go-ontology

Ontology comparison

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Ontology IRI: http://purl.obolibrary.org/obo/go.owl
Version IRI: http://purl.obolibrary.org/obo/go/releases/2026-03-25/go.owl
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Ontology IRI: http://purl.obolibrary.org/obo/go.owl
Version IRI: http://purl.obolibrary.org/obo/go/releases/2026-04-20/go.owl
Loaded from: file:/__w/go-ontology/go-ontology/src/ontology/go.ofn

versionInfo “2026-03-25”

versionInfo “2026-04-20”

(R)-2-hydroxy-4-methylpentanoate CoA-transferase activity has_exact_synonym “(R)-2-hydroxyisocaproate CoA-transferase activity”
(R)-2-hydroxy-4-methylpentanoate CoA-transferase activity definition “Catalysis of the reaction: (R)-2-hydroxyisocaproate + isocaproyl-CoA = (R)-2-hydroxyisocaproyl-CoA + isocaproate.”
- database_cross_reference “PMID:16957230”
(R)-2-hydroxy-4-methylpentanoate CoA-transferase activity label “2-hydroxyisocaproate CoA-transferase activity”

1,8-cineole synthase activity definition “Catalysis of the reaction: geranyl diphosphate(3-) + H2O = 1,8-cineole + diphosphoric acid.”
- database_cross_reference “GOC:pz”
- database_cross_reference “RHEA:32543”

1,8-cineole synthase activity definition “Catalysis of the reaction: geranyl diphosphate(3-) + H2O = 1,8-cineole + diphosphoric acid.”
- database_cross_reference “RHEA:32543”

2,5-dioxovalerate dehydrogenase (NADP+) activity definition “Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+.”
- database_cross_reference “EC:1.2.1.26”
- database_cross_reference “MetaCyc:25-DIOXOVALERATE-DEHYDROGENASE-RXN”

2,5-dioxovalerate dehydrogenase (NADP+) activity definition “Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+.”
- database_cross_reference “RHEA:11296”

2-aminobenzenesulfonate 2,3-dioxygenase activity definition “Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H+ + NADH + O2 = 2,3-dihydroxybenzenesulfonate + NAD+ + NH4. 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol.”
- database_cross_reference “EC:1.14.12.14”
- database_cross_reference “RHEA:23468”

2-aminobenzenesulfonate 2,3-dioxygenase activity definition “Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H+ + NADH + O2 = 2,3-dihydroxybenzenesulfonate + NAD+ + NH4. 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol.”
- database_cross_reference “RHEA:23468”

2-hydroxyquinoline 5,6-dioxygenase activity definition “Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+.”
- database_cross_reference “EC:1.14.12.16”

2-hydroxyquinoline 5,6-dioxygenase activity definition “Catalysis of the reaction: quinolin-2-ol + NADH + O2 + H+ = 5,6-dihydroquinoline-2,5,6-triol + NAD+.”
- database_cross_reference “RHEA:10976”

3-butenylglucosinolate 2-hydroxylase activity definition “Catalysis of the reaction: gluconapin + a reduced electron acceptor + O2 = xi-progoitrin + an oxidized electron acceptor + H2O.”
- database_cross_reference “PMID:18945935”

3-butenylglucosinolate 2-hydroxylase activity definition “Catalysis of the reaction: gluconapin + a reduced electron acceptor + O2 = progoitrin + an oxidized electron acceptor + H2O.”
- database_cross_reference “RHEA:60628”
- database_cross_reference “PMID:18945935”

3-chlorobenzoate-3,4-oxygenase activity definition “Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor = 3-chlorobenzoate-cis-3,4-diol + an oxidized electron acceptor.”
- database_cross_reference “GOC:pz”
- database_cross_reference “PMID:8285670”

3-chlorobenzoate-3,4-oxygenase activity definition “Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor = 3-chlorobenzoate-cis-3,4-diol + an oxidized electron acceptor.”
- database_cross_reference “PMID:8285670”
- database_cross_reference “PMID:38488372”

3-oxoadipate CoA-transferase activity definition “Catalysis of the reaction: succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA.”
- database_cross_reference “EC:2.8.3.6”
- database_cross_reference “MetaCyc:3-OXOADIPATE-COA-TRANSFERASE-RXN”

3-oxoadipate CoA-transferase activity definition “Catalysis of the reaction: 3-oxoadipate + succinyl-CoA = 3-oxoadipyl-CoA + succinate.”
- database_cross_reference “RHEA:12048”

3-phenylpropionate dioxygenase activity definition “Catalysis of the reaction: 3-phenylpropionate + NADH + H+ + O2 = NAD+ + cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol.”
- database_cross_reference “UM-BBD_enzymeID:e0307”

3-phenylpropionate dioxygenase activity definition “Catalysis of the reaction: 3-phenylpropanoate + NADH + O2 + H+ = 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+.”
- database_cross_reference “RHEA:20357”

4-O-methyl-glucuronoyl methylesterase activity definition “Catalysis of the reaction: [X]-4-O-methyl-D-glucuronic acid + H2O = [X]-OH + methyl-D-glucuronic acid. This reaction is the hydrolysis of the ester linkage between 4-O-methyl-D-glucuronic acid (MeGlcA) and an alcohol (-OH) group attached to a molecule, denoted here as [X].”
- database_cross_reference “GOC:mengo_curators”
- database_cross_reference “PMID:16876163”

4-aminobenzoate biosynthetic process definition “The chemical reactions and pathways resulting in the formation of 4-aminobenzoate, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.”
- database_cross_reference “PMID:11377864”
- database_cross_reference “MetaCyc:PWY-6543”
- database_cross_reference “PMID:11960743”
- database_cross_reference “ISBN:0198506732”
4-aminobenzoate biosynthetic process SubClassOf obsolete para-aminobenzoic acid metabolic process

4-aminobenzoate biosynthetic process definition “The chemical reactions and pathways resulting in the formation of 4-aminobenzoate, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.”
- database_cross_reference “PMID:11377864”
- database_cross_reference “MetaCyc:PWY-6543”
- database_cross_reference “PMID:11960743”
4-aminobenzoate biosynthetic process SubClassOf benzene-containing compound metabolic process

4-chlorophenylacetate 3,4-dioxygenase activity definition “Catalysis of the reaction: 4-chlorophenylacetate + NADH + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD+.”
- database_cross_reference “EC:1.14.12.9”
- database_cross_reference “RHEA:14689”

4-chlorophenylacetate 3,4-dioxygenase activity definition “Catalysis of the reaction: 4-chlorophenylacetate + NADH + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD+.”
- database_cross_reference “RHEA:14689”

4-hydroxy-L-isoleucine dehydrogenase activity definition “Catalysis of the reaction: (2S,3R,4S)-4-hydroxy-L-isoleucine + NAD = (2S,3R)-2-amino-3-methyl-4-ketopentanoate + NADH + H+.”
- database_cross_reference “GOC:pz”
- database_cross_reference “PMID:21069315”

4-hydroxybutanoyl-CoA dehydratase activity definition “Catalysis of the reaction: 4-hydroxybutanoyl-CoA = vinylacetyl-CoA + H2O.”
- database_cross_reference “EC:4.2.1.120”

4-hydroxybutanoyl-CoA dehydratase activity definition “Catalysis of the reaction: 4-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2O.”
- database_cross_reference “RHEA:26530”

4-sulfobenzoate 3,4-dioxygenase activity definition “Catalysis of the reaction: 4-sulfobenzoate + H+ + NADH + O2 = 3,4-dihydroxybenzoate + NAD+ + sulfite.”
- database_cross_reference “EC:1.14.12.8”
- database_cross_reference “RHEA:13937”

4-sulfobenzoate 3,4-dioxygenase activity definition “Catalysis of the reaction: 4-sulfobenzoate + H+ + NADH + O2 = 3,4-dihydroxybenzoate + NAD+ + sulfite.”
- database_cross_reference “RHEA:13937”

5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity term tracker item “https://github.com/geneontology/go-ontology/issues/31862”^^anyURI
5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity database_cross_reference “RHEA:48656”
5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity exactMatch 48656
5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity definition “Catalysis of the reaction: 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate (5-HETE) + reduced [NADPH-hemoprotein reductase] + O2 = 5,20-dihydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate (5-oxo-ETE) + oxidized [NADPH-hemoprotein reductase] + H2O + H+.”
- database_cross_reference “PMID:9675028”
- database_cross_reference “RHEA:48656”
- database_cross_reference “PMID:1326548”

5-hydroxypentanoate CoA-transferase activity definition “Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate.”
- database_cross_reference “RHEA:23496”
- database_cross_reference “EC:2.8.3.14”

5-hydroxypentanoate CoA-transferase activity definition “Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate.”
- database_cross_reference “RHEA:23496”

7,8-dihydro-D-neopterin 2’,3’-cyclic phosphate phosphodiesterase activity definition “Catalysis of the reaction: 7,8-dihydro-D-neopterin 2’,3’-cyclic phosphate + H2O = 7,8-dihydroneopterin 3’-phosphate + H+.”
- database_cross_reference “PMID:19746965”
- database_cross_reference “GOC:mengo_curators”

ADP-ribosylglutamate-[protein] hydrolase activity definition “Catalysis of the reaction: (ADP-D-ribosyl)-L-glutamyl-[protein] + H2O = L-glutamyl-[protein] + ADP-ribose.”
- database_cross_reference “PMID:23481255”
ADP-ribosylglutamate-[protein] hydrolase activity label “ADP-ribosylglutamate hydrolase activity”

ADP-ribosylserine-[protein] hydrolase activity definition “Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose.”
- database_cross_reference “RHEA:58256”
- database_cross_reference “PMID:28650317”
- database_cross_reference “PMID:29234005”
ADP-ribosylserine-[protein] hydrolase activity label “ADP-ribosylserine hydrolase activity”

ADP-ribosylserine-[protein] hydrolase activity term tracker item “https://github.com/geneontology/go-ontology/issues/31850”^^anyURI
ADP-ribosylserine-[protein] hydrolase activity has_exact_synonym “ADP-ribosylserine hydrolase activity”
ADP-ribosylserine-[protein] hydrolase activity definition “Catalysis of the reaction: O-(ADP-D-ribosyl)-L-seryl-[protein] + H2O = ADP-D-ribose + L-seryl-[protein].”
- database_cross_reference “RHEA:58256”
- database_cross_reference “PMID:28650317”
- database_cross_reference “PMID:29234005”
ADP-ribosylserine-[protein] hydrolase activity label “ADP-ribosylserine-[protein] hydrolase activity”

Cypridina-luciferin 2-monooxygenase activity definition “Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light.”
- database_cross_reference “MetaCyc:CYPRIDINA-LUCIFERIN-2-MONOOXYGENASE-RXN”
- database_cross_reference “EC:1.13.12.6”

Cypridina-luciferin 2-monooxygenase activity definition “Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light.”
- database_cross_reference “EC:1.13.12.6”

D-glucosamine biosynthetic process label “glucosamine biosynthetic process”

D-glucosamine catabolic process label “glucosamine catabolic process”

D-glucosamine metabolic process label “glucosamine metabolic process”

L-arginine transmembrane transport term tracker item “https://github.com/geneontology/go-ontology/issues/31823”^^anyURI

L-citrulline biosynthetic process definition “The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.”
- database_cross_reference “ISBN:0198506732”
L-citrulline biosynthetic process label “citrulline biosynthetic process”
L-citrulline biosynthetic process SubClassOf obsolete citrulline metabolic process

L-citrulline biosynthetic process has_broad_synonym “citrulline biosynthetic process”
L-citrulline biosynthetic process definition “The chemical reactions and pathways resulting in the formation of L-citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.”
- database_cross_reference “ISBN:0198506732”
L-citrulline biosynthetic process label “L-citrulline biosynthetic process”

L-cysteine export across plasma membrane definition “The directed movement of cysteine from inside of a cell, across the plasma membrane and into the extracellular region.”
- database_cross_reference “GOC:mlg”
L-cysteine export across plasma membrane label “cysteine export across plasma membrane”

L-cysteine export across plasma membrane term tracker item “https://github.com/geneontology/go-ontology/issues/27479”^^anyURI
L-cysteine export across plasma membrane has_broad_synonym “L-cysteine export”
L-cysteine export across plasma membrane has_broad_synonym “cysteine export across plasma membrane”
L-cysteine export across plasma membrane definition “The directed movement of L-cysteine from inside of a cell, across the plasma membrane and into the extracellular region.”
- database_cross_reference “GOC:mlg”
L-cysteine export across plasma membrane label “L-cysteine export across plasma membrane”

L-cysteine transmembrane transporter activity definition “Enables the transfer of cysteine from one side of a membrane to the other.”
- database_cross_reference “GOC:mah”
L-cysteine transmembrane transporter activity label “cysteine transmembrane transporter activity”

L-cysteine transport has_narrow_synonym “L-cysteine transport”
L-cysteine transport definition “The directed movement of cysteine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.”
- database_cross_reference “GOC:jl”
- database_cross_reference “ISBN:0198506732”
L-cysteine transport label “cysteine transport”
L-cysteine transport SubClassOf obsolete organic cation transport

L-cysteine transport has_broad_synonym “cysteine transport”
L-cysteine transport definition “The directed movement of L-cysteine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.”
- database_cross_reference “GOC:jl”
- database_cross_reference “ISBN:0198506732”
L-cysteine transport label “L-cysteine transport”
L-cysteine transport SubClassOf L-amino acid transport

L-isoleucine catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31839”^^anyURI
L-isoleucine catabolic process has_narrow_synonym “L-isoleucine catabolic process via Ehrlich pathway”
L-isoleucine catabolic process has_narrow_synonym “L-isoleucine degradation via Ehrlich pathway”

L-leucine catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31839”^^anyURI
L-leucine catabolic process has_narrow_synonym “L-leucine degradation via Ehrlich pathway”
L-leucine catabolic process has_narrow_synonym “L-methionine catabolic process via Ehrlich pathway”

L-lysine 2-monooxygenase activity label “lysine 2-monooxygenase activity”

L-methionine catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31839”^^anyURI
L-methionine catabolic process has_narrow_synonym “L-methionine catabolic process via Ehrlich pathway”
L-methionine catabolic process has_narrow_synonym “L-methionine degradation via Ehrlich pathway”

L-ornithine biosynthetic process label “ornithine biosynthetic process”

L-phenylalanine catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31839”^^anyURI
L-phenylalanine catabolic process has_narrow_synonym “L-phenylalanine catabolic process via Ehrlich pathway”
L-phenylalanine catabolic process has_narrow_synonym “L-phenylalanine degradation via Ehrlich pathway”

L-tryptophan catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31839”^^anyURI
L-tryptophan catabolic process has_narrow_synonym “L-tryptophan catabolic process via Ehrlich pathway”
L-tryptophan catabolic process has_narrow_synonym “L-tryptophan degradation via Ehrlich pathway”

L-valine catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31839”^^anyURI
L-valine catabolic process has_narrow_synonym “valine degradation via Ehrlich pathway”

Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity definition “Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin.”
- database_cross_reference “MetaCyc:1.13.12.7-RXN”
- database_cross_reference “EC:1.13.12.7”

Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity definition “Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin.”
- database_cross_reference “EC:1.13.12.7”

RNA translocase activity comment “Note that some gene products that possess DNA translocase activity, such as members of the FtsK/SpoIIIE family, can be fixed in place by interactions with other components of the cell; the relative movement between the protein and DNA bound to it results in movement of the DNA within the cell, often across a membrane.”

RNA translocase activity term tracker item “https://github.com/geneontology/go-ontology/issues/31772”^^anyURI

Renilla-luciferin 2-monooxygenase activity definition “Catalysis of the reaction: Renilla luciferin + O2 = oxidized Renilla luciferin + CO2 + light.”
- database_cross_reference “MetaCyc:RENILLA-LUCIFERIN-2-MONOOXYGENASE-RXN”
- database_cross_reference “EC:1.13.12.5”

Renilla-luciferin 2-monooxygenase activity definition “Catalysis of the reaction: Renilla luciferin + O2 = oxidized Renilla luciferin + CO2 + light.”
- database_cross_reference “EC:1.13.12.5”

Watasenia-luciferin 2-monooxygenase activity definition “Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light.”
- database_cross_reference “MetaCyc:WATASEMIA-LUCIFERIN-2-MONOOXYGENASE-RXN”
- database_cross_reference “EC:1.13.12.8”

Watasenia-luciferin 2-monooxygenase activity definition “Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light.”
- database_cross_reference “EC:1.13.12.8”

acetate CoA-transferase activity definition “Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.”
- database_cross_reference “EC:2.8.3.8”

acetate CoA-transferase activity definition “Catalysis of the reaction: an acyl-CoA + acetate = a carboxylate + acetyl-CoA.”
- database_cross_reference “RHEA:13381”

acrolein reductase activity definition “Catalysis of the reaction: acrolein + NADPH + H+ = propanal + NADP.”
- database_cross_reference “GOC:pz”
- database_cross_reference “PMID:21169366”

autophagosome-membrane adaptor activity definition “The binding activity of a molecule that brings together a target membrane and an autophagosome during autophagy.”
- database_cross_reference “PMID:36635405”
- database_cross_reference “PMID:30544615”
autophagosome-membrane adaptor activity SubClassOf protein-membrane adaptor activity

autophagosome-membrane adaptor activity term tracker item “https://github.com/geneontology/go-ontology/issues/31866”^^anyURI
autophagosome-membrane adaptor activity definition “The binding activity of a molecule that brings together a target membrane and an autophagosome membrane during autophagy.”
- database_cross_reference “PMID:36635405”
- database_cross_reference “PMID:30544615”
autophagosome-membrane adaptor activity SubClassOf membrane-membrane adaptor activity

benzene 1,2-dioxygenase activity definition “Catalysis of the reaction: benzene + H+ + NADH + O2 = cis-cyclohexa-3,5-diene-1,2-diol + NAD+.”
- database_cross_reference “EC:1.14.12.3”
- database_cross_reference “RHEA:13813”

benzene 1,2-dioxygenase activity definition “Catalysis of the reaction: benzene + NADH + O2 + H+ = cis-1,2-dihydrobenzene-1,2-diol + NAD+.”
- database_cross_reference “RHEA:13813”

benzoate 1,2-dioxygenase activity definition “Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+.”
- database_cross_reference “EC:1.14.12.10”

benzoate 1,2-dioxygenase activity definition “Catalysis of the reaction: benzoate + NADH + O2 + H+ = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+.”
- database_cross_reference “RHEA:12633”

biphenyl 2,3-dioxygenase activity definition “Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+.”
- database_cross_reference “EC:1.14.12.18”

biphenyl 2,3-dioxygenase activity definition “Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+.”
- database_cross_reference “RHEA:18165”

butyrate-acetoacetate CoA-transferase activity definition “Catalysis of the reaction: acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate.”
- database_cross_reference “RHEA:12961”
- database_cross_reference “EC:2.8.3.9”

butyrate-acetoacetate CoA-transferase activity definition “Catalysis of the reaction: acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate.”
- database_cross_reference “RHEA:12961”

cinnamoyl-CoA:phenyllactate CoA-transferase activity definition “Catalysis of the reaction: (R)-3-phenyllactate + [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonatooxy)oxolan-2-yl]methyl {[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-{[(2E)-3-phenylprop-2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}carbamoyl)propyl phosphonato]oxy}phosphonate = (R)-3-phenyllactoyl-CoA + trans-cinnamate.”
- database_cross_reference “RHEA:15601”
- database_cross_reference “EC:2.8.3.17”

cinnamoyl-CoA:phenyllactate CoA-transferase activity definition “Catalysis of the reaction: (E)-cinnamoyl-CoA + (R)-3-phenyllactate = (R)-3-phenyllactoyl-CoA + (E)-cinnamate.”
- database_cross_reference “RHEA:15601”

citramalate CoA-transferase activity definition “Catalysis of the reaction: acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA.”
- database_cross_reference “MetaCyc:CITRAMALATE-COA-TRANSFERASE-RXN”
- database_cross_reference “EC:2.8.3.11”

citramalate CoA-transferase activity definition “Catalysis of the reaction: citramalate + acetyl-CoA = (3S)-citramalyl-CoA + acetate.”
- database_cross_reference “RHEA:17621”

citrate CoA-transferase activity definition “Catalysis of the reaction: acetyl-CoA + citrate = acetate + (3S)-citryl-CoA.”
- database_cross_reference “EC:2.8.3.10”

citrate CoA-transferase activity definition “Catalysis of the reaction: acetyl-CoA + citrate = acetate + (3S)-citryl-CoA.”
- database_cross_reference “RHEA:19405”

cysteinyl-tRNA aminoacylation definition “The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a cysteine-accetping tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- database_cross_reference “GOC:mcc”
- database_cross_reference “ISBN:0716730510”

cysteinyl-tRNA aminoacylation definition “The process of coupling L-cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2’-OH group of a cysteine-accepting tRNA. The 2’-O-aminoacyl-tRNA will ultimately migrate to the 3’ position via transesterification.”
- database_cross_reference “GOC:mcc”
- database_cross_reference “ISBN:0716730510”

cytoskeletal adaptor activity term tracker item “https://github.com/geneontology/go-ontology/issues/19185”^^anyURI
cytoskeletal adaptor activity has_narrow_synonym “cytoskeletal anchor activity”
cytoskeletal adaptor activity label “cytoskeletal adaptor activity”

dibenzofuran 4,4a-dioxygenase activity definition “Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2’,3-trihydroxybiphenyl + NAD+.”
- database_cross_reference “MetaCyc:R606-RXN”
- database_cross_reference “RHEA:42460”

dibenzofuran 4,4a-dioxygenase activity definition “Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2’,3-trihydroxybiphenyl + NAD+.”
- database_cross_reference “RHEA:42460”

endoplasmic reticulum-autophagosome adaptor activity definition “The binding activity of a molecule that brings together an ER membrane and an autophagosome during reticulophagy.”
- database_cross_reference “PMID:32735772”

endoplasmic reticulum-autophagosome adaptor activity term tracker item “https://github.com/geneontology/go-ontology/issues/31866”^^anyURI
endoplasmic reticulum-autophagosome adaptor activity definition “The binding activity of a molecule that brings together an ER membrane and an autophagosome membrane during reticulophagy.”
- database_cross_reference “PMID:32735772”

endoplasmic reticulum-endosome tether activity definition “The binding activity of a molecule that brings together an endosome and an ER membrane either via membrane lipid binding or by interacting with an endosome protein, to establish and facilitate organelle exchange.”
- database_cross_reference “PMID:33124732”

endoplasmic reticulum-endosome tether activity term tracker item “https://github.com/geneontology/go-ontology/issues/31866”^^anyURI
endoplasmic reticulum-endosome tether activity definition “The binding activity of a molecule that brings together an endosome membrane and an ER membrane either via membrane lipid binding or by interacting with an endosome protein, to establish and facilitate organelle exchange.”
- database_cross_reference “PMID:33124732”

formyl-CoA transferase activity definition “Catalysis of the reaction: formyl-CoA + oxalate = formate + oxalyl-CoA.”
- database_cross_reference “RHEA:16545”
- database_cross_reference “EC:2.8.3.16”

formyl-CoA transferase activity definition “Catalysis of the reaction: formyl-CoA + oxalate = formate + oxalyl-CoA.”
- database_cross_reference “RHEA:16545”

glutaconate CoA-transferase activity definition “Catalysis of the reaction: acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA.”
- database_cross_reference “EC:2.8.3.12”

glutaconate CoA-transferase activity definition “Catalysis of the reaction: trans-glutaconate + acetyl-CoA = (2E)-glutaconyl-CoA + acetate.”
- database_cross_reference “RHEA:23208”

glutamate-cysteine ligase complex definition “An enzyme complex that catalyzes the ligation of glutamate to cysteine, forming glutamylcysteine.”
- database_cross_reference “PMID:9675072”

glutamate-cysteine ligase complex definition “An enzyme complex that catalyzes the ligation of L-glutamate to L-cysteine, forming gamma-L-glutamyl-L-cysteine.”
- database_cross_reference “PMID:9675072”

glutamic-type endopeptidase activity definition “OBSOLETE. Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.”
- database_cross_reference “GOC:mah”
- database_cross_reference “https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE”
- database_cross_reference “https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE”
glutamic-type endopeptidase activity deprecated true
glutamic-type endopeptidase activity comment “This term was obsoleted because it represents a specific substrate.”
glutamic-type endopeptidase activity label “obsolete glutamic-type endopeptidase activity”

glutamic-type endopeptidase activity term tracker item “https://github.com/geneontology/go-ontology/issues/31893”^^anyURI
glutamic-type endopeptidase activity definition “Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.”
- database_cross_reference “GOC:mah”
- database_cross_reference “https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE”
- database_cross_reference “https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE”
glutamic-type endopeptidase activity comment “Unobsoleted, since similar terms exist.”
glutamic-type endopeptidase activity label “glutamic-type endopeptidase activity”
glutamic-type endopeptidase activity SubClassOf endopeptidase activity
glutamic-type endopeptidase activity SubClassOf glutamic-type peptidase activity

intracellular cysteine homeostasis definition “A homeostatic process involved in the maintenance of a steady state level of cysteine within a cell.”
- database_cross_reference “PMID:19955263”

intracellular cysteine homeostasis definition “A homeostatic process involved in the maintenance of a steady state level of L-cysteine within a cell.”
- database_cross_reference “PMID:19955263”

ketone body biosynthetic process definition “The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.”
- database_cross_reference “ISBN:0198506732”
ketone body biosynthetic process SubClassOf obsolete ketone body metabolic process

ketone body biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/31806”^^anyURI
ketone body biosynthetic process database_cross_reference “MetaCyc:PWY66-367”
ketone body biosynthetic process has_exact_synonym “ketogenesis”
ketone body biosynthetic process definition “The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.”
- database_cross_reference “MetaCyc:PWY66-367”

ketone body catabolic process definition “The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.”
- database_cross_reference “ISBN:0198506732”
ketone body catabolic process SubClassOf obsolete ketone body metabolic process

ketone body catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31806”^^anyURI
ketone body catabolic process definition “The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.”
- database_cross_reference “MetaCyc:PWY66-367”

malonate CoA-transferase activity definition “Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA.”
- database_cross_reference “EC:2.8.3.3”
- database_cross_reference “RHEA:18817”

malonate CoA-transferase activity definition “Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA.”
- database_cross_reference “RHEA:18817”

mating projection actin fusion focus definition “A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. Actin filaments form an aster-like structure from this location.”
- database_cross_reference “PMID:25825517”

mating projection actin fusion focus term tracker item “https://github.com/geneontology/go-ontology/issues/31774”^^anyURI
mating projection actin fusion focus definition “A focus at the mating projection tip where the cell wall is degraded during cytogamy. Actin filaments form an aster-like structure from this location.”
- database_cross_reference “PMID:25825517”

mating projection tip cell wall disassembly definition “Any fungal-type cell wall disassembly that is involved in conjugation with cellular fusion.”
- database_cross_reference “GO_REF:0000060”
- database_cross_reference “PMID:25825517”
- database_cross_reference “GOC:TermGenie”
mating projection tip cell wall disassembly label “fungal-type cell wall disassembly involved in conjugation with cellular fusion”

mating projection tip cell wall disassembly term tracker item “https://github.com/geneontology/go-ontology/issues/31753”^^anyURI
mating projection tip cell wall disassembly has_exact_synonym “fungal-type cell wall disassembly involved in conjugation with cellular fusion”
mating projection tip cell wall disassembly definition “Any fungal-type cell wall disassembly that is involved in conjugation with cellular fusion, where the cell wall is locally disassembled to enable conjugation with cellular fusion.”
- database_cross_reference “GO_REF:0000060”
- database_cross_reference “PMID:25825517”
- database_cross_reference “GOC:TermGenie”
mating projection tip cell wall disassembly label “mating projection tip cell wall disassembly”

membrane-membrane adaptor activity definition “The binding activity of a molecule that brings together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle.”
- database_cross_reference “GOC:curators”

membrane-membrane adaptor activity definition “The binding activity of a molecule that brings together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex, vesicle or organelle.”
- database_cross_reference “GOC:curators”

mitochondrial cysteinyl-tRNA aminoacylation definition “The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- database_cross_reference “GOC:mah”
- database_cross_reference “GOC:mcc”

mitochondrial cysteinyl-tRNA aminoacylation definition “The process of coupling L-cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2’- or the 3’-hydroxyl group of the 3’-adenosine residue of the tRNA.”
- database_cross_reference “GOC:mah”
- database_cross_reference “GOC:mcc”

mitochondrial gene expression definition “The process in which a mitochondrial gene’s sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.”
- database_cross_reference “PMID:27058308”

mitochondrial gene expression term tracker item “https://github.com/geneontology/go-ontology/issues/31659”^^anyURI
mitochondrial gene expression definition “The process of transcribing and translating the mitochondrial genome (mtDNA) to produce at least a subset of oxidative phosphorylation (OXPHOS) proteins, 2 rRNAs, and mitochondrial tRNAs, which are critical for ATP production. Protein maturation is included when required to form an active form of a product from an inactive precursor form.”
- database_cross_reference “PMID:27058308”
- database_cross_reference “PMID:38117001”
- database_cross_reference “PMID:31861673”

mitochondrial tRNA wobble position uridine thiolation definition “The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.”
- database_cross_reference “PMID:15509579”

mitochondrial tRNA wobble position uridine thiolation definition “The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from L-cysteine to position C2 by several steps.”
- database_cross_reference “PMID:15509579”

mitochondrion autophagosome adaptor activity definition “The binding activity of a molecule that brings together a mitochondrial membrane and an autophagosome during mitophagy.”
- database_cross_reference “PMID:33138913”

mitochondrion autophagosome adaptor activity term tracker item “https://github.com/geneontology/go-ontology/issues/31866”^^anyURI
mitochondrion autophagosome adaptor activity definition “The binding activity of a molecule that brings together a mitochondrial membrane and an autophagosome membrane during mitophagy.”
- database_cross_reference “PMID:33138913”

mitochondrion-endoplasmic reticulum membrane tether activity definition “The binding activity of a molecule that brings together a mitochondrion and an ER membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.”
- database_cross_reference “PMID:27875684”
- database_cross_reference “PMID:19556461”

mitochondrion-endoplasmic reticulum membrane tether activity term tracker item “https://github.com/geneontology/go-ontology/issues/31866”^^anyURI
mitochondrion-endoplasmic reticulum membrane tether activity definition “The binding activity of a molecule that brings together a mitochondrial outer membrane and an ER membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.”
- database_cross_reference “PMID:27875684”
- database_cross_reference “PMID:19556461”

mitochondrion-plasma membrane adaptor activity definition “The binding activity of a molecule that brings together a mitochondrion and a plasma membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.”
- database_cross_reference “PMID:31582398”
mitochondrion-plasma membrane adaptor activity SubClassOf protein-membrane adaptor activity

mitochondrion-plasma membrane adaptor activity term tracker item “https://github.com/geneontology/go-ontology/issues/31866”^^anyURI
mitochondrion-plasma membrane adaptor activity definition “The binding activity of a molecule that brings together a mitochondrial outer membrane and a plasma membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.”
- database_cross_reference “PMID:31582398”
mitochondrion-plasma membrane adaptor activity SubClassOf membrane-membrane adaptor activity

nitric oxide dioxygenase [NAD(P)H] activity label “nitric oxide dioxygenase NAD(P)H activity”

nitric oxide dioxygenase [NAD(P)H] activity label “nitric oxide dioxygenase [NAD(P)H] activity”

obsolete 4-hydroxybutyrate CoA-transferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/31862”^^anyURI
obsolete 4-hydroxybutyrate CoA-transferase activity term replaced by 4-hydroxybutanoyl-CoA dehydratase activity
obsolete 4-hydroxybutyrate CoA-transferase activity definition “OBSOLETE. Catalysis of the transfer of a coenzyme A (CoA) group to 4-hydroxybutyrate.”
- database_cross_reference “GOC:jl”
- database_cross_reference “PMID:25452282”
obsolete 4-hydroxybutyrate CoA-transferase activity deprecated true
obsolete 4-hydroxybutyrate CoA-transferase activity comment “This term was obsoleted because it represents the same activity as 4-hydroxybutanoyl-CoA dehydratase activity ; GO:0043721. The term was incorrectly defined; the paper cited describes dehydration of 4-hydroxybutyryl-CoA to crotonyl-CoA ((2E)-butenoyl-CoA).”
obsolete 4-hydroxybutyrate CoA-transferase activity label “obsolete 4-hydroxybutyrate CoA-transferase activity”

obsolete C-acyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/31814”^^anyURI
obsolete C-acyltransferase activity term replaced by acyltransferase activity, transferring groups other than amino-acyl groups
obsolete C-acyltransferase activity definition “OBSOLETE. Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule.”
- database_cross_reference “GOC:ai”
obsolete C-acyltransferase activity deprecated true
obsolete C-acyltransferase activity comment “This term was obsoleted because it represents an unnecessary grouping class that lacks an EC cross-reference and leads to misclassification of children.”
obsolete C-acyltransferase activity label “obsolete C-acyltransferase activity”

obsolete GABA metabolic process definition “The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.”
- database_cross_reference “ISBN:0198506732”
obsolete GABA metabolic process comment “See also the biological process term ‘neurotransmitter metabolic process ; GO:0042133’.”
obsolete GABA metabolic process label “GABA metabolic process”
obsolete GABA metabolic process SubClassOf monocarboxylic acid metabolic process
obsolete GABA metabolic process SubClassOf non-proteinogenic amino acid metabolic process

obsolete GABA metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31172”^^anyURI
obsolete GABA metabolic process consider GABA biosynthetic process
obsolete GABA metabolic process consider GABA catabolic process
obsolete GABA metabolic process definition “OBSOLETE. The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.”
- database_cross_reference “ISBN:0198506732”
obsolete GABA metabolic process deprecated true
obsolete GABA metabolic process comment “This term was obsoleted because it is an unnecessary grouping term.”
obsolete GABA metabolic process label “obsolete GABA metabolic process”

obsolete L-dopa biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/31703”^^anyURI
obsolete L-dopa biosynthetic process definition “OBSOLETE. The chemical reactions and pathways resulting in the formation of L-dopa.”
- database_cross_reference “GOC:bf”
- database_cross_reference “PMID:8822146”
- database_cross_reference “GOC:PARL”
- database_cross_reference “GOC:TermGenie”
- database_cross_reference “GO_REF:0000068”
obsolete L-dopa biosynthetic process deprecated true
obsolete L-dopa biosynthetic process comment “This term was obsoleted because there is no evidence that this process exists.”
obsolete L-dopa biosynthetic process label “obsolete L-dopa biosynthetic process”

obsolete L-dopa metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31703”^^anyURI
obsolete L-dopa metabolic process term replaced by L-dopa catabolic process
obsolete L-dopa metabolic process definition “OBSOLETE. The chemical reactions and pathways involving L-dopa.”
- database_cross_reference “GOC:bf”
- database_cross_reference “PMID:8822146”
- database_cross_reference “GOC:PARL”
- database_cross_reference “GOC:TermGenie”
- database_cross_reference “GO_REF:0000068”
obsolete L-dopa metabolic process deprecated true
obsolete L-dopa metabolic process comment “This term was obsoleted because there is no evidence that this process exists; L-dopa metabolism has been used in the literature to mean L-dopa degradation.”
obsolete L-dopa metabolic process label “obsolete L-dopa metabolic process”

obsolete L-kynurenine catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31588”^^anyURI
obsolete L-kynurenine catabolic process definition “OBSOLETE. The chemical reactions and pathways resulting in the breakdown of L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).”
- database_cross_reference “GOC:yaf”
obsolete L-kynurenine catabolic process deprecated true
obsolete L-kynurenine catabolic process comment “This term was obsoleted because there is no evidence that this compound is specifically degraded.”
obsolete L-kynurenine catabolic process label “obsolete L-kynurenine catabolic process”

obsolete N-acyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/31814”^^anyURI
obsolete N-acyltransferase activity term replaced by acyltransferase activity, transferring groups other than amino-acyl groups
obsolete N-acyltransferase activity definition “OBSOLETE. Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule.”
- database_cross_reference “GOC:ai”
obsolete N-acyltransferase activity deprecated true
obsolete N-acyltransferase activity comment “This term was obsoleted because it represents an unnecessary grouping class that lacks an EC cross-reference and leads to misclassification of children.”
obsolete N-acyltransferase activity label “obsolete N-acyltransferase activity”

obsolete O-acyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/31814”^^anyURI
obsolete O-acyltransferase activity term replaced by acyltransferase activity, transferring groups other than amino-acyl groups
obsolete O-acyltransferase activity definition “OBSOLETE. Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule.”
- database_cross_reference “GOC:ai”
obsolete O-acyltransferase activity deprecated true
obsolete O-acyltransferase activity comment “This term was obsoleted because it represents an unnecessary grouping class that lacks an EC cross-reference and leads to misclassification of children.”
obsolete O-acyltransferase activity label “obsolete O-acyltransferase activity”

obsolete S-acyltransferase activity term tracker item “https://github.com/geneontology/go-ontology/issues/31814”^^anyURI
obsolete S-acyltransferase activity term replaced by acyltransferase activity, transferring groups other than amino-acyl groups
obsolete S-acyltransferase activity definition “OBSOLETE. Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule.”
- database_cross_reference “GOC:ai”
obsolete S-acyltransferase activity deprecated true
obsolete S-acyltransferase activity comment “This term was obsoleted because it represents an unnecessary grouping class that lacks an EC cross-reference and leads to misclassification of children.”
obsolete S-acyltransferase activity label “obsolete S-acyltransferase activity”

obsolete acetoacetic acid biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/31806”^^anyURI
obsolete acetoacetic acid biosynthetic process term replaced by ketone body biosynthetic process
obsolete acetoacetic acid biosynthetic process definition “OBSOLETE. The chemical reactions and pathways resulting in the formation of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH.”
- database_cross_reference “GOC:jl”
obsolete acetoacetic acid biosynthetic process deprecated true
obsolete acetoacetic acid biosynthetic process comment “This term was obsoleted because it represents a specific substrate of ketone body biosynthetic process ; GO:0046951.”
obsolete acetoacetic acid biosynthetic process label “obsolete acetoacetic acid biosynthetic process”

obsolete acetoacetic acid catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31806”^^anyURI
obsolete acetoacetic acid catabolic process term replaced by ketone body catabolic process
obsolete acetoacetic acid catabolic process definition “OBSOLETE. The chemical reactions and pathways resulting in the breakdown of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH.”
- database_cross_reference “GOC:jl”
obsolete acetoacetic acid catabolic process deprecated true
obsolete acetoacetic acid catabolic process comment “This term was obsoleted because it represents a specific substrate of ketone body catabolic process ; GO:0046952.”
obsolete acetoacetic acid catabolic process label “obsolete acetoacetic acid catabolic process”

obsolete acetoacetic acid metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31806”^^anyURI
obsolete acetoacetic acid metabolic process definition “OBSOLETE. The chemical reactions and pathways involving acetoacetic acid, 3-oxobutanoic acid; the empirical formula is C4H6O3 or CH3COCH2COOH.”
- database_cross_reference “Wikipedia:Acetoacetic_acid”
obsolete acetoacetic acid metabolic process deprecated true
obsolete acetoacetic acid metabolic process comment “This term was obsoleted because it is an unnecessary grouping term.”
obsolete acetoacetic acid metabolic process label “obsolete acetoacetic acid metabolic process”

obsolete activation of bipolar cell growth term tracker item “https://github.com/geneontology/go-ontology/issues/31746”^^anyURI
obsolete activation of bipolar cell growth term replaced by positive regulation of bipolar cell growth
obsolete activation of bipolar cell growth definition “OBSOLETE. Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell.”
- database_cross_reference “GOC:ai”
obsolete activation of bipolar cell growth deprecated true
obsolete activation of bipolar cell growth comment “This term was obsoleted because it represented the same process as its parent, positive regulation of bipolar cell growth ; GO:0051518.”
obsolete activation of bipolar cell growth label “obsolete activation of bipolar cell growth”

obsolete amino acid catabolic process to alcohol via Ehrlich pathway definition “The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete amino acid catabolic process to alcohol via Ehrlich pathway label “amino acid catabolic process to alcohol via Ehrlich pathway”
obsolete amino acid catabolic process to alcohol via Ehrlich pathway SubClassOf obsolete amino acid catabolic process via Ehrlich pathway
obsolete amino acid catabolic process to alcohol via Ehrlich pathway SubClassOf alcohol biosynthetic process

obsolete amino acid catabolic process to alcohol via Ehrlich pathway term tracker item “https://github.com/geneontology/go-ontology/issues/31839”^^anyURI
obsolete amino acid catabolic process to alcohol via Ehrlich pathway definition “OBSOLETE. The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete amino acid catabolic process to alcohol via Ehrlich pathway deprecated true
obsolete amino acid catabolic process to alcohol via Ehrlich pathway comment “This term was obsoleted because it represents multiple specific pathways. Consider specific amino acid catabolic processes.”
obsolete amino acid catabolic process to alcohol via Ehrlich pathway label “obsolete amino acid catabolic process to alcohol via Ehrlich pathway”

obsolete amino acid catabolic process to carboxylic acid via Ehrlich pathway definition “The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete amino acid catabolic process to carboxylic acid via Ehrlich pathway label “amino acid catabolic process to carboxylic acid via Ehrlich pathway”
obsolete amino acid catabolic process to carboxylic acid via Ehrlich pathway SubClassOf obsolete amino acid catabolic process via Ehrlich pathway
obsolete amino acid catabolic process to carboxylic acid via Ehrlich pathway SubClassOf carboxylic acid biosynthetic process

obsolete amino acid catabolic process to carboxylic acid via Ehrlich pathway term tracker item “https://github.com/geneontology/go-ontology/issues/31839”^^anyURI
obsolete amino acid catabolic process to carboxylic acid via Ehrlich pathway definition “OBSOLETE. The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete amino acid catabolic process to carboxylic acid via Ehrlich pathway deprecated true
obsolete amino acid catabolic process to carboxylic acid via Ehrlich pathway comment “This term was obsoleted because it represents multiple specific pathways. Consider specific amino acid catabolic processes.”
obsolete amino acid catabolic process to carboxylic acid via Ehrlich pathway label “obsolete amino acid catabolic process to carboxylic acid via Ehrlich pathway”

obsolete amino acid catabolic process via Ehrlich pathway definition “The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete amino acid catabolic process via Ehrlich pathway label “amino acid catabolic process via Ehrlich pathway”
obsolete amino acid catabolic process via Ehrlich pathway SubClassOf amino acid catabolic process

obsolete amino acid catabolic process via Ehrlich pathway term tracker item “https://github.com/geneontology/go-ontology/issues/31839”^^anyURI
obsolete amino acid catabolic process via Ehrlich pathway definition “OBSOLETE. The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete amino acid catabolic process via Ehrlich pathway deprecated true
obsolete amino acid catabolic process via Ehrlich pathway comment “This term was obsoleted because it represents multiple specific pathways. Consider specific amino acid catabolic processes.”
obsolete amino acid catabolic process via Ehrlich pathway label “obsolete amino acid catabolic process via Ehrlich pathway”

obsolete aromatic amino acid family catabolic process to alcohol via Ehrlich pathway definition “The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete aromatic amino acid family catabolic process to alcohol via Ehrlich pathway label “aromatic amino acid family catabolic process to alcohol via Ehrlich pathway”
obsolete aromatic amino acid family catabolic process to alcohol via Ehrlich pathway SubClassOf obsolete amino acid catabolic process to alcohol via Ehrlich pathway
obsolete aromatic amino acid family catabolic process to alcohol via Ehrlich pathway SubClassOf aromatic amino acid family catabolic process

obsolete aromatic amino acid family catabolic process to alcohol via Ehrlich pathway term tracker item “https://github.com/geneontology/go-ontology/issues/31839”^^anyURI
obsolete aromatic amino acid family catabolic process to alcohol via Ehrlich pathway consider L-phenylalanine catabolic process
obsolete aromatic amino acid family catabolic process to alcohol via Ehrlich pathway consider L-tryptophan catabolic process
obsolete aromatic amino acid family catabolic process to alcohol via Ehrlich pathway consider L-tyrosine catabolic process
obsolete aromatic amino acid family catabolic process to alcohol via Ehrlich pathway definition “OBSOLETE. The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete aromatic amino acid family catabolic process to alcohol via Ehrlich pathway deprecated true
obsolete aromatic amino acid family catabolic process to alcohol via Ehrlich pathway comment “This term was obsoleted because it represents multiple specific pathways. Consider specific amino acid catabolic processes.”
obsolete aromatic amino acid family catabolic process to alcohol via Ehrlich pathway label “obsolete aromatic amino acid family catabolic process to alcohol via Ehrlich pathway”

obsolete aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway definition “The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway label “aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway”
obsolete aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway SubClassOf obsolete amino acid catabolic process to carboxylic acid via Ehrlich pathway
obsolete aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway SubClassOf aromatic amino acid family catabolic process

obsolete aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway term tracker item “https://github.com/geneontology/go-ontology/issues/31839”^^anyURI
obsolete aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway consider L-phenylalanine catabolic process
obsolete aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway consider L-tryptophan catabolic process
obsolete aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway consider L-tyrosine catabolic process
obsolete aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway definition “OBSOLETE. The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway deprecated true
obsolete aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway comment “This term was obsoleted because it represents multiple specific pathways. Consider specific amino acid catabolic processes.”
obsolete aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway label “obsolete aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway”

obsolete beta-alanine metabolic process database_cross_reference “Wikipedia:Beta-alanine”
obsolete beta-alanine metabolic process definition “The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.”
- database_cross_reference “GOC:jl”
- database_cross_reference “ISBN:0198506732”
obsolete beta-alanine metabolic process label “beta-alanine metabolic process”
obsolete beta-alanine metabolic process SubClassOf non-proteinogenic amino acid metabolic process

obsolete beta-alanine metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31172”^^anyURI
obsolete beta-alanine metabolic process consider beta-alanine biosynthetic process
obsolete beta-alanine metabolic process consider beta-alanine catabolic process
obsolete beta-alanine metabolic process definition “OBSOLETE. The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.”
- database_cross_reference “GOC:jl”
- database_cross_reference “ISBN:0198506732”
obsolete beta-alanine metabolic process deprecated true
obsolete beta-alanine metabolic process comment “This term was obsoleted because it is an unnecessary grouping term.”
obsolete beta-alanine metabolic process label “obsolete beta-alanine metabolic process”

obsolete branched-chain amino acid catabolic process to alcohol via Ehrlich pathway definition “The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete branched-chain amino acid catabolic process to alcohol via Ehrlich pathway label “branched-chain amino acid catabolic process to alcohol via Ehrlich pathway”
obsolete branched-chain amino acid catabolic process to alcohol via Ehrlich pathway SubClassOf obsolete amino acid catabolic process to alcohol via Ehrlich pathway
obsolete branched-chain amino acid catabolic process to alcohol via Ehrlich pathway SubClassOf branched-chain amino acid catabolic process

obsolete branched-chain amino acid catabolic process to alcohol via Ehrlich pathway term tracker item “https://github.com/geneontology/go-ontology/issues/31839”^^anyURI
obsolete branched-chain amino acid catabolic process to alcohol via Ehrlich pathway consider L-isoleucine catabolic process
obsolete branched-chain amino acid catabolic process to alcohol via Ehrlich pathway consider L-leucine catabolic process
obsolete branched-chain amino acid catabolic process to alcohol via Ehrlich pathway consider L-valine catabolic process
obsolete branched-chain amino acid catabolic process to alcohol via Ehrlich pathway definition “OBSOLETE. The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete branched-chain amino acid catabolic process to alcohol via Ehrlich pathway deprecated true
obsolete branched-chain amino acid catabolic process to alcohol via Ehrlich pathway comment “This term was obsoleted because it represents multiple specific pathways. Consider specific amino acid catabolic processes.”
obsolete branched-chain amino acid catabolic process to alcohol via Ehrlich pathway label “obsolete branched-chain amino acid catabolic process to alcohol via Ehrlich pathway”

obsolete branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway definition “The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanoate, 2-methylbutanoate, or 2-methylpropanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway label “branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway”
obsolete branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway SubClassOf obsolete amino acid catabolic process to carboxylic acid via Ehrlich pathway
obsolete branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway SubClassOf branched-chain amino acid catabolic process

obsolete branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway term tracker item “https://github.com/geneontology/go-ontology/issues/31839”^^anyURI
obsolete branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway consider L-isoleucine catabolic process
obsolete branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway consider L-leucine catabolic process
obsolete branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway consider L-valine catabolic process
obsolete branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway definition “OBSOLETE. The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanoate, 2-methylbutanoate, or 2-methylpropanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.”
- database_cross_reference “GOC:krc”
- database_cross_reference “PMID:18281432”
obsolete branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway deprecated true
obsolete branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway comment “This term was obsoleted because it represents multiple specific pathways. Consider specific amino acid catabolic processes.”
obsolete branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway label “obsolete branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway”

obsolete catecholamine transport definition “The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.”
- database_cross_reference “GOC:ai”
- database_cross_reference “ISBN:0198506732”
obsolete catecholamine transport label “catecholamine transport”
obsolete catecholamine transport SubClassOf obsolete monoamine transport
obsolete catecholamine transport SubClassOf organic hydroxy compound transport

obsolete catecholamine transport term tracker item “https://github.com/geneontology/go-ontology/issues/31143”^^anyURI
obsolete catecholamine transport definition “OBSOLETE. The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.”
- database_cross_reference “GOC:ai”
- database_cross_reference “ISBN:0198506732”
obsolete catecholamine transport deprecated true
obsolete catecholamine transport comment “The reason for obsoletion is that this is an unnecessary grouping term and annotations should be made to more mechanism/location specific terms.”
obsolete catecholamine transport label “obsolete catecholamine transport”

obsolete denatured protein binding definition “Binding to a denatured protein.”
- database_cross_reference “GOC:mlg”
obsolete denatured protein binding comment “Note that this term should not be confused with ‘unfolded protein binding ; GO:0051082’, which usually refers to proteins that have not yet folded into their active states. Denatured proteins once were in their correct functional conformations, but have become incorrectly folded, and often form aggregates.”
obsolete denatured protein binding label “denatured protein binding”
obsolete denatured protein binding SubClassOf protein binding

obsolete dopamine transport definition “The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.”
- database_cross_reference “GOC:ai”
obsolete dopamine transport label “dopamine transport”
obsolete dopamine transport SubClassOf obsolete catecholamine transport

obsolete dopamine transport term tracker item “https://github.com/geneontology/go-ontology/issues/31143”^^anyURI
obsolete dopamine transport definition “OBSOLETE. The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.”
- database_cross_reference “GOC:ai”
obsolete dopamine transport deprecated true
obsolete dopamine transport comment “The reason for obsoletion is that this is an unnecessary grouping term and annotations should be made to more mechanism/location specific terms.”
obsolete dopamine transport label “obsolete dopamine transport”

obsolete endocrine hormone secretion term tracker item “https://github.com/geneontology/go-ontology/issues/17084”^^anyURI
obsolete endocrine hormone secretion term replaced by hormone secretion
obsolete endocrine hormone secretion definition “OBSOLETE. The regulated release of a hormone into the circulatory system.”
- database_cross_reference “GOC:dph”
obsolete endocrine hormone secretion deprecated true
obsolete endocrine hormone secretion comment “The reason for obsoletion is that this term represents fake precision. The distinction between endocrine and other modes of hormone dispersal (paracrine, autocrine) is not always clear-cut, and this term was unevenly used relative to its parent.”
obsolete endocrine hormone secretion label “obsolete endocrine hormone secretion”

obsolete epinephrine transport term tracker item “https://github.com/geneontology/go-ontology/issues/31143”^^anyURI
obsolete epinephrine transport definition “OBSOLETE. The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.”
- database_cross_reference “GOC:jid”
obsolete epinephrine transport deprecated true
obsolete epinephrine transport comment “The reason for obsoletion is that this is an unnecessary grouping term and annotations should be made to more mechanism/location specific terms.”
obsolete epinephrine transport label “obsolete epinephrine transport”

obsolete exocytic insertion of neurotransmitter receptor to plasma membrane term tracker item “https://github.com/geneontology/go-ontology/issues/31869”^^anyURI
obsolete exocytic insertion of neurotransmitter receptor to plasma membrane definition “OBSOLETE. The exocytic fusion of neurotransmitter receptor-containing vesicles with plasma membrane, resulting in the integration of neurotransmitter receptors into the plasma membrane. This process includes tethering and docking steps that prepare vesicles for fusion.”
- database_cross_reference “PMID:19503082”
- database_cross_reference “GOC:bc”
- database_cross_reference “GOC:aruk”
obsolete exocytic insertion of neurotransmitter receptor to plasma membrane deprecated true
obsolete exocytic insertion of neurotransmitter receptor to plasma membrane comment “The reason for obsoletion is that the meaning of the term is ambiguous. It was placed under both tethering and docking involved in exocytosis, but it is unclear which part of exocytosis it refers to, and it has not been used.”
obsolete exocytic insertion of neurotransmitter receptor to plasma membrane label “obsolete exocytic insertion of neurotransmitter receptor to plasma membrane”

obsolete glucarate biosynthetic process definition “The chemical reactions and pathways resulting in the formation of glucarate, the anion of glucaric acid.”
- database_cross_reference “ISBN:0198506732”
obsolete glucarate biosynthetic process label “glucarate biosynthetic process”
obsolete glucarate biosynthetic process SubClassOf aldaric acid biosynthetic process

obsolete glucarate biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/27059”^^anyURI
obsolete glucarate biosynthetic process term replaced by D-glucarate biosynthetic process
obsolete glucarate biosynthetic process definition “OBSOLETE. The chemical reactions and pathways resulting in the formation of glucarate, the anion of glucaric acid.”
- database_cross_reference “ISBN:0198506732”
obsolete glucarate biosynthetic process deprecated true
obsolete glucarate biosynthetic process comment “This term was obsoleted because it represents the same process as D-glucarate biosynthetic process ; GO:0042837.”
obsolete glucarate biosynthetic process label “obsolete glucarate biosynthetic process”

obsolete induction of conjugation with cellular fusion definition “The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types.”
- database_cross_reference “GOC:dph”
- database_cross_reference “GOC:tb”
obsolete induction of conjugation with cellular fusion label “induction of conjugation with cellular fusion”
obsolete induction of conjugation with cellular fusion SubClassOf positive regulation of conjugation with cellular fusion

obsolete induction of conjugation with cellular fusion term tracker item “https://github.com/geneontology/go-ontology/issues/31335”^^anyURI
obsolete induction of conjugation with cellular fusion term replaced by positive regulation of conjugation with cellular fusion
obsolete induction of conjugation with cellular fusion definition “OBSOLETE. The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types.”
- database_cross_reference “GOC:dph”
- database_cross_reference “GOC:tb”
obsolete induction of conjugation with cellular fusion deprecated true
obsolete induction of conjugation with cellular fusion comment “This term was obsoleted because it is a pre-composed term that should be represented as a GO-CAM model.”
obsolete induction of conjugation with cellular fusion label “obsolete induction of conjugation with cellular fusion”

obsolete ketone body metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31806”^^anyURI
obsolete ketone body metabolic process definition “OBSOLETE. The chemical reactions and pathways involving ketone body.”
- database_cross_reference “GOC:TermGenie”
- database_cross_reference “GOC:pr”
obsolete ketone body metabolic process deprecated true
obsolete ketone body metabolic process comment “This term was obsoleted because it is an unnecessary grouping term.”
obsolete ketone body metabolic process label “obsolete ketone body metabolic process”

obsolete monoamine transport definition “The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.”
- database_cross_reference “GOC:mah”
obsolete monoamine transport label “monoamine transport”
obsolete monoamine transport SubClassOf nitrogen compound transport

obsolete monoamine transport term tracker item “https://github.com/geneontology/go-ontology/issues/31143”^^anyURI
obsolete monoamine transport definition “OBSOLETE. The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.”
- database_cross_reference “GOC:mah”
obsolete monoamine transport deprecated true
obsolete monoamine transport comment “The reason for obsoletion is that this is an unnecessary grouping term and annotations should be made to more mechanism/location specific terms.”
obsolete monoamine transport label “obsolete monoamine transport”

obsolete nitric oxide mediated signal transduction has_exact_synonym “NO mediated signal transduction”
obsolete nitric oxide mediated signal transduction has_exact_synonym “NO-mediated signal transduction”
obsolete nitric oxide mediated signal transduction has_exact_synonym “nitric oxide-mediated signal transduction”
obsolete nitric oxide mediated signal transduction has_exact_synonym “nitric oxide signaling”
- database_cross_reference “GOC:bf”
obsolete nitric oxide mediated signal transduction definition “An intracellular signaling cassette that starts with production of nitric oxide, detection by receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and ends with the activation of downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms.”
- database_cross_reference “GOC:jl”
- database_cross_reference “PMID:21549190”
obsolete nitric oxide mediated signal transduction label “nitric oxide mediated signal transduction”
obsolete nitric oxide mediated signal transduction SubClassOf intracellular signaling cassette

obsolete nitric oxide mediated signal transduction term tracker item “https://github.com/geneontology/go-ontology/issues/26613”^^anyURI
obsolete nitric oxide mediated signal transduction term replaced by nitric oxide-cGMP-mediated signaling
obsolete nitric oxide mediated signal transduction definition “OBSOLETE. An intracellular signaling cassette that starts with production of nitric oxide, detection by receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and ends with the activation of downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms.”
- database_cross_reference “GOC:jl”
- database_cross_reference “PMID:21549190”
obsolete nitric oxide mediated signal transduction deprecated true
obsolete nitric oxide mediated signal transduction comment “The reason for obsoletion is that this term has been inconsistently used and NO signaling proceeds via cGMP, so the more specific replacement term is preferred.”
obsolete nitric oxide mediated signal transduction label “obsolete nitric oxide mediated signal transduction”

obsolete norepinephrine transport has_exact_synonym “levarterenol transport”
obsolete norepinephrine transport has_exact_synonym “noradrenaline transport”
obsolete norepinephrine transport definition “The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.”
- database_cross_reference “GOC:ai”
- database_cross_reference “ISBN:0198506732”
obsolete norepinephrine transport label “norepinephrine transport”
obsolete norepinephrine transport SubClassOf obsolete organic cation transport
obsolete norepinephrine transport SubClassOf obsolete catecholamine transport

obsolete norepinephrine transport term tracker item “https://github.com/geneontology/go-ontology/issues/31143”^^anyURI
obsolete norepinephrine transport definition “OBSOLETE. The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.”
- database_cross_reference “GOC:ai”
- database_cross_reference “ISBN:0198506732”
obsolete norepinephrine transport deprecated true
obsolete norepinephrine transport comment “The reason for obsoletion is that this is an unnecessary grouping term and annotations should be made to more mechanism/location specific terms.”
obsolete norepinephrine transport label “obsolete norepinephrine transport”

obsolete old cell tip after activation of bipolar cell growth definition “A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs, which is part of a cell that has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.”
- database_cross_reference “GOC:mah”
- database_cross_reference “GOC:expert_jd”
obsolete old cell tip after activation of bipolar cell growth label “old cell tip after activation of bipolar cell growth”
obsolete old cell tip after activation of bipolar cell growth SubClassOf old growing cell tip

obsolete old cell tip after activation of bipolar cell growth term tracker item “https://github.com/geneontology/go-ontology/issues/31746”^^anyURI
obsolete old cell tip after activation of bipolar cell growth term replaced by old growing cell tip
obsolete old cell tip after activation of bipolar cell growth definition “OBSOLETE. A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs, which is part of a cell that has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.”
- database_cross_reference “GOC:mah”
- database_cross_reference “GOC:expert_jd”
obsolete old cell tip after activation of bipolar cell growth deprecated true
obsolete old cell tip after activation of bipolar cell growth comment “This term was obsoleted because the parent process, activation of bipolar cell growth, GO:0051519, was obsoleted.”
obsolete old cell tip after activation of bipolar cell growth label “obsolete old cell tip after activation of bipolar cell growth”

obsolete organic acid biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/31816”^^anyURI
obsolete organic acid biosynthetic process term replaced by metabolic process
obsolete organic acid biosynthetic process definition “OBSOLETE. The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.”
- database_cross_reference “ISBN:0198506732”
obsolete organic acid biosynthetic process deprecated true
obsolete organic acid biosynthetic process comment “The reason for obsoletion is that this term was an unnecessary grouping term.”
obsolete organic acid biosynthetic process label “obsolete organic acid biosynthetic process”

obsolete organic acid catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31816”^^anyURI
obsolete organic acid catabolic process term replaced by metabolic process
obsolete organic acid catabolic process definition “OBSOLETE. The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.”
- database_cross_reference “ISBN:0198506732”
obsolete organic acid catabolic process deprecated true
obsolete organic acid catabolic process comment “The reason for obsoletion is that this term was an unnecessary grouping term.”
obsolete organic acid catabolic process label “obsolete organic acid catabolic process”

obsolete organic acid metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31816”^^anyURI
obsolete organic acid metabolic process term replaced by metabolic process
obsolete organic acid metabolic process definition “OBSOLETE. The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.”
- database_cross_reference “ISBN:0198506732”
obsolete organic acid metabolic process deprecated true
obsolete organic acid metabolic process comment “The reason for obsoletion is that this term was an unnecessary grouping term.”
obsolete organic acid metabolic process label “obsolete organic acid metabolic process”

obsolete organic anion transport definition “The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.”
- database_cross_reference “GOC:krc”
- database_cross_reference “GOC:ai”
obsolete organic anion transport label “organic anion transport”
obsolete organic anion transport SubClassOf transport

obsolete organic anion transport term tracker item “https://github.com/geneontology/go-ontology/issues/30715”^^anyURI
obsolete organic anion transport term replaced by transmembrane transport
obsolete organic anion transport definition “OBSOLETE. The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.”
- database_cross_reference “GOC:krc”
- database_cross_reference “GOC:ai”
obsolete organic anion transport deprecated true
obsolete organic anion transport comment “The reason for obsoletion is that this term was an unnecessary grouping term.”
obsolete organic anion transport label “obsolete organic anion transport”

obsolete organic cation transport definition “The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage.”
- database_cross_reference “GOC:ai”
obsolete organic cation transport label “organic cation transport”
obsolete organic cation transport SubClassOf transport

obsolete organic cation transport term tracker item “https://github.com/geneontology/go-ontology/issues/30715”^^anyURI
obsolete organic cation transport term replaced by transmembrane transport
obsolete organic cation transport definition “OBSOLETE. The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage.”
- database_cross_reference “GOC:ai”
obsolete organic cation transport deprecated true
obsolete organic cation transport comment “The reason for obsoletion is that this term was an unnecessary grouping term.”
obsolete organic cation transport label “obsolete organic cation transport”

obsolete para-aminobenzoic acid metabolic process definition “The chemical reactions and pathways involving para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.”
- database_cross_reference “PMID:11960743”
obsolete para-aminobenzoic acid metabolic process label “para-aminobenzoic acid metabolic process”
obsolete para-aminobenzoic acid metabolic process SubClassOf aromatic amino acid metabolic process
obsolete para-aminobenzoic acid metabolic process SubClassOf monocarboxylic acid metabolic process
obsolete para-aminobenzoic acid metabolic process SubClassOf benzene-containing compound metabolic process

obsolete para-aminobenzoic acid metabolic process consider 4-aminobenzoate biosynthetic process
obsolete para-aminobenzoic acid metabolic process definition “OBSOLETE. The chemical reactions and pathways involving para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.”
- database_cross_reference “PMID:11960743”
obsolete para-aminobenzoic acid metabolic process deprecated true
obsolete para-aminobenzoic acid metabolic process comment “This term was obsoleted because it is an unnecessary grouping term.”
obsolete para-aminobenzoic acid metabolic process label “obsolete para-aminobenzoic acid metabolic process”

obsolete protoporphyrinogen IX biosynthetic process from glutamate term tracker item “https://github.com/geneontology/go-ontology/issues/31788”^^anyURI
obsolete protoporphyrinogen IX biosynthetic process from glutamate definition “OBSOLETE. The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate.”
- database_cross_reference “PMID:32976912”
obsolete protoporphyrinogen IX biosynthetic process from glutamate deprecated true
obsolete protoporphyrinogen IX biosynthetic process from glutamate comment “This term was obsoleted because protoporphyrinogen IX is an intermediate in heme/chlorophyll/uroporphyrinogen biosynthesis.”
obsolete protoporphyrinogen IX biosynthetic process from glutamate label “obsolete protoporphyrinogen IX biosynthetic process from glutamate”

obsolete protoporphyrinogen IX metabolic process definition “The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.”
- database_cross_reference “ISBN:0198506732”
obsolete protoporphyrinogen IX metabolic process comment “See also the molecular function term ‘ferrochelatase activity ; GO:0004325’.”
obsolete protoporphyrinogen IX metabolic process label “protoporphyrinogen IX metabolic process”
obsolete protoporphyrinogen IX metabolic process SubClassOf porphyrin-containing compound metabolic process

obsolete protoporphyrinogen IX metabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31788”^^anyURI
obsolete protoporphyrinogen IX metabolic process definition “OBSOLETE. The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.”
- database_cross_reference “ISBN:0198506732”
obsolete protoporphyrinogen IX metabolic process deprecated true
obsolete protoporphyrinogen IX metabolic process comment “This term was obsoleted because protoporphyrinogen IX is an intermediate in heme/chlorophyll/uroporphyrinogen biosynthesis.”
obsolete protoporphyrinogen IX metabolic process label “obsolete protoporphyrinogen IX metabolic process”

obsolete putrescine biosynthetic process from arginine via N-carbamoylputrescine database_cross_reference “MetaCyc:PWY-43”
obsolete putrescine biosynthetic process from arginine via N-carbamoylputrescine definition “The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine, via the intermediate N-carbamoylputrescine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in two single enzymatic steps.”
- database_cross_reference “MetaCyc:PWY-43”
- database_cross_reference “GOC:mah”
obsolete putrescine biosynthetic process from arginine via N-carbamoylputrescine label “putrescine biosynthetic process from arginine via N-carbamoylputrescine”
obsolete putrescine biosynthetic process from arginine via N-carbamoylputrescine SubClassOf obsolete putrescine biosynthetic process from arginine

obsolete regulation of L-dopa biosynthetic process term tracker item “https://github.com/geneontology/go-ontology/issues/31703”^^anyURI
obsolete regulation of L-dopa biosynthetic process definition “OBSOLETE. Any process that modulates the frequency, rate or extent of L-dopa biosynthetic process.”
- database_cross_reference “GOC:bf”
- database_cross_reference “GOC:PARL”
- database_cross_reference “GOC:TermGenie”
- database_cross_reference “GO_REF:0000058”
obsolete regulation of L-dopa biosynthetic process deprecated true
obsolete regulation of L-dopa biosynthetic process comment “This term was obsoleted because there is no evidence that this process exists.”
obsolete regulation of L-dopa biosynthetic process label “obsolete regulation of L-dopa biosynthetic process”

obsolete regulation of nitric oxide mediated signal transduction term tracker item “https://github.com/geneontology/go-ontology/issues/26613”^^anyURI
obsolete regulation of nitric oxide mediated signal transduction term replaced by regulation of nitric oxide-cGMP mediated signal transduction
obsolete regulation of nitric oxide mediated signal transduction definition “OBSOLETE. Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO).”
- database_cross_reference “GOC:dph”
- database_cross_reference “GOC:tb”
- database_cross_reference “GOC:BHF”
obsolete regulation of nitric oxide mediated signal transduction deprecated true
obsolete regulation of nitric oxide mediated signal transduction comment “The reason for obsoletion is that this term has been inconsistently used and NO signaling proceeds via cGMP, so the more specific replacement term is preferred.”
obsolete regulation of nitric oxide mediated signal transduction label “obsolete regulation of nitric oxide mediated signal transduction”

obsolete serotonin biosynthetic process from L-tryptophan definition “The chemical reactions and pathways resulting in the formation from L-tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.”
- database_cross_reference “GOC:jl”
- database_cross_reference “PMID:30901029”
- database_cross_reference “PMID:35495641”
- database_cross_reference “ISBN:0198506732”
obsolete serotonin biosynthetic process from L-tryptophan label “serotonin biosynthetic process from L-tryptophan”
obsolete serotonin biosynthetic process from L-tryptophan SubClassOf L-tryptophan metabolic process
obsolete serotonin biosynthetic process from L-tryptophan SubClassOf serotonin biosynthetic process

obsolete serotonin biosynthetic process from L-tryptophan term replaced by serotonin biosynthetic process
obsolete serotonin biosynthetic process from L-tryptophan definition “OBSOLETE. The chemical reactions and pathways resulting in the formation from L-tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.”
- database_cross_reference “GOC:jl”
- database_cross_reference “PMID:30901029”
- database_cross_reference “PMID:35495641”
- database_cross_reference “ISBN:0198506732”
obsolete serotonin biosynthetic process from L-tryptophan deprecated true
obsolete serotonin biosynthetic process from L-tryptophan comment “The reason for obsoletion is that the term is too specific.”
obsolete serotonin biosynthetic process from L-tryptophan label “obsolete serotonin biosynthetic process from L-tryptophan”

obsolete serotonin transport definition “The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.”
- database_cross_reference “GOC:ai”
obsolete serotonin transport label “serotonin transport”
obsolete serotonin transport SubClassOf obsolete monoamine transport
obsolete serotonin transport SubClassOf organic hydroxy compound transport

obsolete serotonin transport term tracker item “https://github.com/geneontology/go-ontology/issues/31143”^^anyURI
obsolete serotonin transport definition “OBSOLETE. The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.”
- database_cross_reference “GOC:ai”
obsolete serotonin transport deprecated true
obsolete serotonin transport comment “The reason for obsoletion is that this is an unnecessary grouping term and annotations should be made to more mechanism/location specific terms.”
obsolete serotonin transport label “obsolete serotonin transport”

obsolete trimethylenediamine catabolic process term tracker item “https://github.com/geneontology/go-ontology/issues/31766”^^anyURI
obsolete trimethylenediamine catabolic process definition “OBSOLETE. The chemical reactions and pathways resulting in the breakdown of trimethylenediamine.”
- database_cross_reference “UniPathway:UPA00010”
- database_cross_reference “GOC:yaf”
- database_cross_reference “GOC:TermGenie”
obsolete trimethylenediamine catabolic process deprecated true
obsolete trimethylenediamine catabolic process comment “The reason for obsoletion is that this term was made in error.”
obsolete trimethylenediamine catabolic process label “obsolete trimethylenediamine catabolic process”

obsolete tubulin folding cofactor complex definition “A multimeric protein complex involved in tubulin alpha-beta-subunit folding assembly consisting of beta-tubulin-TFC-D, alpha-tubulin-TFC-E and TFC-C, through which tubulin subunit association and dimer release occur.”
- database_cross_reference “PMID:12445400”
- database_cross_reference “GOC:vw”
obsolete tubulin folding cofactor complex label “tubulin folding cofactor complex”
obsolete tubulin folding cofactor complex SubClassOf protein-containing complex

obsolete tubulin folding cofactor complex term tracker item “https://github.com/geneontology/go-ontology/issues/31828”^^anyURI
obsolete tubulin folding cofactor complex definition “OBSOLETE. A multimeric protein complex involved in tubulin alpha-beta-subunit folding assembly consisting of beta-tubulin-TFC-D, alpha-tubulin-TFC-E and TFC-C, through which tubulin subunit association and dimer release occur.”
- database_cross_reference “PMID:12445400”
- database_cross_reference “GOC:vw”
obsolete tubulin folding cofactor complex deprecated true
obsolete tubulin folding cofactor complex comment “This term was obsoleted because it was created by mistake; this is a pathway, not a complex.”
obsolete tubulin folding cofactor complex label “obsolete tubulin folding cofactor complex”

obsolete tyramine transport created by “dragon-ai-agent”
obsolete tyramine transport definition “The directed movement of tyramine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tyramine is a monoamine neurotransmitter occurring predominantly in invertebrates.”
- database_cross_reference “PMID:9870940”
- database_cross_reference “PMID:32305263”
- database_cross_reference “PMID:15849736”
obsolete tyramine transport label “tyramine transport”
obsolete tyramine transport SubClassOf obsolete monoamine transport
obsolete tyramine transport SubClassOf organic hydroxy compound transport

obsolete tyramine transport definition “OBSOLETE. The directed movement of tyramine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tyramine is a monoamine neurotransmitter occurring predominantly in invertebrates.”
- database_cross_reference “PMID:9870940”
- database_cross_reference “PMID:32305263”
- database_cross_reference “PMID:15849736”
obsolete tyramine transport deprecated true
obsolete tyramine transport comment “The reason for obsoletion is that this is an unnecessary grouping term and annotations should be made to more mechanism/location specific terms.”
obsolete tyramine transport label “obsolete tyramine transport”

obsolete unfolded protein binding term tracker item “https://github.com/geneontology/go-ontology/issues/30962”^^anyURI
obsolete unfolded protein binding consider protein folding chaperone
obsolete unfolded protein binding consider unfolded protein holdase activity
obsolete unfolded protein binding definition “OBSOLETE. Binding to an unfolded protein.”
- database_cross_reference “GOC:ai”
obsolete unfolded protein binding deprecated true
obsolete unfolded protein binding comment “The reason for obsoletion is that this binding term should be replaced by an activity term such as protein folding chaperone (GO:0044183) or unfolded protein holdase activity (GO:0140309).”
obsolete unfolded protein binding label “obsolete unfolded protein binding”

oxygen evolving activity relatedMatch RXN0-5265
oxygen evolving activity definition “Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.”
- database_cross_reference “GOC:kd”
- database_cross_reference “PMID:17091926”
- database_cross_reference “GOC:syr”
- database_cross_reference “PMID:7948862”
oxygen evolving activity SubClassOf oxidoreductase activity

oxygen evolving activity term tracker item “https://github.com/geneontology/go-ontology/issues/31592”^^anyURI
oxygen evolving activity definition “Catalysis of the reaction: 2 a plastoquinone + 4 hnu + 2 H2O = 2 a plastoquinol + O2. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants.”
- database_cross_reference “PMID:17091926”
- database_cross_reference “PMID:7948862”
- database_cross_reference “RHEA:36359”
oxygen evolving activity SubClassOf oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor

peroxisome-endoplasmic reticulum membrane tether activity definition “The binding activity of a molecule that brings together a peroxisome and an ER membrane, either via membrane lipid binding or by interacting with a membrane protein.”
- database_cross_reference “PMID:39271061”

peroxisome-endoplasmic reticulum membrane tether activity term tracker item “https://github.com/geneontology/go-ontology/issues/31866”^^anyURI
peroxisome-endoplasmic reticulum membrane tether activity definition “The binding activity of a molecule that brings together a peroxisome membrane and an ER membrane, either via membrane lipid binding or by interacting with a membrane protein.”
- database_cross_reference “PMID:39271061”

peroxisome-mitochondrion membrane tether activity definition “The binding activity of a molecule that brings together the peroxisome and the mitochondrial outer membrane, establishing the localization of the peroxisome close to the mitochondrion.”
- database_cross_reference “PMID:38669296”
- database_cross_reference “PMID:29720625”
peroxisome-mitochondrion membrane tether activity SubClassOf protein-membrane adaptor activity

peroxisome-mitochondrion membrane tether activity term tracker item “https://github.com/geneontology/go-ontology/issues/31866”^^anyURI
peroxisome-mitochondrion membrane tether activity definition “The binding activity of a molecule that brings together the peroxisome membrane and the mitochondrial outer membrane, establishing the localization of the peroxisome close to the mitochondrion.”
- database_cross_reference “PMID:38669296”
- database_cross_reference “PMID:29720625”
peroxisome-mitochondrion membrane tether activity SubClassOf membrane-membrane adaptor activity

phthalate 4,5-dioxygenase activity definition “Catalysis of the reaction: H+ + NADH + O2 + phthalate = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD+.”
- database_cross_reference “EC:1.14.12.7”
- database_cross_reference “RHEA:17489”

phthalate 4,5-dioxygenase activity definition “Catalysis of the reaction: phthalate + NADH + O2 + H+ = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD+.”
- database_cross_reference “RHEA:17489”

podosome term tracker item “https://github.com/geneontology/go-ontology/issues/20443”^^anyURI
podosome SubClassOf actin-based cell projection

propionate CoA-transferase activity definition “Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA.”
- database_cross_reference “EC:2.8.3.1”

propionate CoA-transferase activity definition “Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA.”
- database_cross_reference “RHEA:23520”

propionyl-CoA:succinate CoA-transferase activity definition “Catalysis of the reaction: succinate + propionyl-CoA = succinyl-CoA + propionate.”
- database_cross_reference “PMID:10769117”

propionyl-CoA:succinate CoA-transferase activity definition “Catalysis of the reaction: succinate + propionyl-CoA = succinyl-CoA + propionate.”
- database_cross_reference “RHEA:28010”
- database_cross_reference “PMID:10769117”

protein import into mitochondrial matrix term tracker item “/github.com/geneontology/go-ontology/issues/29962”^^anyURI
protein import into mitochondrial matrix definition “The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.”
- database_cross_reference “ISBN:0716731363”
protein import into mitochondrial matrix SubClassOf intercellular transport
protein import into mitochondrial matrix SubClassOf protein transmembrane transport
protein import into mitochondrial matrix SubClassOf establishment of protein localization to organelle

protein-macromolecule adaptor activity term tracker item “https://github.com/geneontology/go-ontology/issues/31444”^^anyURI
protein-macromolecule adaptor activity comment “Note that protein complex scaffolds should use GO:0140378 protein complex scaffold activity.”

AnnotationProperty: relatedMatch

ricinine nitrilase activity definition “Catalysis of the reaction: ricinine + 2 H2O = 4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate + NH4+.”
- database_cross_reference “RHEA:22704”

ricinine nitrilase activity definition “Catalysis of the reaction: ricinine + 2 H2O = 4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate + NH4+.”
- database_cross_reference “RHEA:22704”

succinate-hydroxymethylglutarate CoA-transferase activity definition “Catalysis of the reaction: (S)-3-hydroxy-3-methylglutarate + succinyl-CoA = 3-hydroxy-3-methyl-glutaryl-CoA + succinate.”
- database_cross_reference “MetaCyc:2.8.3.13-RXN”
- database_cross_reference “EC:2.8.3.13”

succinate-hydroxymethylglutarate CoA-transferase activity definition “Catalysis of the reaction: 3-hydroxy-3-methylglutarate + succinyl-CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + succinate.”
- database_cross_reference “RHEA:12284”

succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity definition “Catalysis of the reaction: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate.”
- database_cross_reference “RHEA:16469”
- database_cross_reference “EC:2.8.3.15”

succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity definition “Catalysis of the reaction: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate.”
- database_cross_reference “RHEA:16469”

succinyl-CoA:(R)-citramalate CoA-transferase activity definition “Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA.”
- database_cross_reference “GOC:jl”
- database_cross_reference “PMID:17259315”

succinyl-CoA:(R)-citramalate CoA-transferase activity definition “Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA.”
- database_cross_reference “PMID:17259315”
- database_cross_reference “RHEA:38279”

sugar-phosphatase activity definition “Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate.”
- database_cross_reference “MetaCyc:SUGAR-PHOSPHATASE-RXN”
- database_cross_reference “EC:3.1.3.23”

sugar-phosphatase activity definition “Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate.”
- database_cross_reference “EC:3.1.3.23”

sulfate adenylyltransferase (ATP) activity definition “Catalysis of the reaction: ATP + H+ + sulfate = adenosine 5’-phosphosulfate + diphosphate.”
- database_cross_reference “EC:2.7.7.4”

sulfate adenylyltransferase (ATP) activity definition “Catalysis of the reaction: sulfate + ATP + H+ = adenosine 5’-phosphosulfate + diphosphate.”
- database_cross_reference “RHEA:18133”

sulfopropanediol 3-dehydrogenase activity database_cross_reference “MetaCyc:RXN-11729”
sulfopropanediol 3-dehydrogenase activity definition “Catalysis of the reaction: (2R)-3-sulfopropanediol(1-) + NAD = 2-oxo-3-hydroxy-propane-1-sulfonate + NADH + H+.”
- database_cross_reference “GOC:pz”
- database_cross_reference “PMID:20150239”
sulfopropanediol 3-dehydrogenase activity label “(R)-sulfopropanediol 2-dehydrogenase activity”

Class: symbiont-mediated disassembly of host stress granules
symbiont-mediated disassembly of host stress granules term tracker item “https://github.com/geneontology/go-ontology/issues/31751”^^anyURI
symbiont-mediated disassembly of host stress granules created by “pg”
symbiont-mediated disassembly of host stress granules creation date “2026-04-07T12:22:21Z”
symbiont-mediated disassembly of host stress granules has_obo_namespace “biological_process”
symbiont-mediated disassembly of host stress granules id “GO:0140402”
symbiont-mediated disassembly of host stress granules definition “The process in which an organism effects a change that impairs the structure or function of the stress granule of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. Stress granules are dynamic cytoplasmic condensates formed through liquid-liquid phase separation. They act as a critical hub for both cellular stress adaptation and defense against viruses.”
- database_cross_reference “PMID:32353859”
- database_cross_reference “PMID:39345463”
symbiont-mediated disassembly of host stress granules label “symbiont-mediated disassembly of host stress granules”
symbiont-mediated disassembly of host stress granules SubClassOf symbiont-mediated disruption of host cellular anatomical structure

tRNA wobble position uridine thiolation definition “The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.”
- database_cross_reference “PMID:16871210”

tRNA wobble position uridine thiolation definition “The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from L-cysteine to position C2 by several steps.”
- database_cross_reference “PMID:16871210”

terephthalate 1,2-dioxygenase activity definition “Catalysis of the reaction: H+ + NADH + O2 + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+.”
- database_cross_reference “EC:1.14.12.15”
- database_cross_reference “RHEA:10312”

terephthalate 1,2-dioxygenase activity definition “Catalysis of the reaction: terephthalate + NADH + O2 + H+ = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+.”
- database_cross_reference “RHEA:10312”

toluene dioxygenase activity definition “Catalysis of the reaction: H+ + NADH + O2 + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD+.”
- database_cross_reference “EC:1.14.12.11”
- database_cross_reference “RHEA:16737”

toluene dioxygenase activity definition “Catalysis of the reaction: toluene + NADH + O2 + H+ = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD+.”
- database_cross_reference “RHEA:16737”

Class: vesicle docking activity
vesicle docking activity term tracker item “https://github.com/geneontology/go-ontology/issues/31880”^^anyURI
vesicle docking activity created by “rynl”
vesicle docking activity creation date “2026-04-17T21:35:33Z”
vesicle docking activity has_obo_namespace “molecular_function”
vesicle docking activity id “GO:0160321”
vesicle docking activity definition “The binding activity of a protein that directly mediates the stable attachment of a transport vesicle to a target membrane, bringing the two membranes into close apposition.”
- database_cross_reference “PMID:28237810”
vesicle docking activity comment “Vesicle docking activity succeeds vesicle tethering activity and precedes fusogenic activity in the vesicle membrane fusion pathway.”
vesicle docking activity label “vesicle docking activity”
vesicle docking activity SubClassOf membrane-membrane adaptor activity

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go-ontology

Ontology comparison

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Ontology imports

Ontology annotations

Removed

Added

‘de novo’ NAD+ biosynthetic process from L-tryptophan http://purl.obolibrary.org/obo/GO_0034354

Added

(2E)-enoyl-CoA hydratase activity http://purl.obolibrary.org/obo/GO_0080023

Added

(3R)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity http://purl.obolibrary.org/obo/GO_0106386

Added

(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity http://purl.obolibrary.org/obo/GO_0003857

Added

(R)-2-hydroxy-4-methylpentanoate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0043712

Removed

Added

1,2-dihydroxynaphthalene dioxygenase activity http://purl.obolibrary.org/obo/GO_0018554

Removed

Added

1,8-cineole synthase activity http://purl.obolibrary.org/obo/GO_0102313

Removed

Added

1-acylglycerol-3-phosphate O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0003841

Added

1-acylglycerophosphocholine O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047184

Removed

Added

1-acylglycerophosphoethanolamine O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0106262

Removed

Added

1-acylglycerophosphoserine O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0106263

Removed

Added

1-alkenylglycerophosphoethanolamine O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047166

Removed

Added

1-alkyl-2-acetylglycerol O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047167

Removed

Added

1-alkylglycerophosphocholine O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047191

Removed

Added

2,4-dienoyl-CoA reductase (NADPH) activity http://purl.obolibrary.org/obo/GO_0008670

Added

2,5-dioxovalerate dehydrogenase (NAD+) activity http://purl.obolibrary.org/obo/GO_0044104

Removed

Added

2,5-dioxovalerate dehydrogenase (NADP+) activity http://purl.obolibrary.org/obo/GO_0047533

Removed

Added

2-(omega-methylthio)alkylmalate dehydratase activity http://purl.obolibrary.org/obo/GO_0120528

Added

2-acylglycerol O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0003846

Added

2-acylglycerol-3-phosphate O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047144

Removed

2-acylglycerophosphocholine O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047190

Removed

Added

2-aminobenzenesulfonate 2,3-dioxygenase activity http://purl.obolibrary.org/obo/GO_0018627

Removed

Added

2-aminobenzenesulfonate catabolic process http://purl.obolibrary.org/obo/GO_0046230

Removed

2-hydroxyacyl-CoA lyase activity http://purl.obolibrary.org/obo/GO_0106359

Added

2-hydroxyquinoline 5,6-dioxygenase activity http://purl.obolibrary.org/obo/GO_0018629

Removed

Added

2-keto-3-deoxygluconate:proton symporter activity http://purl.obolibrary.org/obo/GO_0015649

Added

3’-phosphoadenosine 5’-phosphosulfate transport http://purl.obolibrary.org/obo/GO_0046963

Removed

3-alpha-hydroxysteroid 3-dehydrogenase [NAD(P)+] activity http://purl.obolibrary.org/obo/GO_0140169

Added

3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity http://purl.obolibrary.org/obo/GO_0003854

Added

‘de novo’ NAD+ biosynthetic process from L-tryptophan `http://purl.obolibrary.org/obo/GO_0034354`

(2E)-enoyl-CoA hydratase activity `http://purl.obolibrary.org/obo/GO_0080023`

(3R)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity `http://purl.obolibrary.org/obo/GO_0106386`

(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity `http://purl.obolibrary.org/obo/GO_0003857`

(R)-2-hydroxy-4-methylpentanoate CoA-transferase activity `http://purl.obolibrary.org/obo/GO_0043712`

1,2-dihydroxynaphthalene dioxygenase activity `http://purl.obolibrary.org/obo/GO_0018554`

1,8-cineole synthase activity `http://purl.obolibrary.org/obo/GO_0102313`

1-acylglycerol-3-phosphate O-acyltransferase activity `http://purl.obolibrary.org/obo/GO_0003841`

1-acylglycerophosphocholine O-acyltransferase activity `http://purl.obolibrary.org/obo/GO_0047184`

1-acylglycerophosphoethanolamine O-acyltransferase activity `http://purl.obolibrary.org/obo/GO_0106262`

1-acylglycerophosphoserine O-acyltransferase activity `http://purl.obolibrary.org/obo/GO_0106263`

1-alkenylglycerophosphoethanolamine O-acyltransferase activity `http://purl.obolibrary.org/obo/GO_0047166`

1-alkyl-2-acetylglycerol O-acyltransferase activity `http://purl.obolibrary.org/obo/GO_0047167`

1-alkylglycerophosphocholine O-acyltransferase activity `http://purl.obolibrary.org/obo/GO_0047191`

2,4-dienoyl-CoA reductase (NADPH) activity `http://purl.obolibrary.org/obo/GO_0008670`

2,5-dioxovalerate dehydrogenase (NAD+) activity `http://purl.obolibrary.org/obo/GO_0044104`

2,5-dioxovalerate dehydrogenase (NADP+) activity `http://purl.obolibrary.org/obo/GO_0047533`

2-(omega-methylthio)alkylmalate dehydratase activity `http://purl.obolibrary.org/obo/GO_0120528`

2-acylglycerol O-acyltransferase activity `http://purl.obolibrary.org/obo/GO_0003846`

2-acylglycerol-3-phosphate O-acyltransferase activity `http://purl.obolibrary.org/obo/GO_0047144`

2-acylglycerophosphocholine O-acyltransferase activity `http://purl.obolibrary.org/obo/GO_0047190`

2-aminobenzenesulfonate 2,3-dioxygenase activity `http://purl.obolibrary.org/obo/GO_0018627`

2-aminobenzenesulfonate catabolic process `http://purl.obolibrary.org/obo/GO_0046230`

2-hydroxyacyl-CoA lyase activity `http://purl.obolibrary.org/obo/GO_0106359`

2-hydroxyquinoline 5,6-dioxygenase activity `http://purl.obolibrary.org/obo/GO_0018629`

2-keto-3-deoxygluconate:proton symporter activity `http://purl.obolibrary.org/obo/GO_0015649`

3’-phosphoadenosine 5’-phosphosulfate transport `http://purl.obolibrary.org/obo/GO_0046963`

3-alpha-hydroxysteroid 3-dehydrogenase [NAD(P)+] activity `http://purl.obolibrary.org/obo/GO_0140169`

3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity `http://purl.obolibrary.org/obo/GO_0003854`

3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity `http://purl.obolibrary.org/obo/GO_0102175`

3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity `http://purl.obolibrary.org/obo/GO_0000252`

3-butenylglucosinolate 2-hydroxylase activity `http://purl.obolibrary.org/obo/GO_0062131`

3-chlorobenzoate-3,4-oxygenase activity `http://purl.obolibrary.org/obo/GO_0102045`

3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity `http://purl.obolibrary.org/obo/GO_0017060`

3-hydroxy-2-methylpyridinecarboxylate dioxygenase [NAD(P)H] activity `http://purl.obolibrary.org/obo/GO_0047081`

3-hydroxyacyl-CoA dehydratase activity `http://purl.obolibrary.org/obo/GO_0018812`

3-oxoadipate CoA-transferase activity `http://purl.obolibrary.org/obo/GO_0047569`

3-phenylpropionate dioxygenase activity `http://purl.obolibrary.org/obo/GO_0008695`

3-sulfino-L-alanine: proton, glutamate antiporter activity `http://purl.obolibrary.org/obo/GO_0000514`

4-(trimethylammonio)butanoate transport `http://purl.obolibrary.org/obo/GO_1900751`

4-O-methyl-glucuronoyl methylesterase activity `http://purl.obolibrary.org/obo/GO_0052797`

4-aminobenzoate biosynthetic process `http://purl.obolibrary.org/obo/GO_0008153`

4-chlorophenylacetate 3,4-dioxygenase activity `http://purl.obolibrary.org/obo/GO_0018622`

4-hydroxy-L-isoleucine dehydrogenase activity `http://purl.obolibrary.org/obo/GO_0102394`

4-hydroxybutanoyl-CoA dehydratase activity `http://purl.obolibrary.org/obo/GO_0043721`

4-phosphoerythronate phosphatase activity `http://purl.obolibrary.org/obo/GO_0140401`

4-sulfobenzoate 3,4-dioxygenase activity `http://purl.obolibrary.org/obo/GO_0018621`

5’-(N(7)-methyl 5’-triphosphoguanosine)-[mRNA] diphosphatase activity `http://purl.obolibrary.org/obo/GO_0140932`

5’-(N(7)-methylguanosine 5’-triphospho)-[mRNA] hydrolase activity `http://purl.obolibrary.org/obo/GO_0140933`

5’-adenylyl sulfate transmembrane transport `http://purl.obolibrary.org/obo/GO_1902558`

5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity `http://purl.obolibrary.org/obo/GO_0097265`

5,6,7,8-tetrahydromethanopterin catabolic process `http://purl.obolibrary.org/obo/GO_1901284`

5,6,7,8-tetrahydrosarcinapterin catabolic process `http://purl.obolibrary.org/obo/GO_1901854`

5-aminolevulinic acid import across plasma membrane `http://purl.obolibrary.org/obo/GO_0140484`

5-formyltetrahydrofolate transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0015231`

5-hydroxypentanoate CoA-transferase activity `http://purl.obolibrary.org/obo/GO_0047591`

5-phosphoribose 1-diphosphate biosynthetic process `http://purl.obolibrary.org/obo/GO_0006015`