maturation definition “A process in which an organism initiates, promotes, or enhances vasodilation via the action of a venom that prevents angiotensin maturation, concomitantly reducing blood pressure in the bitten/stung organism.”
- has cross-reference “PMID:31370142”

very long-chain fatty-acyl-CoA catabolic process `http://purl.obolibrary.org/obo/GO_0036113`

Removed

very long-chain fatty-acyl-CoA catabolic process comment “While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).”

virion component `http://purl.obolibrary.org/obo/GO_0044423`

Added

virion component definition “Any constituent part of a virion, a complete fully infectious extracellular virus particle.”

vitelline membrane formation `http://purl.obolibrary.org/obo/GO_0030704`

Removed

vitelline membrane formation conformsTo anatomical_structure_formation.yaml

voltage-driven motor activity `http://purl.obolibrary.org/obo/GO_0170085`

Added

Class: voltage-driven motor activity
voltage-driven motor activity term tracker item “https://github.com/geneontology/go-ontology/issues/32556”^^anyURI
voltage-driven motor activity created by “ew”
voltage-driven motor activity creation date “2026-09-02T21:59:45Z”
voltage-driven motor activity has exact synonym “electromechanical transducer activity”
voltage-driven motor activity has exact synonym “voltage-sensitive motor activity”
voltage-driven motor activity has_obo_namespace “molecular_function”
voltage-driven motor activity has_related_synonym “electromotility activity”
voltage-driven motor activity id “GO:0170085”
voltage-driven motor activity definition “A motor activity that detects and converts a change in transmembrane electrical potential directly into mechanical force or a conformational change, without coupling to ATP hydrolysis, ion transport, or a proton-motive force. As an example, mammalian prestin converts voltage changes into outer hair cell movement which is required for sound amplification in the hearing organ.”
- has cross-reference “PMID:12239568”
voltage-driven motor activity label “voltage-driven motor activity”
voltage-driven motor activity SubClassOf energy transducer activity

voltage-gated potassium channel inhibitor activity `http://purl.obolibrary.org/obo/GO_7770090`

Added

Class: voltage-gated potassium channel inhibitor activity
voltage-gated potassium channel inhibitor activity term tracker item “https://github.com/geneontology/go-ontology/issues/32371”^^anyURI
voltage-gated potassium channel inhibitor activity created by “ai4c-agent”
voltage-gated potassium channel inhibitor activity creation date “2026-07-28T16:49:43Z”
voltage-gated potassium channel inhibitor activity has exact synonym “Kv channel inhibitor activity”
voltage-gated potassium channel inhibitor activity has exact synonym “Kv inhibitor activity”
voltage-gated potassium channel inhibitor activity has exact synonym “voltage-gated potassium channel (Kv) inhibitor activity”
voltage-gated potassium channel inhibitor activity has_obo_namespace “molecular_function”
voltage-gated potassium channel inhibitor activity id “GO:7770090”
voltage-gated potassium channel inhibitor activity definition “Binds to and stops, prevents, or reduces the activity of a voltage-gated potassium channel.”
- has cross-reference “PMID:35797055”
voltage-gated potassium channel inhibitor activity label “voltage-gated potassium channel inhibitor activity”
voltage-gated potassium channel inhibitor activity EquivalentTo molecular function inhibitor activity and (directly negatively regulates some voltage-gated potassium channel activity)
voltage-gated potassium channel inhibitor activity SubClassOf potassium channel inhibitor activity
voltage-gated potassium channel inhibitor activity SubClassOf directly negatively regulates some voltage-gated potassium channel activity

zinc chaperone activity `http://purl.obolibrary.org/obo/GO_0140827`

Added

zinc chaperone activity conformsTo molecular_carrier_activity.yaml

zygotic determination of anterior/posterior axis, embryo `http://purl.obolibrary.org/obo/GO_0007354`

Removed

zygotic determination of anterior/posterior axis, embryo definition “The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade.”
- has cross-reference “ISBN:0879694238”
- has cross-reference “http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm”

Added

zygotic determination of anterior/posterior axis, embryo term tracker item “https://github.com/geneontology/go-ontology/issues/18983”^^anyURI
zygotic determination of anterior/posterior axis, embryo definition “The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade.”
- has cross-reference “ISBN:0879694238”

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go-ontology

Ontology comparison

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Ontology imports

Ontology annotations

Removed

Added

‘de novo’ NAD+ biosynthetic process from L-tryptophan http://purl.obolibrary.org/obo/GO_0034354

Added

(+)-larreatricin biosynthetic process http://purl.obolibrary.org/obo/GO_1901709

Removed

Added

(25S)-Delta(7)-dafachronate biosynthetic process http://purl.obolibrary.org/obo/GO_1902056

Removed

Added

(2R)-2-hydroxycarboxylate dehydrogenase (FAD) activity http://purl.obolibrary.org/obo/GO_0140174

Removed

Added

(R)-mandelate dehydrogenase (NAD+) activity http://purl.obolibrary.org/obo/GO_0097620

Removed

Added

1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity http://purl.obolibrary.org/obo/GO_0062181

Removed

Added

2-(3-amino-3-carboxypropyl)histidine synthase complex http://purl.obolibrary.org/obo/GO_0120513

Removed

Added

2-oxoadipate decarboxylation to glutaryl-CoA http://purl.obolibrary.org/obo/GO_0120578

Added

2-oxoadipate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0160166

Added

4’-phosphopantetheine phosphatase activity http://purl.obolibrary.org/obo/GO_7770095

Added

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex http://purl.obolibrary.org/obo/GO_0043540

Removed

Added

6-phosphofructokinase activity http://purl.obolibrary.org/obo/GO_0003872

Removed

Added

7-methylguanosine cap hypermethylation http://purl.obolibrary.org/obo/GO_0036261

Removed

Added

ABC-type cadmium transporter activity http://purl.obolibrary.org/obo/GO_0015434

Added

ABC-type protein transporter activity http://purl.obolibrary.org/obo/GO_0015462

Removed

Added

ATG2-ATG18 complex http://purl.obolibrary.org/obo/GO_0062079

Removed

Added

ATP-dependent folded protein transmembrane transporter activity http://purl.obolibrary.org/obo/GO_7770098

Added

ATP-dependent protein-RNA complex displacement activity http://purl.obolibrary.org/obo/GO_7770106

Added

ATPase-coupled L-glutamate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0102013

Removed

Added

Atg9-containing vesicle http://purl.obolibrary.org/obo/GO_7770115

Added

B cell cytokine production http://purl.obolibrary.org/obo/GO_0002368

Removed

Added

B cell mediated immunity http://purl.obolibrary.org/obo/GO_0019724

Removed

B cell tolerance induction in mucosal-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0002402

Removed

Added

B-type glycerophospholipase activity http://purl.obolibrary.org/obo/GO_0102545

Removed

Added

CD4-positive, alpha-beta T cell cytokine production http://purl.obolibrary.org/obo/GO_0035743

Removed

Added

D-glucosamine biosynthetic process http://purl.obolibrary.org/obo/GO_0006042

Removed

D-glucosamine catabolic process http://purl.obolibrary.org/obo/GO_0006043

Removed

D-lactate dehydrogenase (FAD) activity http://purl.obolibrary.org/obo/GO_0140170

Added

‘de novo’ NAD+ biosynthetic process from L-tryptophan `http://purl.obolibrary.org/obo/GO_0034354`

(+)-larreatricin biosynthetic process `http://purl.obolibrary.org/obo/GO_1901709`

(25S)-Delta(7)-dafachronate biosynthetic process `http://purl.obolibrary.org/obo/GO_1902056`

(2R)-2-hydroxycarboxylate dehydrogenase (FAD) activity `http://purl.obolibrary.org/obo/GO_0140174`

(R)-mandelate dehydrogenase (NAD+) activity `http://purl.obolibrary.org/obo/GO_0097620`

1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity `http://purl.obolibrary.org/obo/GO_0062181`

2-(3-amino-3-carboxypropyl)histidine synthase complex `http://purl.obolibrary.org/obo/GO_0120513`

2-oxoadipate decarboxylation to glutaryl-CoA `http://purl.obolibrary.org/obo/GO_0120578`

2-oxoadipate dehydrogenase activity `http://purl.obolibrary.org/obo/GO_0160166`

4’-phosphopantetheine phosphatase activity `http://purl.obolibrary.org/obo/GO_7770095`

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex `http://purl.obolibrary.org/obo/GO_0043540`

6-phosphofructokinase activity `http://purl.obolibrary.org/obo/GO_0003872`

7-methylguanosine cap hypermethylation `http://purl.obolibrary.org/obo/GO_0036261`

ABC-type cadmium transporter activity `http://purl.obolibrary.org/obo/GO_0015434`

ABC-type protein transporter activity `http://purl.obolibrary.org/obo/GO_0015462`

ATG2-ATG18 complex `http://purl.obolibrary.org/obo/GO_0062079`

ATP-dependent folded protein transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_7770098`

ATP-dependent protein-RNA complex displacement activity `http://purl.obolibrary.org/obo/GO_7770106`

ATPase-coupled L-glutamate transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0102013`

Atg9-containing vesicle `http://purl.obolibrary.org/obo/GO_7770115`

B cell cytokine production `http://purl.obolibrary.org/obo/GO_0002368`

B cell mediated immunity `http://purl.obolibrary.org/obo/GO_0019724`

B cell tolerance induction in mucosal-associated lymphoid tissue `http://purl.obolibrary.org/obo/GO_0002402`

B-type glycerophospholipase activity `http://purl.obolibrary.org/obo/GO_0102545`

CD4-positive, alpha-beta T cell cytokine production `http://purl.obolibrary.org/obo/GO_0035743`

D-glucosamine biosynthetic process `http://purl.obolibrary.org/obo/GO_0006042`

D-glucosamine catabolic process `http://purl.obolibrary.org/obo/GO_0006043`

D-lactate dehydrogenase (FAD) activity `http://purl.obolibrary.org/obo/GO_0140170`

D-sorbitol biosynthetic process `http://purl.obolibrary.org/obo/GO_0006061`

D-xylose reductase (NADPH) activity `http://purl.obolibrary.org/obo/GO_0032866`

DNA recombinase auxiliary factor complex `http://purl.obolibrary.org/obo/GO_0120231`

ER lumen protein retrieval receptor activity `http://purl.obolibrary.org/obo/GO_0046923`

ER membrane protein retrieval receptor activity `http://purl.obolibrary.org/obo/GO_7770094`

ER overload response `http://purl.obolibrary.org/obo/GO_0006983`

ERAD quality control pathway `http://purl.obolibrary.org/obo/GO_0036503`

ESCRT III complex `http://purl.obolibrary.org/obo/GO_0000815`

FAD regeneration via ETF:ETFQO system `http://purl.obolibrary.org/obo/GO_7770096`

FMN adenylyltransferase activity `http://purl.obolibrary.org/obo/GO_0003919`

G-protein beta/gamma-subunit complex `http://purl.obolibrary.org/obo/GO_0031680`

GPI anchor remodeling `http://purl.obolibrary.org/obo/GO_0120574`

Hrd1p ubiquitin ligase complex `http://purl.obolibrary.org/obo/GO_0000836`

L-arabinose reductase (NADPH) activity `http://purl.obolibrary.org/obo/GO_0032867`

L-malate dehydrogenase (NAD+) activity `http://purl.obolibrary.org/obo/GO_0030060`

L-methionine cycle `http://purl.obolibrary.org/obo/GO_0033353`

L-phenylalanine oxidase activity `http://purl.obolibrary.org/obo/GO_0106329`

N-acetylglucosamine biosynthetic process `http://purl.obolibrary.org/obo/GO_0006045`

N-acetylglucosamine catabolic process `http://purl.obolibrary.org/obo/GO_0006046`

N-acetylmannosamine biosynthetic process `http://purl.obolibrary.org/obo/GO_0006052`

N-acetylmannosamine catabolic process `http://purl.obolibrary.org/obo/GO_0006053`

N-acetylneuraminate biosynthetic process `http://purl.obolibrary.org/obo/GO_0046380`

N-acetylneuraminate catabolic process `http://purl.obolibrary.org/obo/GO_0019262`

NAD+ nucleosidase activity, cyclic ADP-ribose generating `http://purl.obolibrary.org/obo/GO_0061809`

NAD+-protein-arginine ADP-ribosyltransferase activity `http://purl.obolibrary.org/obo/GO_0106274`

NAD-cap decapping `http://purl.obolibrary.org/obo/GO_0110155`

NADH-dependent peroxiredoxin activity `http://purl.obolibrary.org/obo/GO_0102039`

NADP+ biosynthetic process `http://purl.obolibrary.org/obo/GO_0006741`