--- go-lastrelease.obo 2025-12-30 05:37:33.346952046 +0000
+++ go.obo 2025-12-30 05:47:26.037728094 +0000
@@ -1,5 +1,5 @@
format-version: 1.2
-data-version: releases/2025-10-10
+data-version: releases/2025-12-30
subsetdef: chebi_ph7_3 "Rhea list of ChEBI terms representing the major species at pH 7.3."
subsetdef: gocheck_do_not_annotate "Term not to be used for direct annotation"
subsetdef: gocheck_obsoletion_candidate "Terms planned for obsoletion"
@@ -26,15 +26,25 @@
synonymtypedef: systematic_synonym "Systematic synonym" EXACT
default-namespace: gene_ontology
idspace: dc http://purl.org/dc/elements/1.1/
+idspace: EC http://purl.uniprot.org/enzyme/
+idspace: KEGG_REACTION http://www.kegg.jp/entry/
+idspace: MetaCyc http://identifiers.org/metacyc.reaction/
idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl#
+idspace: Reactome http://identifiers.org/reactome/
+idspace: RHEA http://rdf.rhea-db.org/
+idspace: skos http://www.w3.org/2004/02/skos/core#
+idspace: TC http://identifiers.org/tcdb/
idspace: terms http://purl.org/dc/terms/
+idspace: UM-BBD_pathwayID http://identifiers.org/umbbd.pathway/
+idspace: UM-BBD_reactionID http://identifiers.org/umbbd.reaction/
+idspace: VZ https://viralzone.expasy.org/
ontology: go
property_value: dc:description "The Gene Ontology (GO) provides a framework and set of concepts for describing the functions of gene products from all organisms." xsd:string
property_value: dc:title "Gene Ontology" xsd:string
property_value: has_ontology_root_term GO:0003674
property_value: has_ontology_root_term GO:0005575
property_value: has_ontology_root_term GO:0008150
-property_value: owl:versionInfo "2025-10-10" xsd:string
+property_value: owl:versionInfo "2025-12-30" xsd:string
property_value: terms:license http://creativecommons.org/licenses/by/4.0/
[Term]
@@ -59,8 +69,6 @@
id: GO:0000003
name: obsolete reproduction
namespace: biological_process
-alt_id: GO:0019952
-alt_id: GO:0050876
def: "OBSOLETE. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms." [GOC:go_curators, GOC:isa_complete, GOC:jl, ISBN:0198506732]
comment: The reason for obsoletion is that this term is equivalent to reproductive process.
synonym: "reproductive physiological process" EXACT []
@@ -133,9 +141,12 @@
xref: MetaCyc:TRANS-HEXAPRENYLTRANSTRANSFERASE-RXN
xref: RHEA:27794
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.30
+property_value: skos:exactMatch RHEA:27794
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23472" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27609" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-09-16T11:50:41Z
@@ -187,6 +198,9 @@
xref: Reactome:R-HSA-5658001 "Defective LCT does not hydrolyze Lac"
xref: RHEA:10076
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.108
+property_value: skos:exactMatch RHEA:10076
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000017
@@ -334,7 +348,11 @@
name: mannosylphosphate transferase activity
namespace: molecular_function
def: "Catalysis of the reaction: GDP-alpha-D-mannose + n {[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]-alpha-D-Man-(1->6)}60-(Man9GlcNAc2-[protein] = phosphorylated {[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]-alpha-D-Man-(1->6)}60-(Man9GlcNAc2-[protein] + n GMP + n H+ or GDP-alpha-D-mannose + alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-3-O-(Ser/Thr)-[protein] = alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-[alpha-D-Man-6P-]-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-3-O-(Ser/Thr)-[protein] + GMP + H+." [MetaCyc:RXN-22693, MetaCyc:RXN-22694]
+xref: MetaCyc:RXN-22693
+xref: MetaCyc:RXN-22694
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:narrowMatch MetaCyc:RXN-22693
+property_value: skos:narrowMatch MetaCyc:RXN-22694
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28340" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28811" xsd:anyURI
@@ -374,6 +392,8 @@
xref: RHEA:23688
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.2
+property_value: skos:exactMatch RHEA:23688
[Term]
id: GO:0000035
@@ -477,8 +497,10 @@
is_a: GO:0016755 ! aminoacyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.3.2.12
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22192" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000049
@@ -487,7 +509,6 @@
alt_id: GO:0000946
def: "Binding to a transfer RNA." [GOC:ai]
synonym: "base pairing with tRNA" NARROW []
-xref: Reactome:R-HSA-2408509 "Sec-tRNA(Sec) binds to EEFSEC:GTP"
is_a: GO:0003723 ! RNA binding
[Term]
@@ -502,8 +523,8 @@
synonym: "urea biosynthetic process" EXACT []
xref: Reactome:R-HSA-70635 "Urea cycle"
xref: Wikipedia:Urea_cycle
+is_a: GO:0009058 ! biosynthetic process
is_a: GO:0019627 ! urea metabolic process
-is_a: GO:0043604 ! amide biosynthetic process
[Term]
id: GO:0000051
@@ -1054,7 +1075,9 @@
xref: KEGG_REACTION:R00412
xref: RHEA:16357
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch RHEA:16357
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17091" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000105
@@ -1084,6 +1107,8 @@
xref: MetaCyc:GLUTAMIDOTRANS-RXN
xref: RHEA:24793
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch RHEA:24793
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000108
@@ -1231,6 +1256,10 @@
xref: MetaCyc:RXN-14964
xref: RHEA:46084
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.21
+property_value: skos:broadMatch MetaCyc:GLYCEROL-1-PHOSPHATASE-RXN
+property_value: skos:exactMatch MetaCyc:RXN-14964
+property_value: skos:exactMatch RHEA:46084
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27964" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
@@ -1418,9 +1447,16 @@
synonym: "palmitoyldihydroxyacetone-phosphate reductase activity" RELATED [EC:1.1.1.101]
xref: EC:1.1.1.101
xref: MetaCyc:ACYLGLYCERONE-PHOSPHATE-REDUCTASE-RXN
+xref: MetaCyc:RXN-15046
xref: Reactome:R-HSA-75883 "DHRS7B reduces GO3P to HXDG3P"
xref: RHEA:17341
+xref: RHEA:36175
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.101
+property_value: skos:exactMatch MetaCyc:ACYLGLYCERONE-PHOSPHATE-REDUCTASE-RXN
+property_value: skos:exactMatch RHEA:17341
+property_value: skos:narrowMatch MetaCyc:RXN-15046
+property_value: skos:narrowMatch RHEA:36175
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -1476,8 +1512,11 @@
is_a: GO:0003774 ! cytoskeletal motor activity
is_a: GO:0120544 ! polypeptide conformation or assembly isomerase activity
is_a: GO:0140657 ! ATP-dependent activity
+property_value: skos:exactMatch EC:5.6.1.8
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20877" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29690" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0000147
@@ -1593,6 +1632,7 @@
is_a: GO:0004673 ! protein histidine kinase activity
is_a: GO:0140299 ! molecular sensor activity
relationship: part_of GO:0000160 ! phosphorelay signal transduction system
+property_value: skos:broadMatch EC:2.7.13.3
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28061" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -1731,6 +1771,7 @@
namespace: molecular_function
def: "OBSOLETE. Catalysis of the hydroxylation of sphingolipid long chain bases." [PMID:9556590]
comment: The reason for obsoletion is that this term is equivalent to sphingolipid C4-monooxygenase activity.
+xref: Reactome:R-HSA-428260 "DEGS2 oxygenates dihydroceramide"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29717" xsd:anyURI
is_obsolete: true
replaced_by: GO:0102772
@@ -1776,14 +1817,12 @@
synonym: "3'-5'-exoribonuclease activity" EXACT []
xref: Reactome:R-HSA-430028 "Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion"
xref: Reactome:R-HSA-6791222 "21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA"
+xref: Reactome:R-HSA-6791227 "47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA"
xref: Reactome:R-HSA-9682603 "nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA"
xref: Reactome:R-HSA-9694632 "nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA"
xref: Reactome:R-HSA-9822437 "DIS3L2 hydrolyzes uridylated mRNA"
xref: Reactome:R-HSA-9836585 "SUPV3L1:PNPT1 hydrolyzes mitochondrial RNA to yield 4-5 nucleotide oligoribonucleotides"
xref: Reactome:R-HSA-9836822 "REXO2 hydrolyzes 4-5 nucleotide RNAs to ribonucleotides"
-xref: Reactome:R-HSA-9933585 "RNA exosome in PAXT:PAPOLG:TENT4A,B:ZC3H3:CBCA:polyadenylated m7GpppN-RNA:PABPN1 hydrolyzes RNA"
-xref: Reactome:R-HSA-9934763 "The RNA exosome in RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA hydrolyzes RNA"
-xref: Reactome:R-HSA-9935824 "TRAMP:RNA exosome hydrolyzes oligoadenylated pre-rRNA 5' external transcribed spacer (5'ETS)"
is_a: GO:0008408 ! 3'-5' exonuclease activity
is_a: GO:0016896 ! RNA exonuclease activity, producing 5'-phosphomonoesters
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28062" xsd:anyURI
@@ -2210,7 +2249,10 @@
xref: MetaCyc:NADPYROPHOSPHAT-RXN
xref: RHEA:11800
is_a: GO:0004551 ! dinucleotide phosphatase activity
+property_value: skos:broadMatch EC:3.6.1.22
+property_value: skos:exactMatch RHEA:11800
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19775" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000211
@@ -2251,7 +2293,9 @@
is_a: GO:0004521 ! RNA endonuclease activity
is_a: GO:0004549 ! tRNA-specific ribonuclease activity
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
+property_value: skos:exactMatch EC:4.6.1.16
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000214
@@ -2281,6 +2325,9 @@
xref: RHEA:23324
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.7.1.160
+property_value: skos:exactMatch RHEA:23324
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000216
@@ -2376,6 +2423,8 @@
xref: MetaCyc:3.5.1.52-RXN
xref: Reactome:R-HSA-8850594 "Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins"
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.52
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000225
@@ -2394,6 +2443,9 @@
xref: RHEA:11660
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0019213 ! deacetylase activity
+property_value: skos:exactMatch EC:3.5.1.89
+property_value: skos:exactMatch RHEA:11660
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000226
@@ -2493,8 +2545,21 @@
xref: EC:2.1.1.103
xref: KEGG_REACTION:R02037
xref: KEGG_REACTION:R06868
+xref: MetaCyc:2.1.1.103-RXN
+xref: MetaCyc:RXN-5642
+xref: MetaCyc:RXN-5643
+xref: RHEA:20365
+xref: RHEA:25321
+xref: RHEA:25325
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.103
+property_value: skos:narrowMatch MetaCyc:2.1.1.103-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-5642
+property_value: skos:narrowMatch MetaCyc:RXN-5643
+property_value: skos:narrowMatch RHEA:20365
+property_value: skos:narrowMatch RHEA:25321
+property_value: skos:narrowMatch RHEA:25325
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -2643,6 +2708,9 @@
xref: MetaCyc:1.3.1.71-RXN
xref: RHEA:18501
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.71
+property_value: skos:exactMatch RHEA:18501
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000247
@@ -2653,6 +2721,8 @@
xref: MetaCyc:RXN3O-203
xref: RHEA:33435
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch MetaCyc:RXN3O-203
+property_value: skos:exactMatch RHEA:33435
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
[Term]
@@ -2673,7 +2743,13 @@
def: "Catalysis of the reaction: 5-dehydroepisterol + H+ + NADPH + O2 = ergosta-5,7,22,24(28)-tetraen-3beta-ol + 2 H2O + NADP+. This reaction is the introduction of a double bond between the C-22 and C-23 carbons of certain sterols. Also converts sitosterol and 24-epi-campesterol to stigmasterol and brassicasterol, respectively." [EC:1.14.19.41]
xref: EC:1.14.19.41
xref: MetaCyc:RXN3O-227
+xref: RHEA:33467
+xref: RHEA:46576
is_a: GO:0070704 ! sterol desaturase activity
+property_value: skos:exactMatch EC:1.14.19.41
+property_value: skos:exactMatch MetaCyc:RXN3O-227
+property_value: skos:narrowMatch RHEA:33467
+property_value: skos:narrowMatch RHEA:46576
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27381" xsd:anyURI
[Term]
@@ -2701,6 +2777,9 @@
xref: Reactome:R-HSA-191366 "Squalene 2,3-epoxide cyclizes, forming lanosterol"
xref: RHEA:14621
is_a: GO:0031559 ! oxidosqualene cyclase activity
+property_value: skos:exactMatch EC:5.4.99.7
+property_value: skos:exactMatch RHEA:14621
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000252
@@ -2720,9 +2799,10 @@
xref: EC:1.1.1.170
xref: Reactome:R-HSA-194642 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one"
xref: Reactome:R-HSA-194718 "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)"
-xref: Reactome:R-HSA-9945787 "NSDHL decarboxylates 4a-carboxy-5a-cholest-8-ene-3b-ol to 5a-cholest-8-en-3-one"
-xref: Reactome:R-HSA-9945822 "NSDHL decarboxylates 4a-carboxy-4b-methyl-5a-cholest-8-en-3b-ol to 4a-methyl-5a-cholest-8-en-3b-ol"
+xref: RHEA:34771
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.170
+property_value: skos:narrowMatch RHEA:34771
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20597" xsd:anyURI
[Term]
@@ -2739,11 +2819,16 @@
xref: MetaCyc:RXN-13686
xref: Reactome:R-HSA-194632 "Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol)"
xref: Reactome:R-HSA-194689 "4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol"
-xref: Reactome:R-HSA-9945784 "HSD17B7 reduces 4a-methyl-5a-cholest-8-en-3-one to 4a-methyl-5a-cholest-8-en-3b-ol"
-xref: Reactome:R-HSA-9945804 "HSD17B7 reduces 5a-cholest-8-en-3-one to ZYMSTNL"
+xref: RHEA:18409
xref: RHEA:34787
+xref: RHEA:36379
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.270
+property_value: skos:exactMatch RHEA:34787
+property_value: skos:narrowMatch RHEA:18409
+property_value: skos:narrowMatch RHEA:36379
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29311" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000254
@@ -2757,12 +2842,13 @@
xref: MetaCyc:RXN-13188
xref: Reactome:R-HSA-194641 "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol"
xref: Reactome:R-HSA-194669 "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol"
-xref: Reactome:R-HSA-9947203 "MSMO1 oxidizes 4,4-diMe-5-cholest-8-en-3-ol to 4a-carboxy-4b-me-5a-cholest-8-en-3b-ol"
-xref: Reactome:R-HSA-9947207 "MSMO1 oxidizes 4a-me-5a-cholest-8-en-3b-ol to 4a-carboxy-5a-cholest-8-ene-3b-ol"
xref: RHEA:55220
is_a: GO:0016716 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.18.9
+property_value: skos:exactMatch RHEA:55220
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23278" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25815" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000255
@@ -2770,7 +2856,7 @@
namespace: biological_process
def: "The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism." [GOC:mah, ISBN:0198547684]
synonym: "allantoin metabolism" EXACT []
-is_a: GO:0043603 ! amide metabolic process
+is_a: GO:0008152 ! metabolic process
[Term]
id: GO:0000256
@@ -2781,7 +2867,7 @@
synonym: "allantoin catabolism" EXACT []
synonym: "allantoin degradation" EXACT []
is_a: GO:0000255 ! allantoin metabolic process
-is_a: GO:0043605 ! amide catabolic process
+is_a: GO:0009056 ! catabolic process
[Term]
id: GO:0000257
@@ -2798,6 +2884,8 @@
xref: UM-BBD_reactionID:r0377
xref: UM-BBD_reactionID:r0701
is_a: GO:0016815 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles
+property_value: skos:exactMatch EC:3.5.5.1
+property_value: skos:exactMatch RHEA:21724
[Term]
id: GO:0000258
@@ -3018,6 +3106,9 @@
xref: MetaCyc:2.1.1.59-RXN
xref: RHEA:24312
is_a: GO:0016279 ! protein-lysine N-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.59
+property_value: skos:exactMatch RHEA:24312
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000278
@@ -3110,7 +3201,10 @@
xref: Reactome:R-HSA-1676168 "PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane"
xref: RHEA:13609
is_a: GO:0052742 ! phosphatidylinositol kinase activity
+property_value: skos:exactMatch EC:2.7.1.150
+property_value: skos:exactMatch RHEA:13609
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28336" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000286
@@ -3129,6 +3223,9 @@
xref: MetaCyc:ALANINE-DEHYDROGENASE-RXN
xref: RHEA:18405
is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors
+property_value: skos:exactMatch EC:1.4.1.1
+property_value: skos:exactMatch RHEA:18405
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000287
@@ -3266,6 +3363,9 @@
xref: MetaCyc:ENDOPOLYPHOSPHATASE-RXN
xref: RHEA:22452
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.10
+property_value: skos:exactMatch RHEA:22452
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000299
@@ -3382,6 +3482,9 @@
xref: Reactome:R-HSA-8939959 "NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+"
xref: RHEA:21360
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.1
+property_value: skos:exactMatch MetaCyc:2.7.7.1-RXN
+property_value: skos:exactMatch RHEA:21360
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29467" xsd:anyURI
[Term]
@@ -3402,6 +3505,8 @@
xref: MetaCyc:XANPRIBOSYLTRAN-RXN
xref: RHEA:10800
is_a: GO:0106130 ! purine phosphoribosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.22
+property_value: skos:exactMatch RHEA:10800
[Term]
id: GO:0000311
@@ -3615,6 +3720,9 @@
xref: RHEA:17953
xref: UM-BBD_reactionID:r1027
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.6
+property_value: skos:exactMatch RHEA:17953
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000335
@@ -4005,7 +4113,6 @@
namespace: molecular_function
def: "Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon." [GOC:krc, ISBN:0879695897, PMID:19239890]
synonym: "lariat formation, 5'-splice site cleavage" RELATED []
-xref: Reactome:R-HSA-9794542 "Formation of the Spliceosomal C complex containing intron lariat"
is_a: GO:0140098 ! catalytic activity, acting on RNA
relationship: part_of GO:0000375 ! RNA splicing, via transesterification reactions
@@ -5113,7 +5220,9 @@
is_a: GO:0015179 ! L-amino acid transmembrane transporter activity
is_a: GO:0072349 ! modified amino acid transmembrane transporter activity
is_a: GO:0140848 ! amino acid:monoatomic cation antiporter activity
+property_value: skos:exactMatch RHEA:70967
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23042" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-03-21T17:18:20Z
@@ -5126,7 +5235,9 @@
xref: RHEA:70783
is_a: GO:0015183 ! L-aspartate transmembrane transporter activity
is_a: GO:0106421 ! L-glutamate:proton antiporter activity
+property_value: skos:exactMatch RHEA:70783
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23041" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-03-21T17:33:23Z
@@ -5154,6 +5265,8 @@
synonym: "A/G-specific adenine DNA glycosylase activity" NARROW []
xref: EC:3.2.2.31
is_a: GO:0000700 ! mismatch base pair DNA N-glycosylase activity
+property_value: skos:exactMatch EC:3.2.2.31
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000702
@@ -5361,6 +5474,9 @@
xref: MetaCyc:RR-BUTANEDIOL-DEHYDROGENASE-RXN
xref: RHEA:24340
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.4
+property_value: skos:exactMatch RHEA:24340
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000722
@@ -5591,15 +5707,16 @@
[Term]
id: GO:0000745
-name: nuclear migration involved in conjugation with mutual genetic exchange
+name: obsolete nuclear migration involved in conjugation with mutual genetic exchange
namespace: biological_process
-def: "The net movement of nuclei towards one another, leading to the bilateral transfer of genetic material in organisms undergoing conjugation without cellular fusion." [GOC:clt, GOC:mah]
+def: "OBSOLETE. The net movement of nuclei towards one another, leading to the bilateral transfer of genetic material in organisms undergoing conjugation without cellular fusion." [GOC:clt, GOC:mah]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "nuclear exchange during conjugation without cellular fusion" RELATED []
synonym: "nuclear migration involved in conjugation without cellular fusion" EXACT [GOC:dph, GOC:tb]
-is_a: GO:0007097 ! nuclear migration
-intersection_of: GO:0007097 ! nuclear migration
-intersection_of: part_of GO:0000748 ! conjugation with mutual genetic exchange
-relationship: part_of GO:0000744 ! karyogamy involved in conjugation with mutual genetic exchange
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0000748
+consider: GO:0007097
[Term]
id: GO:0000746
@@ -5823,14 +5940,15 @@
[Term]
id: GO:0000766
-name: negative adaptation of signaling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation
+name: obsolete negative adaptation of signaling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation
namespace: biological_process
-def: "In organisms that undergo pheromone-induced unidirectional conjugation, the process involved in desensitization following exposure to pheromone stimulus that acts to down-regulate further stimulation or block initial conjugation responses." [GOC:clt]
+def: "OBSOLETE. In organisms that undergo pheromone-induced unidirectional conjugation, the process involved in desensitization following exposure to pheromone stimulus that acts to down-regulate further stimulation or block initial conjugation responses." [GOC:clt]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "adaptation to pheromone during pheromone-induced unidirectional conjugation" RELATED [GOC:dph, GOC:tb]
synonym: "desensitization to pheromone during pheromone-induced unidirectional conjugation" EXACT []
synonym: "negative adaptation of signalling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation" EXACT [GOC:mah]
-is_a: GO:0022401 ! negative adaptation of signaling pathway
-relationship: part_of GO:0000765 ! response to pheromone regulating pheromone-induced unidirectional conjugation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0000767
@@ -5870,7 +5988,7 @@
alt_id: GO:0007325
def: "The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones." [GOC:elh]
synonym: "a-factor export" NARROW []
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23245" xsd:anyURI
[Term]
@@ -5903,9 +6021,21 @@
synonym: "PLMT" EXACT []
synonym: "S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase activity" RELATED [EC:2.1.1.71]
xref: EC:2.1.1.71
+xref: KEGG_REACTION:R01320
+xref: KEGG_REACTION:R03424
xref: MetaCyc:2.1.1.71-RXN
+xref: MetaCyc:RXN4FS-2
+xref: RHEA:32735
+xref: RHEA:32739
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.71
+property_value: skos:exactMatch MetaCyc:2.1.1.71-RXN
+property_value: skos:narrowMatch KEGG_REACTION:R01320
+property_value: skos:narrowMatch KEGG_REACTION:R03424
+property_value: skos:narrowMatch MetaCyc:RXN4FS-2
+property_value: skos:narrowMatch RHEA:32735
+property_value: skos:narrowMatch RHEA:32739
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -6220,7 +6350,10 @@
xref: MetaCyc:RXN-11277
xref: RHEA:27449
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.75
+property_value: skos:exactMatch RHEA:27449
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24052" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000811
@@ -6333,6 +6466,10 @@
xref: MetaCyc:2.7.1.151-RXN
xref: RHEA:17717
is_a: GO:0051766 ! inositol trisphosphate kinase activity
+property_value: skos:broadMatch EC:2.7.1.151
+property_value: skos:exactMatch KEGG_REACTION:R05800
+property_value: skos:exactMatch MetaCyc:2.7.1.151-RXN
+property_value: skos:exactMatch RHEA:17717
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
@@ -6351,6 +6488,10 @@
xref: Reactome:R-HSA-1855185 "I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus"
xref: RHEA:11856
is_a: GO:0051765 ! inositol tetrakisphosphate kinase activity
+property_value: skos:broadMatch EC:2.7.1.151
+property_value: skos:exactMatch KEGG_REACTION:R05801
+property_value: skos:exactMatch MetaCyc:RXN-7162
+property_value: skos:exactMatch RHEA:11856
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
[Term]
@@ -6365,6 +6506,9 @@
xref: MetaCyc:RXN-7184
xref: Reactome:R-HSA-1855206 "I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus"
is_a: GO:0051765 ! inositol tetrakisphosphate kinase activity
+property_value: skos:broadMatch EC:2.7.1.151
+property_value: skos:exactMatch KEGG_REACTION:R10953
+property_value: skos:exactMatch MetaCyc:RXN-7184
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
[Term]
@@ -6440,6 +6584,10 @@
xref: MetaCyc:2.7.1.152-RXN
xref: RHEA:12793
is_a: GO:0000828 ! inositol hexakisphosphate kinase activity
+property_value: skos:broadMatch EC:2.7.4.21
+property_value: skos:exactMatch KEGG_REACTION:R09087
+property_value: skos:exactMatch MetaCyc:2.7.1.152-RXN
+property_value: skos:exactMatch RHEA:12793
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
[Term]
@@ -6586,6 +6734,9 @@
xref: MetaCyc:LUMAZINESYN-RXN
xref: RHEA:26152
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.78
+property_value: skos:exactMatch RHEA:26152
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000907
@@ -6609,6 +6760,9 @@
xref: MetaCyc:RXN0-299
xref: RHEA:15909
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.17
+property_value: skos:exactMatch RHEA:15909
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0000909
@@ -7296,7 +7450,6 @@
synonym: "RNA polymerase II promoter proximal region sequence-specific DNA binding" RELATED []
synonym: "RNA polymerase II proximal promoter sequence-specific DNA binding" RELATED []
synonym: "RNA polymerase II upstream activating sequence (UAS) sequence-specific DNA binding" RELATED []
-xref: Reactome:R-HSA-400204 "PPARA binds RXRA"
is_a: GO:0000977 ! RNA polymerase II transcription regulatory region sequence-specific DNA binding
is_a: GO:0000987 ! cis-regulatory region sequence-specific DNA binding
created_by: krc
@@ -7863,6 +8016,8 @@
def: "OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [GOC:txnOH]
comment: The reason for obsoletion is that this term is equivalent to DNA-directed 5'-3' RNA polymerase activity.
synonym: "DNA-directed RNA polymerase activity involved in transcription from RNA polymerase II promoter" EXACT []
+xref: Reactome:R-HSA-6814549 "Pre-snRNA transcript initiation, Integrator binding, LEC binding"
+xref: Reactome:R-HSA-6814559 "Pre-snRNA is elongated and capped with 7-methylguanosine"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23779" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
is_obsolete: true
@@ -7877,6 +8032,7 @@
def: "OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase III specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [GOC:txnOH]
comment: The reason for obsoletion is that this term is equivalent to DNA-directed 5'-3' RNA polymerase activity.
synonym: "DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter" EXACT []
+xref: Reactome:R-HSA-1964482 "RNA polymerase III transcribes microbial dsDNA to dsRNA"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23779" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
is_obsolete: true
@@ -9211,7 +9367,6 @@
synonym: "transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding" NARROW []
synonym: "transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding" NARROW []
synonym: "transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding" EXACT []
-xref: Reactome:R-HSA-8936851 "AHRR binds ARNT"
is_a: GO:0000981 ! DNA-binding transcription factor activity, RNA polymerase II-specific
is_a: GO:0001217 ! DNA-binding transcription repressor activity
intersection_of: GO:0140110 ! transcription regulator activity
@@ -9257,7 +9412,6 @@
synonym: "transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding" NARROW []
synonym: "transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding" EXACT []
synonym: "zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription" NARROW []
-xref: Reactome:R-HSA-8937177 "AHR:TCDD binds ARNT"
xref: Reactome:R-HSA-9856539 "MLXIPL:MLX binds PKLR gene promoter"
xref: Reactome:R-HSA-9856546 "MLXIPL:MLX binds FASN gene promoter"
xref: Reactome:R-HSA-9856548 "MLXIPL:MLX binds ACACB gene promoter"
@@ -9854,7 +10008,10 @@
xref: Reactome:R-HSA-8936519 "NQO2:FAD dimer reduces quinones to hydroquinones"
xref: RHEA:12364
is_a: GO:0016679 ! oxidoreductase activity, acting on diphenols and related substances as donors
+property_value: skos:exactMatch EC:1.10.5.1
+property_value: skos:exactMatch RHEA:12364
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0001514
@@ -9891,7 +10048,7 @@
def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate." [GOC:ai, GOC:hjd]
subset: goslim_chembl
synonym: "N-acetylglucosamine 6-O-sulphotransferase activity" EXACT []
-xref: Reactome:R-HSA-2046222 "CHST2,3,5,6 transfer sulfate to GlcNAc on keratan chain"
+xref: Reactome:R-HSA-2046222 "CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG"
xref: Reactome:R-HSA-3656269 "Defective CHST6 does not transfer SO4(2-) to GlcNAc residues on keratan-PG"
xref: Reactome:R-HSA-6786012 "CHST4 transfers SO4(2-) from PAPS to Core 2 mucins"
is_a: GO:0008146 ! sulfotransferase activity
@@ -9982,11 +10139,12 @@
id: GO:0001527
name: microfibril
namespace: cellular_component
-def: "Extracellular matrix components occurring independently or along with elastin. Thought to have force-bearing functions in tendon. In addition to fibrillins, microfibrils may contain other associated proteins." [PMID:27026396]
+def: "Extracellular matrix components occurring independently or along with elastin. Thought to have force-bearing functions in tendon. In addition to fibrillins, microfibrils may contain other associated proteins." [PMID:27026396, PMID:31226403]
synonym: "extended fibrils" EXACT []
synonym: "fibrillin" RELATED []
is_a: GO:0099512 ! supramolecular fiber
-relationship: part_of GO:0031012 ! extracellular matrix
+relationship: part_of GO:0071953 ! elastic fiber
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31132" xsd:anyURI
[Term]
id: GO:0001528
@@ -10089,6 +10247,8 @@
xref: Reactome:R-HSA-6786034 "CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin"
xref: RHEA:48052
is_a: GO:0120534 ! dermatan sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.35
+property_value: skos:exactMatch RHEA:48052
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28380" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29139" xsd:anyURI
@@ -10111,7 +10271,6 @@
def: "Binding to an amyloid-beta peptide/protein." [GOC:hjd]
subset: goslim_chembl
synonym: "beta-amyloid binding" EXACT []
-is_a: GO:0033218 ! amide binding
is_a: GO:0042277 ! peptide binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20109" xsd:anyURI
@@ -10388,6 +10547,8 @@
xref: RHEA:21104
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.38
+property_value: skos:exactMatch RHEA:21104
[Term]
id: GO:0001568
@@ -10573,9 +10734,10 @@
[Term]
id: GO:0001583
-name: detection of chemical stimulus involved in sensory perception of salty taste
+name: obsolete detection of chemical stimulus involved in sensory perception of salty taste
namespace: biological_process
-def: "The series of events required for a salty taste stimulus to be received and converted to a molecular signal." [GOC:go_curators]
+def: "OBSOLETE. The series of events required for a salty taste stimulus to be received and converted to a molecular signal." [GOC:go_curators]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "perception of salty taste, detection of chemical stimulus" EXACT []
synonym: "perception of salty taste, sensory transduction of chemical stimulus" EXACT []
synonym: "salty taste detection" EXACT []
@@ -10583,10 +10745,10 @@
synonym: "sensory detection of salty taste" EXACT []
synonym: "sensory transduction of chemical stimulus during perception of salty taste" EXACT []
synonym: "sensory transduction of salty taste" EXACT []
-is_a: GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste
-intersection_of: GO:0009593 ! detection of chemical stimulus
-intersection_of: part_of GO:0050914 ! sensory perception of salty taste
-relationship: part_of GO:0050914 ! sensory perception of salty taste
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0009593
+consider: GO:0050914
[Term]
id: GO:0001584
@@ -11221,6 +11383,9 @@
xref: Reactome:R-HSA-9846305 "ST6GALNAC5,6 transfer Neu5Ac to GM1b"
xref: RHEA:11136
is_a: GO:0008373 ! sialyltransferase activity
+property_value: skos:exactMatch EC:2.4.3.3
+property_value: skos:exactMatch RHEA:11136
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0001666
@@ -11348,8 +11513,10 @@
synonym: "N-acetylneuraminate acetyltransferase activity" RELATED []
xref: EC:3.1.1.53
is_a: GO:0008126 ! acetylesterase activity
+property_value: skos:exactMatch EC:3.1.1.53
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26015" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0001682
@@ -11665,6 +11832,9 @@
xref: Reactome:R-HSA-2160492 "IL4I1:FAD oxidises L-Phe to kPPV"
xref: RHEA:13781
is_a: GO:0008131 ! primary methylamine oxidase activity
+property_value: skos:exactMatch EC:1.4.3.2
+property_value: skos:exactMatch RHEA:13781
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0001717
@@ -11761,6 +11931,9 @@
xref: Reactome:R-HSA-1638845 "CERK phosphorylates CERA to form C1P"
xref: RHEA:17929
is_a: GO:0001727 ! lipid kinase activity
+property_value: skos:exactMatch EC:2.7.1.138
+property_value: skos:exactMatch RHEA:17929
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0001730
@@ -11778,6 +11951,9 @@
xref: Reactome:R-HSA-8985104 "OAS2 produces oligoadenylates"
xref: RHEA:34407
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.84
+property_value: skos:exactMatch RHEA:34407
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0001731
@@ -11820,7 +11996,14 @@
xref: MetaCyc:GALACTOSYLCERAMIDE-SULFOTRANSFERASE-RXN
xref: Reactome:R-HSA-9844587 "GAL3ST1 transfers sulfate to GalCer,LacCer"
xref: RHEA:20613
+xref: RHEA:41744
+xref: RHEA:43304
is_a: GO:0050694 ! galactose 3-O-sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.11
+property_value: skos:exactMatch RHEA:20613
+property_value: skos:narrowMatch RHEA:41744
+property_value: skos:narrowMatch RHEA:43304
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0001734
@@ -11833,7 +12016,10 @@
xref: Reactome:R-HSA-72095 "Internal Methylation of mRNA"
xref: RHEA:55584
is_a: GO:0008174 ! mRNA methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.348
+property_value: skos:exactMatch RHEA:55584
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27389" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0001735
@@ -11846,6 +12032,9 @@
xref: MetaCyc:RXN-18932
xref: RHEA:53892
is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.8.3.5
+property_value: skos:exactMatch RHEA:53892
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0001736
@@ -12047,6 +12236,9 @@
xref: Reactome:R-HSA-5696101 "ALDH8A1 oxidises 9cRAL to 9cRA"
xref: RHEA:16177
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.36
+property_value: skos:exactMatch RHEA:16177
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30270" xsd:anyURI
[Term]
@@ -12078,6 +12270,9 @@
xref: MetaCyc:AMINO-CARBOXYMUCONATE-SEMIALDEHYDE-RXN
xref: RHEA:16557
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.45
+property_value: skos:exactMatch RHEA:16557
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0001761
@@ -13504,10 +13699,12 @@
synonym: "UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity" RELATED [EC:2.4.1.223]
xref: EC:2.4.1.223
xref: MetaCyc:2.4.1.223-RXN
-xref: Reactome:R-HSA-9953259 "EXTL3 dimer transfers GlcNAc to the GAG linker"
xref: RHEA:16221
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.223
+property_value: skos:exactMatch RHEA:16221
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28762" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0001889
@@ -14846,23 +15043,25 @@
[Term]
id: GO:0002004
-name: secretion of vasopressin involved in fast regulation of systemic arterial blood pressure
+name: obsolete secretion of vasopressin involved in fast regulation of systemic arterial blood pressure
namespace: biological_process
-def: "The regulated release of the hormone vasopressin into the blood stream by the hypothalamus and pituitary gland contributing to fast regulation of blood pressure." [ISBN:0721643949]
+def: "OBSOLETE. The regulated release of the hormone vasopressin into the blood stream by the hypothalamus and pituitary gland contributing to fast regulation of blood pressure." [ISBN:0721643949]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "secretion of vasopressin during fast control of blood pressure" RELATED []
synonym: "secretion of vasopressin during fast regulation of systemic arterial blood pressure" RELATED [GOC:dph]
-is_a: GO:0030103 ! vasopressin secretion
-relationship: part_of GO:0001992 ! regulation of systemic arterial blood pressure by vasopressin
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0002006
-name: vasoconstriction by vasopressin involved in systemic arterial blood pressure control
+name: obsolete vasoconstriction by vasopressin involved in systemic arterial blood pressure control
namespace: biological_process
-def: "The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream." [GOC:dph, GOC:mtg_cardio, GOC:tb, ISBN:0721643949]
+def: "OBSOLETE. The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream." [GOC:dph, GOC:mtg_cardio, GOC:tb, ISBN:0721643949]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "vasopressin mediated vasoconstriction involved in systemic arterial blood pressure control" EXACT [GOC:dph, GOC:tb]
-is_a: GO:0003084 ! positive regulation of systemic arterial blood pressure
-is_a: GO:0042310 ! vasoconstriction
-relationship: part_of GO:0001992 ! regulation of systemic arterial blood pressure by vasopressin
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003084
[Term]
id: GO:0002007
@@ -15281,13 +15480,14 @@
[Term]
id: GO:0002045
-name: regulation of cell adhesion involved in intussusceptive angiogenesis
+name: obsolete regulation of cell adhesion involved in intussusceptive angiogenesis
namespace: biological_process
-def: "The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis." [PMID:16391003]
-is_a: GO:0030155 ! regulation of cell adhesion
-intersection_of: GO:0030155 ! regulation of cell adhesion
-intersection_of: part_of GO:0002041 ! intussusceptive angiogenesis
-relationship: part_of GO:0002041 ! intussusceptive angiogenesis
+def: "OBSOLETE. The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis." [PMID:16391003]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0002041
+consider: GO:0030155
[Term]
id: GO:0002046
@@ -15329,14 +15529,12 @@
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine." [PMID:15317763]
is_a: GO:0019290 ! siderophore biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
[Term]
id: GO:0002050
name: pyoverdine catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine." [PMID:15317763]
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0046215 ! siderophore catabolic process
[Term]
@@ -15559,7 +15757,7 @@
name: acrosome matrix dispersal
namespace: biological_process
def: "The proteolytic digestion of components in the acrosomal matrix that occurs as part of the acrosome reaction. The process can occur either in the cumulus oophorous facilitating the penetration of it by the sperm, or at the zona pellucida allowing the sperm to reach the plasma membrane of the egg where the inner acrosomal membrane of the sperm can interact with the egg plasma membrane." [GOC:dph, PMID:3886029]
-is_a: GO:0051603 ! proteolysis involved in protein catabolic process
+is_a: GO:0030163 ! protein catabolic process
relationship: part_of GO:0007340 ! acrosome reaction
[Term]
@@ -15617,6 +15815,7 @@
namespace: molecular_function
def: "OBSOLETE. Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate." [GOC:curators]
comment: This term was obsoleted because it represents a specific substrate of 4-hydroxybenzoate polyprenyltransferase activity ; GO:0008412.
+xref: Reactome:R-HSA-2162192 "COQ2 ligates all-E-10PrP2 to PHB"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26830" xsd:anyURI
is_obsolete: true
replaced_by: GO:0008412
@@ -16174,6 +16373,8 @@
xref: MetaCyc:RXN0-3543
xref: RHEA:27914
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch RHEA:27914
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2009-06-10T11:21:35Z
@@ -17167,12 +17368,13 @@
[Term]
id: GO:0002247
-name: clearance of damaged tissue involved in inflammatory response wound healing
+name: obsolete clearance of damaged tissue involved in inflammatory response wound healing
namespace: biological_process
-def: "The series of events leading to removal of necrotic debris that contribute to an inflammatory response." [GOC:jal, ISBN:0721601871]
+def: "OBSOLETE. The series of events leading to removal of necrotic debris that contribute to an inflammatory response." [GOC:jal, ISBN:0721601871]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "clearance of damaged tissue during inflammatory response" RELATED [GOC:dph]
-is_a: GO:0048771 ! tissue remodeling
-relationship: part_of GO:0002246 ! wound healing involved in inflammatory response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0002248
@@ -17290,11 +17492,13 @@
[Term]
id: GO:0002259
-name: endothelial cell activation within high endothelial venule involved in immune response
+name: obsolete endothelial cell activation within high endothelial venule involved in immune response
namespace: biological_process
-def: "A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149]
+def: "OBSOLETE. A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "endothelial cell activation within high endothelial venule during immune response" RELATED [GOC:tb]
-is_a: GO:0002264 ! endothelial cell activation involved in immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0002260
@@ -17361,14 +17565,15 @@
[Term]
id: GO:0002267
-name: follicular dendritic cell activation involved in immune response
+name: obsolete follicular dendritic cell activation involved in immune response
namespace: biological_process
-def: "A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, PMID:15606789]
+def: "OBSOLETE. A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, PMID:15606789]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "follicular dendritic cell activation during immune response" RELATED [GOC:tb]
-is_a: GO:0002263 ! cell activation involved in immune response
-is_a: GO:0002266 ! follicular dendritic cell activation
-intersection_of: GO:0002266 ! follicular dendritic cell activation
-intersection_of: part_of GO:0006955 ! immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0002266
+consider: GO:0006955
[Term]
id: GO:0002268
@@ -17410,14 +17615,15 @@
[Term]
id: GO:0002272
-name: plasmacytoid dendritic cell differentiation involved in immune response
+name: obsolete plasmacytoid dendritic cell differentiation involved in immune response
namespace: biological_process
-def: "The process in which an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response." [GOC:add, PMID:15990333]
+def: "OBSOLETE. The process in which an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response." [GOC:add, PMID:15990333]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "plasmacytoid dendritic cell differentiation during immune response" RELATED [GOC:dph]
-is_a: GO:0002271 ! plasmacytoid dendritic cell activation involved in immune response
-is_a: GO:0002273 ! plasmacytoid dendritic cell differentiation
-intersection_of: GO:0002273 ! plasmacytoid dendritic cell differentiation
-intersection_of: part_of GO:0006955 ! immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0002273
+consider: GO:0006955
[Term]
id: GO:0002273
@@ -17537,14 +17743,15 @@
[Term]
id: GO:0002284
-name: myeloid dendritic cell differentiation involved in immune response
+name: obsolete myeloid dendritic cell differentiation involved in immune response
namespace: biological_process
-def: "The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response." [GOC:add, ISBN:0781735149]
+def: "OBSOLETE. The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response." [GOC:add, ISBN:0781735149]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "myeloid dendritic cell differentiation during immune response" RELATED [GOC:tb]
-is_a: GO:0002277 ! myeloid dendritic cell activation involved in immune response
-is_a: GO:0043011 ! myeloid dendritic cell differentiation
-intersection_of: GO:0043011 ! myeloid dendritic cell differentiation
-intersection_of: part_of GO:0006955 ! immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0006955
+consider: GO:0043011
[Term]
id: GO:0002285
@@ -17797,20 +18004,19 @@
[Term]
id: GO:0002303
-name: gamma-delta T cell differentiation involved in immune response
+name: obsolete gamma-delta T cell differentiation involved in immune response
namespace: biological_process
-def: "The process in which an antigenically naive gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." [GOC:add]
-comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
+def: "OBSOLETE. The process in which an antigenically naive gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." [GOC:add]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "gamma-delta T cell development involved in immune response" RELATED [GOC:add]
synonym: "gamma-delta T cell differentiation during immune response" RELATED [GOC:dph]
synonym: "gamma-delta T lymphocyte differentiation during immune response" RELATED []
synonym: "gamma-delta T-cell differentiation during immune response" RELATED []
synonym: "gamma-delta T-lymphocyte differentiation during immune response" RELATED []
-is_a: GO:0002290 ! gamma-delta T cell activation involved in immune response
-is_a: GO:0002292 ! T cell differentiation involved in immune response
-is_a: GO:0042492 ! gamma-delta T cell differentiation
-intersection_of: GO:0042492 ! gamma-delta T cell differentiation
-intersection_of: part_of GO:0006955 ! immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0006955
+consider: GO:0042492
[Term]
id: GO:0002304
@@ -17905,18 +18111,18 @@
[Term]
id: GO:0002311
-name: gamma-delta T cell proliferation involved in immune response
+name: obsolete gamma-delta T cell proliferation involved in immune response
namespace: biological_process
-def: "The expansion of a gamma-delta T cell population by cell division as part of an immune response." [GOC:add]
+def: "OBSOLETE. The expansion of a gamma-delta T cell population by cell division as part of an immune response." [GOC:add]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "gamma-delta T cell proliferation during immune response" RELATED [GOC:tb]
synonym: "gamma-delta T lymphocyte proliferation during immune response" RELATED []
synonym: "gamma-delta T-cell proliferation during immune response" RELATED []
synonym: "gamma-delta T-lymphocyte proliferation during immune response" RELATED []
-is_a: GO:0002290 ! gamma-delta T cell activation involved in immune response
-is_a: GO:0002309 ! T cell proliferation involved in immune response
-is_a: GO:0046630 ! gamma-delta T cell proliferation
-intersection_of: GO:0046630 ! gamma-delta T cell proliferation
-intersection_of: part_of GO:0006955 ! immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0006955
+consider: GO:0046630
[Term]
id: GO:0002312
@@ -18715,22 +18921,23 @@
[Term]
id: GO:0002391
-name: platelet activating factor production involved in inflammatory response
+name: obsolete platelet activating factor production involved in inflammatory response
namespace: biological_process
alt_id: GO:0002390
alt_id: GO:0002392
alt_id: GO:0002535
-def: "The synthesis or release of platelet activating factor following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149]
+def: "OBSOLETE. The synthesis or release of platelet activating factor following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "platelet activating factor production" RELATED []
synonym: "platelet activating factor production involved in acute inflammatory response" NARROW []
synonym: "platelet activating factor secretion" NARROW []
synonym: "platelet activating factor secretion involved in acute inflammatory response" NARROW []
synonym: "platelet activating factor secretion involved in inflammatory response" NARROW []
-is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response
-intersection_of: GO:0002532 ! production of molecular mediator involved in inflammatory response
-intersection_of: has_part GO:0006663 ! platelet activating factor biosynthetic process
-relationship: has_part GO:0006663 ! platelet activating factor biosynthetic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20154" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0002532
+consider: GO:000666
[Term]
id: GO:0002393
@@ -19669,7 +19876,7 @@
name: proteolysis associated with antigen processing and presentation
namespace: biological_process
def: "The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation." [GOC:add, ISBN:0781735149, PMID:15224092, PMID:15771591]
-is_a: GO:0051603 ! proteolysis involved in protein catabolic process
+is_a: GO:0006508 ! proteolysis
intersection_of: GO:0006508 ! proteolysis
intersection_of: part_of GO:0048002 ! antigen processing and presentation of peptide antigen
relationship: part_of GO:0048002 ! antigen processing and presentation of peptide antigen
@@ -19954,14 +20161,15 @@
[Term]
id: GO:0002527
-name: vasodilation involved in acute inflammatory response
+name: obsolete vasodilation involved in acute inflammatory response
namespace: biological_process
-def: "An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response." [GOC:jal]
+def: "OBSOLETE. An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response." [GOC:jal]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "vasodilation during acute inflammatory response" RELATED [GOC:dph]
-is_a: GO:0042311 ! vasodilation
-intersection_of: GO:0042311 ! vasodilation
-intersection_of: part_of GO:0002526 ! acute inflammatory response
-relationship: part_of GO:0002526 ! acute inflammatory response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0002526
+consider: GO:0042311
[Term]
id: GO:0002528
@@ -19986,27 +20194,29 @@
[Term]
id: GO:0002530
-name: regulation of systemic arterial blood pressure involved in acute-phase response
+name: obsolete regulation of systemic arterial blood pressure involved in acute-phase response
namespace: biological_process
-def: "Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein." [GOC:jal, ISBN:081533642X]
+def: "OBSOLETE. Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein." [GOC:jal, ISBN:081533642X]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "blood pressure regulation during acute phase response" RELATED []
synonym: "regulation of systemic arterial blood pressure during acute phase response" RELATED [GOC:tb]
-is_a: GO:0003073 ! regulation of systemic arterial blood pressure
-intersection_of: GO:0003073 ! regulation of systemic arterial blood pressure
-intersection_of: part_of GO:0006953 ! acute-phase response
-relationship: part_of GO:0006953 ! acute-phase response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003073
+consider: GO:0006953
[Term]
id: GO:0002531
-name: regulation of heart contraction involved in acute-phase response
+name: obsolete regulation of heart contraction involved in acute-phase response
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein." [GOC:jal, PMID:15642986, PMID:15834430]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein." [GOC:jal, PMID:15642986, PMID:15834430]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "regulation of cardiac contraction during acute phase response" RELATED []
synonym: "regulation of heart contraction during acute phase response" RELATED [GOC:tb]
-is_a: GO:0008016 ! regulation of heart contraction
-intersection_of: GO:0008016 ! regulation of heart contraction
-intersection_of: part_of GO:0006953 ! acute-phase response
-relationship: part_of GO:0006953 ! acute-phase response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0006953
+consider: GO:0008016
[Term]
id: GO:0002532
@@ -20020,16 +20230,17 @@
[Term]
id: GO:0002533
-name: lysosomal enzyme secretion involved in inflammatory response
+name: obsolete lysosomal enzyme secretion involved in inflammatory response
namespace: biological_process
-def: "The regulated release of lysosomal enzymes by a cell as part of an inflammatory response." [GOC:jal, PMID:11836514]
+def: "OBSOLETE. The regulated release of lysosomal enzymes by a cell as part of an inflammatory response." [GOC:jal, PMID:11836514]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "lysosomal enzyme secretion involved in acute inflammatory response" RELATED [GOC:mah]
synonym: "secretion of lysosomal enzymes involved in acute inflammatory response" BROAD []
synonym: "secretion of lysosomal enzymes involved in inflammatory response" EXACT []
-is_a: GO:0033299 ! secretion of lysosomal enzymes
-intersection_of: GO:0033299 ! secretion of lysosomal enzymes
-intersection_of: part_of GO:0006954 ! inflammatory response
-relationship: part_of GO:0002393 ! lysosomal enzyme production involved in inflammatory response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0006954
+consider: GO:0033299
[Term]
id: GO:0002534
@@ -21190,7 +21401,7 @@
name: regulation of proteolysis associated with antigen processing and presentation
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation." [GOC:add]
-is_a: GO:1903050 ! regulation of proteolysis involved in protein catabolic process
+is_a: GO:0030162 ! regulation of proteolysis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002496 ! proteolysis associated with antigen processing and presentation
relationship: regulates GO:0002496 ! proteolysis associated with antigen processing and presentation
@@ -21207,7 +21418,7 @@
is_a: GO:0002584 ! negative regulation of antigen processing and presentation of peptide antigen
is_a: GO:0002628 ! regulation of proteolysis associated with antigen processing and presentation
is_a: GO:0042177 ! negative regulation of protein catabolic process
-is_a: GO:1903051 ! negative regulation of proteolysis involved in protein catabolic process
+is_a: GO:0045861 ! negative regulation of proteolysis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002496 ! proteolysis associated with antigen processing and presentation
relationship: negatively_regulates GO:0002496 ! proteolysis associated with antigen processing and presentation
@@ -21226,7 +21437,7 @@
is_a: GO:0002585 ! positive regulation of antigen processing and presentation of peptide antigen
is_a: GO:0002628 ! regulation of proteolysis associated with antigen processing and presentation
is_a: GO:0045732 ! positive regulation of protein catabolic process
-is_a: GO:1903052 ! positive regulation of proteolysis involved in protein catabolic process
+is_a: GO:0045862 ! positive regulation of proteolysis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002496 ! proteolysis associated with antigen processing and presentation
relationship: positively_regulates GO:0002496 ! proteolysis associated with antigen processing and presentation
@@ -25428,6 +25639,8 @@
xref: RHEA:43332
is_a: GO:0008169 ! C-methyltransferase activity
is_a: GO:0016426 ! tRNA (adenine) methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.192
+property_value: skos:exactMatch RHEA:43332
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/9902" xsd:anyURI
created_by: hjd
creation_date: 2012-09-04T14:39:56Z
@@ -25438,7 +25651,6 @@
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin." [PMID:11226291]
is_a: GO:0043043 ! peptide biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
created_by: hjd
creation_date: 2012-10-17T14:24:24Z
@@ -25560,7 +25772,10 @@
xref: RHEA:54084
xref: Wikipedia:Archaeosine_synthase
is_a: GO:0016769 ! transferase activity, transferring nitrogenous groups
+property_value: skos:exactMatch EC:2.6.1.97
+property_value: skos:exactMatch RHEA:54084
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2014-08-11T10:33:59Z
@@ -25590,23 +25805,31 @@
def: "Catalysis of the reaction: an N-acyl-sphingoid base + CDP-ethanolamine = an N-acyl-sphingoid 1-phosphoethanolamine + CMP + H+." [EC:2.7.8.48, PMID:25667419]
xref: EC:2.7.8.48
xref: Reactome:R-HSA-8959462 "SAMD8 transfers phosphatidyl from PE onto C16DH CER"
+xref: RHEA:45892
xref: RHEA:45896
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.48
+property_value: skos:exactMatch RHEA:45896
+property_value: skos:narrowMatch RHEA:45892
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23370" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27352" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2016-08-16T13:41:21Z
[Term]
id: GO:0002951
-name: leukotriene-C(4) hydrolase
+name: leukotriene-C(4) hydrolase activity
namespace: molecular_function
def: "Catalysis of the reaction leukotriene C(4) + H2O= leukotriene D(4) + L-glutamate." [PMID:9774450, RHEA:31563]
comment: The mouse enzyme is specific for leukotriene C(4), while the human enzyme also has considerable activity toward glutathione and oxidized glutathione (cf. EC:3.4.19.13). PMID:9774450 cites that the mouse form of this enzyme failed to measure activity towards glutathione.
xref: EC:3.4.19.14
xref: RHEA:31563
is_a: GO:0008242 ! omega peptidase activity
+property_value: skos:exactMatch EC:3.4.19.14
+property_value: skos:exactMatch RHEA:31563
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23253" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0002952
@@ -25618,6 +25841,9 @@
xref: MetaCyc:RXN-15216
xref: RHEA:44360
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.32
+property_value: skos:exactMatch MetaCyc:RXN-15216
+property_value: skos:exactMatch RHEA:44360
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
[Term]
@@ -25628,7 +25854,10 @@
xref: EC:3.1.3.89
xref: RHEA:36167
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.89
+property_value: skos:exactMatch RHEA:36167
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27990" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003001
@@ -25655,36 +25884,39 @@
[Term]
id: GO:0003003
-name: follicular fluid formation in ovarian follicle antrum involved in fused antrum stage
+name: obsolete follicular fluid formation in ovarian follicle antrum involved in fused antrum stage
namespace: biological_process
-def: "The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis." [GOC:dph, GOC:isa_complete]
+def: "OBSOLETE. The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis." [GOC:dph, GOC:isa_complete]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "follicular fluid formation in ovarian follicle antrum during fused antrum stage" RELATED [GOC:dph, GOC:tb]
-is_a: GO:0001548 ! follicular fluid formation in ovarian follicle antrum
-intersection_of: GO:0001548 ! follicular fluid formation in ovarian follicle antrum
-intersection_of: part_of GO:0048165 ! fused antrum stage
-relationship: part_of GO:0048165 ! fused antrum stage
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001548
+consider: GO:0048165
[Term]
id: GO:0003004
-name: follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage
+name: obsolete follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage
namespace: biological_process
-def: "The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis." [GOC:dph, GOC:isa_complete]
+def: "OBSOLETE. The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis." [GOC:dph, GOC:isa_complete]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "follicular fluid formation in ovarian follicle antrum during distinct antral spaces stage" RELATED [GOC:dph, GOC:tb]
-is_a: GO:0001548 ! follicular fluid formation in ovarian follicle antrum
-intersection_of: GO:0001548 ! follicular fluid formation in ovarian follicle antrum
-intersection_of: part_of GO:0048164 ! distinct antral spaces stage
-relationship: part_of GO:0048164 ! distinct antral spaces stage
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001548
+consider: GO:0048164
[Term]
id: GO:0003005
-name: follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage
+name: obsolete follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage
namespace: biological_process
-def: "The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis." [GOC:dph, GOC:isa_complete]
+def: "OBSOLETE. The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis." [GOC:dph, GOC:isa_complete]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "follicular fluid formation in ovarian follicle antrum during scattered antral spaces stage" RELATED [GOC:dph, GOC:tb]
-is_a: GO:0001548 ! follicular fluid formation in ovarian follicle antrum
-intersection_of: GO:0001548 ! follicular fluid formation in ovarian follicle antrum
-intersection_of: part_of GO:0048163 ! scattered antral spaces stage
-relationship: part_of GO:0048163 ! scattered antral spaces stage
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001548
+consider: GO:0048163
[Term]
id: GO:0003006
@@ -26003,21 +26235,23 @@
[Term]
id: GO:0003042
-name: vasoconstriction of artery involved in carotid body chemoreceptor response to lowering of systemic arterial blood pressure
+name: obsolete vasoconstriction of artery involved in carotid body chemoreceptor response to lowering of systemic arterial blood pressure
namespace: biological_process
-def: "A process that is triggered by carotid body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure." [ISBN:0323031951]
+def: "OBSOLETE. A process that is triggered by carotid body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure." [ISBN:0323031951]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "vasoconstriction of artery during carotid body chemoreceptor response to lowering of systemic arterial blood pressure" RELATED [GOC:dph]
-is_a: GO:0002012 ! vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure
-relationship: part_of GO:0003027 ! regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0003043
-name: vasoconstriction of artery involved in aortic body chemoreceptor response to lowering of systemic arterial blood pressure
+name: obsolete vasoconstriction of artery involved in aortic body chemoreceptor response to lowering of systemic arterial blood pressure
namespace: biological_process
-def: "A process that is triggered by aortic body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure." [GOC:mtg_cardio]
+def: "OBSOLETE. A process that is triggered by aortic body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure." [GOC:mtg_cardio]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "vasoconstriction of artery during aortic body chemoreceptor response to lowering of systemic arterial blood pressure" RELATED [GOC:dph]
-is_a: GO:0002012 ! vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure
-relationship: part_of GO:0003028 ! regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0003044
@@ -26327,11 +26561,13 @@
[Term]
id: GO:0003075
-name: renal vasodilation of the peripheral vascular system involved in regulation of systemic arterial blood pressure
+name: obsolete renal vasodilation of the peripheral vascular system involved in regulation of systemic arterial blood pressure
namespace: biological_process
-def: "The renal process that modulates the force with which blood travels through the circulatory system, by vasodilation of the peripheral vascular system." [GOC:mtg_cardio]
+def: "OBSOLETE. The renal process that modulates the force with which blood travels through the circulatory system, by vasodilation of the peripheral vascular system." [GOC:mtg_cardio]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "renal regulation of systemic arterial blood pressure by vasodilation of the peripheral vascular system" EXACT [GOC:dph, GOC:tb]
-is_a: GO:0003072 ! renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0003077
@@ -26824,14 +27060,15 @@
[Term]
id: GO:0003132
-name: mesodermal-endodermal cell signaling involved in heart induction
+name: obsolete mesodermal-endodermal cell signaling involved in heart induction
namespace: biological_process
-def: "Any process that mediates the transfer of information from mesodermal cells to endodermal cells that contributes to heart induction." [GOC:mtg_heart]
+def: "OBSOLETE. Any process that mediates the transfer of information from mesodermal cells to endodermal cells that contributes to heart induction." [GOC:mtg_heart]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "mesodermal-endodermal cell signalling involved in heart induction" EXACT [GOC:mah]
-is_a: GO:0003131 ! mesodermal-endodermal cell signaling
-intersection_of: GO:0003131 ! mesodermal-endodermal cell signaling
-intersection_of: part_of GO:0003129 ! heart induction
-relationship: part_of GO:0003129 ! heart induction
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003129
+consider: GO:0003131
created_by: tb
creation_date: 2009-09-22T03:08:52Z
@@ -26847,14 +27084,15 @@
[Term]
id: GO:0003134
-name: endodermal-mesodermal cell signaling involved in heart induction
+name: obsolete endodermal-mesodermal cell signaling involved in heart induction
namespace: biological_process
-def: "Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction." [GOC:mtg_heart]
+def: "OBSOLETE. Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction." [GOC:mtg_heart]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "endodermal-mesodermal cell signalling involved in heart induction" EXACT [GOC:mah]
-is_a: GO:0003133 ! endodermal-mesodermal cell signaling
-intersection_of: GO:0003133 ! endodermal-mesodermal cell signaling
-intersection_of: part_of GO:0003129 ! heart induction
-relationship: part_of GO:0003129 ! heart induction
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003129
+consider: GO:0003133
created_by: tb
creation_date: 2009-09-22T03:11:17Z
@@ -27573,13 +27811,14 @@
[Term]
id: GO:0003200
-name: endocardial cushion to mesenchymal transition involved in heart chamber septation
+name: obsolete endocardial cushion to mesenchymal transition involved in heart chamber septation
namespace: biological_process
-def: "A transition where an endocardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the heart septum." [GOC:mtg_heart]
-is_a: GO:0090500 ! endocardial cushion to mesenchymal transition
-intersection_of: GO:0090500 ! endocardial cushion to mesenchymal transition
-intersection_of: part_of GO:0060411 ! cardiac septum morphogenesis
-relationship: part_of GO:0060411 ! cardiac septum morphogenesis
+def: "OBSOLETE. A transition where an endocardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the heart septum." [GOC:mtg_heart]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060411
+consider: GO:0090500
created_by: dph
creation_date: 2009-10-08T01:34:31Z
@@ -27597,13 +27836,14 @@
[Term]
id: GO:0003202
-name: endocardial cushion to mesenchymal transition involved in cardiac skeleton development
+name: obsolete endocardial cushion to mesenchymal transition involved in cardiac skeleton development
namespace: biological_process
-def: "A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will give rise to the cardiac skeleton." [GOC:mtg_heart]
-is_a: GO:0090500 ! endocardial cushion to mesenchymal transition
-intersection_of: GO:0090500 ! endocardial cushion to mesenchymal transition
-intersection_of: part_of GO:0003204 ! cardiac skeleton development
-relationship: part_of GO:0003204 ! cardiac skeleton development
+def: "OBSOLETE. A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will give rise to the cardiac skeleton." [GOC:mtg_heart]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003204
+consider: GO:0090500
created_by: dph
creation_date: 2009-10-08T01:39:57Z
@@ -28021,11 +28261,12 @@
[Term]
id: GO:0003244
-name: radial growth involved in right ventricle morphogenesis
+name: obsolete radial growth involved in right ventricle morphogenesis
namespace: biological_process
-def: "The morphogenic growth in which the right ventricle grows along a radial axis." [GOC:mtg_heart]
-is_a: GO:0003241 ! growth involved in heart morphogenesis
-relationship: part_of GO:0003215 ! cardiac right ventricle morphogenesis
+def: "OBSOLETE. The morphogenic growth in which the right ventricle grows along a radial axis." [GOC:mtg_heart]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2009-10-13T11:38:23Z
@@ -28044,13 +28285,13 @@
[Term]
id: GO:0003246
-name: embryonic cardiac muscle cell growth involved in heart morphogenesis
+name: obsolete embryonic cardiac muscle cell growth involved in heart morphogenesis
namespace: biological_process
-def: "The growth of a cardiac muscle cell during the embryonic period, that contributes to the shaping of the heart." [GOC:mtg_heart]
+def: "OBSOLETE. The growth of a cardiac muscle cell during the embryonic period, that contributes to the shaping of the heart." [GOC:mtg_heart]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "embryonic cardiac muscle physiological hypertrophy" EXACT [GOC:mtg_heart]
-is_a: GO:0003241 ! growth involved in heart morphogenesis
-is_a: GO:0061049 ! cell growth involved in cardiac muscle cell development
-relationship: part_of GO:0003245 ! cardiac muscle tissue growth involved in heart morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2009-10-13T11:46:23Z
@@ -28404,14 +28645,15 @@
[Term]
id: GO:0003276
-name: apoptotic process involved in heart valve morphogenesis
+name: obsolete apoptotic process involved in heart valve morphogenesis
namespace: biological_process
-def: "Any apoptotic process that contributes to the shaping of a heart valve." [GOC:mtg_apoptosis, GOC:mtg_heart]
+def: "OBSOLETE. Any apoptotic process that contributes to the shaping of a heart valve." [GOC:mtg_apoptosis, GOC:mtg_heart]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "apoptosis involved in heart valve morphogenesis" NARROW []
-is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis
-intersection_of: GO:0006915 ! apoptotic process
-intersection_of: part_of GO:0003179 ! heart valve morphogenesis
-relationship: part_of GO:0003179 ! heart valve morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003179
+consider: GO:0006915
created_by: dph
creation_date: 2009-10-20T09:34:29Z
@@ -28584,35 +28826,37 @@
[Term]
id: GO:0003295
-name: cell proliferation involved in atrial ventricular junction remodeling
+name: obsolete cell proliferation involved in atrial ventricular junction remodeling
namespace: biological_process
-def: "The multiplication or reproduction of cells that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction." [GOC:mtg_heart]
+def: "OBSOLETE. The multiplication or reproduction of cells that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction." [GOC:mtg_heart]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "cell proliferation involved in atrial ventricular junction remodelling" EXACT []
synonym: "cell proliferation involved in atrio-ventricular junction remodeling" EXACT [GOC:mtg_heart]
synonym: "cell proliferation involved in atrio-ventricular junction remodelling" EXACT []
synonym: "cell proliferation involved in atrioventricular junction remodeling" EXACT [GOC:mtg_heart]
synonym: "cell proliferation involved in atrioventricular junction remodelling" EXACT []
-is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis
-intersection_of: GO:0008283 ! cell population proliferation
-intersection_of: part_of GO:0003294 ! atrial ventricular junction remodeling
-relationship: part_of GO:0003294 ! atrial ventricular junction remodeling
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003294
+consider: GO:0008283
created_by: dph
creation_date: 2009-10-22T08:38:30Z
[Term]
id: GO:0003296
-name: apoptotic process involved in atrial ventricular junction remodeling
+name: obsolete apoptotic process involved in atrial ventricular junction remodeling
namespace: biological_process
-def: "Any apoptotic process that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction." [GOC:mtg_apoptosis, GOC:mtg_heart]
+def: "OBSOLETE. Any apoptotic process that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction." [GOC:mtg_apoptosis, GOC:mtg_heart]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "apoptosis involved in atrial ventricular junction remodelling" EXACT []
synonym: "apoptosis involved in atrio-ventricular junction remodeling" EXACT [GOC:mtg_heart]
synonym: "apoptosis involved in atrio-ventricular junction remodelling" EXACT []
synonym: "apoptosis involved in atrioventricular junction remodeling" EXACT [GOC:mtg_heart]
synonym: "apoptosis involved in atrioventricular junction remodelling" EXACT []
-is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis
-intersection_of: GO:0006915 ! apoptotic process
-intersection_of: part_of GO:0003294 ! atrial ventricular junction remodeling
-relationship: part_of GO:0003294 ! atrial ventricular junction remodeling
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003294
+consider: GO:0006915
created_by: dph
creation_date: 2009-10-22T08:43:11Z
@@ -28695,11 +28939,12 @@
[Term]
id: GO:0003304
-name: myocardial epithelial involution involved in heart jogging
+name: obsolete myocardial epithelial involution involved in heart jogging
namespace: biological_process
-def: "The morphogenetic process in which the myocardium bends along a linear axis and contributes to the process of heart jogging." [GOC:mtg_heart]
-is_a: GO:0060571 ! morphogenesis of an epithelial fold
-relationship: part_of GO:0003146 ! heart jogging
+def: "OBSOLETE. The morphogenetic process in which the myocardium bends along a linear axis and contributes to the process of heart jogging." [GOC:mtg_heart]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2009-10-22T11:03:33Z
@@ -28792,8 +29037,7 @@
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph, PMID:11076772]
synonym: "pancreatic delta cell differentiation" EXACT [GOC:dph]
-is_a: GO:0035883 ! enteroendocrine cell differentiation
-is_a: GO:0061101 ! neuroendocrine cell differentiation
+is_a: GO:7770025 ! intestinal type D enteroendocrine cell differentiation
relationship: part_of GO:0031018 ! endocrine pancreas development
created_by: dph
creation_date: 2009-10-26T09:30:27Z
@@ -29380,13 +29624,14 @@
[Term]
id: GO:0003362
-name: noradrenergic neuron fate commitment involved in brainstem development
+name: obsolete noradrenergic neuron fate commitment involved in brainstem development
namespace: biological_process
-def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem." [GOC:dph]
-is_a: GO:0003359 ! noradrenergic neuron fate commitment
-intersection_of: GO:0003359 ! noradrenergic neuron fate commitment
-intersection_of: part_of GO:0003360 ! brainstem development
-relationship: part_of GO:0003361 ! noradrenergic neuron differentiation involved in brainstem development
+def: "OBSOLETE. The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem." [GOC:dph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003359
+consider: GO:0003360
created_by: dph
creation_date: 2009-12-03T10:56:16Z
@@ -29404,14 +29649,14 @@
[Term]
id: GO:0003364
-name: lamellipodium assembly involved in mesendodermal cell migration
+name: obsolete lamellipodium assembly involved in mesendodermal cell migration
namespace: biological_process
-def: "Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self-propelled movement of a mesendodermal cell." [GOC:ascb_2009, GOC:dph, GOC:tb]
-is_a: GO:0003363 ! lamellipodium assembly involved in ameboidal cell migration
-is_a: GO:0010927 ! cellular component assembly involved in morphogenesis
-intersection_of: GO:0030032 ! lamellipodium assembly
-intersection_of: part_of GO:0090134 ! cell migration involved in mesendoderm migration
-relationship: part_of GO:0090134 ! cell migration involved in mesendoderm migration
+def: "OBSOLETE. Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self-propelled movement of a mesendodermal cell." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0030032
+consider: GO:0090134
created_by: dph
creation_date: 2009-12-08T04:46:39Z
@@ -29453,13 +29698,14 @@
[Term]
id: GO:0003368
-name: cell-matrix adhesion involved in mesendodermal cell migration
+name: obsolete cell-matrix adhesion involved in mesendodermal cell migration
namespace: biological_process
-def: "The binding of a cell to the extracellular matrix that contributes to the directed movement of a mesendodermal cell." [GOC:ascb_2009, GOC:dph, GOC:tb]
-is_a: GO:0003366 ! cell-matrix adhesion involved in ameboidal cell migration
-intersection_of: GO:0007160 ! cell-matrix adhesion
-intersection_of: part_of GO:0090134 ! cell migration involved in mesendoderm migration
-relationship: part_of GO:0090134 ! cell migration involved in mesendoderm migration
+def: "OBSOLETE. The binding of a cell to the extracellular matrix that contributes to the directed movement of a mesendodermal cell." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007160
+consider: GO:0090134
created_by: dph
creation_date: 2009-12-08T05:26:12Z
@@ -29502,13 +29748,14 @@
[Term]
id: GO:0003372
-name: establishment or maintenance of cytoskeleton polarity involved in mesendodermal cell migration
+name: obsolete establishment or maintenance of cytoskeleton polarity involved in mesendodermal cell migration
namespace: biological_process
-def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating mesendodermal cell." [GOC:ascb_2009, GOC:dph, GOC:tb]
-is_a: GO:0003380 ! establishment or maintenance of cytoskeleton polarity involved in gastrulation
-intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity
-intersection_of: part_of GO:0090134 ! cell migration involved in mesendoderm migration
-relationship: part_of GO:0003369 ! establishment of cell polarity involved in mesendodermal cell migration
+def: "OBSOLETE. Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating mesendodermal cell." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0030952
+consider: GO:0090134
created_by: dph
creation_date: 2009-12-08T05:46:23Z
@@ -29780,25 +30027,27 @@
[Term]
id: GO:0003396
-name: cell adhesion involved in amphid sensory organ dendrite retrograde extension
+name: obsolete cell adhesion involved in amphid sensory organ dendrite retrograde extension
namespace: biological_process
-def: "The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite in a neuron of the amphid sensory organ." [GOC:ascb_2009, GOC:dph, GOC:tb]
-is_a: GO:0003394 ! cell adhesion involved in dendrite retrograde extension
-intersection_of: GO:0007155 ! cell adhesion
-intersection_of: part_of GO:0003391 ! amphid sensory organ dendrite retrograde extension
-relationship: part_of GO:0003391 ! amphid sensory organ dendrite retrograde extension
+def: "OBSOLETE. The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite in a neuron of the amphid sensory organ." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003391
+consider: GO:0007155
created_by: dph
creation_date: 2009-12-09T09:50:18Z
[Term]
id: GO:0003397
-name: neuron migration involved in amphid sensory organ dendrite retrograde extension
+name: obsolete neuron migration involved in amphid sensory organ dendrite retrograde extension
namespace: biological_process
-def: "The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite of a neuron in the amphid sensory organ." [GOC:ascb_2009, GOC:dph, GOC:tb]
-is_a: GO:0003395 ! neuron migration involved in dendrite retrograde extension
-intersection_of: GO:0001764 ! neuron migration
-intersection_of: part_of GO:0003391 ! amphid sensory organ dendrite retrograde extension
-relationship: part_of GO:0003391 ! amphid sensory organ dendrite retrograde extension
+def: "OBSOLETE. The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite of a neuron in the amphid sensory organ." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001764
+consider: GO:0003391
created_by: dph
creation_date: 2009-12-09T09:52:18Z
@@ -29943,13 +30192,14 @@
[Term]
id: GO:0003411
-name: cell motility involved in camera-type eye morphogenesis
+name: obsolete cell motility involved in camera-type eye morphogenesis
namespace: biological_process
-def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb]
-is_a: GO:0048870 ! cell motility
-intersection_of: GO:0048870 ! cell motility
-intersection_of: part_of GO:0048593 ! camera-type eye morphogenesis
-relationship: part_of GO:0048593 ! camera-type eye morphogenesis
+def: "OBSOLETE. Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0048593
+consider: GO:0048870
created_by: dph
creation_date: 2009-12-21T03:04:27Z
@@ -30098,14 +30348,14 @@
[Term]
id: GO:0003425
-name: establishment of mitotic spindle orientation involved in growth plate cartilage chondrocyte division
+name: obsolete establishment of mitotic spindle orientation involved in growth plate cartilage chondrocyte division
namespace: biological_process
-def: "A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures and contributes to oriented chondrocyte division in the growth plate." [GOC:ascb_2009, GOC:dph, GOC:tb]
-is_a: GO:0000132 ! establishment of mitotic spindle orientation
-is_a: GO:0003426 ! cytoskeleton polarization involved in growth plate cartilage chondrocyte division
-is_a: GO:0090176 ! microtubule cytoskeleton organization involved in establishment of planar polarity
-intersection_of: GO:0051294 ! establishment of spindle orientation
-intersection_of: part_of GO:0003423 ! growth plate cartilage chondrocyte division
+def: "OBSOLETE. A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures and contributes to oriented chondrocyte division in the growth plate." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003423
+consider: GO:0051294
created_by: dph
creation_date: 2009-12-22T10:36:36Z
@@ -30123,16 +30373,15 @@
[Term]
id: GO:0003427
-name: regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division
+name: obsolete regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division
namespace: biological_process
-def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell that modulates the rate, frequency, or extent of the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell." [GOC:ascb_2009, GOC:dph, GOC:tb]
+def: "OBSOLETE. The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell that modulates the rate, frequency, or extent of the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division by planar cell polarity pathway" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb]
-is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity
-is_a: GO:0051493 ! regulation of cytoskeleton organization
-is_a: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0003426 ! cytoskeleton polarization involved in growth plate cartilage chondrocyte division
-relationship: regulates GO:0003426 ! cytoskeleton polarization involved in growth plate cartilage chondrocyte division
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003426
+consider: GO:0065007
created_by: dph
creation_date: 2009-12-22T11:43:29Z
@@ -30182,13 +30431,14 @@
[Term]
id: GO:0003432
-name: cell growth involved in growth plate cartilage chondrocyte morphogenesis
+name: obsolete cell growth involved in growth plate cartilage chondrocyte morphogenesis
namespace: biological_process
-def: "The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time." [GOC:ascb_2009, GOC:dph, GOC:tb]
-is_a: GO:0003430 ! growth plate cartilage chondrocyte growth
-intersection_of: GO:0048588 ! developmental cell growth
-intersection_of: part_of GO:0003429 ! growth plate cartilage chondrocyte morphogenesis
-relationship: part_of GO:0003429 ! growth plate cartilage chondrocyte morphogenesis
+def: "OBSOLETE. The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003429
+consider: GO:0048588
created_by: dph
creation_date: 2009-12-22T12:37:48Z
@@ -30234,25 +30484,27 @@
[Term]
id: GO:0003436
-name: regulation of cell adhesion involved in growth plate cartilage morphogenesis
+name: obsolete regulation of cell adhesion involved in growth plate cartilage morphogenesis
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone." [GOC:ascb_2009, GOC:dph, GOC:tb]
-is_a: GO:0030155 ! regulation of cell adhesion
-intersection_of: GO:0030155 ! regulation of cell adhesion
-intersection_of: part_of GO:0003422 ! growth plate cartilage morphogenesis
-relationship: part_of GO:0003422 ! growth plate cartilage morphogenesis
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003422
+consider: GO:0030155
created_by: dph
creation_date: 2009-12-22T01:28:15Z
[Term]
id: GO:0003437
-name: regulation of cell communication involved in growth plate cartilage morphogenesis
+name: obsolete regulation of cell communication involved in growth plate cartilage morphogenesis
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage." [GOC:ascb_2009, GOC:dph, GOC:tb]
-is_a: GO:0010646 ! regulation of cell communication
-intersection_of: GO:0010646 ! regulation of cell communication
-intersection_of: part_of GO:0003422 ! growth plate cartilage morphogenesis
-relationship: part_of GO:0003422 ! growth plate cartilage morphogenesis
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003422
+consider: GO:0010646
created_by: dph
creation_date: 2009-12-22T01:34:24Z
@@ -30339,6 +30591,7 @@
xref: Reactome:R-HSA-5693589 "D-loop dissociation and strand annealing"
is_a: GO:0004386 ! helicase activity
is_a: GO:0008094 ! ATP-dependent activity, acting on DNA
+property_value: skos:exactMatch EC:3.6.4.12
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23533" xsd:anyURI
[Term]
@@ -30447,6 +30700,7 @@
xref: Reactome:R-HSA-176264 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
is_a: GO:0008094 ! ATP-dependent activity, acting on DNA
relationship: has_part GO:0003677 ! DNA binding
+property_value: skos:broadMatch RHEA:13065
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -30622,7 +30876,6 @@
namespace: molecular_function
def: "A nuclear receptor activity regulated by steroid binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II." [GOC:signaling, PMID:14708019]
synonym: "steroid hormone receptor activity" BROAD []
-xref: Reactome:R-HSA-8963915 "1,25(OH)2D binds VDR"
is_a: GO:0004879 ! nuclear receptor activity
relationship: part_of GO:0030518 ! nuclear receptor-mediated steroid hormone signaling pathway
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16717" xsd:anyURI
@@ -30665,7 +30918,6 @@
synonym: "transcription cofactor activity" EXACT []
synonym: "transcription coreceptor activity" EXACT []
synonym: "transcriptional co-regulator" EXACT []
-xref: Reactome:R-HSA-5340251 "NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2"
is_a: GO:0030674 ! protein-macromolecule adaptor activity
is_a: GO:0140110 ! transcription regulator activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/15536" xsd:anyURI
@@ -30711,7 +30963,6 @@
synonym: "RNA polymerase II transcription co-repressor activity" RELATED []
synonym: "RNA polymerase II transcription corepressor activity" RELATED []
synonym: "transcription co-repressor activity" EXACT []
-xref: Reactome:R-HSA-400183 "PPARA:RXRA binds Corepressors of PPARA"
is_a: GO:0003712 ! transcription coregulator activity
relationship: part_of GO:0045892 ! negative regulation of DNA-templated transcription
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/15665" xsd:anyURI
@@ -30784,6 +31035,7 @@
xref: Reactome:R-HSA-163090 "Elongation Of The Telomeric Chromosome End"
xref: Reactome:R-HSA-164617 "Elongation of Extended Telomeric Chromosome End"
is_a: GO:0003964 ! RNA-directed DNA polymerase activity
+property_value: skos:broadMatch EC:2.7.7.49
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28394" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -30843,7 +31095,9 @@
is_a: GO:0004386 ! helicase activity
is_a: GO:0008186 ! ATP-dependent activity, acting on RNA
is_a: GO:0140098 ! catalytic activity, acting on RNA
+property_value: skos:exactMatch EC:3.6.4.13
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21612" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003725
@@ -30865,7 +31119,10 @@
xref: Reactome:R-HSA-77615 "Deamination at C6 position of adenosine in Editosome (ADAR2)"
xref: RHEA:10120
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.37
+property_value: skos:exactMatch RHEA:10120
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24880" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003727
@@ -31051,6 +31308,9 @@
xref: RHEA:16237
is_a: GO:0016859 ! cis-trans isomerase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:5.2.1.8
+property_value: skos:exactMatch RHEA:16237
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003756
@@ -31070,9 +31330,10 @@
xref: Reactome:R-HSA-8950113 "IL12A binds IL12B"
xref: Reactome:R-HSA-8950183 "IL12B binds IL23A"
xref: Reactome:R-HSA-8950456 "IL12B dimerizes"
-xref: Reactome:R-HSA-9760559 "DsbA catalyzes disulfide crosslink formation on STa"
is_a: GO:0016864 ! intramolecular oxidoreductase activity, transposing S-S bonds
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:5.3.4.1
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003759
@@ -31110,8 +31371,7 @@
synonym: "chaperonin" EXACT []
synonym: "chaperonin ATPase activity" EXACT []
is_obsolete: true
-replaced_by: GO:0016887
-consider: GO:0006457
+replaced_by: GO:0044183
[Term]
id: GO:0003767
@@ -31191,8 +31451,6 @@
synonym: "muscle motor activity" EXACT []
is_obsolete: true
replaced_by: GO:0000146
-consider: GO:0006936
-consider: GO:0043292
[Term]
id: GO:0003777
@@ -31216,6 +31474,7 @@
is_a: GO:0140657 ! ATP-dependent activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18664" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29690" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
created_by: vw
creation_date: 2016-04-04T10:59:42Z
@@ -31419,6 +31678,8 @@
xref: Reactome:R-HSA-8862320 "LYZ hydrolyzes peptidoglycans in the bacterial cell wall"
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
is_a: GO:0061783 ! peptidoglycan muralytic activity
+property_value: skos:exactMatch EC:3.2.1.17
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003797
@@ -31650,6 +31911,9 @@
xref: RHEA:54816
is_a: GO:0016755 ! aminoacyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.3.2.13
+property_value: skos:exactMatch RHEA:54816
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003811
@@ -31872,6 +32136,9 @@
xref: MetaCyc:TREHALOSE6PSYN-RXN
xref: RHEA:18889
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.15
+property_value: skos:exactMatch RHEA:18889
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003827
@@ -31896,6 +32163,9 @@
xref: RHEA:11456
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.101
+property_value: skos:exactMatch RHEA:11456
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003828
@@ -31915,6 +32185,9 @@
xref: Reactome:R-HSA-9845587 "ST8SIA5 transfers Neu5Ac to gangliosides"
xref: RHEA:19313
is_a: GO:0008373 ! sialyltransferase activity
+property_value: skos:exactMatch EC:2.4.3.8
+property_value: skos:exactMatch RHEA:19313
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003829
@@ -31932,10 +32205,12 @@
xref: EC:2.4.1.102
xref: MetaCyc:2.4.1.102-RXN
xref: Reactome:R-HSA-914012 "GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins"
-xref: Reactome:R-HSA-914018 "GCNT3 transfers GlcNAc to Core 3 mucin"
+xref: Reactome:R-HSA-914018 "Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein"
xref: RHEA:18705
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.102
+property_value: skos:exactMatch RHEA:18705
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21793" xsd:anyURI
[Term]
@@ -31957,6 +32232,9 @@
xref: RHEA:15509
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.144
+property_value: skos:exactMatch RHEA:15509
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003831
@@ -31989,6 +32267,9 @@
xref: Reactome:R-HSA-975919 "Addition of galactose by beta 4-galactosyltransferases"
xref: RHEA:22932
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.38
+property_value: skos:exactMatch RHEA:22932
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003832
@@ -31999,6 +32280,7 @@
synonym: "NBAD hydrolase activity" EXACT []
xref: RHEA:73467
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch RHEA:73467
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29728" xsd:anyURI
[Term]
@@ -32009,7 +32291,11 @@
synonym: "beta-alanyl-dopamine synthase activity" RELATED []
synonym: "N-beta-alanyl dopamine synthetase activity" EXACT []
synonym: "NBAD transferase activity" EXACT []
+xref: RHEA:73351
+xref: RHEA:73359
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:narrowMatch RHEA:73351
+property_value: skos:narrowMatch RHEA:73359
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20086" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30714" xsd:anyURI
@@ -32027,7 +32313,10 @@
xref: Reactome:R-HSA-975635 "BCMO1:Fe2+ cleaves betaC to atRAL"
xref: RHEA:32887
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.63
+property_value: skos:exactMatch RHEA:32887
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21765" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003835
@@ -32045,6 +32334,9 @@
xref: Reactome:R-HSA-977071 "ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens"
xref: RHEA:52104
is_a: GO:0008373 ! sialyltransferase activity
+property_value: skos:exactMatch EC:2.4.3.1
+property_value: skos:exactMatch RHEA:52104
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003836
@@ -32055,15 +32347,19 @@
xref: MetaCyc:2.4.99.4-RXN
xref: Reactome:R-HSA-1022129 "ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans"
xref: Reactome:R-HSA-1912378 "Sialylation of Pre-NOTCH"
-xref: Reactome:R-HSA-2046285 "ST3GAL1-4,6 optionally cap keratan chain"
+xref: Reactome:R-HSA-2046285 "The keratan chain can be capped by N-acetylneuraminic acid"
xref: Reactome:R-HSA-3656258 "Defective ST3GAL3 does not transfer SA to keratan"
xref: Reactome:R-HSA-4084984 "ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link)"
xref: Reactome:R-HSA-9603987 "ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG"
xref: Reactome:R-HSA-9605600 "ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG"
+xref: Reactome:R-HSA-981497 "ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position"
xref: Reactome:R-HSA-9844860 "ST3GAL5 transfers NeuNAc to ceramides"
xref: Reactome:R-HSA-9845538 "ST3GAL2,3 transfer Neu5Ac to gangliosides"
xref: RHEA:21616
is_a: GO:0008373 ! sialyltransferase activity
+property_value: skos:exactMatch EC:2.4.3.4
+property_value: skos:exactMatch RHEA:21616
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003837
@@ -32077,6 +32373,9 @@
xref: Reactome:R-HSA-73620 "beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2"
xref: RHEA:11184
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.6
+property_value: skos:exactMatch RHEA:11184
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003838
@@ -32104,8 +32403,11 @@
xref: RHEA:21128
is_a: GO:0008169 ! C-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.41
+property_value: skos:exactMatch RHEA:21128
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20399" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25963" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003839
@@ -32119,8 +32421,12 @@
xref: EC:4.3.2.9
xref: MetaCyc:GAMMA-GLUTAMYLCYCLOTRANSFERASE-RXN
xref: Reactome:R-HSA-1247922 "GGCT transforms gGluCys to OPRO"
+xref: Reactome:R-HSA-6785928 "CHAC1,2 cleaves GSH to OPRO and CysGly"
xref: RHEA:20505
is_a: GO:0016842 ! amidine-lyase activity
+property_value: skos:exactMatch EC:4.3.2.9
+property_value: skos:exactMatch RHEA:20505
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003840
@@ -32162,6 +32468,9 @@
xref: RHEA:19709
is_a: GO:0016411 ! acylglycerol O-acyltransferase activity
is_a: GO:0042171 ! lysophosphatidic acid acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.51
+property_value: skos:exactMatch RHEA:19709
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003842
@@ -32178,11 +32487,12 @@
synonym: "pyrroline-5-carboxylic acid dehydrogenase activity" RELATED [EC:1.2.1.88]
xref: EC:1.2.1.88
xref: MetaCyc:RXN-14116
-xref: Reactome:R-HSA-6784402 "ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate"
+xref: Reactome:R-HSA-6784399 "ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate"
xref: Reactome:R-HSA-70679 "ALDH4A1 oxidises L-GluSS to Glu"
-xref: Reactome:R-HSA-9929439 "ALDH4A1 oxidizes 1PYR-3OH-5COOH"
xref: RHEA:30235
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.88
+property_value: skos:exactMatch RHEA:30235
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23277" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30034" xsd:anyURI
@@ -32215,6 +32525,9 @@
xref: MetaCyc:13-BETA-GLUCAN-SYNTHASE-RXN
xref: RHEA:21476
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.34
+property_value: skos:exactMatch RHEA:21476
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003844
@@ -32239,11 +32552,15 @@
synonym: "starch branching enzyme" RELATED [EC:2.4.1.18]
xref: EC:2.4.1.18
xref: MetaCyc:GLYCOGEN-BRANCH-RXN
+xref: MetaCyc:RXN-7669
xref: Reactome:R-HSA-3322005 "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a"
xref: Reactome:R-HSA-3322016 "GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a"
xref: Reactome:R-HSA-3322057 "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b"
xref: Reactome:R-HSA-3878762 "Defective GBE1 does not catalyze branch formation in growing glycogen chains (liver)"
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.18
+property_value: skos:exactMatch MetaCyc:GLYCOGEN-BRANCH-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-7669
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28286" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -32258,6 +32575,7 @@
synonym: "beta-hydroxysteroid dehydrogenase" BROAD []
synonym: "corticosteroid 11-reductase" RELATED []
synonym: "corticosteroid 11beta-dehydrogenase" RELATED []
+xref: Reactome:R-HSA-194023 "HSD11B2,HSD11B1 dimer oxidise CORT to COR"
xref: Wikipedia:11beta-hydroxysteroid_dehydrogenase
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21915" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28173" xsd:anyURI
@@ -32281,7 +32599,11 @@
xref: Reactome:R-HSA-5696448 "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG"
xref: Reactome:R-HSA-6800334 "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG"
xref: RHEA:16741
+xref: RHEA:32947
is_a: GO:0016411 ! acylglycerol O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.22
+property_value: skos:exactMatch RHEA:16741
+property_value: skos:narrowMatch RHEA:32947
[Term]
id: GO:0003847
@@ -32305,6 +32627,9 @@
xref: Reactome:R-HSA-8869206 "PAFAH2 hydrolyses PAF to lyso-PAF and acetate"
xref: RHEA:17777
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.47
+property_value: skos:exactMatch RHEA:17777
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003848
@@ -32327,6 +32652,9 @@
xref: MetaCyc:H2PTERIDINEPYROPHOSPHOKIN-RXN
xref: RHEA:11412
is_a: GO:0016778 ! diphosphotransferase activity
+property_value: skos:exactMatch EC:2.7.6.3
+property_value: skos:exactMatch RHEA:11412
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003849
@@ -32363,6 +32691,9 @@
xref: MetaCyc:DAHPSYN-RXN
xref: RHEA:14717
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.54
+property_value: skos:exactMatch RHEA:14717
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003850
@@ -32376,6 +32707,9 @@
xref: MetaCyc:3.1.3.68-RXN
xref: RHEA:22236
is_a: GO:0050308 ! sugar-phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.68
+property_value: skos:exactMatch RHEA:22236
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003851
@@ -32388,9 +32722,12 @@
xref: Reactome:R-HSA-6785933 "UGT8 transfers Gal from UDP-Gal to CERA"
xref: RHEA:13093
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.47
+property_value: skos:exactMatch RHEA:13093
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27679" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28173" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003852
@@ -32410,6 +32747,9 @@
xref: MetaCyc:2-ISOPROPYLMALATESYN-RXN
xref: RHEA:21524
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.13
+property_value: skos:exactMatch RHEA:21524
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003853
@@ -32426,10 +32766,18 @@
synonym: "isobutyryl-CoA:FAD oxidoreductase activity" NARROW []
xref: EC:1.3.8.5
xref: KEGG_REACTION:R03169
+xref: MetaCyc:2-METHYLACYL-COA-DEHYDROGENASE-RXN
+xref: RHEA:43780
+xref: RHEA:44180
is_a: GO:0016937 ! short-chain fatty acyl-CoA dehydrogenase activity
+property_value: skos:exactMatch EC:1.3.8.5
+property_value: skos:narrowMatch MetaCyc:2-METHYLACYL-COA-DEHYDROGENASE-RXN
+property_value: skos:narrowMatch RHEA:43780
+property_value: skos:narrowMatch RHEA:44180
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23472" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23497" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26437" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003854
@@ -32458,7 +32806,12 @@
xref: Reactome:R-HSA-193816 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one"
xref: Reactome:R-HSA-196350 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione"
xref: Reactome:R-HSA-196372 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol"
+xref: RHEA:24076
+xref: RHEA:43932
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.145
+property_value: skos:narrowMatch RHEA:24076
+property_value: skos:narrowMatch RHEA:43932
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
[Term]
@@ -32481,6 +32834,9 @@
xref: MetaCyc:3-DEHYDROQUINATE-DEHYDRATASE-RXN
xref: RHEA:21096
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.10
+property_value: skos:exactMatch RHEA:21096
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003856
@@ -32492,6 +32848,9 @@
xref: MetaCyc:3-DEHYDROQUINATE-SYNTHASE-RXN
xref: RHEA:21968
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.4
+property_value: skos:exactMatch RHEA:21968
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003857
@@ -32526,6 +32885,8 @@
xref: RHEA:22432
xref: UM-BBD_reactionID:r1063
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.35
+property_value: skos:exactMatch RHEA:22432
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30577" xsd:anyURI
[Term]
@@ -32542,6 +32903,9 @@
xref: Reactome:R-HSA-73920 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+"
xref: RHEA:20521
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.30
+property_value: skos:exactMatch RHEA:20521
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003859
@@ -32574,7 +32938,10 @@
xref: Reactome:R-HSA-9916727 "HIBCH mutants don't synthesize beta-hydroxyisobutyrate"
xref: RHEA:20888
is_a: GO:0141126 ! short-chain fatty acyl-CoA hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.4
+property_value: skos:exactMatch RHEA:20888
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26441" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003861
@@ -32591,6 +32958,9 @@
xref: MetaCyc:3-ISOPROPYLMALISOM-RXN
xref: RHEA:32287
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.33
+property_value: skos:exactMatch RHEA:32287
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003862
@@ -32609,6 +32979,8 @@
xref: MetaCyc:3-ISOPROPYLMALDEHYDROG-RXN
xref: RHEA:32271
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.85
+property_value: skos:exactMatch RHEA:32271
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29562" xsd:anyURI
[Term]
@@ -32643,7 +33015,13 @@
synonym: "dehydrogenase, branched chain alpha-keto acid activity" RELATED [EC:1.2.4.4]
xref: EC:1.2.4.4
xref: MetaCyc:1.2.4.4-RXN
+xref: RHEA:13457
is_a: GO:0016624 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
+property_value: skos:broadMatch EC:1.2.1.25
+property_value: skos:broadMatch MetaCyc:1.2.1.25-RXN
+property_value: skos:exactMatch EC:1.2.4.4
+property_value: skos:exactMatch MetaCyc:1.2.4.4-RXN
+property_value: skos:narrowMatch RHEA:13457
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21144" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29951" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30031" xsd:anyURI
@@ -32663,6 +33041,9 @@
xref: MetaCyc:3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN
xref: RHEA:11824
is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity
+property_value: skos:exactMatch EC:2.1.2.11
+property_value: skos:exactMatch RHEA:11824
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003865
@@ -32694,8 +33075,11 @@
xref: Reactome:R-HSA-9705714 "SRD5A3 dehydrogenates TEST to DHTEST"
xref: RHEA:13805
is_a: GO:0033765 ! steroid dehydrogenase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.99.5
+property_value: skos:exactMatch RHEA:13805
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26703" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003866
@@ -32711,6 +33095,9 @@
xref: MetaCyc:2.5.1.19-RXN
xref: RHEA:21256
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.19
+property_value: skos:exactMatch RHEA:21256
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003867
@@ -32734,6 +33121,7 @@
synonym: "gamma-aminobutyric acid transaminase activity" EXACT []
synonym: "gamma-aminobutyric transaminase activity" EXACT []
synonym: "glutamate-succinic semialdehyde transaminase activity" EXACT []
+xref: Reactome:R-HSA-916855 "PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28802" xsd:anyURI
is_obsolete: true
@@ -32760,6 +33148,9 @@
xref: RHEA:16189
xref: UM-BBD_reactionID:r0298
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.27
+property_value: skos:exactMatch RHEA:16189
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003870
@@ -32791,6 +33182,9 @@
xref: Reactome:R-HSA-189442 "ALAS condenses SUCC-CoA and Gly to form dALA"
xref: RHEA:12921
is_a: GO:0016749 ! N-succinyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.37
+property_value: skos:exactMatch RHEA:12921
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003871
@@ -32798,7 +33192,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate." [EC:2.1.1.14, RHEA:21196]
synonym: "5-methyltetrahydropteroyltri-L-glutamate:L-homocysteine S-methyltransferase activity" RELATED [EC:2.1.1.14]
-synonym: "cobalamin-independent methionine synthase activity" RELATED [EC:2.1.1.14]
+synonym: "cobalamin-independent methionine synthase activity" EXACT [EC:2.1.1.14]
synonym: "homocysteine methylase activity" RELATED [EC:2.1.1.14]
synonym: "MetE" RELATED [EC:2.1.1.14]
synonym: "methionine synthase (cobalamin-independent) activity" RELATED [EC:2.1.1.14]
@@ -32811,7 +33205,10 @@
xref: MetaCyc:HOMOCYSMET-RXN
xref: RHEA:21196
is_a: GO:0008172 ! S-methyltransferase activity
-is_a: GO:0042085 ! 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.14
+property_value: skos:exactMatch RHEA:21196
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30968" xsd:anyURI
[Term]
id: GO:0003872
@@ -32833,10 +33230,13 @@
synonym: "phosphohexokinase activity" BROAD [EC:2.7.1.11]
xref: EC:2.7.1.11
xref: MetaCyc:6PFRUCTPHOS-RXN
-xref: Reactome:R-HSA-70467 "PFK tetramer phosphorylates Fru(6)P"
+xref: Reactome:R-HSA-70467 "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP"
xref: RHEA:16109
is_a: GO:0008443 ! phosphofructokinase activity
relationship: part_of GO:0061615 ! glycolytic process through fructose-6-phosphate
+property_value: skos:exactMatch EC:2.7.1.11
+property_value: skos:exactMatch RHEA:16109
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003873
@@ -32852,9 +33252,12 @@
xref: EC:2.7.1.105
xref: KEGG_REACTION:R02732
xref: MetaCyc:6-PHOSPHOFRUCTO-2-KINASE-RXN
-xref: Reactome:R-HSA-71802 "PFKFKB dimer phosphorylates Fru(6)P"
+xref: Reactome:R-HSA-71802 "D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP"
xref: RHEA:15653
is_a: GO:0008443 ! phosphofructokinase activity
+property_value: skos:exactMatch EC:2.7.1.105
+property_value: skos:exactMatch RHEA:15653
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003874
@@ -32871,6 +33274,9 @@
xref: Reactome:R-HSA-1474184 "DHNTP is dephosphorylated by PTPS to PTHP"
xref: RHEA:22048
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.12
+property_value: skos:exactMatch RHEA:22048
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003875
@@ -32886,8 +33292,17 @@
synonym: "protein ADP-ribosylarginine hydrolase activity" RELATED [EC:3.2.2.19]
synonym: "protein-nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity" RELATED [EC:3.2.2.19]
xref: EC:3.2.2.19
+xref: MetaCyc:ADP-RIBOSYLARGININE-HYDROLASE-RXN
+xref: MetaCyc:RXN-8732
+xref: RHEA:14885
+xref: RHEA:20784
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:3.2.2.19
+property_value: skos:narrowMatch MetaCyc:ADP-RIBOSYLARGININE-HYDROLASE-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-8732
+property_value: skos:narrowMatch RHEA:14885
+property_value: skos:narrowMatch RHEA:20784
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -32916,6 +33331,9 @@
xref: Reactome:R-HSA-76590 "AMP + H2O => IMP + NH4+ (AMPD)"
xref: RHEA:14777
is_a: GO:0047623 ! adenosine-phosphate deaminase activity
+property_value: skos:exactMatch EC:3.5.4.6
+property_value: skos:exactMatch RHEA:14777
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003877
@@ -32936,7 +33354,10 @@
xref: MetaCyc:ATP-ADENYLYLTRANSFERASE-RXN
xref: RHEA:16577
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.53
+property_value: skos:exactMatch RHEA:16577
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27575" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003878
@@ -32964,6 +33385,11 @@
xref: Reactome:R-HSA-75848 "ACLY tetramer transforms CIT to Ac-CoA"
xref: RHEA:21160
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.8
+property_value: skos:exactMatch KEGG_REACTION:R00352
+property_value: skos:exactMatch MetaCyc:ATP-CITRATE-PRO-S--LYASE-RXN
+property_value: skos:exactMatch RHEA:21160
+property_value: skos:relatedMatch MetaCyc:PWY-5172
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -32985,6 +33411,9 @@
xref: MetaCyc:ATPPHOSPHORIBOSYLTRANS-RXN
xref: RHEA:18473
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.17
+property_value: skos:exactMatch RHEA:18473
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003880
@@ -33018,6 +33447,9 @@
xref: Reactome:R-HSA-1482976 "CDP-DAG is converted to PI by CDIPT"
xref: RHEA:11580
is_a: GO:0017169 ! CDP-alcohol phosphatidyltransferase activity
+property_value: skos:exactMatch EC:2.7.8.11
+property_value: skos:exactMatch RHEA:11580
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003882
@@ -33042,6 +33474,9 @@
xref: MetaCyc:PHOSPHASERSYN-RXN
xref: RHEA:16913
is_a: GO:0017169 ! CDP-alcohol phosphatidyltransferase activity
+property_value: skos:exactMatch EC:2.7.8.8
+property_value: skos:exactMatch RHEA:16913
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003883
@@ -33060,6 +33495,9 @@
xref: Reactome:R-HSA-73647 "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]"
xref: RHEA:26426
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.2
+property_value: skos:exactMatch RHEA:26426
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003884
@@ -33074,6 +33512,9 @@
xref: Reactome:R-HSA-389821 "glycine + O2 => glyoxylate + H2O2 + NH4+"
xref: RHEA:21816
is_a: GO:0008131 ! primary methylamine oxidase activity
+property_value: skos:exactMatch EC:1.4.3.3
+property_value: skos:exactMatch RHEA:21816
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003885
@@ -33086,6 +33527,9 @@
xref: MetaCyc:1.1.3.37-RXN
xref: RHEA:23756
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.37
+property_value: skos:exactMatch RHEA:23756
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003886
@@ -33117,6 +33561,9 @@
xref: RHEA:13681
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
is_a: GO:0009008 ! DNA-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.37
+property_value: skos:exactMatch MetaCyc:DNA-CYTOSINE-5--METHYLTRANSFERASE-RXN
+property_value: skos:exactMatch RHEA:13681
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28396" xsd:anyURI
[Term]
@@ -33204,10 +33651,10 @@
xref: Reactome:R-HSA-69116 "Formation of Okazaki fragments"
xref: Reactome:R-HSA-73932 "Resynthesis of excised residue by POLB"
xref: Reactome:R-HSA-9710480 "Decitabine triphosphate incorporates into DNA"
-xref: Reactome:R-HSA-9914364 "POLG in the replisome polymerizes the H strand"
-xref: Reactome:R-HSA-9914498 "POLG in the replisome polymerizes the L strand"
is_a: GO:0034061 ! DNA polymerase activity
+property_value: skos:exactMatch EC:2.7.7.7
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28442" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003892
@@ -33265,13 +33712,10 @@
xref: Reactome:R-HSA-167121 "Addition of the third nucleotide on the nascent HIV-1 transcript"
xref: Reactome:R-HSA-167136 "Addition of nucleotides 5 through 9 on the growing HIV-1 transcript"
xref: Reactome:R-HSA-174425 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere"
-xref: Reactome:R-HSA-1964482 "RNA polymerase III transcribes microbial dsDNA to dsRNA"
xref: Reactome:R-HSA-203901 "Pol II mediated transcription of microRNA genes"
xref: Reactome:R-HSA-427366 "Transcription of intergenic spacer of the rRNA gene"
xref: Reactome:R-HSA-5601926 "RNA polymerase II polymerizes primary piRNA transcript"
xref: Reactome:R-HSA-6781824 "Active RNA Pol II complex transcribes lesion-containing DNA template"
-xref: Reactome:R-HSA-6814549 "Pre-snRNA transcript initiation, Integrator binding, LEC binding"
-xref: Reactome:R-HSA-6814559 "Pre-snRNA is elongated and capped with 7-methylguanosine"
xref: Reactome:R-HSA-68913 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin"
xref: Reactome:R-HSA-74986 "Elongation of pre-rRNA transcript"
xref: Reactome:R-HSA-75850 "Addition of the third nucleotide on the nascent transcript"
@@ -33281,10 +33725,9 @@
xref: Reactome:R-HSA-9670149 "TERRA transcription"
xref: Reactome:R-HSA-9697084 "Defective RpoB in Mtb RNAP transcribes RNA polyanion"
xref: Reactome:R-HSA-9697085 "RNAP transcribes Mtb RNA polyanion"
-xref: Reactome:R-HSA-9914409 "POLRMT polymerizes RNA primer for mitochondrial L strand replication"
-xref: Reactome:R-HSA-9915448 "POLRMT polymerizes R-loop RNA"
is_a: GO:0034062 ! 5'-3' RNA polymerase activity
relationship: part_of GO:0032774 ! RNA biosynthetic process
+property_value: skos:exactMatch EC:2.7.7.6
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29681" xsd:anyURI
[Term]
@@ -33337,9 +33780,16 @@
synonym: "PhrB photolyase activity" RELATED [EC:4.1.99.3]
synonym: "PRE" RELATED [EC:4.1.99.3]
xref: EC:4.1.99.3
+xref: MetaCyc:RXN-19243
+xref: MetaCyc:RXN-19244
xref: RHEA:10672
is_a: GO:0003913 ! DNA photolyase activity
+property_value: skos:exactMatch EC:4.1.99.3
+property_value: skos:exactMatch RHEA:10672
+property_value: skos:narrowMatch MetaCyc:RXN-19243
+property_value: skos:narrowMatch MetaCyc:RXN-19244
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003905
@@ -33358,6 +33808,8 @@
xref: EC:3.2.2.21
xref: MetaCyc:3.2.2.21-RXN
is_a: GO:0019104 ! DNA N-glycosylase activity
+property_value: skos:exactMatch EC:3.2.2.21
+property_value: skos:exactMatch MetaCyc:3.2.2.21-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
[Term]
@@ -33400,7 +33852,10 @@
xref: RHEA:24000
is_a: GO:0008172 ! S-methyltransferase activity
is_a: GO:0008276 ! protein methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.63
+property_value: skos:exactMatch RHEA:24000
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26174" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003909
@@ -33446,8 +33901,9 @@
synonym: "sealase activity" RELATED [EC:6.5.1.1]
xref: EC:6.5.1.1
xref: MetaCyc:DNA-LIGASE-ATP-RXN
-xref: Reactome:R-HSA-9914903 "LIG3 (Ligase III) ligates nascent mitochondrial DNA strands"
is_a: GO:0003909 ! DNA ligase activity
+property_value: skos:exactMatch EC:6.5.1.1
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003911
@@ -33479,6 +33935,8 @@
xref: EC:6.5.1.2
xref: MetaCyc:DNA-LIGASE-NAD+-RXN
is_a: GO:0003909 ! DNA ligase activity
+property_value: skos:exactMatch EC:6.5.1.2
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003912
@@ -33499,7 +33957,9 @@
xref: EC:2.7.7.31
xref: MetaCyc:DNA-NUCLEOTIDYLEXOTRANSFERASE-RXN
is_a: GO:0034061 ! DNA polymerase activity
+property_value: skos:exactMatch EC:2.7.7.31
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28442" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003913
@@ -33518,6 +33978,8 @@
xref: EC:4.1.99.13
xref: MetaCyc:RXN-10771
is_a: GO:0003913 ! DNA photolyase activity
+property_value: skos:exactMatch EC:4.1.99.13
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003916
@@ -33549,9 +34011,10 @@
synonym: "untwisting enzyme activity" RELATED [EC:5.6.2.1]
xref: EC:5.6.2.1
xref: MetaCyc:5.99.1.2-RXN
-xref: Reactome:R-HSA-9914922 "TOP3A (Topoisomerase 3a) decatenates mitochondrial DNA"
is_a: GO:0003916 ! DNA topoisomerase activity
+property_value: skos:exactMatch EC:5.6.2.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/15575" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003918
@@ -33574,8 +34037,10 @@
xref: Wikipedia:Type_II_topoisomerase
is_a: GO:0003916 ! DNA topoisomerase activity
is_a: GO:0008094 ! ATP-dependent activity, acting on DNA
+property_value: skos:exactMatch EC:5.6.2.2
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/15575" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17661" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003919
@@ -33598,6 +34063,9 @@
xref: Reactome:R-HSA-196929 "FLAD1 phosphorylates FMN"
xref: RHEA:17237
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.2
+property_value: skos:exactMatch RHEA:17237
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003920
@@ -33619,6 +34087,9 @@
xref: Reactome:R-HSA-514604 "GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)"
xref: RHEA:17185
is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.7.1.7
+property_value: skos:exactMatch RHEA:17185
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003921
@@ -33629,6 +34100,8 @@
xref: RHEA:18301
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
relationship: part_of GO:0003922 ! GMP synthase (glutamine-hydrolyzing) activity
+property_value: skos:exactMatch RHEA:18301
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003922
@@ -33652,6 +34125,9 @@
xref: Wikipedia:GMP_synthase_(glutamine-hydrolysing)
is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor
relationship: part_of GO:0006177 ! GMP biosynthetic process
+property_value: skos:exactMatch EC:6.3.5.2
+property_value: skos:exactMatch RHEA:11680
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003923
@@ -33751,11 +34227,12 @@
xref: Reactome:R-HSA-9645598 "RRAGC,D hydrolyzes GTP"
xref: Reactome:R-HSA-9649736 "RAS intrinsic GTPase activity hydrolyzes GTP to GDP"
xref: Reactome:R-HSA-983422 "Disassembly of COPII coated vesicle"
-xref: Reactome:R-HSA-9954919 "ABCE1:ATP binds PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide and HBS1L-1:GDP is released"
xref: RHEA:19669
is_a: GO:0017111 ! ribonucleoside triphosphate phosphatase activity
+property_value: skos:exactMatch RHEA:19669
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19078" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26014" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2015-11-11T12:47:56Z
@@ -33775,10 +34252,15 @@
synonym: "small GTPase activity" NARROW []
synonym: "small monomeric G protein activity" NARROW []
synonym: "small monomeric GTPase activity" NARROW []
+xref: EC:3.6.5.1
+xref: EC:3.6.5.2
xref: Reactome:R-HSA-400027 "Gq alpha:G beta:G gamma dissociates to Gq alpha:GTP and G beta:G gamma"
+xref: Reactome:R-HSA-400037 "Gi,Go Heterotrimeric G-protein complex dissociates"
xref: Reactome:R-HSA-422320 "Heterotrimeric G(s) complex dissociates"
is_a: GO:0003924 ! GTPase activity
is_a: GO:0098772 ! molecular function regulator activity
+property_value: skos:narrowMatch EC:3.6.5.1
+property_value: skos:narrowMatch EC:3.6.5.2
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19082" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26014" xsd:anyURI
@@ -33791,8 +34273,6 @@
synonym: "ARF small monomeric GTPase activity" EXACT []
is_obsolete: true
replaced_by: GO:0003924
-consider: GO:0016191
-consider: GO:0016192
[Term]
id: GO:0003928
@@ -33803,8 +34283,6 @@
synonym: "RAB small monomeric GTPase activity" EXACT []
is_obsolete: true
replaced_by: GO:0003924
-consider: GO:0016191
-consider: GO:0016192
[Term]
id: GO:0003929
@@ -33815,7 +34293,6 @@
synonym: "RAN small monomeric GTPase activity" EXACT []
is_obsolete: true
replaced_by: GO:0003924
-consider: GO:0006606
[Term]
id: GO:0003930
@@ -33826,7 +34303,6 @@
synonym: "RAS small monomeric GTPase activity" EXACT []
is_obsolete: true
replaced_by: GO:0003924
-consider: GO:0001558
[Term]
id: GO:0003931
@@ -33837,7 +34313,6 @@
synonym: "Rho small monomeric GTPase activity" EXACT []
is_obsolete: true
replaced_by: GO:0003924
-consider: GO:0007010
[Term]
id: GO:0003932
@@ -33848,7 +34323,6 @@
synonym: "SAR small monomeric GTPase activity" EXACT []
is_obsolete: true
replaced_by: GO:0003924
-consider: GO:0046903
[Term]
id: GO:0003933
@@ -33874,7 +34348,10 @@
xref: Reactome:R-HSA-1474146 "GCH1 reduces GTP to dihydroneopterin triphosphate"
xref: RHEA:17473
is_a: GO:0003933 ! GTP cyclohydrolase activity
+property_value: skos:exactMatch EC:3.5.4.16
+property_value: skos:exactMatch RHEA:17473
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26710" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003935
@@ -33889,7 +34366,10 @@
xref: MetaCyc:GTP-CYCLOHYDRO-II-RXN
xref: RHEA:23704
is_a: GO:0003933 ! GTP cyclohydrolase activity
+property_value: skos:exactMatch EC:3.5.4.25
+property_value: skos:exactMatch RHEA:23704
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26710" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003936
@@ -33919,6 +34399,9 @@
xref: Reactome:R-HSA-73797 "FAICAR => IMP + H2O"
xref: RHEA:18445
is_a: GO:0019238 ! cyclohydrolase activity
+property_value: skos:exactMatch EC:3.5.4.10
+property_value: skos:exactMatch RHEA:18445
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003938
@@ -33939,6 +34422,9 @@
xref: Reactome:R-HSA-9748945 "IMPDH tetramers dehydrogenate 6TIMP to 6TXMP"
xref: RHEA:11708
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.205
+property_value: skos:exactMatch RHEA:11708
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003939
@@ -33957,7 +34443,12 @@
xref: EC:1.1.1.14
xref: MetaCyc:L-IDITOL-2-DEHYDROGENASE-RXN
xref: Reactome:R-HSA-5652195 "SORD oxidizes D-sorbitol to Fru"
+xref: RHEA:10160
+xref: RHEA:33031
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.14
+property_value: skos:narrowMatch RHEA:10160
+property_value: skos:narrowMatch RHEA:33031
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28432" xsd:anyURI
@@ -33970,14 +34461,16 @@
synonym: "glycosaminoglycan alpha-L-iduronohydrolase activity" RELATED [EC:3.2.1.76]
xref: EC:3.2.1.76
xref: MetaCyc:3.2.1.76-RXN
-xref: Reactome:R-HSA-1678716 "IDUA cleaves iduronate from HS chain"
-xref: Reactome:R-HSA-1793186 "IDUA hydrolyses the unsulfated alpha-L-iduronosidic link in DS"
+xref: Reactome:R-HSA-1678716 "IDUA hydrolyses Heparan sulfate chain(1)"
+xref: Reactome:R-HSA-1793186 "IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS"
xref: Reactome:R-HSA-2090037 "IDUA hydrolyses Heparan sulfate chain(6)"
xref: Reactome:R-HSA-2206299 "Defective IDUA does not hydrolyse Heparan sulfate chain(6)"
xref: Reactome:R-HSA-9036037 "Defective IDUA does not hydrolyse Heparan sulfate chain(1)"
xref: Reactome:R-HSA-9036041 "Defective IDUA does not hydrolyse the unsulfated alpha-L-iduronosidic link in DS"
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.76
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28907" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003941
@@ -33993,9 +34486,11 @@
synonym: "serine deaminase activity" BROAD [EC:4.3.1.17]
xref: EC:4.3.1.17
xref: MetaCyc:4.3.1.17-RXN
-xref: Reactome:R-HSA-9929460 "SDS dimers:PXLP convert L-Ser to PYR and NH4+"
xref: RHEA:19169
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.17
+property_value: skos:exactMatch RHEA:19169
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003942
@@ -34013,6 +34508,9 @@
xref: MetaCyc:N-ACETYLGLUTPREDUCT-RXN
xref: RHEA:21588
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.38
+property_value: skos:exactMatch RHEA:21588
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003943
@@ -34033,6 +34531,8 @@
xref: Reactome:R-HSA-9036065 "Defective ARSB does not hydrolyse DS"
xref: Wikipedia:Arylsulfatase_B
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.12
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003944
@@ -34049,6 +34549,9 @@
xref: MetaCyc:3.1.4.45-RXN
xref: RHEA:24372
is_a: GO:0015929 ! hexosaminidase activity
+property_value: skos:exactMatch EC:3.1.4.45
+property_value: skos:exactMatch RHEA:24372
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003945
@@ -34085,6 +34588,9 @@
xref: MetaCyc:N-ACETYLLACTOSAMINE-SYNTHASE-RXN
xref: RHEA:17745
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.90
+property_value: skos:exactMatch RHEA:17745
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003947
@@ -34110,6 +34616,9 @@
xref: Reactome:R-HSA-8856223 "B4GALNT1 dimer transfers GalNAc to gangliosides"
xref: RHEA:12588
is_a: GO:0008376 ! acetylgalactosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.92
+property_value: skos:exactMatch RHEA:12588
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003948
@@ -34132,6 +34641,9 @@
xref: MetaCyc:3.5.1.26-RXN
xref: RHEA:11544
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.26
+property_value: skos:exactMatch RHEA:11544
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003949
@@ -34149,6 +34661,9 @@
xref: MetaCyc:PRIBFAICARPISOM-RXN
xref: RHEA:15469
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.16
+property_value: skos:exactMatch RHEA:15469
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003950
@@ -34176,7 +34691,9 @@
xref: Reactome:R-HSA-9686061 "Nucleoprotein is ADP-ribosylated"
xref: Reactome:R-HSA-9729279 "Nucleoprotein is ADP-ribosylated"
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.30
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29560" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003951
@@ -34197,7 +34714,10 @@
xref: RHEA:18629
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.23
+property_value: skos:exactMatch RHEA:18629
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28752" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003952
@@ -34219,6 +34739,9 @@
xref: RHEA:24384
xref: Wikipedia:NAD+_synthase_(glutamine-hydrolysing)
is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor
+property_value: skos:exactMatch EC:6.3.5.1
+property_value: skos:exactMatch MetaCyc:NAD-SYNTH-GLN-RXN
+property_value: skos:exactMatch RHEA:24384
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29467" xsd:anyURI
[Term]
@@ -34238,7 +34761,10 @@
xref: EC:3.2.2.5
xref: MetaCyc:RXN-13859
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:broadMatch RHEA:16301
+property_value: skos:exactMatch EC:3.2.2.5
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26011" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003954
@@ -34266,6 +34792,8 @@
synonym: "type I dehydrogenase activity" RELATED []
xref: RHEA:11356
is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H
+property_value: skos:exactMatch RHEA:11356
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003955
@@ -34304,6 +34832,7 @@
xref: MetaCyc:NQOR-RXN
xref: UM-BBD_reactionID:r0227
is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.6.5.2
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20616" xsd:anyURI
[Term]
@@ -34330,7 +34859,12 @@
xref: Reactome:R-HSA-450971 "NNT dimer transfers proton from NADPH to NAD+"
xref: RHEA:11692
is_a: GO:0016652 ! oxidoreductase activity, acting on NAD(P)H as acceptor
+property_value: skos:broadMatch KEGG_REACTION:R00112
+property_value: skos:broadMatch MetaCyc:PYRNUTRANSHYDROGEN-RXN
+property_value: skos:exactMatch EC:1.6.1.1
+property_value: skos:exactMatch RHEA:11692
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27814" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003958
@@ -34374,6 +34908,9 @@
xref: Reactome:R-HSA-76494 "POR reduces CYP450:Fe3+ to CYP450:Fe2+"
xref: RHEA:24040
is_a: GO:0016653 ! oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
+property_value: skos:exactMatch EC:1.6.2.4
+property_value: skos:exactMatch RHEA:24040
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003959
@@ -34402,6 +34939,8 @@
xref: Reactome:R-HSA-9018901 "5-HEDH dehydrogenates 5(S)-Hp-18(R)-HEPE to 18(R)-RvE2"
xref: RHEA:13149
is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H
+property_value: skos:exactMatch EC:1.6.99.1
+property_value: skos:exactMatch RHEA:13149
[Term]
id: GO:0003960
@@ -34418,6 +34957,9 @@
xref: RHEA:14269
is_a: GO:0003959 ! NADPH dehydrogenase activity
is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.6.5.5
+property_value: skos:exactMatch RHEA:14269
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30386" xsd:anyURI
[Term]
@@ -34439,9 +34981,13 @@
synonym: "OAH sulfhydrylase activity" RELATED [EC:2.5.1.49]
xref: EC:2.5.1.49
xref: MetaCyc:O-ACETYLHOMOSERINE-THIOL-LYASE-RXN
+xref: RHEA:10048
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
relationship: part_of GO:0071266 ! 'de novo' L-methionine biosynthetic process
+property_value: skos:exactMatch EC:2.5.1.49
+property_value: skos:narrowMatch RHEA:10048
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28681" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003962
@@ -34468,6 +35014,9 @@
xref: MetaCyc:O-SUCCHOMOSERLYASE-RXN
xref: RHEA:20397
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.48
+property_value: skos:exactMatch MetaCyc:O-SUCCHOMOSERLYASE-RXN
+property_value: skos:exactMatch RHEA:20397
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28811" xsd:anyURI
[Term]
@@ -34484,6 +35033,9 @@
is_a: GO:0009975 ! cyclase activity
is_a: GO:0016886 ! ligase activity, forming phosphoric ester bonds
is_a: GO:0140098 ! catalytic activity, acting on RNA
+property_value: skos:exactMatch EC:6.5.1.4
+property_value: skos:exactMatch RHEA:23976
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003964
@@ -34507,8 +35059,10 @@
xref: Reactome:R-HSA-164520 "Minus strand DNA synthesis resumes"
is_a: GO:0034061 ! DNA polymerase activity
relationship: part_of GO:0006278 ! RNA-templated DNA biosynthetic process
+property_value: skos:exactMatch EC:2.7.7.49
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28394" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28442" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003966
@@ -34571,6 +35125,7 @@
xref: Reactome:R-HSA-9837511 "Abortive replication of hRSV A"
is_a: GO:0034062 ! 5'-3' RNA polymerase activity
relationship: part_of GO:0001172 ! RNA-templated transcription
+property_value: skos:exactMatch EC:2.7.7.48
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23750" xsd:anyURI
[Term]
@@ -34595,7 +35150,9 @@
xref: MetaCyc:RNA-LIGASE-ATP-RXN
xref: Reactome:R-HSA-5696816 "tRNA ligase complex ligates tRNA exons"
is_a: GO:0008452 ! RNA ligase activity
+property_value: skos:exactMatch EC:6.5.1.3
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27418" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003973
@@ -34616,11 +35173,16 @@
synonym: "medium-chain-(S)-2-hydroxy-acid oxidase activity" NARROW []
synonym: "very-long-chain-(S)-2-hydroxy-acid oxidase activity" NARROW []
xref: EC:1.1.3.15
+xref: MetaCyc:RXN-969
xref: MetaCyc:S-2-HYDROXY-ACID-OXIDASE-RXN
xref: Reactome:R-HSA-389842 "HAO1 tetramer oxidizes glycolate to glyoxylate"
xref: Reactome:R-HSA-6787811 "HAO2 tetramer oxidises 2OH-PALM"
xref: RHEA:16789
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.15
+property_value: skos:exactMatch MetaCyc:S-2-HYDROXY-ACID-OXIDASE-RXN
+property_value: skos:exactMatch RHEA:16789
+property_value: skos:narrowMatch MetaCyc:RXN-969
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21795" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -34640,7 +35202,11 @@
xref: MetaCyc:UDP-N-ACETYLGLUCOSAMINE-4-EPIMERASE-RXN
xref: RHEA:20517
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.7
+property_value: skos:exactMatch RHEA:20517
+property_value: skos:relatedMatch MetaCyc:PWY-5512
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003975
@@ -34665,6 +35231,9 @@
xref: Reactome:R-HSA-4549334 "Defective DPAGT1 does not transfer GlcNAc to DOLP"
xref: RHEA:13289
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.15
+property_value: skos:exactMatch RHEA:13289
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003976
@@ -34683,6 +35252,9 @@
xref: MetaCyc:2.7.8.17-RXN
xref: RHEA:13581
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.17
+property_value: skos:exactMatch RHEA:13581
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003977
@@ -34706,6 +35278,9 @@
xref: Reactome:R-HSA-446204 "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine"
xref: RHEA:13509
is_a: GO:0070569 ! uridylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.23
+property_value: skos:exactMatch RHEA:13509
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003978
@@ -34731,6 +35306,9 @@
xref: Reactome:R-HSA-70369 "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc"
xref: RHEA:22168
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.2
+property_value: skos:exactMatch RHEA:22168
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003979
@@ -34743,6 +35321,9 @@
xref: Reactome:R-HSA-173597 "UDP-glucose is oxidised to UDP-glucuronate"
xref: RHEA:23596
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.22
+property_value: skos:exactMatch RHEA:23596
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003980
@@ -34754,7 +35335,9 @@
xref: RHEA:61304
is_a: GO:0035251 ! UDP-glucosyltransferase activity
relationship: part_of GO:0097359 ! UDP-glucosylation
+property_value: skos:exactMatch RHEA:61304
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25719" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003983
@@ -34776,9 +35359,12 @@
xref: EC:2.7.7.9
xref: KEGG_REACTION:R00289
xref: MetaCyc:GLUC1PURIDYLTRANS-RXN
-xref: Reactome:R-HSA-70286 "UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose"
+xref: Reactome:R-HSA-70286 "UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose"
xref: RHEA:19889
is_a: GO:0051748 ! UTP-monosaccharide-1-phosphate uridylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.9
+property_value: skos:exactMatch RHEA:19889
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003984
@@ -34796,9 +35382,15 @@
synonym: "pyruvate:pyruvate acetaldehydetransferase (decarboxylating)" RELATED [EC:2.2.1.6]
xref: EC:2.2.1.6
xref: MetaCyc:ACETOLACTSYN-RXN
+xref: RHEA:25249
+xref: RHEA:27654
is_a: GO:0016744 ! transketolase or transaldolase activity
+property_value: skos:exactMatch EC:2.2.1.6
+property_value: skos:narrowMatch RHEA:25249
+property_value: skos:narrowMatch RHEA:27654
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28613" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28938" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003985
@@ -34809,7 +35401,7 @@
synonym: "acetyl coenzyme A thiolase activity" RELATED []
xref: EC:2.3.1.9
xref: MetaCyc:ACETYL-COA-ACETYLTRANSFER-RXN
-xref: Reactome:R-HSA-70844 "alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA"
+xref: Reactome:R-HSA-70844 "alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA"
xref: Reactome:R-HSA-73916 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA"
xref: Reactome:R-HSA-74181 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA"
xref: Reactome:R-HSA-8848215 "ACAT2 condenses 2 Ac-CoA to form ACA-CoA"
@@ -34818,6 +35410,9 @@
xref: UM-BBD_reactionID:r0201
is_a: GO:0003988 ! acetyl-CoA C-acyltransferase activity
is_a: GO:0016453 ! C-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.9
+property_value: skos:exactMatch RHEA:21036
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003986
@@ -34837,6 +35432,9 @@
xref: Reactome:R-HSA-390304 "acetyl-CoA + H2O => acetate + CoASH + H+"
xref: RHEA:20289
is_a: GO:0016289 ! acyl-CoA hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.1
+property_value: skos:exactMatch RHEA:20289
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003987
@@ -34867,6 +35465,9 @@
xref: RHEA:23176
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.1
+property_value: skos:exactMatch RHEA:23176
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003988
@@ -34894,6 +35495,9 @@
xref: RHEA:21564
xref: UM-BBD_reactionID:r1051
is_a: GO:0016408 ! C-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.16
+property_value: skos:exactMatch RHEA:21564
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003989
@@ -34909,6 +35513,9 @@
xref: Reactome:R-HSA-8876889 "Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA"
xref: RHEA:11308
is_a: GO:0016421 ! CoA carboxylase activity
+property_value: skos:exactMatch EC:6.4.1.2
+property_value: skos:exactMatch RHEA:11308
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003990
@@ -34928,6 +35535,9 @@
xref: Reactome:R-HSA-372519 "AcCho is hydrolyzed to Cho and acetate by ACHE"
xref: RHEA:17561
is_a: GO:0004104 ! cholinesterase activity
+property_value: skos:exactMatch EC:3.1.1.7
+property_value: skos:exactMatch RHEA:17561
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003991
@@ -34945,6 +35555,9 @@
xref: RHEA:14629
is_a: GO:0016301 ! kinase activity
is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor
+property_value: skos:exactMatch EC:2.7.2.8
+property_value: skos:exactMatch RHEA:14629
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003992
@@ -34970,6 +35583,9 @@
xref: MetaCyc:ACETYLORNTRANSAM-RXN
xref: RHEA:18049
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.11
+property_value: skos:exactMatch RHEA:18049
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003993
@@ -34990,6 +35606,9 @@
xref: MetaCyc:ACID-PHOSPHATASE-RXN
xref: Reactome:R-HSA-196950 "2xTRAP hydrolyzes FMN to RIB"
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:broadMatch RHEA:15017
+property_value: skos:exactMatch EC:3.1.3.2
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003994
@@ -35008,6 +35627,9 @@
xref: Reactome:R-HSA-70971 "ACO2 isomerizes citrate"
xref: RHEA:10336
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.3
+property_value: skos:exactMatch RHEA:10336
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003995
@@ -35036,6 +35658,8 @@
xref: Reactome:R-HSA-77345 "Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2"
xref: RHEA:44704
is_a: GO:0052890 ! oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
+property_value: skos:exactMatch MetaCyc:ACYLCOADEHYDROG-RXN
+property_value: skos:exactMatch RHEA:44704
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23497" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25801" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -35057,7 +35681,10 @@
xref: Reactome:R-HSA-390256 "ACOX1 oxidizes C26:0 CoA"
xref: RHEA:38959
is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.3.3.6
+property_value: skos:exactMatch RHEA:38959
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28733" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003998
@@ -35074,7 +35701,10 @@
xref: MetaCyc:ACYLPHOSPHATASE-RXN
xref: RHEA:14965
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.7
+property_value: skos:exactMatch RHEA:14965
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0003999
@@ -35097,6 +35727,8 @@
xref: Reactome:R-HSA-9734193 "Defective APRT does not convert adenine to AMP"
xref: RHEA:16609
is_a: GO:0106130 ! purine phosphoribosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.7
+property_value: skos:exactMatch RHEA:16609
[Term]
id: GO:0004000
@@ -35110,6 +35742,8 @@
xref: RHEA:24408
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:broadMatch EC:3.5.4.4
+property_value: skos:exactMatch RHEA:24408
[Term]
id: GO:0004001
@@ -35126,7 +35760,10 @@
xref: RHEA:20824
is_a: GO:0019206 ! nucleoside kinase activity
relationship: part_of GO:0006167 ! AMP biosynthetic process
+property_value: skos:exactMatch EC:2.7.1.20
+property_value: skos:exactMatch RHEA:20824
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27917" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004005
@@ -35179,7 +35816,10 @@
xref: Reactome:R-HSA-5579084 "Defective AHCY does not hydrolyse AdoHcy"
xref: RHEA:21708
is_a: GO:0046508 ! hydrolase activity, acting on carbon-sulfur bonds
+property_value: skos:exactMatch EC:3.13.2.1
+property_value: skos:exactMatch RHEA:21708
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24053" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004014
@@ -35197,6 +35837,9 @@
xref: Reactome:R-HSA-351222 "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2"
xref: RHEA:15981
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.50
+property_value: skos:exactMatch RHEA:15981
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004015
@@ -35222,6 +35865,9 @@
xref: MetaCyc:DAPASYN-RXN
xref: RHEA:16861
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.62
+property_value: skos:exactMatch RHEA:16861
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004016
@@ -35248,6 +35894,9 @@
xref: RHEA:15389
is_a: GO:0009975 ! cyclase activity
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
+property_value: skos:exactMatch EC:4.6.1.1
+property_value: skos:exactMatch RHEA:15389
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004017
@@ -35268,6 +35917,9 @@
xref: Reactome:R-HSA-74220 "(d)AMP + ATP <=> (d)ADP + ADP (AK1)"
xref: RHEA:12973
is_a: GO:0050145 ! nucleoside monophosphate kinase activity
+property_value: skos:exactMatch EC:2.7.4.3
+property_value: skos:exactMatch MetaCyc:ADENYL-KIN-RXN
+property_value: skos:exactMatch RHEA:12973
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27917" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29533" xsd:anyURI
@@ -35285,6 +35937,8 @@
xref: MetaCyc:AMPSYN-RXN
xref: RHEA:16853
is_a: GO:0016842 ! amidine-lyase activity
+property_value: skos:broadMatch EC:4.3.2.2
+property_value: skos:exactMatch RHEA:16853
[Term]
id: GO:0004019
@@ -35302,6 +35956,9 @@
xref: Reactome:R-HSA-111524 "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]"
xref: RHEA:15753
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.4
+property_value: skos:exactMatch RHEA:15753
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004020
@@ -35327,7 +35984,10 @@
xref: RHEA:24152
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.25
+property_value: skos:exactMatch RHEA:24152
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28907" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004021
@@ -35361,6 +36021,11 @@
xref: Reactome:R-HSA-70524 "PXLP-K314-GPT transaminates PYR to form L-Ala"
xref: RHEA:19453
is_a: GO:0047635 ! alanine-oxo-acid transaminase activity
+property_value: skos:exactMatch EC:2.6.1.2
+property_value: skos:exactMatch KEGG_REACTION:R00258
+property_value: skos:exactMatch MetaCyc:ALANINE-AMINOTRANSFERASE-RXN
+property_value: skos:exactMatch RHEA:19453
+property_value: skos:relatedMatch MetaCyc:ALANINE-SYN2-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -35382,9 +36047,18 @@
synonym: "primary alcohol dehydrogenase" BROAD [EC:1.1.1.1]
synonym: "yeast alcohol dehydrogenase" NARROW [EC:1.1.1.1]
xref: EC:1.1.1.1
+xref: MetaCyc:ALCOHOL-DEHYDROG-GENERIC-RXN
+xref: MetaCyc:RXN-12448
xref: Reactome:R-HSA-2162078 "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+"
xref: Reactome:R-HSA-71707 "ethanol + NAD+ => acetaldehyde + NADH + H+"
+xref: RHEA:10736
+xref: RHEA:10740
is_a: GO:0018455 ! alcohol dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.1.1.1
+property_value: skos:narrowMatch MetaCyc:ALCOHOL-DEHYDROG-GENERIC-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-12448
+property_value: skos:narrowMatch RHEA:10736
+property_value: skos:narrowMatch RHEA:10740
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28532" xsd:anyURI
[Term]
@@ -35436,6 +36110,9 @@
xref: RHEA:17229
is_a: GO:0016413 ! O-acetyltransferase activity
is_a: GO:0034318 ! alcohol O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.84
+property_value: skos:exactMatch RHEA:17229
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004027
@@ -35466,6 +36143,9 @@
xref: Reactome:R-HSA-176609 "cholesterol + PAPS => cholesterol sulfate + PAP"
xref: RHEA:22552
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.2
+property_value: skos:exactMatch RHEA:22552
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004028
@@ -35506,9 +36186,12 @@
xref: UM-BBD_reactionID:r0605
xref: Wikipedia:Aldehyde_dehydrogenase_(NAD+)
is_a: GO:0004030 ! aldehyde dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.2.1.3
+property_value: skos:exactMatch RHEA:16185
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28144" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29544" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004030
@@ -35523,6 +36206,7 @@
xref: Reactome:R-HSA-5696080 "ALDH3B1 oxidises HXAL to PALM"
xref: Reactome:R-HSA-6808464 "ALDH3B2 oxidises HXAL to PALM"
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.5
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29544" xsd:anyURI
@@ -35537,9 +36221,20 @@
synonym: "retinal oxidase activity" NARROW []
xref: EC:1.2.3.1
xref: MetaCyc:ALDEHYDE-OXIDASE-RXN
+xref: MetaCyc:RETINAL-OXIDASE-RXN
+xref: MetaCyc:RXN-8093
+xref: MetaCyc:RXN-8094
xref: Reactome:R-HSA-3204311 "AOX1 oxidises PXL to PDXate"
xref: RHEA:16829
+xref: RHEA:22520
is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.2.3.1
+property_value: skos:exactMatch MetaCyc:ALDEHYDE-OXIDASE-RXN
+property_value: skos:exactMatch RHEA:16829
+property_value: skos:narrowMatch MetaCyc:RETINAL-OXIDASE-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-8093
+property_value: skos:narrowMatch MetaCyc:RXN-8094
+property_value: skos:narrowMatch RHEA:22520
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22680" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -35555,9 +36250,12 @@
xref: KEGG_REACTION:R02820
xref: Reactome:R-HSA-196060 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol"
xref: Reactome:R-HSA-5652172 "AKR1B1 reduces Glc to D-sorbitol"
-xref: Reactome:R-HSA-9931850 "AKR1B1 reduces galactose to galactitol"
xref: RHEA:12789
is_a: GO:0008106 ! alcohol dehydrogenase (NADP+) activity
+property_value: skos:broadMatch EC:1.1.1.21
+property_value: skos:broadMatch MetaCyc:ALDEHYDE-REDUCTASE-RXN
+property_value: skos:exactMatch KEGG_REACTION:R02820
+property_value: skos:exactMatch RHEA:12789
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27881" xsd:anyURI
@@ -35572,6 +36270,26 @@
synonym: "aldo-keto reductase (NADP+) activity" EXACT []
synonym: "aldo-keto reductase activity" EXACT []
synonym: "NADPH-dependent aldo-keto reductase activity" EXACT [GOC:vw]
+xref: Reactome:R-HSA-192033 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one"
+xref: Reactome:R-HSA-192036 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol"
+xref: Reactome:R-HSA-192067 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one"
+xref: Reactome:R-HSA-192160 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol"
+xref: Reactome:R-HSA-193746 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one"
+xref: Reactome:R-HSA-193755 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one"
+xref: Reactome:R-HSA-193758 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol"
+xref: Reactome:R-HSA-193781 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol"
+xref: Reactome:R-HSA-193800 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol"
+xref: Reactome:R-HSA-193821 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one"
+xref: Reactome:R-HSA-193824 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one"
+xref: Reactome:R-HSA-193841 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol"
+xref: Reactome:R-HSA-198845 "CYB5A:heme reduces Asc.- to AscH-"
+xref: Reactome:R-HSA-2855252 "AKRs reduce RBP2:atRAL to RBP2:atROL"
+xref: Reactome:R-HSA-5423637 "AKR dimers reduce AFBDHO to AFBDOH"
+xref: Reactome:R-HSA-5692232 "AKR1A1 oxidises BaPtDHD to BaP-7,8-dione"
+xref: Reactome:R-HSA-9027531 "Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA"
+xref: Reactome:R-HSA-9027562 "Dehydrogenase dehydrogenates 17-HDHA to 17-oxo-DHA"
+xref: Reactome:R-HSA-9027598 "Dehydrogenase dehydrogenates 13(R)-HDPAn-3 to 13-oxo-DPAn-3"
+xref: Reactome:R-HSA-9027600 "Dehydrogenase dehydrogenates 17-HDPAn-3 to 17-oxo-DPAn-3"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28532" xsd:anyURI
is_obsolete: true
@@ -35586,10 +36304,18 @@
synonym: "mutarotase activity" RELATED [EC:5.1.3.3]
xref: EC:5.1.3.3
xref: MetaCyc:ALDOSE-1-EPIMERASE-RXN
-xref: Reactome:R-HSA-9931853 "GALM converts beta-D-GAL to alpha-D-GAL"
-xref: Reactome:R-HSA-9931926 "Defective GALM doesn't convert beta-D-GAL to alpha-D-GAL"
+xref: RHEA:10264
+xref: RHEA:28675
+xref: RHEA:63332
+xref: RHEA:63336
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.3
+property_value: skos:narrowMatch RHEA:10264
+property_value: skos:narrowMatch RHEA:28675
+property_value: skos:narrowMatch RHEA:63332
+property_value: skos:narrowMatch RHEA:63336
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004035
@@ -35607,6 +36333,9 @@
xref: MetaCyc:ALKAPHOSPHA-RXN
xref: Reactome:R-HSA-8878787 "ALPI dimer hydrolyses phosphate monoesters"
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:broadMatch RHEA:15017
+property_value: skos:exactMatch EC:3.1.3.1
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004037
@@ -35620,6 +36349,9 @@
xref: MetaCyc:ALLANTOICASE-RXN
xref: RHEA:11016
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.4
+property_value: skos:exactMatch RHEA:11016
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004038
@@ -35631,6 +36363,9 @@
xref: MetaCyc:ALLANTOINASE-RXN
xref: RHEA:17029
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.5
+property_value: skos:exactMatch RHEA:17029
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004039
@@ -35645,6 +36380,9 @@
xref: RHEA:19029
xref: UM-BBD_reactionID:r0848
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.54
+property_value: skos:exactMatch RHEA:19029
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004040
@@ -35665,6 +36403,8 @@
xref: UM-BBD_reactionID:r0375
xref: UM-BBD_reactionID:r1440
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.4
+property_value: skos:exactMatch RHEA:12020
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -35683,6 +36423,8 @@
xref: Reactome:R-HSA-70542 "glutamate + acetyl CoA => N-acetyl glutamate + CoA"
xref: RHEA:24292
is_a: GO:0140085 ! L-amino-acid N-acetyltransferase activity
+property_value: skos:broadMatch EC:2.3.1.1
+property_value: skos:exactMatch RHEA:24292
[Term]
id: GO:0004043
@@ -35704,7 +36446,12 @@
xref: EC:1.2.1.31
xref: MetaCyc:1.2.1.31-RXN
xref: Reactome:R-HSA-70941 "alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+"
+xref: RHEA:12304
+xref: RHEA:12308
is_a: GO:0004030 ! aldehyde dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.2.1.31
+property_value: skos:narrowMatch RHEA:12304
+property_value: skos:narrowMatch RHEA:12308
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30732" xsd:anyURI
[Term]
@@ -35731,6 +36478,9 @@
xref: Reactome:R-HSA-73815 "5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate"
xref: RHEA:14905
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.14
+property_value: skos:exactMatch RHEA:14905
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004045
@@ -35746,12 +36496,13 @@
synonym: "N-substituted aminoacyl transfer RNA hydrolase activity" RELATED [EC:3.1.1.29]
xref: EC:3.1.1.29
xref: MetaCyc:AMINOCYL-TRNA-HYDROLASE-RXN
-xref: Reactome:R-HSA-9937374 "MTRFR:MTRES1:39S ribosomal subunit:mRNA:peptidyl-tRNA:MALSU1:MIEF1:NDUFAB1 dissociates"
-xref: Reactome:R-HSA-9937719 "ICT1 hydrolyzes the peptidyl-tRNA bond of the nascent polypeptide"
xref: RHEA:54448
is_a: GO:0052689 ! carboxylic ester hydrolase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:3.1.1.29
+property_value: skos:exactMatch RHEA:54448
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29746" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004046
@@ -35779,6 +36530,9 @@
xref: Reactome:R-HSA-9753944 "ACY1:Zn2+ dimer deacetylates NAC to L-Cys"
xref: RHEA:15565
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.14
+property_value: skos:exactMatch RHEA:15565
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004047
@@ -35797,6 +36551,12 @@
xref: Reactome:R-HSA-5693977 "AMT transfers NH2CH2 from GCSH:SAMDLL to THF"
xref: RHEA:16945
is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity
+property_value: skos:broadMatch EC:1.4.1.27
+property_value: skos:broadMatch MetaCyc:GCVMULTI-RXN
+property_value: skos:broadMatch RHEA:27758
+property_value: skos:exactMatch EC:2.1.2.10
+property_value: skos:exactMatch MetaCyc:GCVT-RXN
+property_value: skos:exactMatch RHEA:16945
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23282" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30262" xsd:anyURI
@@ -35819,6 +36579,9 @@
xref: MetaCyc:PRTRANS-RXN
xref: RHEA:11768
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.18
+property_value: skos:exactMatch RHEA:11768
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004049
@@ -35831,6 +36594,9 @@
xref: MetaCyc:ANTHRANSYN-RXN
xref: RHEA:21732
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.27
+property_value: skos:exactMatch RHEA:21732
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004050
@@ -35841,8 +36607,11 @@
xref: MetaCyc:RXN-14024
xref: RHEA:36795
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.5
+property_value: skos:exactMatch RHEA:36795
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/2473" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004051
@@ -35864,8 +36633,18 @@
synonym: "leukotriene-A4 synthase activity" RELATED [EC:1.13.11.34]
synonym: "LTA synthase activity" NARROW [EC:1.13.11.34]
xref: EC:1.13.11.34
+xref: MetaCyc:ARACHIDONATE-5-LIPOXYGENASE-RXN
+xref: MetaCyc:RXN-8647
+xref: RHEA:17485
+xref: RHEA:17961
xref: RHEA:32307
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.34
+property_value: skos:exactMatch RHEA:32307
+property_value: skos:narrowMatch MetaCyc:ARACHIDONATE-5-LIPOXYGENASE-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-8647
+property_value: skos:narrowMatch RHEA:17485
+property_value: skos:narrowMatch RHEA:17961
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -35893,6 +36672,9 @@
xref: Reactome:R-HSA-9026007 "ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3"
xref: RHEA:10428
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.31
+property_value: skos:exactMatch RHEA:10428
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004053
@@ -35910,6 +36692,9 @@
xref: Reactome:R-HSA-70569 "arginine + H2O => ornithine + urea [ARG1]"
xref: RHEA:20569
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.1
+property_value: skos:exactMatch RHEA:20569
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004054
@@ -35926,6 +36711,9 @@
xref: RHEA:22940
is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor
is_a: GO:0019202 ! amino acid kinase activity
+property_value: skos:exactMatch EC:2.7.3.3
+property_value: skos:exactMatch RHEA:22940
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004055
@@ -35943,6 +36731,9 @@
xref: Reactome:R-HSA-70577 "ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA"
xref: RHEA:10932
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.5
+property_value: skos:exactMatch RHEA:10932
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004056
@@ -35961,6 +36752,9 @@
xref: Reactome:R-HSA-70573 "argininosuccinate <=> fumarate + arginine"
xref: RHEA:24020
is_a: GO:0016842 ! amidine-lyase activity
+property_value: skos:exactMatch EC:4.3.2.1
+property_value: skos:exactMatch RHEA:24020
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004057
@@ -35977,8 +36771,11 @@
is_a: GO:0016755 ! aminoacyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.3.2.8
+property_value: skos:exactMatch RHEA:10208
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30124" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004058
@@ -35999,12 +36796,14 @@
xref: Reactome:R-HSA-209859 "Decarboxylation of 5-hydroxytryptophan forms serotonin"
xref: Reactome:R-HSA-209924 "Dopa is decarboxylated to dopamine"
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.28
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004059
name: aralkylamine N-acetyltransferase activity
namespace: molecular_function
-def: "Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine." [EC:2.3.1.87]
+def: "Catalysis of the reaction: a 2-arylethylamine + acetyl-CoA = an N-acetyl-2-arylethylamine + CoA + H+." [RHEA:20497]
synonym: "AANAT activity" RELATED [EC:2.3.1.87]
synonym: "acetyl-CoA:2-arylethylamine N-acetyltransferase activity" RELATED [EC:2.3.1.87]
synonym: "arylalkylamine N-acetyltransferase activity" RELATED [EC:2.3.1.87]
@@ -36017,6 +36816,10 @@
xref: Reactome:R-HSA-209792 "N-acetylation of serotonin"
xref: RHEA:20497
is_a: GO:0008080 ! N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.87
+property_value: skos:exactMatch RHEA:20497
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31077" xsd:anyURI
[Term]
id: GO:0004060
@@ -36041,6 +36844,9 @@
xref: UM-BBD_reactionID:r1333
xref: UM-BBD_reactionID:r1626
is_a: GO:0008080 ! N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.5
+property_value: skos:exactMatch RHEA:16613
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004061
@@ -36059,6 +36865,9 @@
xref: Reactome:R-HSA-71189 "AFMID hydrolyses NFK to L-KYN"
xref: RHEA:13009
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.9
+property_value: skos:exactMatch RHEA:13009
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004062
@@ -36090,6 +36899,9 @@
xref: Reactome:R-HSA-176646 "p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP"
xref: RHEA:12164
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.1
+property_value: skos:exactMatch RHEA:12164
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004063
@@ -36117,6 +36929,9 @@
xref: UM-BBD_enzymeID:r0067
xref: UM-BBD_reactionID:r0064
is_a: GO:0016795 ! phosphoric triester hydrolase activity
+property_value: skos:exactMatch EC:3.1.8.1
+property_value: skos:exactMatch RHEA:18053
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004064
@@ -36132,6 +36947,9 @@
xref: RHEA:17309
xref: UM-BBD_reactionID:r0757
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.2
+property_value: skos:exactMatch RHEA:17309
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004065
@@ -36154,6 +36972,9 @@
xref: MetaCyc:ARYLSULFAT-RXN
xref: RHEA:17261
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.1
+property_value: skos:exactMatch RHEA:17261
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004066
@@ -36173,6 +36994,9 @@
xref: Reactome:R-HSA-70599 "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]"
xref: RHEA:12228
is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor
+property_value: skos:exactMatch EC:6.3.5.4
+property_value: skos:exactMatch RHEA:12228
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004067
@@ -36191,9 +37015,13 @@
xref: Reactome:R-HSA-6797627 "ASPG hydrolyses L-Asn to L-Asp"
xref: RHEA:21016
is_a: GO:0004040 ! amidase activity
+property_value: skos:broadMatch MetaCyc:ASPARAGHYD-RXN
+property_value: skos:exactMatch EC:3.5.1.1
+property_value: skos:exactMatch RHEA:21016
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30003" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004068
@@ -36210,6 +37038,10 @@
xref: MetaCyc:ASPDECARBOX-RXN
xref: RHEA:19497
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.11
+property_value: skos:exactMatch MetaCyc:ASPDECARBOX-RXN
+property_value: skos:exactMatch RHEA:19497
+property_value: skos:relatedMatch MetaCyc:PWY-5155
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -36252,11 +37084,16 @@
xref: MetaCyc:ASPAMINOTRANS-RXN
xref: Reactome:R-HSA-70581 "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]"
xref: Reactome:R-HSA-70592 "PXLP-K259-GOT1 transaminates 2-OG and L-Asp"
-xref: Reactome:R-HSA-70596 "GOT2 dimer transaminates L-Asp"
+xref: Reactome:R-HSA-70596 "GOT2 dimer deaminates L-Asp"
xref: Reactome:R-HSA-70613 "GOT2 transaminates OA and L-Glu"
xref: RHEA:21824
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.1
+property_value: skos:exactMatch RHEA:21824
+property_value: skos:relatedMatch MetaCyc:ASPARTATE-DEG1-PWY
+property_value: skos:relatedMatch MetaCyc:ASPARTATESYN-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004070
@@ -36281,6 +37118,9 @@
xref: Reactome:R-HSA-73573 "CAD hexamer transforms CAP to N-carb-L-Asp"
xref: RHEA:20013
is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity
+property_value: skos:exactMatch EC:2.1.3.2
+property_value: skos:exactMatch RHEA:20013
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004071
@@ -36294,6 +37134,9 @@
xref: MetaCyc:ASNSYNA-RXN
xref: RHEA:11372
is_a: GO:0016211 ! ammonia ligase activity
+property_value: skos:exactMatch EC:6.3.1.1
+property_value: skos:exactMatch RHEA:11372
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004072
@@ -36310,6 +37153,9 @@
xref: RHEA:23776
is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor
is_a: GO:0019202 ! amino acid kinase activity
+property_value: skos:exactMatch EC:2.7.2.4
+property_value: skos:exactMatch RHEA:23776
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004073
@@ -36328,6 +37174,9 @@
xref: MetaCyc:ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN
xref: RHEA:24284
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.11
+property_value: skos:exactMatch RHEA:24284
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004074
@@ -36340,8 +37189,10 @@
xref: MetaCyc:BILIVERDIN-REDUCTASE-RXN
xref: Reactome:R-HSA-189384 "BLVRA:Zn2+, BLVRB reduce BV to BIL"
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.24
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004075
@@ -36354,6 +37205,9 @@
xref: MetaCyc:BIOTIN-CARBOXYL-RXN
xref: RHEA:13501
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.14
+property_value: skos:exactMatch RHEA:13501
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004076
@@ -36367,7 +37221,10 @@
xref: MetaCyc:2.8.1.6-RXN
xref: RHEA:22060
is_a: GO:0016783 ! sulfurtransferase activity
+property_value: skos:exactMatch EC:2.8.1.6
+property_value: skos:exactMatch RHEA:22060
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29748" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004077
@@ -36387,21 +37244,33 @@
synonym: "biotin:apo-acetyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)" RELATED [EC:6.3.4.15]
synonym: "biotin:apocarboxylase ligase activity" RELATED [EC:6.3.4.15]
synonym: "HCS" RELATED [EC:6.3.4.15]
+xref: EC:6.3.4.10
+xref: EC:6.3.4.11
xref: EC:6.3.4.15
+xref: EC:6.3.4.9
+xref: MetaCyc:6.3.4.10-RXN
+xref: MetaCyc:6.3.4.11-RXN
+xref: MetaCyc:6.3.4.9-RXN
xref: MetaCyc:BIOTINLIG-RXN
-xref: Reactome:R-HSA-2993447 "HLCS biotinylates 6x(PCCA:PCCB)"
-xref: Reactome:R-HSA-2993799 "HLCS biotinylates 6xMCCC1:6xMCCC2"
-xref: Reactome:R-HSA-2993802 "HLCS biotinylates PC:Mn2+"
-xref: Reactome:R-HSA-2993814 "HLCS biotinylates ACACA:Mn2+"
-xref: Reactome:R-HSA-3323184 "Defective HLCS does not biotinylate ACACA:Mn2+"
-xref: Reactome:R-HSA-4167511 "HLCS biotinylates ACACB"
-xref: Reactome:R-HSA-9035987 "Defective HLCS does not biotinylate 6xMCCC1:6xMCCC2"
-xref: Reactome:R-HSA-9035988 "Defective HLCS does not biotinylate PC:Mn2+"
-xref: Reactome:R-HSA-9035990 "Defective HLCS does not biotinylate 6x(PCCA:PCCB)"
+xref: RHEA:11204
xref: RHEA:11756
+xref: RHEA:23668
+xref: RHEA:24376
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:6.3.4.15
+property_value: skos:exactMatch RHEA:11756
+property_value: skos:narrowMatch EC:6.3.4.10
+property_value: skos:narrowMatch EC:6.3.4.11
+property_value: skos:narrowMatch EC:6.3.4.9
+property_value: skos:narrowMatch MetaCyc:6.3.4.10-RXN
+property_value: skos:narrowMatch MetaCyc:6.3.4.11-RXN
+property_value: skos:narrowMatch MetaCyc:6.3.4.9-RXN
+property_value: skos:narrowMatch RHEA:11204
+property_value: skos:narrowMatch RHEA:23668
+property_value: skos:narrowMatch RHEA:24376
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28107" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004078
@@ -36460,6 +37329,9 @@
xref: Reactome:R-HSA-5696197 "NUDT2 hydrolyses GP4G to GTP, GMP"
xref: RHEA:22484
is_a: GO:0008796 ! bis(5'-nucleosyl)-tetraphosphatase activity
+property_value: skos:exactMatch EC:3.6.1.17
+property_value: skos:exactMatch RHEA:22484
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004082
@@ -36486,6 +37358,9 @@
xref: Reactome:R-HSA-6798335 "BPGM dimer isomerises 1,3BPG to 2,3BPG"
xref: RHEA:17765
is_a: GO:0016868 ! intramolecular phosphotransferase activity
+property_value: skos:exactMatch EC:5.4.2.4
+property_value: skos:exactMatch RHEA:17765
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004083
@@ -36514,6 +37389,7 @@
xref: Reactome:R-HSA-70723 "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]"
xref: Reactome:R-HSA-70724 "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2]"
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.42
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -36564,7 +37440,10 @@
xref: Reactome:R-HSA-70555 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]"
xref: RHEA:18029
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.16
+property_value: skos:exactMatch RHEA:18029
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24338" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004088
@@ -36589,6 +37468,8 @@
xref: Reactome:R-HSA-73577 "CAD hexamer transforms L-Gln to CAP"
xref: RHEA:18633
is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor
+property_value: skos:exactMatch EC:6.3.5.5
+property_value: skos:exactMatch RHEA:18633
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30008" xsd:anyURI
[Term]
@@ -36621,7 +37502,10 @@
xref: Reactome:R-HSA-1475436 "CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2"
xref: RHEA:10748
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.1
+property_value: skos:exactMatch RHEA:10748
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25985" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004090
@@ -36643,6 +37527,9 @@
xref: Reactome:R-HSA-8937419 "CBR3 reduces DOX to DOXOL"
xref: RHEA:19257
is_a: GO:0008106 ! alcohol dehydrogenase (NADP+) activity
+property_value: skos:exactMatch EC:1.1.1.184
+property_value: skos:exactMatch MetaCyc:CARBONYL-REDUCTASE-NADPH-RXN
+property_value: skos:exactMatch RHEA:19257
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28530" xsd:anyURI
[Term]
@@ -36670,6 +37557,9 @@
xref: RHEA:21136
is_a: GO:0016406 ! carnitine O-acyltransferase activity
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.7
+property_value: skos:exactMatch RHEA:21136
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004095
@@ -36699,6 +37589,9 @@
xref: RHEA:12661
is_a: GO:0016406 ! carnitine O-acyltransferase activity
is_a: GO:0016416 ! O-palmitoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.21
+property_value: skos:exactMatch RHEA:12661
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004096
@@ -36725,6 +37618,9 @@
xref: RHEA:20309
xref: UM-BBD_enzymeID:r1335
is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch EC:1.11.1.6
+property_value: skos:exactMatch RHEA:20309
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004097
@@ -36748,15 +37644,16 @@
synonym: "tyrosinase activity" BROAD [EC:1.10.3.1]
xref: EC:1.10.3.1
xref: MetaCyc:CATECHOL-OXIDASE-RXN
-xref: Reactome:R-HSA-5662662 "Tyrosinase oxidises tyrosine to dopaquinone"
-xref: Reactome:R-HSA-5662692 "Dopa is oxidized to dopaquinone by TYR"
-xref: Reactome:R-HSA-5663050 "DHI and DHICA polymerize forming eumelanin"
-xref: Reactome:R-HSA-8878581 "TYRP1 oxidises DHICA to IQCA"
+xref: MetaCyc:RXN-13061
xref: RHEA:21632
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.10.3.1
+property_value: skos:exactMatch RHEA:21632
+property_value: skos:narrowMatch MetaCyc:RXN-13061
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21024" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25794" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004098
@@ -36773,6 +37670,9 @@
xref: Reactome:R-HSA-9840949 "ARSA removes sulfate from SM3"
xref: RHEA:21300
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.8
+property_value: skos:exactMatch RHEA:21300
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004099
@@ -36785,6 +37685,9 @@
xref: RHEA:10464
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0019213 ! deacetylase activity
+property_value: skos:exactMatch EC:3.5.1.41
+property_value: skos:exactMatch RHEA:10464
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004100
@@ -36801,6 +37704,9 @@
xref: MetaCyc:CHITIN-SYNTHASE-RXN
xref: RHEA:16637
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.16
+property_value: skos:exactMatch RHEA:16637
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004102
@@ -36817,6 +37723,9 @@
xref: Reactome:R-HSA-264622 "Cho is acetylated to AcCho by CHAT"
xref: RHEA:18821
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.6
+property_value: skos:exactMatch RHEA:18821
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004103
@@ -36835,6 +37744,9 @@
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
relationship: part_of GO:0006657 ! CDP-choline pathway
+property_value: skos:exactMatch EC:2.7.1.32
+property_value: skos:exactMatch RHEA:12837
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004104
@@ -36857,6 +37769,9 @@
xref: MetaCyc:CHOLINESTERASE-RXN
xref: RHEA:21964
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.8
+property_value: skos:exactMatch RHEA:21964
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004105
@@ -36881,6 +37796,9 @@
xref: RHEA:18997
is_a: GO:0070567 ! cytidylyltransferase activity
relationship: part_of GO:0006657 ! CDP-choline pathway
+property_value: skos:exactMatch EC:2.7.7.15
+property_value: skos:exactMatch RHEA:18997
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004106
@@ -36894,6 +37812,9 @@
xref: MetaCyc:CHORISMATEMUT-RXN
xref: RHEA:13897
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.5
+property_value: skos:exactMatch RHEA:13897
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004107
@@ -36908,6 +37829,9 @@
xref: MetaCyc:CHORISMATE-SYNTHASE-RXN
xref: RHEA:21020
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.5
+property_value: skos:exactMatch RHEA:21020
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004108
@@ -36950,6 +37874,9 @@
xref: Reactome:R-HSA-189421 "CPO transforms COPRO3 to PPGEN9"
xref: RHEA:18257
is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.3.3.3
+property_value: skos:exactMatch RHEA:18257
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004110
@@ -36963,6 +37890,9 @@
xref: MetaCyc:CORTICOSTEROID-SIDE-CHAIN-ISOMERASE-RXN
xref: RHEA:17861
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.21
+property_value: skos:exactMatch RHEA:17861
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004111
@@ -36994,7 +37924,11 @@
xref: RHEA:17157
is_a: GO:0016301 ! kinase activity
is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor
+property_value: skos:exactMatch EC:2.7.3.2
+property_value: skos:exactMatch RHEA:17157
+property_value: skos:relatedMatch MetaCyc:PWY-6158
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004112
@@ -37024,6 +37958,9 @@
xref: MetaCyc:3.1.4.37-RXN
xref: RHEA:14489
is_a: GO:0004112 ! cyclic-nucleotide phosphodiesterase activity
+property_value: skos:exactMatch EC:3.1.4.37
+property_value: skos:exactMatch RHEA:14489
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004114
@@ -37052,6 +37989,9 @@
xref: Reactome:R-HSA-162425 "p-S295-PDE3B hydrolyses cAMP to AMP"
xref: RHEA:14653
is_a: GO:0004112 ! cyclic-nucleotide phosphodiesterase activity
+property_value: skos:exactMatch EC:3.1.4.17
+property_value: skos:exactMatch RHEA:14653
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004115
@@ -37075,6 +38015,9 @@
xref: Reactome:R-HSA-9865748 "PDE4D5 in p-S26-ANXA2:PP2A:PDE4D5:ITGA5:ITGB1:fibronectin hydrolyzes cAMP to yield AMP"
xref: RHEA:25277
is_a: GO:0004114 ! 3',5'-cyclic-nucleotide phosphodiesterase activity
+property_value: skos:exactMatch EC:3.1.4.53
+property_value: skos:exactMatch RHEA:25277
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004117
@@ -37086,6 +38029,7 @@
xref: Reactome:R-HSA-111955 "cAMP hydrolysis by Cam-PDE 1"
is_a: GO:0004115 ! 3',5'-cyclic-AMP phosphodiesterase activity
is_a: GO:0047555 ! 3',5'-cyclic-GMP phosphodiesterase activity
+property_value: skos:broadMatch EC:3.1.4.35
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22791" xsd:anyURI
[Term]
@@ -37095,6 +38039,7 @@
def: "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP." [GOC:mah, PMID:15210692, PMID:35216259]
comment: cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
is_a: GO:0004114 ! 3',5'-cyclic-nucleotide phosphodiesterase activity
+property_value: skos:broadMatch EC:3.1.4.17
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20117" xsd:anyURI
[Term]
@@ -37104,6 +38049,7 @@
def: "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP." [GOC:mah, PMID:35216259]
comment: cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
is_a: GO:0004114 ! 3',5'-cyclic-nucleotide phosphodiesterase activity
+property_value: skos:broadMatch EC:3.1.4.17
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20117" xsd:anyURI
[Term]
@@ -37142,6 +38088,9 @@
xref: Reactome:R-HSA-1614524 "PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine"
xref: RHEA:10112
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.22
+property_value: skos:exactMatch RHEA:10112
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004123
@@ -37160,7 +38109,10 @@
xref: Reactome:R-HSA-1614583 "PXLP-K212-CTH cleaves L-Cystathionine"
xref: RHEA:14005
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:broadMatch EC:4.4.1.1
+property_value: skos:exactMatch RHEA:14005
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004124
@@ -37184,7 +38136,10 @@
xref: MetaCyc:ACSERLY-RXN
xref: RHEA:14829
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
-relationship: part_of GO:0019344 ! cysteine biosynthetic process
+relationship: part_of GO:0019344 ! L-cysteine biosynthetic process
+property_value: skos:exactMatch EC:2.5.1.47
+property_value: skos:exactMatch RHEA:14829
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004125
@@ -37209,6 +38164,9 @@
xref: RHEA:22728
is_a: GO:0016785 ! selenotransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.9.1.1
+property_value: skos:exactMatch RHEA:22728
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004126
@@ -37220,12 +38178,22 @@
synonym: "cytosine nucleoside deaminase activity" RELATED [EC:3.5.4.5]
synonym: "deoxycytidine deaminase activity" RELATED []
xref: EC:3.5.4.5
+xref: MetaCyc:CYTIDEAM-RXN
+xref: MetaCyc:CYTIDEAM2-RXN
xref: Reactome:R-HSA-73608 "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)"
xref: Reactome:R-HSA-83677 "C4 deamination of cytidine"
xref: Reactome:R-HSA-9817513 "AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine"
+xref: RHEA:13433
+xref: RHEA:16069
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.5
+property_value: skos:narrowMatch MetaCyc:CYTIDEAM-RXN
+property_value: skos:narrowMatch MetaCyc:CYTIDEAM2-RXN
+property_value: skos:narrowMatch RHEA:13433
+property_value: skos:narrowMatch RHEA:16069
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004127
@@ -37276,6 +38244,8 @@
is_a: GO:0015453 ! oxidoreduction-driven active transmembrane transporter activity
is_a: GO:0022853 ! active monoatomic ion transmembrane transporter activity
relationship: has_part GO:0016675 ! oxidoreductase activity, acting on a heme group of donors
+property_value: skos:exactMatch EC:7.1.1.9
+property_value: skos:exactMatch RHEA:11436
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20924" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21275" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30272" xsd:anyURI
@@ -37298,6 +38268,9 @@
xref: MetaCyc:CYTOCHROME-C-PEROXIDASE-RXN
xref: RHEA:16581
is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch EC:1.11.1.5
+property_value: skos:exactMatch RHEA:16581
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004131
@@ -37311,6 +38284,9 @@
xref: RHEA:20605
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.1
+property_value: skos:exactMatch RHEA:20605
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004132
@@ -37330,6 +38306,9 @@
xref: RHEA:22924
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.12
+property_value: skos:exactMatch RHEA:22924
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004133
@@ -37357,8 +38336,15 @@
synonym: "disproportionating enzyme activity" RELATED [EC:2.4.1.25]
synonym: "oligo-1,4-1,4-glucantransferase activity" RELATED [EC:2.4.1.25]
xref: EC:2.4.1.25
+xref: MetaCyc:AMYLOMALT-RXN
+xref: MetaCyc:RXN-1828
+xref: MetaCyc:RXN-9023
xref: Reactome:R-HSA-71552 "limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin"
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.25
+property_value: skos:narrowMatch MetaCyc:AMYLOMALT-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-1828
+property_value: skos:narrowMatch MetaCyc:RXN-9023
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -37375,6 +38361,8 @@
xref: MetaCyc:3.2.1.33-RXN
xref: Reactome:R-HSA-71593 "((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose"
is_a: GO:0090599 ! alpha-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.33
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004136
@@ -37390,6 +38378,9 @@
xref: RHEA:23452
is_a: GO:0019136 ! deoxynucleoside kinase activity
relationship: part_of GO:0006170 ! dAMP biosynthetic process
+property_value: skos:exactMatch EC:2.7.1.76
+property_value: skos:exactMatch RHEA:23452
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004137
@@ -37406,6 +38397,9 @@
xref: MetaCyc:DEOXYCYTIDINE-KINASE-RXN
xref: RHEA:20061
is_a: GO:0019136 ! deoxynucleoside kinase activity
+property_value: skos:exactMatch EC:2.7.1.74
+property_value: skos:exactMatch RHEA:20061
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004138
@@ -37422,6 +38416,9 @@
xref: MetaCyc:DEOXYGUANOSINE-KINASE-RXN
xref: RHEA:19201
is_a: GO:0019136 ! deoxynucleoside kinase activity
+property_value: skos:exactMatch EC:2.7.1.113
+property_value: skos:exactMatch RHEA:19201
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004139
@@ -37440,6 +38437,9 @@
xref: Reactome:R-HSA-6787321 "DERA cleaves dR5P to GA3P and CH3CHO"
xref: RHEA:12821
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.4
+property_value: skos:exactMatch RHEA:12821
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004140
@@ -37458,6 +38458,9 @@
xref: RHEA:18245
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.24
+property_value: skos:exactMatch RHEA:18245
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004141
@@ -37472,6 +38475,9 @@
xref: MetaCyc:DETHIOBIOTIN-SYN-RXN
xref: RHEA:15805
is_a: GO:0016882 ! cyclo-ligase activity
+property_value: skos:exactMatch EC:6.3.3.3
+property_value: skos:exactMatch RHEA:15805
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004142
@@ -37500,6 +38506,9 @@
xref: RHEA:32939
is_a: GO:0017169 ! CDP-alcohol phosphatidyltransferase activity
relationship: part_of GO:0006657 ! CDP-choline pathway
+property_value: skos:exactMatch EC:2.7.8.2
+property_value: skos:exactMatch RHEA:32939
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004143
@@ -37516,7 +38525,10 @@
xref: RHEA:10272
is_a: GO:0001727 ! lipid kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.107
+property_value: skos:exactMatch RHEA:10272
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25280" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004144
@@ -37537,6 +38549,9 @@
xref: Reactome:R-HSA-8848580 "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG"
xref: RHEA:10868
is_a: GO:0016411 ! acylglycerol O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.20
+property_value: skos:exactMatch RHEA:10868
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004145
@@ -37563,6 +38578,8 @@
xref: Reactome:R-HSA-351208 "Spermidine => N-acetylated spermidine"
xref: RHEA:11116
is_a: GO:0008080 ! N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.57
+property_value: skos:exactMatch RHEA:11116
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30342" xsd:anyURI
[Term]
@@ -37588,6 +38605,9 @@
xref: Reactome:R-HSA-1497794 "Salvage - BH2 is reduced to BH4 by DHFR"
xref: RHEA:15009
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.3
+property_value: skos:exactMatch RHEA:15009
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004148
@@ -37627,6 +38647,20 @@
xref: Reactome:R-HSA-9907572 "Loss-of-function DLD mutants don't dehydrogenate dihydrolipoyl DBT"
xref: RHEA:15045
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:broadMatch EC:1.2.1.104
+property_value: skos:broadMatch EC:1.2.1.105
+property_value: skos:broadMatch EC:1.2.1.25
+property_value: skos:broadMatch EC:1.4.1.27
+property_value: skos:broadMatch KEGG_REACTION:R08549
+property_value: skos:broadMatch MetaCyc:1.2.1.25-RXN
+property_value: skos:broadMatch MetaCyc:2OXOGLUTARATEDEH-RXN
+property_value: skos:broadMatch MetaCyc:GCVMULTI-RXN
+property_value: skos:broadMatch RHEA:27758
+property_value: skos:broadMatch RHEA:27786
+property_value: skos:broadMatch RHEA:28042
+property_value: skos:exactMatch EC:1.8.1.4
+property_value: skos:exactMatch MetaCyc:1.8.1.4-RXN
+property_value: skos:exactMatch RHEA:15045
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24350" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29951" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30262" xsd:anyURI
@@ -37652,9 +38686,16 @@
synonym: "succinyl-CoA:enzyme-N6-(dihydrolipoyl)lysine S-succinyltransferase activity" RELATED [EC:2.3.1.61]
xref: EC:2.3.1.61
xref: Reactome:R-HSA-9853512 "DLST transfers succinyl to CoA"
+xref: Reactome:R-HSA-9858590 "DLST transfers glutaryl to CoA"
xref: RHEA:15213
is_a: GO:0016751 ! S-succinyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:broadMatch EC:1.2.1.105
+property_value: skos:broadMatch KEGG_REACTION:R08549
+property_value: skos:broadMatch MetaCyc:2OXOGLUTARATEDEH-RXN
+property_value: skos:broadMatch RHEA:27786
+property_value: skos:exactMatch EC:2.3.1.61
+property_value: skos:exactMatch RHEA:15213
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29951" xsd:anyURI
[Term]
@@ -37668,6 +38709,9 @@
xref: MetaCyc:H2NEOPTERINALDOL-RXN
xref: RHEA:10540
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.25
+property_value: skos:exactMatch RHEA:10540
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004151
@@ -37684,6 +38728,9 @@
xref: Reactome:R-HSA-73571 "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO"
xref: RHEA:24296
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.3
+property_value: skos:exactMatch RHEA:24296
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004152
@@ -37695,7 +38742,9 @@
xref: Reactome:R-HSA-73569 "DHODH:FMN oxidises (S)-DHO to orotate"
xref: RHEA:18073
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch RHEA:18073
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23786" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004153
@@ -37713,7 +38762,9 @@
name: dihydropterin oxidase activity
namespace: molecular_function
def: "Catalysis of the reaction: a 7,8-dihydropteridine compound + O2 = an oxidized 7,8-dihydropteridine compound + H2O2. Specific substrates and their fully oxidized products include: 7,8-dihydropteridin/pterin, 7,8-dihydrobiopterin/biopterin, 7,8-dihydroxanthopterin/xanthopterin and sepiapterin/oxidized sepiapterin." [GOC:sjm, PMID:1745247, PMID:38786926, PMID:6815189]
+xref: MetaCyc:RXN-15269
is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
+property_value: skos:narrowMatch MetaCyc:RXN-15269
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28340" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29654" xsd:anyURI
@@ -37738,7 +38789,13 @@
xref: EC:1.5.1.34
xref: MetaCyc:1.5.1.34-RXN
xref: Reactome:R-HSA-71130 "q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+"
+xref: RHEA:17865
+xref: RHEA:17869
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.34
+property_value: skos:exactMatch MetaCyc:1.5.1.34-RXN
+property_value: skos:narrowMatch RHEA:17865
+property_value: skos:narrowMatch RHEA:17869
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29460" xsd:anyURI
[Term]
@@ -37760,6 +38817,9 @@
xref: MetaCyc:H2PTEROATESYNTH-RXN
xref: RHEA:19949
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.15
+property_value: skos:exactMatch RHEA:19949
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004157
@@ -37778,6 +38838,9 @@
xref: Reactome:R-HSA-73618 "5,6-dihydrothymine + H2O => beta-ureidoisobutyrate"
xref: RHEA:16121
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.2
+property_value: skos:exactMatch RHEA:16121
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004158
@@ -37803,7 +38866,12 @@
synonym: "uracil reductase activity" NARROW []
xref: EC:1.3.1.1
xref: MetaCyc:DIHYDROURACIL-DEHYDROGENASE-NAD+-RXN
+xref: RHEA:20189
+xref: RHEA:28791
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.1
+property_value: skos:narrowMatch RHEA:20189
+property_value: skos:narrowMatch RHEA:28791
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21891" xsd:anyURI
[Term]
@@ -37822,7 +38890,11 @@
xref: EC:4.2.1.9
xref: MetaCyc:DIHYDROXYISOVALDEHYDRAT-RXN
xref: RHEA:24809
+xref: RHEA:27694
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.9
+property_value: skos:exactMatch RHEA:24809
+property_value: skos:narrowMatch RHEA:27694
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28613" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28938" xsd:anyURI
@@ -37848,6 +38920,8 @@
xref: Reactome:R-HSA-9717834 "GGPS1 hexamer transfers IPPP to DMAPP"
xref: RHEA:22408
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.1
+property_value: skos:exactMatch RHEA:22408
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28819" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
@@ -37884,6 +38958,9 @@
xref: Reactome:R-HSA-191414 "MVD decarboxylates MVA5PP to IPPP"
xref: RHEA:23732
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.33
+property_value: skos:exactMatch RHEA:23732
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004164
@@ -37899,8 +38976,11 @@
xref: RHEA:36415
is_a: GO:0008276 ! protein methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.98
+property_value: skos:exactMatch RHEA:36415
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25281" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25795" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004165
@@ -37921,11 +39001,24 @@
synonym: "dodecenoyl-CoA delta3-cis-delta2-trans-isomerase activity" NARROW [EC:5.3.3.8]
synonym: "dodecenoyl-CoA isomerase activity" RELATED [EC:5.3.3.8]
xref: EC:5.3.3.8
+xref: MetaCyc:ENOYL-COA-DELTA-ISOM-RXN
+xref: MetaCyc:RXN-7836
+xref: MetaCyc:RXN-7931
xref: Reactome:R-HSA-109338 "Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA"
xref: Reactome:R-HSA-6809808 "ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA"
+xref: RHEA:23716
+xref: RHEA:45228
xref: RHEA:45900
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.8
+property_value: skos:exactMatch RHEA:45900
+property_value: skos:narrowMatch MetaCyc:ENOYL-COA-DELTA-ISOM-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-7836
+property_value: skos:narrowMatch MetaCyc:RXN-7931
+property_value: skos:narrowMatch RHEA:23716
+property_value: skos:narrowMatch RHEA:45228
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21637" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004166
@@ -37944,6 +39037,9 @@
xref: MetaCyc:2.4.1.153-RXN
xref: RHEA:14693
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.153
+property_value: skos:exactMatch RHEA:14693
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004167
@@ -37975,9 +39071,11 @@
xref: EC:5.3.3.12
xref: KEGG_REACTION:R03673
xref: MetaCyc:DOPACHROME-DELTA-ISOMERASE-RXN
-xref: Reactome:R-HSA-5662660 "Dopachrome is transformed to DHICA by DCT"
xref: RHEA:13041
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.12
+property_value: skos:exactMatch RHEA:13041
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004168
@@ -37993,6 +39091,9 @@
xref: RHEA:13133
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.108
+property_value: skos:exactMatch RHEA:13133
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004169
@@ -38011,10 +39112,11 @@
xref: Reactome:R-HSA-5615556 "Defective POMT2 does not transfer Man from Dol-P-Man to DAG1"
xref: Reactome:R-HSA-5615604 "Defective POMT1 does not transfer Man from Dol-P-Man to DAG1"
xref: Reactome:R-HSA-5615637 "POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653)"
-xref: Reactome:R-HSA-9816277 "CDH1 is O-manosylated"
is_a: GO:0000030 ! mannosyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
relationship: part_of GO:0035269 ! protein O-linked glycosylation via mannose
+property_value: skos:exactMatch EC:2.4.1.109
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004170
@@ -38034,6 +39136,9 @@
xref: Reactome:R-HSA-73666 "dUTP + H2O => dUMP + pyrophosphate"
xref: RHEA:10248
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:exactMatch EC:3.6.1.23
+property_value: skos:exactMatch RHEA:10248
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004171
@@ -38070,6 +39175,9 @@
xref: MetaCyc:ECDYSONE-O-ACYLTRANSFERASE-RXN
xref: RHEA:15217
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.139
+property_value: skos:exactMatch RHEA:15217
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004174
@@ -38092,6 +39200,8 @@
is_a: GO:0009055 ! electron transfer activity
is_a: GO:0016649 ! oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor
relationship: part_of GO:0022904 ! respiratory electron transport chain
+property_value: skos:exactMatch EC:1.5.5.1
+property_value: skos:exactMatch RHEA:24052
[Term]
id: GO:0004175
@@ -38103,6 +39213,7 @@
synonym: "endoprotease activity" NARROW []
synonym: "proteasome endopeptidase activity" NARROW []
synonym: "proteinase" NARROW []
+xref: EC:3.4.99.-
xref: Reactome:R-HSA-1168640 "Ubiquitinated IkB is degraded"
xref: Reactome:R-HSA-1234159 "Proteasome proteolyzes ub-HIF-alpha"
xref: Reactome:R-HSA-1236935 "Proteasomal cleavage of substrate (26S proteasome catalyst)"
@@ -38128,7 +39239,7 @@
xref: Reactome:R-HSA-353125 "26S proteosome degrades ODC holoenzyme complex"
xref: Reactome:R-HSA-3640874 "Ub-RibC-AXIN is degraded by the proteasome"
xref: Reactome:R-HSA-3928656 "gamma-secretase cleaves EPHB2"
-xref: Reactome:R-HSA-450466 "AUF1:mRNA complex is degraded"
+xref: Reactome:R-HSA-450466 "AUF1:mRNA complex is destroyed"
xref: Reactome:R-HSA-4608855 "PRICKLE1 is degraded by the proteasome"
xref: Reactome:R-HSA-4641256 "Ubiquitinated AXIN is degraded by the proteasome"
xref: Reactome:R-HSA-4641260 "Ubiquitinated DVL1 is degraded by the proteasome"
@@ -38177,9 +39288,7 @@
xref: Reactome:R-HSA-9614271 "Autocleavage of ADGRG6"
xref: Reactome:R-HSA-9755303 "26S proteasome degrades HIFalpha"
xref: Reactome:R-HSA-9755306 "ub UBXN7 is degraded by the 26S proteasome"
-xref: Reactome:R-HSA-9760521 "Unknown peptidase cleaves pro-STa"
xref: Reactome:R-HSA-9762096 "Ub,pS335,S338,T NFE2L2 is degraded"
-xref: Reactome:R-HSA-9766223 "Proteasome-dependent degradation of ubiquitinated CDH1"
xref: Reactome:R-HSA-983150 "Proteasomal cleavage of substrate"
xref: Reactome:R-HSA-983158 "Trimming of peptides in ER"
xref: Reactome:R-HSA-9839376 "TGFBR3(784-851) degradation"
@@ -38188,19 +39297,8 @@
xref: Reactome:R-HSA-9908105 "Maturation of the 20S immunoproteasome core particle"
xref: Reactome:R-HSA-9908108 "Maturation of the 20S thymoproteasome core particle"
xref: Reactome:R-HSA-9908780 "Maturation of the preholospermatoproteasome"
-xref: Reactome:R-HSA-9912636 "Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst)"
-xref: Reactome:R-HSA-9912655 "Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst)"
-xref: Reactome:R-HSA-9912747 "Proteasomal clevage of exogenous antigen (immunoproteasome catalyst)"
-xref: Reactome:R-HSA-9912751 "Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst)"
-xref: Reactome:R-HSA-9929352 "Ubiquitinated CD274 is degraded by the 26S proteasome"
-xref: Reactome:R-HSA-9929486 "SPOP-mediated degradation of CD274 by 26S Proteosome"
-xref: Reactome:R-HSA-9931314 "Proteasomal degradation of polyUb-p-S195-CD274"
-xref: Reactome:R-HSA-9934884 "Proteolysis of K48polyUb,p-S-CRY1,2"
-xref: Reactome:R-HSA-9934887 "Proteolysis of K48polyUb-K107,p-S-CRY1,K48polyUb-K126,p-S-CRY2"
-xref: Reactome:R-HSA-9934893 "Proteolysis of K48polyUb-K,p-S-PER1,2,3"
-xref: Reactome:R-HSA-9949676 "The proteasome degrades the alanine-tailed K48-polyUb nascent peptide bound to LTN1:NEMF:TCF25:VCP hexamer"
-xref: Reactome:R-HSA-9954728 "The proteasome degrades the K48-polyubiquitinated alanine-tailed nascent peptide"
is_a: GO:0008233 ! peptidase activity
+property_value: skos:narrowMatch EC:3.4.99.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25813" xsd:anyURI
[Term]
@@ -38221,9 +39319,8 @@
xref: Reactome:R-HSA-9839751 "YME1L1 degrades mitochondrial intermembrane space proteins"
is_a: GO:0008233 ! peptidase activity
is_a: GO:0140657 ! ATP-dependent activity
-intersection_of: GO:0008233 ! peptidase activity
-intersection_of: has_part GO:0016887 ! ATP hydrolysis activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21612" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0004177
@@ -38231,12 +39328,33 @@
namespace: molecular_function
def: "Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain." [EC:3.4.11.-, https://www.ebi.ac.uk/merops/about/glossary.shtml#AMINOPEPTIDASE, PMID:24157837]
xref: EC:3.4.11.-
+xref: EC:3.4.11.1
+xref: EC:3.4.11.21
+xref: EC:3.4.11.22
+xref: EC:3.4.11.5
+xref: EC:3.4.11.6
+xref: EC:3.4.11.9
xref: https://www.ebi.ac.uk/merops/about/glossary.shtml#AMINOPEPTIDASE
+xref: MetaCyc:3.4.11.21-RXN
+xref: MetaCyc:3.4.11.5-RXN
+xref: MetaCyc:3.4.11.6-RXN
+xref: MetaCyc:3.4.11.9-RXN
xref: MetaCyc:RXN0-5052
xref: Reactome:R-HSA-1236954 "Trimming of peptides by IRAP in endocytic vesicles"
xref: Reactome:R-HSA-2534096 "METAP1/2 demethylates GNAT1"
xref: Reactome:R-HSA-983162 "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases"
is_a: GO:0008238 ! exopeptidase activity
+property_value: skos:exactMatch EC:3.4.11.-
+property_value: skos:narrowMatch EC:3.4.11.1
+property_value: skos:narrowMatch EC:3.4.11.21
+property_value: skos:narrowMatch EC:3.4.11.22
+property_value: skos:narrowMatch EC:3.4.11.5
+property_value: skos:narrowMatch EC:3.4.11.6
+property_value: skos:narrowMatch EC:3.4.11.9
+property_value: skos:narrowMatch MetaCyc:3.4.11.21-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.11.5-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.11.6-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.11.9-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19681" xsd:anyURI
[Term]
@@ -38266,11 +39384,17 @@
name: carboxypeptidase activity
namespace: molecular_function
def: "Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain." [https://www.ebi.ac.uk/merops/about/glossary.shtml#CARBOXYPEPTIDASE]
+xref: EC:3.4.17.11
+xref: MetaCyc:3.4.17.11-RXN
xref: Reactome:R-HSA-1247910 "CNDP2:2Mn2+ dimer hydrolyses CysGly"
xref: Reactome:R-HSA-9753632 "CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly"
xref: RHEA:28783
is_a: GO:0008238 ! exopeptidase activity
+property_value: skos:exactMatch RHEA:28783
+property_value: skos:narrowMatch EC:3.4.17.11
+property_value: skos:narrowMatch MetaCyc:3.4.17.11-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19681" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004181
@@ -38278,17 +39402,45 @@
namespace: molecular_function
def: "Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [https://www.ebi.ac.uk/merops/about/glossary.shtml#CARBOXYPEPTIDASE]
xref: EC:3.4.17.-
-xref: Reactome:R-HSA-2022378 "ACE2(18-805):Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-33) (Angiotensin-(1-9))"
-xref: Reactome:R-HSA-2022379 "ACE2(18-805):Zn2+ hydrolyzes AGT(25-32) (Angiotensin-(1-8)) to AGT(25-31) (Angiotensin-(1-7))"
-xref: Reactome:R-HSA-2028294 "Mast Cell Carboxypeptidase hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-33) (Angiotensin-(1-9))"
+xref: EC:3.4.17.1
+xref: EC:3.4.17.10
+xref: EC:3.4.17.16
+xref: EC:3.4.17.2
+xref: EC:3.4.17.21
+xref: EC:3.4.17.22
+xref: EC:3.4.17.3
+xref: EC:3.4.17.4
+xref: EC:3.4.17.6
+xref: MetaCyc:3.4.17.17-RXN
+xref: MetaCyc:ALANINE-CARBOXYPEPTIDASE-RXN
+xref: MetaCyc:CARBOXYPEPTIDASE-A-RXN
+xref: MetaCyc:GLY-X-CARBOXYPEPTIDASE-RXN
+xref: MetaCyc:LYSINEARGININE-CARBOXYPEPTIDASE-RXN
+xref: Reactome:R-HSA-2022378 "ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9)"
+xref: Reactome:R-HSA-2022379 "ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7)"
+xref: Reactome:R-HSA-2028294 "Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9)"
xref: Reactome:R-HSA-8852809 "CPN, CPB2 cleave C3a, C5a"
xref: Reactome:R-HSA-8866105 "CCPs deglutamylate tubulin"
xref: Reactome:R-HSA-8955712 "SVBP:VASH1,VASH2 hydrolyzes the terminal L-Tyr residue from alphaY-beta tubulin dimer"
xref: Reactome:R-HSA-9023159 "Carboxypeptidase E hydrolyzes Insulin(57-89) to yield C-peptide (Insulin(57-87))"
xref: Reactome:R-HSA-9023163 "Carboxypeptidase E cleaves Insulin(25-56) to yield Insulin(25-54)"
-xref: Reactome:R-HSA-9944488 "ACE2:Zn2+ cleaves 1-Ala-AGT(25-32) to yield Alamandine (1-Ala-AGT(25-31)"
is_a: GO:0004180 ! carboxypeptidase activity
is_a: GO:0008235 ! metalloexopeptidase activity
+property_value: skos:exactMatch EC:3.4.17.-
+property_value: skos:narrowMatch EC:3.4.17.1
+property_value: skos:narrowMatch EC:3.4.17.10
+property_value: skos:narrowMatch EC:3.4.17.16
+property_value: skos:narrowMatch EC:3.4.17.2
+property_value: skos:narrowMatch EC:3.4.17.21
+property_value: skos:narrowMatch EC:3.4.17.22
+property_value: skos:narrowMatch EC:3.4.17.3
+property_value: skos:narrowMatch EC:3.4.17.4
+property_value: skos:narrowMatch EC:3.4.17.6
+property_value: skos:narrowMatch MetaCyc:3.4.17.17-RXN
+property_value: skos:narrowMatch MetaCyc:ALANINE-CARBOXYPEPTIDASE-RXN
+property_value: skos:narrowMatch MetaCyc:CARBOXYPEPTIDASE-A-RXN
+property_value: skos:narrowMatch MetaCyc:GLY-X-CARBOXYPEPTIDASE-RXN
+property_value: skos:narrowMatch MetaCyc:LYSINEARGININE-CARBOXYPEPTIDASE-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19681" xsd:anyURI
[Term]
@@ -38355,10 +39507,22 @@
def: "Catalysis of the hydrolysis of a single C-terminal amino acid residue from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [https://www.ebi.ac.uk/merops/about/glossary.shtml#CARBOXYPEPTIDASE]
synonym: "serine carboxypeptidase activity" EXACT []
xref: EC:3.4.16.-
+xref: EC:3.4.16.2
+xref: EC:3.4.16.5
+xref: EC:3.4.16.6
+xref: MetaCyc:3.4.16.2-RXN
+xref: MetaCyc:3.4.16.5-RXN
xref: Reactome:R-HSA-158251 "prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer"
is_a: GO:0004180 ! carboxypeptidase activity
is_a: GO:0070008 ! serine-type exopeptidase activity
+property_value: skos:exactMatch EC:3.4.16.-
+property_value: skos:narrowMatch EC:3.4.16.2
+property_value: skos:narrowMatch EC:3.4.16.5
+property_value: skos:narrowMatch EC:3.4.16.6
+property_value: skos:narrowMatch MetaCyc:3.4.16.2-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.16.5-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19681" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004186
@@ -38450,11 +39614,33 @@
synonym: "aspartyl protease activity" NARROW []
synonym: "carboxyl protease activity" NARROW []
xref: EC:3.4.23.-
+xref: EC:3.4.23.1
+xref: EC:3.4.23.15
+xref: EC:3.4.23.20
+xref: EC:3.4.23.25
+xref: EC:3.4.23.32
+xref: EC:3.4.23.34
+xref: EC:3.4.23.35
+xref: EC:3.4.23.36
+xref: EC:3.4.23.4
+xref: EC:3.4.23.43
+xref: EC:3.4.23.49
+xref: EC:3.4.23.5
+xref: MetaCyc:3.4.23.1-RXN
+xref: MetaCyc:3.4.23.15-RXN
+xref: MetaCyc:3.4.23.20-RXN
+xref: MetaCyc:3.4.23.25-RXN
+xref: MetaCyc:3.4.23.32-RXN
+xref: MetaCyc:3.4.23.34-RXN
+xref: MetaCyc:3.4.23.35-RXN
+xref: MetaCyc:3.4.23.4-RXN
+xref: MetaCyc:3.4.23.43-RXN
+xref: MetaCyc:3.4.23.5-RXN
xref: Reactome:R-HSA-157353 "NEXT1 is cleaved to produce NICD1"
xref: Reactome:R-HSA-157640 "NEXT2 is cleaved to produce NICD2"
-xref: Reactome:R-HSA-2022403 "Renin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10))"
-xref: Reactome:R-HSA-2022412 "Renin hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10))"
-xref: Reactome:R-HSA-2065357 "Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-35) (Angiotensin-(1-10))"
+xref: Reactome:R-HSA-2022403 "Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10)"
+xref: Reactome:R-HSA-2022412 "Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10)"
+xref: Reactome:R-HSA-2065357 "Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10)"
xref: Reactome:R-HSA-2220988 "NEXT1 PEST domain mutants are cleaved to produce NICD1 PEST domain mutants"
xref: Reactome:R-HSA-373705 "Caspase cleavage of DCC"
xref: Reactome:R-HSA-9013361 "NEXT3 is cleaved to produce NICD3"
@@ -38462,7 +39648,31 @@
xref: Reactome:R-HSA-9604294 "Gamma-secretase cleaves NOTCH4"
is_a: GO:0004175 ! endopeptidase activity
is_a: GO:0070001 ! aspartic-type peptidase activity
+property_value: skos:exactMatch EC:3.4.23.-
+property_value: skos:narrowMatch EC:3.4.23.1
+property_value: skos:narrowMatch EC:3.4.23.15
+property_value: skos:narrowMatch EC:3.4.23.20
+property_value: skos:narrowMatch EC:3.4.23.25
+property_value: skos:narrowMatch EC:3.4.23.32
+property_value: skos:narrowMatch EC:3.4.23.34
+property_value: skos:narrowMatch EC:3.4.23.35
+property_value: skos:narrowMatch EC:3.4.23.36
+property_value: skos:narrowMatch EC:3.4.23.4
+property_value: skos:narrowMatch EC:3.4.23.43
+property_value: skos:narrowMatch EC:3.4.23.49
+property_value: skos:narrowMatch EC:3.4.23.5
+property_value: skos:narrowMatch MetaCyc:3.4.23.1-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.23.15-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.23.20-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.23.25-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.23.32-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.23.34-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.23.35-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.23.4-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.23.43-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.23.5-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20581" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004191
@@ -38566,6 +39776,26 @@
synonym: "metacaspase activity" NARROW [GOC:mtg_apoptosis]
synonym: "thiol endopeptidase activity" EXACT []
xref: EC:3.4.22.-
+xref: EC:3.4.22.1
+xref: EC:3.4.22.14
+xref: EC:3.4.22.15
+xref: EC:3.4.22.16
+xref: EC:3.4.22.27
+xref: EC:3.4.22.28
+xref: EC:3.4.22.34
+xref: EC:3.4.22.38
+xref: EC:3.4.22.40
+xref: EC:3.4.22.41
+xref: EC:3.4.22.8
+xref: MetaCyc:3.4.22.1-RXN
+xref: MetaCyc:3.4.22.14-RXN
+xref: MetaCyc:3.4.22.15-RXN
+xref: MetaCyc:3.4.22.16-RXN
+xref: MetaCyc:3.4.22.27-RXN
+xref: MetaCyc:3.4.22.34-RXN
+xref: MetaCyc:3.4.22.38-RXN
+xref: MetaCyc:3.4.22.40-RXN
+xref: MetaCyc:3.4.22.41-RXN
xref: Reactome:R-HSA-114252 "Cleavage of Procaspase-3 by the apoptosome"
xref: Reactome:R-HSA-114259 "Cleavage of Procaspase9 to caspase9"
xref: Reactome:R-HSA-114261 "Cleavage of Procaspase-7 by the apoptosome"
@@ -38609,7 +39839,7 @@
xref: Reactome:R-HSA-264865 "Caspase-mediated cleavage of Lamin A"
xref: Reactome:R-HSA-264871 "Caspase-mediated cleavage of Lamin B1"
xref: Reactome:R-HSA-3465448 "Caspase-8 and FLIP(L) processing at DISC"
-xref: Reactome:R-HSA-350158 "LGMN hydrolyzes GC, releasing CUBN and 25(OH)D"
+xref: Reactome:R-HSA-350158 "LGMN degrades GC"
xref: Reactome:R-HSA-350318 "Caspase-mediated cleavage of vimentin at TNLD (429)"
xref: Reactome:R-HSA-350319 "Caspase mediated cleavage of vimentin at IDVD (259)"
xref: Reactome:R-HSA-350651 "Caspase-mediated cleavage of MASK"
@@ -38631,7 +39861,6 @@
xref: Reactome:R-HSA-5660663 "Caspase-8 cleaves IL1B precursor"
xref: Reactome:R-HSA-5681987 "LC3 is cleaved by ATG4"
xref: Reactome:R-HSA-5682377 "LC3 de-lipidation by ATG4"
-xref: Reactome:R-HSA-6800797 "The PIDDosome activates CASP2"
xref: Reactome:R-HSA-6814387 "CASP14 cleaves filaggrin"
xref: Reactome:R-HSA-9012556 "IL37:2x(CASP1(120-197):CASP1(317-404)) cleaves IL37"
xref: Reactome:R-HSA-9013895 "Caspase-8 processing within TLR3 complex"
@@ -38658,22 +39887,34 @@
xref: Reactome:R-HSA-9694625 "nsp3 cleaves nsp1-4"
xref: Reactome:R-HSA-9694732 "3CLp cleaves pp1ab"
xref: Reactome:R-HSA-9697750 "RIPK1 is cleaved by CASP8:FLIP(L)"
+xref: Reactome:R-HSA-9710101 "CASP4, CASP5 cleave GSDMD"
xref: Reactome:R-HSA-9729704 "SARS-CoV-2 3CLpro dimer cleaves TAB1"
xref: Reactome:R-HSA-9729730 "SARS-CoV-2 nsp3 cleaves IRF3"
xref: Reactome:R-HSA-9729741 "SARS-CoV-2 3CLpro dimer cleaves NLRP12"
-xref: Reactome:R-HSA-9792568 "CTSL1 cleaves proHPSE"
-xref: Reactome:R-HSA-9947849 "CASP5 autocatalysis on LPS micelles"
-xref: Reactome:R-HSA-9947861 "CASP4 autocatalysis on LPS micelles"
-xref: Reactome:R-HSA-9947908 "CASP4 autocatalysis on the bacterial surface"
-xref: Reactome:R-HSA-9947978 "CASP5 cleaves IL18 at D36"
-xref: Reactome:R-HSA-9947987 "CASP4 cleaves IL18 at D36"
-xref: Reactome:R-HSA-9947997 "CASP5 cleaves GSDMD"
-xref: Reactome:R-HSA-9948146 "CASP4 cleaves GSDMD"
-xref: Reactome:R-HSA-9958657 "CASP4 cleaves IL1B at D27"
-xref: Reactome:R-HSA-9960522 "CASP5 cleaves IL1B at D27"
-xref: Reactome:R-HSA-9960526 "CASP4 cleaves IL1B at D116"
is_a: GO:0004175 ! endopeptidase activity
is_a: GO:0008234 ! cysteine-type peptidase activity
+property_value: skos:exactMatch EC:3.4.22.-
+property_value: skos:narrowMatch EC:3.4.22.1
+property_value: skos:narrowMatch EC:3.4.22.14
+property_value: skos:narrowMatch EC:3.4.22.15
+property_value: skos:narrowMatch EC:3.4.22.16
+property_value: skos:narrowMatch EC:3.4.22.27
+property_value: skos:narrowMatch EC:3.4.22.28
+property_value: skos:narrowMatch EC:3.4.22.34
+property_value: skos:narrowMatch EC:3.4.22.38
+property_value: skos:narrowMatch EC:3.4.22.40
+property_value: skos:narrowMatch EC:3.4.22.41
+property_value: skos:narrowMatch EC:3.4.22.8
+property_value: skos:narrowMatch MetaCyc:3.4.22.1-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.22.14-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.22.15-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.22.16-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.22.27-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.22.34-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.22.38-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.22.40-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.22.41-RXN
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004198
@@ -38681,11 +39922,17 @@
namespace: molecular_function
def: "Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium." [GOC:mah]
synonym: "calpain activity" NARROW []
+xref: EC:3.4.22.52
+xref: EC:3.4.22.53
+xref: EC:3.4.22.54
xref: Reactome:R-HSA-8848658 "CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins"
xref: Reactome:R-HSA-8863012 "Calpain cleaves p35 to p25"
xref: Reactome:R-HSA-9855106 "Calpain2 (m-Calpain) cleaves TLN1 (Talin-1)"
xref: Reactome:R-HSA-9861485 "Calpain2 (m-Calpain, CAPN2:CAPNS:Ca2+) cleaves VCL (Vinculin)"
is_a: GO:0004197 ! cysteine-type endopeptidase activity
+property_value: skos:narrowMatch EC:3.4.22.52
+property_value: skos:narrowMatch EC:3.4.22.53
+property_value: skos:narrowMatch EC:3.4.22.54
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29635" xsd:anyURI
[Term]
@@ -38698,7 +39945,6 @@
synonym: "signalling (initiator) caspase activity" EXACT []
is_obsolete: true
replaced_by: GO:0004197
-consider: GO:0006915
[Term]
id: GO:0004201
@@ -38770,7 +40016,6 @@
synonym: "effector caspase activity" EXACT []
is_obsolete: true
replaced_by: GO:0004197
-consider: GO:0006915
[Term]
id: GO:0004208
@@ -38932,6 +40177,52 @@
synonym: "metalloendoprotease activity" NARROW [GOC:mah]
synonym: "metalloendoproteinase activity" NARROW [GOC:mah]
xref: EC:3.4.24.-
+xref: EC:3.4.24.11
+xref: EC:3.4.24.14
+xref: EC:3.4.24.17
+xref: EC:3.4.24.18
+xref: EC:3.4.24.19
+xref: EC:3.4.24.21
+xref: EC:3.4.24.22
+xref: EC:3.4.24.23
+xref: EC:3.4.24.24
+xref: EC:3.4.24.3
+xref: EC:3.4.24.34
+xref: EC:3.4.24.35
+xref: EC:3.4.24.37
+xref: EC:3.4.24.55
+xref: EC:3.4.24.56
+xref: EC:3.4.24.57
+xref: EC:3.4.24.59
+xref: EC:3.4.24.61
+xref: EC:3.4.24.64
+xref: EC:3.4.24.65
+xref: EC:3.4.24.69
+xref: EC:3.4.24.7
+xref: EC:3.4.24.70
+xref: EC:3.4.24.71
+xref: EC:3.4.24.72
+xref: MetaCyc:3.4.24.11-RXN
+xref: MetaCyc:3.4.24.14-RXN
+xref: MetaCyc:3.4.24.17-RXN
+xref: MetaCyc:3.4.24.18-RXN
+xref: MetaCyc:3.4.24.19-RXN
+xref: MetaCyc:3.4.24.21-RXN
+xref: MetaCyc:3.4.24.22-RXN
+xref: MetaCyc:3.4.24.23-RXN
+xref: MetaCyc:3.4.24.24-RXN
+xref: MetaCyc:3.4.24.35-RXN
+xref: MetaCyc:3.4.24.37-RXN
+xref: MetaCyc:3.4.24.55-RXN
+xref: MetaCyc:3.4.24.56-RXN
+xref: MetaCyc:3.4.24.57-RXN
+xref: MetaCyc:3.4.24.59-RXN
+xref: MetaCyc:3.4.24.61-RXN
+xref: MetaCyc:3.4.24.64-RXN
+xref: MetaCyc:3.4.24.69-RXN
+xref: MetaCyc:3.4.24.70-RXN
+xref: MetaCyc:3.4.24.71-RXN
+xref: MetaCyc:3.4.24.72-RXN
xref: Reactome:R-HSA-1168777 "Metalloprotease cleavage of GHR"
xref: Reactome:R-HSA-1251992 "Cleavage of P-ERBB4jmA isoforms by ADAM17"
xref: Reactome:R-HSA-1299476 "MPP cleaves targeting peptide (presequence) of inner membrane precursors"
@@ -39034,7 +40325,55 @@
xref: Reactome:R-HSA-9844241 "ADAMTS13 cleaves VWF variant multimer"
is_a: GO:0004175 ! endopeptidase activity
is_a: GO:0008237 ! metallopeptidase activity
+property_value: skos:exactMatch EC:3.4.24.-
+property_value: skos:narrowMatch EC:3.4.24.11
+property_value: skos:narrowMatch EC:3.4.24.14
+property_value: skos:narrowMatch EC:3.4.24.17
+property_value: skos:narrowMatch EC:3.4.24.18
+property_value: skos:narrowMatch EC:3.4.24.19
+property_value: skos:narrowMatch EC:3.4.24.21
+property_value: skos:narrowMatch EC:3.4.24.22
+property_value: skos:narrowMatch EC:3.4.24.23
+property_value: skos:narrowMatch EC:3.4.24.24
+property_value: skos:narrowMatch EC:3.4.24.3
+property_value: skos:narrowMatch EC:3.4.24.34
+property_value: skos:narrowMatch EC:3.4.24.35
+property_value: skos:narrowMatch EC:3.4.24.37
+property_value: skos:narrowMatch EC:3.4.24.55
+property_value: skos:narrowMatch EC:3.4.24.56
+property_value: skos:narrowMatch EC:3.4.24.57
+property_value: skos:narrowMatch EC:3.4.24.59
+property_value: skos:narrowMatch EC:3.4.24.61
+property_value: skos:narrowMatch EC:3.4.24.64
+property_value: skos:narrowMatch EC:3.4.24.65
+property_value: skos:narrowMatch EC:3.4.24.69
+property_value: skos:narrowMatch EC:3.4.24.7
+property_value: skos:narrowMatch EC:3.4.24.70
+property_value: skos:narrowMatch EC:3.4.24.71
+property_value: skos:narrowMatch EC:3.4.24.72
+property_value: skos:narrowMatch MetaCyc:3.4.24.11-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.14-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.17-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.18-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.19-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.21-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.22-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.23-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.24-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.35-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.37-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.55-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.56-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.57-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.59-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.61-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.64-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.69-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.70-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.71-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.24.72-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28557" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004226
@@ -39113,7 +40452,9 @@
xref: EC:3.4.11.7
xref: MetaCyc:3.4.11.7-RXN
is_a: GO:0004177 ! aminopeptidase activity
+property_value: skos:exactMatch EC:3.4.11.7
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28557" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004231
@@ -39223,7 +40564,9 @@
xref: EC:3.4.11.18
xref: MetaCyc:3.4.11.18-RXN
is_a: GO:0004177 ! aminopeptidase activity
+property_value: skos:exactMatch EC:3.4.11.18
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22698" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004240
@@ -39409,12 +40752,54 @@
synonym: "blood coagulation factor activity" RELATED []
synonym: "serine elastase activity" RELATED [GOC:krc]
xref: EC:3.4.21.-
+xref: EC:3.4.21.1
+xref: EC:3.4.21.10
+xref: EC:3.4.21.102
+xref: EC:3.4.21.20
+xref: EC:3.4.21.21
+xref: EC:3.4.21.22
+xref: EC:3.4.21.26
+xref: EC:3.4.21.27
+xref: EC:3.4.21.34
+xref: EC:3.4.21.35
+xref: EC:3.4.21.36
+xref: EC:3.4.21.38
+xref: EC:3.4.21.39
+xref: EC:3.4.21.4
+xref: EC:3.4.21.41
+xref: EC:3.4.21.42
+xref: EC:3.4.21.43
+xref: EC:3.4.21.45
+xref: EC:3.4.21.46
+xref: EC:3.4.21.47
+xref: EC:3.4.21.48
+xref: EC:3.4.21.5
+xref: EC:3.4.21.53
+xref: EC:3.4.21.54
+xref: EC:3.4.21.59
+xref: EC:3.4.21.6
+xref: EC:3.4.21.61
+xref: EC:3.4.21.62
+xref: EC:3.4.21.68
+xref: EC:3.4.21.69
+xref: EC:3.4.21.7
+xref: EC:3.4.21.71
+xref: EC:3.4.21.73
+xref: EC:3.4.21.75
+xref: EC:3.4.21.78
+xref: EC:3.4.21.79
+xref: EC:3.4.21.83
+xref: EC:3.4.21.88
+xref: EC:3.4.21.9
+xref: EC:3.4.21.92
+xref: EC:3.4.21.93
+xref: EC:3.4.21.94
xref: Reactome:R-HSA-114697 "Activated thrombin (factor IIa) cleaves PAR3,4, activating them"
xref: Reactome:R-HSA-1181152 "Cleavage of NODAL proprotein"
xref: Reactome:R-HSA-139893 "Granzyme-B activates BID by cleavage"
xref: Reactome:R-HSA-140599 "factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides"
xref: Reactome:R-HSA-140664 "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst)"
-xref: Reactome:R-HSA-140696 "factor V -> factor Va + factor V activation peptide (thrombin catalyst)"
+xref: Reactome:R-HSA-140696 "factor V -> factor Va + factor V activation peptide"
xref: Reactome:R-HSA-140700 "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst)"
xref: Reactome:R-HSA-140736 "factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst)"
xref: Reactome:R-HSA-140769 "factor VII -> factor VIIa"
@@ -39494,7 +40879,7 @@
xref: Reactome:R-HSA-187020 "Part of pro-beta-NGF is processed to mature beta-NGF"
xref: Reactome:R-HSA-1912369 "NOTCH precursor cleaved to form mature NOTCH"
xref: Reactome:R-HSA-1912372 "Fringe-modified Pre-NOTCH is cleaved by FURIN"
-xref: Reactome:R-HSA-2022411 "Cathepsin G hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8))"
+xref: Reactome:R-HSA-2022411 "Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)"
xref: Reactome:R-HSA-2129357 "Fibrillin C-terminal processing"
xref: Reactome:R-HSA-2168923 "Collagen type XVIII endostatin release"
xref: Reactome:R-HSA-2168960 "Collagen type XVII ectodomain shedding"
@@ -39585,24 +40970,58 @@
xref: Reactome:R-HSA-9770187 "S2 Cleavage by TMPRSS2 Exposes S2' Initiating Cell-Cell Fusion"
xref: Reactome:R-HSA-977371 "Factor I inactivates Factor H-boundC3b"
xref: Reactome:R-HSA-977615 "Factor I inactivates MCP/CR1-bound C4b/C3b"
-xref: Reactome:R-HSA-9816275 "CDH1 is proteolytically cleaved in Golgi"
xref: Reactome:R-HSA-9829030 "Nascent F signal peptide is cleaved at ER membrane"
xref: Reactome:R-HSA-9829200 "F0 is cleaved, releasing F1, F2, F(110-136)"
xref: Reactome:R-HSA-9830805 "Nascent sG localizes to ER lumen, gets glycosylated"
xref: Reactome:R-HSA-9830882 "Nascent G signal peptide is cleaved at ER membrane"
xref: Reactome:R-HSA-9839367 "TGFBR3_mem cleavage by MMPs"
-xref: Reactome:R-HSA-9911236 "ELANE cleaves NOTCH2NLA"
-xref: Reactome:R-HSA-9911383 "LepB cleaves prepro-STa"
-xref: Reactome:R-HSA-9912368 "LepB cleaves pre-EltA"
-xref: Reactome:R-HSA-9912371 "LepB cleaves pre-EltB"
-xref: Reactome:R-HSA-9913329 "Autoproteolysis of DAG1 to alpha and beta chains"
-xref: Reactome:R-HSA-9926936 "EspC(54-1018) cleaves hemoglobin"
-xref: Reactome:R-HSA-9926963 "Hbp cis-autocleaves"
-xref: Reactome:R-HSA-9927009 "Hbp(53-1100) cleaves hemoglobin"
-xref: Reactome:R-HSA-9932162 "Removal of CDH1 signal peptide"
is_a: GO:0004175 ! endopeptidase activity
is_a: GO:0008236 ! serine-type peptidase activity
+property_value: skos:exactMatch EC:3.4.21.-
+property_value: skos:narrowMatch EC:3.4.21.1
+property_value: skos:narrowMatch EC:3.4.21.10
+property_value: skos:narrowMatch EC:3.4.21.102
+property_value: skos:narrowMatch EC:3.4.21.20
+property_value: skos:narrowMatch EC:3.4.21.21
+property_value: skos:narrowMatch EC:3.4.21.22
+property_value: skos:narrowMatch EC:3.4.21.26
+property_value: skos:narrowMatch EC:3.4.21.27
+property_value: skos:narrowMatch EC:3.4.21.34
+property_value: skos:narrowMatch EC:3.4.21.35
+property_value: skos:narrowMatch EC:3.4.21.36
+property_value: skos:narrowMatch EC:3.4.21.38
+property_value: skos:narrowMatch EC:3.4.21.39
+property_value: skos:narrowMatch EC:3.4.21.4
+property_value: skos:narrowMatch EC:3.4.21.41
+property_value: skos:narrowMatch EC:3.4.21.42
+property_value: skos:narrowMatch EC:3.4.21.43
+property_value: skos:narrowMatch EC:3.4.21.45
+property_value: skos:narrowMatch EC:3.4.21.46
+property_value: skos:narrowMatch EC:3.4.21.47
+property_value: skos:narrowMatch EC:3.4.21.48
+property_value: skos:narrowMatch EC:3.4.21.5
+property_value: skos:narrowMatch EC:3.4.21.53
+property_value: skos:narrowMatch EC:3.4.21.54
+property_value: skos:narrowMatch EC:3.4.21.59
+property_value: skos:narrowMatch EC:3.4.21.6
+property_value: skos:narrowMatch EC:3.4.21.61
+property_value: skos:narrowMatch EC:3.4.21.62
+property_value: skos:narrowMatch EC:3.4.21.68
+property_value: skos:narrowMatch EC:3.4.21.69
+property_value: skos:narrowMatch EC:3.4.21.7
+property_value: skos:narrowMatch EC:3.4.21.71
+property_value: skos:narrowMatch EC:3.4.21.73
+property_value: skos:narrowMatch EC:3.4.21.75
+property_value: skos:narrowMatch EC:3.4.21.78
+property_value: skos:narrowMatch EC:3.4.21.79
+property_value: skos:narrowMatch EC:3.4.21.83
+property_value: skos:narrowMatch EC:3.4.21.88
+property_value: skos:narrowMatch EC:3.4.21.9
+property_value: skos:narrowMatch EC:3.4.21.92
+property_value: skos:narrowMatch EC:3.4.21.93
+property_value: skos:narrowMatch EC:3.4.21.94
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20581" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004253
@@ -40022,6 +41441,8 @@
xref: Reactome:R-HSA-9818577 "TASP1 cleaves KMT2B"
is_a: GO:0004175 ! endopeptidase activity
is_a: GO:0070003 ! threonine-type peptidase activity
+property_value: skos:exactMatch EC:3.4.25.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004299
@@ -40066,8 +41487,12 @@
xref: Reactome:R-HSA-77333 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA"
xref: Reactome:R-HSA-77344 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA"
xref: Reactome:R-HSA-9916717 "ECHS1 mutants don't synthesize beta-hydroxyisobutyryl-CoA"
+xref: RHEA:20724
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.17
+property_value: skos:narrowMatch RHEA:20724
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29788" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004301
@@ -40104,7 +41529,10 @@
xref: Reactome:R-HSA-9915994 "14,15-EET is hydrolysed to 14,15-DHET by EPHX2"
xref: RHEA:19037
is_a: GO:0016803 ! ether hydrolase activity
+property_value: skos:exactMatch EC:3.3.2.10
+property_value: skos:exactMatch RHEA:19037
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27074" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004303
@@ -40131,9 +41559,15 @@
xref: Reactome:R-HSA-6810594 "HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1)"
xref: Reactome:R-HSA-804969 "HSD17B1 hydrogenates E1 to EST17b"
xref: Reactome:R-HSA-8862137 "HSD17B2 oxidises estradiol (E2) to estrone (E1)"
+xref: RHEA:24612
+xref: RHEA:24616
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.62
+property_value: skos:narrowMatch RHEA:24612
+property_value: skos:narrowMatch RHEA:24616
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19811" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21791" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004304
@@ -40152,6 +41586,9 @@
xref: Reactome:R-HSA-176664 "estrone + PAPS => estrone 3-sulfate + PAP"
xref: RHEA:15973
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.4
+property_value: skos:exactMatch RHEA:15973
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004305
@@ -40168,6 +41605,9 @@
xref: RHEA:13069
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.82
+property_value: skos:exactMatch RHEA:13069
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004306
@@ -40186,6 +41626,9 @@
xref: Reactome:R-HSA-1483190 "PETA and CTP are condensed to CDP-ETA by PCY2"
xref: RHEA:24592
is_a: GO:0070567 ! cytidylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.14
+property_value: skos:exactMatch RHEA:24592
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004307
@@ -40202,6 +41645,9 @@
xref: Reactome:R-HSA-1482962 "CDP-ETA and DAG are converted to PE by CEPT1/EPT1"
xref: RHEA:32943
is_a: GO:0017169 ! CDP-alcohol phosphatidyltransferase activity
+property_value: skos:exactMatch EC:2.7.8.1
+property_value: skos:exactMatch RHEA:32943
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004308
@@ -40226,6 +41672,8 @@
xref: Reactome:R-HSA-4341669 "Defective NEU1 does not hydrolyse Neu5Ac from glycoconjugates"
xref: Reactome:R-HSA-9638120 "NEU4 hydrolyses Neu5Ac from glycoconjugates"
is_a: GO:0016997 ! alpha-sialidase activity
+property_value: skos:exactMatch EC:3.2.1.18
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004309
@@ -40241,6 +41689,9 @@
xref: MetaCyc:EXOPOLYPHOSPHATASE-RXN
xref: RHEA:21528
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.11
+property_value: skos:exactMatch RHEA:21528
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004310
@@ -40248,6 +41699,8 @@
namespace: molecular_function
def: "OBSOLETE. Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate." [GOC:curators]
comment: This term was obsoleted because it represents a subreaction of squalene synthase activity ; GO:0051996.
+xref: Reactome:R-HSA-191402 "Reduction of presqualene diphosphate to form squalene"
+xref: Reactome:R-HSA-191405 "Two FPP molecules dimerize to form presqualene diphosphate"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28819" xsd:anyURI
is_obsolete: true
replaced_by: GO:0051996
@@ -40269,10 +41722,14 @@
xref: MetaCyc:FARNESYLTRANSTRANSFERASE-RXN
xref: RHEA:17653
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.29
+property_value: skos:exactMatch RHEA:17653
+property_value: skos:relatedMatch MetaCyc:PWY-5120
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28430" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004312
@@ -40287,6 +41744,9 @@
xref: Reactome:R-HSA-75872 "Conversion of malonyl-CoA and acetyl-CoA to palmitate"
xref: RHEA:14993
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.85
+property_value: skos:exactMatch RHEA:14993
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004313
@@ -40307,6 +41767,9 @@
xref: MetaCyc:ACP-S-ACETYLTRANSFER-RXN
xref: RHEA:41788
is_a: GO:0016418 ! S-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.38
+property_value: skos:exactMatch RHEA:41788
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004314
@@ -40333,6 +41796,8 @@
xref: MetaCyc:MALONYL-COA-ACP-TRANSACYL-RXN
xref: Reactome:R-HSA-8933547 "MCAT transfers Mal from Mal-CoA to NDUFAB1"
is_a: GO:0016419 ! S-malonyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.39
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004315
@@ -40363,10 +41828,17 @@
synonym: "condensing enzyme activity" BROAD [EC:2.3.1.41]
synonym: "fatty acid condensing enzyme activity" BROAD [EC:2.3.1.41]
synonym: "ketoacyl-ACP synthase activity" EXACT []
+xref: EC:2.3.1.179
xref: EC:2.3.1.41
+xref: MetaCyc:2.3.1.179-RXN
xref: MetaCyc:3-OXOACYL-ACP-SYNTH-RXN
xref: RHEA:22836
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.41
+property_value: skos:exactMatch MetaCyc:3-OXOACYL-ACP-SYNTH-RXN
+property_value: skos:exactMatch RHEA:22836
+property_value: skos:narrowMatch EC:2.3.1.179
+property_value: skos:narrowMatch MetaCyc:2.3.1.179-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21801" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26423" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -40391,9 +41863,17 @@
synonym: "NADPH-specific 3-oxoacyl-acylcarrier proteinreductase activity" RELATED [EC:1.1.1.100]
xref: EC:1.1.1.100
xref: MetaCyc:3-OXOACYL-ACP-REDUCT-RXN
+xref: MetaCyc:RXN-10659
+xref: MetaCyc:RXN-11476
+xref: MetaCyc:RXN-11480
xref: Reactome:R-HSA-8862152 "2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP"
xref: RHEA:17397
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.100
+property_value: skos:exactMatch RHEA:17397
+property_value: skos:narrowMatch MetaCyc:RXN-10659
+property_value: skos:narrowMatch MetaCyc:RXN-11476
+property_value: skos:narrowMatch MetaCyc:RXN-11480
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21876" xsd:anyURI
[Term]
@@ -40428,7 +41908,10 @@
xref: MetaCyc:ENOYL-ACP-REDUCT-NADH-RXN
xref: RHEA:10240
is_a: GO:0016631 ! enoyl-[acyl-carrier-protein] reductase [NAD(P)H] activity
+property_value: skos:exactMatch EC:1.3.1.9
+property_value: skos:exactMatch RHEA:10240
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25307" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004319
@@ -40476,6 +41959,9 @@
xref: MetaCyc:FATTY-ACYL-COA-SYNTHASE-RXN
xref: RHEA:22896
is_a: GO:0016408 ! C-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.86
+property_value: skos:exactMatch RHEA:22896
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004322
@@ -40503,7 +41989,10 @@
xref: Reactome:R-HSA-917933 "SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+"
xref: RHEA:11148
is_a: GO:0016724 ! oxidoreductase activity, acting on metal ions, oxygen as acceptor
+property_value: skos:exactMatch EC:1.16.3.1
+property_value: skos:exactMatch RHEA:11148
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20675" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004323
@@ -40534,11 +42023,12 @@
synonym: "TPNH-ferredoxin reductase activity" RELATED [EC:1.18.1.2]
xref: EC:1.18.1.2
xref: MetaCyc:1.18.1.2-RXN
-xref: Reactome:R-HSA-2395512 "FDXR transfers electrons to FDX1,2 (FDX1L)"
-xref: Reactome:R-HSA-2395517 "NADPH transfers electrons to FDXR"
xref: RHEA:20125
is_a: GO:0008937 ! ferredoxin-[NAD(P)H] reductase activity
+property_value: skos:exactMatch EC:1.18.1.2
+property_value: skos:exactMatch RHEA:20125
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29598" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004325
@@ -40558,7 +42048,10 @@
xref: Reactome:R-HSA-189465 "FECH binds Fe2+ to PRIN9 to form heme"
xref: RHEA:22584
is_a: GO:0016829 ! lyase activity
+property_value: skos:exactMatch EC:4.98.1.1
+property_value: skos:exactMatch RHEA:22584
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23371" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004326
@@ -40588,6 +42081,9 @@
xref: RHEA:10580
is_a: GO:0016881 ! acid-amino acid ligase activity
relationship: part_of GO:0046901 ! tetrahydrofolylpolyglutamate biosynthetic process
+property_value: skos:exactMatch EC:6.3.2.17
+property_value: skos:exactMatch RHEA:10580
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004327
@@ -40614,6 +42110,8 @@
xref: RHEA:21948
xref: UM-BBD_reactionID:r0873
is_a: GO:0004040 ! amidase activity
+property_value: skos:exactMatch EC:3.5.1.49
+property_value: skos:exactMatch RHEA:21948
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -40634,6 +42132,9 @@
xref: Reactome:R-HSA-6801456 "MTHFD1L transforms 10-formyl-THF to HCOOH and THF"
xref: RHEA:20221
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.3
+property_value: skos:exactMatch RHEA:20221
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004331
@@ -40647,9 +42148,12 @@
xref: EC:3.1.3.46
xref: MetaCyc:3.1.3.46-RXN
xref: Reactome:R-HSA-5628905 "TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate"
-xref: Reactome:R-HSA-70262 "PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate"
+xref: Reactome:R-HSA-70262 "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate"
xref: RHEA:17289
is_a: GO:0050308 ! sugar-phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.46
+property_value: skos:exactMatch RHEA:17289
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004332
@@ -40674,10 +42178,13 @@
xref: EC:4.1.2.13
xref: MetaCyc:F16ALDOLASE-RXN
xref: Reactome:R-HSA-71495 "Aldolase tetramers convert GA3P and DHAP to F1,6PP"
-xref: Reactome:R-HSA-71496 "Aldolase tetramer cleaves F1,6PP"
+xref: Reactome:R-HSA-71496 "D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate"
xref: RHEA:14729
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.13
+property_value: skos:exactMatch RHEA:14729
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27617" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004333
@@ -40694,6 +42201,9 @@
xref: Reactome:R-HSA-70982 "FH tetramer hydrates fumarate to L-malate"
xref: RHEA:12460
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.2
+property_value: skos:exactMatch RHEA:12460
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004334
@@ -40709,7 +42219,10 @@
xref: Reactome:R-HSA-71181 "FAH cleaves 4FAA"
xref: RHEA:10244
xref: UM-BBD_reactionID:r0107
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.2
+property_value: skos:exactMatch RHEA:10244
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004335
@@ -40727,6 +42240,9 @@
xref: RHEA:13553
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.6
+property_value: skos:exactMatch RHEA:13553
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004336
@@ -40754,6 +42270,9 @@
xref: Reactome:R-HSA-1606564 "GALC hydrolyzes GalCer"
xref: RHEA:14297
is_a: GO:0017042 ! glycosylceramidase activity
+property_value: skos:exactMatch EC:3.2.1.46
+property_value: skos:exactMatch MetaCyc:GALACTOSYLCERAMIDASE-RXN
+property_value: skos:exactMatch RHEA:14297
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25793" xsd:anyURI
[Term]
@@ -40780,6 +42299,8 @@
xref: Reactome:R-HSA-9717830 "GGPS1 hexamer transfers IPPP to GPP"
xref: RHEA:19361
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.10
+property_value: skos:exactMatch RHEA:19361
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28819" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
@@ -40803,6 +42324,8 @@
xref: EC:3.2.1.58
xref: MetaCyc:3.2.1.58-RXN
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.58
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004339
@@ -40821,7 +42344,9 @@
xref: EC:3.2.1.3
xref: MetaCyc:3.2.1.3-RXN
is_a: GO:0090599 ! alpha-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.3
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28262" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004340
@@ -40839,6 +42364,9 @@
xref: RHEA:17825
is_a: GO:0004396 ! hexokinase activity
relationship: part_of GO:0051156 ! glucose 6-phosphate metabolic process
+property_value: skos:exactMatch EC:2.7.1.2
+property_value: skos:exactMatch RHEA:17825
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004341
@@ -40854,6 +42382,9 @@
xref: MetaCyc:GLUCONOLACT-RXN
xref: RHEA:10440
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.17
+property_value: skos:exactMatch RHEA:10440
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004342
@@ -40874,7 +42405,10 @@
xref: Reactome:R-HSA-6799604 "GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P"
xref: RHEA:12172
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.99.6
+property_value: skos:exactMatch RHEA:12172
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19833" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004343
@@ -40897,6 +42431,9 @@
xref: Reactome:R-HSA-449734 "Acetylation of glucosamine 6-phosphate to GlcNAc6P"
xref: RHEA:10292
is_a: GO:0008080 ! N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.4
+property_value: skos:exactMatch RHEA:10292
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004344
@@ -40909,6 +42446,8 @@
xref: EC:1.1.99.35
xref: RHEA:24540
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.35
+property_value: skos:exactMatch RHEA:24540
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22585" xsd:anyURI
[Term]
@@ -40931,9 +42470,12 @@
synonym: "Zwischenferment" RELATED [EC:1.1.1.49]
xref: EC:1.1.1.49
xref: MetaCyc:GLU6PDEHYDROG-RXN
-xref: Reactome:R-HSA-70377 "G6PD multimers dehydrogenate G6P"
+xref: Reactome:R-HSA-70377 "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+"
xref: RHEA:15841
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.49
+property_value: skos:exactMatch RHEA:15841
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004346
@@ -40952,6 +42494,9 @@
xref: Reactome:R-HSA-71825 "G6PC hydrolyzes G6P to Glc and Pi (liver)"
xref: RHEA:16689
is_a: GO:0050309 ! sugar-terminal-phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.9
+property_value: skos:exactMatch RHEA:16689
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004347
@@ -40973,10 +42518,13 @@
synonym: "phosphosaccharomutase activity" BROAD [EC:5.3.1.9]
xref: EC:5.3.1.9
xref: MetaCyc:PGLUCISOM-RXN
-xref: Reactome:R-HSA-70471 "GPI dimer isomerizes G6P"
+xref: Reactome:R-HSA-70471 "alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate"
xref: Reactome:R-HSA-70475 "GPI dimer isomerizes Fru(6)P to G6P"
xref: RHEA:11816
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.9
+property_value: skos:exactMatch MetaCyc:PGLUCISOM-RXN
+property_value: skos:exactMatch RHEA:11816
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29187" xsd:anyURI
[Term]
@@ -41004,6 +42552,9 @@
xref: Reactome:R-HSA-1861789 "GBA3 hydrolyzes GlcCer (cytosol)"
xref: RHEA:13269
is_a: GO:0017042 ! glycosylceramidase activity
+property_value: skos:exactMatch EC:3.2.1.45
+property_value: skos:exactMatch MetaCyc:GLUCOSYLCERAMIDASE-RXN
+property_value: skos:exactMatch RHEA:13269
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25793" xsd:anyURI
[Term]
@@ -41023,6 +42574,9 @@
xref: RHEA:14877
is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor
is_a: GO:0019202 ! amino acid kinase activity
+property_value: skos:exactMatch EC:2.7.2.11
+property_value: skos:exactMatch RHEA:14877
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004350
@@ -41044,6 +42598,9 @@
xref: MetaCyc:GLUTSEMIALDEHYDROG-RXN
xref: RHEA:19541
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.41
+property_value: skos:exactMatch RHEA:19541
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004351
@@ -41065,6 +42622,9 @@
xref: Reactome:R-HSA-888577 "Synthesis of GABA by GAD2"
xref: RHEA:17785
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.15
+property_value: skos:exactMatch RHEA:17785
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004352
@@ -41091,7 +42651,11 @@
xref: MetaCyc:GLUTAMATE-DEHYDROGENASE-RXN
xref: RHEA:15133
is_a: GO:0004353 ! glutamate dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.4.1.2
+property_value: skos:exactMatch RHEA:15133
+property_value: skos:relatedMatch MetaCyc:GLUTAMATE-DEG1-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004353
@@ -41105,9 +42669,13 @@
synonym: "L-glutamate:NAD(P)+ oxidoreductase (deaminating)" RELATED [EC:1.4.1.3]
xref: EC:1.4.1.3
xref: MetaCyc:GLUTAMATE-DEHYDROGENASE-NADP+-RXN
-xref: Reactome:R-HSA-70589 "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2)"
-xref: Reactome:R-HSA-70600 "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2)"
+xref: Reactome:R-HSA-70589 "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1]"
+xref: Reactome:R-HSA-70600 "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1]"
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.3
+property_value: skos:exactMatch MetaCyc:GLUTAMATE-DEHYDROGENASE-NADP+-RXN
+property_value: skos:relatedMatch MetaCyc:GLUTAMATE-SYN2-PWY
+property_value: skos:relatedMatch MetaCyc:PWY-5766
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -41129,6 +42697,10 @@
xref: MetaCyc:GLUTDEHYD-RXN
xref: RHEA:11612
is_a: GO:0004353 ! glutamate dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.4.1.4
+property_value: skos:exactMatch MetaCyc:GLUTDEHYD-RXN
+property_value: skos:exactMatch RHEA:11612
+property_value: skos:relatedMatch MetaCyc:GLUTSYNIII-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -41155,6 +42727,10 @@
xref: MetaCyc:GLUTAMATESYN-RXN
xref: RHEA:15501
is_a: GO:0015930 ! glutamate synthase activity
+property_value: skos:exactMatch EC:1.4.1.13
+property_value: skos:exactMatch MetaCyc:GLUTAMATESYN-RXN
+property_value: skos:exactMatch RHEA:15501
+property_value: skos:relatedMatch MetaCyc:GLUTSYN-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -41170,7 +42746,10 @@
xref: Reactome:R-HSA-70606 "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]"
xref: RHEA:16169
is_a: GO:0016211 ! ammonia ligase activity
+property_value: skos:exactMatch EC:6.3.1.2
+property_value: skos:exactMatch RHEA:16169
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25543" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004357
@@ -41188,6 +42767,9 @@
xref: Reactome:R-HSA-5602892 "Defective GCLC does not ligate L-Glu to L-Cys"
xref: RHEA:13285
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.2
+property_value: skos:exactMatch RHEA:13285
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004358
@@ -41217,7 +42799,11 @@
xref: MetaCyc:GLUTAMATE-N-ACETYLTRANSFERASE-RXN
xref: RHEA:15349
is_a: GO:0140085 ! L-amino-acid N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.35
+property_value: skos:exactMatch KEGG_REACTION:R02282
+property_value: skos:exactMatch RHEA:15349
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30002" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004359
@@ -41229,9 +42815,12 @@
synonym: "L-glutaminase activity" RELATED [EC:3.5.1.2]
synonym: "L-glutamine amidohydrolase activity" RELATED [EC:3.5.1.2]
xref: EC:3.5.1.2
-xref: Reactome:R-HSA-70609 "glutamine + H2O => glutamate + NH4+ (GLS)"
+xref: Reactome:R-HSA-70609 "glutamine + H2O => glutamate + NH4+ [GLS]"
xref: RHEA:15889
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:broadMatch MetaCyc:GLUTAMIN-RXN
+property_value: skos:exactMatch EC:3.5.1.2
+property_value: skos:exactMatch RHEA:15889
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29467" xsd:anyURI
@@ -41257,6 +42846,9 @@
xref: Reactome:R-HSA-449715 "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P"
xref: RHEA:13237
is_a: GO:0070548 ! L-glutamine aminotransferase activity
+property_value: skos:exactMatch EC:2.6.1.16
+property_value: skos:exactMatch RHEA:13237
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004361
@@ -41270,8 +42862,11 @@
xref: RHEA:13389
xref: UM-BBD_reactionID:r0198
is_a: GO:0003995 ! acyl-CoA dehydrogenase activity
+property_value: skos:exactMatch EC:1.3.8.6
+property_value: skos:exactMatch RHEA:13389
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23497" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26435" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004362
@@ -41298,9 +42893,12 @@
is_a: GO:0015038 ! glutathione disulfide oxidoreductase activity
is_a: GO:0016209 ! antioxidant activity
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:exactMatch EC:1.8.1.7
+property_value: skos:exactMatch RHEA:11740
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25461" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25498" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004363
@@ -41319,12 +42917,15 @@
is_a: GO:0016881 ! acid-amino acid ligase activity
is_a: GO:1904091 ! non-ribosomal peptide synthetase activity
relationship: part_of GO:0006750 ! glutathione biosynthetic process
+property_value: skos:exactMatch EC:6.3.2.3
+property_value: skos:exactMatch RHEA:13557
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004364
name: glutathione transferase activity
namespace: molecular_function
-def: "Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group." [EC:2.5.1.18]
+def: "Catalysis of the reaction: RX + glutathione = an S-substituted glutathione + a halide anion + H+." [RHEA:16437]
synonym: "glutathione conjugation reaction" EXACT []
synonym: "glutathione S-alkyl transferase activity" RELATED [EC:2.5.1.18]
synonym: "glutathione S-alkyltransferase activity" RELATED [EC:2.5.1.18]
@@ -41346,7 +42947,12 @@
xref: Reactome:R-HSA-9026911 "LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1"
xref: Reactome:R-HSA-9748996 "GST dimers cleave AZA to 6MP"
xref: Reactome:R-HSA-9753280 "GSTs transfer GSH to NAPQI to form APAP-SG"
+xref: RHEA:16437
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.18
+property_value: skos:exactMatch RHEA:16437
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31085" xsd:anyURI
[Term]
id: GO:0004365
@@ -41366,10 +42972,13 @@
synonym: "triosephosphate dehydrogenase activity" BROAD [EC:1.2.1.12]
xref: EC:1.2.1.12
xref: MetaCyc:GAPOXNPHOSPHN-RXN
-xref: Reactome:R-HSA-70449 "GADPH tetramer dehydrogenates GA3P"
+xref: Reactome:R-HSA-70449 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+"
xref: Reactome:R-HSA-70482 "GAPDH tetramers reduce 1,3BPG to GA3P"
xref: RHEA:10300
is_a: GO:0043891 ! glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (phosphorylating) activity
+property_value: skos:exactMatch EC:1.2.1.12
+property_value: skos:exactMatch RHEA:10300
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004366
@@ -41394,6 +43003,9 @@
xref: Reactome:R-HSA-75886 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated]"
xref: RHEA:15325
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.15
+property_value: skos:exactMatch RHEA:15325
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004368
@@ -41411,7 +43023,10 @@
xref: Reactome:R-HSA-188467 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)"
xref: RHEA:18977
is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.1.5.3
+property_value: skos:exactMatch RHEA:18977
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25984" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004369
@@ -41429,6 +43044,9 @@
xref: MetaCyc:GLYCEROL-3-PHOSPHATE-OXIDASE-RXN
xref: RHEA:18369
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.21
+property_value: skos:exactMatch RHEA:18369
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004370
@@ -41448,6 +43066,9 @@
xref: RHEA:21644
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.30
+property_value: skos:exactMatch RHEA:21644
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004371
@@ -41464,6 +43085,9 @@
xref: RHEA:15773
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.29
+property_value: skos:exactMatch RHEA:15773
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004372
@@ -41481,6 +43105,9 @@
xref: Reactome:R-HSA-5694137 "PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser"
xref: RHEA:15481
is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity
+property_value: skos:broadMatch EC:2.1.2.1
+property_value: skos:exactMatch MetaCyc:GLYOHMETRANS-RXN
+property_value: skos:exactMatch RHEA:15481
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30653" xsd:anyURI
[Term]
@@ -41507,7 +43134,10 @@
xref: RHEA:18549
is_a: GO:0033840 ! alpha-1,4-glucan glucosyltransferase (NDP-glucose donor) activity
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.11
+property_value: skos:exactMatch RHEA:18549
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28271" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004374
@@ -41539,6 +43169,12 @@
xref: Reactome:R-HSA-5693967 "PXLP-K754-GLDC dimer decarboxylates Gly"
xref: RHEA:24304
is_a: GO:0016642 ! oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
+property_value: skos:broadMatch EC:1.4.1.27
+property_value: skos:broadMatch MetaCyc:GCVMULTI-RXN
+property_value: skos:broadMatch RHEA:27758
+property_value: skos:exactMatch EC:1.4.4.2
+property_value: skos:exactMatch MetaCyc:GCVP-RXN
+property_value: skos:exactMatch RHEA:24304
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30262" xsd:anyURI
[Term]
@@ -41570,6 +43206,9 @@
xref: RHEA:29523
is_a: GO:0000026 ! alpha-1,2-mannosyltransferase activity
is_a: GO:0120562 ! GlcNAc(2)-PP-Dol mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.131
+property_value: skos:exactMatch RHEA:29523
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30326" xsd:anyURI
[Term]
@@ -41588,7 +43227,10 @@
xref: RHEA:29515
is_a: GO:0000033 ! alpha-1,3-mannosyltransferase activity
is_a: GO:0120562 ! GlcNAc(2)-PP-Dol mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.132
+property_value: skos:exactMatch RHEA:29515
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28212" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30326" xsd:anyURI
[Term]
@@ -41613,6 +43255,9 @@
xref: RHEA:15521
is_a: GO:0016410 ! N-acyltransferase activity
is_a: GO:0019107 ! myristoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.97
+property_value: skos:exactMatch RHEA:15521
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004380
@@ -41640,6 +43285,9 @@
xref: RHEA:19021
is_a: GO:0008376 ! acetylgalactosaminyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.40
+property_value: skos:exactMatch RHEA:19021
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004381
@@ -41668,6 +43316,9 @@
xref: Reactome:R-HSA-9034053 "sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen"
xref: RHEA:14349
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.37
+property_value: skos:exactMatch RHEA:14349
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004382
@@ -41684,6 +43335,9 @@
xref: MetaCyc:GUANOSINE-DIPHOSPHATASE-RXN
xref: RHEA:22156
is_a: GO:0017110 ! nucleoside diphosphate phosphatase activity
+property_value: skos:exactMatch EC:3.6.1.42
+property_value: skos:exactMatch RHEA:22156
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004383
@@ -41703,6 +43357,9 @@
is_a: GO:0009975 ! cyclase activity
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
relationship: part_of GO:0006182 ! cGMP biosynthetic process
+property_value: skos:exactMatch EC:4.6.1.2
+property_value: skos:exactMatch RHEA:13665
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004384
@@ -41740,6 +43397,9 @@
is_a: GO:0050145 ! nucleoside monophosphate kinase activity
relationship: part_of GO:0046037 ! GMP metabolic process
relationship: part_of GO:0046710 ! GDP metabolic process
+property_value: skos:exactMatch EC:2.7.4.8
+property_value: skos:exactMatch MetaCyc:GUANYL-KIN-RXN
+property_value: skos:exactMatch RHEA:20780
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27917" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29533" xsd:anyURI
@@ -41782,7 +43442,10 @@
xref: Reactome:R-HSA-189398 "HMOX1 dimer, HMOX2 cleave heme"
xref: RHEA:21764
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.18
+property_value: skos:exactMatch RHEA:21764
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21106" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004394
@@ -41794,7 +43457,7 @@
synonym: "heparin 2-sulfotransferase activity" RELATED []
synonym: "heparin-sulphate 2-sulphotransferase activity" RELATED []
xref: MetaCyc:RXN-11558
-xref: Reactome:R-HSA-2076508 "HS2ST1 trimer sulfates IdoA at C2 in heparan sulfate"
+xref: Reactome:R-HSA-2076508 "HS2ST1 sulfates IdoA at C2 in heparan sulfate"
is_a: GO:0034483 ! heparan sulfate sulfotransferase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24749" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28380" xsd:anyURI
@@ -41830,6 +43493,9 @@
xref: RHEA:22740
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.1
+property_value: skos:exactMatch RHEA:22740
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004397
@@ -41846,6 +43512,9 @@
xref: Reactome:R-HSA-70899 "histidine => urocanate + NH4+"
xref: RHEA:21232
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.3
+property_value: skos:exactMatch RHEA:21232
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004398
@@ -41860,6 +43529,9 @@
xref: Reactome:R-HSA-977301 "Histidine is decarboxylated to histamine"
xref: RHEA:20840
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.22
+property_value: skos:exactMatch RHEA:20840
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004399
@@ -41870,6 +43542,9 @@
xref: MetaCyc:RXN-8001
xref: RHEA:20641
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.23
+property_value: skos:exactMatch MetaCyc:RXN-8001
+property_value: skos:exactMatch RHEA:20641
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -41892,6 +43567,9 @@
xref: MetaCyc:HISTAMINOTRANS-RXN
xref: RHEA:23744
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.9
+property_value: skos:exactMatch RHEA:23744
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004401
@@ -41909,6 +43587,9 @@
xref: MetaCyc:HISTIDPHOS-RXN
xref: RHEA:14465
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.15
+property_value: skos:exactMatch RHEA:14465
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004402
@@ -41947,10 +43628,10 @@
xref: Reactome:R-HSA-3697920 "CLOCK acetylates lysine-10 of histone H3, H4"
xref: Reactome:R-HSA-5144542 "CLOCK acetylates lysine-15 of histone H3, H4"
xref: Reactome:R-HSA-5250938 "B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9"
-xref: Reactome:R-HSA-9926482 "CREBBP, EP300 acetylate MITF-M"
xref: RHEA:21992
is_a: GO:0061733 ! protein-lysine-acetyltransferase activity
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:exactMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -41972,6 +43653,8 @@
xref: Reactome:R-HSA-6805650 "MTA2-NuRD complex deacetylates TP53"
is_a: GO:0033558 ! protein lysine deacetylase activity
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:broadMatch EC:2.3.1.-
+property_value: skos:broadMatch EC:3.5.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22295" xsd:anyURI
[Term]
@@ -41990,6 +43673,9 @@
xref: RHEA:22648
is_a: GO:0016846 ! carbon-sulfur lyase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:4.4.1.17
+property_value: skos:exactMatch RHEA:22648
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004409
@@ -42008,6 +43694,9 @@
xref: MetaCyc:HOMOACONITATE-HYDRATASE-RXN
xref: RHEA:15485
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.36
+property_value: skos:exactMatch RHEA:15485
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004410
@@ -42024,6 +43713,9 @@
xref: MetaCyc:HOMOCITRATE-SYNTHASE-RXN
xref: RHEA:12929
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.14
+property_value: skos:exactMatch RHEA:12929
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004411
@@ -42045,6 +43737,9 @@
xref: RHEA:15449
xref: UM-BBD_reactionID:r0105
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.5
+property_value: skos:exactMatch RHEA:15449
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004412
@@ -42055,6 +43750,9 @@
xref: MetaCyc:HOMOSERDEHYDROG-RXN
xref: RHEA:15761
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.3
+property_value: skos:exactMatch RHEA:15761
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004413
@@ -42070,6 +43768,9 @@
xref: RHEA:13985
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019202 ! amino acid kinase activity
+property_value: skos:exactMatch EC:2.7.1.39
+property_value: skos:exactMatch RHEA:13985
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004414
@@ -42087,6 +43788,9 @@
xref: MetaCyc:HOMOSERINE-O-ACETYLTRANSFERASE-RXN
xref: RHEA:13701
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.31
+property_value: skos:exactMatch RHEA:13701
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004415
@@ -42101,14 +43805,15 @@
synonym: "hyaluronoglucosidase activity" RELATED [EC:3.2.1.35]
xref: EC:3.2.1.35
xref: MetaCyc:3.2.1.35-RXN
-xref: Reactome:R-HSA-1793209 "HYAL1-4 hydrolyze chondroitin chains"
+xref: Reactome:R-HSA-1793209 "HYAL1 hydrolyses Chondroitin chains"
xref: Reactome:R-HSA-2160874 "HYAL1 hydrolyses (HA)50"
-xref: Reactome:R-HSA-2160892 "HYAL2 hydrolyses HA into 20kDa fragments"
+xref: Reactome:R-HSA-2160892 "Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments"
xref: Reactome:R-HSA-2318585 "Defective HYAL1 does not hydrolyse Chondroitin chains"
-xref: Reactome:R-HSA-5693356 "CEMIP hydrolyzes HA"
+xref: Reactome:R-HSA-5693356 "CEMIP hydrolyses HA"
xref: Reactome:R-HSA-9036077 "Defective HYAL1 does not hydrolyse (HA)50"
-xref: Reactome:R-HSA-9941055 "SPAM1 randomly cleaves HA"
is_a: GO:0015929 ! hexosaminidase activity
+property_value: skos:exactMatch EC:3.2.1.35
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004416
@@ -42124,7 +43829,10 @@
xref: Reactome:R-HSA-6783221 "HAGH hydrolyses (R)-S-LGSH to GSH and LACT"
xref: RHEA:21864
is_a: GO:0016790 ! thiolester hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.6
+property_value: skos:exactMatch RHEA:21864
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004417
@@ -42140,6 +43848,9 @@
xref: RHEA:24212
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.50
+property_value: skos:exactMatch RHEA:24212
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004418
@@ -42163,6 +43874,9 @@
xref: Reactome:R-HSA-189406 "4 PBGs bind to form HMB"
xref: RHEA:13185
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.61
+property_value: skos:exactMatch RHEA:13185
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004419
@@ -42185,6 +43899,9 @@
xref: Reactome:R-HSA-74180 "HMG CoA => acetoacetic acid + acetyl CoA"
xref: RHEA:24404
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.4
+property_value: skos:exactMatch RHEA:24404
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004420
@@ -42201,7 +43918,10 @@
xref: Reactome:R-HSA-191352 "HMGCR dimer reduces bHMG-CoA to MVA"
xref: RHEA:15989
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.34
+property_value: skos:exactMatch RHEA:15989
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21411" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004421
@@ -42229,6 +43949,9 @@
xref: Reactome:R-HSA-73918 "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH"
xref: RHEA:10188
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.10
+property_value: skos:exactMatch RHEA:10188
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004422
@@ -42255,6 +43978,8 @@
xref: MetaCyc:HYPOXANPRIBOSYLTRAN-RXN
xref: RHEA:17973
is_a: GO:0106130 ! purine phosphoribosyltransferase activity
+property_value: skos:broadMatch EC:2.4.2.8
+property_value: skos:exactMatch RHEA:17973
[Term]
id: GO:0004423
@@ -42282,6 +44007,8 @@
xref: Reactome:R-HSA-2262743 "Defective IDS does not hydrolyse dermatan sulfate (Chebi:63517 chain)"
xref: Reactome:R-HSA-9036046 "Defective IDS does not hydrolyse Heparan sulfate chain(5)"
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.13
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004424
@@ -42297,6 +44024,9 @@
xref: MetaCyc:IMIDPHOSDEHYD-RXN
xref: RHEA:11040
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.19
+property_value: skos:exactMatch RHEA:11040
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004425
@@ -42312,6 +44042,9 @@
xref: MetaCyc:IGPSYN-RXN
xref: RHEA:23476
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.48
+property_value: skos:exactMatch RHEA:23476
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004427
@@ -42330,7 +44063,10 @@
xref: Reactome:R-HSA-71732 "PPA1 hydrolyzes pyrophosphate to orthophosphate"
xref: RHEA:24576
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.1
+property_value: skos:exactMatch RHEA:24576
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004428
@@ -42369,7 +44105,10 @@
xref: Reactome:R-HSA-1676185 "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane"
xref: RHEA:19877
is_a: GO:0052742 ! phosphatidylinositol kinase activity
+property_value: skos:exactMatch EC:2.7.1.67
+property_value: skos:exactMatch RHEA:19877
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28336" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004432
@@ -42402,6 +44141,7 @@
synonym: "monophosphatidylinositol phosphodiesterase activity" BROAD [EC:3.1.4.11]
synonym: "phosphatidylinositol phospholipase C activity" BROAD []
synonym: "phosphatidylinositol-4,5-bisphosphate hydrolysis" RELATED []
+synonym: "phosphatidylinositol-4,5-bisphosphate phospholipase C-type activity" EXACT []
synonym: "phosphoinositidase C activity" RELATED [EC:3.1.4.11]
synonym: "phosphoinositide phospholipase C activity" RELATED [EC:3.1.4.11]
synonym: "PI-PLC activity" RELATED [EC:3.1.4.11]
@@ -42421,8 +44161,11 @@
xref: Reactome:R-HSA-9032478 "EPOR-associated PLCG hydrolyzes 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate"
xref: Reactome:R-HSA-9717205 "GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG"
xref: RHEA:33179
-is_a: GO:0004629 ! phospholipase C activity
+is_a: GO:0004629 ! C-type glycerophospholipase activity
+property_value: skos:exactMatch EC:3.1.4.11
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29643" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30949" xsd:anyURI
[Term]
id: GO:0004436
@@ -42438,6 +44181,9 @@
xref: MetaCyc:3.1.4.10-RXN
xref: RHEA:17093
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
+property_value: skos:exactMatch EC:4.6.1.13
+property_value: skos:exactMatch RHEA:17093
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004437
@@ -42479,7 +44225,10 @@
xref: Reactome:R-HSA-6809975 "PI3P is dephosphorylated to PI by the MTMR2:SBF2 tetramer at the plasma membrane"
xref: RHEA:12316
is_a: GO:0052744 ! phosphatidylinositol monophosphate phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.64
+property_value: skos:exactMatch RHEA:12316
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24252" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004439
@@ -42504,6 +44253,9 @@
xref: RHEA:22764
is_a: GO:0034595 ! phosphatidylinositol phosphate 5-phosphatase activity
is_a: GO:0106019 ! phosphatidylinositol-4,5-bisphosphate phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.36
+property_value: skos:exactMatch RHEA:22764
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004441
@@ -42518,6 +44270,9 @@
xref: Reactome:R-HSA-1855208 "I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol"
xref: RHEA:15553
is_a: GO:0016312 ! inositol bisphosphate phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.57
+property_value: skos:exactMatch RHEA:15553
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004442
@@ -42578,6 +44333,7 @@
synonym: "type II inositol-1,4,5-trisphosphate 5-phosphatase activity" NARROW []
xref: EC:3.1.3.56
is_a: GO:0046030 ! inositol trisphosphate phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.56
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -42601,8 +44357,11 @@
xref: MetaCyc:IODIDE-PEROXIDASE-RXN
xref: RHEA:23336
is_a: GO:0140905 ! haloperoxidase activity
+property_value: skos:exactMatch EC:1.11.1.8
+property_value: skos:exactMatch RHEA:23336
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21027" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23587" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004448
@@ -42638,8 +44397,12 @@
xref: Reactome:R-HSA-70967 "IDH3 complex decarboxylates isocitrate"
xref: RHEA:23632
is_a: GO:0004448 ! isocitrate dehydrogenase [NAD(P)+] activity
+property_value: skos:broadMatch MetaCyc:ISOCITRATE-DEHYDROGENASE-NAD+-RXN
+property_value: skos:exactMatch EC:1.1.1.41
+property_value: skos:exactMatch RHEA:23632
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23235" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004450
@@ -42668,7 +44431,10 @@
xref: Reactome:R-HSA-450984 "IDH2 dimer decarboxylates isocitrate"
xref: RHEA:19629
is_a: GO:0004448 ! isocitrate dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.1.1.42
+property_value: skos:exactMatch RHEA:19629
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23235" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004451
@@ -42687,6 +44453,9 @@
xref: MetaCyc:ISOCIT-CLEAV-RXN
xref: RHEA:13245
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.1
+property_value: skos:exactMatch RHEA:13245
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004452
@@ -42705,6 +44474,9 @@
xref: Reactome:R-HSA-191382 "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate"
xref: RHEA:23284
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.2
+property_value: skos:exactMatch RHEA:23284
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004453
@@ -42721,6 +44493,9 @@
xref: MetaCyc:JUVENILE-HORMONE-ESTERASE-RXN
xref: RHEA:16393
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.59
+property_value: skos:exactMatch RHEA:16393
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004454
@@ -42737,6 +44512,9 @@
xref: RHEA:18145
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.3
+property_value: skos:exactMatch RHEA:18145
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004455
@@ -42758,6 +44536,9 @@
xref: MetaCyc:ACETOLACTREDUCTOISOM-RXN
xref: RHEA:22068
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.86
+property_value: skos:exactMatch RHEA:22068
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004456
@@ -42776,6 +44557,9 @@
xref: MetaCyc:PGLUCONDEHYDRAT-RXN
xref: RHEA:17277
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.12
+property_value: skos:exactMatch RHEA:17277
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004457
@@ -42802,6 +44586,9 @@
xref: RHEA:13521
is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor
is_a: GO:0047809 ! D-lactate dehydrogenase activity
+property_value: skos:exactMatch EC:1.1.2.4
+property_value: skos:exactMatch RHEA:13521
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004459
@@ -42819,7 +44606,10 @@
xref: RHEA:23444
is_a: GO:0102443 ! L-2-hydroxycarboxylate dehydrogenase (NAD+) activity
is_a: GO:0140171 ! L-lactate dehydrogenase activity
+property_value: skos:exactMatch EC:1.1.1.27
+property_value: skos:exactMatch RHEA:23444
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30132" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004460
@@ -42844,6 +44634,9 @@
xref: RHEA:19909
is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor
is_a: GO:0140171 ! L-lactate dehydrogenase activity
+property_value: skos:exactMatch EC:1.1.2.3
+property_value: skos:exactMatch RHEA:19909
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004461
@@ -42861,6 +44654,9 @@
xref: Reactome:R-HSA-5653878 "B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac"
xref: RHEA:12404
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.22
+property_value: skos:exactMatch RHEA:12404
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004462
@@ -42880,6 +44676,9 @@
xref: Reactome:R-HSA-5694071 "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH"
xref: RHEA:19069
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.5
+property_value: skos:exactMatch RHEA:19069
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004463
@@ -42898,6 +44697,9 @@
xref: Reactome:R-HSA-266072 "LTA4 is hydolysed to LTB4 by LTA4H"
xref: RHEA:22324
is_a: GO:0016803 ! ether hydrolase activity
+property_value: skos:exactMatch EC:3.3.2.6
+property_value: skos:exactMatch RHEA:22324
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004464
@@ -42919,10 +44721,12 @@
xref: EC:4.4.1.20
xref: KEGG_REACTION:R03059
xref: MetaCyc:LEUKOTRIENE-C4-SYNTHASE-RXN
-xref: Reactome:R-HSA-2162019 "LTA4 is converted to EXA4 by ALOX15"
xref: Reactome:R-HSA-266050 "LTA4 is converted to LTC4 by LTC4S"
xref: RHEA:17617
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.20
+property_value: skos:exactMatch RHEA:17617
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004465
@@ -42945,8 +44749,10 @@
xref: Reactome:R-HSA-8979996 "LIPs hydrolyze TG to DAG and LCFA"
xref: Reactome:R-HSA-8980228 "LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA"
is_a: GO:0004806 ! triacylglycerol lipase activity
+property_value: skos:exactMatch EC:3.1.1.34
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28339" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004466
@@ -42962,7 +44768,10 @@
xref: MetaCyc:LONG-CHAIN-ACYL-COA-DEHYDROGENASE-RXN
xref: RHEA:17721
is_a: GO:0003995 ! acyl-CoA dehydrogenase activity
+property_value: skos:exactMatch EC:1.3.8.8
+property_value: skos:exactMatch RHEA:17721
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004467
@@ -43008,6 +44817,10 @@
xref: RHEA:15421
is_a: GO:0120515 ! fatty acid-CoA ligase activity
relationship: part_of GO:0001676 ! long-chain fatty acid metabolic process
+property_value: skos:exactMatch EC:6.2.1.3
+property_value: skos:exactMatch MetaCyc:RXN-7904
+property_value: skos:exactMatch RHEA:15421
+property_value: skos:relatedMatch MetaCyc:PWY-5143
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18967" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20462" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25799" xsd:anyURI
@@ -43032,6 +44845,9 @@
xref: Reactome:R-HSA-5693001 "NAT8,8B acetylate BACE1"
xref: RHEA:14417
is_a: GO:0140085 ! L-amino-acid N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.32
+property_value: skos:exactMatch RHEA:14417
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004470
@@ -43064,6 +44880,10 @@
xref: RHEA:12653
is_a: GO:0004470 ! malic enzyme activity
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.1.1.38
+property_value: skos:exactMatch EC:1.1.1.39
+property_value: skos:exactMatch MetaCyc:1.1.1.39-RXN
+property_value: skos:exactMatch RHEA:12653
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28245" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
@@ -43090,6 +44910,9 @@
xref: RHEA:18253
is_a: GO:0004470 ! malic enzyme activity
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.40
+property_value: skos:exactMatch MetaCyc:MALIC-NADP-RXN
+property_value: skos:exactMatch RHEA:18253
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28245" xsd:anyURI
[Term]
@@ -43111,6 +44934,9 @@
xref: MetaCyc:MALSYN-RXN
xref: RHEA:18181
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.9
+property_value: skos:exactMatch RHEA:18181
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004475
@@ -43133,7 +44959,10 @@
xref: Reactome:R-HSA-446221 "GMPPB converts Mannose-1-phosphate to GDP-Mannose"
xref: RHEA:15229
is_a: GO:0070568 ! guanylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.13
+property_value: skos:exactMatch RHEA:15229
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23283" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004476
@@ -43153,6 +44982,9 @@
xref: Reactome:R-HSA-532549 "MPI isomerises Fru6P to Man6P"
xref: RHEA:12356
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.8
+property_value: skos:exactMatch RHEA:12356
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004477
@@ -43170,6 +45002,9 @@
xref: Reactome:R-HSA-6801328 "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF"
xref: RHEA:23700
is_a: GO:0019238 ! cyclohydrolase activity
+property_value: skos:exactMatch EC:3.5.4.9
+property_value: skos:exactMatch RHEA:23700
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004478
@@ -43192,6 +45027,9 @@
xref: Reactome:R-HSA-5603114 "MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met"
xref: RHEA:21080
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.6
+property_value: skos:exactMatch RHEA:21080
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004479
@@ -43222,6 +45060,9 @@
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
relationship: part_of GO:0006413 ! translational initiation
relationship: part_of GO:0071951 ! conversion of methionyl-tRNA to N-formyl-methionyl-tRNA
+property_value: skos:exactMatch EC:2.1.2.9
+property_value: skos:exactMatch RHEA:24380
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004481
@@ -43235,6 +45076,9 @@
xref: MetaCyc:2.1.1.16-RXN
xref: RHEA:17549
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.16
+property_value: skos:exactMatch RHEA:17549
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004482
@@ -43260,7 +45104,9 @@
is_a: GO:0008174 ! mRNA methyltransferase activity
relationship: part_of GO:0006370 ! 7-methylguanosine mRNA capping
relationship: part_of GO:0106005 ! RNA 5'-cap (guanine-N7)-methylation
+property_value: skos:exactMatch EC:2.1.1.56
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25788" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004483
@@ -43281,8 +45127,11 @@
xref: Reactome:R-HSA-9694521 "nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand)"
xref: Reactome:R-HSA-9694721 "nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand)"
xref: Reactome:R-HSA-9834003 "L protein acts as a cap 2'-O-methyltransferase to modify RSV mRNAs"
+xref: RHEA:67020
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008173 ! RNA methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.57
+property_value: skos:narrowMatch RHEA:67020
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27387" xsd:anyURI
[Term]
@@ -43302,6 +45151,9 @@
xref: Reactome:R-HSA-9815529 "nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs"
xref: RHEA:54592
is_a: GO:0008192 ! RNA guanylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.50
+property_value: skos:exactMatch RHEA:54592
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004485
@@ -43318,11 +45170,14 @@
xref: EC:6.4.1.4
xref: KEGG_REACTION:R04138
xref: MetaCyc:METHYLCROTONYL-COA-CARBOXYLASE-RXN
-xref: Reactome:R-HSA-508308 "beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA)"
-xref: Reactome:R-HSA-70773 "beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA)"
+xref: Reactome:R-HSA-508308 "beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + CO2 (MCCA)"
+xref: Reactome:R-HSA-70773 "beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA]"
xref: Reactome:R-HSA-9909466 "MCCC mutants don't synthesize beta-methylglutaconyl-CoA"
xref: RHEA:13589
is_a: GO:0016421 ! CoA carboxylase activity
+property_value: skos:exactMatch EC:6.4.1.4
+property_value: skos:exactMatch RHEA:13589
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004486
@@ -43332,6 +45187,8 @@
comment: This term was obsoleted because it is an unnecessary grouping term.
synonym: "5,10-methylene-THF dehydrogenase activity" EXACT [GOC:vw]
synonym: "N5,N10-methylenetetrahydrofolate dehydrogenase activity" RELATED []
+xref: Reactome:R-HSA-200644 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+"
+xref: Reactome:R-HSA-200718 "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
is_obsolete: true
@@ -43351,6 +45208,9 @@
xref: Reactome:R-HSA-6801462 "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF"
xref: RHEA:22892
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.15
+property_value: skos:exactMatch RHEA:22892
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004488
@@ -43362,10 +45222,11 @@
xref: EC:1.5.1.5
xref: KEGG_REACTION:R01220
xref: MetaCyc:METHYLENETHFDEHYDROG-NADP-RXN
-xref: Reactome:R-HSA-200644 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+"
-xref: Reactome:R-HSA-200718 "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG"
xref: RHEA:22812
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.5
+property_value: skos:exactMatch RHEA:22812
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004489
@@ -43408,6 +45269,8 @@
xref: MetaCyc:1.5.1.20-RXN
xref: Reactome:R-HSA-200676 "MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG"
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.20
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004490
@@ -43426,20 +45289,30 @@
xref: Reactome:R-HSA-9914271 "AUH mutants don't synthesize 3-hydroxy-methylglutaryl-CoA"
xref: RHEA:21536
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.18
+property_value: skos:exactMatch RHEA:21536
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004491
name: methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
namespace: molecular_function
-def: "Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+. Can also use malonate (3-oxopropanoate) as a substrate. The reaction occurs in two steps with the decarboxylation process preceding CoA-binding. Bicarbonate rather than CO2 is released as a final product." [EC:1.2.1.27, PMID:2768248]
+def: "Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + hydrogencarbonate + NADH + H+. Can also use malonate (3-oxopropanoate) as a substrate. The reaction occurs in two steps with the decarboxylation process preceding CoA-binding. Bicarbonate rather than CO2 is released as a final product." [EC:1.2.1.27, PMID:2768248]
synonym: "methylmalonate-semialdehyde dehydrogenase (acylating) activity" RELATED []
synonym: "MMSA dehydrogenase activity" RELATED [EC:1.2.1.27]
synonym: "MSDH activity" RELATED [EC:1.2.1.27]
xref: EC:1.2.1.27
xref: MetaCyc:1.2.1.27-RXN
-xref: Reactome:R-HSA-70893 "methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+"
+xref: Reactome:R-HSA-70893 "methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+"
+xref: RHEA:20804
+xref: RHEA:76615
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.27
+property_value: skos:narrowMatch RHEA:20804
+property_value: skos:narrowMatch RHEA:76615
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25638" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30853" xsd:anyURI
[Term]
id: GO:0004492
@@ -43451,8 +45324,18 @@
synonym: "(S)-methylmalonyl-CoA carboxy-lyase activity" NARROW []
synonym: "ethylmalonyl-CoA decarboxylase activity" NARROW []
synonym: "methylmalonyl-coenzyme A decarboxylase activity" NARROW []
+xref: EC:4.1.1.94
xref: MetaCyc:METHYLMALONYL-COA-DECARBOXYLASE-RXN
+xref: RHEA:27666
+xref: RHEA:32131
+xref: RHEA:59540
+xref: RHEA:61340
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:narrowMatch EC:4.1.1.94
+property_value: skos:narrowMatch RHEA:27666
+property_value: skos:narrowMatch RHEA:32131
+property_value: skos:narrowMatch RHEA:59540
+property_value: skos:narrowMatch RHEA:61340
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21629" xsd:anyURI
[Term]
@@ -43471,6 +45354,9 @@
xref: Reactome:R-HSA-71020 "D-methylmalonyl-CoA <=> L-methylmalonyl-CoA"
xref: RHEA:20553
is_a: GO:0016854 ! racemase and epimerase activity
+property_value: skos:exactMatch EC:5.1.99.1
+property_value: skos:exactMatch RHEA:20553
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004494
@@ -43491,6 +45377,9 @@
xref: RHEA:22888
xref: UM-BBD_reactionID:r0922
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.2
+property_value: skos:exactMatch RHEA:22888
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004495
@@ -43522,6 +45411,9 @@
xref: RHEA:17065
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.36
+property_value: skos:exactMatch RHEA:17065
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004497
@@ -43565,6 +45457,9 @@
xref: Reactome:R-HSA-5602272 "Defective CYP4F22 does not 20-hydroxylate TrXA3"
xref: Reactome:R-HSA-5602295 "CYP4F22 20-hydroxylates TrXA3"
xref: Reactome:R-HSA-5605147 "Defective CYP1B1 does not 4-hydroxylate EST17b"
+xref: Reactome:R-HSA-5662662 "Tyrosinase oxidises tyrosine to dopaquinone"
+xref: Reactome:R-HSA-5662692 "Dopa is oxidized to dopaquinone by TYR"
+xref: Reactome:R-HSA-5663050 "DHI and DHICA polymerize forming eumelanin"
xref: Reactome:R-HSA-76354 "Vinyl chloride is oxidized to 2-Chloroethylene oxide"
xref: Reactome:R-HSA-76373 "N-hydroxylation of 4-aminobiphenyl"
xref: Reactome:R-HSA-76386 "CYP1A2 S-demethylates 6MMP"
@@ -43596,6 +45491,7 @@
xref: Reactome:R-HSA-9915993 "Arachidonate is hydroxylated to 18-HETE by CYP(1)"
xref: Reactome:R-HSA-9915997 "Arachidonate is epoxidated to 14,15-EET by CYP(5)"
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:broadMatch EC:1.-.-.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30165" xsd:anyURI
[Term]
@@ -43623,6 +45519,9 @@
xref: RHEA:20573
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
relationship: part_of GO:0036378 ! calcitriol biosynthetic process from calciol
+property_value: skos:exactMatch EC:1.14.15.18
+property_value: skos:exactMatch RHEA:20573
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004499
@@ -43650,6 +45549,8 @@
xref: Reactome:R-HSA-5602966 "Defective FMO3 does not N-oxidise TMA"
xref: RHEA:24468
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:broadMatch EC:1.14.13.8
+property_value: skos:exactMatch RHEA:24468
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27695" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
@@ -43678,6 +45579,9 @@
xref: Reactome:R-HSA-209891 "Dopamine is oxidised to noradrenaline"
xref: RHEA:19117
is_a: GO:0016715 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.17.1
+property_value: skos:exactMatch RHEA:19117
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004501
@@ -43694,6 +45598,9 @@
xref: RHEA:14021
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.22
+property_value: skos:exactMatch RHEA:14021
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004502
@@ -43710,6 +45617,9 @@
xref: Reactome:R-HSA-71200 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O"
xref: RHEA:20545
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.9
+property_value: skos:exactMatch RHEA:20545
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004503
@@ -43740,8 +45650,12 @@
synonym: "tyrosine-dopa oxidase activity" RELATED [EC:1.14.18.1]
xref: EC:1.14.18.1
xref: MetaCyc:MONOPHENOL-MONOOXYGENASE-RXN
+xref: RHEA:18117
is_a: GO:0016716 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.18.1
+property_value: skos:narrowMatch RHEA:18117
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21024" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004504
@@ -43764,6 +45678,9 @@
xref: MetaCyc:PEPTIDYLGLYCINE-MONOOXYGENASE-RXN
xref: RHEA:21452
is_a: GO:0016715 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.17.3
+property_value: skos:exactMatch RHEA:21452
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004505
@@ -43782,7 +45699,10 @@
xref: RHEA:20273
is_a: GO:0016714 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
relationship: part_of GO:0019293 ! L-tyrosine biosynthetic process, by oxidation of phenylalanine
+property_value: skos:exactMatch EC:1.14.16.1
+property_value: skos:exactMatch RHEA:20273
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20583" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004506
@@ -43802,6 +45722,9 @@
xref: Reactome:R-HSA-191299 "Squalene is oxidized to its epoxide"
xref: RHEA:25282
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.17
+property_value: skos:exactMatch RHEA:25282
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004507
@@ -43827,6 +45750,9 @@
xref: RHEA:15629
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.15.4
+property_value: skos:exactMatch RHEA:15629
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004508
@@ -43846,6 +45772,8 @@
synonym: "steroid 17alphahydroxylase/17,20 lyase activity" RELATED [EC:1.14.14.19]
synonym: "steroid,hydrogen-donor:oxygen oxidoreductase (17alpha-hydroxylating)" RELATED [EC:1.14.14.19]
xref: EC:1.14.14.19
+xref: EC:1.14.14.32
+xref: MetaCyc:4.1.2.30-RXN
xref: MetaCyc:STEROID-17-ALPHA-MONOOXYGENASE-RXN
xref: Reactome:R-HSA-193068 "CYP17A1 17-hydroxylates PREG"
xref: Reactome:R-HSA-193070 "CYP17A1 cleaves 17aHPREG to DHA"
@@ -43857,6 +45785,11 @@
xref: RHEA:65760
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.19
+property_value: skos:exactMatch MetaCyc:STEROID-17-ALPHA-MONOOXYGENASE-RXN
+property_value: skos:exactMatch RHEA:65760
+property_value: skos:narrowMatch EC:1.14.14.32
+property_value: skos:narrowMatch MetaCyc:4.1.2.30-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27671" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29041" xsd:anyURI
@@ -43877,7 +45810,10 @@
xref: RHEA:65612
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.16
+property_value: skos:exactMatch RHEA:65612
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29041" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004510
@@ -43894,6 +45830,9 @@
xref: Reactome:R-HSA-209828 "Tryptophan is hydroxylated"
xref: RHEA:16709
is_a: GO:0016714 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.16.4
+property_value: skos:exactMatch RHEA:16709
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004511
@@ -43909,6 +45848,9 @@
xref: Reactome:R-HSA-209823 "Tyrosine is hydroxylated to dopa"
xref: RHEA:18201
is_a: GO:0016714 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.16.2
+property_value: skos:exactMatch RHEA:18201
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004512
@@ -43928,6 +45870,9 @@
xref: Reactome:R-HSA-1855178 "Glc6P is isomerised to I3P by ISYNA1 in the cytosol"
xref: RHEA:10716
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.4
+property_value: skos:exactMatch RHEA:10716
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004513
@@ -43961,6 +45906,9 @@
xref: Reactome:R-HSA-197268 "QPRT transfers PRIB to QUIN to form NAMN"
xref: RHEA:12733
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.19
+property_value: skos:exactMatch RHEA:12733
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004515
@@ -43983,6 +45931,9 @@
xref: Reactome:R-HSA-200512 "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD"
xref: RHEA:22860
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.18
+property_value: skos:exactMatch MetaCyc:NICONUCADENYLYLTRAN-RXN
+property_value: skos:exactMatch RHEA:22860
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29467" xsd:anyURI
[Term]
@@ -44001,6 +45952,8 @@
xref: Reactome:R-HSA-197186 "NAPRT1 dimer transfers PRIB to NCA to form NAMN"
xref: RHEA:36163
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.21
+property_value: skos:exactMatch RHEA:36163
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29467" xsd:anyURI
[Term]
@@ -44022,6 +45975,9 @@
xref: Reactome:R-HSA-418436 "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)"
xref: RHEA:19897
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.39
+property_value: skos:exactMatch RHEA:19897
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004518
@@ -44091,7 +46047,6 @@
xref: Reactome:R-HSA-927836 "SMG6 hydrolyzes mRNA with premature termination codon"
xref: Reactome:R-HSA-9708327 "ANG cleaves tRNA to yield tRNA halves"
xref: Reactome:R-HSA-9708812 "ELAC2 cleaves pre-tRNA to yield 3' trailer (type II tRF or tRF-1)"
-xref: Reactome:R-HSA-9948427 "ANKZF1 cleaves the peptidyl-tRNA in VCP hexamer:LTN1:NEMF:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide"
is_a: GO:0004519 ! endonuclease activity
is_a: GO:0004540 ! RNA nuclease activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
@@ -44117,11 +46072,17 @@
synonym: "S-genotype-assocd. glycoproteins" RELATED []
synonym: "SLSG glycoproteins" RELATED []
xref: EC:4.6.1.18
+xref: MetaCyc:RXN-19932
+xref: MetaCyc:RXN-19933
xref: Wikipedia:Ribonuclease_A
is_a: GO:0004521 ! RNA endonuclease activity
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
+property_value: skos:exactMatch EC:4.6.1.18
+property_value: skos:narrowMatch MetaCyc:RXN-19932
+property_value: skos:narrowMatch MetaCyc:RXN-19933
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004523
@@ -44154,10 +46115,9 @@
xref: Reactome:R-HSA-173769 "RNase H-mediated digestion of tRNA, 3'PPT and cPPT RNA primers"
xref: Reactome:R-HSA-182795 "RNase H-mediated degradation of the template strand"
xref: Reactome:R-HSA-182859 "RNase H-mediated degradation of the RNA strand of the -sssDNA:RNA duplex"
-xref: Reactome:R-HSA-9913637 "RNASEH1 cleaves R-loop RNA to yield RNA primer for H strand polymerization"
-xref: Reactome:R-HSA-9914858 "RNASEH1 cleaves RNA primer from nascent H strand, leaving RNA dinucleotides"
-xref: Reactome:R-HSA-9915449 "RNASEH1 cleaves RNA primer from nascent L strand, leaving RNA dinucleotides"
is_a: GO:0016891 ! RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
+property_value: skos:exactMatch EC:3.1.26.4
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004525
@@ -44177,7 +46137,9 @@
xref: Reactome:R-HSA-9820840 "DICER1 hydrolyzes maternal mRNA:lncRNA to yield endosiRNA"
is_a: GO:0016891 ! RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
is_a: GO:0032296 ! double-stranded RNA-specific ribonuclease activity
+property_value: skos:exactMatch EC:3.1.26.3
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28074" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004526
@@ -44192,6 +46154,8 @@
xref: Wikipedia:RNase_P
is_a: GO:0004549 ! tRNA-specific ribonuclease activity
is_a: GO:0016891 ! RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
+property_value: skos:exactMatch EC:3.1.26.5
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004527
@@ -44227,6 +46191,8 @@
xref: MetaCyc:3.1.4.1-RXN
is_a: GO:0004527 ! exonuclease activity
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.1
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004529
@@ -44264,12 +46230,14 @@
xref: EC:3.1.21.1
xref: MetaCyc:3.1.21.1-RXN
is_a: GO:0016888 ! DNA endonuclease activity, producing 5'-phosphomonoesters
+property_value: skos:exactMatch EC:3.1.21.1
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004531
name: deoxyribonuclease II activity
namespace: molecular_function
-def: "Catalysis of the endonucleolytic cleavage of DNA to 3'-phosphodinucleotide and 3'-phosphooligonucleotide end products." [EC:3.1.22.1]
+def: "Catalysis of the endonucleolytic cleavage of DNA to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products." [EC:3.1.22.1]
synonym: "acid deoxyribonuclease activity" RELATED [EC:3.1.22.1]
synonym: "acid DNase activity" RELATED [EC:3.1.22.1]
synonym: "deoxyribonucleate 3'-nucleotidohydrolase activity" RELATED [EC:3.1.22.1]
@@ -44279,6 +46247,9 @@
xref: EC:3.1.22.1
xref: MetaCyc:3.1.22.1-RXN
is_a: GO:0016889 ! DNA endonuclease activity, producing 3'-phosphomonoesters
+property_value: skos:exactMatch EC:3.1.22.1
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30976" xsd:anyURI
[Term]
id: GO:0004532
@@ -44300,6 +46271,8 @@
xref: EC:3.1.13.2
xref: MetaCyc:3.1.13.2-RXN
is_a: GO:0016896 ! RNA exonuclease activity, producing 5'-phosphomonoesters
+property_value: skos:exactMatch EC:3.1.13.2
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004534
@@ -44308,10 +46281,6 @@
def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule." [GOC:mah, ISBN:0198547684]
synonym: "5'-3' exoribonuclease activity" EXACT []
xref: Reactome:R-HSA-429845 "5' to 3' exoribonuclease hydrolyzes decapped mRNA"
-xref: Reactome:R-HSA-6791227 "47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA"
-xref: Reactome:R-HSA-9915442 "EXOG cleaves RNA dinucleotide from nascent mitochondrial DNA"
-xref: Reactome:R-HSA-9935265 "DXO hydrolyzes uncapped RNA"
-xref: Reactome:R-HSA-9935299 "XRN2 5'-3' exonucleolytically hydrolyzes uncapped RNA"
is_a: GO:0008409 ! 5'-3' exonuclease activity
is_a: GO:0016896 ! RNA exonuclease activity, producing 5'-phosphomonoesters
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28062" xsd:anyURI
@@ -44329,11 +46298,11 @@
xref: Reactome:R-HSA-429955 "CCR4-NOT complex deadenylates mRNA"
xref: Reactome:R-HSA-429992 "PARN deadenylates mRNA"
xref: Reactome:R-HSA-430021 "PAN2-PAN3 complex partially deadenylates mRNA"
-xref: Reactome:R-HSA-9009950 "PDE12 cleaves 2'-5' oligoadenylates"
-xref: Reactome:R-HSA-9615042 "Viral 2',5'-PDE cleaves 2'-5' oligoadenylates"
xref: Reactome:R-HSA-9822311 "CCR4-NOT deadenylates mRNA in CCR4-NOT:BTG4:PABPN1L:mRNP"
xref: Reactome:R-HSA-9822335 "CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA"
is_a: GO:0000175 ! 3'-5'-RNA exonuclease activity
+property_value: skos:exactMatch EC:3.1.13.4
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004536
@@ -44402,6 +46371,8 @@
xref: Reactome:R-HSA-9755013 "NME1,2 hexamers phosphorylate RBV-DP"
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
is_a: GO:0019205 ! nucleobase-containing compound kinase activity
+property_value: skos:exactMatch EC:2.7.4.6
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004551
@@ -44429,7 +46400,10 @@
xref: MetaCyc:OCTANOL-DEHYDROGENASE-RXN
xref: RHEA:24620
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.73
+property_value: skos:exactMatch RHEA:24620
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004553
@@ -44443,6 +46417,8 @@
xref: Reactome:R-HSA-6786652 "CHIT1 hydrolyses CHIT to 3xADGP"
xref: Reactome:R-HSA-9661820 "Bacterial GUSB hydrolyses BDG to BIL"
is_a: GO:0016798 ! hydrolase activity, acting on glycosyl bonds
+property_value: skos:exactMatch EC:3.2.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004555
@@ -44455,6 +46431,9 @@
xref: Reactome:R-HSA-188985 "trehalose + H2O => 2 D-glucose"
xref: RHEA:32675
is_a: GO:0015927 ! trehalase activity
+property_value: skos:exactMatch EC:3.2.1.28
+property_value: skos:exactMatch RHEA:32675
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004556
@@ -44470,9 +46449,17 @@
synonym: "taka-amylase A" RELATED []
xref: EC:3.2.1.1
xref: MetaCyc:ALPHA-AMYL-RXN
+xref: MetaCyc:RXN-1823
+xref: MetaCyc:RXN-1825
+xref: MetaCyc:RXN0-5181
xref: Reactome:R-HSA-188979 "Digestion of linear starch (amylose) by extracellular amylase"
xref: Reactome:R-HSA-191114 "Digestion of branched starch (amylopectin) by extracellular amylase"
is_a: GO:0016160 ! amylase activity
+property_value: skos:exactMatch EC:3.2.1.1
+property_value: skos:exactMatch MetaCyc:ALPHA-AMYL-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-1823
+property_value: skos:narrowMatch MetaCyc:RXN-1825
+property_value: skos:narrowMatch MetaCyc:RXN0-5181
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22621" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -44487,7 +46474,12 @@
xref: MetaCyc:ALPHAGALACTOSID-RXN
xref: Reactome:R-HSA-1605736 "GLA hydrolyzes PSAP(195-273):Gb3Cer:PE"
xref: Reactome:R-HSA-9841189 "GLA hydrolyzes PSAP(195-273):Gal2Cer:PE"
+xref: RHEA:21112
+xref: RHEA:28663
is_a: GO:0015925 ! galactosidase activity
+property_value: skos:exactMatch EC:3.2.1.22
+property_value: skos:narrowMatch RHEA:21112
+property_value: skos:narrowMatch RHEA:28663
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24117" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25227" xsd:anyURI
@@ -44520,7 +46512,9 @@
xref: Reactome:R-HSA-5659899 "Defective SI does not hydrolyze maltotriose"
xref: Reactome:R-HSA-5659922 "Defective SI does not hydrolyze Mal"
is_a: GO:0090599 ! alpha-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.20
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24984" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004559
@@ -44540,6 +46534,8 @@
xref: Reactome:R-HSA-8853686 "MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3"
xref: Reactome:R-HSA-9694656 "Spike trimer glycoside chains are extended"
is_a: GO:0015923 ! mannosidase activity
+property_value: skos:exactMatch EC:3.2.1.24
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004560
@@ -44553,6 +46549,9 @@
xref: Reactome:R-HSA-5693807 "FUCA1 hydrolyses NGP:1,6-GlcNAc"
xref: RHEA:12288
is_a: GO:0015928 ! fucosidase activity
+property_value: skos:exactMatch EC:3.2.1.51
+property_value: skos:exactMatch RHEA:12288
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004561
@@ -44572,6 +46571,8 @@
xref: Reactome:R-HSA-2263496 "Defective NAGLU does not hydrolyse Heparan sulfate chain(4)"
xref: Reactome:R-HSA-9036052 "Defective NAGLU does not hydrolyse heparan chain(2)"
is_a: GO:0015929 ! hexosaminidase activity
+property_value: skos:exactMatch EC:3.2.1.50
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004563
@@ -44594,18 +46595,24 @@
xref: MetaCyc:3.2.1.52-RXN
xref: Reactome:R-HSA-1605595 "bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3"
xref: Reactome:R-HSA-1605632 "bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE"
-xref: Reactome:R-HSA-1638053 "HEXA cleaves the terminal GlcNAc from keratan sulfate"
+xref: Reactome:R-HSA-1638053 "HEXA cleaves the terminal GalNAc from keratan sulfate"
xref: Reactome:R-HSA-2105001 "HEXA cleaves the terminal GalNAc from DS"
-xref: Reactome:R-HSA-2162225 "HEXA cleaves the terminal GlcNAc from small HA fragments"
+xref: Reactome:R-HSA-2162225 "HEXA cleaves the terminal GalNAc from small HA fragments"
+xref: Reactome:R-HSA-3656259 "Defective HEXA does not cleave the terminal GalNAc from DS"
+xref: Reactome:R-HSA-3662344 "Defective HEXB does not cleave the terminal GalNAc from DS"
xref: Reactome:R-HSA-9035976 "Defective HEXA does not cleave the terminall GalNAc from small HA fragments"
+xref: Reactome:R-HSA-9035978 "Defective HEXA does not cleave the terminal GalNAc from keratan sulfate"
xref: Reactome:R-HSA-9035982 "Defective HEXB does not cleave the terminal GalNAc from HA fragments"
+xref: Reactome:R-HSA-9035983 "Defective HEXB does not cleave the terminal GalNAc from keratan sulfate"
xref: Reactome:R-HSA-9638075 "HEXB cleaves the terminal GalNAc from DS"
-xref: Reactome:R-HSA-9638076 "HEXB cleaves the terminal GlcNAc from small HA fragments"
-xref: Reactome:R-HSA-9638078 "HEXB cleaves the terminal GlcNAc from keratan sulfate"
+xref: Reactome:R-HSA-9638076 "HEXB cleaves the terminal GalNAc from small HA fragments"
+xref: Reactome:R-HSA-9638078 "HEXB cleaves the terminal GalNAc from keratan sulfate"
xref: Reactome:R-HSA-9840833 "bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer"
xref: Reactome:R-HSA-9840884 "bHEXA,bHEXS hydrolyze GM2A:SM2"
is_a: GO:0015929 ! hexosaminidase activity
+property_value: skos:exactMatch EC:3.2.1.52
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004564
@@ -44626,6 +46633,8 @@
xref: EC:3.2.1.26
xref: MetaCyc:RXN-9985
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.26
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004565
@@ -44644,12 +46653,15 @@
xref: Reactome:R-HSA-1605624 "Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2"
xref: Reactome:R-HSA-1606312 "GLB1 hydrolyzes SapB/C:LacCer"
xref: Reactome:R-HSA-1630306 "GLB1 hydrolyses a glycosaminoglycan"
-xref: Reactome:R-HSA-1793217 "Unknown endo--galactosidase cleaves keratan chain"
+xref: Reactome:R-HSA-1793217 "Keratan sulfate is cleaved from its proteoglycan by an unknown galactosidase"
xref: Reactome:R-HSA-2090079 "GLB1 hydrolyses linker chain(2)"
xref: Reactome:R-HSA-2265534 "Defective GLB1 does not hydrolyse a glycosaminoglycan"
xref: Reactome:R-HSA-9036061 "Defective GLB1 does not hydrolyse linker chain(2)"
xref: Reactome:R-HSA-9840795 "Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2"
is_a: GO:0015925 ! galactosidase activity
+property_value: skos:exactMatch EC:3.2.1.23
+property_value: skos:exactMatch MetaCyc:3.2.1.23-RXN
+property_value: skos:relatedMatch MetaCyc:BGALACT-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -44665,13 +46677,16 @@
xref: EC:3.2.1.31
xref: MetaCyc:BETA-GLUCURONID-RXN
xref: Reactome:R-HSA-1678854 "GUSB tetramer hydrolyses CS/HS precursor"
-xref: Reactome:R-HSA-2162226 "GUSB tetramer hydrolyzes GlcA-1,3-GlcNAc"
+xref: Reactome:R-HSA-2162226 "GUSB tetramer hydrolyses GlcA-1,3-GlcNAc"
xref: Reactome:R-HSA-2162227 "GUSB tetramer hydrolyses (HA)2"
xref: Reactome:R-HSA-2318373 "Defective GUSB does not hydrolyse (HA)2"
xref: Reactome:R-HSA-9036068 "Defective GUSB does not hydrolyse GlcA-1,3-GlcNAc"
xref: Reactome:R-HSA-9036070 "Defective GUSB does not hydrolyse CS/HS precursor"
xref: RHEA:17633
is_a: GO:0046574 ! glucuronidase activity
+property_value: skos:exactMatch EC:3.2.1.31
+property_value: skos:exactMatch RHEA:17633
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30698" xsd:anyURI
[Term]
@@ -44689,6 +46704,8 @@
xref: MetaCyc:3.2.1.25-RXN
xref: Reactome:R-HSA-8853710 "MANBA hydrolyses GlcNAc:Man"
is_a: GO:0015923 ! mannosidase activity
+property_value: skos:exactMatch EC:3.2.1.25
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004568
@@ -44714,6 +46731,9 @@
xref: Reactome:R-HSA-964759 "Alternative endo-mannosidase I route"
xref: RHEA:54824
is_a: GO:0004559 ! alpha-mannosidase activity
+property_value: skos:exactMatch EC:3.2.1.130
+property_value: skos:exactMatch RHEA:54824
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004571
@@ -44732,6 +46752,8 @@
synonym: "mannosidase I" RELATED [EC:3.2.1.113]
xref: EC:3.2.1.113
xref: KEGG_REACTION:R12479
+xref: MetaCyc:RXN-18910
+xref: MetaCyc:RXN-18911
xref: Reactome:R-HSA-4793949 "Defective MAN1B1 does not hydrolyse 1,2-linked mannose (a branch)"
xref: Reactome:R-HSA-6782685 "EDEM1,3 hydrolyse (GlcNAc)2 (Man)8b to (GlcNAc)2 (Man)5"
xref: Reactome:R-HSA-901024 "MAN1B1 hydrolyses 1,2-linked mannose (a branch)"
@@ -44745,8 +46767,16 @@
xref: Reactome:R-HSA-964825 "Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2"
xref: Reactome:R-HSA-964830 "Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2"
xref: Reactome:R-HSA-9696807 "N-glycan mannose trimming of Spike"
+xref: RHEA:56008
+xref: RHEA:56028
is_a: GO:0015924 ! mannosyl-oligosaccharide mannosidase activity
+property_value: skos:exactMatch EC:3.2.1.113
+property_value: skos:narrowMatch MetaCyc:RXN-18910
+property_value: skos:narrowMatch MetaCyc:RXN-18911
+property_value: skos:narrowMatch RHEA:56008
+property_value: skos:narrowMatch RHEA:56028
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004572
@@ -44770,6 +46800,9 @@
xref: Reactome:R-HSA-975814 "Trimming of mannoses on the alpha1,6 arm by MAN2A1"
xref: RHEA:56052
is_a: GO:0015924 ! mannosyl-oligosaccharide mannosidase activity
+property_value: skos:exactMatch EC:3.2.1.114
+property_value: skos:exactMatch RHEA:56052
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004573
@@ -44786,10 +46819,12 @@
xref: Reactome:R-HSA-4793947 "Defective MOGS does not cleave glucose from an N-glycosylated protein"
xref: Reactome:R-HSA-532678 "Trimming of the first glucose by by mannosyl-oligosaccharide glucosidase"
xref: Reactome:R-HSA-9694364 "N-glycan glucose trimming of Spike"
-xref: Reactome:R-HSA-9932344 "MOGS removes terminal glucose from Glu3Man9GlcNAc2-CDH1"
xref: RHEA:55988
is_a: GO:0090599 ! alpha-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.106
+property_value: skos:exactMatch RHEA:55988
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24984" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004574
@@ -44807,8 +46842,14 @@
synonym: "oligosaccharide alpha-1,6-glucosidase activity" RELATED [EC:3.2.1.10]
synonym: "sucrase-isomaltase activity" RELATED [EC:3.2.1.10]
xref: EC:3.2.1.10
+xref: MetaCyc:3.2.1.10-RXN
+xref: RHEA:68864
is_a: GO:0090599 ! alpha-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.10
+property_value: skos:narrowMatch MetaCyc:3.2.1.10-RXN
+property_value: skos:narrowMatch RHEA:68864
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004575
@@ -44833,6 +46874,9 @@
xref: RHEA:33795
is_a: GO:0004564 ! beta-fructofuranosidase activity
is_a: GO:0090599 ! alpha-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.48
+property_value: skos:exactMatch RHEA:33795
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004576
@@ -44857,6 +46901,9 @@
xref: Reactome:R-HSA-5633241 "Defective ALG14 does not transfer GlcNAc from UDP-GlcNAc to GlcNAcDOLP"
xref: RHEA:23380
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.141
+property_value: skos:exactMatch RHEA:23380
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004578
@@ -44873,6 +46920,9 @@
xref: RHEA:13865
is_a: GO:0019187 ! beta-1,4-mannosyltransferase activity
is_a: GO:0120562 ! GlcNAc(2)-PP-Dol mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.142
+property_value: skos:exactMatch RHEA:13865
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30326" xsd:anyURI
[Term]
@@ -44892,11 +46942,12 @@
xref: MetaCyc:RXN-16761
xref: Reactome:R-HSA-446209 "Transfer of N-glycan to the protein"
xref: Reactome:R-HSA-9694793 "Spike protein gets N-glycosylated"
-xref: Reactome:R-HSA-9816276 "CDH1 is N-glycosylated on asparagine residues in endoplasmic reticulum"
-xref: Reactome:R-HSA-9931286 "CD274 N-linked glycosylation in ER"
xref: RHEA:22980
is_a: GO:0004576 ! oligosaccharyl transferase activity
+property_value: skos:exactMatch EC:2.4.99.18
+property_value: skos:exactMatch RHEA:22980
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26808" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004581
@@ -44917,6 +46968,9 @@
xref: Reactome:R-HSA-446214 "Synthesis of dolichyl-phosphate-glucose"
xref: RHEA:15401
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.117
+property_value: skos:exactMatch RHEA:15401
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004582
@@ -44948,6 +47002,9 @@
xref: Reactome:R-HSA-4719375 "Defective DPM2 does not transfer mannose to DOLP to form DOLPman"
xref: RHEA:21184
is_a: GO:0000030 ! mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.83
+property_value: skos:exactMatch RHEA:21184
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004583
@@ -44999,6 +47056,9 @@
xref: RHEA:19513
is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity
relationship: part_of GO:0006591 ! ornithine metabolic process
+property_value: skos:exactMatch EC:2.1.3.3
+property_value: skos:exactMatch RHEA:19513
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004586
@@ -45014,6 +47074,9 @@
xref: Reactome:R-HSA-70692 "ornithine => putrescine + CO2"
xref: RHEA:22964
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.17
+property_value: skos:exactMatch RHEA:22964
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004587
@@ -45047,6 +47110,9 @@
xref: Reactome:R-HSA-70666 "glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT]"
xref: RHEA:13877
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.13
+property_value: skos:exactMatch MetaCyc:ORNITHINE--OXO-ACID-AMINOTRANSFERASE-RXN
+property_value: skos:exactMatch RHEA:13877
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25975" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -45076,6 +47142,9 @@
xref: Reactome:R-HSA-73567 "UMPS dimer transfers phosphoribosyl group to ORO to form OMP"
xref: RHEA:10380
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.10
+property_value: skos:exactMatch RHEA:10380
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004589
@@ -45090,8 +47159,11 @@
xref: RHEA:13513
is_a: GO:0004152 ! dihydroorotate dehydrogenase activity
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.14
+property_value: skos:exactMatch RHEA:13513
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23786" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004590
@@ -45122,6 +47194,9 @@
xref: Reactome:R-HSA-73564 "UMPS dimer decarboxylates OMP to UMP"
xref: RHEA:11596
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.23
+property_value: skos:exactMatch RHEA:11596
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004591
@@ -45148,6 +47223,13 @@
xref: Reactome:R-HSA-71401 "OGDH dimer decarboxylates 2-OG"
xref: RHEA:12188
is_a: GO:0016624 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
+property_value: skos:broadMatch EC:1.2.1.105
+property_value: skos:broadMatch KEGG_REACTION:R08549
+property_value: skos:broadMatch MetaCyc:2OXOGLUTARATEDEH-RXN
+property_value: skos:broadMatch RHEA:27786
+property_value: skos:exactMatch EC:1.2.4.2
+property_value: skos:exactMatch MetaCyc:2OXOGLUTDECARB-RXN
+property_value: skos:exactMatch RHEA:12188
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25639" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29951" xsd:anyURI
@@ -45165,6 +47247,9 @@
xref: MetaCyc:PANTOATE-BETA-ALANINE-LIG-RXN
xref: RHEA:10912
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.1
+property_value: skos:exactMatch RHEA:10912
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004593
@@ -45179,6 +47264,9 @@
xref: MetaCyc:PANTOTHENASE-RXN
xref: RHEA:12448
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.22
+property_value: skos:exactMatch RHEA:12448
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004594
@@ -45197,6 +47285,9 @@
xref: RHEA:16373
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.33
+property_value: skos:exactMatch RHEA:16373
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004595
@@ -45218,6 +47309,9 @@
xref: Reactome:R-HSA-196754 "COASY transfers an adenylyl group from ATP to PPANT"
xref: RHEA:19801
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.3
+property_value: skos:exactMatch RHEA:19801
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004596
@@ -45238,6 +47332,8 @@
xref: Reactome:R-HSA-6814090 "NatC acetylates ARFFRP1"
xref: RHEA:21028
is_a: GO:0034212 ! protein N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.255
+property_value: skos:exactMatch RHEA:21028
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24761" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27532" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29507" xsd:anyURI
@@ -45259,6 +47355,9 @@
xref: RHEA:20924
is_a: GO:0016842 ! amidine-lyase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:4.3.2.5
+property_value: skos:exactMatch RHEA:20924
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004600
@@ -45279,7 +47378,7 @@
alt_id: GO:0016686
alt_id: GO:0016687
alt_id: GO:0016693
-def: "Catalysis of the reaction: a donor + a peroxide = an oxidized donor + 2 H2O." [GOC:curators]
+def: "Catalysis of the reaction: a reduced substrate + ROOH = an oxidized substrate + ROH + H2O." [PMID:33992367]
subset: goslim_metagenomics
synonym: "bacterial catalase-peroxidase activity" NARROW []
synonym: "donor:hydrogen-peroxide oxidoreductase activity" RELATED []
@@ -45304,9 +47403,14 @@
xref: KEGG_REACTION:R03532
xref: Reactome:R-HSA-1222346 "AhpC reduces H2O2"
xref: Reactome:R-HSA-140359 "PGG2 is reduced to PGH2 by PTGS1"
+xref: Reactome:R-HSA-209815 "Tyrosine is monoiodinated"
+xref: Reactome:R-HSA-209840 "Two DITs combine to form thyroxine"
+xref: Reactome:R-HSA-209925 "DIT and MIT combine to form triiodothyronine"
+xref: Reactome:R-HSA-209973 "Tyrosine is diiodinated"
xref: Reactome:R-HSA-2309773 "PGG2 is reduced to PGH2 by PTGS2"
xref: Reactome:R-HSA-2559639 "Collagen type IV sulfilimine cross-linking by peroxidasin"
xref: Reactome:R-HSA-3341296 "GPX7,8 catalyze peroxidation of P4HB (PDI)"
+xref: Reactome:R-HSA-350901 "Iodide is organified"
xref: Reactome:R-HSA-5631885 "PRDX1 overoxidizes"
xref: Reactome:R-HSA-6789031 "Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl)"
xref: Reactome:R-HSA-6789126 "Myeloperoxidase (MPO) produces hypochlorous acid (HOCl)"
@@ -45315,8 +47419,11 @@
xref: Wikipedia:Peroxidase
is_a: GO:0016209 ! antioxidant activity
is_a: GO:0016684 ! oxidoreductase activity, acting on peroxide as acceptor
+property_value: skos:exactMatch EC:1.11.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23121" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25776" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31239" xsd:anyURI
[Term]
id: GO:0004602
@@ -45343,7 +47450,10 @@
xref: Reactome:R-HSA-71676 "GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O"
xref: RHEA:16833
is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch EC:1.11.1.9
+property_value: skos:exactMatch RHEA:16833
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25498" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004603
@@ -45363,6 +47473,9 @@
xref: RHEA:12176
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.28
+property_value: skos:exactMatch RHEA:12176
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004604
@@ -45385,6 +47498,9 @@
xref: MetaCyc:1.8.4.8-RXN
xref: RHEA:11724
is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
+property_value: skos:exactMatch EC:1.8.4.8
+property_value: skos:exactMatch RHEA:11724
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004605
@@ -45412,6 +47528,9 @@
xref: Reactome:R-HSA-1483165 "PA is converted to CDP-DAG by CDS2"
xref: RHEA:16229
is_a: GO:0070567 ! cytidylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.41
+property_value: skos:exactMatch RHEA:16229
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004607
@@ -45429,6 +47548,9 @@
xref: Reactome:R-HSA-264695 "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)"
xref: RHEA:21204
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.43
+property_value: skos:exactMatch RHEA:21204
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004608
@@ -45449,6 +47571,9 @@
xref: RHEA:11164
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.17
+property_value: skos:exactMatch RHEA:11164
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004609
@@ -45464,6 +47589,9 @@
xref: Reactome:R-HSA-1483212 "PS is decarboxylated to PE by PISD"
xref: RHEA:20828
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.65
+property_value: skos:exactMatch RHEA:20828
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004610
@@ -45482,6 +47610,9 @@
xref: Reactome:R-HSA-446185 "Isomerization of GlcNAc6P to GlcNAc1P"
xref: RHEA:23804
is_a: GO:0016868 ! intramolecular phosphotransferase activity
+property_value: skos:exactMatch EC:5.4.2.3
+property_value: skos:exactMatch RHEA:23804
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004611
@@ -45513,6 +47644,9 @@
xref: MetaCyc:PEPCARBOXYKIN-RXN
xref: RHEA:18617
is_a: GO:0004611 ! phosphoenolpyruvate carboxykinase activity
+property_value: skos:exactMatch EC:4.1.1.49
+property_value: skos:exactMatch RHEA:18617
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004613
@@ -45533,6 +47667,9 @@
xref: Reactome:R-HSA-70241 "PCK1 phosphorylates OA to yield PEP"
xref: RHEA:10388
is_a: GO:0004611 ! phosphoenolpyruvate carboxykinase activity
+property_value: skos:exactMatch EC:4.1.1.32
+property_value: skos:exactMatch RHEA:10388
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004614
@@ -45549,6 +47686,9 @@
xref: Reactome:R-HSA-9638127 "PGM1:Mg2+ isomerises G6P to G1P"
xref: RHEA:23536
is_a: GO:0016868 ! intramolecular phosphotransferase activity
+property_value: skos:exactMatch EC:5.4.2.2
+property_value: skos:exactMatch RHEA:23536
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004615
@@ -45567,6 +47707,9 @@
xref: Reactome:R-HSA-446201 "PMM1,2 isomerise Man6P to Man1P"
xref: RHEA:11140
is_a: GO:0016868 ! intramolecular phosphotransferase activity
+property_value: skos:exactMatch EC:5.4.2.8
+property_value: skos:exactMatch RHEA:11140
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004616
@@ -45582,10 +47725,13 @@
synonym: "phosphogluconic acid dehydrogenase activity" RELATED [EC:1.1.1.44]
xref: EC:1.1.1.44
xref: MetaCyc:RXN-9952
-xref: Reactome:R-HSA-71299 "PGD decarboxylates 6-phospho-D-gluconate"
+xref: Reactome:R-HSA-71299 "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+"
xref: RHEA:10116
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.44
+property_value: skos:exactMatch RHEA:10116
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25816" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004617
@@ -45615,6 +47761,9 @@
xref: Reactome:R-HSA-977348 "PHGDH tetramer dehydrogenates 3PG"
xref: RHEA:12641
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.95
+property_value: skos:exactMatch RHEA:12641
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004618
@@ -45640,10 +47789,13 @@
xref: KEGG_REACTION:R01512
xref: MetaCyc:PHOSGLYPHOS-RXN
xref: Reactome:R-HSA-70486 "PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG"
-xref: Reactome:R-HSA-71850 "PGK complexes dephosphorylate 1,3BPG"
+xref: Reactome:R-HSA-71850 "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP"
xref: RHEA:14801
is_a: GO:0016301 ! kinase activity
is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor
+property_value: skos:exactMatch EC:2.7.2.3
+property_value: skos:exactMatch RHEA:14801
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004619
@@ -45658,45 +47810,57 @@
synonym: "PGM" EXACT []
synonym: "phosphoglycerate phosphomutase activity" RELATED []
synonym: "phosphoglyceromutase activity" RELATED []
+xref: EC:5.4.2.11
+xref: EC:5.4.2.12
xref: KEGG_REACTION:R01516
-xref: Reactome:R-HSA-71445 "PGAM dimers isomerise 2PG to 3PG"
-xref: Reactome:R-HSA-71654 "PGAM dimers isomerise 3PG to 2PG"
+xref: MetaCyc:3PGAREARR-RXN
+xref: MetaCyc:RXN-15513
+xref: Reactome:R-HSA-71445 "PGAM dimers (PGAM1,2) isomerise 2PG to 3PG"
+xref: Reactome:R-HSA-71654 "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate"
xref: RHEA:15901
is_a: GO:0016868 ! intramolecular phosphotransferase activity
+property_value: skos:exactMatch RHEA:15901
+property_value: skos:narrowMatch EC:5.4.2.11
+property_value: skos:narrowMatch EC:5.4.2.12
+property_value: skos:narrowMatch MetaCyc:3PGAREARR-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-15513
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24905" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25780" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004620
-name: phospholipase activity
+name: glycerophospholipase activity
namespace: molecular_function
-def: "Catalysis of the hydrolysis of a glycerophospholipid." [ISBN:0198506732]
+def: "Catalysis of the hydrolysis of a glycerophospholipid." [PMID:30109646]
subset: goslim_chembl
+synonym: "glycerophospholipid hydrolase activity" EXACT []
+synonym: "phospholipase activity" RELATED []
xref: Reactome:R-HSA-6786650 "DDHD1,2 hydrolyse PA"
xref: Reactome:R-HSA-6792445 "LIPH, I hydrolyse PA to 2-acyl LPA"
-is_a: GO:0016298 ! lipase activity
+is_a: GO:0120569 ! phospholipase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21843" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30258" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31030" xsd:anyURI
[Term]
id: GO:0004621
-name: glycosylphosphatidylinositol phospholipase D activity
+name: GPI anchor phospholipase D activity
namespace: molecular_function
-def: "Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol." [EC:3.1.4.50]
-synonym: "glycoprotein phospholipase D activity" EXACT []
-synonym: "glycoprotein-phosphatidylinositol phosphatidohydrolase activity" RELATED [EC:3.1.4.50]
-synonym: "GPI-PLD activity" RELATED [EC:3.1.4.50]
-synonym: "phosphatidylinositol phospholipase D activity" RELATED [EC:3.1.4.50]
-synonym: "phosphatidylinositol-glycan-specific phospholipase D activity" RELATED [EC:3.1.4.50]
-synonym: "phosphatidylinositol-specific phospholipase D activity" RELATED [EC:3.1.4.50]
-xref: EC:3.1.4.50
-xref: MetaCyc:GLYCOPROTEIN-PHOSPHOLIPASE-D-RXN
+def: "Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol, by cleavage of the second phosphodiester bond between the phosphate and phospholipid." [PMID:2760042]
+synonym: "glycoprotein phospholipase D activity" BROAD []
+synonym: "glycoprotein-phosphatidylinositol phosphatidohydrolase activity" EXACT []
+synonym: "glycosylphosphatidyl inositol-anchor protein phospholipase D activity" EXACT []
+synonym: "GPI-PLD activity" EXACT []
xref: Reactome:R-HSA-8940388 "GPLD1 hydrolyses GPI-anchors from proteins"
-xref: RHEA:10832
-is_a: GO:0004630 ! phospholipase D activity
+is_a: GO:0004630 ! D-type glycerophospholipase activity
+property_value: skos:broadMatch EC:3.1.4.50
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28868" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31078" xsd:anyURI
[Term]
id: GO:0004622
-name: phosphatidylcholine lysophospholipase activity
+name: phosphatidylcholine lysophospholipase A1 activity
namespace: molecular_function
alt_id: GO:0045126
def: "Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphocholine + H2O = a fatty acid + H+ + sn-glycerol 3-phosphocholine." [RHEA:15177]
@@ -45711,6 +47875,7 @@
synonym: "lysophospholipase A1" RELATED [EC:3.1.1.5]
synonym: "lysophospholipase activity" BROAD [EC:3.1.1.5]
synonym: "phosphatidase B" RELATED [EC:3.1.1.5]
+synonym: "phosphatidylcholine lysophospholipase A1-type activity" EXACT []
synonym: "phospholipase B activity" RELATED [EC:3.1.1.5]
xref: EC:3.1.1.5
xref: MetaCyc:LYSOPHOSPHOLIPASE-RXN
@@ -45725,29 +47890,33 @@
xref: Reactome:R-HSA-6814778 "GDPD3 hydrolyzes LysoPtdCho"
xref: Reactome:R-HSA-8847912 "PNPLA7 hydrolyzes LysoPtdCho"
xref: RHEA:15177
-is_a: GO:0120558 ! lysophospholipase activity
+is_a: GO:0120558 ! lysophospholipase A1 activity
+property_value: skos:exactMatch EC:3.1.1.5
+property_value: skos:exactMatch RHEA:15177
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27557" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28339" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30258" xsd:anyURI
[Term]
id: GO:0004623
-name: phospholipase A2 activity
+name: A2-type glycerophospholipase activity
namespace: molecular_function
alt_id: GO:0102567
alt_id: GO:0102568
-def: "Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = 1-acyl-sn-glycero-3-phospholipid + a fatty acid. This reaction removes the fatty acid attached to the sn2-position. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides." [RHEA:15801]
+def: "A glycerophospholipase activity that cleaves the fatty acid attached to the sn-2 position of the glycerol group of a glycerophospholipid. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides." [PMID:30109646]
subset: goslim_chembl
synonym: "cytosolic phospholipase A2 activity" NARROW []
synonym: "lecithinase A activity" RELATED [EC:3.1.1.4]
synonym: "phosphatidase activity" RELATED [EC:3.1.1.4]
synonym: "phosphatidolipase activity" RELATED [EC:3.1.1.4]
synonym: "phosphatidylcholine 2-acylhydrolase activity" RELATED [EC:3.1.1.4]
+synonym: "phospholipase A2 activity" EXACT []
synonym: "phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)" NARROW []
synonym: "phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" NARROW []
synonym: "secreted phospholipase A2 activity" NARROW []
xref: EC:3.1.1.4
xref: MetaCyc:PHOSPHOLIPASE-A2-RXN
+xref: MetaCyc:RXN-15065
xref: MetaCyc:RXN-15067
xref: Reactome:R-HSA-1482604 "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)"
xref: Reactome:R-HSA-1482656 "PA is hydrolysed to 1-acyl LPA by PLA2[1]"
@@ -45775,10 +47944,16 @@
xref: Reactome:R-HSA-1602446 "PA is hydrolyzed to 1-acyl LPA by PLA2[15]"
xref: Reactome:R-HSA-8848484 "PLA2s hydrolyze phospholipids at the Golgi membrane"
xref: RHEA:15801
-is_a: GO:0004620 ! phospholipase activity
+is_a: GO:0004620 ! glycerophospholipase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.4
+property_value: skos:narrowMatch MetaCyc:RXN-15065
+property_value: skos:narrowMatch RHEA:15801
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21259" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28339" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30258" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31049" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31198" xsd:anyURI
[Term]
id: GO:0004624
@@ -45799,8 +47974,8 @@
comment: This term was made obsolete because it represents component and function information.
synonym: "calcium-dependent secreted phospholipase A2 activity" EXACT []
is_obsolete: true
+consider: GO:0004623
consider: GO:0005576
-consider: GO:0047498
[Term]
id: GO:0004626
@@ -45821,8 +47996,8 @@
comment: This term was made obsolete because it represents component and function information.
synonym: "calcium-dependent cytosolic phospholipase A2 activity" EXACT []
is_obsolete: true
+consider: GO:0004623
consider: GO:0005829
-consider: GO:0047498
[Term]
id: GO:0004628
@@ -45832,44 +48007,55 @@
comment: This term was made obsolete because it represents component and function information.
synonym: "calcium-independent cytosolic phospholipase A2 activity" EXACT []
is_obsolete: true
+consider: GO:0004623
consider: GO:0005829
-consider: GO:0047499
[Term]
id: GO:0004629
-name: phospholipase C activity
+name: C-type glycerophospholipase activity
namespace: molecular_function
alt_id: GO:0042298
-def: "Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate." [GOC:mah]
+def: "A glycerophospholipase activity that cleaves the first phosphodiester bond between the phosphate and glycerol, producing a mono- or a diacylglycerol, depending on whether the substrate is a lysoglycerophospholipid or a glycerophospholipid." [PMID:30109646]
+synonym: "C-type phospholipase activity" EXACT []
synonym: "phosphatidase C" RELATED []
+synonym: "phospholipase C activity" EXACT []
xref: Reactome:R-HSA-1112666 "BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate"
xref: Reactome:R-HSA-114688 "PLC-beta hydrolyses PIP2 to DAG and IP3"
xref: Reactome:R-HSA-114689 "PLC gamma 2-mediated PIP2 hydrolysis"
xref: Reactome:R-HSA-398193 "PLC beta-mediated PIP2 hydrolysis"
xref: Reactome:R-HSA-399998 "Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate"
xref: Reactome:R-HSA-5362553 "NOTUM releases Hh-Np:GPC5 from the plasma membrane"
-is_a: GO:0004620 ! phospholipase activity
+is_a: GO:0004620 ! glycerophospholipase activity
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:broadMatch EC:3.1.4.3
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23316" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31049" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31078" xsd:anyURI
[Term]
id: GO:0004630
-name: phospholipase D activity
+name: D-type glycerophospholipase activity
namespace: molecular_function
-def: "Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate." [EC:3.1.4.4]
+def: "A glycerophospholipase activity that cleaves the second phosphodiester bond between the phosphate and phospholipid, releasing a phosphatidic acid." [PMID:30109646]
subset: goslim_chembl
synonym: "choline phosphatase activity" RELATED [EC:3.1.4.4]
+synonym: "D-type phospholipase activity" EXACT []
synonym: "lecithinase D activity" RELATED [EC:3.1.4.4]
synonym: "lipophosphodiesterase II activity" RELATED [EC:3.1.4.4]
synonym: "phosphatidylcholine phosphatidohydrolase activity" RELATED [EC:3.1.4.4]
+synonym: "phospholipase D activity" EXACT []
xref: EC:3.1.4.4
xref: MetaCyc:PHOSCHOL-RXN
xref: Reactome:R-HSA-1483142 "PC is transphosphatidylated to PG by PLD1-4/6"
xref: Reactome:R-HSA-1483182 "PC is hydrolyzed to PA and choline by PLD1/2"
xref: Reactome:R-HSA-2029471 "Hydrolysis of PC to PA by PLD"
xref: RHEA:14445
-is_a: GO:0004620 ! phospholipase activity
+is_a: GO:0004620 ! glycerophospholipase activity
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.4
+property_value: skos:narrowMatch RHEA:14445
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31049" xsd:anyURI
[Term]
id: GO:0004631
@@ -45889,6 +48075,9 @@
xref: RHEA:16341
is_a: GO:0016301 ! kinase activity
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
+property_value: skos:exactMatch EC:2.7.4.2
+property_value: skos:exactMatch RHEA:16341
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004632
@@ -45903,6 +48092,9 @@
xref: Reactome:R-HSA-196753 "2xPPCS ligates PPanK with Cys"
xref: RHEA:19397
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.5
+property_value: skos:exactMatch RHEA:19397
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004633
@@ -45921,6 +48113,9 @@
xref: Reactome:R-HSA-196840 "3xPPCDC:3FMN decarboxylates PPC"
xref: RHEA:16793
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.36
+property_value: skos:exactMatch RHEA:16793
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004634
@@ -45941,9 +48136,12 @@
xref: EC:4.2.1.11
xref: MetaCyc:2PGADEHYDRAT-RXN
xref: Reactome:R-HSA-70494 "Enolase dimers (ENO1,2,3) convert PEP to 2PG"
-xref: Reactome:R-HSA-71660 "Enolase dimers dehydrates 2PG"
+xref: Reactome:R-HSA-71660 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O"
xref: RHEA:10164
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.11
+property_value: skos:exactMatch RHEA:10164
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004635
@@ -45958,6 +48156,9 @@
xref: MetaCyc:HISTCYCLOHYD-RXN
xref: RHEA:20049
is_a: GO:0019238 ! cyclohydrolase activity
+property_value: skos:exactMatch EC:3.5.4.19
+property_value: skos:exactMatch RHEA:20049
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004636
@@ -45972,6 +48173,9 @@
xref: MetaCyc:HISTPRATPHYD-RXN
xref: RHEA:22828
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.31
+property_value: skos:exactMatch RHEA:22828
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004637
@@ -45994,6 +48198,9 @@
xref: Reactome:R-HSA-73814 "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi"
xref: RHEA:17453
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.13
+property_value: skos:exactMatch RHEA:17453
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004638
@@ -46014,6 +48221,9 @@
xref: Reactome:R-HSA-73806 "AIR + CO2 => CAIR"
xref: RHEA:10792
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.21
+property_value: skos:exactMatch RHEA:10792
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004639
@@ -46038,6 +48248,9 @@
xref: Reactome:R-HSA-73805 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi"
xref: RHEA:22628
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.6
+property_value: skos:exactMatch RHEA:22628
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004640
@@ -46055,6 +48268,9 @@
xref: MetaCyc:PRAISOM-RXN
xref: RHEA:21540
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.24
+property_value: skos:exactMatch RHEA:21540
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004641
@@ -46075,6 +48291,9 @@
xref: Reactome:R-HSA-73810 "FGAM + ATP => AIR + ADP + Pi"
xref: RHEA:23032
is_a: GO:0016882 ! cyclo-ligase activity
+property_value: skos:exactMatch EC:6.3.3.1
+property_value: skos:exactMatch RHEA:23032
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004642
@@ -46098,6 +48317,9 @@
xref: Reactome:R-HSA-73812 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi"
xref: RHEA:17129
is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor
+property_value: skos:exactMatch EC:6.3.5.3
+property_value: skos:exactMatch RHEA:17129
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004643
@@ -46118,6 +48340,9 @@
xref: Reactome:R-HSA-73798 "AICAR + 10-Formyl-THF => FAICAR + THF"
xref: RHEA:22192
is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity
+property_value: skos:exactMatch EC:2.1.2.3
+property_value: skos:exactMatch RHEA:22192
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004644
@@ -46138,6 +48363,9 @@
xref: Reactome:R-HSA-73813 "GAR + 10-Formyl-THF => FGAR + THF"
xref: RHEA:15053
is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity
+property_value: skos:exactMatch EC:2.1.2.2
+property_value: skos:exactMatch RHEA:15053
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004645
@@ -46162,6 +48390,8 @@
xref: MetaCyc:RXN0-5184
xref: RHEA:41732
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.1
+property_value: skos:exactMatch RHEA:41732
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -46187,6 +48417,9 @@
xref: Reactome:R-HSA-977333 "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA"
xref: RHEA:14329
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.52
+property_value: skos:exactMatch RHEA:14329
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004649
@@ -46199,6 +48432,9 @@
xref: Reactome:R-HSA-8952903 "ADPRHL2 hydrolyses poly(ADP-ribose)"
xref: RHEA:52216
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.143
+property_value: skos:exactMatch RHEA:52216
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004650
@@ -46219,6 +48455,8 @@
xref: EC:3.2.1.15
xref: MetaCyc:RXN-2103
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.15
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004651
@@ -46231,9 +48469,15 @@
xref: EC:3.1.3.33
xref: MetaCyc:RXN-21861
xref: Reactome:R-HSA-77078 "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme"
+xref: RHEA:67772
+xref: RHEA:67776
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.33
+property_value: skos:narrowMatch RHEA:67772
+property_value: skos:narrowMatch RHEA:67776
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25810" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26595" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004652
@@ -46293,6 +48537,8 @@
xref: Reactome:R-HSA-9694438 "GalNAc is transferred onto 3a"
is_a: GO:0008376 ! acetylgalactosaminyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.4.1.41
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004654
@@ -46307,6 +48553,9 @@
xref: MetaCyc:2.7.7.8-RXN
xref: RHEA:22096
is_a: GO:0016779 ! nucleotidyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.8
+property_value: skos:exactMatch RHEA:22096
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004655
@@ -46328,6 +48577,9 @@
xref: Reactome:R-HSA-189439 "ALAD condenses 2 dALAs to form PBG"
xref: RHEA:24064
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.24
+property_value: skos:exactMatch RHEA:24064
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004656
@@ -46360,6 +48612,9 @@
xref: RHEA:18945
is_a: GO:0019798 ! procollagen-proline dioxygenase activity
is_a: GO:0031545 ! peptidyl-proline 4-dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.2
+property_value: skos:exactMatch RHEA:18945
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004657
@@ -46371,9 +48626,12 @@
xref: EC:1.5.5.2
xref: MetaCyc:RXN-14903
xref: Reactome:R-HSA-6784224 "PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate"
-xref: Reactome:R-HSA-8955817 "PRODH2 oxidises HPRO to 1PYR-3OH-5COOH"
+xref: Reactome:R-HSA-70670 "PRODH oxidises L-Pro to 1PYR-5COOH"
+xref: Reactome:R-HSA-8955817 "PRODH2 oxidises HPRO to 1PYR-5COOH"
xref: RHEA:23784
is_a: GO:0016649 ! oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.5.5.2
+property_value: skos:exactMatch RHEA:23784
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23335" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29588" xsd:anyURI
@@ -46390,6 +48648,9 @@
xref: Reactome:R-HSA-71031 "propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate"
xref: RHEA:23720
is_a: GO:0016421 ! CoA carboxylase activity
+property_value: skos:exactMatch EC:6.4.1.3
+property_value: skos:exactMatch RHEA:23720
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004659
@@ -46398,6 +48659,7 @@
def: "Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor)." [GOC:mah]
xref: Reactome:R-HSA-6806674 "UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone)"
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:broadMatch EC:2.5.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25785" xsd:anyURI
[Term]
@@ -46417,6 +48679,8 @@
xref: Reactome:R-HSA-9647978 "pro-RAS proteins are farnesylated"
xref: RHEA:13345
is_a: GO:0008318 ! protein prenyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.58
+property_value: skos:exactMatch RHEA:13345
[Term]
id: GO:0004661
@@ -46427,7 +48691,9 @@
synonym: "protein-cysteine geranylgeranyltransferase activity" EXACT []
xref: RHEA:21240
is_a: GO:0008318 ! protein prenyltransferase activity
+property_value: skos:exactMatch RHEA:21240
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26829" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004662
@@ -46443,7 +48709,9 @@
xref: EC:2.5.1.59
xref: MetaCyc:RXN-3701
is_a: GO:0004661 ! protein geranylgeranyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.59
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25798" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004663
@@ -46458,7 +48726,14 @@
synonym: "RabGGTase activity" EXACT []
synonym: "type II protein geranyl-geranyltransferase activity" RELATED [EC:2.5.1.60]
xref: EC:2.5.1.60
+xref: MetaCyc:RXN-19995
+xref: MetaCyc:RXN-19996
+xref: MetaCyc:RXN-19997
is_a: GO:0004661 ! protein geranylgeranyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.60
+property_value: skos:narrowMatch MetaCyc:RXN-19995
+property_value: skos:narrowMatch MetaCyc:RXN-19996
+property_value: skos:narrowMatch MetaCyc:RXN-19997
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25798" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -46473,6 +48748,9 @@
xref: MetaCyc:PREPHENATEDEHYDRAT-RXN
xref: RHEA:21648
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.51
+property_value: skos:exactMatch RHEA:21648
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004665
@@ -46486,6 +48764,9 @@
xref: MetaCyc:PREPHENATE-DEHYDROGENASE-NADP+-RXN
xref: RHEA:21640
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.13
+property_value: skos:exactMatch RHEA:21640
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004666
@@ -46506,6 +48787,9 @@
xref: Reactome:R-HSA-2309787 "Arachidonate is oxidised to PGG2 by PTGS2"
xref: RHEA:23728
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.1
+property_value: skos:exactMatch RHEA:23728
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004667
@@ -46525,6 +48809,9 @@
xref: Reactome:R-HSA-2161701 "PGH2 is isomerised to PGD2 by HPGDS"
xref: RHEA:10600
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:exactMatch EC:5.3.99.2
+property_value: skos:exactMatch RHEA:10600
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004668
@@ -46539,7 +48826,10 @@
xref: Reactome:R-HSA-3247569 "PADI4 deiminates Histones"
xref: RHEA:18089
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.15
+property_value: skos:exactMatch RHEA:18089
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18666" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004671
@@ -46571,6 +48861,9 @@
xref: RHEA:21672
is_a: GO:0003880 ! protein C-terminal carboxyl O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.100
+property_value: skos:exactMatch RHEA:21672
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004672
@@ -46582,7 +48875,6 @@
subset: goslim_candida
synonym: "protamine kinase activity" NARROW []
xref: Reactome:R-HSA-156832 "INF-gamma induced phosphorylation of L13a"
-xref: Reactome:R-HSA-5693148 "BCKDK phosphorylates BCKDH"
xref: Reactome:R-HSA-937034 "IRAK1 phosphorylates Pellino"
xref: Reactome:R-HSA-9604606 "Unknown kinase phosphorylates NICD4"
xref: Reactome:R-HSA-9673284 "GTP-bound RAC1 contributes to MAPK8 activation"
@@ -46621,6 +48913,8 @@
is_a: GO:0004672 ! protein kinase activity
is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor
relationship: part_of GO:0018106 ! peptidyl-histidine phosphorylation
+property_value: skos:exactMatch EC:2.7.13.3
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004674
@@ -46642,6 +48936,11 @@
synonym: "serine/threonine protein kinase activity" RELATED [EC:2.7.11.1]
synonym: "threonine-specific protein kinase activity" NARROW [EC:2.7.11.1]
xref: EC:2.7.11.-
+xref: EC:2.7.11.1
+xref: EC:2.7.11.28
+xref: EC:2.7.11.29
+xref: EC:2.7.11.3
+xref: EC:2.7.11.9
xref: MetaCyc:PROTEIN-KINASE-RXN
xref: Reactome:R-HSA-109702 "PDPK1 phosphorylates AKT2"
xref: Reactome:R-HSA-109822 "MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1"
@@ -46700,9 +48999,9 @@
xref: Reactome:R-HSA-168140 "Active IKK Complex phosphorylates NF-kappa-B inhibitor"
xref: Reactome:R-HSA-168184 "Activated TAK1 mediates phosphorylation of the IKK Complex"
xref: Reactome:R-HSA-170055 "Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes"
-xref: Reactome:R-HSA-170076 "CAK phosphorylates CDK1 bound to CCNB1"
-xref: Reactome:R-HSA-170087 "CAK phosphorylates CDK1 bound to CCNA"
-xref: Reactome:R-HSA-170116 "PKMYT1 phosphorylates CCNA:CDK1"
+xref: Reactome:R-HSA-170076 "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes"
+xref: Reactome:R-HSA-170087 "CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes"
+xref: Reactome:R-HSA-170116 "Myt-1 mediated phosphorylation of Cyclin A:Cdc2"
xref: Reactome:R-HSA-170126 "Phosphorylation of Cyclin B1 in the CRS domain"
xref: Reactome:R-HSA-170977 "FRS2 is phosphorylated by active TrkA receptor"
xref: Reactome:R-HSA-174119 "Free APC/C phosphorylated by Plk1"
@@ -46713,7 +49012,6 @@
xref: Reactome:R-HSA-187949 "CAK-mediated phosphorylation of Cyclin A:Cdk2"
xref: Reactome:R-HSA-188350 "CAK-mediated phosphorylation of Cyclin E:Cdk2"
xref: Reactome:R-HSA-193647 "IRAK is activated"
-xref: Reactome:R-HSA-193703 "IKKbeta is activated"
xref: Reactome:R-HSA-193705 "IKKbeta phosphorylates IkB causing NF-kB to dissociate"
xref: Reactome:R-HSA-195275 "Phosphorylation of APC component of the destruction complex"
xref: Reactome:R-HSA-195283 "Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3"
@@ -46852,6 +49150,7 @@
xref: Reactome:R-HSA-399951 "Phosphorylation of CRMPs by GSK3beta"
xref: Reactome:R-HSA-399952 "Phosphorylation of LIMK-1 by PAK"
xref: Reactome:R-HSA-399978 "Protein kinase C, alpha type phosphorylates MARCKS"
+xref: Reactome:R-HSA-400382 "CSNK1E,CSNK1D phosphorylate CRY and PER proteins"
xref: Reactome:R-HSA-4088134 "PLK1 phosphorylates FOXM1"
xref: Reactome:R-HSA-419083 "Myosin phosphatase inactivation by ROCK"
xref: Reactome:R-HSA-419087 "LIM kinase phosphorylation by ROCK"
@@ -46912,10 +49211,8 @@
xref: Reactome:R-HSA-5610722 "CK1 phosphorylates p-GLI3"
xref: Reactome:R-HSA-5610730 "GSK3 phosphorylates p-GLI2"
xref: Reactome:R-HSA-5610732 "GSK3 phosphorylates p-GLI3"
-xref: Reactome:R-HSA-5623667 "PDPK1 phosphorylates PKN1,2,3"
xref: Reactome:R-HSA-5624473 "Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit"
xref: Reactome:R-HSA-5624492 "PAK phosphorylates p21 RAF1 on S338"
-xref: Reactome:R-HSA-5625784 "PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters"
xref: Reactome:R-HSA-5627775 "Autophosphorylation of PAK1,2,3"
xref: Reactome:R-HSA-5632670 "CSNK1A1 phosphorylates SMO dimer"
xref: Reactome:R-HSA-5632672 "ADRBK1 phosphorylates SMO dimer"
@@ -46928,7 +49225,6 @@
xref: Reactome:R-HSA-5668947 "PAK1 phosphorylates myosin phosphatase"
xref: Reactome:R-HSA-5668984 "PAK1 or PAK2 phosphorylates MYLK"
xref: Reactome:R-HSA-5669250 "PAK1 phosphorylates FLNA"
-xref: Reactome:R-HSA-5671749 "p-T774-PKN1 phosphorylates CDC25C"
xref: Reactome:R-HSA-5671763 "p-T774-PKN1 phosphorylates PPP1R14A"
xref: Reactome:R-HSA-5671919 "Activated CIT phosphorylates MRLCs"
xref: Reactome:R-HSA-5672008 "Thr-180 of ULK1 is phosphorylated"
@@ -47011,8 +49307,8 @@
xref: Reactome:R-HSA-6810233 "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter"
xref: Reactome:R-HSA-6811454 "MAPKs phosphorylate PP2A"
xref: Reactome:R-HSA-6814409 "CK2 phosphorylates PDCL"
-xref: Reactome:R-HSA-69604 "Phosphorylation of CDC25A by CHEK1"
-xref: Reactome:R-HSA-69608 "Phosphorylation of CDC25A by CHEK2"
+xref: Reactome:R-HSA-69604 "Phosphorylation of Cdc25A at Ser-123 by Chk1"
+xref: Reactome:R-HSA-69608 "Phosphorylation of Cdc25A at Ser-123 by Chk2"
xref: Reactome:R-HSA-69685 "CHEK2 phosphorylates TP53"
xref: Reactome:R-HSA-69891 "Phosphorylation and activation of CHEK2 by ATM"
xref: Reactome:R-HSA-75010 "Phosphorylation of Cdc25C at Ser 216 by Chk1"
@@ -47060,7 +49356,6 @@
xref: Reactome:R-HSA-9009208 "Activated ERKs phosphorylate RUNX2"
xref: Reactome:R-HSA-9012319 "p-TEFb phosphorylates serine 2 in RNA polymerase II CTD"
xref: Reactome:R-HSA-9013978 "Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex"
-xref: Reactome:R-HSA-9021357 "PRKCI phosphorylates ELF3"
xref: Reactome:R-HSA-9022314 "HIPK2 phosphorylates MECP2"
xref: Reactome:R-HSA-9023132 "AURKB phosphorylates MECP2 at S423"
xref: Reactome:R-HSA-9032751 "Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3"
@@ -47068,7 +49363,6 @@
xref: Reactome:R-HSA-912470 "ATR phosphorylates Histone H2A.X at unsynapsed regions"
xref: Reactome:R-HSA-913996 "PKA/PKG phosphorylate Rap1GAP2"
xref: Reactome:R-HSA-918229 "Phosphorylation and release of IRF3/IRF7"
-xref: Reactome:R-HSA-927889 "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)"
xref: Reactome:R-HSA-933525 "Phosphorylation and release of IRF7"
xref: Reactome:R-HSA-934559 "SPRY2 is phosphorylated by phosphorylated MNK1"
xref: Reactome:R-HSA-936951 "Activation of TAK1 complex bound to activated TLR4 complex"
@@ -47088,7 +49382,6 @@
xref: Reactome:R-HSA-9624526 "AKT phosphorylates FOXO3 downstream of ESR1 and EGFR"
xref: Reactome:R-HSA-9626880 "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345"
xref: Reactome:R-HSA-9627089 "CASP9 is phosphorylated at T412"
-xref: Reactome:R-HSA-9632858 "PRKCZ autophosphorylates downstream of estrogen stimulation"
xref: Reactome:R-HSA-9632868 "CDKN1B is phosphorylated in response to estrogen"
xref: Reactome:R-HSA-9633008 "p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1"
xref: Reactome:R-HSA-9633742 "EIF2AK4 (GCN2) dimer autophosphorylates"
@@ -47125,11 +49418,9 @@
xref: Reactome:R-HSA-975874 "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex"
xref: Reactome:R-HSA-975878 "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR"
xref: Reactome:R-HSA-9762094 "GSK3B phosphorylates p-NFE2L2"
-xref: Reactome:R-HSA-9765960 "ERKs phosphorylate MCRIP1"
xref: Reactome:R-HSA-9766532 "SQSTM1 oligomer is phosphorylated"
xref: Reactome:R-HSA-9769115 "MAPK1,(MAPK3) phosphorylates NPAS4"
xref: Reactome:R-HSA-9773803 "Active IKBKB phosphorylates NF-kappa-B inhibitor"
-xref: Reactome:R-HSA-9796053 "PRKCI phosphorylates NFE2L2"
xref: Reactome:R-HSA-9796067 "PRKAA2 phosphorylates nuclear NFE2L2"
xref: Reactome:R-HSA-9796081 "EIF2AK3 phosphorylates NFE2L2"
xref: Reactome:R-HSA-9815501 "MAPKAPK2 phosphorylates RIPK1 at S320"
@@ -47153,31 +49444,18 @@
xref: Reactome:R-HSA-9851972 "PLK1 phosphorylates FIRRM at S43"
xref: Reactome:R-HSA-9853369 "PLK1 phosphorylates FIRMM at S744"
xref: Reactome:R-HSA-9855910 "USF1 is phosphorylated by p-MAPK14"
-xref: Reactome:R-HSA-9857661 "p-T308,S473-AKT1 (phospho-PKB) phosphorylates GJA1 (Connexin-43)"
-xref: Reactome:R-HSA-9857673 "p-T308,S473-AKT1 phosphorylates ITGA5 (Integrin alpha5) in ITGA5:ITGB1 (Integrin alpha5:Integrin beta1)"
xref: Reactome:R-HSA-9860292 "Activated IKBKB phosphorylates IRF5"
xref: Reactome:R-HSA-9860785 "PDPK1 (PDK1) phosphorylates PKN2 on threonine-816"
xref: Reactome:R-HSA-9860800 "mTORC2 phosphorylates AKT1 on serine-473"
xref: Reactome:R-HSA-9861642 "NEK1 phosphorylates ME1"
-xref: Reactome:R-HSA-9909369 "CSNK1E,CSNK1D phosphorylate CRY and PER proteins"
-xref: Reactome:R-HSA-9912396 "CDK5 phosphorylates CLOCK on serine-451 and serine-461"
-xref: Reactome:R-HSA-9912401 "CK2alpha phosphorylates BMAL1 (ARNTL) on serine-90"
-xref: Reactome:R-HSA-9920673 "CDK5 phosphorylates PER2 on serine-396"
-xref: Reactome:R-HSA-9922273 "CSNK1D,E phosphorylates CLOCK in p-S-CRY:p-S-PER:CSNK1D,E:p-S90,Ac-538-BMAL:p-2T,3S-CLOCK:target gene"
-xref: Reactome:R-HSA-9926483 "MARK3 phosphorylates MITF-M on S173"
-xref: Reactome:R-HSA-9929360 "GSK3B phosphorylates CD274"
-xref: Reactome:R-HSA-9931292 "AMPK phosphorylates CD274"
-xref: Reactome:R-HSA-9931409 "NEK2 phosphorylates CD274"
-xref: Reactome:R-HSA-9931418 "CK2 phosphorylates CD274"
-xref: Reactome:R-HSA-9933380 "Cytosolic tail of CDH1 is phosphorylated"
-xref: Reactome:R-HSA-9942578 "Phosphorylation of CDC25A by p38 MAPK"
-xref: Reactome:R-HSA-9943662 "CHEK1 phosphorylates NEK11"
-xref: Reactome:R-HSA-9943675 "GSK3B phosphorylates CDC25A"
-xref: Reactome:R-HSA-9943676 "NEK11 phosphorylates CDC25A"
-xref: Reactome:R-HSA-9943678 "CHEK1 phosphorylates CHEK2-phosphorylated CDC25A"
-xref: Reactome:R-HSA-9943687 "PLK3 phosphorylates CDC25A"
-xref: Reactome:R-HSA-9943736 "Casein kinase I phosphorylates CDC25A"
is_a: GO:0004672 ! protein kinase activity
+property_value: skos:exactMatch EC:2.7.11.-
+property_value: skos:exactMatch MetaCyc:PROTEIN-KINASE-RXN
+property_value: skos:narrowMatch EC:2.7.11.1
+property_value: skos:narrowMatch EC:2.7.11.28
+property_value: skos:narrowMatch EC:2.7.11.29
+property_value: skos:narrowMatch EC:2.7.11.3
+property_value: skos:narrowMatch EC:2.7.11.9
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20114" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25759" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29112" xsd:anyURI
@@ -47198,6 +49476,8 @@
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0019199 ! transmembrane receptor protein kinase activity
relationship: part_of GO:0007178 ! cell surface receptor protein serine/threonine kinase signaling pathway
+property_value: skos:exactMatch EC:2.7.11.30
+property_value: skos:exactMatch RHEA:18673
[Term]
id: GO:0004676
@@ -47209,6 +49489,7 @@
synonym: "phosphatidylinositol-3-phosphate protein kinase activity" EXACT []
xref: Reactome:R-HSA-437195 "PDPK1 activates PRKCZ"
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -47218,6 +49499,7 @@
def: "DNA dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein." [GOC:mah]
comment: This reaction requires the presence of DNA.
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -47238,6 +49520,7 @@
xref: Reactome:R-HSA-6805470 "AMPK phosphorylates TP53"
is_a: GO:0004674 ! protein serine/threonine kinase activity
relationship: has_part GO:0016208 ! AMP binding
+property_value: skos:broadMatch EC:2.7.11.1
[Term]
id: GO:0004680
@@ -47325,6 +49608,8 @@
xref: Reactome:R-HSA-9619478 "CAMKK2 phosphorylates AMPK"
xref: Reactome:R-HSA-9619783 "CAMK1 phosphorylates ARHGEF7-1"
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:exactMatch EC:2.7.11.17
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004686
@@ -47346,6 +49631,10 @@
xref: MetaCyc:2.7.11.20-RXN
xref: RHEA:21436
is_a: GO:0004683 ! calcium/calmodulin-dependent protein kinase activity
+property_value: skos:exactMatch EC:2.7.11.20
+property_value: skos:exactMatch RHEA:21436
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0004687
@@ -47372,6 +49661,9 @@
xref: Reactome:R-HSA-5668978 "MYLK (MLCK) phosphorylates MRLCs of the non-muscle myosin II complex"
xref: RHEA:22004
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:exactMatch EC:2.7.11.18
+property_value: skos:exactMatch RHEA:22004
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004689
@@ -47393,6 +49685,8 @@
xref: Reactome:R-HSA-71541 "glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP"
xref: Reactome:R-HSA-71588 "glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP"
is_a: GO:0004683 ! calcium/calmodulin-dependent protein kinase activity
+property_value: skos:exactMatch EC:2.7.11.19
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004690
@@ -47424,7 +49718,7 @@
xref: EC:2.7.11.11
xref: Reactome:R-HSA-163672 "Phosphorylation of ChREBP at Thr(653) by PKA"
xref: Reactome:R-HSA-163676 "Phosphorylation of pChREBP (Thr 653) at Ser(196) by PKA"
-xref: Reactome:R-HSA-163773 "PKA tetramer:cAMP phosphorylates PF2K-Pase"
+xref: Reactome:R-HSA-163773 "Phosphorylation of PF2K-Pase by PKA catalytic subunit"
xref: Reactome:R-HSA-177275 "PKA phosphorylates DARPP-32 on Thr34"
xref: Reactome:R-HSA-177284 "PKA phosphorylates PDE4B"
xref: Reactome:R-HSA-432232 "Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA)"
@@ -47439,6 +49733,7 @@
xref: Reactome:R-HSA-9861318 "PKA phosphorylates NOS3 (eNOS) on serine-633"
is_a: GO:0004690 ! cyclic nucleotide-dependent protein kinase activity
relationship: has_part GO:0030552 ! cAMP binding
+property_value: skos:exactMatch EC:2.7.11.11
[Term]
id: GO:0004692
@@ -47462,6 +49757,8 @@
xref: Reactome:R-HSA-418549 "PKG1 phosphorylates BK channels"
is_a: GO:0004690 ! cyclic nucleotide-dependent protein kinase activity
relationship: has_part GO:0030553 ! cGMP binding
+property_value: skos:exactMatch EC:2.7.11.12
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004693
@@ -47515,7 +49812,7 @@
xref: Reactome:R-HSA-2990882 "CDK1 phosphorylates NUP98"
xref: Reactome:R-HSA-3788705 "CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2"
xref: Reactome:R-HSA-380278 "CCNB1:p-T160-CDK1 phosphorylates NUMA1"
-xref: Reactome:R-HSA-4086410 "CCNB:CDK1 phosphorylates BORA"
+xref: Reactome:R-HSA-4086410 "CDK1 phosphorylates BORA"
xref: Reactome:R-HSA-4088024 "CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1"
xref: Reactome:R-HSA-5195402 "CDK1 phosphorylates LPIN"
xref: Reactome:R-HSA-5244669 "CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments"
@@ -47526,23 +49823,16 @@
xref: Reactome:R-HSA-68944 "Orc1 is phosphorylated by cyclin A/CDK2"
xref: Reactome:R-HSA-69005 "Cdc6 protein is phosphorylated by CDK"
xref: Reactome:R-HSA-69227 "Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes"
+xref: Reactome:R-HSA-69754 "Phosphorylation of proteins involved in G2/M transition by active Cyclin A1:Cdc2 complexes"
+xref: Reactome:R-HSA-69756 "Phosphorylation of proteins involved in G2/M transition by active Cyclin A2:Cdc2 complexes"
xref: Reactome:R-HSA-9008412 "CDK4 phosphorylates RUNX2"
xref: Reactome:R-HSA-9009282 "CDK1 phosphorylates RUNX2"
xref: Reactome:R-HSA-9624800 "CDK1 phosphorylates LBR"
xref: Reactome:R-HSA-9686521 "CDK2:CCNA phosphorylates TERF2"
-xref: Reactome:R-HSA-9929482 "CDK4:CCND1 phosphorylates SPOP"
-xref: Reactome:R-HSA-9929514 "CDK1 phosphorylates CCNA"
-xref: Reactome:R-HSA-9929532 "CCNA:CDK1 phosphorylates BORA"
-xref: Reactome:R-HSA-9929535 "CCNA:CDK1 phosphorylates WEE1"
-xref: Reactome:R-HSA-9929717 "CCNA:CDK1 phosphorylates FZR1"
-xref: Reactome:R-HSA-9929719 "CCNA:CDK1 phosphorylates TICRR"
-xref: Reactome:R-HSA-9929720 "CCNA:CDK1 phosphorylates OBI1"
-xref: Reactome:R-HSA-9929721 "CCNA:CDK1 phosphorylates SGO1"
-xref: Reactome:R-HSA-9929884 "CCNA:CDK1 phosphorylates HJURP"
-xref: Reactome:R-HSA-9929904 "CCNA:CDK1 phosphorylates MIS18BP1"
-xref: Reactome:R-HSA-9929935 "CCNA:CDK1 phosphorylates CDC25B"
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0097472 ! cyclin-dependent protein kinase activity
+property_value: skos:exactMatch EC:2.7.11.22
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004694
@@ -47551,6 +49841,7 @@
def: "Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate." [GOC:mah, InterPro:IPR015516]
is_a: GO:0004674 ! protein serine/threonine kinase activity
relationship: part_of GO:0010998 ! regulation of translational initiation by eIF2 alpha phosphorylation
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -47582,11 +49873,37 @@
synonym: "protein kinase Cepsilon activity" NARROW [EC:2.7.11.13]
synonym: "STK24" RELATED [EC:2.7.11.13]
xref: EC:2.7.11.13
+xref: Reactome:R-HSA-1433508 "PKC alpha interacts with and phosphorylates KIT"
+xref: Reactome:R-HSA-193703 "IKKbeta is activated"
+xref: Reactome:R-HSA-198314 "DAG stimulates protein kinase C-delta"
+xref: Reactome:R-HSA-2179413 "Activated PKC-alpha activate MMP3"
+xref: Reactome:R-HSA-2730863 "Phosphorylation of CARMA1 by PKC-theta"
+xref: Reactome:R-HSA-374664 "Phosphorylation and activation of Ezrin"
+xref: Reactome:R-HSA-429698 "PRKD1,2,3 phosphorylates CERT1-2"
+xref: Reactome:R-HSA-450533 "PKCdelta phosphorylates HuR"
+xref: Reactome:R-HSA-450550 "PKCalpha phosphorylates HuR"
+xref: Reactome:R-HSA-5138432 "DVL2 is phosphorylated by PKC"
xref: Reactome:R-HSA-5218805 "PKC autophosphorylates"
+xref: Reactome:R-HSA-5218823 "PKC phosphorylates sphingosine kinase 1"
+xref: Reactome:R-HSA-5229194 "Depolymerization of lamin filaments after PKC-mediated phosphorylation"
+xref: Reactome:R-HSA-5623667 "PDPK1 phosphorylates PKN1,2,3"
+xref: Reactome:R-HSA-5625784 "PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters"
+xref: Reactome:R-HSA-5671749 "p-T774-PKN1 phosphorylates CDC25C"
+xref: Reactome:R-HSA-74615 "PRKCA/Q phosphorylate RGS9-1:GN5B:RGS9BP"
xref: Reactome:R-HSA-751040 "PKC phosphorylates G alpha (z)"
+xref: Reactome:R-HSA-8932284 "PKC phosphorylates NFE2L2"
+xref: Reactome:R-HSA-8934446 "Activated PKC phosphorylates SHC1"
+xref: Reactome:R-HSA-9010681 "PKC phosphorylates ROBO3.1"
+xref: Reactome:R-HSA-9021357 "PRKCI phosphorylates ELF3"
+xref: Reactome:R-HSA-909552 "Phosphorylation of STAT1 at Ser727"
+xref: Reactome:R-HSA-927889 "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)"
xref: Reactome:R-HSA-9626817 "PKC phosphorylates NCF1"
+xref: Reactome:R-HSA-9632858 "PRKCZ autophosphorylates downstream of estrogen stimulation"
+xref: Reactome:R-HSA-9796053 "PRKCI phosphorylates NFE2L2"
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:exactMatch EC:2.7.11.13
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25457" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004698
@@ -47597,21 +49914,13 @@
synonym: "conventional protein kinase C activity" EXACT [PMID:9601053]
xref: Reactome:R-HSA-114683 "Phosphorylation of Platelet Sec-1"
xref: Reactome:R-HSA-114684 "Phosphorylation of Syntaxin-4"
-xref: Reactome:R-HSA-1433508 "PKC alpha interacts with and phosphorylates KIT"
-xref: Reactome:R-HSA-2179413 "Activated PKC-alpha activate MMP3"
xref: Reactome:R-HSA-416639 "Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites"
xref: Reactome:R-HSA-421007 "Endocytosis of Ca impermeable AMPA receptors"
-xref: Reactome:R-HSA-450550 "PKCalpha phosphorylates HuR"
-xref: Reactome:R-HSA-5138432 "DVL2 is phosphorylated by PKC"
-xref: Reactome:R-HSA-5218823 "PKC phosphorylates sphingosine kinase 1"
-xref: Reactome:R-HSA-5229194 "Depolymerization of lamin filaments after PKC-mediated phosphorylation"
-xref: Reactome:R-HSA-74615 "PRKCA/Q phosphorylate RGS9-1:GN5B:RGS9BP"
-xref: Reactome:R-HSA-8934446 "Activated PKC phosphorylates SHC1"
xref: Reactome:R-HSA-8986937 "MECP2 is phosphorylated at T308"
xref: Reactome:R-HSA-9005561 "Active PKA, CaMK IV do not phosphorylate MECP2 mutants R306C,(R306H) at T308"
-xref: Reactome:R-HSA-9010681 "PKC phosphorylates ROBO3.1"
is_a: GO:0004697 ! diacylglycerol-dependent serine/threonine kinase activity
is_a: GO:0009931 ! calcium-dependent protein serine/threonine kinase activity
+property_value: skos:broadMatch EC:2.7.11.13
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25457" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -47623,15 +49932,9 @@
synonym: "atypical protein kinase C activity" RELATED []
synonym: "calcium-independent PKC activity" EXACT []
synonym: "novel protein kinase C activity" EXACT [PMID:9601053]
-xref: Reactome:R-HSA-198314 "DAG stimulates protein kinase C-delta"
-xref: Reactome:R-HSA-2730863 "Phosphorylation of CARMA1 by PKC-theta"
-xref: Reactome:R-HSA-374664 "Phosphorylation and activation of Ezrin"
-xref: Reactome:R-HSA-429698 "PRKD1,2,3 phosphorylates CERT1-2"
-xref: Reactome:R-HSA-450533 "PKCdelta phosphorylates HuR"
xref: Reactome:R-HSA-5607740 "PKC-delta phosphorylates CARD9"
-xref: Reactome:R-HSA-8932284 "PKC phosphorylates NFE2L2"
-xref: Reactome:R-HSA-909552 "Phosphorylation of STAT1 at Ser727"
is_a: GO:0004697 ! diacylglycerol-dependent serine/threonine kinase activity
+property_value: skos:broadMatch EC:2.7.11.13
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25457" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -47666,6 +49969,9 @@
xref: EC:2.7.11.16
xref: RHEA:12008
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:exactMatch EC:2.7.11.16
+property_value: skos:exactMatch RHEA:12008
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004704
@@ -47693,6 +49999,7 @@
xref: Reactome:R-HSA-9673789 "Activated JNK phosphorylates c-JUN"
is_a: GO:0004707 ! MAP kinase activity
relationship: part_of GO:0007254 ! JNK cascade
+property_value: skos:broadMatch EC:2.7.11.24
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -47703,6 +50010,7 @@
synonym: "JNK kinase kinase activity" RELATED []
synonym: "JNKKK" EXACT []
is_a: GO:0004709 ! MAP kinase kinase kinase activity
+property_value: skos:broadMatch EC:2.7.11.25
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -47746,6 +50054,8 @@
xref: Reactome:R-HSA-9825759 "MAPK-dependent phosphorylation of KARS"
is_a: GO:0004674 ! protein serine/threonine kinase activity
relationship: part_of GO:0000165 ! MAPK cascade
+property_value: skos:exactMatch EC:2.7.11.24
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004708
@@ -47781,7 +50091,9 @@
xref: Reactome:R-HSA-5218804 "p38 MAPK activation by VEGFR"
is_a: GO:0004712 ! protein serine/threonine/tyrosine kinase activity
relationship: part_of GO:0000165 ! MAPK cascade
+property_value: skos:exactMatch EC:2.7.12.2
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27856" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004709
@@ -47818,6 +50130,8 @@
xref: Reactome:R-HSA-933530 "Activation of IKK by MEKK1"
is_a: GO:0004674 ! protein serine/threonine kinase activity
relationship: part_of GO:0000165 ! MAPK cascade
+property_value: skos:exactMatch EC:2.7.11.25
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004711
@@ -47825,6 +50139,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP." [GOC:mah, PMID:9822608]
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -47848,6 +50163,7 @@
xref: Reactome:R-HSA-6802941 "RAF is paradoxically phosphorylated downstream of kinase-inactive RAF"
xref: Reactome:R-HSA-9656212 "Phosphorylation of RAF1 mutants"
is_a: GO:0004672 ! protein kinase activity
+property_value: skos:exactMatch EC:2.7.12.1
[Term]
id: GO:0004713
@@ -47884,7 +50200,7 @@
xref: Reactome:R-HSA-1524186 "Phosphorylation of PLCgamma by PDGFR"
xref: Reactome:R-HSA-1671691 "PRLR-bound STAT5 is phosphorylated"
xref: Reactome:R-HSA-170070 "Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes"
-xref: Reactome:R-HSA-170156 "WEE1 phosphorylates CCNA:CDK1"
+xref: Reactome:R-HSA-170156 "Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes"
xref: Reactome:R-HSA-170991 "SRC-1 autophosphorylates"
xref: Reactome:R-HSA-171011 "Binding and activation of MAP Kinase"
xref: Reactome:R-HSA-174164 "Phosphorylation of Cyclin A:Cdk2 at Tyr 15"
@@ -48243,10 +50559,10 @@
xref: Reactome:R-HSA-9860759 "p-T816-PKN2 phosphorylates AKT1 on serine-308"
xref: Reactome:R-HSA-9861469 "p-Y397-PTK2 (FAK) phosphorylates CHUK (IKKA)"
xref: Reactome:R-HSA-9865196 "p-Y393-ABL1 phosphorylates tyrosine-407 of YAP1"
-xref: Reactome:R-HSA-9931290 "IL6-activated JAK1 phosphorylates CD274"
-xref: Reactome:R-HSA-9934751 "CDH1 is phosphorylated on tyrosine residues"
xref: RHEA:10596
is_a: GO:0004672 ! protein kinase activity
+property_value: skos:exactMatch EC:2.7.10.-
+property_value: skos:exactMatch RHEA:10596
[Term]
id: GO:0004714
@@ -48301,6 +50617,7 @@
xref: Reactome:R-HSA-8987255 "IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3"
is_a: GO:0004713 ! protein tyrosine kinase activity
is_a: GO:0019199 ! transmembrane receptor protein kinase activity
+property_value: skos:exactMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
[Term]
@@ -48335,6 +50652,7 @@
xref: Reactome:R-HSA-879910 "JAK2 is phosphorylated, activated"
xref: Reactome:R-HSA-8871373 "BMX phosphorylates RUFY1"
is_a: GO:0004713 ! protein tyrosine kinase activity
+property_value: skos:exactMatch EC:2.7.10.2
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
[Term]
@@ -48384,6 +50702,9 @@
xref: RHEA:12705
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
is_a: GO:0051998 ! protein carboxyl O-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.77
+property_value: skos:exactMatch RHEA:12705
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004720
@@ -48401,6 +50722,9 @@
xref: RHEA:24544
is_a: GO:0052597 ! diamine oxidase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:1.4.3.13
+property_value: skos:exactMatch RHEA:24544
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004721
@@ -48413,13 +50737,14 @@
synonym: "protein phosphatase-2A activity" NARROW []
synonym: "protein phosphatase-2B activity" NARROW []
synonym: "protein phosphatase-2C activity" NARROW []
+xref: EC:3.1.3.55
xref: Reactome:R-HSA-112383 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein"
xref: Reactome:R-HSA-113503 "PP2A mediated localization of RB1 protein in chromatin"
xref: Reactome:R-HSA-1363274 "Dephosphorylation of p107 (RBL1) by PP2A"
xref: Reactome:R-HSA-1363276 "Dephosphorylation of p130 (RBL2) by PP2A"
xref: Reactome:R-HSA-167072 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein"
xref: Reactome:R-HSA-170153 "Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases"
-xref: Reactome:R-HSA-170158 "CDC25A dephosphorylates CCNA:CDK1"
+xref: Reactome:R-HSA-170158 "Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes"
xref: Reactome:R-HSA-170161 "Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B"
xref: Reactome:R-HSA-174110 "Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2"
xref: Reactome:R-HSA-174124 "Dephosphorylation of phospho-Cdh1"
@@ -48429,6 +50754,7 @@
xref: Reactome:R-HSA-9636684 "NdkA dephosphorylates RAB5A:GTP,RAB7A:GTP"
is_a: GO:0016791 ! phosphatase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:narrowMatch EC:3.1.3.55
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25787" xsd:anyURI
[Term]
@@ -48467,8 +50793,8 @@
xref: MetaCyc:3.1.3.16-RXN
xref: Reactome:R-HSA-1295632 "PPA2A dephosphorylates SPRY2"
xref: Reactome:R-HSA-163568 "phosphorylated perilipin + H2O -> perilipin + orthophosphate"
-xref: Reactome:R-HSA-163689 "PP2A complex dephosphorylates pChREBP (MLXIPL)"
-xref: Reactome:R-HSA-163750 "PP2A complex dephosphorylates pPFKFB1"
+xref: Reactome:R-HSA-163689 "Dephosphorylation of pChREBP (Ser 196) by PP2A"
+xref: Reactome:R-HSA-163750 "Dephosphorylation of phosphoPFKFB1 by PP2A complex"
xref: Reactome:R-HSA-1638821 "PP2A-B56 dephosphorylates centromeric cohesin"
xref: Reactome:R-HSA-199425 "PHLPP dephosphorylates S473 in AKT"
xref: Reactome:R-HSA-199959 "ERKs are inactivated by protein phosphatase 2A"
@@ -48491,6 +50817,7 @@
xref: Reactome:R-HSA-5683405 "PPP5C dephosphorylates TP53BP1"
xref: Reactome:R-HSA-5687758 "PPP4C:PPP4R2 dephosphorylates RPA2"
xref: Reactome:R-HSA-5692754 "CDC14A,B dephosphorylate p-3S,T MAPK6"
+xref: Reactome:R-HSA-5693153 "PPM1K dephosphorylates p-BCKDH"
xref: Reactome:R-HSA-5694421 "PP6 dephosphorylates SEC24"
xref: Reactome:R-HSA-6792863 "PP2A-PP2R5C dephosphorylates MDM2"
xref: Reactome:R-HSA-6811504 "AKT1 dephosphorylation by PP2A-B56-beta,gamma"
@@ -48509,9 +50836,15 @@
xref: Reactome:R-HSA-9865226 "PP2A dephosphorylates serine-127 of YAP1"
xref: Reactome:R-HSA-9865238 "PP2A dephosphorylates serine-715 of PDE4D5 in p-S715-PDE4D5:integrin alpha5:integrin beta1:fibronectin"
xref: Reactome:R-HSA-9912527 "H139Hfs13* PPM1K does not dephosphorylate BCKDH"
+xref: RHEA:20629
+xref: RHEA:47004
is_a: GO:0004721 ! phosphoprotein phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.16
+property_value: skos:narrowMatch RHEA:20629
+property_value: skos:narrowMatch RHEA:47004
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22458" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25787" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004723
@@ -48587,6 +50920,9 @@
xref: Reactome:R-HSA-997326 "Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP"
xref: RHEA:10684
is_a: GO:0004721 ! phosphoprotein phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.48
+property_value: skos:exactMatch RHEA:10684
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004726
@@ -48599,6 +50935,7 @@
xref: Reactome:R-HSA-177935 "SHP2 dephosphorylates Tyr 992 on EGFR"
xref: Reactome:R-HSA-9635739 "PTPN7 dephosphorylates p-T,Y-MAPKs"
is_a: GO:0004725 ! protein tyrosine phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.48
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -48636,6 +50973,10 @@
xref: RHEA:25576
is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
is_a: GO:0070818 ! protoporphyrinogen oxidase activity
+property_value: skos:exactMatch EC:1.3.3.4
+property_value: skos:exactMatch KEGG_REACTION:R03222
+property_value: skos:exactMatch MetaCyc:PROTOPORGENOXI-RXN
+property_value: skos:exactMatch RHEA:25576
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -48660,6 +51001,9 @@
xref: RHEA:18337
is_a: GO:0016836 ! hydro-lyase activity
relationship: part_of GO:0001522 ! pseudouridine synthesis
+property_value: skos:exactMatch EC:4.2.1.70
+property_value: skos:exactMatch RHEA:18337
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004731
@@ -48687,6 +51031,9 @@
xref: Reactome:R-HSA-9755044 "PNP trimer transforms RBV to T-CONH2"
xref: RHEA:19805
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.1
+property_value: skos:exactMatch RHEA:19805
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004732
@@ -48698,7 +51045,10 @@
xref: MetaCyc:PYRIDOXAL-OXIDASE-RXN
xref: RHEA:23724
is_a: GO:0004031 ! aldehyde oxidase activity
+property_value: skos:exactMatch EC:1.2.3.8
+property_value: skos:exactMatch RHEA:23724
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24731" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004733
@@ -48720,7 +51070,10 @@
xref: RHEA:15817
is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
relationship: part_of GO:0042823 ! pyridoxal phosphate biosynthetic process
+property_value: skos:exactMatch EC:1.4.3.5
+property_value: skos:exactMatch RHEA:15817
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22748" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004734
@@ -48733,6 +51086,9 @@
xref: MetaCyc:1.5.4.1-RXN
xref: RHEA:10720
is_a: GO:0016648 ! oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor
+property_value: skos:exactMatch EC:1.5.4.1
+property_value: skos:exactMatch RHEA:10720
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004735
@@ -48748,10 +51104,13 @@
xref: EC:1.5.1.2
xref: MetaCyc:PYRROLINECARBREDUCT-RXN
xref: Reactome:R-HSA-6783939 "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro"
-xref: Reactome:R-HSA-6783955 "PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro"
+xref: Reactome:R-HSA-6783955 "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro"
xref: Reactome:R-HSA-70664 "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro"
xref: RHEA:14109
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.2
+property_value: skos:exactMatch RHEA:14109
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004736
@@ -48766,6 +51125,9 @@
xref: Reactome:R-HSA-70501 "PC carboxylates PYR to OA"
xref: RHEA:20844
is_a: GO:0016885 ! ligase activity, forming carbon-carbon bonds
+property_value: skos:exactMatch EC:6.4.1.1
+property_value: skos:exactMatch RHEA:20844
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004737
@@ -48781,6 +51143,9 @@
xref: MetaCyc:PYRUVATE-DECARBOXYLASE-RXN
xref: RHEA:11628
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.1
+property_value: skos:exactMatch RHEA:11628
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004738
@@ -48807,6 +51172,10 @@
xref: Reactome:R-HSA-9861734 "PDH E1 decarboxylates PYR, transferring acetyl to DLAT"
xref: RHEA:19189
is_a: GO:0016624 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
+property_value: skos:broadMatch EC:1.2.1.104
+property_value: skos:broadMatch RHEA:28042
+property_value: skos:exactMatch EC:1.2.4.1
+property_value: skos:exactMatch RHEA:19189
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24350" xsd:anyURI
[Term]
@@ -48824,6 +51193,9 @@
xref: Reactome:R-HSA-203946 "PDK isozymes phosphorylate PDHC subunit E1"
xref: RHEA:23052
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:exactMatch EC:2.7.11.2
+property_value: skos:exactMatch MetaCyc:2.7.11.2-RXN
+property_value: skos:exactMatch RHEA:23052
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29095" xsd:anyURI
[Term]
@@ -48840,7 +51212,10 @@
xref: Reactome:R-HSA-204169 "PDP1,2 dephosphorylate p-lipo-PDH"
xref: RHEA:12669
is_a: GO:0004722 ! protein serine/threonine phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.43
+property_value: skos:exactMatch RHEA:12669
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26194" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004742
@@ -48871,6 +51246,10 @@
xref: RHEA:17017
is_a: GO:0016418 ! S-acetyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:broadMatch EC:1.2.1.104
+property_value: skos:broadMatch RHEA:28042
+property_value: skos:exactMatch EC:2.3.1.12
+property_value: skos:exactMatch RHEA:17017
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17835" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24350" xsd:anyURI
@@ -48888,6 +51267,9 @@
xref: RHEA:18157
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
relationship: part_of GO:0006096 ! glycolytic process
+property_value: skos:exactMatch EC:2.7.1.40
+property_value: skos:exactMatch MetaCyc:PEPDEPHOS-RXN
+property_value: skos:exactMatch RHEA:18157
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
@@ -48921,11 +51303,16 @@
xref: Reactome:R-HSA-5362518 "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL"
xref: Reactome:R-HSA-5362564 "ADH1A,1C,4 oxidise atROL to atRAL in vitro"
xref: Reactome:R-HSA-5362721 "RDH5,RDH11 oxidise 11cROL to 11cRAL"
+xref: RHEA:21284
xref: RHEA:48488
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.105
+property_value: skos:exactMatch RHEA:48488
+property_value: skos:narrowMatch RHEA:21284
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20980" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004746
@@ -48944,6 +51331,9 @@
xref: MetaCyc:RIBOFLAVIN-SYN-RXN
xref: RHEA:20772
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.9
+property_value: skos:exactMatch RHEA:20772
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004747
@@ -48960,6 +51350,9 @@
xref: RHEA:13697
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.15
+property_value: skos:exactMatch RHEA:13697
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004748
@@ -48978,6 +51371,9 @@
xref: Reactome:R-HSA-111804 "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)"
xref: RHEA:23252
is_a: GO:0061731 ! ribonucleoside-diphosphate reductase activity
+property_value: skos:exactMatch EC:1.17.4.1
+property_value: skos:exactMatch RHEA:23252
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004749
@@ -49005,10 +51401,15 @@
xref: EC:2.7.6.1
xref: KEGG_REACTION:R01049
xref: MetaCyc:PRPPSYN-RXN
-xref: Reactome:R-HSA-111215 "PRPS1 dimer pyrophosphorylates R5P using dATP"
-xref: Reactome:R-HSA-73580 "PRPS dimers pyrophosphorylate R5P using ATP"
+xref: Reactome:R-HSA-111215 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate"
+xref: Reactome:R-HSA-73580 "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate"
xref: RHEA:15609
is_a: GO:0016778 ! diphosphotransferase activity
+property_value: skos:exactMatch EC:2.7.6.1
+property_value: skos:exactMatch KEGG_REACTION:R01049
+property_value: skos:exactMatch MetaCyc:PRPPSYN-RXN
+property_value: skos:exactMatch RHEA:15609
+property_value: skos:relatedMatch MetaCyc:PWY0-662
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -49035,10 +51436,13 @@
xref: EC:5.1.3.1
xref: KEGG_REACTION:R01529
xref: MetaCyc:RIBULP3EPIM-RXN
-xref: Reactome:R-HSA-199803 "RPE dimers isomerize XY5P to RU5P"
+xref: Reactome:R-HSA-199803 "xylulose 5-phosphate <=> D-ribulose 5-phosphate"
xref: Reactome:R-HSA-71303 "RPE dimers isomerise RU5P to XY5P"
xref: RHEA:13677
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.1
+property_value: skos:exactMatch RHEA:13677
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004751
@@ -49058,12 +51462,15 @@
xref: EC:5.3.1.6
xref: KEGG_REACTION:R01056
xref: MetaCyc:RIB5PISOM-RXN
-xref: Reactome:R-HSA-177784 "RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate"
+xref: Reactome:R-HSA-177784 "ribose 5-phosphate <=> D-ribulose 5-phosphate"
xref: Reactome:R-HSA-5660013 "Defective RPIA does not isomerize RU5P to R5P"
xref: Reactome:R-HSA-5660015 "Defective RPIA does not isomerize R5P to RU5P"
-xref: Reactome:R-HSA-71306 "RPIA isomerizes D-ribulose 5-phosphate to ribose 5-phosphate"
+xref: Reactome:R-HSA-71306 "D-ribulose 5-phosphate <=> ribose 5-phosphate"
xref: RHEA:14657
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.6
+property_value: skos:exactMatch RHEA:14657
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004753
@@ -49089,6 +51496,9 @@
xref: MetaCyc:1.5.1.7-RXN
xref: RHEA:12440
is_a: GO:0004753 ! saccharopine dehydrogenase activity
+property_value: skos:exactMatch EC:1.5.1.7
+property_value: skos:exactMatch RHEA:12440
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004755
@@ -49108,6 +51518,9 @@
xref: MetaCyc:RXN3O-127
xref: RHEA:10020
is_a: GO:0004753 ! saccharopine dehydrogenase activity
+property_value: skos:exactMatch EC:1.5.1.10
+property_value: skos:exactMatch RHEA:10020
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004756
@@ -49127,6 +51540,9 @@
xref: UM-BBD_reactionID:r0833
is_a: GO:0016301 ! kinase activity
is_a: GO:0016781 ! phosphotransferase activity, paired acceptors
+property_value: skos:exactMatch EC:2.7.9.3
+property_value: skos:exactMatch RHEA:18737
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004757
@@ -49138,7 +51554,12 @@
xref: MetaCyc:SEPIAPTERIN-REDUCTASE-RXN
xref: Reactome:R-HSA-1475414 "PTHP is reduced to BH4 by sepiapterin reductase (SPR)"
xref: Reactome:R-HSA-1497869 "Salvage - Sepiapterin is reduced to q-BH2"
+xref: RHEA:18953
+xref: RHEA:32627
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.153
+property_value: skos:narrowMatch RHEA:18953
+property_value: skos:narrowMatch RHEA:32627
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
[Term]
@@ -49155,6 +51576,9 @@
xref: Reactome:R-HSA-428127 "SPTLC complexes transfer acyl-CoA onto serine"
xref: RHEA:14761
is_a: GO:0016454 ! C-palmitoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.50
+property_value: skos:exactMatch RHEA:14761
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004760
@@ -49177,6 +51601,9 @@
xref: MetaCyc:SERINE--PYRUVATE-AMINOTRANSFERASE-RXN
xref: RHEA:22852
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.51
+property_value: skos:exactMatch RHEA:22852
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004764
@@ -49195,7 +51622,11 @@
xref: MetaCyc:SHIKIMATE-5-DEHYDROGENASE-RXN
xref: RHEA:17737
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.1.1.282
+property_value: skos:exactMatch EC:1.1.1.25
+property_value: skos:exactMatch RHEA:17737
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004765
@@ -49211,6 +51642,9 @@
xref: RHEA:13121
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.71
+property_value: skos:exactMatch RHEA:13121
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004766
@@ -49227,6 +51661,9 @@
xref: Reactome:R-HSA-351215 "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine"
xref: RHEA:12721
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.16
+property_value: skos:exactMatch RHEA:12721
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004767
@@ -49247,8 +51684,12 @@
xref: Reactome:R-HSA-1640164 "ENPP7 hydrolyzes sphingomyelin"
xref: Reactome:R-HSA-193706 "Production of ceramide which can activate JNK and other targets"
xref: RHEA:19253
-is_a: GO:0004620 ! phospholipase activity
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+is_a: GO:0120570 ! sphingophospholipase activity
+property_value: skos:exactMatch EC:3.1.4.12
+property_value: skos:exactMatch RHEA:19253
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31030" xsd:anyURI
[Term]
id: GO:0004768
@@ -49268,7 +51709,10 @@
xref: Reactome:R-HSA-8847579 "SCD5 desaturates ST-CoA to OLE-CoA"
xref: RHEA:19721
is_a: GO:0016215 ! acyl-CoA desaturase activity
+property_value: skos:exactMatch EC:1.14.19.1
+property_value: skos:exactMatch RHEA:19721
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24103" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004769
@@ -49299,6 +51743,9 @@
xref: Reactome:R-HSA-6807052 "EBP isomerizes ZYMSTNL to LTHSOL"
xref: RHEA:14709
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.1
+property_value: skos:exactMatch RHEA:14709
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004771
@@ -49326,6 +51773,9 @@
xref: RHEA:10100
is_a: GO:0016298 ! lipase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.13
+property_value: skos:exactMatch MetaCyc:STEROL-ESTERASE-RXN
+property_value: skos:exactMatch RHEA:10100
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28339" xsd:anyURI
[Term]
@@ -49340,6 +51790,9 @@
xref: MetaCyc:RXN-20233
xref: RHEA:59816
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.26
+property_value: skos:exactMatch MetaCyc:RXN-20233
+property_value: skos:exactMatch RHEA:59816
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -49364,6 +51817,9 @@
xref: Reactome:R-HSA-1606839 "ARSC hydrolyzes steroid sulfates"
xref: RHEA:19873
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.2
+property_value: skos:exactMatch RHEA:19873
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004774
@@ -49389,6 +51845,9 @@
xref: Reactome:R-HSA-70997 "SUCLG1/A2 cleaves succinyl-CoA"
xref: RHEA:17661
is_a: GO:0004774 ! succinate-CoA ligase activity
+property_value: skos:exactMatch EC:6.2.1.5
+property_value: skos:exactMatch RHEA:17661
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004776
@@ -49407,6 +51866,9 @@
xref: Reactome:R-HSA-71775 "SUCLG1/G2 cleaves succinyl-CoA"
xref: RHEA:22120
is_a: GO:0004774 ! succinate-CoA ligase activity
+property_value: skos:exactMatch EC:6.2.1.4
+property_value: skos:exactMatch RHEA:22120
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004777
@@ -49425,6 +51887,9 @@
xref: Reactome:R-HSA-888548 "ALDH5A1 dehydrogenates SUCCSA to SUCCA"
xref: RHEA:13217
is_a: GO:0009013 ! succinate-semialdehyde dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.2.1.24
+property_value: skos:exactMatch RHEA:13217
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004778
@@ -49439,6 +51904,9 @@
xref: MetaCyc:SUCCINYL-COA-HYDROLASE-RXN
xref: RHEA:11516
is_a: GO:0016289 ! acyl-CoA hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.3
+property_value: skos:exactMatch RHEA:11516
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004779
@@ -49463,6 +51931,9 @@
xref: MetaCyc:SULFATE-ADENYLYLTRANSFERASE-ADP-RXN
xref: RHEA:16529
is_a: GO:0004779 ! sulfate adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.5
+property_value: skos:exactMatch RHEA:16529
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004781
@@ -49484,7 +51955,10 @@
xref: Reactome:R-HSA-3560794 "Defective PAPSS2 does not transfer SO4(2-) group to ATP to form APS"
xref: RHEA:18133
is_a: GO:0004779 ! sulfate adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.4
+property_value: skos:exactMatch RHEA:18133
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28907" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004782
@@ -49508,6 +51982,9 @@
xref: Reactome:R-HSA-1655443 "PXKLP-K305-CSAD decarboxylates 3-sulfinoalanine to hypotaurine"
xref: RHEA:16877
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.29
+property_value: skos:exactMatch RHEA:16877
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004783
@@ -49526,6 +52003,9 @@
xref: RHEA:13801
is_a: GO:0016002 ! sulfite reductase activity
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:exactMatch EC:1.8.1.2
+property_value: skos:exactMatch RHEA:13801
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004784
@@ -49577,6 +52057,9 @@
is_a: GO:0016209 ! antioxidant activity
is_a: GO:0016721 ! oxidoreductase activity, acting on superoxide radicals as acceptor
relationship: part_of GO:0019430 ! removal of superoxide radicals
+property_value: skos:exactMatch EC:1.15.1.1
+property_value: skos:exactMatch RHEA:20696
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004786
@@ -49602,7 +52085,9 @@
synonym: "TPPase activity" EXACT []
xref: RHEA:27998
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch RHEA:27998
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004788
@@ -49623,6 +52108,9 @@
xref: Reactome:R-HSA-196761 "2xTPK1:Mg2+ phosphorylates THMN"
xref: RHEA:11576
is_a: GO:0016778 ! diphosphotransferase activity
+property_value: skos:exactMatch EC:2.7.6.2
+property_value: skos:exactMatch RHEA:11576
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004789
@@ -49644,6 +52132,9 @@
xref: MetaCyc:THI-P-SYN-RXN
xref: RHEA:22328
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.3
+property_value: skos:exactMatch RHEA:22328
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004790
@@ -49659,6 +52150,9 @@
xref: RHEA:19613
is_a: GO:0008172 ! S-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.96
+property_value: skos:exactMatch RHEA:19613
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004791
@@ -49681,9 +52175,12 @@
xref: RHEA:20345
is_a: GO:0016209 ! antioxidant activity
is_a: GO:0047134 ! protein-disulfide reductase [NAD(P)H] activity
+property_value: skos:exactMatch EC:1.8.1.9
+property_value: skos:exactMatch RHEA:20345
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22101" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25459" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004792
@@ -49703,6 +52200,9 @@
xref: Reactome:R-HSA-9013198 "TST transfers sulfur from S2O3(2-) to HCN to form HSCN"
xref: RHEA:16881
is_a: GO:0016783 ! sulfurtransferase activity
+property_value: skos:exactMatch EC:2.8.1.1
+property_value: skos:exactMatch RHEA:16881
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004793
@@ -49716,6 +52216,11 @@
xref: MetaCyc:THREONINE-ALDOLASE-RXN
xref: RHEA:19625
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:broadMatch EC:2.1.2.1
+property_value: skos:broadMatch EC:4.1.2.48
+property_value: skos:exactMatch EC:4.1.2.5
+property_value: skos:exactMatch MetaCyc:THREONINE-ALDOLASE-RXN
+property_value: skos:exactMatch RHEA:19625
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30653" xsd:anyURI
[Term]
@@ -49735,10 +52240,12 @@
synonym: "threonine dehydratase activity" BROAD []
xref: EC:4.3.1.19
xref: MetaCyc:THREDEHYD-RXN
-xref: Reactome:R-HSA-9014627 "SDS dimers:PXLP convert L-Thr to 2OBUTA"
xref: RHEA:22108
xref: UM-BBD_reactionID:r0433
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.19
+property_value: skos:exactMatch RHEA:22108
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004795
@@ -49752,6 +52259,9 @@
xref: MetaCyc:THRESYN-RXN
xref: RHEA:10840
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.1
+property_value: skos:exactMatch RHEA:10840
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004796
@@ -49771,6 +52281,9 @@
xref: Reactome:R-HSA-76500 "TBXAS1 isomerises PGH2 to TXA2"
xref: RHEA:17137
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:exactMatch EC:5.3.99.5
+property_value: skos:exactMatch RHEA:17137
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004797
@@ -49785,6 +52298,9 @@
xref: MetaCyc:THYKI-RXN
xref: RHEA:19129
is_a: GO:0019136 ! deoxynucleoside kinase activity
+property_value: skos:exactMatch EC:2.7.1.21
+property_value: skos:exactMatch RHEA:19129
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004798
@@ -49804,6 +52320,10 @@
xref: MetaCyc:DTMPKI-RXN
xref: RHEA:13517
is_a: GO:0047507 ! deoxynucleoside phosphate kinase activity, ATP as phosphate donor
+property_value: skos:broadMatch EC:2.7.4.12
+property_value: skos:exactMatch EC:2.7.4.9
+property_value: skos:exactMatch MetaCyc:DTMPKI-RXN
+property_value: skos:exactMatch RHEA:13517
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29533" xsd:anyURI
[Term]
@@ -49822,6 +52342,9 @@
xref: Reactome:R-HSA-73605 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate"
xref: RHEA:12104
is_a: GO:0042083 ! 5,10-methylenetetrahydrofolate-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.45
+property_value: skos:exactMatch RHEA:12104
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004800
@@ -49844,7 +52367,10 @@
xref: Reactome:R-HSA-350869 "Thyroxine is deiodinated to reverse triiodothyronine (RT3)"
xref: RHEA:19745
is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond
+property_value: skos:exactMatch EC:1.21.99.4
+property_value: skos:exactMatch RHEA:19745
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004801
@@ -49863,7 +52389,10 @@
xref: Reactome:R-HSA-71334 "sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate"
xref: RHEA:17053
is_a: GO:0016744 ! transketolase or transaldolase activity
+property_value: skos:exactMatch EC:2.2.1.2
+property_value: skos:exactMatch RHEA:17053
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004802
@@ -49875,11 +52404,20 @@
synonym: "glycolaldehydetransferase activity" RELATED [EC:2.2.1.1]
synonym: "sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity" NARROW [EC:2.2.1.1]
xref: EC:2.2.1.1
+xref: MetaCyc:1TRANSKETO-RXN
+xref: MetaCyc:2TRANSKETO-RXN
xref: Reactome:R-HSA-163741 "D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate"
xref: Reactome:R-HSA-163751 "D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate"
xref: Reactome:R-HSA-71324 "ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate"
xref: Reactome:R-HSA-71335 "xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate"
+xref: RHEA:10508
+xref: RHEA:27626
is_a: GO:0016744 ! transketolase or transaldolase activity
+property_value: skos:exactMatch EC:2.2.1.1
+property_value: skos:narrowMatch MetaCyc:1TRANSKETO-RXN
+property_value: skos:narrowMatch MetaCyc:2TRANSKETO-RXN
+property_value: skos:narrowMatch RHEA:10508
+property_value: skos:narrowMatch RHEA:27626
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29091" xsd:anyURI
[Term]
@@ -49906,7 +52444,10 @@
xref: MetaCyc:TREHALOSEPHOSPHA-RXN
xref: RHEA:23420
is_a: GO:0050308 ! sugar-phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.12
+property_value: skos:exactMatch RHEA:23420
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26845" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004806
@@ -49964,6 +52505,10 @@
xref: RHEA:12044
is_a: GO:0016298 ! lipase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:broadMatch EC:3.1.1.79
+property_value: skos:exactMatch EC:3.1.1.3
+property_value: skos:exactMatch MetaCyc:RXN-19278
+property_value: skos:exactMatch RHEA:12044
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28339" xsd:anyURI
@@ -49982,10 +52527,13 @@
xref: EC:5.3.1.1
xref: KEGG_REACTION:R01015
xref: MetaCyc:TRIOSEPISOMERIZATION-RXN
-xref: Reactome:R-HSA-70454 "TPI1 dimer isomerizes DHAP to GA3P"
-xref: Reactome:R-HSA-70481 "TPI1 dimer isomerizes GA3P to DHAP"
+xref: Reactome:R-HSA-70454 "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate"
+xref: Reactome:R-HSA-70481 "TPI1 isomerizes GA3P to DHAP"
xref: RHEA:18585
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.1
+property_value: skos:exactMatch RHEA:18585
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004808
@@ -50001,7 +52549,10 @@
xref: RHEA:19569
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
is_a: GO:0016300 ! tRNA (uridine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.61
+property_value: skos:exactMatch RHEA:19569
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26144" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004809
@@ -50053,7 +52604,10 @@
xref: RHEA:14433
is_a: GO:0070567 ! cytidylyltransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.7.7.72
+property_value: skos:exactMatch RHEA:14433
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19854" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004812
@@ -50069,6 +52623,8 @@
xref: EC:6.1.1.-
is_a: GO:0016875 ! ligase activity, forming carbon-oxygen bonds
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:6.1.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004813
@@ -50093,6 +52649,9 @@
xref: Reactome:R-HSA-380177 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate"
xref: RHEA:12540
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.7
+property_value: skos:exactMatch RHEA:12540
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004814
@@ -50112,6 +52671,9 @@
xref: Reactome:R-HSA-380224 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate"
xref: RHEA:20301
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.19
+property_value: skos:exactMatch RHEA:20301
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004815
@@ -50131,6 +52693,9 @@
xref: Reactome:R-HSA-380229 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate"
xref: RHEA:19649
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.12
+property_value: skos:exactMatch RHEA:19649
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004816
@@ -50151,6 +52716,9 @@
xref: Reactome:R-HSA-380227 "asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate"
xref: RHEA:11180
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.22
+property_value: skos:exactMatch RHEA:11180
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004817
@@ -50168,6 +52736,9 @@
xref: Reactome:R-HSA-380158 "cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate"
xref: RHEA:17773
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.16
+property_value: skos:exactMatch RHEA:17773
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004818
@@ -50187,6 +52758,9 @@
xref: Reactome:R-HSA-380216 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate"
xref: RHEA:23540
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.17
+property_value: skos:exactMatch RHEA:23540
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004819
@@ -50207,6 +52781,9 @@
xref: Reactome:R-HSA-380241 "glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate"
xref: RHEA:20121
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.18
+property_value: skos:exactMatch RHEA:20121
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004820
@@ -50225,6 +52802,9 @@
xref: Reactome:R-HSA-380240 "glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate"
xref: RHEA:16013
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.14
+property_value: skos:exactMatch RHEA:16013
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004821
@@ -50241,6 +52821,9 @@
xref: Reactome:R-HSA-380234 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate"
xref: RHEA:17313
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.21
+property_value: skos:exactMatch RHEA:17313
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004822
@@ -50261,6 +52844,9 @@
xref: Reactome:R-HSA-380176 "isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate"
xref: RHEA:11060
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.5
+property_value: skos:exactMatch RHEA:11060
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004823
@@ -50281,6 +52867,9 @@
xref: Reactome:R-HSA-380200 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate"
xref: RHEA:11688
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.4
+property_value: skos:exactMatch RHEA:11688
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004824
@@ -50300,6 +52889,9 @@
xref: Reactome:R-HSA-380233 "lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate"
xref: RHEA:20792
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.6
+property_value: skos:exactMatch RHEA:20792
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004825
@@ -50319,6 +52911,9 @@
xref: Reactome:R-HSA-380157 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate"
xref: RHEA:13481
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.10
+property_value: skos:exactMatch RHEA:13481
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004826
@@ -50340,6 +52935,9 @@
xref: Reactome:R-HSA-380203 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate"
xref: RHEA:19413
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.20
+property_value: skos:exactMatch RHEA:19413
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004827
@@ -50360,6 +52958,9 @@
xref: Reactome:R-HSA-380198 "proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate"
xref: RHEA:14305
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.15
+property_value: skos:exactMatch RHEA:14305
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004828
@@ -50377,7 +52978,12 @@
xref: MetaCyc:SERINE--TRNA-LIGASE-RXN
xref: Reactome:R-HSA-379992 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate"
xref: Reactome:R-HSA-380239 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate"
+xref: RHEA:12292
+xref: RHEA:42580
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.11
+property_value: skos:narrowMatch RHEA:12292
+property_value: skos:narrowMatch RHEA:42580
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
[Term]
@@ -50400,6 +53006,9 @@
xref: Reactome:R-HSA-380201 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate"
xref: RHEA:24624
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.3
+property_value: skos:exactMatch RHEA:24624
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004830
@@ -50424,6 +53033,9 @@
xref: Reactome:R-HSA-380222 "tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate"
xref: RHEA:24080
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.2
+property_value: skos:exactMatch RHEA:24080
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004831
@@ -50449,6 +53061,9 @@
xref: Reactome:R-HSA-380170 "tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate"
xref: RHEA:10220
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.1
+property_value: skos:exactMatch RHEA:10220
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004832
@@ -50469,6 +53084,9 @@
xref: Reactome:R-HSA-380199 "valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate"
xref: RHEA:10704
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.9
+property_value: skos:exactMatch RHEA:10704
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004833
@@ -50494,6 +53112,10 @@
xref: Reactome:R-HSA-888614 "IDO2 dioxygenates L-Trp to NFK"
xref: RHEA:24536
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:broadMatch EC:1.13.11.52
+property_value: skos:exactMatch EC:1.13.11.11
+property_value: skos:exactMatch MetaCyc:RXN-8665
+property_value: skos:exactMatch RHEA:24536
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30557" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30559" xsd:anyURI
@@ -50514,6 +53136,9 @@
xref: RHEA:10532
is_a: GO:0016836 ! hydro-lyase activity
relationship: part_of GO:0000162 ! L-tryptophan biosynthetic process
+property_value: skos:exactMatch EC:4.2.1.20
+property_value: skos:exactMatch RHEA:10532
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004835
@@ -50529,6 +53154,9 @@
xref: RHEA:17605
is_a: GO:0016881 ! acid-amino acid ligase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:6.3.2.25
+property_value: skos:exactMatch RHEA:17605
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004836
@@ -50538,6 +53166,7 @@
xref: MetaCyc:RXN-14645
xref: RHEA:57132
is_a: GO:0016715 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:57132
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
[Term]
@@ -50553,6 +53182,9 @@
xref: MetaCyc:TYROSINE-DECARBOXYLASE-RXN
xref: RHEA:14345
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.25
+property_value: skos:exactMatch RHEA:14345
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004838
@@ -50582,6 +53214,8 @@
xref: RHEA:15093
xref: UM-BBD_reactionID:r0297
is_a: GO:0008793 ! aromatic-amino-acid transaminase activity
+property_value: skos:broadMatch EC:2.6.1.5
+property_value: skos:exactMatch RHEA:15093
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -50600,6 +53234,8 @@
xref: Reactome:R-HSA-8865098 "UBA6 conjugates ubiquitin to UBA6 in the cytosol"
is_a: GO:0008641 ! ubiquitin-like modifier activating enzyme activity
relationship: part_of GO:0016567 ! protein ubiquitination
+property_value: skos:exactMatch EC:6.2.1.45
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004842
@@ -50683,6 +53319,7 @@
xref: Reactome:R-HSA-3781009 "NHLRC1 mediated ubiquitination of EPM2A and PPP1RC3 associated with glycogen-GYG1"
xref: Reactome:R-HSA-3788724 "Cdh1:APC/C ubiquitinates EHMT1 and EHMT2"
xref: Reactome:R-HSA-3797226 "Defective NHLRC1 does not ubiquitinate EPM2A (laforin) and PPP1R3C (PTG) (type 2B disease)"
+xref: Reactome:R-HSA-400267 "BTRC:CUL1:SKP1 (SCF-beta-TrCP1) ubiquitinylates PER proteins"
xref: Reactome:R-HSA-4332236 "CBL neddylates TGFBR2"
xref: Reactome:R-HSA-446877 "TRAF6 is K63 poly-ubiquitinated"
xref: Reactome:R-HSA-450358 "Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation"
@@ -50709,7 +53346,7 @@
xref: Reactome:R-HSA-5691108 "SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2"
xref: Reactome:R-HSA-5693108 "TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains"
xref: Reactome:R-HSA-68712 "The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1"
-xref: Reactome:R-HSA-69598 "Ubiquitination of phosphorylated CDC25A"
+xref: Reactome:R-HSA-69598 "Ubiquitination of phosphorylated Cdc25A"
xref: Reactome:R-HSA-741386 "RIP2 induces K63-linked ubiquitination of NEMO"
xref: Reactome:R-HSA-75824 "Ubiquitination of Cyclin D1"
xref: Reactome:R-HSA-870449 "TRIM33 monoubiquitinates SMAD4"
@@ -50731,7 +53368,6 @@
xref: Reactome:R-HSA-975118 "TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex"
xref: Reactome:R-HSA-975147 "Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane"
xref: Reactome:R-HSA-9758604 "Ubiquitination of IKBKG by TRAF6"
-xref: Reactome:R-HSA-9766227 "MDM2 mediates CDH1 ubiquitination"
xref: Reactome:R-HSA-9793444 "ITCH polyubiquitinates MLKL at K50"
xref: Reactome:R-HSA-9793485 "PRKN polyubiquitinates RIPK3"
xref: Reactome:R-HSA-9793679 "LUBAC ubiquitinates RIPK1 at K627"
@@ -50748,10 +53384,6 @@
xref: Reactome:R-HSA-9834070 "PRKN ubiquitinates MOM substrates"
xref: Reactome:R-HSA-9861563 "CTLH E3 ligase ubiquitinates LDHA"
xref: Reactome:R-HSA-9861640 "CTLH E3 ligase ubiquitinates PKM-1"
-xref: Reactome:R-HSA-9929350 "Ubiquitination of CD274 by BTRC-SCF E3-ligase complex"
-xref: Reactome:R-HSA-9934753 "CBLL1 ubiquitinates CDH1"
-xref: Reactome:R-HSA-9948301 "ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit"
-xref: Reactome:R-HSA-9954721 "NEDD8-K699-CUL2:ELOB:ELOC:RBX1:KLHDC10 K48 polyubiquitinates alanine-tailed nascent peptide"
is_a: GO:0019787 ! ubiquitin-like protein transferase activity
[Term]
@@ -50840,7 +53472,9 @@
xref: Reactome:R-HSA-9653514 "USP17L2 deubiquitinates RCE1"
is_a: GO:0008234 ! cysteine-type peptidase activity
is_a: GO:0101005 ! deubiquitinase activity
+property_value: skos:exactMatch EC:3.4.19.12
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19723" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004844
@@ -50853,7 +53487,9 @@
xref: Reactome:R-HSA-110217 "Cleavage of 5-hydroxyluracil by UNG glycosylase"
xref: Reactome:R-HSA-9817512 "UNG (UNG2) and base excision repair remove uridine and 5-methylcytidine from chromatin containing histone H3.3"
is_a: GO:0097506 ! deaminated base DNA N-glycosylase activity
+property_value: skos:exactMatch EC:3.2.2.27
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25051" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004845
@@ -50874,6 +53510,9 @@
xref: MetaCyc:URACIL-PRIBOSYLTRANS-RXN
xref: RHEA:13017
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.9
+property_value: skos:exactMatch RHEA:13017
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004846
@@ -50889,6 +53528,9 @@
xref: RHEA:21368
xref: UM-BBD_reactionID:r1322
is_a: GO:0016663 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.7.3.3
+property_value: skos:exactMatch RHEA:21368
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004847
@@ -50909,6 +53551,9 @@
xref: MetaCyc:UREA-CARBOXYLASE-RXN
xref: RHEA:20896
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.6
+property_value: skos:exactMatch RHEA:20896
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004848
@@ -50922,7 +53567,10 @@
xref: MetaCyc:UREIDOGLYCOLATE-HYDROLASE-RXN
xref: RHEA:19809
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.116
+property_value: skos:exactMatch RHEA:19809
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24927" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004849
@@ -50931,12 +53579,16 @@
def: "Catalysis of the reaction: ATP + uridine = ADP + UMP." [RHEA:16825]
synonym: "uridine phosphokinase activity" EXACT []
synonym: "uridine-cytidine kinase activity" NARROW [EC:2.7.1.48]
+xref: EC:2.7.1.48
xref: MetaCyc:URIDINEKIN-RXN
xref: Reactome:R-HSA-8954327 "UCKL1 phosphorylates urindine, cytidine"
xref: RHEA:16825
is_a: GO:0019206 ! nucleoside kinase activity
relationship: part_of GO:0006222 ! UMP biosynthetic process
+property_value: skos:exactMatch RHEA:16825
+property_value: skos:narrowMatch EC:2.7.1.48
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25077" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004850
@@ -50954,6 +53606,9 @@
xref: Reactome:R-HSA-74376 "(deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)"
xref: RHEA:24388
is_a: GO:0016154 ! pyrimidine-nucleoside phosphorylase activity
+property_value: skos:exactMatch EC:2.4.2.3
+property_value: skos:exactMatch RHEA:24388
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004851
@@ -50979,7 +53634,10 @@
xref: RHEA:32459
is_a: GO:0008169 ! C-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.107
+property_value: skos:exactMatch RHEA:32459
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004852
@@ -51000,6 +53658,9 @@
xref: Reactome:R-HSA-189488 "UROS transforms HMB to URO3"
xref: RHEA:18965
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.75
+property_value: skos:exactMatch RHEA:18965
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004853
@@ -51015,6 +53676,9 @@
xref: MetaCyc:UROGENDECARBOX-RXN
xref: RHEA:19865
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.37
+property_value: skos:exactMatch RHEA:19865
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004854
@@ -51032,6 +53696,9 @@
xref: Reactome:R-HSA-9727349 "XDH dehydrogenates xanthine to form urate"
xref: RHEA:16669
is_a: GO:0016726 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.17.1.4
+property_value: skos:exactMatch RHEA:16669
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004855
@@ -51051,6 +53718,9 @@
xref: Reactome:R-HSA-9748991 "XDH oxidises 6MP to 6TU"
xref: RHEA:21132
is_a: GO:0016727 ! oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor
+property_value: skos:exactMatch EC:1.17.3.2
+property_value: skos:exactMatch RHEA:21132
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004856
@@ -51068,8 +53738,11 @@
xref: RHEA:10964
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.17
+property_value: skos:exactMatch RHEA:10964
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26853" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28622" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0004857
@@ -51079,8 +53752,6 @@
def: "A molecular function regulator that reduces a catalytic activity." [GOC:ai, GOC:ebc]
comment: This term should only be used in cases when the regulator directly interacts with the enzyme, but does not result in a covalent modification.
synonym: "metalloenzyme inhibitor activity" NARROW []
-xref: Reactome:R-HSA-1474158 "GCHFR binds to GCH1 and negatively regulates its activity"
-xref: Reactome:R-HSA-1614336 "SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases"
is_a: GO:0030234 ! enzyme regulator activity
is_a: GO:0140678 ! molecular function inhibitor activity
relationship: negatively_regulates GO:0003824 ! catalytic activity
@@ -51099,7 +53770,7 @@
namespace: molecular_function
def: "Binds to and stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid." [GOC:ai, GOC:rl]
is_a: GO:0055102 ! lipase inhibitor activity
-relationship: negatively_regulates GO:0004620 ! phospholipase activity
+relationship: negatively_regulates GO:0004620 ! glycerophospholipase activity
[Term]
id: GO:0004860
@@ -51323,10 +53994,6 @@
synonym: "vitamin A receptor activity" NARROW []
synonym: "vitamin D receptor activity" NARROW []
synonym: "vitamin D3 receptor activity" NARROW [GOC:bf, Wikipedia:Calcitriol_receptor]
-xref: Reactome:R-HSA-400143 "Fatty acid ligands activate PPARA"
-xref: Reactome:R-HSA-8936849 "AHR:2xHSP90:AIP:PTGES3 binds TCDD"
-xref: Reactome:R-HSA-8937169 "AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm"
-xref: Reactome:R-HSA-8937191 "AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates"
is_a: GO:0000981 ! DNA-binding transcription factor activity, RNA polymerase II-specific
is_a: GO:0038023 ! signaling receptor activity
is_a: GO:0098531 ! ligand-modulated transcription factor activity
@@ -51719,7 +54386,6 @@
synonym: "frizzled receptor activity" EXACT []
is_obsolete: true
replaced_by: GO:0042813
-consider: GO:0016055
[Term]
id: GO:0004929
@@ -51730,7 +54396,6 @@
synonym: "frizzled-2 receptor activity" EXACT []
is_obsolete: true
replaced_by: GO:0042813
-consider: GO:0007223
[Term]
id: GO:0004930
@@ -51779,7 +54444,6 @@
synonym: "purinoceptor" BROAD []
synonym: "purinoreceptor" BROAD []
xref: Reactome:R-HSA-877187 "P2X7 mediates loss of intracellular K+"
-xref: Reactome:R-HSA-9905964 "P2RX7 in ATP:P2RX7:PANX1 transports cations from the extracellular region to the cytosol"
is_a: GO:0005231 ! excitatory extracellular ligand-gated monoatomic ion channel activity
is_a: GO:0035381 ! ATP-gated ion channel activity
is_a: GO:0099094 ! ligand-gated monoatomic cation channel activity
@@ -52073,7 +54737,6 @@
name: glucagon receptor activity
namespace: molecular_function
def: "Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:mah, GOC:signaling, PMID:22438981]
-xref: Reactome:R-HSA-163625 "Glucagon binds to Glucagon receptor"
is_a: GO:0008528 ! G protein-coupled peptide receptor activity
relationship: part_of GO:0071377 ! cellular response to glucagon stimulus
@@ -52399,6 +55062,7 @@
def: "Combining with a GPI-anchored ephrin to initiate a change in cell activity." [GOC:mah, PMID:9530499]
synonym: "GPI-linked Eph receptor activity" EXACT []
is_a: GO:0005003 ! ephrin receptor activity
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -52408,6 +55072,7 @@
def: "Combining with a transmembrane ephrin to initiate a change in cell activity." [GOC:mah, PMID:9530499]
synonym: "transmembrane-Eph receptor activity" EXACT []
is_a: GO:0005003 ! ephrin receptor activity
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -52424,8 +55089,10 @@
is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity
relationship: has_part GO:0048408 ! epidermal growth factor binding
relationship: part_of GO:0007173 ! epidermal growth factor receptor signaling pathway
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23056" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0005007
@@ -52440,6 +55107,7 @@
is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity
relationship: has_part GO:0017134 ! fibroblast growth factor binding
relationship: part_of GO:0008543 ! fibroblast growth factor receptor signaling pathway
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23056" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -52455,8 +55123,10 @@
is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity
relationship: has_part GO:0036458 ! hepatocyte growth factor binding
relationship: part_of GO:0048012 ! hepatocyte growth factor receptor signaling pathway
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23056" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0005009
@@ -52469,8 +55139,10 @@
is_a: GO:0016500 ! protein-hormone receptor activity
relationship: has_part GO:0043559 ! insulin binding
relationship: part_of GO:0008286 ! insulin receptor signaling pathway
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23056" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0005010
@@ -52484,6 +55156,7 @@
is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity
relationship: has_part GO:0005520 ! insulin-like growth factor binding
relationship: part_of GO:0048009 ! insulin-like growth factor receptor signaling pathway
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23056" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -52498,6 +55171,7 @@
synonym: "macrophage colony stimulating factor receptor activity" EXACT []
is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity
relationship: part_of GO:0038145 ! macrophage colony-stimulating factor signaling pathway
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -52586,6 +55260,7 @@
synonym: "PDGF alpha-receptor activity" EXACT []
is_a: GO:0005017 ! platelet-derived growth factor receptor activity
relationship: part_of GO:0035790 ! platelet-derived growth factor receptor-alpha signaling pathway
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -52597,6 +55272,7 @@
synonym: "PDGF beta-receptor activity" EXACT []
is_a: GO:0005017 ! platelet-derived growth factor receptor activity
relationship: part_of GO:0035791 ! platelet-derived growth factor receptor-beta signaling pathway
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -52610,7 +55286,9 @@
synonym: "SCF receptor activity" EXACT [PR:000009345]
is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity
relationship: part_of GO:0038109 ! Kit signaling pathway
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0005021
@@ -52636,6 +55314,7 @@
is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity
relationship: has_part GO:0038085 ! vascular endothelial growth factor binding
relationship: part_of GO:0038084 ! vascular endothelial growth factor signaling pathway
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23056" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -52651,7 +55330,9 @@
synonym: "TGFbetaR" EXACT []
synonym: "transforming growth factor beta-activated receptor activity" EXACT []
is_a: GO:0004675 ! transmembrane receptor protein serine/threonine kinase activity
+property_value: skos:broadMatch EC:2.7.11.30
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23056" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0005025
@@ -52663,6 +55344,7 @@
synonym: "type I TGFbeta receptor activity" EXACT []
synonym: "type I transforming growth factor beta receptor activity" EXACT []
is_a: GO:0005024 ! transforming growth factor beta receptor activity
+property_value: skos:broadMatch EC:2.7.11.30
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -52677,6 +55359,7 @@
xref: Reactome:R-HSA-170843 "TGFBR2 phosphorylates TGFBR1"
is_a: GO:0005024 ! transforming growth factor beta receptor activity
relationship: has_part GO:0050431 ! transforming growth factor beta binding
+property_value: skos:broadMatch EC:2.7.11.30
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -53231,7 +55914,6 @@
xref: Reactome:R-HSA-379044 "Liganded Gs-activating GPCR acts as a GEF for Gs"
xref: Reactome:R-HSA-379048 "Liganded Gq/11-activating GPCRs act as GEFs for Gq/11"
xref: Reactome:R-HSA-380073 "Liganded Gi-activating GPCR acts as a GEF for Gi"
-xref: Reactome:R-HSA-381727 "RAP1A exchanges GDP for GTP"
xref: Reactome:R-HSA-389348 "Activation of Rac1 by pVav1"
xref: Reactome:R-HSA-389350 "Activation of Cdc42 by pVav1"
xref: Reactome:R-HSA-392054 "NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras"
@@ -53247,7 +55929,6 @@
xref: Reactome:R-HSA-3965444 "WNT:FZD complex promotes G-protein nucleotide exchange"
xref: Reactome:R-HSA-399938 "Activation of Rac1 by FARP2"
xref: Reactome:R-HSA-399995 "Muscarinic Acetylcholine Receptor M3 activates Gq"
-xref: Reactome:R-HSA-400037 "Gi,Go Heterotrimeric G-protein complex dissociates"
xref: Reactome:R-HSA-400092 "Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins"
xref: Reactome:R-HSA-4093336 "p-TIAM1 exchanges GTP for GDP on RAC1, activating it"
xref: Reactome:R-HSA-416530 "FFAR1:FFAR1 ligands activate Gq"
@@ -54033,8 +56714,7 @@
synonym: "EGFR activating ligand activity" EXACT []
synonym: "epidermal growth factor receptor activating ligand activity" EXACT []
is_obsolete: true
-replaced_by: GO:0005154
-consider: GO:0030297
+replaced_by: GO:0048018
[Term]
id: GO:0005156
@@ -54046,9 +56726,7 @@
synonym: "EGFR inhibiting ligand activity" EXACT []
synonym: "epidermal growth factor receptor inhibiting ligand activity" EXACT []
is_obsolete: true
-replaced_by: GO:0005154
-consider: GO:0007175
-consider: GO:0030293
+replaced_by: GO:0141069
[Term]
id: GO:0005157
@@ -54869,7 +57547,6 @@
xref: Reactome:R-HSA-5577213 "LTCC multimer transports Ca2+ from extracellular region to cytosol"
xref: Reactome:R-HSA-9701055 "TRPA1 tetramer transports Ca2+ from extracellular region to cytosol"
xref: Reactome:R-HSA-9701141 "TRPV1 transports Ca2+ from extracellular region to cytosol"
-xref: Reactome:R-HSA-9905934 "CaV3.2 (CACNA1H:CACNA2D1:CACNB1,2,3:CACNG7) transports calcium from the extracellular region to the cytosol"
is_a: GO:0005262 ! calcium channel activity
is_a: GO:0022843 ! voltage-gated monoatomic cation channel activity
@@ -54974,6 +57651,7 @@
xref: Reactome:R-HSA-975449 "GABRR pentamers:GABA transports extracellular Cl- to cytosol"
is_a: GO:0005253 ! monoatomic anion channel activity
is_a: GO:0015108 ! chloride transmembrane transporter activity
+property_value: skos:broadMatch RHEA:29823
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
[Term]
@@ -54994,8 +57672,11 @@
is_a: GO:0099095 ! ligand-gated monoatomic anion channel activity
is_a: GO:0099142 ! intracellularly ATP-gated ion channel activity
is_a: GO:0120544 ! polypeptide conformation or assembly isomerase activity
+property_value: skos:exactMatch EC:5.6.1.6
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14402" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29690" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0005261
@@ -55007,9 +57688,12 @@
synonym: "cation channel activity" BROAD []
synonym: "cation diffusion facilitator activity" EXACT []
synonym: "non-selective cation channel activity" NARROW []
+xref: Reactome:R-HSA-1168376 "STIM1 oligomerizes"
xref: Reactome:R-HSA-1296043 "Activation of HCN channels"
+xref: Reactome:R-HSA-169683 "IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol"
xref: Reactome:R-HSA-2089943 "TRPC1 translocates calcium from the extracellular region to the cytosol"
xref: Reactome:R-HSA-426223 "Cation influx mediated by TRPC3/6/7"
+xref: Reactome:R-HSA-4420052 "Decreasing cGMP concentration promotes intracellular Ca2+ release in response to WNT"
xref: Reactome:R-HSA-9706720 "SARS-CoV-1 E transports Ca2+"
xref: Reactome:R-HSA-9712190 "cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol"
xref: Reactome:R-HSA-9754616 "SARS-CoV-2 E pentamer transports Ca2+"
@@ -55033,6 +57717,7 @@
xref: Reactome:R-HSA-9858800 "TRPV4 tetramer:CALM1:Ca2+ transports calcium ions (Ca2+) from the extracellular region to the cytosol"
is_a: GO:0005261 ! monoatomic cation channel activity
is_a: GO:0015085 ! calcium ion transmembrane transporter activity
+property_value: skos:broadMatch RHEA:29671
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
[Term]
@@ -55054,6 +57739,7 @@
xref: Reactome:R-HSA-5578910 "KCNK dimers transport K+ from cytosol to extracellular region"
is_a: GO:0005261 ! monoatomic cation channel activity
is_a: GO:0015079 ! potassium ion transmembrane transporter activity
+property_value: skos:broadMatch RHEA:29463
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
[Term]
@@ -55069,6 +57755,7 @@
xref: Reactome:R-HSA-9717396 "SCN2A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol"
is_a: GO:0005261 ! monoatomic cation channel activity
is_a: GO:0015081 ! sodium ion transmembrane transporter activity
+property_value: skos:broadMatch RHEA:34963
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
[Term]
@@ -55081,7 +57768,6 @@
synonym: "allantoin uptake transmembrane transporter activity" NARROW []
synonym: "allantoin/allantoate transporter" BROAD []
is_a: GO:0015295 ! solute:proton symporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
relationship: part_of GO:0015720 ! allantoin transport
[Term]
@@ -55263,7 +57949,9 @@
is_a: GO:0005283 ! amino acid:sodium symporter activity
is_a: GO:0005343 ! organic acid:sodium symporter activity
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
+property_value: skos:exactMatch RHEA:28967
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0005300
@@ -55324,7 +58012,9 @@
xref: RHEA:76443
is_a: GO:0015220 ! choline transmembrane transporter activity
is_a: GO:0015370 ! solute:sodium symporter activity
+property_value: skos:exactMatch RHEA:76443
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0005308
@@ -55448,7 +58138,6 @@
xref: Reactome:R-HSA-1369028 "ABCAs mediate lipid efflux"
xref: Reactome:R-HSA-1369052 "ABCAs mediate lipid influx"
xref: Reactome:R-HSA-174786 "ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex"
-xref: Reactome:R-HSA-5334794 "FABPs bind LCFAs"
xref: Reactome:R-HSA-5682285 "ABCA12 transports lipids from cytosol to extracellular region"
xref: Reactome:R-HSA-5682311 "Defective ABCA12 does not transport lipids from cytosol to extracellular region"
xref: Reactome:R-HSA-5683672 "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body"
@@ -55457,7 +58146,6 @@
xref: Reactome:R-HSA-6801250 "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane"
xref: Reactome:R-HSA-8848053 "ABCA5 transports CHOL from lysosomal lumen to cytosol"
xref: Reactome:R-HSA-8866329 "MTTP lipidates APOB-100, forming a pre-VLDL"
-xref: Reactome:R-HSA-8873834 "STARD10 transports PC from ER membrane to lamellar body membrane"
is_a: GO:0005215 ! transporter activity
relationship: part_of GO:0006869 ! lipid transport
@@ -55514,18 +58202,19 @@
def: "Enables the transfer of a long-chain fatty acid from one side of a membrane to the other. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons." [ISBN:0198506732]
comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
synonym: "long-chain fatty acid transporter activity" RELATED []
-xref: Reactome:R-HSA-2026996 "FABP1 transports fatty acids into the nucleus"
xref: Reactome:R-HSA-2046087 "Translocation of tetracosahexaenoyl-CoA to peroxisomes"
xref: Reactome:R-HSA-2046093 "Translocation of tetracosapentaenoyl-CoA to peroxisomes"
xref: Reactome:R-HSA-382575 "ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix"
-xref: Reactome:R-HSA-434381 "CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol"
+xref: Reactome:R-HSA-434381 "CD36 (FAT) translocates palmitate from the extracellular region to the cytosol"
xref: Reactome:R-HSA-5684043 "Defective ABCD1 does not transfer LCFAs from cytosol to peroxisomal matrix"
xref: RHEA:39283
is_a: GO:0015245 ! fatty acid transmembrane transporter activity
relationship: part_of GO:0015909 ! long-chain fatty acid transport
+property_value: skos:exactMatch RHEA:39283
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14793" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26996" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0005326
@@ -55556,9 +58245,13 @@
synonym: "dopamine transmembrane transporter activity" EXACT []
synonym: "dopamine:sodium:chloride symporter activity" EXACT []
synonym: "sodium/dopamine symporter activity" EXACT []
+xref: RHEA:70919
+xref: RHEA:70931
is_a: GO:0008504 ! monoamine transmembrane transporter activity
is_a: GO:0015378 ! sodium:chloride symporter activity
relationship: part_of GO:0090494 ! dopamine uptake
+property_value: skos:narrowMatch RHEA:70919
+property_value: skos:narrowMatch RHEA:70931
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16054" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
@@ -55575,11 +58268,15 @@
synonym: "gamma-aminobutyric acid:sodium symporter activity" EXACT []
synonym: "sodium/chloride-dependent GABA transporter activity" BROAD []
xref: Reactome:R-HSA-444007 "GAT1-3 mediate Na+/Cl- dependent GABA transport"
+xref: RHEA:70687
+xref: RHEA:70731
xref: TC:2.A.22.3.2
is_a: GO:0005283 ! amino acid:sodium symporter activity
is_a: GO:0015185 ! gamma-aminobutyric acid transmembrane transporter activity
is_a: GO:0015378 ! sodium:chloride symporter activity
is_a: GO:0140161 ! monocarboxylate:sodium symporter activity
+property_value: skos:narrowMatch RHEA:70687
+property_value: skos:narrowMatch RHEA:70731
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23299" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
@@ -55594,7 +58291,7 @@
synonym: "norepinephrine transmembrane transporter activity" EXACT []
synonym: "norepinephrine:sodium:chloride symporter activity" EXACT []
synonym: "sodium/norepinephrine symporter activity" EXACT []
-xref: Reactome:R-HSA-443997 "SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol"
+xref: Reactome:R-HSA-443997 "SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol"
xref: Reactome:R-HSA-5659764 "Defective SLC6A2 does not cotransport NAd, Na+ from extracellular region to cytosol"
xref: Wikipedia:Norepinephrine_transporter
is_a: GO:0008504 ! monoamine transmembrane transporter activity
@@ -55617,7 +58314,9 @@
is_a: GO:0008504 ! monoamine transmembrane transporter activity
is_a: GO:0015378 ! sodium:chloride symporter activity
relationship: part_of GO:0051610 ! serotonin uptake
+property_value: skos:exactMatch RHEA:51196
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23840" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0005337
@@ -55809,6 +58508,8 @@
synonym: "glucose permease activity" EXACT []
synonym: "glucose transmembrane transporter activity" EXACT []
synonym: "lactose/glucose efflux transporter activity" NARROW []
+xref: Reactome:R-HSA-499981 "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2"
+xref: Reactome:R-HSA-5653873 "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27326" xsd:anyURI
is_obsolete: true
replaced_by: GO:0055056
@@ -55911,11 +58612,6 @@
namespace: molecular_function
def: "Enables the transfer of myo-inositol from one side of a membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms." [GOC:ai]
synonym: "vitamin Bh transporter activity" EXACT []
-xref: Reactome:R-HSA-1855155 "I(1,3,4,5,6)P5 transports from the ER lumen to the cytosol"
-xref: Reactome:R-HSA-1855164 "IP6 transports from the cytosol to the ER lumen"
-xref: Reactome:R-HSA-1855186 "I(1,3,4,5)P4 transports from the cytosol to the ER lumen"
-xref: Reactome:R-HSA-1855195 "I(1,3,4,5,6)P5 transports from the cytosol to the ER lumen"
-xref: Reactome:R-HSA-1855217 "I(1,4,5)P3 transports from the ER lumen to the cytosol"
is_a: GO:0015166 ! polyol transmembrane transporter activity
relationship: part_of GO:0015798 ! myo-inositol transport
@@ -55930,6 +58626,8 @@
xref: RHEA:60364
is_a: GO:0005365 ! myo-inositol transmembrane transporter activity
is_a: GO:0015295 ! solute:proton symporter activity
+property_value: skos:exactMatch RHEA:60364
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0005367
@@ -56090,7 +58788,6 @@
xref: Reactome:R-HSA-442422 "SLC39A1-4 transports Zn2+ from extracellular region to cytosol"
xref: Reactome:R-HSA-5654125 "Defective SLC39A4 does not transport Zn2+ from extracellular region to cytosol"
xref: Reactome:R-HSA-9820566 "ZnT5 transports zinc into the golgi apparatus"
-xref: Reactome:R-HSA-9928035 "ZnuABC transports Zn2+ to cytosol"
is_a: GO:0046915 ! transition metal ion transmembrane transporter activity
relationship: part_of GO:0071577 ! zinc ion transmembrane transport
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
@@ -56124,7 +58821,10 @@
is_a: GO:0015085 ! calcium ion transmembrane transporter activity
is_a: GO:0015662 ! P-type ion transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
+property_value: skos:exactMatch EC:7.2.2.10
+property_value: skos:exactMatch RHEA:18105
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0005391
@@ -56152,7 +58852,10 @@
is_a: GO:0008554 ! P-type sodium transporter activity
is_a: GO:0008556 ! P-type potassium transmembrane transporter activity
relationship: part_of GO:0010248 ! establishment or maintenance of transmembrane electrochemical gradient
+property_value: skos:exactMatch EC:7.2.2.13
+property_value: skos:exactMatch RHEA:18353
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17289" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0005395
@@ -56209,9 +58912,13 @@
xref: Reactome:R-HSA-5656356 "Defective SLC5A1 does not cotransport Glc and Na+"
xref: Reactome:R-HSA-5658163 "Defective SLC5A2 does not cotransport Glc and Na+ from extracellular region to cytosol"
xref: Reactome:R-HSA-8932955 "SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol"
+xref: RHEA:70495
+xref: RHEA:70571
is_a: GO:0005402 ! carbohydrate:monoatomic cation symporter activity
is_a: GO:0015370 ! solute:sodium symporter activity
is_a: GO:0055056 ! D-glucose transmembrane transporter activity
+property_value: skos:narrowMatch RHEA:70495
+property_value: skos:narrowMatch RHEA:70571
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
[Term]
@@ -56282,6 +58989,8 @@
xref: RHEA:29255
is_a: GO:0015081 ! sodium ion transmembrane transporter activity
is_a: GO:0015368 ! calcium:monoatomic cation antiporter activity
+property_value: skos:exactMatch RHEA:29255
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0005436
@@ -56301,9 +59010,13 @@
xref: Reactome:R-HSA-5651697 "Defective SLC34A2 does not cotransport Pi, 3Na+"
xref: Reactome:R-HSA-5651971 "Defective SLC34A3 does not cotransport Pi, 2Na+"
xref: Reactome:R-HSA-5687585 "Defective SLC34A2 does not cotransport HPO4(2-), 3Na+ from extracellular region to cytosol"
+xref: RHEA:71255
+xref: RHEA:71259
xref: TC:2.A.1.14.6
is_a: GO:0005315 ! phosphate transmembrane transporter activity
is_a: GO:0015370 ! solute:sodium symporter activity
+property_value: skos:narrowMatch RHEA:71255
+property_value: skos:narrowMatch RHEA:71259
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18577" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23132" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27012" xsd:anyURI
@@ -56447,7 +59160,9 @@
is_a: GO:0015138 ! fumarate transmembrane transporter activity
is_a: GO:0015141 ! succinate transmembrane transporter activity
is_a: GO:0015297 ! antiporter activity
+property_value: skos:exactMatch RHEA:29323
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0005471
@@ -56464,7 +59179,9 @@
is_a: GO:0005347 ! ATP transmembrane transporter activity
is_a: GO:0015217 ! ADP transmembrane transporter activity
is_a: GO:0015297 ! antiporter activity
+property_value: skos:exactMatch RHEA:34999
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0005476
@@ -56873,7 +59590,6 @@
def: "Binding to a 23-membered macrolide lactone FK506." [GOC:jl]
synonym: "FK506-sensitive peptidyl-prolyl cis-trans isomerase" RELATED []
is_a: GO:0005527 ! macrolide binding
-is_a: GO:0033218 ! amide binding
[Term]
id: GO:0005530
@@ -56984,7 +59700,6 @@
synonym: "vitamin M binding" EXACT []
is_a: GO:0019842 ! vitamin binding
is_a: GO:0031406 ! carboxylic acid binding
-is_a: GO:0033218 ! amide binding
is_a: GO:0072341 ! modified amino acid binding
is_a: GO:1901363 ! heterocyclic compound binding
@@ -57360,9 +60075,9 @@
def: "Any triple helical collagen trimer that forms fibrils." [PMID:21421911]
is_a: GO:0005581 ! collagen trimer
intersection_of: GO:0005581 ! collagen trimer
-intersection_of: part_of GO:0098643 ! fibrillar collagen
+intersection_of: part_of GO:0098643 ! fibrillar collagen complex
disjoint_from: GO:0030936 ! transmembrane collagen trimer
-relationship: part_of GO:0098643 ! fibrillar collagen
+relationship: part_of GO:0098643 ! fibrillar collagen complex
[Term]
id: GO:0005584
@@ -57418,7 +60133,7 @@
namespace: cellular_component
def: "A collagen homotrimer of alpha1(VII) chains; type VII collagen triple helices form antiparallel dimer, which in turn associate laterally to form anchoring fibrils that connect type IV collagen in the basal lamina to plaques in the underlying connective tissue. It binds laminin." [PMID:19693541]
is_a: GO:0140158 ! von-Willerbrand-factor-A-domain-rich collagen trimer
-relationship: part_of GO:0098652 ! collagen type VII anchoring fibril
+relationship: part_of GO:0098648 ! collagen anchoring fibril
[Term]
id: GO:0005591
@@ -57426,9 +60141,9 @@
namespace: cellular_component
def: "A collagen heterotrimer containing type VIII alpha chains; [alpha1(VIII)2]alpha2(VIII) and alpha1(VIII)[alpha2(VIII)]2 trimers have been observed; type VIII collagen triple helices associate to form regular hexagonal nets." [PMID:21421911]
is_a: GO:0098642 ! network-forming collagen trimer
-relationship: part_of GO:0098646 ! interstitial hexagonal collagen network
relationship: part_of GO:0140155 ! hexagonal collagen network of basement membrane
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30148" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31070" xsd:anyURI
[Term]
id: GO:0005592
@@ -57548,63 +60263,77 @@
[Term]
id: GO:0005606
-name: laminin-1 complex
+name: laminin-111 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354]
+def: "A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
+synonym: "laminin-1 complex" EXACT []
synonym: "laminin-111 complex" EXACT [GOC:dph, PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
[Term]
id: GO:0005607
-name: laminin-2 complex
+name: laminin-211 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354]
+def: "A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
+synonym: "laminin-2 complex" EXACT []
synonym: "laminin-211 complex" EXACT [GOC:dph, PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
[Term]
id: GO:0005608
-name: laminin-3 complex
+name: laminin-121 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains." [MEDLINE:95005761]
+def: "A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
synonym: "laminin-121 complex" EXACT [GOC:dph, PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+synonym: "laminin-3 complex" EXACT []
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
[Term]
id: GO:0005609
-name: laminin-4 complex
+name: laminin-221 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354]
+def: "A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
synonym: "laminin-221 complex" EXACT [GOC:dph, PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+synonym: "laminin-4 complex" EXACT []
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
[Term]
id: GO:0005610
-name: laminin-5 complex
+name: laminin-332 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains." [GOC:jl, PMID:10842354]
+def: "A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
synonym: "laminin-332 complex" NARROW [GOC:dph, PMID:15979864]
synonym: "laminin-3A32 complex" EXACT [PMID:15979864]
+synonym: "laminin-5 complex" BROAD []
synonym: "laminin-5A complex" EXACT [PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
[Term]
id: GO:0005611
-name: laminin-6 complex
+name: laminin-311 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354]
+def: "A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
synonym: "laminin-311 complex" EXACT [GOC:dph, PMID:15979864]
+synonym: "laminin-6 complex" EXACT []
synonym: "laminin-6A complex" EXACT [PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
[Term]
id: GO:0005612
-name: laminin-7 complex
+name: laminin-321 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354]
+def: "A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
synonym: "laminin-321 complex" NARROW [GOC:dph, PMID:15979864]
+synonym: "laminin-7 complex" EXACT []
synonym: "laminin-7A" EXACT [PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
[Term]
id: GO:0005613
@@ -61225,9 +63954,11 @@
synonym: "glycogen biosynthesis" EXACT []
synonym: "glycogen formation" EXACT []
synonym: "glycogen synthesis" EXACT []
+xref: MetaCyc:PWY-7900
xref: Reactome:R-HSA-3322077 "Glycogen synthesis"
is_a: GO:0005977 ! glycogen metabolic process
is_a: GO:0009250 ! glucan biosynthetic process
+property_value: skos:narrowMatch MetaCyc:PWY-7900
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28968" xsd:anyURI
@@ -61256,9 +63987,11 @@
synonym: "glycogen catabolism" EXACT []
synonym: "glycogen degradation" EXACT []
synonym: "glycogenolysis" EXACT [GOC:sl]
+xref: MetaCyc:PWY-7662
xref: Reactome:R-HSA-70221 "Glycogen breakdown (glycogenolysis)"
is_a: GO:0005977 ! glycogen metabolic process
is_a: GO:0009251 ! glucan catabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-7662
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -61395,8 +64128,16 @@
synonym: "trehalose biosynthesis" EXACT []
synonym: "trehalose formation" EXACT []
synonym: "trehalose synthesis" EXACT []
+xref: MetaCyc:PWY-2661
+xref: MetaCyc:PWY-881
+xref: MetaCyc:TREHALOSESYN-PWY
+xref: MetaCyc:TRESYN-PWY
is_a: GO:0005991 ! trehalose metabolic process
is_a: GO:0046351 ! disaccharide biosynthetic process
+property_value: skos:narrowMatch MetaCyc:PWY-2661
+property_value: skos:narrowMatch MetaCyc:PWY-881
+property_value: skos:narrowMatch MetaCyc:TREHALOSESYN-PWY
+property_value: skos:narrowMatch MetaCyc:TRESYN-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27083" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27111" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -61413,8 +64154,20 @@
synonym: "trehalose breakdown" EXACT []
synonym: "trehalose catabolism" EXACT []
synonym: "trehalose degradation" EXACT []
+xref: MetaCyc:PWY-2721
+xref: MetaCyc:PWY-2722
+xref: MetaCyc:PWY-2723
+xref: MetaCyc:PWY0-1182
+xref: MetaCyc:PWY0-1466
+xref: MetaCyc:TREDEGLOW-PWY
is_a: GO:0005991 ! trehalose metabolic process
is_a: GO:0046352 ! disaccharide catabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-2721
+property_value: skos:narrowMatch MetaCyc:PWY-2722
+property_value: skos:narrowMatch MetaCyc:PWY-2723
+property_value: skos:narrowMatch MetaCyc:PWY0-1182
+property_value: skos:narrowMatch MetaCyc:PWY0-1466
+property_value: skos:narrowMatch MetaCyc:TREDEGLOW-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27082" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27111" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -61827,9 +64580,15 @@
synonym: "chitin breakdown" EXACT []
synonym: "chitin catabolism" EXACT []
synonym: "chitin degradation" EXACT []
+xref: MetaCyc:PWY-6902
+xref: MetaCyc:PWY-7118
+xref: MetaCyc:PWY-7822
is_a: GO:0006026 ! aminoglycan catabolic process
is_a: GO:0006030 ! chitin metabolic process
is_a: GO:1901072 ! glucosamine-containing compound catabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-6902
+property_value: skos:narrowMatch MetaCyc:PWY-7118
+property_value: skos:narrowMatch MetaCyc:PWY-7822
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -61994,8 +64753,12 @@
synonym: "N-acetylglucosamine breakdown" EXACT []
synonym: "N-acetylglucosamine catabolism" EXACT []
synonym: "N-acetylglucosamine degradation" EXACT []
+xref: MetaCyc:GLUAMCAT-PWY
+xref: MetaCyc:PWY-6517
is_a: GO:0006044 ! N-acetylglucosamine metabolic process
is_a: GO:1901072 ! glucosamine-containing compound catabolic process
+property_value: skos:narrowMatch MetaCyc:GLUAMCAT-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-6517
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -62019,10 +64782,14 @@
synonym: "UDP-N-acetylglucosamine biosynthesis" EXACT []
synonym: "UDP-N-acetylglucosamine formation" EXACT []
synonym: "UDP-N-acetylglucosamine synthesis" EXACT []
+xref: MetaCyc:UDPNACETYLGALSYN-PWY
+xref: MetaCyc:UDPNAGSYN-PWY
xref: Reactome:R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine"
is_a: GO:0006047 ! UDP-N-acetylglucosamine metabolic process
is_a: GO:0009226 ! nucleotide-sugar biosynthetic process
is_a: GO:0046349 ! amino sugar biosynthetic process
+property_value: skos:narrowMatch MetaCyc:UDPNACETYLGALSYN-PWY
+property_value: skos:narrowMatch MetaCyc:UDPNAGSYN-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -62089,7 +64856,6 @@
synonym: "sialic acid metabolism" BROAD []
is_a: GO:0006040 ! amino sugar metabolic process
is_a: GO:0019752 ! carboxylic acid metabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0006055
@@ -62100,8 +64866,12 @@
synonym: "CMP-N-acetylneuraminate biosynthesis" EXACT []
synonym: "CMP-N-acetylneuraminate formation" EXACT []
synonym: "CMP-N-acetylneuraminate synthesis" EXACT []
+xref: MetaCyc:PWY-6138
+xref: MetaCyc:PWY-6139
is_a: GO:0009226 ! nucleotide-sugar biosynthetic process
is_a: GO:0046381 ! CMP-N-acetylneuraminate metabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-6138
+property_value: skos:narrowMatch MetaCyc:PWY-6139
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28431" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -62216,9 +64986,13 @@
synonym: "UDP-glucuronate biosynthesis" EXACT []
synonym: "UDP-glucuronate formation" EXACT []
synonym: "UDP-glucuronate synthesis" EXACT []
+xref: MetaCyc:PWY-4841
+xref: MetaCyc:PWY-7346
is_a: GO:0009226 ! nucleotide-sugar biosynthetic process
is_a: GO:0046394 ! carboxylic acid biosynthetic process
is_a: GO:0046398 ! UDP-glucuronate metabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-4841
+property_value: skos:narrowMatch MetaCyc:PWY-7346
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -62542,10 +65316,16 @@
def: "The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [MetaCyc:GLUCONEO-PWY]
synonym: "glucose biosynthesis" EXACT []
synonym: "glucose biosynthetic process" EXACT []
+xref: MetaCyc:GLUCONEO-PWY
+xref: MetaCyc:PWY-6142
+xref: MetaCyc:PWY66-399
xref: Reactome:R-HSA-70263 "Gluconeogenesis"
xref: Wikipedia:Gluconeogenesis
is_a: GO:0006006 ! glucose metabolic process
is_a: GO:0019319 ! hexose biosynthetic process
+property_value: skos:narrowMatch MetaCyc:GLUCONEO-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-6142
+property_value: skos:narrowMatch MetaCyc:PWY66-399
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28953" xsd:anyURI
[Term]
@@ -62615,10 +65395,28 @@
synonym: "Krebs cycle" EXACT []
synonym: "oxidative TCA cycle" EXACT []
synonym: "TCA cycle" EXACT []
+xref: MetaCyc:P105-PWY
+xref: MetaCyc:PWY-5690
+xref: MetaCyc:PWY-5913
+xref: MetaCyc:PWY-6969
+xref: MetaCyc:PWY-7254
+xref: MetaCyc:PWY66-398
+xref: MetaCyc:REDCITCYC
+xref: MetaCyc:TCA
+xref: MetaCyc:TCA-1
xref: Reactome:R-HSA-71403 "Citric acid cycle (TCA cycle)"
xref: Wikipedia:Tricarboxylic_acid_cycle
is_a: GO:0044238 ! primary metabolic process
relationship: part_of GO:0009060 ! aerobic respiration
+property_value: skos:narrowMatch MetaCyc:P105-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-5690
+property_value: skos:narrowMatch MetaCyc:PWY-5913
+property_value: skos:narrowMatch MetaCyc:PWY-6969
+property_value: skos:narrowMatch MetaCyc:PWY-7254
+property_value: skos:narrowMatch MetaCyc:PWY66-398
+property_value: skos:narrowMatch MetaCyc:REDCITCYC
+property_value: skos:narrowMatch MetaCyc:TCA
+property_value: skos:narrowMatch MetaCyc:TCA-1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28429" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -62778,7 +65576,8 @@
name: fermentation
namespace: biological_process
def: "The metabolic process that uses oxidation-reduction reactions of organic compounds and substrate-level phosphorylation for the generation of adenosine triphosphate (ATP), without consuming oxygen and is independent of electron transport chains." [PMID:25617754, PMID:38821505]
-comment: PMID:38821505 mentions exceptions regarding organic compounds and ETC. Fermentation sub-processes exclude glycolysis to prevent redundancy with the glycolytic pathway.
+comment: PMID:38821505 mentions exceptions regarding organic compounds and electron transport chain. Fermentation sub-processes exclude glycolysis to prevent redundancy with the glycolytic pathway.
+subset: gocheck_do_not_annotate
subset: goslim_pir
xref: MetaCyc:Fermentation
xref: Wikipedia:Fermentation_(biochemistry)
@@ -63211,8 +66010,10 @@
synonym: "adenosine catabolism" EXACT []
synonym: "adenosine degradation" EXACT []
synonym: "adenosine phosphorolysis" RELATED []
+xref: MetaCyc:SALVADEHYPOX-PWY
is_a: GO:0046085 ! adenosine metabolic process
is_a: GO:0046130 ! purine ribonucleoside catabolic process
+property_value: skos:narrowMatch MetaCyc:SALVADEHYPOX-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -66860,10 +69661,9 @@
synonym: "ATP-dependent peptidolysis" EXACT []
synonym: "ATP-dependent proteolysis" EXACT []
is_obsolete: true
-replaced_by: GO:0004176
consider: GO:0006508
consider: GO:0016485
-consider: GO:0051603
+consider: GO:0030163
[Term]
id: GO:0006511
@@ -66923,7 +69723,7 @@
synonym: "misfolded or incompletely synthesized protein degradation" EXACT []
synonym: "protein quality control (PQC)" EXACT []
synonym: "protein quality control by the ubiquitin-proteasome system" BROAD []
-is_a: GO:0051603 ! proteolysis involved in protein catabolic process
+is_a: GO:0030163 ! protein catabolic process
[Term]
id: GO:0006516
@@ -67013,14 +69813,16 @@
[Term]
id: GO:0006524
-name: alanine catabolic process
+name: obsolete alanine catabolic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid." [GOC:go_curators]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid." [GOC:go_curators]
+comment: The reason for obsoletion is that a more specific term has been created.
synonym: "alanine breakdown" EXACT []
synonym: "alanine catabolism" EXACT []
synonym: "alanine degradation" EXACT []
-is_a: GO:0006522 ! alanine metabolic process
-is_a: GO:1901606 ! alpha-amino acid catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31068" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0042853
[Term]
id: GO:0006525
@@ -67040,8 +69842,14 @@
synonym: "arginine biosynthesis" EXACT []
synonym: "arginine formation" EXACT []
synonym: "arginine synthesis" EXACT []
+xref: MetaCyc:ARGSYN-PWY
+xref: MetaCyc:ARGSYNBSUB-PWY
+xref: MetaCyc:PWY-7400
is_a: GO:0006525 ! arginine metabolic process
-is_a: GO:0009084 ! glutamine family amino acid biosynthetic process
+is_a: GO:0009084 ! L-glutamine family amino acid biosynthetic process
+property_value: skos:narrowMatch MetaCyc:ARGSYN-PWY
+property_value: skos:narrowMatch MetaCyc:ARGSYNBSUB-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-7400
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28686" xsd:anyURI
@@ -67054,7 +69862,6 @@
synonym: "arginine catabolism" EXACT []
synonym: "arginine degradation" EXACT []
is_a: GO:0006525 ! arginine metabolic process
-is_a: GO:0009064 ! glutamine family amino acid metabolic process
is_a: GO:0170035 ! L-amino acid catabolic process
is_a: GO:0170040 ! proteinogenic amino acid catabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
@@ -67106,16 +69913,18 @@
[Term]
id: GO:0006532
-name: aspartate biosynthetic process
+name: L-aspartate biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid." [GOC:go_curators, ISBN:0198506732]
+def: "The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid." [GOC:go_curators, ISBN:0198506732, MetaCyc:ASPARTATESYN-PWY]
synonym: "aspartate anabolism" EXACT []
synonym: "aspartate biosynthesis" EXACT []
synonym: "aspartate formation" EXACT []
synonym: "aspartate synthesis" EXACT []
+xref: MetaCyc:ASPARTATESYN-PWY
is_a: GO:0006531 ! aspartate metabolic process
is_a: GO:0009067 ! aspartate family amino acid biosynthetic process
is_a: GO:0043650 ! dicarboxylic acid biosynthetic process
+property_value: skos:exactMatch MetaCyc:ASPARTATESYN-PWY
[Term]
id: GO:0006533
@@ -67143,15 +69952,20 @@
[Term]
id: GO:0006535
-name: cysteine biosynthetic process from serine
+name: L-cysteine biosynthetic process from L-serine
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine." [GOC:go_curators]
+def: "The chemical reactions and pathways resulting in the formation of cysteine from L- serine." [MetaCyc:CYSTSYN-PWY]
synonym: "cysteine anabolism from serine" EXACT []
synonym: "cysteine formation from serine" EXACT []
synonym: "cysteine synthesis from serine" EXACT []
xref: MetaCyc:CYSTSYN-PWY
is_a: GO:0006563 ! L-serine metabolic process
-is_a: GO:0019344 ! cysteine biosynthetic process
+is_a: GO:0019344 ! L-cysteine biosynthetic process
+is_a: GO:0046439 ! L-cysteine metabolic process
+is_a: GO:0170034 ! L-amino acid biosynthetic process
+is_a: GO:0170038 ! proteinogenic amino acid biosynthetic process
+property_value: skos:exactMatch MetaCyc:CYSTSYN-PWY
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30758" xsd:anyURI
[Term]
id: GO:0006536
@@ -67162,8 +69976,8 @@
synonym: "glutamic acid metabolic process" EXACT []
synonym: "glutamic acid metabolism" EXACT []
xref: Wikipedia:Glutamic_acid
-is_a: GO:0009064 ! glutamine family amino acid metabolic process
is_a: GO:0043648 ! dicarboxylic acid metabolic process
+is_a: GO:1901605 ! alpha-amino acid metabolic process
[Term]
id: GO:0006537
@@ -67181,7 +69995,7 @@
synonym: "glutamic acid biosynthesis" EXACT []
synonym: "glutamic acid biosynthetic process" EXACT []
is_a: GO:0006536 ! glutamate metabolic process
-is_a: GO:0009084 ! glutamine family amino acid biosynthetic process
+is_a: GO:0009084 ! L-glutamine family amino acid biosynthetic process
is_a: GO:0043650 ! dicarboxylic acid biosynthetic process
[Term]
@@ -67248,7 +70062,7 @@
namespace: biological_process
def: "The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid." [GOC:ai]
synonym: "glutamine metabolism" EXACT []
-is_a: GO:0009064 ! glutamine family amino acid metabolic process
+is_a: GO:0019752 ! carboxylic acid metabolic process
[Term]
id: GO:0006542
@@ -67260,8 +70074,11 @@
synonym: "glutamine formation" EXACT []
synonym: "glutamine synthesis" EXACT []
xref: MetaCyc:GLNSYN-PWY
+xref: MetaCyc:PWY-6549
is_a: GO:0006541 ! glutamine metabolic process
-is_a: GO:0009084 ! glutamine family amino acid biosynthetic process
+is_a: GO:0009084 ! L-glutamine family amino acid biosynthetic process
+property_value: skos:narrowMatch MetaCyc:GLNSYN-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-6549
[Term]
id: GO:0006543
@@ -67290,7 +70107,7 @@
id: GO:0006545
name: glycine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid." [GOC:go_curators]
+def: "The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid." [GOC:go_curators, MetaCyc:GLYCINE-SYN2-PWY]
synonym: "glycine anabolism" EXACT []
synonym: "glycine biosynthesis" EXACT []
synonym: "glycine formation" EXACT []
@@ -67299,6 +70116,7 @@
is_a: GO:0006544 ! glycine metabolic process
is_a: GO:0009070 ! serine family amino acid biosynthetic process
is_a: GO:0170038 ! proteinogenic amino acid biosynthetic process
+property_value: skos:narrowMatch MetaCyc:GLYCINE-SYN2-PWY
[Term]
id: GO:0006546
@@ -67359,10 +70177,15 @@
synonym: "isoleucine breakdown" EXACT []
synonym: "isoleucine catabolism" EXACT []
synonym: "isoleucine degradation" EXACT []
+xref: MetaCyc:ILEUDEG-PWY
+xref: MetaCyc:PWY-5078
+xref: MetaCyx:PWY-8184
is_a: GO:0006549 ! isoleucine metabolic process
is_a: GO:0009083 ! branched-chain amino acid catabolic process
is_a: GO:0170035 ! L-amino acid catabolic process
is_a: GO:0170040 ! proteinogenic amino acid catabolic process
+property_value: skos:narrowMatch MetaCyc:ILEUDEG-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-5078
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30047" xsd:anyURI
[Term]
@@ -67385,10 +70208,20 @@
synonym: "L-leucine catabolism" EXACT []
synonym: "L-leucine degradation" EXACT []
synonym: "leucine catabolic process" BROAD []
+xref: MetaCyc:LEU-DEG2-PWY
+xref: MetaCyc:PWY-5075
+xref: MetaCyc:PWY-5076
+xref: MetaCyc:PWY-7767
+xref: MetaCyc:PWY-8185
is_a: GO:0006551 ! L-leucine metabolic process
is_a: GO:0009083 ! branched-chain amino acid catabolic process
is_a: GO:0170035 ! L-amino acid catabolic process
is_a: GO:0170040 ! proteinogenic amino acid catabolic process
+property_value: skos:narrowMatch MetaCyc:LEU-DEG2-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-5075
+property_value: skos:narrowMatch MetaCyc:PWY-5076
+property_value: skos:narrowMatch MetaCyc:PWY-7767
+property_value: skos:narrowMatch MetaCyc:PWY-8185
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30047" xsd:anyURI
[Term]
@@ -67402,15 +70235,17 @@
[Term]
id: GO:0006554
-name: lysine catabolic process
+name: obsolete lysine catabolic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid." [GOC:go_curators]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid." [GOC:go_curators]
+comment: The reason for obsoletion is that more specific terms were created.
synonym: "lysine breakdown" EXACT []
synonym: "lysine catabolism" EXACT []
synonym: "lysine degradation" EXACT []
xref: Reactome:R-HSA-71064 "Lysine catabolism"
-is_a: GO:0006553 ! lysine metabolic process
-is_a: GO:1901606 ! alpha-amino acid catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31068" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0019477
[Term]
id: GO:0006555
@@ -67485,11 +70320,12 @@
[Term]
id: GO:0006560
-name: proline metabolic process
+name: L-proline metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732]
synonym: "proline metabolism" EXACT []
-is_a: GO:0009064 ! glutamine family amino acid metabolic process
+is_a: GO:0170033 ! L-amino acid metabolic process
+is_a: GO:0170039 ! proteinogenic amino acid metabolic process
[Term]
id: GO:0006561
@@ -67515,7 +70351,7 @@
synonym: "proline catabolism" EXACT []
synonym: "proline degradation" EXACT []
xref: Reactome:R-HSA-70688 "Proline catabolism"
-is_a: GO:0006560 ! proline metabolic process
+is_a: GO:0006560 ! L-proline metabolic process
is_a: GO:0170035 ! L-amino acid catabolic process
is_a: GO:0170040 ! proteinogenic amino acid catabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
@@ -67533,7 +70369,7 @@
id: GO:0006564
name: L-serine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid." [GOC:ai, GOC:jsg]
+def: "The chemical reactions and pathways resulting in the formation of L-serine." [MetaCyc:SERSYN-PWY]
synonym: "L-serine anabolism" EXACT []
synonym: "L-serine biosynthesis" EXACT []
synonym: "L-serine formation" EXACT []
@@ -67544,12 +70380,13 @@
is_a: GO:0009070 ! serine family amino acid biosynthetic process
is_a: GO:0170034 ! L-amino acid biosynthetic process
is_a: GO:0170038 ! proteinogenic amino acid biosynthetic process
+property_value: skos:exactMatch MetaCyc:SERSYN-PWY
[Term]
id: GO:0006565
name: L-serine catabolic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid." [GOC:ai, GOC:jsg]
+def: "The chemical reactions and pathways resulting in the breakdown of L-serine to pyruvate and free ammonium." [MetaCyc:SERDEG-PWY]
synonym: "L-serine breakdown" EXACT []
synonym: "L-serine catabolism" EXACT []
synonym: "L-serine degradation" EXACT []
@@ -67557,10 +70394,12 @@
is_a: GO:0006563 ! L-serine metabolic process
is_a: GO:0170035 ! L-amino acid catabolic process
is_a: GO:0170040 ! proteinogenic amino acid catabolic process
+property_value: skos:exactMatch MetaCyc:SERDEG-PWY
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30758" xsd:anyURI
[Term]
id: GO:0006566
-name: threonine metabolic process
+name: L-threonine metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732]
synonym: "methionine and threonine metabolic process" BROAD []
@@ -67578,7 +70417,7 @@
synonym: "threonine catabolism" EXACT []
synonym: "threonine degradation" EXACT []
xref: UM-BBD_pathwayID:met
-is_a: GO:0006566 ! threonine metabolic process
+is_a: GO:0006566 ! L-threonine metabolic process
is_a: GO:0170035 ! L-amino acid catabolic process
is_a: GO:0170040 ! proteinogenic amino acid catabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
@@ -67636,7 +70475,7 @@
synonym: "tyrosine formation" EXACT []
synonym: "tyrosine synthesis" EXACT []
is_a: GO:0006570 ! tyrosine metabolic process
-is_a: GO:0009095 ! aromatic amino acid family biosynthetic process, prephenate pathway
+is_a: GO:0009073 ! aromatic amino acid family biosynthetic process
is_a: GO:0170034 ! L-amino acid biosynthetic process
is_a: GO:0170038 ! proteinogenic amino acid biosynthetic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20583" xsd:anyURI
@@ -67669,15 +70508,23 @@
id: GO:0006574
name: L-valine catabolic process
namespace: biological_process
+alt_id: GO:1990292
def: "The chemical reactions and pathways resulting in the breakdown of L-valine, 2-amino-3-methylbutanoic acid." [GOC:ai]
synonym: "valine breakdown" EXACT []
synonym: "valine catabolism" EXACT []
synonym: "valine degradation" EXACT []
+xref: MetaCyc:PWY-5057
+xref: MetaCyc:PWY-8183
+xref: MetaCyc:VALDEG-PWY
is_a: GO:0006573 ! valine metabolic process
is_a: GO:0009083 ! branched-chain amino acid catabolic process
is_a: GO:0170035 ! L-amino acid catabolic process
is_a: GO:0170040 ! proteinogenic amino acid catabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-5057
+property_value: skos:narrowMatch MetaCyc:PWY-8183
+property_value: skos:narrowMatch MetaCyc:VALDEG-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30047" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31221" xsd:anyURI
[Term]
id: GO:0006575
@@ -67815,15 +70662,17 @@
[Term]
id: GO:0006587
-name: serotonin biosynthetic process from tryptophan
+name: serotonin biosynthetic process from L-tryptophan
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation from tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732]
+def: "The chemical reactions and pathways resulting in the formation from L-tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732, PMID:30901029, PMID:35495641]
synonym: "serotonin anabolism from tryptophan" EXACT []
synonym: "serotonin formation from tryptophan" EXACT []
synonym: "serotonin synthesis from tryptophan" EXACT []
-is_a: GO:0009072 ! aromatic amino acid metabolic process
+is_a: GO:0006568 ! L-tryptophan metabolic process
is_a: GO:0042427 ! serotonin biosynthetic process
-is_a: GO:1901605 ! alpha-amino acid metabolic process
+property_value: skos:relatedMatch MetaCyc:PWY-6030
+property_value: skos:relatedMatch MetaCyc:PWY-8475
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31021" xsd:anyURI
[Term]
id: GO:0006588
@@ -67876,9 +70725,11 @@
synonym: "ornithine biosynthesis" EXACT []
synonym: "ornithine formation" EXACT []
synonym: "ornithine synthesis" EXACT []
+xref: MetaCyc:ARGININE-SYN4-PWY
is_a: GO:0006591 ! ornithine metabolic process
is_a: GO:0170043 ! non-proteinogenic amino acid biosynthetic process
is_a: GO:1901607 ! alpha-amino acid biosynthetic process
+property_value: skos:narrowMatch MetaCyc:ARGININE-SYN4-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -67914,20 +70765,25 @@
synonym: "polyamine biosynthesis" EXACT []
synonym: "polyamine formation" EXACT []
synonym: "polyamine synthesis" EXACT []
+xref: MetaCyc:POLYAMINSYN3-PWY
+xref: MetaCyc:POLYAMSYN-PWY
xref: Reactome:R-HSA-351200 "Interconversion of polyamines"
is_a: GO:0006595 ! polyamine metabolic process
is_a: GO:0042401 ! biogenic amine biosynthetic process
+property_value: skos:narrowMatch MetaCyc:POLYAMINSYN3-PWY
+property_value: skos:narrowMatch MetaCyc:POLYAMSYN-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
id: GO:0006597
name: spermine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging." [GOC:curators]
+def: "The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging." [GOC:curators, MetaCyc:ARGSPECAT-PWY]
synonym: "spermine anabolism" EXACT []
synonym: "spermine biosynthesis" EXACT []
synonym: "spermine formation" EXACT []
synonym: "spermine synthesis" EXACT []
+xref: MetaCyc:ARGSPECAT-PWY
is_a: GO:0006596 ! polyamine biosynthetic process
is_a: GO:0008215 ! spermine metabolic process
@@ -68256,30 +71112,34 @@
[Term]
id: GO:0006626
-name: protein targeting to mitochondrion
+name: obsolete protein targeting to mitochondrion
namespace: biological_process
alt_id: GO:0043681
-def: "The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein." [GOC:mcc, ISBN:0716731363]
+def: "OBSOLETE. The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein." [GOC:mcc, ISBN:0716731363]
+comment: The reason for obsoletion is that this term was added in error.
synonym: "mitochondrial protein import" RELATED []
synonym: "mitochondrial translocation" RELATED []
synonym: "protein import into mitochondrion" EXACT []
synonym: "protein targeting to mitochondria" EXACT []
synonym: "protein-mitochondrial targeting" EXACT []
xref: Reactome:R-HSA-1268020 "Mitochondrial protein import"
-is_a: GO:0006605 ! protein targeting
-is_a: GO:0072655 ! establishment of protein localization to mitochondrion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30349" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0070585
+created_by: dragon-ai-agent
[Term]
id: GO:0006627
-name: protein processing involved in protein targeting to mitochondrion
+name: obsolete protein processing involved in protein targeting to mitochondrion
namespace: biological_process
-def: "The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments." [GOC:mcc, PMID:12191769]
+def: "OBSOLETE. The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments." [GOC:mcc, PMID:12191769]
+comment: The reason for obsoletion is that this term was added in error.
synonym: "mitochondrial processing" BROAD []
synonym: "mitochondrial protein processing during import" RELATED [GOC:dph, GOC:tb]
-is_a: GO:0034982 ! mitochondrial protein processing
-intersection_of: GO:0016485 ! protein processing
-intersection_of: part_of GO:0006626 ! protein targeting to mitochondrion
-relationship: part_of GO:0006626 ! protein targeting to mitochondrion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30349" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0070585
+created_by: dragon-ai-agent
[Term]
id: GO:0006628
@@ -68289,7 +71149,7 @@
comment: This term was made obsolete because its definition was equivalent to that of the biological process term 'mitochondrial matrix protein import ; GO:0030150' while the mitochondrial translocation has a broader meaning; this led to mis-annotation.
synonym: "mitochondrial translocation" EXACT []
is_obsolete: true
-consider: GO:0006626
+consider: GO:0070585
[Term]
id: GO:0006629
@@ -68350,10 +71210,16 @@
synonym: "fatty acid biosynthesis" EXACT []
synonym: "fatty acid formation" EXACT []
synonym: "fatty acid synthesis" EXACT []
+xref: MetaCyc:FASYN-INITIAL-PWY
+xref: MetaCyc:PWY-4381
+xref: MetaCyc:PWY-5156
xref: Wikipedia:Fatty_acid_synthesis
is_a: GO:0006631 ! fatty acid metabolic process
is_a: GO:0008610 ! lipid biosynthetic process
is_a: GO:0072330 ! monocarboxylic acid biosynthetic process
+property_value: skos:narrowMatch MetaCyc:FASYN-INITIAL-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-4381
+property_value: skos:narrowMatch MetaCyc:PWY-5156
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -68392,8 +71258,12 @@
synonym: "unsaturated fatty acid biosynthesis" EXACT []
synonym: "unsaturated fatty acid formation" EXACT []
synonym: "unsaturated fatty acid synthesis" EXACT []
+xref: MetaCyc:PWY-762
+xref: MetaCyc:PWY-782
is_a: GO:0006633 ! fatty acid biosynthetic process
is_a: GO:0033559 ! unsaturated fatty acid metabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-762
+property_value: skos:narrowMatch MetaCyc:PWY-782
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -68404,7 +71274,6 @@
synonym: "acyl-CoA metabolism" EXACT []
is_a: GO:0006753 ! nucleoside phosphate metabolic process
is_a: GO:0006790 ! sulfur compound metabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0072521 ! purine-containing compound metabolic process
[Term]
@@ -68462,13 +71331,15 @@
[Term]
id: GO:0006643
-name: membrane lipid metabolic process
+name: obsolete membrane lipid metabolic process
namespace: biological_process
-def: "The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai]
+def: "OBSOLETE. The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai]
+comment: The reason for obsoletion is that this term groups lipids by their localization rather than by their metabolic function, which is problematic since most lipids can function in multiple locations.
synonym: "membrane lipid metabolism" EXACT []
-is_a: GO:0006629 ! lipid metabolic process
-relationship: occurs_in GO:0016020 ! membrane
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26698" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0006629
[Term]
id: GO:0006644
@@ -68700,7 +71571,6 @@
namespace: biological_process
def: "The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent." [ISBN:0198547684]
synonym: "glycolipid metabolism" EXACT []
-is_a: GO:0006643 ! membrane lipid metabolic process
is_a: GO:1903509 ! liposaccharide metabolic process
[Term]
@@ -68710,7 +71580,7 @@
def: "The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:mah, ISBN:0198506732]
synonym: "sphingolipid metabolism" EXACT []
xref: Reactome:R-HSA-428157 "Sphingolipid metabolism"
-is_a: GO:0006643 ! membrane lipid metabolic process
+is_a: GO:0006629 ! lipid metabolic process
[Term]
id: GO:0006666
@@ -68789,7 +71659,6 @@
def: "The chemical reactions and pathways involving ceramides, any N-acylated sphingoid." [ISBN:0198547684]
synonym: "ceramide metabolism" EXACT []
is_a: GO:0006665 ! sphingolipid metabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0006673
@@ -68917,7 +71786,6 @@
synonym: "sphingomyelin metabolism" EXACT []
is_a: GO:0006644 ! phospholipid metabolic process
is_a: GO:0006665 ! sphingolipid metabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0006685
@@ -68943,7 +71811,6 @@
is_a: GO:0006684 ! sphingomyelin metabolic process
is_a: GO:0008654 ! phospholipid biosynthetic process
is_a: GO:0030148 ! sphingolipid biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
[Term]
id: GO:0006687
@@ -69731,7 +72598,6 @@
synonym: "oxidized glutathione reduction" NARROW []
is_a: GO:0006575 ! modified amino acid metabolic process
is_a: GO:0006790 ! sulfur compound metabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0006750
@@ -69747,7 +72613,6 @@
is_a: GO:0006749 ! glutathione metabolic process
is_a: GO:0019184 ! nonribosomal peptide biosynthetic process
is_a: GO:0042398 ! modified amino acid biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0044272 ! sulfur compound biosynthetic process
[Term]
@@ -69901,7 +72766,6 @@
xref: Wikipedia:Biotin
is_a: GO:0006790 ! sulfur compound metabolic process
is_a: GO:0032787 ! monocarboxylic acid metabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0006769
@@ -69915,7 +72779,6 @@
synonym: "vitamin B3 metabolism" BROAD []
xref: MetaCyc:PWY-5083
is_a: GO:0009820 ! alkaloid metabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0072524 ! pyridine-containing compound metabolic process
[Term]
@@ -70812,6 +73675,7 @@
namespace: biological_process
def: "The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages." [ISBN:0198506732]
is_a: GO:0015833 ! peptide transport
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0006858
@@ -71162,10 +74026,11 @@
id: GO:0006893
name: Golgi to plasma membrane transport
namespace: biological_process
-def: "The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis." [ISBN:0716731363]
+def: "The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. Golgi to plasma membrane transport precedes exocytosis." [ISBN:0716731363]
synonym: "Golgi to plasma membrane vesicle-mediated transport" EXACT []
is_a: GO:0006892 ! post-Golgi vesicle-mediated transport
is_a: GO:0098876 ! vesicle-mediated transport to the plasma membrane
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31197" xsd:anyURI
[Term]
id: GO:0006894
@@ -71176,8 +74041,8 @@
synonym: "Golgi to secretory vesicle transport" EXACT []
synonym: "Golgi to secretory vesicle transport, vesicle-mediated" EXACT []
is_obsolete: true
+consider: GO:0006893
consider: GO:0055107
-consider: GO:0055108
[Term]
id: GO:0006895
@@ -77445,26 +80310,30 @@
[Term]
id: GO:0007545
-name: processes downstream of sex determination signal
+name: obsolete processes downstream of sex determination signal
namespace: biological_process
-def: "The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways." [GOC:mah]
-is_a: GO:0007530 ! sex determination
-relationship: part_of GO:0007275 ! multicellular organism development
+def: "OBSOLETE. The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways." [GOC:mah]
+comment: The reason for obsoletion is that the meaning of the term is ambiguous.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30953" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0007546
-name: somatic processes downstream of sex determination signal
+name: obsolete somatic processes downstream of sex determination signal
namespace: biological_process
-def: "The events determining the somatic sexual phenotype after the initial transmission of that phenotype to soma-specific information pathways." [GOC:ems]
-is_a: GO:0007545 ! processes downstream of sex determination signal
+def: "OBSOLETE. The events determining the somatic sexual phenotype after the initial transmission of that phenotype to soma-specific information pathways." [GOC:ems]
+comment: The reason for obsoletion is that the meaning of the term is ambiguous.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30953" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0007547
-name: germ-line processes downstream of sex determination signal
+name: obsolete germ-line processes downstream of sex determination signal
namespace: biological_process
-def: "The events determining the germ-line sexual phenotype after the initial transmission of that phenotype to germ-line-specific information pathways." [GOC:ems]
-is_a: GO:0007545 ! processes downstream of sex determination signal
-relationship: part_of GO:0018992 ! germ-line sex determination
+def: "OBSOLETE. The events determining the germ-line sexual phenotype after the initial transmission of that phenotype to germ-line-specific information pathways." [GOC:ems]
+comment: The reason for obsoletion is that the meaning of the term is ambiguous.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30953" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0007548
@@ -78643,7 +81512,7 @@
def: "Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group." [GOC:ai]
synonym: "monocarboxylate carrier" NARROW []
synonym: "prostaglandin/thromboxane transporter activity" NARROW []
-xref: Reactome:R-HSA-429749 "SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol"
+xref: Reactome:R-HSA-429749 "SLC5A8 transports monocarboxylates from extracellular region to cytosol"
xref: Reactome:R-HSA-433698 "SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol"
xref: Reactome:R-HSA-5624211 "Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol"
xref: Reactome:R-HSA-9645220 "SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol"
@@ -78811,7 +81680,6 @@
def: "A molecular function regulator that increases a catalytic activity." [GOC:pdt]
comment: This term should only be used in cases when the regulator directly interacts with the enzyme, but does not result in a covalent modification.
synonym: "metalloenzyme activator activity" NARROW []
-xref: Reactome:R-HSA-9948070 "POMGNT1 catalyzes FKRP:FKTN:RXYLT1 formation"
is_a: GO:0030234 ! enzyme regulator activity
is_a: GO:0140677 ! molecular function activator activity
relationship: positively_regulates GO:0003824 ! catalytic activity
@@ -79034,7 +81902,6 @@
name: ornithine decarboxylase inhibitor activity
namespace: molecular_function
def: "Binds to and stops, prevents or reduces the activity of ornithine decarboxylase." [GOC:jl]
-xref: Reactome:R-HSA-350567 "Antizyme OAZ binds to Ornithine decarboxylase"
is_a: GO:0004857 ! enzyme inhibitor activity
is_a: GO:0042979 ! ornithine decarboxylase regulator activity
relationship: negatively_regulates GO:0004586 ! ornithine decarboxylase activity
@@ -79108,7 +81975,6 @@
xref: Reactome:R-HSA-2473152 "Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2"
xref: Reactome:R-HSA-6790987 "NAT10 acetylates cytidine-1337 and cytidine-1842 of 18S rRNA yielding 4-acetylcytidine-1377 and 4-acetylcytidine-1842"
xref: Reactome:R-HSA-9636560 "Eis acetylates DUSP16"
-xref: Reactome:R-HSA-9913373 "AAC(6)-Ib acetylates ciprofloxacin"
is_a: GO:0016407 ! acetyltransferase activity
is_a: GO:0016410 ! N-acyltransferase activity
@@ -79124,6 +81990,8 @@
xref: EC:3.1.4.-
xref: Reactome:R-HSA-5693578 "TDP1 and TDP2 process unligatable DSB ends"
is_a: GO:0042578 ! phosphoric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008083
@@ -79335,28 +82203,12 @@
synonym: "aldehyde reductase (NADPH) activity" EXACT []
synonym: "NADP-aldehyde reductase activity" EXACT []
xref: EC:1.1.1.2
-xref: Reactome:R-HSA-192033 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one"
-xref: Reactome:R-HSA-192036 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol"
-xref: Reactome:R-HSA-192067 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one"
-xref: Reactome:R-HSA-192160 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol"
-xref: Reactome:R-HSA-193746 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one"
-xref: Reactome:R-HSA-193755 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one"
-xref: Reactome:R-HSA-193758 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol"
-xref: Reactome:R-HSA-193781 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol"
-xref: Reactome:R-HSA-193800 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol"
-xref: Reactome:R-HSA-193821 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one"
-xref: Reactome:R-HSA-193824 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one"
-xref: Reactome:R-HSA-193841 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol"
-xref: Reactome:R-HSA-198845 "CYB5A:heme reduces Asc.- to AscH-"
-xref: Reactome:R-HSA-2855252 "AKRs reduce RBP2:atRAL to RBP2:atROL"
-xref: Reactome:R-HSA-5423637 "AKR dimers reduce AFBDHO to AFBDOH"
-xref: Reactome:R-HSA-5692232 "AKR1A1 oxidises BaPtDHD to BaP-7,8-dione"
-xref: Reactome:R-HSA-9027531 "Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA"
-xref: Reactome:R-HSA-9027562 "Dehydrogenase dehydrogenates 17-HDHA to 17-oxo-DHA"
-xref: Reactome:R-HSA-9027598 "Dehydrogenase dehydrogenates 13(R)-HDPAn-3 to 13-oxo-DPAn-3"
-xref: Reactome:R-HSA-9027600 "Dehydrogenase dehydrogenates 17-HDPAn-3 to 17-oxo-DPAn-3"
-xref: Reactome:R-HSA-9937340 "DHRSX reduces dolichal to dolichol"
+xref: MetaCyc:ALCOHOL-DEHYDROGENASE-NADPORNOP+-RXN
+xref: RHEA:15937
is_a: GO:0018455 ! alcohol dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.1.1.2
+property_value: skos:narrowMatch MetaCyc:ALCOHOL-DEHYDROGENASE-NADPORNOP+-RXN
+property_value: skos:narrowMatch RHEA:15937
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28532" xsd:anyURI
@@ -79396,6 +82248,9 @@
xref: Reactome:R-HSA-9603983 "FUT2 transfers Fuc to LeX to form LeY"
xref: RHEA:50664
is_a: GO:0031127 ! alpha-(1,2)-fucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.69
+property_value: skos:exactMatch RHEA:50664
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008108
@@ -79420,6 +82275,9 @@
xref: Reactome:R-HSA-70361 "GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal"
xref: RHEA:13989
is_a: GO:0070569 ! uridylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.12
+property_value: skos:exactMatch RHEA:13989
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008109
@@ -79433,9 +82291,14 @@
synonym: "UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide beta-1,6-N-acetyl-D-glucosaminyltransferase activity" RELATED [EC:2.4.1.150]
synonym: "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase" BROAD [EC:2.4.1.150]
xref: EC:2.4.1.150
+xref: MetaCyc:2.4.1.150-RXN
xref: RHEA:17413
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.150
+property_value: skos:exactMatch RHEA:17413
+property_value: skos:narrowMatch MetaCyc:2.4.1.150-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30174" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008110
@@ -79450,6 +82313,9 @@
xref: MetaCyc:HISTTRANSAM-RXN
xref: RHEA:16565
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.38
+property_value: skos:exactMatch RHEA:16565
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008111
@@ -79466,6 +82332,9 @@
xref: Reactome:R-HSA-389897 "Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA"
xref: RHEA:12657
is_a: GO:0016854 ! racemase and epimerase activity
+property_value: skos:exactMatch EC:5.1.99.4
+property_value: skos:exactMatch RHEA:12657
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008112
@@ -79481,6 +82350,9 @@
xref: RHEA:23884
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.1
+property_value: skos:exactMatch RHEA:23884
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008113
@@ -79498,6 +82370,8 @@
xref: RHEA:14217
is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:broadMatch EC:1.8.4.11
+property_value: skos:exactMatch RHEA:14217
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30723" xsd:anyURI
[Term]
@@ -79515,6 +82389,8 @@
xref: EC:1.1.1.43
xref: MetaCyc:1.1.1.43-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.43
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008115
@@ -79527,6 +82403,9 @@
xref: MetaCyc:SARCOX-RXN
xref: RHEA:13313
is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.5.3.1
+property_value: skos:exactMatch RHEA:13313
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008116
@@ -79548,6 +82427,9 @@
xref: Reactome:R-HSA-76496 "PTGIS, CYP8A1 isomerise PGH2 to PGI2"
xref: RHEA:23580
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:exactMatch EC:5.3.99.4
+property_value: skos:exactMatch RHEA:23580
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008117
@@ -79567,6 +82449,9 @@
xref: Reactome:R-HSA-428681 "PXLP-SGPL1 cleaves sphingoid-1-phosphates"
xref: RHEA:18593
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.27
+property_value: skos:exactMatch RHEA:18593
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008118
@@ -79582,7 +82467,10 @@
xref: MetaCyc:2.4.99.6-RXN
xref: RHEA:52316
is_a: GO:0008373 ! sialyltransferase activity
+property_value: skos:exactMatch EC:2.4.3.6
+property_value: skos:exactMatch RHEA:52316
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28444" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008119
@@ -79602,6 +82490,8 @@
xref: Reactome:R-HSA-9748983 "TPMT transfers methyl group to 6MP, forming 6MeMP"
is_a: GO:0008172 ! S-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.67
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008120
@@ -79621,6 +82511,8 @@
xref: Reactome:R-HSA-1638104 "UGCG transfers glucose to ceramide"
xref: RHEA:12088
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.80
+property_value: skos:exactMatch RHEA:12088
[Term]
id: GO:0008121
@@ -79658,6 +82550,8 @@
is_a: GO:0015453 ! oxidoreduction-driven active transmembrane transporter activity
is_a: GO:0022853 ! active monoatomic ion transmembrane transporter activity
relationship: has_part GO:0016679 ! oxidoreductase activity, acting on diphenols and related substances as donors
+property_value: skos:exactMatch EC:7.1.1.8
+property_value: skos:exactMatch RHEA:11484
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20616" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21275" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
@@ -79679,6 +82573,8 @@
xref: RHEA:21812
is_a: GO:0008387 ! steroid 7-alpha-hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.23
+property_value: skos:exactMatch RHEA:21812
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29041" xsd:anyURI
[Term]
@@ -79701,6 +82597,9 @@
xref: Reactome:R-HSA-71146 "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O"
xref: RHEA:11920
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.96
+property_value: skos:exactMatch RHEA:11920
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008125
@@ -79731,6 +82630,9 @@
xref: RHEA:12957
xref: UM-BBD_reactionID:r0170
is_a: GO:0034338 ! short-chain carboxylesterase activity
+property_value: skos:exactMatch EC:3.1.1.6
+property_value: skos:exactMatch RHEA:12957
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008127
@@ -79747,6 +82649,9 @@
xref: RHEA:15381
xref: UM-BBD_reactionID:r0891
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.24
+property_value: skos:exactMatch RHEA:15381
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008129
@@ -79787,6 +82692,10 @@
synonym: "primary-amine:oxygen oxidoreductase (deaminating) activity" EXACT systematic_synonym [EC:1.4.3.21]
xref: EC:1.4.3.21
xref: KEGG_REACTION:R01853
+xref: KEGG_REACTION:R02173
+xref: KEGG_REACTION:R02613
+xref: MetaCyc:RXN-10817
+xref: MetaCyc:RXN-1401
xref: MetaCyc:RXN-9597
xref: Reactome:R-HSA-141186 "MAOA:FAD oxidatively deaminates of 5HT"
xref: Reactome:R-HSA-141200 "MAOB:FAD oxidatively deaminates of PEA"
@@ -79799,6 +82708,14 @@
xref: Reactome:R-HSA-5696183 "AOC3 deaminates BZAM"
xref: RHEA:16153
is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.4.3.21
+property_value: skos:exactMatch KEGG_REACTION:R01853
+property_value: skos:exactMatch MetaCyc:RXN-9597
+property_value: skos:exactMatch RHEA:16153
+property_value: skos:narrowMatch KEGG_REACTION:R02173
+property_value: skos:narrowMatch KEGG_REACTION:R02613
+property_value: skos:narrowMatch MetaCyc:RXN-10817
+property_value: skos:narrowMatch MetaCyc:RXN-1401
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -79892,10 +82809,13 @@
is_a: GO:0022853 ! active monoatomic ion transmembrane transporter activity
relationship: has_part GO:0003954 ! NADH dehydrogenase activity
relationship: has_part GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:7.1.1.2
+property_value: skos:exactMatch RHEA:29091
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20616" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21275" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25784" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27641" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30272" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30619" xsd:anyURI
@@ -79992,6 +82912,7 @@
xref: Reactome:R-HSA-2022061 "Dermatan sulfate can be further sulfated on position 2 of iduronate"
xref: Reactome:R-HSA-9753277 "SULT dimers sulfate APAP to APAP-SO3"
is_a: GO:0016782 ! transferase activity, transferring sulphur-containing groups
+property_value: skos:exactMatch EC:2.8.2.-
[Term]
id: GO:0008147
@@ -80090,10 +83011,16 @@
synonym: "para-aminobenzoic acid synthesis" EXACT []
synonym: "vitamin Bx biosynthesis" EXACT []
synonym: "vitamin Bx biosynthetic process" EXACT []
+xref: MetaCyc:PWY-6543
+xref: MetaCyc:PWY-8276
+xref: MetaCyc:PWY-8281
is_a: GO:0008652 ! amino acid biosynthetic process
is_a: GO:0009073 ! aromatic amino acid family biosynthetic process
is_a: GO:0046482 ! para-aminobenzoic acid metabolic process
is_a: GO:0072330 ! monocarboxylic acid biosynthetic process
+property_value: skos:narrowMatch MetaCyc:PWY-6543
+property_value: skos:narrowMatch MetaCyc:PWY-8276
+property_value: skos:narrowMatch MetaCyc:PWY-8281
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
[Term]
@@ -80246,11 +83173,12 @@
xref: Reactome:R-HSA-212269 "DNMT1,3A,3B:PRC2 methylates cytosine and histone H3"
xref: Reactome:R-HSA-379387 "COMT transfers Met to DA to form 3MT"
xref: Reactome:R-HSA-379464 "COMT transfers Met to DOPAC to form HVA"
-xref: Reactome:R-HSA-5333608 "GSSebGalNac is reduced and methylated to MeSebGalNac"
xref: Reactome:R-HSA-6800149 "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII"
xref: Reactome:R-HSA-71286 "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine"
xref: Reactome:R-HSA-9710490 "The GSDME gene promoter is hypermethylated"
is_a: GO:0016741 ! transferase activity, transferring one-carbon groups
+property_value: skos:exactMatch EC:2.1.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008169
@@ -80340,7 +83268,10 @@
xref: RHEA:42708
is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity
relationship: part_of GO:0106004 ! tRNA (guanine-N7)-methylation
+property_value: skos:exactMatch EC:2.1.1.33
+property_value: skos:exactMatch RHEA:42708
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26110" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008177
@@ -80348,6 +83279,7 @@
namespace: molecular_function
alt_id: GO:0019737
def: "Catalysis of the reaction: a quinone + succinate = a quinol + fumarate." [RHEA:40523]
+comment: This term represents the overall reaction of the entire SDH complex.
synonym: "fumarate reductase (menaquinone)" NARROW []
synonym: "succinate dehydrogenase (menaquinone)" NARROW []
synonym: "succinate dehydrogenase (ubiquinone) activity" NARROW []
@@ -80360,8 +83292,12 @@
xref: RHEA:40523
is_a: GO:0000104 ! succinate dehydrogenase activity
is_a: GO:0016635 ! oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor
+property_value: skos:exactMatch EC:1.3.5.1
+property_value: skos:exactMatch RHEA:40523
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26087" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27915" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30805" xsd:anyURI
[Term]
id: GO:0008179
@@ -80403,6 +83339,8 @@
xref: Reactome:R-HSA-71515 "glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]"
xref: Reactome:R-HSA-71590 "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL]"
is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity
+property_value: skos:broadMatch EC:2.4.1.1
+property_value: skos:exactMatch MetaCyc:GLYCOPHOSPHORYL-RXN
[Term]
id: GO:0008186
@@ -80482,6 +83420,9 @@
is_a: GO:0008192 ! RNA guanylyltransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
relationship: part_of GO:0099116 ! tRNA 5'-end processing
+property_value: skos:exactMatch EC:2.7.7.79
+property_value: skos:exactMatch RHEA:54564
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008194
@@ -80515,8 +83456,11 @@
xref: Reactome:R-HSA-75899 "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate"
xref: RHEA:27429
is_a: GO:0042577 ! lipid phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.4
+property_value: skos:exactMatch RHEA:27429
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24252" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25209" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008196
@@ -80541,7 +83485,6 @@
name: ferrous iron binding
namespace: molecular_function
def: "Binding to a ferrous iron ion, Fe(II)." [GOC:ai]
-xref: Reactome:R-HSA-1362416 "Frataxin binds iron"
is_a: GO:0005506 ! iron ion binding
[Term]
@@ -80883,9 +83826,10 @@
xref: Reactome:R-HSA-5684864 "NAPSA, CTSH, PGA3-5 cleave pro-SFTPB"
xref: Reactome:R-HSA-5685902 "NAPSA, CTSH, PGA3-5 cleave pro-SFTPC"
xref: Reactome:R-HSA-6803060 "DCD(63-110) is processed to DCD(63-109)"
-xref: Reactome:R-HSA-9935547 "Lysosomal degradation of ubiqutinated CDH1"
is_a: GO:0016787 ! hydrolase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:3.4.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008234
@@ -80895,7 +83839,7 @@
def: "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE]
synonym: "cysteine protease activity" NARROW []
synonym: "thiol protease activity" NARROW []
-xref: Reactome:R-HSA-2022381 "Cathepsin Z (Cathepsin X) hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8))"
+xref: Reactome:R-HSA-2022381 "Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)"
xref: Reactome:R-HSA-2467775 "Autocleavage of ESPL1 (Separase)"
xref: Reactome:R-HSA-2467809 "ESPL1 (Separase) cleaves centromeric cohesin"
xref: Reactome:R-HSA-5660752 "USP9X deubiquitinates Ub-SNCA"
@@ -80917,7 +83861,7 @@
def: "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE]
synonym: "serine protease activity" NARROW []
xref: Reactome:R-HSA-1461993 "pro-HD5 is cleaved by trypsin"
-xref: Reactome:R-HSA-2022383 "Chymase hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8))"
+xref: Reactome:R-HSA-2022383 "Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)"
xref: Reactome:R-HSA-3132753 "Pancreatic proteases degrade TCN1:RCbl"
xref: Reactome:R-HSA-6801766 "Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175)"
xref: Reactome:R-HSA-9839072 "HTRA2 degrades APP (Amyloid-beta precursor protein)"
@@ -80935,10 +83879,10 @@
xref: Reactome:R-HSA-157629 "NOTCH2-ligand complex is cleaved to produce NEXT2"
xref: Reactome:R-HSA-157632 "Complex of NOTCH1 with its ligand is cleaved to produce NEXT1"
xref: Reactome:R-HSA-193679 "alpha-secretase cleaves the p75NTR extracellular domain"
-xref: Reactome:R-HSA-2022368 "MME:Zn2+ (Neprilysin) hydrolyses AGT(25-33) (Angiotensin-(1-9)) to AGT(25-31) (Angiotensin-(1-7)"
-xref: Reactome:R-HSA-2022393 "ANPEP:Zn2+ hydrolyzes AGT(26-32) (Angiotensin-(2-8)) to AGT(27-32) (Angiotensin-(3-8))"
-xref: Reactome:R-HSA-2022396 "MME:Zn2+ (Neprilysin) hydrolyses AGT(25-34) (Angiotensin-(1-10)) to AGT(25-31) (Angiotensin-(1-7))"
-xref: Reactome:R-HSA-2022399 "ENPEP:Zn2+ hydrolyzes AGT(25-32) (Angiotensin-(1-8)) to AGT(26-32) (Angiotensin-(2-8))"
+xref: Reactome:R-HSA-2022368 "MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42)"
+xref: Reactome:R-HSA-2022393 "ANPEP:Zn2+ hydrolyzes Angiotensin-(2-8) to Angiotensin-(3-8)"
+xref: Reactome:R-HSA-2022396 "MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43)"
+xref: Reactome:R-HSA-2022399 "ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8)"
xref: Reactome:R-HSA-2220944 "ADAM10/17 cleaves ligand-bound NOTCH1 PEST domain mutants to produce NEXT1 PEST domain mutants"
xref: Reactome:R-HSA-2220976 "NOTCH1 HD+PEST domain mutants are cleaved by ADAM10/17 irrespective of ligand binding"
xref: Reactome:R-HSA-2666278 "NOTCH1 t(7;9)(NOTCH1:M1580_K2555) is cleaved to produce NEXT1"
@@ -80970,7 +83914,21 @@
name: dipeptidyl-peptidase activity
namespace: molecular_function
def: "Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain." [GOC:mb, https://www.ebi.ac.uk/merops/about/glossary.shtml#DIPEPTIDYL-PEPTIDASE]
+xref: EC:3.4.14.1
+xref: EC:3.4.14.11
+xref: EC:3.4.14.2
+xref: EC:3.4.14.4
+xref: EC:3.4.14.5
+xref: MetaCyc:3.4.14.11-RXN
+xref: MetaCyc:3.4.14.4-RXN
is_a: GO:0008238 ! exopeptidase activity
+property_value: skos:narrowMatch EC:3.4.14.1
+property_value: skos:narrowMatch EC:3.4.14.11
+property_value: skos:narrowMatch EC:3.4.14.2
+property_value: skos:narrowMatch EC:3.4.14.4
+property_value: skos:narrowMatch EC:3.4.14.5
+property_value: skos:narrowMatch MetaCyc:3.4.14.11-RXN
+property_value: skos:narrowMatch MetaCyc:3.4.14.4-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19681" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
@@ -80982,6 +83940,10 @@
xref: EC:3.4.14.10
xref: MetaCyc:3.4.14.10-RXN
is_a: GO:0070008 ! serine-type exopeptidase activity
+property_value: skos:broadMatch EC:3.4.14.9
+property_value: skos:broadMatch MetaCyc:3.4.14.9-RXN
+property_value: skos:exactMatch EC:3.4.14.10
+property_value: skos:exactMatch MetaCyc:3.4.14.10-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19681" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
@@ -80991,8 +83953,20 @@
namespace: molecular_function
def: "Catalysis of the release of C-terminal dipeptides from a polypeptide chain." [EC:3.4.15.-, GOC:mb]
xref: EC:3.4.15.-
+xref: EC:3.4.15.1
+xref: EC:3.4.15.5
+xref: EC:3.4.15.6
+xref: RHEA:12845
+xref: RHEA:63560
is_a: GO:0008238 ! exopeptidase activity
+property_value: skos:exactMatch EC:3.4.15.-
+property_value: skos:narrowMatch EC:3.4.15.1
+property_value: skos:narrowMatch EC:3.4.15.5
+property_value: skos:narrowMatch EC:3.4.15.6
+property_value: skos:narrowMatch RHEA:12845
+property_value: skos:narrowMatch RHEA:63560
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28557" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008242
@@ -81001,10 +83975,19 @@
def: "Catalysis of the cleavage of non-standard peptide bonds releasing substituted amino acids such as pyroglutamate or cleave isopeptide bonds, such as many deubiquitinating enzymes." [EC:3.4.19.-, PMID:20157488, PMID:9920379]
synonym: "peptidase activity, acting on peptides containing modified amino acids" RELATED []
xref: EC:3.4.19.-
-xref: Reactome:R-HSA-5696365 "ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH"
+xref: EC:3.4.19.1
+xref: EC:3.4.19.2
+xref: MetaCyc:ACYLAMINOACYL-PEPTIDASE-RXN
+xref: MetaCyc:PEPTIDYL-GLYCINAMIDASE-RXN
is_a: GO:0008233 ! peptidase activity
+property_value: skos:exactMatch EC:3.4.19.-
+property_value: skos:narrowMatch EC:3.4.19.1
+property_value: skos:narrowMatch EC:3.4.19.2
+property_value: skos:narrowMatch MetaCyc:ACYLAMINOACYL-PEPTIDASE-RXN
+property_value: skos:narrowMatch MetaCyc:PEPTIDYL-GLYCINAMIDASE-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20581" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008243
@@ -81121,6 +84104,8 @@
synonym: "nucleotide-specific phosphatase activity" RELATED []
xref: RHEA:22140
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch RHEA:22140
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008253
@@ -81160,6 +84145,9 @@
xref: Reactome:R-HSA-9755078 "NT5C2 tetramer dephosphorylates RBV-MP"
xref: RHEA:12484
is_a: GO:0008252 ! nucleotidase activity
+property_value: skos:exactMatch EC:3.1.3.5
+property_value: skos:exactMatch RHEA:12484
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008254
@@ -81175,6 +84163,9 @@
xref: MetaCyc:3-NUCLEOTID-RXN
xref: RHEA:10144
is_a: GO:0008252 ! nucleotidase activity
+property_value: skos:exactMatch EC:3.1.3.6
+property_value: skos:exactMatch RHEA:10144
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008255
@@ -81195,6 +84186,9 @@
xref: MetaCyc:2.7.13.1-RXN
xref: RHEA:22720
is_a: GO:0004673 ! protein histidine kinase activity
+property_value: skos:exactMatch EC:2.7.13.1
+property_value: skos:exactMatch RHEA:22720
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008257
@@ -81208,6 +84202,9 @@
xref: MetaCyc:2.7.13.2-RXN
xref: RHEA:11860
is_a: GO:0004673 ! protein histidine kinase activity
+property_value: skos:exactMatch EC:2.7.13.2
+property_value: skos:exactMatch RHEA:11860
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008258
@@ -81251,8 +84248,13 @@
xref: MetaCyc:3-OXOACID-COA-TRANSFERASE-RXN
xref: Reactome:R-HSA-74177 "OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA"
xref: RHEA:24564
+xref: RHEA:25480
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.5
+property_value: skos:exactMatch RHEA:24564
+property_value: skos:narrowMatch RHEA:25480
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23466" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2022-06-10T14:37:09Z
@@ -81285,6 +84287,8 @@
xref: Reactome:R-HSA-947499 "Exchange of oxygen with sulfur in MoCo"
xref: RHEA:42636
is_a: GO:0016783 ! sulfurtransferase activity
+property_value: skos:exactMatch EC:2.8.1.9
+property_value: skos:exactMatch RHEA:42636
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -81368,7 +84372,9 @@
xref: RHEA:69967
is_a: GO:0005432 ! calcium:sodium antiporter activity
is_a: GO:0022821 ! solute:potassium antiporter activity
+property_value: skos:exactMatch RHEA:69967
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008275
@@ -81537,6 +84543,7 @@
def: "Combining with a protein bride of sevenless (boss) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate." [GOC:jl, GOC:signaling]
synonym: "sevenless receptor activity" RELATED []
is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -81618,8 +84625,16 @@
synonym: "spermidine biosynthesis" EXACT []
synonym: "spermidine formation" EXACT []
synonym: "spermidine synthesis" EXACT []
+xref: MetaCyc:BSUBPOLYAMSYN-PWY
+xref: MetaCyc:PWY-6559
+xref: MetaCyc:PWY-6834
+xref: MetaCyc:PWY2PN3-14
is_a: GO:0006596 ! polyamine biosynthetic process
is_a: GO:0008216 ! spermidine metabolic process
+property_value: skos:narrowMatch MetaCyc:BSUBPOLYAMSYN-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-6559
+property_value: skos:narrowMatch MetaCyc:PWY-6834
+property_value: skos:narrowMatch MetaCyc:PWY2PN3-14
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -81797,7 +84812,9 @@
xref: MetaCyc:3.1.11.1-RXN
is_a: GO:0008296 ! 3'-5'-DNA exonuclease activity
is_a: GO:0008297 ! single-stranded DNA exodeoxyribonuclease activity
+property_value: skos:exactMatch EC:3.1.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008311
@@ -81812,7 +84829,9 @@
xref: MetaCyc:3.1.11.2-RXN
is_a: GO:0008296 ! 3'-5'-DNA exonuclease activity
is_a: GO:0008309 ! double-stranded DNA exodeoxyribonuclease activity
+property_value: skos:exactMatch EC:3.1.11.2
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008312
@@ -81881,6 +84900,7 @@
def: "Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein." [GOC:mah]
is_a: GO:0004659 ! prenyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:broadMatch EC:2.5.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
[Term]
@@ -81921,7 +84941,6 @@
xref: Reactome:R-HSA-9636375 "SecA2 transports SapM from cytoplasm to cytosol"
xref: Reactome:R-HSA-9698930 "HCMV C Nucleocapsid Translocation"
xref: Reactome:R-HSA-9698933 "HCMV B Nucleocapsid Translocation"
-xref: Reactome:R-HSA-9760705 "GspD2:GspC2:GspS2 transports LT from periplasmic to extracellular space"
is_a: GO:0022884 ! macromolecule transmembrane transporter activity
is_a: GO:0140318 ! protein transporter activity
relationship: part_of GO:0071806 ! protein transmembrane transport
@@ -82039,6 +85058,9 @@
xref: Reactome:R-HSA-71261 "BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA"
xref: RHEA:24028
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.1
+property_value: skos:exactMatch RHEA:24028
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008337
@@ -82213,6 +85235,9 @@
xref: RHEA:10216
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0140994 ! RNA polymerase II CTD heptapeptide repeat modifying activity
+property_value: skos:exactMatch EC:2.7.11.23
+property_value: skos:exactMatch RHEA:10216
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008354
@@ -82376,6 +85401,8 @@
xref: Reactome:R-HSA-981814 "ST6GALNAC2 transfers sialic acid to Core 1 mucins"
xref: Wikipedia:Sialyltransferase
is_a: GO:0016757 ! glycosyltransferase activity
+property_value: skos:exactMatch EC:2.4.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008374
@@ -82401,8 +85428,8 @@
namespace: molecular_function
def: "Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar." [ISBN:0198506732]
synonym: "GlcNAc transferase activity" EXACT []
-xref: Reactome:R-HSA-5617037 "POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1"
xref: Reactome:R-HSA-5694487 "A4GNT transfers GlcNAc to core 2 mucins"
+xref: Reactome:R-HSA-8879117 "POMGNT2 transfers GlcNAc to Man-DAG1"
xref: Reactome:R-HSA-9683648 "Spike trimer glycoside chains are extended"
xref: Reactome:R-HSA-9694656 "Spike trimer glycoside chains are extended"
is_a: GO:0008194 ! UDP-glycosyltransferase activity
@@ -82457,8 +85484,10 @@
xref: Reactome:R-HSA-3697894 "PRDX5 reduces peroxynitrite to nitrite using TXN2"
xref: RHEA:63528
is_a: GO:0140824 ! thioredoxin-dependent peroxiredoxin activity
+property_value: skos:exactMatch RHEA:63528
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22598" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23121" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008380
@@ -82512,6 +85541,9 @@
xref: RHEA:19073
is_a: GO:0004674 ! protein serine/threonine kinase activity
relationship: part_of GO:0007252 ! I-kappaB phosphorylation
+property_value: skos:exactMatch EC:2.7.11.10
+property_value: skos:exactMatch RHEA:19073
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008385
@@ -82554,6 +85586,9 @@
xref: RHEA:35739
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.15.6
+property_value: skos:exactMatch RHEA:35739
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008387
@@ -82574,6 +85609,7 @@
xref: RHEA:83179
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch RHEA:83179
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29066" xsd:anyURI
[Term]
@@ -82600,6 +85636,7 @@
xref: RHEA:53196
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:53196
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29041" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29078" xsd:anyURI
@@ -82660,6 +85697,7 @@
xref: Reactome:R-HSA-9035960 "Defective CYP27A1 does not 27-hydroxylate 5-CHOL3,7,24(s)-triol"
xref: Reactome:R-HSA-9758674 "CYP3A4 oxidizes PREDN,PREDL"
is_a: GO:0004497 ! monooxygenase activity
+property_value: skos:broadMatch EC:1.-.-.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29311" xsd:anyURI
[Term]
@@ -82674,6 +85712,7 @@
xref: Reactome:R-HSA-5602885 "Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL"
xref: RHEA:68740
is_a: GO:0008387 ! steroid 7-alpha-hydroxylase activity
+property_value: skos:exactMatch RHEA:68740
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29041" xsd:anyURI
[Term]
@@ -82683,13 +85722,25 @@
def: "Catalysis of the reaction: a steroid + reduced [NADPH--hemoprotein reductase] + O2 = a 12-alpha-hydroxysteroid + oxidized [NADPH--hemoprotein reductase]- H2O +H+." [EC:1.14.14.139]
synonym: "cytochrome P450 CYP8B1" NARROW []
xref: EC:1.14.14.139
-xref: Reactome:R-HSA-192157 "CYP8B1 12-hydroxylates 4CHOL7aOLONE"
-xref: Reactome:R-HSA-193709 "CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL"
-xref: Reactome:R-HSA-193845 "CYP8B1 12-hydroxylates 4CHOL7a,27DONE"
+xref: KEGG_REACTION:R04826
+xref: KEGG_REACTION:R07204
+xref: MetaCyc:1.14.13.95-RXN
+xref: MetaCyc:1.14.13.96-RXN
+xref: RHEA:15261
xref: RHEA:46752
+xref: RHEA:65700
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.139
+property_value: skos:exactMatch RHEA:46752
+property_value: skos:narrowMatch KEGG_REACTION:R04826
+property_value: skos:narrowMatch KEGG_REACTION:R07204
+property_value: skos:narrowMatch MetaCyc:1.14.13.95-RXN
+property_value: skos:narrowMatch MetaCyc:1.14.13.96-RXN
+property_value: skos:narrowMatch RHEA:15261
+property_value: skos:narrowMatch RHEA:65700
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24843" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008398
@@ -82706,11 +85757,17 @@
synonym: "sterol 14alpha-demethylase activity" RELATED []
xref: EC:1.14.14.154
xref: MetaCyc:1.14.13.70-RXN
-xref: Reactome:R-HSA-9947148 "CYP51A1 14-demethylates 24,25-dhLAN to 4,4-diMeCholesta-8,14-dien-3-ol"
+xref: RHEA:14917
+xref: RHEA:25286
xref: RHEA:54028
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
is_a: GO:0032451 ! demethylase activity
+property_value: skos:exactMatch EC:1.14.14.154
+property_value: skos:exactMatch RHEA:54028
+property_value: skos:narrowMatch RHEA:14917
+property_value: skos:narrowMatch RHEA:25286
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22523" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008399
@@ -82748,7 +85805,9 @@
xref: RHEA:24968
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
is_a: GO:0070576 ! vitamin D 24-hydroxylase activity
+property_value: skos:exactMatch RHEA:24968
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28340" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008404
@@ -82760,6 +85819,8 @@
synonym: "cytochrome P450 CYP2C39" NARROW []
xref: RHEA:51472
is_a: GO:0008392 ! arachidonate epoxygenase activity
+property_value: skos:exactMatch RHEA:51472
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008405
@@ -82770,7 +85831,9 @@
synonym: "cytochrome P450 CYP2C38" NARROW []
xref: RHEA:51480
is_a: GO:0008392 ! arachidonate epoxygenase activity
+property_value: skos:exactMatch RHEA:51480
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28648" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008406
@@ -82813,9 +85876,11 @@
id: GO:0008410
name: CoA-transferase activity
namespace: molecular_function
-def: "Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor)." [GOC:jl]
+def: "Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor)." [EC:2.8.3.-]
xref: EC:2.8.3.-
is_a: GO:0016782 ! transferase activity, transferring sulphur-containing groups
+property_value: skos:exactMatch EC:2.8.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008411
@@ -82842,9 +85907,11 @@
synonym: "PHB polyprenyl diphosphate transferase activity" EXACT []
xref: EC:2.5.1.39
xref: MetaCyc:RXN-11368
-xref: Reactome:R-HSA-2162192 "COQ2 ligates all-E-10PrP2 to PHB"
xref: RHEA:44504
is_a: GO:0004659 ! prenyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.39
+property_value: skos:exactMatch MetaCyc:RXN-11368
+property_value: skos:exactMatch RHEA:44504
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26830" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29428" xsd:anyURI
@@ -82861,6 +85928,9 @@
xref: EC:3.6.1.69
xref: RHEA:60032
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:exactMatch EC:3.6.1.69
+property_value: skos:exactMatch RHEA:60032
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008414
@@ -82878,8 +85948,6 @@
def: "Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [GOC:ai]
xref: Reactome:R-HSA-9033949 "FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC"
xref: Reactome:R-HSA-9846332 "FUT1,2 transfer fucose to gangliosides"
-xref: Reactome:R-HSA-9935449 "FUT10 O-fucosylates EMI domain-containing proteins"
-xref: Reactome:R-HSA-9935469 "FUT11 O-fucosylates EMI domain-containing proteins"
is_a: GO:0016758 ! hexosyltransferase activity
[Term]
@@ -82890,7 +85958,10 @@
xref: EC:3.5.1.121
xref: RHEA:50676
is_a: GO:0160260 ! protein asparagine deamidase activity
+property_value: skos:exactMatch EC:3.5.1.121
+property_value: skos:exactMatch RHEA:50676
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23342" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008419
@@ -82899,6 +85970,7 @@
def: "Catalysis of the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide." [PMID:7519612]
xref: EC:3.1.26.1
is_a: GO:0016891 ! RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
+property_value: skos:exactMatch EC:3.1.26.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -82926,6 +85998,9 @@
xref: MetaCyc:3.5.1.55-RXN
xref: RHEA:17517
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.55
+property_value: skos:exactMatch RHEA:17517
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008422
@@ -82955,7 +86030,12 @@
synonym: "salicilinase activity" NARROW []
xref: EC:3.2.1.21
xref: MetaCyc:3.2.1.21-RXN
+xref: RHEA:69647
+xref: RHEA:69655
is_a: GO:0015926 ! glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.21
+property_value: skos:narrowMatch RHEA:69647
+property_value: skos:narrowMatch RHEA:69655
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22612" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22613" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25793" xsd:anyURI
@@ -82995,6 +86075,9 @@
is_a: GO:0046921 ! alpha-(1->6)-fucosyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
relationship: part_of GO:0036066 ! protein O-linked glycosylation via fucose
+property_value: skos:exactMatch EC:2.4.1.68
+property_value: skos:exactMatch RHEA:12985
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008425
@@ -83013,9 +86096,12 @@
xref: RHEA:28286
is_a: GO:0008169 ! C-methyltransferase activity
relationship: part_of GO:0006744 ! ubiquinone biosynthetic process
+property_value: skos:exactMatch EC:2.1.1.201
+property_value: skos:exactMatch RHEA:28286
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25591" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25682" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29420" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008426
@@ -83053,7 +86139,6 @@
name: phosphatidylethanolamine binding
namespace: molecular_function
def: "Binding to a phosphatidylethanolamine, a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine." [ISBN:0198506732]
-xref: Reactome:R-HSA-9842115 "PSAP(195-273) dimer binds PE"
is_a: GO:0005543 ! phospholipid binding
[Term]
@@ -83151,6 +86236,11 @@
xref: Reactome:R-HSA-1855233 "I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus"
xref: RHEA:11020
is_a: GO:0051766 ! inositol trisphosphate kinase activity
+property_value: skos:broadMatch EC:2.7.1.151
+property_value: skos:exactMatch EC:2.7.1.127
+property_value: skos:exactMatch KEGG_REACTION:R03433
+property_value: skos:exactMatch MetaCyc:2.7.1.127-RXN
+property_value: skos:exactMatch RHEA:11020
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
[Term]
@@ -83170,6 +86260,9 @@
xref: Reactome:R-HSA-8953499 "IMPAD1 hydrolyses PAP to AMP"
xref: RHEA:10040
is_a: GO:0008252 ! nucleotidase activity
+property_value: skos:exactMatch EC:3.1.3.7
+property_value: skos:exactMatch RHEA:10040
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008442
@@ -83182,6 +86275,9 @@
xref: Reactome:R-HSA-70885 "beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+"
xref: RHEA:17681
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.31
+property_value: skos:exactMatch RHEA:17681
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008443
@@ -83219,6 +86315,9 @@
xref: Reactome:R-HSA-1482939 "CDP-DAG is converted to PGP by PGS1"
xref: RHEA:12593
is_a: GO:0017169 ! CDP-alcohol phosphatidyltransferase activity
+property_value: skos:exactMatch EC:2.7.8.5
+property_value: skos:exactMatch RHEA:12593
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008445
@@ -83232,7 +86331,11 @@
xref: Reactome:R-HSA-6810076 "DDO oxidizes D-Asp to OA"
xref: RHEA:12512
is_a: GO:0003884 ! D-amino-acid oxidase activity
+property_value: skos:broadMatch MetaCyc:D-ASPARTATE-OXIDASE-RXN
+property_value: skos:exactMatch EC:1.4.3.1
+property_value: skos:exactMatch RHEA:12512
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008446
@@ -83254,6 +86357,9 @@
xref: Reactome:R-HSA-6787632 "GMDS dehydrates GDP-Man to GDP-DHDMan"
xref: RHEA:23820
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.47
+property_value: skos:exactMatch RHEA:23820
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008447
@@ -83274,7 +86380,10 @@
xref: MetaCyc:RXN-3541
xref: RHEA:30243
is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.10.3.3
+property_value: skos:exactMatch RHEA:30243
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21022" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008448
@@ -83291,6 +86400,8 @@
xref: RHEA:22936
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0019213 ! deacetylase activity
+property_value: skos:exactMatch EC:3.5.1.25
+property_value: skos:exactMatch RHEA:22936
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -83308,9 +86419,11 @@
synonym: "O,N-disulfate O-sulfohydrolase activity" RELATED [EC:3.1.6.14]
xref: EC:3.1.6.14
xref: MetaCyc:3.1.6.14-RXN
-xref: Reactome:R-HSA-1638032 "GNS:Ca2+ cleaves sulfate from GlcNAc-6-sulfate units of keratan sulfate"
+xref: Reactome:R-HSA-1638032 "N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate"
xref: Reactome:R-HSA-2263495 "Defective GNS does not hydrolyse 6-sulfate from GlcNAc6S"
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.14
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008450
@@ -83368,6 +86481,9 @@
xref: Reactome:R-HSA-904864 "Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate"
xref: RHEA:24248
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.44
+property_value: skos:exactMatch RHEA:24248
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008454
@@ -83390,6 +86506,9 @@
xref: RHEA:16057
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.145
+property_value: skos:exactMatch RHEA:16057
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008455
@@ -83419,6 +86538,9 @@
xref: RHEA:12941
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.143
+property_value: skos:exactMatch RHEA:12941
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008456
@@ -83435,6 +86557,9 @@
xref: MetaCyc:3.2.1.49-RXN
xref: RHEA:15085
is_a: GO:0015929 ! hexosaminidase activity
+property_value: skos:exactMatch EC:3.2.1.49
+property_value: skos:exactMatch RHEA:15085
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008457
@@ -83464,6 +86589,8 @@
xref: Reactome:R-HSA-390281 "4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH"
xref: RHEA:17177
is_a: GO:0016406 ! carnitine O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.137
+property_value: skos:exactMatch RHEA:17177
[Term]
id: GO:0008459
@@ -83482,7 +86609,10 @@
xref: Reactome:R-HSA-3595175 "Defective CHST3 does not transfer SO4(2-) to chondroitin"
xref: RHEA:11108
is_a: GO:0034481 ! chondroitin sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.17
+property_value: skos:exactMatch RHEA:11108
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008460
@@ -83500,6 +86630,9 @@
xref: MetaCyc:DTDPGLUCDEHYDRAT-RXN
xref: RHEA:17221
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.46
+property_value: skos:exactMatch RHEA:17221
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008462
@@ -83528,6 +86661,9 @@
xref: MetaCyc:FORMYLMETHIONINE-DEFORMYLASE-RXN
xref: RHEA:17781
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.31
+property_value: skos:exactMatch RHEA:17781
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008464
@@ -83551,7 +86687,10 @@
xref: MetaCyc:GLYCERATE-DEHYDROGENASE-RXN
xref: RHEA:17905
is_a: GO:0016618 ! hydroxypyruvate reductase [NAD(P)H] activity
+property_value: skos:exactMatch EC:1.1.1.29
+property_value: skos:exactMatch RHEA:17905
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25789" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008466
@@ -83566,12 +86705,21 @@
synonym: "UDP-alpha-D-glucose:glycogenin alpha-D-glucosyltransferase activity" RELATED [EC:2.4.1.186]
synonym: "UDP-glucose:glycogenin glucosyltransferase activity" RELATED [EC:2.4.1.186]
xref: EC:2.4.1.186
+xref: MetaCyc:GLYCOGENIN-GLUCOSYLTRANSFERASE-RXN
+xref: MetaCyc:RXN-7667
xref: Reactome:R-HSA-3322003 "Autoglucosylation of GYG1 complexed with GYS1-b"
xref: Reactome:R-HSA-3322014 "Autoglucosylation of GYG2 complexed with GYS2-a"
xref: Reactome:R-HSA-3322019 "Autoglucosylation of GYG2 complexed with GYS2-b"
xref: Reactome:R-HSA-3322025 "Autoglucosylation of GYG1 complexed with GYS1-a"
xref: Reactome:R-HSA-3814838 "Defective GYG1 is not autoglucosyolated"
+xref: RHEA:23360
+xref: RHEA:56560
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.186
+property_value: skos:narrowMatch MetaCyc:GLYCOGENIN-GLUCOSYLTRANSFERASE-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-7667
+property_value: skos:narrowMatch RHEA:23360
+property_value: skos:narrowMatch RHEA:56560
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -83589,10 +86737,23 @@
synonym: "heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity" RELATED []
synonym: "heparin-glucosamine 3-O-sulfotransferase activity" RELATED []
synonym: "heparin-glucosamine 3-O-sulphotransferase activity" RELATED []
+xref: EC:2.8.2.23
+xref: EC:2.8.2.29
+xref: EC:2.8.2.30
+xref: MetaCyc:2.8.2.23-RXN
+xref: MetaCyc:2.8.2.29-RXN
+xref: MetaCyc:2.8.2.30-RXN
xref: Reactome:R-HSA-2076383 "HS3ST1 sulfates GlcN at C3 in heparan sulfate"
-xref: Reactome:R-HSA-2076611 "HS3ST2-6 sulfate GlcN at C3 in heparan sulfate"
+xref: Reactome:R-HSA-2076611 "HS3STs sulfate GlcN at C3 in heparan sulfate"
xref: RHEA:15461
is_a: GO:0034483 ! heparan sulfate sulfotransferase activity
+property_value: skos:exactMatch RHEA:15461
+property_value: skos:narrowMatch EC:2.8.2.23
+property_value: skos:narrowMatch EC:2.8.2.29
+property_value: skos:narrowMatch EC:2.8.2.30
+property_value: skos:narrowMatch MetaCyc:2.8.2.23-RXN
+property_value: skos:narrowMatch MetaCyc:2.8.2.29-RXN
+property_value: skos:narrowMatch MetaCyc:2.8.2.30-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28380" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28762" xsd:anyURI
@@ -83626,8 +86787,11 @@
xref: Reactome:R-HSA-9914837 "IVD mutants don't synthesize beta-methylcrotonyl-CoA"
xref: RHEA:12276
is_a: GO:0016937 ! short-chain fatty acyl-CoA dehydrogenase activity
+property_value: skos:exactMatch EC:1.3.8.4
+property_value: skos:exactMatch RHEA:12276
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23497" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26438" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008471
@@ -83670,6 +86834,9 @@
xref: MetaCyc:ORNITHINE-CYCLODEAMINASE-RXN
xref: RHEA:24368
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.12
+property_value: skos:exactMatch RHEA:24368
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008474
@@ -83691,6 +86858,9 @@
is_a: GO:0016790 ! thiolester hydrolase activity
is_a: GO:0098599 ! palmitoyl hydrolase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:3.1.2.22
+property_value: skos:exactMatch RHEA:19233
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008475
@@ -83714,7 +86884,10 @@
xref: RHEA:16569
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:1.14.11.4
+property_value: skos:exactMatch RHEA:16569
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29801" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008476
@@ -83733,6 +86906,9 @@
xref: RHEA:16801
is_a: GO:0008146 ! sulfotransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.8.2.20
+property_value: skos:exactMatch RHEA:16801
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008477
@@ -83758,6 +86934,9 @@
xref: MetaCyc:PURINE-NUCLEOSIDASE-RXN
xref: RHEA:23344
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.2.1
+property_value: skos:exactMatch RHEA:23344
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008478
@@ -83780,6 +86959,9 @@
xref: RHEA:10224
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.35
+property_value: skos:exactMatch RHEA:10224
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008479
@@ -83798,11 +86980,14 @@
synonym: "tRNA-guanosine(34) queuine transglycosylase" EXACT [EC:2.4.2.64]
xref: EC:2.4.2.64
xref: MetaCyc:QUEUOSINE-TRNA-RIBOSYLTRANSFERASE-RXN
-xref: Reactome:R-HSA-6782443 "QTRT1:QTRTD1 exchanges guanine for queuine at guanosine-34 of tRNA(Asn),tRNA(Asp),tRNA(His),tRNA(Tyr) yielding queuosine-34 tRNA(Asn),tRNA(Asp),tRNA(His),tRNA(Tyr)"
+xref: Reactome:R-HSA-6782443 "QTRT1:QTRTD1 exchange guanine for queuosine at guanosine-34 of tRNA(Tyr)"
xref: RHEA:16633
is_a: GO:0016763 ! pentosyltransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.4.2.64
+property_value: skos:exactMatch RHEA:16633
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25797" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008480
@@ -83820,6 +87005,9 @@
xref: Reactome:R-HSA-6797913 "SARDH:FAD oxidatively demethylates SARC to Gly"
xref: RHEA:19793
is_a: GO:0046997 ! oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor
+property_value: skos:exactMatch EC:1.5.8.3
+property_value: skos:exactMatch RHEA:19793
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008481
@@ -83834,11 +87022,11 @@
synonym: "sphingosine kinase (phosphorylating)" RELATED [EC:2.7.1.91]
xref: EC:2.7.1.91
xref: MetaCyc:SPHINGANINE-KINASE-RXN
-xref: Reactome:R-HSA-5218845 "p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate"
-xref: Reactome:R-HSA-9625814 "SPHK1 phosphorylates sphingosine in response to E2 stimulation"
xref: RHEA:51496
is_a: GO:0001727 ! lipid kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.91
+property_value: skos:exactMatch RHEA:51496
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -83855,6 +87043,11 @@
xref: Reactome:R-HSA-1614544 "Sulfite is oxidized to sulfate"
xref: RHEA:24600
is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.8.3.1
+property_value: skos:exactMatch KEGG_REACTION:R00533
+property_value: skos:exactMatch MetaCyc:SULFITE-OXIDASE-RXN
+property_value: skos:exactMatch RHEA:24600
+property_value: skos:relatedMatch MetaCyc:PWY-5326
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -83866,6 +87059,8 @@
xref: EC:2.6.1.-
xref: Reactome:R-HSA-1237102 "Transamination of MOB to methionine"
is_a: GO:0016769 ! transferase activity, transferring nitrogenous groups
+property_value: skos:exactMatch EC:2.6.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008484
@@ -83876,7 +87071,9 @@
synonym: "sulphuric ester hydrolase activity" EXACT []
xref: EC:3.1.6.-
is_a: GO:0016788 ! hydrolase activity, acting on ester bonds
+property_value: skos:exactMatch EC:3.1.6.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25774" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008486
@@ -83891,6 +87088,8 @@
xref: KEGG_REACTION:R05777
xref: MetaCyc:3.6.1.52-RXN
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.52
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008487
@@ -83920,6 +87119,9 @@
xref: Reactome:R-HSA-9673231 "GGCX does not gamma-carboxylate 3D-F9(29-461) (pro-factor IX)"
xref: RHEA:45140
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.90
+property_value: skos:exactMatch RHEA:45140
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008489
@@ -83934,7 +87136,10 @@
xref: Reactome:R-HSA-9851347 "B4GALT5/6 transfer Gal to GlcCer"
xref: RHEA:31495
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.274
+property_value: skos:exactMatch RHEA:31495
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25286" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008490
@@ -83991,6 +87196,9 @@
xref: Reactome:R-HSA-2995330 "COX10 transforms heme to heme O"
xref: RHEA:28070
is_a: GO:0004659 ! prenyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.141
+property_value: skos:exactMatch RHEA:28070
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008496
@@ -84008,6 +87216,8 @@
xref: MetaCyc:3.2.1.101-RXN
xref: Reactome:R-HSA-6799581 "MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man"
is_a: GO:0004559 ! alpha-mannosidase activity
+property_value: skos:exactMatch EC:3.2.1.101
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008498
@@ -84031,11 +87241,16 @@
synonym: "UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity" EXACT []
xref: EC:2.4.1.86
xref: MetaCyc:2.4.1.86-RXN
+xref: Reactome:R-HSA-914010 "Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein"
xref: Reactome:R-HSA-9603989 "B3GALTs transfer Gal to GlcNAc-1,3-Gal-R to form Type 1 chain"
xref: Reactome:R-HSA-9845516 "B3GALT4 transfers Gal to gangliosides"
+xref: RHEA:16045
xref: RHEA:53432
is_a: GO:0035250 ! UDP-galactosyltransferase activity
is_a: GO:0048531 ! beta-1,3-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.86
+property_value: skos:exactMatch RHEA:53432
+property_value: skos:narrowMatch RHEA:16045
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29103" xsd:anyURI
[Term]
@@ -84072,9 +87287,10 @@
alt_id: GO:0015201
def: "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other." [GOC:mah]
xref: Reactome:R-HSA-372542 "Loading of dopamine into synaptic veiscles"
-xref: Reactome:R-HSA-379393 "SLC6A3 cotransports DA, Na+, Cl- from extracellular region to cytosol"
+xref: Reactome:R-HSA-379393 "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol"
xref: Reactome:R-HSA-380586 "loading of Serotonin in synaptic vesicles"
xref: Reactome:R-HSA-380620 "Reuptake of serotonin from the synapse"
+xref: Reactome:R-HSA-444160 "VMAT1/2 can mediate the transport of biogenic amines"
xref: Reactome:R-HSA-5660706 "Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol"
is_a: GO:0022804 ! active transmembrane transporter activity
relationship: part_of GO:0015844 ! monoamine transport
@@ -84090,7 +87306,9 @@
xref: RHEA:72187
is_a: GO:0005351 ! carbohydrate:proton symporter activity
is_a: GO:0009669 ! sucrose:monoatomic cation symporter activity
+property_value: skos:exactMatch RHEA:72187
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008507
@@ -84141,8 +87359,10 @@
xref: RHEA:70267
is_a: GO:0015370 ! solute:sodium symporter activity
is_a: GO:0140410 ! monoatomic cation:bicarbonate symporter activity
+property_value: skos:exactMatch RHEA:70267
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26780" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008511
@@ -84156,7 +87376,9 @@
is_a: GO:0009674 ! potassium:sodium symporter activity
is_a: GO:0015378 ! sodium:chloride symporter activity
is_a: GO:0015379 ! potassium:chloride symporter activity
+property_value: skos:exactMatch RHEA:72395
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008512
@@ -84169,7 +87391,9 @@
xref: RHEA:28574
is_a: GO:0008271 ! secondary active sulfate transmembrane transporter activity
is_a: GO:0015295 ! solute:proton symporter activity
+property_value: skos:exactMatch RHEA:28574
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008513
@@ -84192,7 +87416,7 @@
def: "OBSOLETE. Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai]
comment: he reason for obsoletion is that this term was an unnecessary and confusing grouping term.
xref: Reactome:R-HSA-2142859 "Growing HA is extruded from the cell by ABCC5"
-xref: Reactome:R-HSA-561041 "OAT1,2,3 transport organic anions with antiport of dicarboxylic acids"
+xref: Reactome:R-HSA-561041 "OAT1-3 transport organic anions with antiport of dicarboxylic acids"
xref: Reactome:R-HSA-9794830 "SLC22A8 transports Cipro into renal cell"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30715" xsd:anyURI
is_obsolete: true
@@ -84227,10 +87451,11 @@
synonym: "folic acid transporter activity" RELATED []
synonym: "vitamin B9 transporter activity" EXACT []
synonym: "vitamin M transporter activity" EXACT []
+xref: Reactome:R-HSA-200646 "Cytosolic folate export across the plasma membrane"
xref: Reactome:R-HSA-200652 "SLC19A1 transports 5-methyl-THF from extracellular region to cytosol"
xref: Reactome:R-HSA-200680 "SLC25A32 transports THF from cytosol to mitochondrial matrix"
xref: Reactome:R-HSA-200720 "SLC25A32 transports THF from mitochondrial matrix to cytosol"
-is_a: GO:0042887 ! amide transmembrane transporter activity
+xref: Reactome:R-HSA-200729 "SLC46A1 transports FOLA from extracellular region to cytosol"
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
is_a: GO:0072349 ! modified amino acid transmembrane transporter activity
is_a: GO:0090482 ! vitamin transmembrane transporter activity
@@ -84289,7 +87514,9 @@
is_a: GO:0005402 ! carbohydrate:monoatomic cation symporter activity
is_a: GO:0015145 ! monosaccharide transmembrane transporter activity
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
+property_value: skos:exactMatch RHEA:69883
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2009-09-01T02:25:22Z
@@ -84303,7 +87530,6 @@
xref: Reactome:R-HSA-727759 "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen"
is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity
is_a: GO:0015932 ! nucleobase-containing compound transmembrane transporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:1901682 ! sulfur compound transmembrane transporter activity
relationship: part_of GO:0015876 ! acetyl-CoA transport
@@ -84404,6 +87630,9 @@
xref: RHEA:14357
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.26
+property_value: skos:exactMatch RHEA:14357
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008532
@@ -84422,10 +87651,14 @@
synonym: "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase" BROAD [EC:2.4.1.149]
xref: EC:2.4.1.149
xref: MetaCyc:2.4.1.149-RXN
+xref: MetaCyc:2.4.1.163-RXN
xref: Reactome:R-HSA-2025724 "B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG"
-xref: Reactome:R-HSA-9931297 "B3GNT3 mediated CD274 glycosylation in Golgi"
xref: RHEA:14389
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.149
+property_value: skos:exactMatch MetaCyc:2.4.1.149-RXN
+property_value: skos:exactMatch RHEA:14389
+property_value: skos:narrowMatch MetaCyc:2.4.1.163-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -84469,6 +87702,8 @@
xref: Reactome:R-HSA-110243 "Excision of 8-oxoguanine by OGG1 glycosylase"
xref: Reactome:R-HSA-110244 "Excision of FapyG by OGG1 glycosylase"
is_a: GO:0000702 ! oxidized base lesion DNA N-glycosylase activity
+property_value: skos:exactMatch EC:3.2.2.23
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008535
@@ -84567,6 +87802,7 @@
xref: Reactome:R-HSA-168162 "Phosphorylation of human JNKs by activated MKK4/MKK7"
is_a: GO:0004708 ! MAP kinase kinase activity
relationship: part_of GO:0007254 ! JNK cascade
+property_value: skos:broadMatch EC:2.7.12.2
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -84615,7 +87851,6 @@
synonym: "dynamine GTPase activity" EXACT []
is_obsolete: true
replaced_by: GO:0003924
-consider: GO:0006897
[Term]
id: GO:0008550
@@ -84646,8 +87881,11 @@
is_a: GO:0015086 ! cadmium ion transmembrane transporter activity
is_a: GO:0015662 ! P-type ion transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
+property_value: skos:exactMatch EC:7.2.2.21
+property_value: skos:exactMatch RHEA:12132
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008552
@@ -84689,6 +87927,9 @@
is_a: GO:0015078 ! proton transmembrane transporter activity
is_a: GO:0015662 ! P-type ion transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
+property_value: skos:exactMatch EC:7.1.2.1
+property_value: skos:exactMatch RHEA:20852
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-09-30T16:56:16Z
@@ -84712,6 +87953,9 @@
is_a: GO:0015081 ! sodium ion transmembrane transporter activity
is_a: GO:0015662 ! P-type ion transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
+property_value: skos:broadMatch MetaCyc:RXN-17739
+property_value: skos:broadMatch RHEA:14633
+property_value: skos:exactMatch EC:7.2.2.3
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21796" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
@@ -84740,8 +87984,11 @@
is_a: GO:0015079 ! potassium ion transmembrane transporter activity
is_a: GO:0015662 ! P-type ion transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
+property_value: skos:exactMatch EC:7.2.2.6
+property_value: skos:exactMatch RHEA:16777
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27695" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008558
@@ -84757,6 +88004,9 @@
xref: RHEA:20832
is_a: GO:0015208 ! guanine transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.6.2.6
+property_value: skos:exactMatch RHEA:20832
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008559
@@ -84779,9 +88029,11 @@
xref: EC:7.6.2.2
xref: MetaCyc:3.6.3.44-RXN
xref: Reactome:R-HSA-9757139 "ABCB1,ABCC2 transport ATVs from cytosol to extracellular region"
-xref: Reactome:R-HSA-9911514 "MacA:MacB:TolC transports azithromycin from the cytosol to the periplasm"
+xref: RHEA:33147
is_a: GO:0042910 ! xenobiotic transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.6.2.2
+property_value: skos:narrowMatch RHEA:33147
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28557" xsd:anyURI
[Term]
@@ -84803,9 +88055,8 @@
synonym: "ATPase-coupled protein transporter activity" EXACT []
xref: EC:7.4.2.8
xref: MetaCyc:3.6.3.50-RXN
-xref: Reactome:R-HSA-9760310 "SecA:SecYEG transports proteins from cytosol to periplasmic space"
-xref: Reactome:R-HSA-9926041 "HlyB:HlyD:TolC transports HlyA from cytosol to periplasm"
is_a: GO:0015450 ! protein-transporting ATPase activity
+property_value: skos:exactMatch EC:7.4.2.8
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
@@ -84833,6 +88084,8 @@
intersection_of: GO:0015450 ! protein-transporting ATPase activity
intersection_of: occurs_in GO:0005739 ! mitochondrion
relationship: occurs_in GO:0005739 ! mitochondrion
+property_value: skos:exactMatch EC:7.4.2.3
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008567
@@ -84862,8 +88115,10 @@
is_a: GO:0140657 ! ATP-dependent activity
is_a: GO:0170060 ! microtubule destabilizing activity
relationship: part_of GO:0000226 ! microtubule cytoskeleton organization
+property_value: skos:exactMatch EC:5.6.1.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23065" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29690" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008569
@@ -84877,7 +88132,15 @@
synonym: "microtubule motor activity, minus-end-directed" EXACT []
synonym: "minus-end-directed ATP-dependent microtubule motor activity" EXACT []
synonym: "minus-end-directed kinesin ATPase activity" NARROW []
+xref: EC:5.6.1.2
+xref: EC:5.6.1.4
+xref: MetaCyc:3.6.4.2-RXN
+xref: MetaCyc:3.6.4.5-RXN
is_a: GO:0003777 ! microtubule motor activity
+property_value: skos:narrowMatch EC:5.6.1.2
+property_value: skos:narrowMatch EC:5.6.1.4
+property_value: skos:narrowMatch MetaCyc:3.6.4.2-RXN
+property_value: skos:narrowMatch MetaCyc:3.6.4.5-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18664" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21289" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25828" xsd:anyURI
@@ -84891,7 +88154,6 @@
synonym: "myosin ATPase activity" EXACT []
is_obsolete: true
replaced_by: GO:0000146
-consider: GO:0030048
[Term]
id: GO:0008571
@@ -84901,8 +88163,7 @@
comment: This term was made obsolete because it represents a class of gene products.
synonym: "non-chaperonin molecular chaperone ATPase activity" EXACT []
is_obsolete: true
-replaced_by: GO:0016887
-consider: GO:0006457
+replaced_by: GO:0044183
[Term]
id: GO:0008572
@@ -84923,7 +88184,6 @@
synonym: "peroxisome-assembly ATPase activity" EXACT []
is_obsolete: true
replaced_by: GO:0016887
-consider: GO:0007031
[Term]
id: GO:0008574
@@ -84940,7 +88200,9 @@
xref: EC:5.6.1.3
xref: MetaCyc:3.6.4.4-RXN
is_a: GO:0003777 ! microtubule motor activity
+property_value: skos:exactMatch EC:5.6.1.3
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18664" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008575
@@ -84960,9 +88222,7 @@
comment: This term was made obsolete because it incorporates process information.
synonym: "vesicle-fusing ATPase activity" EXACT []
is_obsolete: true
-replaced_by: GO:0016887
-consider: GO:0016192
-consider: GO:0061025
+replaced_by: GO:0140657
[Term]
id: GO:0008579
@@ -85219,6 +88479,9 @@
xref: Reactome:R-HSA-390427 "1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate"
xref: RHEA:36171
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.26
+property_value: skos:exactMatch RHEA:36171
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008610
@@ -85554,7 +88817,6 @@
name: rRNA methyltransferase activity
namespace: molecular_function
def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule." [GOC:mah]
-xref: Reactome:R-HSA-9911509 "RMTases methylate 16S ribosomal RNA"
is_a: GO:0008173 ! RNA methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
is_a: GO:0140102 ! catalytic activity, acting on a rRNA
@@ -85569,6 +88831,7 @@
xref: RHEA:54152
is_a: GO:0016436 ! rRNA (uridine) methyltransferase activity
is_a: GO:0062105 ! RNA 2'-O-methyltransferase activity
+property_value: skos:exactMatch RHEA:54152
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29545" xsd:anyURI
@@ -85618,9 +88881,13 @@
synonym: "phospholipid biosynthesis" EXACT []
synonym: "phospholipid formation" EXACT []
synonym: "phospholipid synthesis" EXACT []
+xref: MetaCyc:PHOSLIPSYN-PWY
+xref: MetaCyc:PHOSLIPSYN2-PWY
is_a: GO:0006644 ! phospholipid metabolic process
is_a: GO:0008610 ! lipid biosynthetic process
is_a: GO:0090407 ! organophosphate biosynthetic process
+property_value: skos:narrowMatch MetaCyc:PHOSLIPSYN-PWY
+property_value: skos:narrowMatch MetaCyc:PHOSLIPSYN2-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20092" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -85663,7 +88930,6 @@
namespace: molecular_function
def: "Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:ai]
subset: goslim_metagenomics
-is_a: GO:0033218 ! amide binding
is_a: GO:0033293 ! monocarboxylic acid binding
is_a: GO:1901363 ! heterocyclic compound binding
is_a: GO:1901681 ! sulfur compound binding
@@ -85697,6 +88963,9 @@
xref: RHEA:16933
xref: UM-BBD_reactionID:r0357
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.99.7
+property_value: skos:exactMatch RHEA:16933
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008661
@@ -85713,6 +88982,9 @@
xref: MetaCyc:DXS-RXN
xref: RHEA:12605
is_a: GO:0016744 ! transketolase or transaldolase activity
+property_value: skos:exactMatch EC:2.2.1.7
+property_value: skos:exactMatch RHEA:12605
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008662
@@ -85729,6 +89001,9 @@
xref: MetaCyc:1PFRUCTPHOSN-RXN
xref: RHEA:14213
is_a: GO:0008443 ! phosphofructokinase activity
+property_value: skos:exactMatch EC:2.7.1.56
+property_value: skos:exactMatch RHEA:14213
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008663
@@ -85751,6 +89026,9 @@
xref: MetaCyc:CYCPHOSDIESTER-RXN
xref: RHEA:19621
is_a: GO:0004112 ! cyclic-nucleotide phosphodiesterase activity
+property_value: skos:exactMatch EC:3.1.4.16
+property_value: skos:exactMatch RHEA:19621
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008664
@@ -85761,7 +89039,10 @@
xref: EC:3.1.4.58
xref: RHEA:11828
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.58
+property_value: skos:exactMatch RHEA:11828
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27437" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008666
@@ -85781,6 +89062,9 @@
xref: MetaCyc:TETHYDPICSUCC-RXN
xref: RHEA:17325
is_a: GO:0016749 ! N-succinyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.117
+property_value: skos:exactMatch RHEA:17325
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008667
@@ -85794,10 +89078,13 @@
xref: MetaCyc:DHBDEHYD-RXN
xref: RHEA:23824
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.28
+property_value: skos:exactMatch RHEA:23824
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008668
-name: 2,3-dihydroxybenzoate--[aryl-carrier protein] ligase
+name: 2,3-dihydroxybenzoate--[aryl-carrier protein] ligase activity
namespace: molecular_function
def: "Catalysis of the reaction: 2,3-dihydroxybenzoate + ATP + holo-[ACP] = 2,3-dihydroxybenzoyl-[ACP] + AMP + diphosphate." [RHEA:61652]
synonym: "(2,3-dihydroxybenzoyl)adenylate synthase activity" NARROW []
@@ -85807,8 +89094,11 @@
xref: MetaCyc:RXN-19445
xref: RHEA:61652
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.71
+property_value: skos:exactMatch RHEA:61652
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27539" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008670
@@ -85821,7 +89111,16 @@
synonym: "4-enoyl-CoA reductase activity" RELATED [EC:1.3.1.34]
synonym: "trans-2,3-didehydroacyl-CoA:NADP+ 4-oxidoreductase activity" RELATED [EC:1.3.1.34]
xref: EC:1.3.1.34
+xref: MetaCyc:RXN-20994
+xref: MetaCyc:RXN-20995
+xref: RHEA:12136
+xref: RHEA:45232
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.34
+property_value: skos:narrowMatch MetaCyc:RXN-20994
+property_value: skos:narrowMatch MetaCyc:RXN-20995
+property_value: skos:narrowMatch RHEA:12136
+property_value: skos:narrowMatch RHEA:45232
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -85840,6 +89139,9 @@
xref: RHEA:16525
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.58
+property_value: skos:exactMatch RHEA:16525
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008672
@@ -85854,7 +89156,10 @@
xref: MetaCyc:4.1.2.20-RXN
xref: RHEA:10268
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.20
+property_value: skos:exactMatch RHEA:10268
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008673
@@ -85875,6 +89180,9 @@
xref: RHEA:14797
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.45
+property_value: skos:exactMatch RHEA:14797
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008674
@@ -85897,6 +89205,9 @@
xref: MetaCyc:DEHYDDEOXPHOSGALACT-ALDOL-RXN
xref: RHEA:24464
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.21
+property_value: skos:exactMatch RHEA:24464
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008675
@@ -85921,6 +89232,9 @@
xref: MetaCyc:KDPGALDOL-RXN
xref: RHEA:17089
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.14
+property_value: skos:exactMatch RHEA:17089
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008676
@@ -85945,6 +89259,9 @@
xref: MetaCyc:KDO-8PSYNTH-RXN
xref: RHEA:14053
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.55
+property_value: skos:exactMatch RHEA:14053
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008677
@@ -85963,6 +89280,9 @@
xref: MetaCyc:2-DEHYDROPANTOATE-REDUCT-RXN
xref: RHEA:16233
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.169
+property_value: skos:exactMatch RHEA:16233
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008678
@@ -85976,6 +89296,9 @@
xref: MetaCyc:KDUD-RXN
xref: RHEA:12160
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.125
+property_value: skos:exactMatch RHEA:12160
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008679
@@ -85986,8 +89309,14 @@
synonym: "tartronate semialdehyde reductase (NADPH) activity" RELATED [EC:1.1.1.60]
xref: EC:1.1.1.60
xref: MetaCyc:TSA-REDUCT-RXN
+xref: RHEA:18841
+xref: RHEA:18845
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.60
+property_value: skos:narrowMatch RHEA:18841
+property_value: skos:narrowMatch RHEA:18845
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25302" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008681
@@ -85997,7 +89326,9 @@
xref: MetaCyc:2-OCTAPRENYL-6-METHOXYPHENOL-HYDROX-RXN
xref: RHEA:29407
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:29407
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27952" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008682
@@ -86008,10 +89339,15 @@
synonym: "demethoxy-ubiquinone hydroxylase" RELATED [GOC:vw]
synonym: "demethoxyubiquinone monooxygenase" RELATED [GOC:vw]
xref: EC:1.14.99.60
+xref: MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN
xref: MetaCyc:RXN-18458
xref: RHEA:50908
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.60
+property_value: skos:exactMatch MetaCyc:RXN-18458
+property_value: skos:exactMatch RHEA:50908
+property_value: skos:narrowMatch MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/11259" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27862" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28053" xsd:anyURI
@@ -86032,6 +89368,9 @@
xref: MetaCyc:RXN-7774
xref: RHEA:10524
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.71
+property_value: skos:exactMatch RHEA:10524
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008684
@@ -86049,6 +89388,9 @@
xref: RHEA:22580
xref: UM-BBD_enzymeID:r0101
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.80
+property_value: skos:exactMatch RHEA:22580
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008685
@@ -86064,6 +89406,9 @@
xref: MetaCyc:RXN0-302
xref: RHEA:23864
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
+property_value: skos:exactMatch EC:4.6.1.12
+property_value: skos:exactMatch RHEA:23864
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008686
@@ -86075,6 +89420,9 @@
xref: MetaCyc:DIOHBUTANONEPSYN-RXN
xref: RHEA:18457
is_a: GO:0016830 ! carbon-carbon lyase activity
+property_value: skos:exactMatch EC:4.1.99.12
+property_value: skos:exactMatch RHEA:18457
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008687
@@ -86091,6 +89439,9 @@
xref: RHEA:15633
xref: UM-BBD_reactionID:r0364
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.15
+property_value: skos:exactMatch RHEA:15633
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008688
@@ -86102,6 +89453,9 @@
xref: MetaCyc:MHPHYDROXY-RXN
xref: RHEA:24785
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.127
+property_value: skos:exactMatch RHEA:24785
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008689
@@ -86133,6 +89487,9 @@
xref: MetaCyc:CPM-KDOSYNTH-RXN
xref: RHEA:23448
is_a: GO:0070567 ! cytidylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.38
+property_value: skos:exactMatch RHEA:23448
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008691
@@ -86150,6 +89507,9 @@
xref: MetaCyc:3-HYDROXYBUTYRYL-COA-DEHYDROGENASE-RXN
xref: RHEA:16197
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.157
+property_value: skos:exactMatch RHEA:16197
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008692
@@ -86163,6 +89523,9 @@
xref: MetaCyc:OHBUTYRYL-COA-EPIM-RXN
xref: RHEA:21760
is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives
+property_value: skos:exactMatch EC:5.1.2.3
+property_value: skos:exactMatch RHEA:21760
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008693
@@ -86203,7 +89566,10 @@
xref: MetaCyc:RXN-15309
xref: RHEA:41680
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.98
+property_value: skos:exactMatch RHEA:41680
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30159" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008695
@@ -86219,7 +89585,10 @@
xref: RHEA:20357
xref: UM-BBD_enzymeID:e0307
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.19
+property_value: skos:exactMatch RHEA:20357
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008696
@@ -86240,6 +89609,9 @@
xref: MetaCyc:ADCLY-RXN
xref: RHEA:16201
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.38
+property_value: skos:exactMatch RHEA:16201
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008697
@@ -86254,6 +89626,9 @@
xref: MetaCyc:5.3.1.17-RXN
xref: RHEA:23896
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.17
+property_value: skos:exactMatch RHEA:23896
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008700
@@ -86274,9 +89649,13 @@
synonym: "hydroxyketoglutaric aldolase activity" RELATED [EC:4.1.3.16]
synonym: "KHG-aldolase activity" RELATED [EC:4.1.3.16]
xref: EC:4.1.3.16
+xref: MetaCyc:4OH2OXOGLUTARALDOL-RXN
xref: Reactome:R-HSA-6784423 "HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate"
xref: RHEA:18169
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.16
+property_value: skos:exactMatch RHEA:18169
+property_value: skos:narrowMatch MetaCyc:4OH2OXOGLUTARALDOL-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28306" xsd:anyURI
[Term]
@@ -86297,6 +89676,9 @@
xref: RHEA:22624
xref: UM-BBD_enzymeID:r0100
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.39
+property_value: skos:exactMatch RHEA:22624
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008703
@@ -86311,6 +89693,9 @@
xref: MetaCyc:RIBOFLAVINSYNREDUC-RXN
xref: RHEA:17845
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.193
+property_value: skos:exactMatch RHEA:17845
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008704
@@ -86331,6 +89716,9 @@
xref: RHEA:18813
xref: UM-BBD_reactionID:r0366
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.10
+property_value: skos:exactMatch RHEA:18813
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008705
@@ -86343,7 +89731,7 @@
synonym: "5-methyltetrahydrofolate:L-homocysteine S-methyltransferase activity" RELATED [EC:2.1.1.13]
synonym: "B12 N(5)-methyltetrahydrofolate homocysteine methyltransferase activity" RELATED [EC:2.1.1.13]
synonym: "B12 N5-methyltetrahydrofolate homocysteine methyltransferase activity" RELATED [EC:2.1.1.13]
-synonym: "cobalamin-dependent methionine synthase activity" RELATED [EC:2.1.1.13]
+synonym: "cobalamin-dependent methionine synthase activity" EXACT [EC:2.1.1.13]
synonym: "MetH" RELATED [EC:2.1.1.13]
synonym: "methionine synthase (cobalamin-dependent) activity" RELATED [EC:2.1.1.13]
synonym: "methyltetrahydrofolate--homocysteine vitamin B12 methyltransferase activity" RELATED [EC:2.1.1.13]
@@ -86365,9 +89753,12 @@
xref: Reactome:R-HSA-3149539 "MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin"
xref: RHEA:11172
is_a: GO:0008172 ! S-methyltransferase activity
-is_a: GO:0042084 ! 5-methyltetrahydrofolate-dependent methyltransferase activity
relationship: part_of GO:0071267 ! L-methionine salvage
+property_value: skos:exactMatch EC:2.1.1.13
+property_value: skos:exactMatch RHEA:11172
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30110" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30968" xsd:anyURI
[Term]
id: GO:0008706
@@ -86382,6 +89773,9 @@
xref: MetaCyc:6-PHOSPHO-BETA-GLUCOSIDASE-RXN
xref: RHEA:10772
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.86
+property_value: skos:exactMatch RHEA:10772
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008707
@@ -86398,6 +89792,9 @@
xref: MetaCyc:RXN-7241
xref: RHEA:20960
is_a: GO:0004446 ! inositol hexakisphosphate phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.62
+property_value: skos:exactMatch EC:3.1.3.26
+property_value: skos:exactMatch RHEA:20960
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25949" xsd:anyURI
[Term]
@@ -86415,6 +89812,9 @@
xref: MetaCyc:7-ALPHA-HYDROXYSTEROID-DEH-RXN
xref: RHEA:19409
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.159
+property_value: skos:exactMatch RHEA:19409
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008710
@@ -86434,6 +89834,9 @@
xref: MetaCyc:7KAPSYN-RXN
xref: RHEA:20712
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.47
+property_value: skos:exactMatch RHEA:20712
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008711
@@ -86458,6 +89861,9 @@
xref: MetaCyc:5.1.3.20-RXN
xref: RHEA:17577
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.20
+property_value: skos:exactMatch RHEA:17577
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008713
@@ -86469,6 +89875,9 @@
xref: MetaCyc:RXN-22477
xref: RHEA:74071
is_a: GO:0008920 ! lipopolysaccharide heptosyltransferase activity
+property_value: skos:exactMatch EC:2.4.99.24
+property_value: skos:exactMatch MetaCyc:RXN-22477
+property_value: skos:exactMatch RHEA:74071
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -86484,6 +89893,9 @@
xref: MetaCyc:AMP-NUCLEOSID-RXN
xref: RHEA:20129
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.2.4
+property_value: skos:exactMatch RHEA:20129
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008715
@@ -86499,6 +89911,9 @@
xref: MetaCyc:CDPDIGLYPYPHOSPHA-RXN
xref: RHEA:15221
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.26
+property_value: skos:exactMatch RHEA:15221
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008716
@@ -86516,6 +89931,9 @@
xref: MetaCyc:DALADALALIG-RXN
xref: RHEA:11224
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.4
+property_value: skos:exactMatch RHEA:11224
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008717
@@ -86536,8 +89954,13 @@
def: "Catalysis of the reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor." [RHEA:18125]
synonym: "D-amino-acid:(acceptor) oxidoreductase (deaminating)" EXACT []
synonym: "D-amino-acid:acceptor oxidoreductase (deaminating)" EXACT []
+xref: EC:1.4.5.1
+xref: MetaCyc:RXN-11193
xref: RHEA:18125
is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors
+property_value: skos:exactMatch RHEA:18125
+property_value: skos:narrowMatch EC:1.4.5.1
+property_value: skos:narrowMatch MetaCyc:RXN-11193
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -86550,7 +89973,10 @@
xref: MetaCyc:H2NTPEPIM-RXN
xref: RHEA:28346
is_a: GO:0016854 ! racemase and epimerase activity
+property_value: skos:exactMatch EC:5.1.99.7
+property_value: skos:exactMatch RHEA:28346
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29695" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008720
@@ -86566,7 +89992,10 @@
xref: RHEA:16369
is_a: GO:0047809 ! D-lactate dehydrogenase activity
is_a: GO:0140175 ! (2R)-2-hydroxyacid dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.28
+property_value: skos:exactMatch RHEA:16369
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30132" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008721
@@ -86589,6 +90018,9 @@
xref: Reactome:R-HSA-9034539 "PXLP-K56-SRR dimer deaminates L-Ser"
xref: RHEA:13977
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.18
+property_value: skos:exactMatch RHEA:13977
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008724
@@ -86613,6 +90045,9 @@
xref: EC:3.2.2.20
xref: MetaCyc:RXN0-5189
is_a: GO:0043733 ! DNA-3-methylbase glycosylase activity
+property_value: skos:broadMatch EC:3.2.2.21
+property_value: skos:exactMatch EC:3.2.2.20
+property_value: skos:exactMatch MetaCyc:RXN0-5189
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
@@ -86632,6 +90067,9 @@
xref: MetaCyc:RXN0-280
xref: RHEA:23064
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.5
+property_value: skos:exactMatch RHEA:23064
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008727
@@ -86641,6 +90079,8 @@
xref: MetaCyc:GDPMANMANHYDRO-RXN
xref: RHEA:28102
is_a: GO:0015923 ! mannosidase activity
+property_value: skos:exactMatch RHEA:28102
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008728
@@ -86663,6 +90103,9 @@
xref: MetaCyc:GTPPYPHOSKIN-RXN
xref: RHEA:22088
is_a: GO:0016778 ! diphosphotransferase activity
+property_value: skos:exactMatch EC:2.7.6.5
+property_value: skos:exactMatch RHEA:22088
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008730
@@ -86680,6 +90123,9 @@
xref: MetaCyc:LTARTDEHYDRA-RXN
xref: RHEA:15413
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.32
+property_value: skos:exactMatch RHEA:15413
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008732
@@ -86692,6 +90138,9 @@
xref: MetaCyc:LTAA-RXN
xref: RHEA:26209
is_a: GO:0004793 ! threonine aldolase activity
+property_value: skos:exactMatch EC:4.1.2.49
+property_value: skos:exactMatch RHEA:26209
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008733
@@ -86705,6 +90154,9 @@
xref: MetaCyc:ARABISOM-RXN
xref: RHEA:14821
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.4
+property_value: skos:exactMatch RHEA:14821
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008734
@@ -86713,20 +90165,36 @@
def: "Catalysis of the reaction: L-aspartate + O2 = iminosuccinate + H2O2. Can also use fumatate as electron acceptor under anaerobic conditions, yielding succinate." [EC:1.4.3.16]
synonym: "L-aspartate:oxygen oxidoreductase" RELATED [EC:1.4.3.16]
xref: EC:1.4.3.16
+xref: MetaCyc:L-ASPARTATE-OXID-RXN
+xref: MetaCyc:RXN-9772
+xref: RHEA:25876
+xref: RHEA:30043
is_a: GO:0001716 ! L-amino-acid oxidase activity
+property_value: skos:exactMatch EC:1.4.3.16
+property_value: skos:narrowMatch MetaCyc:L-ASPARTATE-OXID-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-9772
+property_value: skos:narrowMatch RHEA:25876
+property_value: skos:narrowMatch RHEA:30043
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
id: GO:0008735
name: L-carnitine CoA-transferase activity
namespace: molecular_function
-def: "Catalysis of the reactions: (E)-4-(trimethylammonio)but-2-enoyl-CoA + L-carnitine = (E)-4-(trimethylammonio)but-2-enoate + L-carnitinyl-CoA and 4-trimethylammoniobutanoyl-CoA + L-carnitine = 4-trimethylammoniobutanoate + L-carnitinyl-CoA." [PMID:7815937, PMID:8188598]
+def: "Catalysis of the reactions: (E)-4-(trimethylammonio)but-2-enoyl-CoA + L-carnitine = (E)-4-(trimethylammonio)but-2-enoate + L-carnitinyl-CoA and 4-trimethylammoniobutanoyl-CoA + L-carnitine = 4-trimethylammoniobutanoate + L-carnitinyl-CoA." [EC:2.8.3.21, PMID:7815937, PMID:8188598]
synonym: "L-carnitine dehydratase activity" EXACT []
synonym: "L-carnitine hydro-lyase [4-(trimethylammonio)but-2-enoate-forming]" RELATED []
synonym: "L-carnitine hydro-lyase activity" RELATED []
+xref: EC:2.8.3.21
+xref: RHEA:28338
+xref: RHEA:28526
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.21
+property_value: skos:narrowMatch RHEA:28338
+property_value: skos:narrowMatch RHEA:28526
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23098" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23472" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0008736
@@ -86739,6 +90207,9 @@
xref: MetaCyc:FUCISOM-RXN
xref: RHEA:17233
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.25
+property_value: skos:exactMatch RHEA:17233
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008737
@@ -86754,6 +90225,9 @@
xref: RHEA:12376
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.51
+property_value: skos:exactMatch RHEA:12376
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008738
@@ -86769,6 +90243,9 @@
xref: MetaCyc:FUCPALDOL-RXN
xref: RHEA:12933
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.17
+property_value: skos:exactMatch RHEA:12933
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008740
@@ -86783,6 +90260,9 @@
xref: MetaCyc:RHAMNISOM-RXN
xref: RHEA:23160
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.14
+property_value: skos:exactMatch RHEA:23160
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008741
@@ -86797,6 +90277,9 @@
xref: RHEA:22072
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.16
+property_value: skos:exactMatch RHEA:22072
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008742
@@ -86815,12 +90298,15 @@
xref: MetaCyc:RIBULPEPIM-RXN
xref: RHEA:22368
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.4
+property_value: skos:exactMatch RHEA:22368
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008743
name: L-threonine 3-dehydrogenase activity
namespace: molecular_function
-def: "Catalysis of the reaction: L-threonine + NAD+ = L-2-amino-3-oxobutanoate + CO2 + NADH." [EC:1.1.1.103, RHEA:13161]
+def: "Catalysis of the reaction: L-threonine + NAD+ = (2S)-2-amino-3-oxobutanoate + NADH + H+." [RHEA:13161]
synonym: "L-threonine dehydrogenase activity" RELATED [EC:1.1.1.103]
synonym: "L-threonine:NAD+ oxidoreductase activity" RELATED [EC:1.1.1.103]
synonym: "threonine 3-dehydrogenase activity" BROAD []
@@ -86828,8 +90314,13 @@
xref: EC:1.1.1.103
xref: KEGG_REACTION:R01465
xref: MetaCyc:THREODEHYD-RXN
+xref: Reactome:R-HSA-6798667 "TDH tetramer oxidises L-Thr to 2A-3OB"
xref: RHEA:13161
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.103
+property_value: skos:exactMatch RHEA:13161
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31059" xsd:anyURI
[Term]
id: GO:0008744
@@ -86843,7 +90334,10 @@
xref: MetaCyc:LYXK-RXN
xref: RHEA:18869
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.53
+property_value: skos:exactMatch RHEA:18869
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26853" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008745
@@ -86864,6 +90358,8 @@
xref: Reactome:R-HSA-6799977 "PGLYRP2 hydrolyzes bacterial peptidoglycan"
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0061783 ! peptidoglycan muralytic activity
+property_value: skos:exactMatch EC:3.5.1.28
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008746
@@ -86905,6 +90401,9 @@
xref: Reactome:R-HSA-4085217 "NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate"
xref: RHEA:23296
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.3
+property_value: skos:exactMatch RHEA:23296
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008748
@@ -86914,6 +90413,8 @@
xref: MetaCyc:RXN0-5101
xref: RHEA:35523
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:35523
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008750
@@ -86926,7 +90427,10 @@
is_a: GO:0015078 ! proton transmembrane transporter activity
is_a: GO:0015453 ! oxidoreduction-driven active transmembrane transporter activity
is_a: GO:0022853 ! active monoatomic ion transmembrane transporter activity
+property_value: skos:exactMatch EC:7.1.1.1
+property_value: skos:exactMatch RHEA:47992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27814" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008751
@@ -86949,7 +90453,9 @@
synonym: "NAD(P)H-dependent FMN reductase activity" RELATED []
xref: EC:1.5.1.39
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.39
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/12432" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008753
@@ -86961,10 +90467,16 @@
synonym: "reduced nicotinamide adenine dinucleotide phosphate (quinone) dehydrogenase" RELATED [EC:1.6.5.10]
xref: EC:1.6.5.10
xref: KEGG_REACTION:R07359
+xref: MetaCyc:RXN0-271
xref: MetaCyc:RXN0-7385
xref: RHEA:46164
is_a: GO:0003955 ! NAD(P)H dehydrogenase (quinone) activity
is_a: GO:0003959 ! NADPH dehydrogenase activity
+property_value: skos:exactMatch EC:1.6.5.10
+property_value: skos:exactMatch KEGG_REACTION:R07359
+property_value: skos:exactMatch MetaCyc:RXN0-7385
+property_value: skos:exactMatch RHEA:46164
+property_value: skos:narrowMatch MetaCyc:RXN0-271
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -86975,7 +90487,9 @@
xref: EC:2.4.99.26
xref: MetaCyc:RXN-13611
is_a: GO:0016757 ! glycosyltransferase activity
+property_value: skos:exactMatch EC:2.4.99.26
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29595" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008755
@@ -87001,6 +90515,9 @@
xref: RHEA:17009
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.26
+property_value: skos:exactMatch RHEA:17009
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008757
@@ -87019,6 +90536,8 @@
xref: MetaCyc:LIPIDXSYNTHESIS-RXN
xref: RHEA:25213
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch RHEA:25213
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008759
@@ -87054,6 +90573,9 @@
xref: MetaCyc:UDPNACETYLGLUCOSAMENOLPYRTRANS-RXN
xref: RHEA:18681
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.7
+property_value: skos:exactMatch RHEA:18681
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008761
@@ -87072,6 +90594,9 @@
xref: Reactome:R-HSA-4088338 "Defective GNE does not hydrolyse UDP-GlcNAc"
xref: RHEA:17213
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.14
+property_value: skos:exactMatch RHEA:17213
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008762
@@ -87090,6 +90615,9 @@
xref: MetaCyc:UDPNACETYLMURAMATEDEHYDROG-RXN
xref: RHEA:12248
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.98
+property_value: skos:exactMatch RHEA:12248
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008763
@@ -87116,6 +90644,9 @@
xref: MetaCyc:UDP-NACMUR-ALA-LIG-RXN
xref: RHEA:23372
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.8
+property_value: skos:exactMatch RHEA:23372
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008764
@@ -87134,6 +90665,9 @@
xref: MetaCyc:UDP-NACMURALA-GLU-LIG-RXN
xref: RHEA:16429
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.9
+property_value: skos:exactMatch RHEA:16429
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008765
@@ -87150,6 +90684,9 @@
xref: MetaCyc:UDP-NACMURALGLDAPLIG-RXN
xref: RHEA:23676
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.13
+property_value: skos:exactMatch RHEA:23676
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008766
@@ -87159,6 +90696,8 @@
xref: MetaCyc:UDP-NACMURALGLDAPAALIG-RXN
xref: RHEA:28374
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:broadMatch EC:6.3.2.10
+property_value: skos:exactMatch RHEA:28374
[Term]
id: GO:0008767
@@ -87171,6 +90710,9 @@
xref: MetaCyc:GALPMUT-RXN
xref: RHEA:24132
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.9
+property_value: skos:exactMatch RHEA:24132
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008768
@@ -87186,6 +90728,8 @@
xref: MetaCyc:UDPSUGARHYDRO-RXN
xref: Reactome:R-HSA-6810464 "NUDT14 hydrolyses UDP-Glc to G1P and UMP"
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.45
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008769
@@ -87222,6 +90766,9 @@
xref: RHEA:20537
is_a: GO:0008081 ! phosphoric diester hydrolase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:3.1.4.14
+property_value: skos:exactMatch RHEA:20537
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008771
@@ -87239,6 +90786,9 @@
xref: MetaCyc:CITC-RXN
xref: RHEA:23788
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.22
+property_value: skos:exactMatch RHEA:23788
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008772
@@ -87260,6 +90810,9 @@
xref: MetaCyc:PHOSICITDEHASE-RXN
xref: RHEA:43540
is_a: GO:0106310 ! protein serine kinase activity
+property_value: skos:exactMatch EC:2.7.11.5
+property_value: skos:exactMatch RHEA:43540
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0008773
@@ -87277,6 +90830,9 @@
xref: RHEA:13673
is_a: GO:0070569 ! uridylyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.7.7.59
+property_value: skos:exactMatch RHEA:13673
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008774
@@ -87292,6 +90848,9 @@
xref: MetaCyc:ACETALD-DEHYDROG-RXN
xref: RHEA:23288
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.10
+property_value: skos:exactMatch RHEA:23288
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008775
@@ -87310,6 +90869,9 @@
xref: RHEA:13381
xref: UM-BBD_enzymeID:r0012
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.8
+property_value: skos:exactMatch RHEA:13381
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008776
@@ -87327,6 +90889,9 @@
xref: RHEA:11352
is_a: GO:0016301 ! kinase activity
is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor
+property_value: skos:exactMatch EC:2.7.2.1
+property_value: skos:exactMatch RHEA:11352
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008777
@@ -87342,6 +90907,9 @@
xref: RHEA:15941
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0019213 ! deacetylase activity
+property_value: skos:exactMatch EC:3.5.1.16
+property_value: skos:exactMatch RHEA:15941
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008779
@@ -87356,6 +90924,9 @@
xref: MetaCyc:ACYLGPEACYLTRANS-RXN
xref: RHEA:10304
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.40
+property_value: skos:exactMatch RHEA:10304
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008780
@@ -87372,7 +90943,10 @@
xref: MetaCyc:RXN-22480
xref: RHEA:67812
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.129
+property_value: skos:exactMatch RHEA:67812
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30177" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008781
@@ -87408,6 +90982,9 @@
xref: Reactome:R-HSA-4084982 "CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac"
xref: RHEA:11344
is_a: GO:0070567 ! cytidylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.43
+property_value: skos:exactMatch RHEA:11344
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008782
@@ -87424,6 +91001,9 @@
xref: MetaCyc:ADENOSYLHOMOCYSTEINE-NUCLEOSIDASE-RXN
xref: RHEA:17805
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.2.9
+property_value: skos:exactMatch RHEA:17805
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008783
@@ -87439,6 +91019,9 @@
xref: Reactome:R-HSA-350604 "Agmatine + H2O <=> putrescine + urea"
xref: RHEA:13929
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.11
+property_value: skos:exactMatch RHEA:13929
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008784
@@ -87451,6 +91034,9 @@
xref: MetaCyc:ALARACECAT-RXN
xref: RHEA:20249
is_a: GO:0047661 ! amino-acid racemase activity
+property_value: skos:exactMatch EC:5.1.1.1
+property_value: skos:exactMatch RHEA:20249
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008785
@@ -87470,7 +91056,9 @@
xref: MetaCyc:RXN0-303
xref: RHEA:28430
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch RHEA:28430
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27059" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008787
@@ -87487,8 +91075,11 @@
xref: MetaCyc:ALLOSE-KINASE-RXN
xref: RHEA:14805
is_a: GO:0004396 ! hexokinase activity
+property_value: skos:exactMatch EC:2.7.1.55
+property_value: skos:exactMatch RHEA:14805
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26909" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27059" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008788
@@ -87502,6 +91093,9 @@
xref: MetaCyc:TRE6PHYDRO-RXN
xref: RHEA:23008
is_a: GO:0015927 ! trehalase activity
+property_value: skos:exactMatch EC:3.2.1.93
+property_value: skos:exactMatch RHEA:23008
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008789
@@ -87515,6 +91109,9 @@
xref: MetaCyc:ALTRODEHYDRAT-RXN
xref: RHEA:15957
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.7
+property_value: skos:exactMatch RHEA:15957
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008790
@@ -87529,6 +91126,9 @@
xref: MetaCyc:DARABISOM-RXN
xref: RHEA:13849
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.3
+property_value: skos:exactMatch RHEA:13849
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008791
@@ -87547,6 +91147,9 @@
xref: MetaCyc:ARGININE-N-SUCCINYLTRANSFERASE-RXN
xref: RHEA:15185
is_a: GO:0016749 ! N-succinyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.109
+property_value: skos:exactMatch RHEA:15185
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008792
@@ -87562,6 +91165,9 @@
xref: Reactome:R-HSA-350598 "Arginine<=>Agmatine+CO2"
xref: RHEA:17641
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.19
+property_value: skos:exactMatch RHEA:17641
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008793
@@ -87576,6 +91182,8 @@
xref: MetaCyc:2.6.1.57-RXN
xref: RHEA:17533
is_a: GO:0008483 ! transaminase activity
+property_value: skos:broadMatch EC:2.6.1.57
+property_value: skos:exactMatch RHEA:17533
[Term]
id: GO:0008794
@@ -87588,6 +91196,9 @@
xref: RHEA:22016
xref: UM-BBD_reactionID:r0635
is_a: GO:0030614 ! oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor
+property_value: skos:exactMatch EC:1.20.4.1
+property_value: skos:exactMatch RHEA:22016
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008795
@@ -87608,6 +91219,9 @@
xref: MetaCyc:NAD-SYNTH-NH3-RXN
xref: RHEA:21188
is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity
+property_value: skos:exactMatch EC:6.3.1.5
+property_value: skos:exactMatch RHEA:21188
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008796
@@ -87631,6 +91245,9 @@
xref: MetaCyc:ASPARTASE-RXN
xref: RHEA:16601
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.1
+property_value: skos:exactMatch RHEA:16601
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008798
@@ -87642,8 +91259,11 @@
xref: EC:3.4.19.5
xref: MetaCyc:3.4.19.5-RXN
xref: Reactome:R-HSA-5692495 "BACE1 cleaves APP(18-770) to APP(18-671) and APP(672-770)"
+xref: Reactome:R-HSA-5696365 "ASRGL1 hydrolyses aspartame to L-Asp, L-Phe"
is_a: GO:0008242 ! omega peptidase activity
is_a: GO:0070003 ! threonine-type peptidase activity
+property_value: skos:exactMatch EC:3.4.19.5
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008800
@@ -87663,13 +91283,11 @@
synonym: "penicillinase I, II" RELATED [EC:3.5.2.6]
xref: EC:3.5.2.6
xref: MetaCyc:BETA-LACTAMASE-RXN
-xref: Reactome:R-HSA-9911513 "BlaSHV-12 hydrolyzes ceftriaxone"
-xref: Reactome:R-HSA-9911515 "KPC-2 hydrolyzes cephalothin"
-xref: Reactome:R-HSA-9911518 "OXA-9 hydrolyzes penicillin G"
-xref: Reactome:R-HSA-9911519 "BlaSHV-12 hydrolyzes cephalothin"
-xref: Reactome:R-HSA-9911520 "TEM-1 hydrolyzes penicillin G"
xref: RHEA:20401
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.6
+property_value: skos:exactMatch RHEA:20401
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008801
@@ -87682,6 +91300,9 @@
xref: MetaCyc:BETA-PHOSPHOGLUCOMUTASE-RXN
xref: RHEA:20113
is_a: GO:0016868 ! intramolecular phosphotransferase activity
+property_value: skos:exactMatch EC:5.4.2.6
+property_value: skos:exactMatch RHEA:20113
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008802
@@ -87698,6 +91319,9 @@
xref: Reactome:R-HSA-6797955 "ALDH7A1 oxidises BETALD to BET"
xref: RHEA:15305
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.8
+property_value: skos:exactMatch RHEA:15305
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008803
@@ -87725,6 +91349,9 @@
xref: MetaCyc:3.6.1.41-RXN
xref: RHEA:24252
is_a: GO:0008796 ! bis(5'-nucleosyl)-tetraphosphatase activity
+property_value: skos:exactMatch EC:3.6.1.41
+property_value: skos:exactMatch RHEA:24252
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008804
@@ -87740,6 +91367,9 @@
xref: RHEA:10152
is_a: GO:0016301 ! kinase activity
is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor
+property_value: skos:exactMatch EC:2.7.2.2
+property_value: skos:exactMatch RHEA:10152
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008805
@@ -87761,6 +91391,9 @@
xref: UM-BBD_reactionID:r0650
xref: Wikipedia:Carbon-monoxide_dehydrogenase_(cytochrome_b-561)
is_a: GO:0016622 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.2.5.3
+property_value: skos:exactMatch RHEA:48880
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008806
@@ -87778,6 +91411,9 @@
xref: UM-BBD_enzymeID:r0110
xref: UM-BBD_enzymeID:r0286
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.45
+property_value: skos:exactMatch RHEA:12372
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008807
@@ -87791,6 +91427,9 @@
xref: MetaCyc:2.7.8.23-RXN
xref: RHEA:14045
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.23
+property_value: skos:exactMatch RHEA:14045
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008808
@@ -87805,6 +91444,8 @@
xref: MetaCyc:CARDIOLIPSYN-RXN
xref: RHEA:31451
is_a: GO:0030572 ! phosphatidyltransferase activity
+property_value: skos:exactMatch RHEA:31451
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008809
@@ -87839,6 +91480,8 @@
xref: EC:3.2.1.4
xref: MetaCyc:RXN-2043
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.4
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008811
@@ -87857,6 +91500,9 @@
xref: MetaCyc:CHLORAMPHENICOL-O-ACETYLTRANSFERASE-RXN
xref: RHEA:18421
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.28
+property_value: skos:exactMatch RHEA:18421
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008812
@@ -87874,6 +91520,9 @@
xref: Reactome:R-HSA-6797961 "CHDH oxidises Cho to BETALD"
xref: RHEA:17433
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.1
+property_value: skos:exactMatch RHEA:17433
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008813
@@ -87891,6 +91540,9 @@
xref: MetaCyc:CHORPYRLY-RXN
xref: RHEA:16505
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.40
+property_value: skos:exactMatch RHEA:16505
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008814
@@ -87902,6 +91554,9 @@
xref: MetaCyc:CITTRANS-RXN
xref: RHEA:19405
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.10
+property_value: skos:exactMatch RHEA:19405
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008815
@@ -87923,6 +91578,9 @@
xref: MetaCyc:CITLY-RXN
xref: RHEA:10760
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.6
+property_value: skos:exactMatch RHEA:10760
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008816
@@ -87935,6 +91593,9 @@
xref: MetaCyc:CITRYLY-RXN
xref: RHEA:20812
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.34
+property_value: skos:exactMatch RHEA:20812
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008817
@@ -87955,9 +91616,22 @@
synonym: "vitamin B12s adenosyltransferase activity" RELATED []
xref: EC:2.5.1.17
xref: KEGG_REACTION:R05218
+xref: MetaCyc:BTUR2-RXN
+xref: MetaCyc:RXN-19335
+xref: MetaCyc:RXN-19339
xref: Reactome:R-HSA-3159253 "MMAB adenosylates cob(I)alamin"
xref: Reactome:R-HSA-3322125 "Defective MMAB does not transfer adenosyl group from ATP to B12s"
+xref: RHEA:11528
+xref: RHEA:14725
+xref: RHEA:28671
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.17
+property_value: skos:narrowMatch MetaCyc:BTUR2-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-19335
+property_value: skos:narrowMatch MetaCyc:RXN-19339
+property_value: skos:narrowMatch RHEA:11528
+property_value: skos:narrowMatch RHEA:14725
+property_value: skos:narrowMatch RHEA:28671
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -87968,6 +91642,8 @@
xref: MetaCyc:COBALAMIN5PSYN-RXN
xref: RHEA:23560
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch RHEA:23560
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008819
@@ -87996,6 +91672,9 @@
xref: MetaCyc:COBINPGUANYLYLTRANS-RXN
xref: RHEA:22712
is_a: GO:0070568 ! guanylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.62
+property_value: skos:exactMatch RHEA:22712
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008821
@@ -88022,6 +91701,8 @@
xref: EC:3.1.21.10
xref: MetaCyc:3.1.22.4-RXN
is_a: GO:0016889 ! DNA endonuclease activity, producing 3'-phosphomonoesters
+property_value: skos:exactMatch EC:3.1.21.10
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008822
@@ -88042,12 +91723,14 @@
xref: MetaCyc:R170-RXN
xref: RHEA:66848
is_a: GO:0016723 ! oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:66848
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008824
name: cyanate hydratase activity
namespace: molecular_function
-def: "Catalysis of the reaction: cyanate + H2O = carbamate." [EC:4.2.1.104, RHEA:11120]
+def: "Catalysis of the reaction: cyanate + hydrogencarbonate + 3 H+ = NH4+ + 2 CO2." [RHEA:11120]
synonym: "carbamate hydro-lyase activity" RELATED [EC:4.2.1.104]
synonym: "cyanase activity" EXACT []
synonym: "cyanate aminohydrolase activity" RELATED [EC:4.2.1.104]
@@ -88058,7 +91741,11 @@
xref: MetaCyc:R524-RXN
xref: RHEA:11120
xref: UM-BBD_reactionID:r0608
-is_a: GO:0016840 ! carbon-nitrogen lyase activity
+is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.104
+property_value: skos:exactMatch RHEA:11120
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31104" xsd:anyURI
[Term]
id: GO:0008825
@@ -88074,8 +91761,17 @@
synonym: "unsaturated-phospholipid methyltransferase activity" BROAD [EC:2.1.1.79]
xref: EC:2.1.1.79
xref: MetaCyc:2.1.1.79-RXN
+xref: MetaCyc:RXN1G-2544
+xref: MetaCyc:RXN1G-3641
+xref: MetaCyc:RXN1G-45
xref: RHEA:11988
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.79
+property_value: skos:exactMatch MetaCyc:2.1.1.79-RXN
+property_value: skos:exactMatch RHEA:11988
+property_value: skos:narrowMatch MetaCyc:RXN1G-2544
+property_value: skos:narrowMatch MetaCyc:RXN1G-3641
+property_value: skos:narrowMatch MetaCyc:RXN1G-45
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -88087,6 +91783,8 @@
xref: MetaCyc:RXN0-279
xref: RHEA:28278
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch RHEA:28278
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008828
@@ -88104,8 +91802,11 @@
xref: MetaCyc:RXN0-384
xref: RHEA:28334
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:exactMatch EC:3.6.1.56
+property_value: skos:exactMatch RHEA:28334
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20656" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-10-18T13:22:38Z
@@ -88123,6 +91824,9 @@
xref: RHEA:22680
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.13
+property_value: skos:exactMatch RHEA:22680
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008830
@@ -88139,6 +91843,9 @@
xref: MetaCyc:DTDPDEHYDRHAMEPIM-RXN
xref: RHEA:16969
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.13
+property_value: skos:exactMatch RHEA:16969
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008831
@@ -88157,6 +91864,9 @@
xref: MetaCyc:DTDPDEHYRHAMREDUCT-RXN
xref: RHEA:21796
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.133
+property_value: skos:exactMatch RHEA:21796
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008832
@@ -88174,6 +91884,9 @@
xref: MetaCyc:DGTPTRIPHYDRO-RXN
xref: RHEA:15193
is_a: GO:0016793 ! triphosphoric monoester hydrolase activity
+property_value: skos:exactMatch EC:3.1.5.1
+property_value: skos:exactMatch RHEA:15193
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008833
@@ -88193,6 +91906,8 @@
xref: EC:3.1.21.2
xref: MetaCyc:RXN-20410
is_a: GO:0016888 ! DNA endonuclease activity, producing 5'-phosphomonoesters
+property_value: skos:exactMatch EC:3.1.21.2
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008834
@@ -88213,9 +91928,12 @@
xref: MetaCyc:RXN-8999
xref: RHEA:27551
is_a: GO:0045547 ! ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
+property_value: skos:exactMatch EC:2.5.1.31
+property_value: skos:exactMatch RHEA:27551
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26833" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008835
@@ -88229,9 +91947,15 @@
xref: EC:3.5.4.26
xref: KEGG_REACTION:R03459
xref: MetaCyc:RIBOFLAVINSYNDEAM-RXN
+xref: MetaCyc:RXN-10058
xref: RHEA:21868
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.26
+property_value: skos:exactMatch KEGG_REACTION:R03459
+property_value: skos:exactMatch MetaCyc:RIBOFLAVINSYNDEAM-RXN
+property_value: skos:exactMatch RHEA:21868
+property_value: skos:narrowMatch MetaCyc:RXN-10058
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25262" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -88251,6 +91975,9 @@
xref: MetaCyc:DIAMINOPIMDECARB-RXN
xref: RHEA:15101
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.20
+property_value: skos:exactMatch RHEA:15101
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008837
@@ -88263,6 +91990,9 @@
xref: MetaCyc:DIAMINOPIMEPIM-RXN
xref: RHEA:15393
is_a: GO:0047661 ! amino-acid racemase activity
+property_value: skos:exactMatch EC:5.1.1.7
+property_value: skos:exactMatch RHEA:15393
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008838
@@ -88275,12 +92005,18 @@
synonym: "diaminopropionatase activity" RELATED [EC:4.3.1.15]
xref: EC:4.3.1.15
xref: MetaCyc:4.3.1.15-RXN
+xref: RHEA:22084
+xref: RHEA:52432
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.15
+property_value: skos:narrowMatch RHEA:22084
+property_value: skos:narrowMatch RHEA:52432
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008839
-name: 4-hydroxy-tetrahydrodipicolinate reductase
+name: 4-hydroxy-tetrahydrodipicolinate reductase activity
namespace: molecular_function
def: "Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+." [EC:1.17.1.8]
synonym: "2,3,4,5-tetrahydrodipicolinate:NAD(P)+ oxidoreductase activity" RELATED [EC:1.17.1.8]
@@ -88288,14 +92024,19 @@
synonym: "dihydrodipicolinic acid reductase activity" RELATED [EC:1.17.1.8]
xref: EC:1.17.1.8
xref: MetaCyc:RXN-14014
+xref: RHEA:35323
+xref: RHEA:35331
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.17.1.8
+property_value: skos:narrowMatch RHEA:35323
+property_value: skos:narrowMatch RHEA:35331
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27695" xsd:anyURI
[Term]
id: GO:0008840
name: 4-hydroxy-tetrahydrodipicolinate synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: pyruvate + L-aspartate-4-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O." [PMID:8993314, RHEA:34171]
+def: "Catalysis of the reaction: L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O + H+." [PMID:8993314, RHEA:34171]
synonym: "DHDPS activity" RELATED [EC:4.3.3.7]
synonym: "dihydrodipicolinate synthase activity" EXACT []
synonym: "dihydrodipicolinate synthetase activity" RELATED [EC:4.3.3.7]
@@ -88306,7 +92047,11 @@
xref: KEGG_REACTION:R02292
xref: MetaCyc:DIHYDRODIPICSYN-RXN
xref: RHEA:34171
-is_a: GO:0016836 ! hydro-lyase activity
+is_a: GO:0016843 ! amine-lyase activity
+property_value: skos:exactMatch EC:4.3.3.7
+property_value: skos:exactMatch RHEA:34171
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31104" xsd:anyURI
[Term]
id: GO:0008841
@@ -88330,6 +92075,9 @@
xref: RHEA:23584
is_a: GO:0016881 ! acid-amino acid ligase activity
relationship: part_of GO:0006761 ! dihydrofolate biosynthetic process
+property_value: skos:exactMatch EC:6.3.2.12
+property_value: skos:exactMatch RHEA:23584
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008842
@@ -88352,7 +92100,9 @@
xref: EC:3.2.1.14
xref: MetaCyc:3.2.1.14-RXN
is_a: GO:0004568 ! chitinase activity
+property_value: skos:exactMatch EC:3.2.1.14
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28722" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008845
@@ -88402,7 +92152,9 @@
xref: MetaCyc:3.1.27.6-RXN
is_a: GO:0004521 ! RNA endonuclease activity
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
+property_value: skos:exactMatch EC:4.6.1.21
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008848
@@ -88424,9 +92176,10 @@
def: "Catalysis of the reaction: enterobactin + 3 H2O = 3 N-23-dihydroxybenzoyl-L-serine + 3 H+." [MetaCyc:RXN0-1661, PMID:4565531]
synonym: "enterobactin esterase activity" EXACT []
xref: MetaCyc:RXN0-1661
-xref: Reactome:R-HSA-9911599 "Fes hydrolyses ferrienterobactin to DHBS"
xref: RHEA:28018
is_a: GO:0016788 ! hydrolase activity, acting on ester bonds
+property_value: skos:exactMatch RHEA:28018
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008851
@@ -88439,6 +92192,9 @@
xref: MetaCyc:ETHAMLY-RXN
xref: RHEA:15313
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.7
+property_value: skos:exactMatch RHEA:15313
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008852
@@ -88478,6 +92234,8 @@
xref: EC:3.1.11.5
xref: MetaCyc:RXN0-2605
is_a: GO:0016895 ! DNA exonuclease activity, producing 5'-phosphomonoesters
+property_value: skos:exactMatch EC:3.1.11.5
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008855
@@ -88492,6 +92250,8 @@
xref: EC:3.1.11.6
xref: MetaCyc:3.1.11.6-RXN
is_a: GO:0016895 ! DNA exonuclease activity, producing 5'-phosphomonoesters
+property_value: skos:exactMatch EC:3.1.11.6
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008856
@@ -88517,8 +92277,10 @@
xref: EC:3.1.13.1
xref: MetaCyc:3.1.13.1-RXN
is_a: GO:0000175 ! 3'-5'-RNA exonuclease activity
+property_value: skos:exactMatch EC:3.1.13.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27595" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28072" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008860
@@ -88541,7 +92303,10 @@
xref: MetaCyc:FERREDOXIN--NAD+-REDUCTASE-RXN
xref: RHEA:16521
is_a: GO:0008937 ! ferredoxin-[NAD(P)H] reductase activity
+property_value: skos:exactMatch EC:1.18.1.3
+property_value: skos:exactMatch RHEA:16521
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29598" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008861
@@ -88554,6 +92319,9 @@
xref: MetaCyc:PYRUVFORMLY-RXN
xref: RHEA:11844
is_a: GO:0016453 ! C-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.54
+property_value: skos:exactMatch RHEA:11844
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008863
@@ -88574,7 +92342,10 @@
xref: RHEA:15985
xref: UM-BBD_reactionID:r0103
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.17.1.9
+property_value: skos:exactMatch RHEA:15985
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008864
@@ -88589,6 +92360,9 @@
xref: MetaCyc:FORMYLTHFDEFORMYL-RXN
xref: RHEA:19833
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.10
+property_value: skos:exactMatch RHEA:19833
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008865
@@ -88603,6 +92377,9 @@
xref: MetaCyc:FRUCTOKINASE-RXN
xref: RHEA:16125
is_a: GO:0004396 ! hexokinase activity
+property_value: skos:exactMatch EC:2.7.1.4
+property_value: skos:exactMatch RHEA:16125
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008866
@@ -88620,6 +92397,9 @@
xref: MetaCyc:MANNONOXIDOREDUCT-RXN
xref: RHEA:15729
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.57
+property_value: skos:exactMatch RHEA:15729
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008867
@@ -88633,6 +92413,9 @@
xref: MetaCyc:GALACTARDEHYDRA-RXN
xref: RHEA:16005
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.42
+property_value: skos:exactMatch RHEA:16005
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008868
@@ -88644,6 +92427,9 @@
xref: MetaCyc:1.1.1.251-RXN
xref: RHEA:15137
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.251
+property_value: skos:exactMatch RHEA:15137
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008869
@@ -88659,6 +92445,9 @@
xref: MetaCyc:GALACTONDEHYDRAT-RXN
xref: RHEA:18649
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.6
+property_value: skos:exactMatch RHEA:18649
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008870
@@ -88673,6 +92462,9 @@
xref: MetaCyc:GALACTOACETYLTRAN-RXN
xref: RHEA:15713
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.18
+property_value: skos:exactMatch RHEA:15713
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008871
@@ -88687,6 +92479,8 @@
xref: EC:2.7.7.46
xref: MetaCyc:2.7.7.46-RXN
is_a: GO:0034068 ! aminoglycoside nucleotidyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.46
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008872
@@ -88700,6 +92494,9 @@
xref: MetaCyc:GLUCARDEHYDRA-RXN
xref: RHEA:14573
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.40
+property_value: skos:exactMatch RHEA:14573
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008873
@@ -88712,6 +92509,9 @@
xref: MetaCyc:1.1.1.215-RXN
xref: RHEA:16653
is_a: GO:0008875 ! gluconate dehydrogenase activity
+property_value: skos:exactMatch EC:1.1.1.215
+property_value: skos:exactMatch RHEA:16653
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008874
@@ -88726,6 +92526,8 @@
xref: EC:1.1.1.69
xref: MetaCyc:GLUCONATE-5-DEHYDROGENASE-RXN
is_a: GO:0008875 ! gluconate dehydrogenase activity
+property_value: skos:exactMatch EC:1.1.1.69
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008875
@@ -88751,6 +92553,8 @@
xref: RHEA:22152
is_a: GO:0004344 ! glucose dehydrogenase activity
is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.1.5.2
+property_value: skos:exactMatch RHEA:22152
[Term]
id: GO:0008877
@@ -88764,6 +92568,9 @@
xref: MetaCyc:GLUCOSE-1-PHOSPHAT-RXN
xref: RHEA:19933
is_a: GO:0050308 ! sugar-phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.10
+property_value: skos:exactMatch RHEA:19933
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008878
@@ -88788,6 +92595,9 @@
xref: MetaCyc:GLUC1PADENYLTRANS-RXN
xref: RHEA:12120
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.27
+property_value: skos:exactMatch RHEA:12120
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008879
@@ -88807,6 +92617,9 @@
xref: MetaCyc:DTDPGLUCOSEPP-RXN
xref: RHEA:15225
is_a: GO:0016779 ! nucleotidyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.24
+property_value: skos:exactMatch RHEA:15225
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008880
@@ -88821,7 +92634,12 @@
synonym: "uronic isomerase activity" RELATED [EC:5.3.1.12]
xref: EC:5.3.1.12
xref: MetaCyc:GLUCUROISOM-RXN
+xref: RHEA:13049
+xref: RHEA:27702
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.12
+property_value: skos:narrowMatch RHEA:13049
+property_value: skos:narrowMatch RHEA:27702
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
[Term]
@@ -88834,6 +92652,9 @@
xref: MetaCyc:GLUTRACE-RXN
xref: RHEA:12813
is_a: GO:0047661 ! amino-acid racemase activity
+property_value: skos:exactMatch EC:5.1.1.3
+property_value: skos:exactMatch RHEA:12813
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008882
@@ -88850,6 +92671,9 @@
xref: MetaCyc:GSADENYLATION-RXN
xref: RHEA:18589
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.42
+property_value: skos:exactMatch RHEA:18589
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008883
@@ -88863,6 +92687,9 @@
xref: RHEA:12344
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:1.2.1.70
+property_value: skos:exactMatch RHEA:12344
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008884
@@ -88876,6 +92703,9 @@
xref: MetaCyc:GSPAMID-RXN
xref: RHEA:17173
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.78
+property_value: skos:exactMatch RHEA:17173
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008885
@@ -88891,6 +92721,9 @@
xref: MetaCyc:GSPSYN-RXN
xref: RHEA:21272
is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity
+property_value: skos:exactMatch EC:6.3.1.8
+property_value: skos:exactMatch RHEA:21272
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008886
@@ -88912,7 +92745,10 @@
xref: MetaCyc:1.2.1.9-RXN
xref: RHEA:14669
is_a: GO:0120533 ! glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (non-phosphorylating) activity
+property_value: skos:exactMatch EC:1.2.1.9
+property_value: skos:exactMatch RHEA:14669
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28144" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008887
@@ -88934,6 +92770,9 @@
xref: RHEA:23516
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.31
+property_value: skos:exactMatch RHEA:23516
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008888
@@ -88947,7 +92786,10 @@
xref: MetaCyc:GLYCDEH-RXN
xref: RHEA:13769
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.6
+property_value: skos:exactMatch RHEA:13769
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008889
@@ -88964,6 +92806,9 @@
xref: Reactome:R-HSA-1483116 "GPCho is hydrolyzed to Cho and G3P by GPCPD1"
xref: RHEA:12969
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.46
+property_value: skos:exactMatch RHEA:12969
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008890
@@ -88976,6 +92821,9 @@
xref: MetaCyc:AKBLIG-RXN
xref: RHEA:20736
is_a: GO:0016453 ! C-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.29
+property_value: skos:exactMatch RHEA:20736
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008892
@@ -88992,6 +92840,9 @@
xref: RHEA:14665
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.3
+property_value: skos:exactMatch RHEA:14665
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008893
@@ -89009,7 +92860,12 @@
xref: EC:3.1.7.2
xref: MetaCyc:PPGPPSYN-RXN
xref: RHEA:14253
+xref: RHEA:33055
is_a: GO:0016794 ! diphosphoric monoester hydrolase activity
+property_value: skos:exactMatch EC:3.1.7.2
+property_value: skos:exactMatch RHEA:14253
+property_value: skos:narrowMatch RHEA:33055
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008894
@@ -89028,6 +92884,9 @@
xref: MetaCyc:PPPGPPHYDRO-RXN
xref: RHEA:13073
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.40
+property_value: skos:exactMatch RHEA:13073
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008897
@@ -89063,7 +92922,10 @@
xref: Reactome:R-HSA-199202 "Phosphopantetheine conjugation of the ACP domain of FAS"
xref: RHEA:12068
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.7
+property_value: skos:exactMatch RHEA:12068
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18113" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008898
@@ -89084,7 +92946,10 @@
xref: RHEA:21820
is_a: GO:0008172 ! S-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.10
+property_value: skos:exactMatch RHEA:21820
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25824" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008899
@@ -89099,6 +92964,9 @@
xref: MetaCyc:HOMSUCTRAN-RXN
xref: RHEA:22008
is_a: GO:0016750 ! O-succinyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.46
+property_value: skos:exactMatch RHEA:22008
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008900
@@ -89128,8 +92996,11 @@
xref: RHEA:22044
is_a: GO:0008553 ! P-type proton-exporting transporter activity
is_a: GO:0008556 ! P-type potassium transmembrane transporter activity
+property_value: skos:exactMatch EC:7.2.2.19
+property_value: skos:exactMatch RHEA:22044
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20821" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008901
@@ -89166,6 +93037,9 @@
xref: MetaCyc:HYDROG-RXN
xref: RHEA:17445
is_a: GO:0016699 ! oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.12.7.2
+property_value: skos:exactMatch RHEA:17445
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008902
@@ -89180,6 +93054,9 @@
xref: RHEA:23096
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.49
+property_value: skos:exactMatch RHEA:23096
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008903
@@ -89193,6 +93070,9 @@
xref: MetaCyc:RXN0-305
xref: RHEA:11952
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.22
+property_value: skos:exactMatch RHEA:11952
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008904
@@ -89210,6 +93090,9 @@
xref: MetaCyc:HYGROMYCIN-B-KINASE-RXN
xref: RHEA:23388
is_a: GO:0034071 ! aminoglycoside phosphotransferase activity
+property_value: skos:exactMatch EC:2.7.1.119
+property_value: skos:exactMatch RHEA:23388
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008905
@@ -89235,6 +93118,8 @@
xref: RHEA:21140
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:broadMatch EC:2.7.1.73
+property_value: skos:exactMatch RHEA:21140
[Term]
id: GO:0008907
@@ -89261,6 +93146,9 @@
xref: MetaCyc:ISOCHORMAT-RXN
xref: RHEA:11112
is_a: GO:0004463 ! leukotriene-A4 hydrolase activity
+property_value: skos:exactMatch EC:3.3.2.1
+property_value: skos:exactMatch RHEA:11112
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008909
@@ -89275,6 +93163,9 @@
xref: MetaCyc:ISOCHORSYN-RXN
xref: RHEA:18985
is_a: GO:0050486 ! intramolecular hydroxytransferase activity
+property_value: skos:exactMatch EC:5.4.4.2
+property_value: skos:exactMatch RHEA:18985
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008910
@@ -89292,6 +93183,9 @@
xref: MetaCyc:KANAMYCIN-KINASE-RXN
xref: RHEA:24256
is_a: GO:0034071 ! aminoglycoside phosphotransferase activity
+property_value: skos:exactMatch EC:2.7.1.95
+property_value: skos:exactMatch RHEA:24256
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008911
@@ -89305,6 +93199,9 @@
xref: MetaCyc:LACTALDDEHYDROG-RXN
xref: RHEA:14277
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.22
+property_value: skos:exactMatch RHEA:14277
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008912
@@ -89317,6 +93214,8 @@
synonym: "propanediol:nicotinamide adenine dinucleotide (NAD) oxidoreductase activity" RELATED [EC:1.1.1.77]
xref: EC:1.1.1.77
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.77
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008913
@@ -89329,8 +93228,14 @@
synonym: "lauroyl transferase activity" RELATED []
synonym: "lauroyltransferase activity" RELATED []
xref: EC:2.3.1.241
+xref: RHEA:28442
+xref: RHEA:69396
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.241
+property_value: skos:narrowMatch RHEA:28442
+property_value: skos:narrowMatch RHEA:69396
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28340" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008914
@@ -89343,11 +93248,17 @@
synonym: "leucyltransferase activity" RELATED [EC:2.3.2.6]
xref: EC:2.3.2.6
xref: MetaCyc:LEUCYLTRANSFERASE-RXN
+xref: RHEA:12340
+xref: RHEA:50416
is_a: GO:0016755 ! aminoacyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.3.2.6
+property_value: skos:narrowMatch RHEA:12340
+property_value: skos:narrowMatch RHEA:50416
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30124" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008915
@@ -89361,7 +93272,10 @@
xref: RHEA:67828
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.182
+property_value: skos:exactMatch RHEA:67828
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30154" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008917
@@ -89376,6 +93290,8 @@
xref: MetaCyc:RXN-22502
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
relationship: part_of GO:0009103 ! lipopolysaccharide biosynthetic process
+property_value: skos:exactMatch EC:2.4.1.56
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008918
@@ -89396,6 +93312,8 @@
xref: MetaCyc:RXN-22172
is_a: GO:0035250 ! UDP-galactosyltransferase activity
relationship: part_of GO:0009103 ! lipopolysaccharide biosynthetic process
+property_value: skos:exactMatch EC:2.4.1.44
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008919
@@ -89414,6 +93332,9 @@
xref: RHEA:30015
is_a: GO:0035251 ! UDP-glucosyltransferase activity
relationship: part_of GO:0009103 ! lipopolysaccharide biosynthetic process
+property_value: skos:exactMatch EC:2.4.1.58
+property_value: skos:exactMatch MetaCyc:RXN0-5126
+property_value: skos:exactMatch RHEA:30015
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -89457,7 +93378,10 @@
xref: MetaCyc:ACYLACPSYNTH-RXN
xref: RHEA:45588
is_a: GO:0015645 ! fatty acid ligase activity
+property_value: skos:exactMatch EC:6.2.1.20
+property_value: skos:exactMatch RHEA:45588
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008923
@@ -89470,7 +93394,10 @@
xref: MetaCyc:LYSDECARBOX-RXN
xref: RHEA:22352
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.18
+property_value: skos:exactMatch RHEA:22352
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22382" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008924
@@ -89483,9 +93410,16 @@
synonym: "MQO activity" BROAD [EC:1.1.5.4]
xref: EC:1.1.5.4
xref: MetaCyc:MALATE-DEHYDROGENASE-ACCEPTOR-RXN
+xref: MetaCyc:RXNI-3
+xref: RHEA:30095
xref: RHEA:46012
is_a: GO:0016615 ! malate dehydrogenase activity
is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.1.5.4
+property_value: skos:exactMatch MetaCyc:MALATE-DEHYDROGENASE-ACCEPTOR-RXN
+property_value: skos:exactMatch RHEA:46012
+property_value: skos:narrowMatch MetaCyc:RXNI-3
+property_value: skos:narrowMatch RHEA:30095
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -89500,6 +93434,9 @@
xref: MetaCyc:MALTACETYLTRAN-RXN
xref: RHEA:10456
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.79
+property_value: skos:exactMatch RHEA:10456
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008926
@@ -89511,7 +93448,11 @@
xref: MetaCyc:MANNPDEHYDROG-RXN
xref: RHEA:19661
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.17
+property_value: skos:exactMatch RHEA:19661
+property_value: skos:relatedMatch MetaCyc:MANNIDEG-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008927
@@ -89530,6 +93471,9 @@
xref: MetaCyc:MANNONDEHYDRAT-RXN
xref: RHEA:20097
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.8
+property_value: skos:exactMatch RHEA:20097
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008928
@@ -89552,6 +93496,9 @@
xref: MetaCyc:MANNPGUANYLTRANGDP-RXN
xref: RHEA:12905
is_a: GO:0070568 ! guanylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.22
+property_value: skos:exactMatch RHEA:12905
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008929
@@ -89566,6 +93513,9 @@
xref: MetaCyc:METHGLYSYN-RXN
xref: RHEA:17937
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.3
+property_value: skos:exactMatch RHEA:17937
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008930
@@ -89581,6 +93531,9 @@
xref: MetaCyc:METHYLTHIOADENOSINE-NUCLEOSIDASE-RXN
xref: RHEA:13617
is_a: GO:0008477 ! purine nucleosidase activity
+property_value: skos:exactMatch EC:3.2.2.16
+property_value: skos:exactMatch RHEA:13617
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008931
@@ -89600,6 +93553,7 @@
synonym: "murein lytic endotransglycosylase E activity" NARROW []
xref: EC:4.2.2.n2
is_a: GO:0008933 ! peptidoglycan lytic transglycosylase activity
+property_value: skos:exactMatch EC:4.2.2.n2
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21167" xsd:anyURI
[Term]
@@ -89613,6 +93567,7 @@
xref: EC:4.2.2.29
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
is_a: GO:0061783 ! peptidoglycan muralytic activity
+property_value: skos:exactMatch EC:4.2.2.29
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21167" xsd:anyURI
[Term]
@@ -89631,7 +93586,9 @@
xref: Reactome:R-HSA-1855154 "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol"
xref: RHEA:27670
is_a: GO:0052834 ! inositol monophosphate phosphatase activity
+property_value: skos:exactMatch RHEA:27670
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008935
@@ -89648,6 +93605,8 @@
xref: MetaCyc:NAPHTHOATE-SYN-RXN
xref: RHEA:26562
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.36
+property_value: skos:exactMatch RHEA:26562
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21763" xsd:anyURI
[Term]
@@ -89665,6 +93624,8 @@
xref: MetaCyc:NICOTINAMID-RXN
xref: RHEA:14545
is_a: GO:0004040 ! amidase activity
+property_value: skos:exactMatch EC:3.5.1.19
+property_value: skos:exactMatch RHEA:14545
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29467" xsd:anyURI
@@ -89692,6 +93653,9 @@
xref: RHEA:20241
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.7
+property_value: skos:exactMatch RHEA:20241
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008939
@@ -89711,6 +93675,9 @@
xref: MetaCyc:DMBPPRIBOSYLTRANS-RXN
xref: RHEA:11196
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.21
+property_value: skos:exactMatch RHEA:11196
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008940
@@ -89723,7 +93690,9 @@
synonym: "respiratory nitrate reductase activity" NARROW []
xref: RHEA:21068
is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors
+property_value: skos:exactMatch RHEA:21068
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008941
@@ -89736,8 +93705,14 @@
xref: EC:1.14.12.17
xref: MetaCyc:R621-RXN
xref: Reactome:R-HSA-1222723 "Nitric oxide is oxidized to nitrate"
+xref: RHEA:19465
+xref: RHEA:19469
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.17
+property_value: skos:narrowMatch RHEA:19465
+property_value: skos:narrowMatch RHEA:19469
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26482" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008942
@@ -89758,6 +93733,7 @@
xref: MetaCyc:RXN0-6377
is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
is_a: GO:0098809 ! nitrite reductase activity
+property_value: skos:exactMatch EC:1.7.1.4
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25985" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28557" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30026" xsd:anyURI
@@ -89807,7 +93783,9 @@
comment: This term was obsoleted because it corresponds to an assay.
xref: EC:3.1.13.3
xref: MetaCyc:3.1.13.3-RXN
+property_value: skos:exactMatch EC:3.1.13.3
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
is_obsolete: true
[Term]
@@ -89837,6 +93815,11 @@
xref: Reactome:R-HSA-9861660 "ME1 tetramer decarboxylates OA to PYR"
xref: RHEA:15641
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:broadMatch EC:1.1.1.38
+property_value: skos:broadMatch EC:1.1.1.40
+property_value: skos:exactMatch EC:4.1.1.112
+property_value: skos:exactMatch MetaCyc:OXALODECARB-RXN
+property_value: skos:exactMatch RHEA:15641
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28245" xsd:anyURI
[Term]
@@ -89852,6 +93835,9 @@
xref: MetaCyc:OXALYL-COA-DECARBOXYLASE-RXN
xref: RHEA:19333
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.8
+property_value: skos:exactMatch RHEA:19333
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008950
@@ -89873,6 +93859,8 @@
xref: MetaCyc:PALMITOTRANS-RXN
xref: RHEA:44012
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch RHEA:44012
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008953
@@ -89891,6 +93879,9 @@
xref: MetaCyc:PENICILLIN-AMIDASE-RXN
xref: RHEA:18693
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.11
+property_value: skos:exactMatch RHEA:18693
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008954
@@ -89916,10 +93907,12 @@
synonym: "undecaprenyldiphospho-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase activity" RELATED [EC:2.4.99.28]
xref: EC:2.4.99.28
xref: MetaCyc:RXN-14712
-xref: Reactome:R-HSA-9911463 "MrcB elongates peptidoglycan"
xref: RHEA:23708
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.99.28
+property_value: skos:exactMatch RHEA:23708
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28006" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008956
@@ -89943,6 +93936,9 @@
xref: RHEA:21392
xref: UM-BBD_reactionID:r0035
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.39
+property_value: skos:exactMatch RHEA:21392
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008959
@@ -89957,6 +93953,9 @@
xref: MetaCyc:PHOSACETYLTRANS-RXN
xref: RHEA:19521
is_a: GO:0016407 ! acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.8
+property_value: skos:exactMatch RHEA:19521
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008960
@@ -89970,6 +93969,8 @@
xref: EC:2.7.8.20
xref: MetaCyc:PGLYCEROLTRANSI-RXN
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.20
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008961
@@ -89980,6 +93981,9 @@
xref: RHEA:56712
is_a: GO:0016757 ! glycosyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.5.1.145
+property_value: skos:exactMatch RHEA:56712
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008962
@@ -89994,7 +93998,11 @@
xref: MetaCyc:PGPPHOSPHA-RXN
xref: Reactome:R-HSA-1483197 "PTPMT1 dephosphorylates PGP to PG"
xref: RHEA:16725
+xref: RHEA:33752
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.27
+property_value: skos:exactMatch RHEA:16725
+property_value: skos:narrowMatch RHEA:33752
[Term]
id: GO:0008963
@@ -90018,6 +94026,8 @@
xref: MetaCyc:RXN-8975
xref: RHEA:21920
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:broadMatch EC:2.7.8.13
+property_value: skos:exactMatch RHEA:21920
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -90037,6 +94047,9 @@
xref: MetaCyc:PEPCARBOX-RXN
xref: RHEA:28370
is_a: GO:0004611 ! phosphoenolpyruvate carboxykinase activity
+property_value: skos:exactMatch EC:4.1.1.31
+property_value: skos:exactMatch RHEA:28370
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008965
@@ -90055,6 +94068,9 @@
xref: MetaCyc:2.7.3.9-RXN
xref: RHEA:23880
is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor
+property_value: skos:exactMatch EC:2.7.3.9
+property_value: skos:exactMatch RHEA:23880
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008966
@@ -90068,6 +94084,9 @@
xref: MetaCyc:5.4.2.10-RXN
xref: RHEA:23424
is_a: GO:0016868 ! intramolecular phosphotransferase activity
+property_value: skos:exactMatch EC:5.4.2.10
+property_value: skos:exactMatch RHEA:23424
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008967
@@ -90084,6 +94103,9 @@
xref: MetaCyc:GPH-RXN
xref: RHEA:14369
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.18
+property_value: skos:exactMatch RHEA:14369
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008968
@@ -90094,15 +94116,19 @@
xref: MetaCyc:RXN0-4301
xref: RHEA:27489
is_a: GO:0016868 ! intramolecular phosphotransferase activity
+property_value: skos:exactMatch RHEA:27489
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008970
-name: phospholipase A1 activity
+name: glycerophospholipid phospholipase A1 activity
namespace: molecular_function
-def: "Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H+." [RHEA:18689]
+def: "Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = a 2-acyl-sn-glycero-3-phospholipid + a fatty acid + H+. Note that the substrate has a diacyl group attached to the glycerol group." [RHEA:67424]
subset: goslim_chembl
-synonym: "phosphatidylcholine 1-acylhydrolase activity" EXACT []
+synonym: "diacylphospholipase A1 activity" BROAD []
+synonym: "phosphatidylcholine 1-acylhydrolase activity" NARROW []
synonym: "phosphatidylserine 1-acylhydrolase activity" NARROW []
+synonym: "phospholipase A1 activity" RELATED []
xref: EC:3.1.1.32
xref: MetaCyc:PHOSPHOLIPASE-A1-RXN
xref: Reactome:R-HSA-1482827 "PC is hydrolyzed to 2-acyl LPC by PLA2G4C"
@@ -90113,10 +94139,10 @@
xref: Reactome:R-HSA-1482920 "PG is hydrolyzed to 2-acyl LPG by PLA2[14]"
xref: Reactome:R-HSA-1482932 "PI is hydrolyzed to 2-acyl LPI by PLA2[13]"
xref: Reactome:R-HSA-5694485 "ABHD3 hydrolyses LPC(14:0) to 1AGPC"
-xref: Reactome:R-HSA-8869425 "PLA1A hydrolyses PS to 2-acyl LPS"
-xref: RHEA:18689
-is_a: GO:0004620 ! phospholipase activity
-is_a: GO:0052689 ! carboxylic ester hydrolase activity
+xref: RHEA:67424
+is_a: GO:0140322 ! A1-type glycerophospholipase activity
+property_value: skos:exactMatch EC:3.1.1.32
+property_value: skos:exactMatch RHEA:67424
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28339" xsd:anyURI
[Term]
@@ -90131,6 +94157,9 @@
xref: RHEA:19893
is_a: GO:0016301 ! kinase activity
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
+property_value: skos:exactMatch EC:2.7.4.7
+property_value: skos:exactMatch RHEA:19893
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008973
@@ -90148,7 +94177,12 @@
xref: MetaCyc:PPENTOMUT-RXN
xref: Reactome:R-HSA-6787329 "PGM2:Mg2+ isomerises R1P to R5P"
xref: Reactome:R-HSA-8982667 "PGM2:Mg2+ isomerises dR1P to dR5P"
+xref: RHEA:18793
+xref: RHEA:27658
is_a: GO:0016868 ! intramolecular phosphotransferase activity
+property_value: skos:exactMatch EC:5.4.2.7
+property_value: skos:narrowMatch RHEA:18793
+property_value: skos:narrowMatch RHEA:27658
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
[Term]
@@ -90171,6 +94205,9 @@
xref: RHEA:19365
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.19
+property_value: skos:exactMatch RHEA:19365
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008975
@@ -90202,6 +94239,9 @@
xref: RHEA:19573
is_a: GO:0016301 ! kinase activity
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
+property_value: skos:exactMatch EC:2.7.4.1
+property_value: skos:exactMatch RHEA:19573
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008977
@@ -90216,6 +94256,9 @@
xref: MetaCyc:PREPHENATEDEHYDROG-RXN
xref: RHEA:13869
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.12
+property_value: skos:exactMatch RHEA:13869
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008978
@@ -90249,6 +94292,9 @@
xref: RHEA:23148
is_a: GO:0016301 ! kinase activity
is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor
+property_value: skos:exactMatch EC:2.7.2.15
+property_value: skos:exactMatch RHEA:23148
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008981
@@ -90311,6 +94357,9 @@
xref: RHEA:24452
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
is_a: GO:0051998 ! protein carboxyl O-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.80
+property_value: skos:exactMatch RHEA:24452
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008984
@@ -90328,6 +94377,9 @@
xref: RESID:AA0072
xref: RHEA:23236
is_a: GO:0051723 ! protein methylesterase activity
+property_value: skos:exactMatch EC:3.1.1.61
+property_value: skos:exactMatch RHEA:23236
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008985
@@ -90363,6 +94415,8 @@
xref: RHEA:11364
is_a: GO:0016301 ! kinase activity
is_a: GO:0016781 ! phosphotransferase activity, paired acceptors
+property_value: skos:exactMatch EC:2.7.9.2
+property_value: skos:exactMatch RHEA:11364
[Term]
id: GO:0008987
@@ -90373,6 +94427,8 @@
xref: RHEA:25888
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
relationship: part_of GO:0019805 ! quinolinate biosynthetic process
+property_value: skos:exactMatch RHEA:25888
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008988
@@ -90389,6 +94445,7 @@
xref: RHEA:58728
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0016433 ! rRNA (adenine) methyltransferase activity
+property_value: skos:exactMatch RHEA:58728
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
[Term]
@@ -90456,6 +94513,9 @@
xref: RHEA:20117
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.5
+property_value: skos:exactMatch RHEA:20117
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008994
@@ -90471,6 +94531,9 @@
xref: MetaCyc:RHAMNULPALDOL-RXN
xref: RHEA:19689
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.19
+property_value: skos:exactMatch RHEA:19689
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008995
@@ -90481,8 +94544,10 @@
xref: EC:3.1.26.12
xref: MetaCyc:3.1.26.12-RXN
is_a: GO:0016891 ! RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
+property_value: skos:exactMatch EC:3.1.26.12
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29880" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008996
@@ -90517,7 +94582,10 @@
xref: MetaCyc:1.17.4.2-RXN
xref: RHEA:12701
is_a: GO:0016728 ! oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor
+property_value: skos:exactMatch EC:1.17.4.2
+property_value: skos:exactMatch RHEA:12701
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28055" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0008999
@@ -90528,9 +94596,15 @@
synonym: "peptide-alanine-alpha-N-acetyltransferase activity" EXACT []
synonym: "ribosomal protein S18 acetyltransferase activity" RELATED []
synonym: "ribosomal-protein-alanine N-acetyltransferase activity" BROAD []
+xref: EC:2.3.1.266
+xref: EC:2.3.1.267
xref: MetaCyc:RXN-17860
xref: RHEA:50500
is_a: GO:0004596 ! protein-N-terminal amino-acid acetyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-17860
+property_value: skos:exactMatch RHEA:50500
+property_value: skos:narrowMatch EC:2.3.1.266
+property_value: skos:narrowMatch EC:2.3.1.267
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23472" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27532" xsd:anyURI
@@ -90547,6 +94621,9 @@
xref: Reactome:R-HSA-2408524 "Sec is reduced to H2Se by PXLP-K259-SCLY dimer"
xref: RHEA:11632
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.16
+property_value: skos:exactMatch RHEA:11632
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009001
@@ -90564,6 +94641,8 @@
xref: RHEA:24560
is_a: GO:0016412 ! serine O-acyltransferase activity
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.30
+property_value: skos:exactMatch RHEA:24560
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -90583,6 +94662,8 @@
xref: EC:3.4.16.4
xref: MetaCyc:3.4.16.4-RXN
is_a: GO:0004185 ! serine-type carboxypeptidase activity
+property_value: skos:exactMatch EC:3.4.16.4
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009003
@@ -90590,7 +94671,9 @@
namespace: molecular_function
def: "An endopeptidase that cleaves a hydrophobic, N-terminal signal or leader sequences from mitochondrial, secreted and periplasmic proteins." [GOC:vw]
comment: Note that this term was reinstated from obsolete.
+xref: EC:3.4.21.89
is_a: GO:0004175 ! endopeptidase activity
+property_value: skos:narrowMatch EC:3.4.21.89
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30479" xsd:anyURI
[Term]
@@ -90671,6 +94754,9 @@
xref: RHEA:15197
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
is_a: GO:0009008 ! DNA-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.72
+property_value: skos:exactMatch RHEA:15197
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009008
@@ -90718,6 +94804,9 @@
xref: MetaCyc:SORB6PDEHYDROG-RXN
xref: RHEA:19837
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.140
+property_value: skos:exactMatch RHEA:19837
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009011
@@ -90742,7 +94831,10 @@
xref: MetaCyc:GLYCOGENSYN-RXN
xref: RHEA:18189
is_a: GO:0033840 ! alpha-1,4-glucan glucosyltransferase (NDP-glucose donor) activity
+property_value: skos:exactMatch EC:2.4.1.21
+property_value: skos:exactMatch RHEA:18189
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28271" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009012
@@ -90757,6 +94849,9 @@
xref: MetaCyc:STREPTOMYCIN-3-ADENYLYLTRANSFERASE-RXN
xref: RHEA:20245
is_a: GO:0034068 ! aminoglycoside nucleotidyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.47
+property_value: skos:exactMatch RHEA:20245
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009013
@@ -90768,7 +94863,9 @@
xref: EC:1.2.1.16
xref: UM-BBD_reactionID:r0371
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.16
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25781" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009014
@@ -90782,6 +94879,9 @@
xref: MetaCyc:SUCCDIAMINOPIMDESUCC-RXN
xref: RHEA:22608
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.18
+property_value: skos:exactMatch RHEA:22608
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009015
@@ -90801,6 +94901,9 @@
xref: MetaCyc:SUCCARGDIHYDRO-RXN
xref: RHEA:19533
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.23
+property_value: skos:exactMatch RHEA:19533
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009016
@@ -90816,6 +94919,9 @@
xref: MetaCyc:SUCCINYLDIAMINOPIMTRANS-RXN
xref: RHEA:11960
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.17
+property_value: skos:exactMatch RHEA:11960
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009017
@@ -90831,6 +94937,9 @@
xref: MetaCyc:SUCCGLUDESUCC-RXN
xref: RHEA:15169
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.96
+property_value: skos:exactMatch RHEA:15169
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009018
@@ -90844,6 +94953,9 @@
xref: MetaCyc:SUCROSE-PHOSPHORYLASE-RXN
xref: RHEA:24048
is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity
+property_value: skos:exactMatch EC:2.4.1.7
+property_value: skos:exactMatch RHEA:24048
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009019
@@ -90885,8 +94997,11 @@
xref: RHEA:10628
is_a: GO:0016779 ! nucleotidyltransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.7.7.56
+property_value: skos:exactMatch RHEA:10628
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19854" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009023
@@ -90896,8 +95011,7 @@
synonym: "tRNA sulfurtransferase" EXACT []
synonym: "tRNA sulphurtransferase activity" EXACT []
is_obsolete: true
-replaced_by: GO:0034227
-consider: GO:0016783
+replaced_by: GO:0140741
[Term]
id: GO:0009024
@@ -90911,6 +95025,9 @@
xref: RHEA:12420
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.144
+property_value: skos:exactMatch RHEA:12420
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009025
@@ -90930,6 +95047,9 @@
xref: MetaCyc:TAGAALDOL-RXN
xref: RHEA:22948
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.40
+property_value: skos:exactMatch RHEA:22948
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009026
@@ -90948,6 +95068,9 @@
xref: MetaCyc:ALTRO-OXIDOREDUCT-RXN
xref: RHEA:17813
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.58
+property_value: skos:exactMatch RHEA:17813
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009027
@@ -90960,6 +95083,9 @@
xref: MetaCyc:TARTRATE-DEHYDROGENASE-RXN
xref: RHEA:15209
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.93
+property_value: skos:exactMatch RHEA:15209
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009028
@@ -90980,6 +95106,9 @@
xref: MetaCyc:GLYOCARBOLIG-RXN
xref: RHEA:10136
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.47
+property_value: skos:exactMatch RHEA:10136
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009029
@@ -90994,7 +95123,10 @@
xref: RHEA:67840
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.130
+property_value: skos:exactMatch RHEA:67840
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30158" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009030
@@ -91014,6 +95146,9 @@
xref: RHEA:15913
is_a: GO:0016301 ! kinase activity
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
+property_value: skos:exactMatch EC:2.7.4.16
+property_value: skos:exactMatch RHEA:15913
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009032
@@ -91028,6 +95163,9 @@
xref: MetaCyc:THYM-PHOSPH-RXN
xref: RHEA:16037
is_a: GO:0016154 ! pyrimidine-nucleoside phosphorylase activity
+property_value: skos:exactMatch EC:2.4.2.4
+property_value: skos:exactMatch RHEA:16037
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009033
@@ -91062,6 +95200,11 @@
xref: RHEA:19553
is_a: GO:0016830 ! carbon-carbon lyase activity
relationship: part_of GO:0006569 ! L-tryptophan catabolic process
+property_value: skos:exactMatch EC:4.1.99.1
+property_value: skos:exactMatch KEGG_REACTION:R00673
+property_value: skos:exactMatch MetaCyc:TRYPTOPHAN-RXN
+property_value: skos:exactMatch RHEA:19553
+property_value: skos:relatedMatch MetaCyc:TRYPDEG-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -91079,7 +95222,9 @@
is_a: GO:0015616 ! DNA translocase activity
is_a: GO:0015666 ! restriction endodeoxyribonuclease activity
is_a: GO:0016888 ! DNA endonuclease activity, producing 5'-phosphomonoesters
+property_value: skos:exactMatch EC:3.1.21.3
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21612" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009036
@@ -91091,6 +95236,8 @@
xref: MetaCyc:3.1.21.4-RXN
is_a: GO:0015666 ! restriction endodeoxyribonuclease activity
is_a: GO:0016888 ! DNA endonuclease activity, producing 5'-phosphomonoesters
+property_value: skos:exactMatch EC:3.1.21.4
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009037
@@ -91130,6 +95277,9 @@
xref: RHEA:20557
xref: UM-BBD_reactionID:r0120
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.5
+property_value: skos:exactMatch RHEA:20557
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009040
@@ -91140,6 +95290,8 @@
xref: EC:1.1.1.154
xref: MetaCyc:R165-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.154
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009041
@@ -91170,6 +95322,9 @@
xref: MetaCyc:VALINE-PYRUVATE-AMINOTRANSFER-RXN
xref: RHEA:22912
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.66
+property_value: skos:exactMatch RHEA:22912
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009044
@@ -91186,6 +95341,8 @@
xref: EC:3.2.1.37
xref: MetaCyc:3.2.1.37-RXN
is_a: GO:0097599 ! xylanase activity
+property_value: skos:exactMatch EC:3.2.1.37
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009045
@@ -91200,6 +95357,9 @@
xref: MetaCyc:XYLISOM-RXN
xref: RHEA:22816
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.5
+property_value: skos:exactMatch RHEA:22816
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009046
@@ -91216,6 +95376,8 @@
xref: EC:3.4.17.14
xref: MetaCyc:3.4.17.14-RXN
is_a: GO:0004181 ! metallocarboxypeptidase activity
+property_value: skos:exactMatch EC:3.4.17.14
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009047
@@ -91256,7 +95418,6 @@
synonym: "glycopeptide breakdown" EXACT []
synonym: "glycopeptide catabolism" EXACT []
synonym: "glycopeptide degradation" EXACT []
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:1901136 ! carbohydrate derivative catabolic process
[Term]
@@ -91269,12 +95430,16 @@
synonym: "pentose phosphate pathway, oxidative branch" EXACT []
synonym: "pentose phosphate shunt, oxidative branch" EXACT []
synonym: "pentose-phosphate pathway, oxidative branch" EXACT []
+xref: MetaCyc:OXIDATIVEPENT-PWY
+xref: MetaCyc:PWY-7796
is_a: GO:0006740 ! NADPH regeneration
is_a: GO:1901135 ! carbohydrate derivative metabolic process
relationship: has_part GO:0004345 ! glucose-6-phosphate dehydrogenase activity
relationship: has_part GO:0004616 ! phosphogluconate dehydrogenase (decarboxylating) activity
relationship: has_part GO:0017057 ! 6-phosphogluconolactonase activity
relationship: part_of GO:0006098 ! pentose-phosphate shunt
+property_value: skos:narrowMatch MetaCyc:OXIDATIVEPENT-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-7796
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29188" xsd:anyURI
@@ -91287,6 +95452,8 @@
synonym: "pentose phosphate pathway, non-oxidative branch" EXACT []
synonym: "pentose phosphate shunt, non-oxidative branch" EXACT []
synonym: "pentose-phosphate pathway, non-oxidative branch" EXACT []
+xref: MetaCyc:NONOXIPENT-PWY
+xref: MetaCyc:PWY-8178
is_a: GO:0006091 ! generation of precursor metabolites and energy
is_a: GO:0019682 ! glyceraldehyde-3-phosphate metabolic process
relationship: has_part GO:0004750 ! D-ribulose-phosphate 3-epimerase activity
@@ -91294,6 +95461,8 @@
relationship: has_part GO:0004801 ! transaldolase activity
relationship: has_part GO:0004802 ! transketolase activity
relationship: part_of GO:0006098 ! pentose-phosphate shunt
+property_value: skos:narrowMatch MetaCyc:NONOXIPENT-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-8178
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27719" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -91312,6 +95481,7 @@
synonym: "electron donor activity" NARROW []
synonym: "electron transporter activity" RELATED []
xref: Reactome:R-HSA-169260 "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF"
+xref: Reactome:R-HSA-2564826 "4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold"
is_a: GO:0003674 ! molecular_function
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21334" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26572" xsd:anyURI
@@ -91457,13 +95627,14 @@
[Term]
id: GO:0009064
-name: glutamine family amino acid metabolic process
+name: obsolete glutamine family amino acid metabolic process
namespace: biological_process
-def: "The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline." [GOC:ai]
+def: "OBSOLETE. The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline." [GOC:ai]
+comment: The reason for obsoletion is that this is an unnecessary grouping term.
synonym: "glutamine family amino acid metabolism" EXACT []
xref: Reactome:R-HSA-8964539 "Glutamate and glutamine metabolism"
-is_a: GO:0170033 ! L-amino acid metabolic process
-is_a: GO:0170039 ! proteinogenic amino acid metabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29444" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0009065
@@ -91492,13 +95663,16 @@
id: GO:0009067
name: aspartate family amino acid biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine." [GOC:ai]
+def: "The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine." [GOC:ai, MetaCyc:PWY0-781]
synonym: "aspartate family amino acid anabolism" EXACT []
synonym: "aspartate family amino acid biosynthesis" EXACT []
synonym: "aspartate family amino acid formation" EXACT []
synonym: "aspartate family amino acid synthesis" EXACT []
+xref: MetaCyc:PWY0-781
is_a: GO:0170034 ! L-amino acid biosynthetic process
is_a: GO:0170038 ! proteinogenic amino acid biosynthetic process
+property_value: skos:exactMatch MetaCyc:PWY0-781
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29444" xsd:anyURI
[Term]
id: GO:0009068
@@ -91531,7 +95705,14 @@
synonym: "serine family amino acid biosynthesis" EXACT []
synonym: "serine family amino acid formation" EXACT []
synonym: "serine family amino acid synthesis" EXACT []
+xref: MetaCyc:PWY-6292
+xref: MetaCyc:SER-GLYSYN-PWY
+xref: MetaCyc:SULFATE-CYS-PWY
is_a: GO:1901607 ! alpha-amino acid biosynthetic process
+property_value: skos:narrowMatch MetaCyc:PWY-6292
+property_value: skos:narrowMatch MetaCyc:SER-GLYSYN-PWY
+property_value: skos:narrowMatch MetaCyc:SULFATE-CYS-PWY
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29444" xsd:anyURI
[Term]
id: GO:0009071
@@ -91693,22 +95874,24 @@
[Term]
id: GO:0009084
-name: glutamine family amino acid biosynthetic process
+name: L-glutamine family amino acid biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline." [GOC:ai]
+def: "The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline." [GOC:ai, MetaCyc:GLUTAMINE-SYN]
synonym: "glutamine family amino acid anabolism" EXACT []
synonym: "glutamine family amino acid biosynthesis" EXACT []
synonym: "glutamine family amino acid formation" EXACT []
synonym: "glutamine family amino acid synthesis" EXACT []
-is_a: GO:0009064 ! glutamine family amino acid metabolic process
+xref: MetaCyc:GLUTAMINE-SYN
is_a: GO:0170034 ! L-amino acid biosynthetic process
is_a: GO:0170038 ! proteinogenic amino acid biosynthetic process
+property_value: skos:exactMatch MetaCyc:GLUTAMINE-SYN
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29444" xsd:anyURI
[Term]
id: GO:0009085
-name: lysine biosynthetic process
+name: L-lysine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid." [GOC:go_curators]
+def: "The chemical reactions and pathways resulting in the formation of L-lysine, 2,6-diaminohexanoic acid." [GOC:go_curators, MetaCyc:LYSINE-SYN]
synonym: "lysine anabolism" EXACT []
synonym: "lysine biosynthesis" EXACT []
synonym: "lysine formation" EXACT []
@@ -91716,20 +95899,23 @@
xref: MetaCyc:LYSINE-SYN
is_a: GO:0006553 ! lysine metabolic process
is_a: GO:0009067 ! aspartate family amino acid biosynthetic process
+property_value: skos:exactMatch MetaCyc:LYSINE-SYN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30820" xsd:anyURI
[Term]
id: GO:0009086
-name: methionine biosynthetic process
+name: obsolete methionine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the de novo formation of L-methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
synonym: "methionine anabolism" EXACT []
synonym: "methionine biosynthesis" EXACT []
synonym: "methionine formation" EXACT []
synonym: "methionine synthesis" EXACT []
-is_a: GO:0000097 ! sulfur amino acid biosynthetic process
-is_a: GO:0006555 ! methionine metabolic process
-is_a: GO:0009067 ! aspartate family amino acid biosynthetic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31068" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0071265
[Term]
id: GO:0009087
@@ -91748,20 +95934,24 @@
[Term]
id: GO:0009088
-name: threonine biosynthetic process
+name: L-threonine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732]
+def: "The chemical reactions and pathways resulting in the formation of L-threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732, MetaCyc:THRESYN-PWY]
synonym: "threonine anabolism" EXACT []
synonym: "threonine biosynthesis" EXACT []
synonym: "threonine formation" EXACT []
synonym: "threonine synthesis" EXACT []
-is_a: GO:0006566 ! threonine metabolic process
+xref: MetaCyc:HOMOSER-THRESYN-PWY
+xref: MetaCyc:THRESYN-PWY
+is_a: GO:0006566 ! L-threonine metabolic process
is_a: GO:0009067 ! aspartate family amino acid biosynthetic process
+property_value: skos:narrowMatch MetaCyc:HOMOSER-THRESYN-PWY
+property_value: skos:narrowMatch MetaCyc:THRESYN-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
id: GO:0009089
-name: lysine biosynthetic process via diaminopimelate
+name: L-lysine biosynthetic process via diaminopimelate
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate." [GOC:go_curators]
synonym: "diaminopimelate pathway" EXACT []
@@ -91771,20 +95961,23 @@
synonym: "lysine biosynthetic process via diaminopimelic acid" EXACT []
synonym: "lysine formation via diaminopimelate" EXACT []
synonym: "lysine synthesis via diaminopimelate" EXACT []
-is_a: GO:0009085 ! lysine biosynthetic process
+is_a: GO:0009085 ! L-lysine biosynthetic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30820" xsd:anyURI
[Term]
id: GO:0009090
-name: homoserine biosynthetic process
+name: L-homoserine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid." [GOC:go_curators, ISBN:0198506732]
+def: "The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid." [GOC:go_curators, ISBN:0198506732, MetaCyc:HOMOSERSYN-PWY]
synonym: "homoserine anabolism" EXACT []
synonym: "homoserine biosynthesis" EXACT []
synonym: "homoserine formation" EXACT []
synonym: "homoserine synthesis" EXACT []
xref: MetaCyc:HOMOSERSYN-PWY
is_a: GO:0009070 ! serine family amino acid biosynthetic process
-is_a: GO:0009092 ! homoserine metabolic process
+is_a: GO:0170034 ! L-amino acid biosynthetic process
+is_a: GO:0170043 ! non-proteinogenic amino acid biosynthetic process
+property_value: skos:exactMatch MetaCyc:HOMOSERSYN-PWY
[Term]
id: GO:0009091
@@ -91808,16 +96001,17 @@
[Term]
id: GO:0009093
-name: cysteine catabolic process
+name: obsolete cysteine catabolic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of cysteine, 2-amino-3-mercaptopropanoic acid." [GOC:go_curators]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of cysteine, 2-amino-3-mercaptopropanoic acid." [GOC:go_curators]
+comment: The reason for obsoletion is that a more specific term has been created.
synonym: "cysteine breakdown" EXACT []
synonym: "cysteine catabolism" EXACT []
synonym: "cysteine degradation" EXACT []
xref: Wikipedia:Cysteine
-is_a: GO:0000098 ! sulfur amino acid catabolic process
-is_a: GO:0006534 ! cysteine metabolic process
-is_a: GO:1901606 ! alpha-amino acid catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31068" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0019448
[Term]
id: GO:0009094
@@ -91835,7 +96029,7 @@
synonym: "phenylalanine biosynthetic process, prephenate pathway" RELATED []
synonym: "phenylalanine biosynthetic process, shikimate pathway" RELATED []
is_a: GO:0006558 ! L-phenylalanine metabolic process
-is_a: GO:0009095 ! aromatic amino acid family biosynthetic process, prephenate pathway
+is_a: GO:0009073 ! aromatic amino acid family biosynthetic process
is_a: GO:0170034 ! L-amino acid biosynthetic process
is_a: GO:0170038 ! proteinogenic amino acid biosynthetic process
@@ -91843,13 +96037,15 @@
id: GO:0009095
name: aromatic amino acid family biosynthetic process, prephenate pathway
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of phenylalanine and tyrosine from other compounds, including chorismate, via the intermediate prephenate." [GOC:mah, ISBN:0471331309]
+def: "The chemical reactions and pathways resulting in the formation of phenylalanine and tyrosine from other compounds, including chorismate, via the intermediate prephenate." [GOC:mah, ISBN:0471331309, MetaCyc:PWY-3481]
synonym: "aromatic amino acid family anabolism, prephenate pathway" EXACT []
synonym: "aromatic amino acid family biosynthetic process via prephenate" EXACT [GOC:pr]
synonym: "aromatic amino acid family biosynthetic process via prephenate(2-)" EXACT [GOC:pr]
synonym: "aromatic amino acid family formation, prephenate pathway" EXACT []
synonym: "aromatic amino acid family synthesis, prephenate pathway" EXACT []
+xref: MetaCyc:PWY-3481
is_a: GO:0009073 ! aromatic amino acid family biosynthetic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31091" xsd:anyURI
[Term]
id: GO:0009097
@@ -91869,7 +96065,7 @@
id: GO:0009098
name: L-leucine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of L-leucine, 2-amino-4-methylpentanoic acid." [GOC:ai]
+def: "The chemical reactions and pathways resulting in the formation of L-leucine, 2-amino-4-methylpentanoic acid." [GOC:ai, MetaCyc:LEUSYN-PWY]
synonym: "L-leucine anabolism" EXACT []
synonym: "L-leucine biosynthesis" EXACT []
synonym: "L-leucine formation" EXACT []
@@ -91879,12 +96075,13 @@
is_a: GO:0006551 ! L-leucine metabolic process
is_a: GO:0009079 ! pyruvate family amino acid biosynthetic process
is_a: GO:0009082 ! branched-chain amino acid biosynthetic process
+property_value: skos:exactMatch MetaCyc:LEUSYN-PWY
[Term]
id: GO:0009099
name: L-valine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid." [GOC:ai]
+def: "The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid." [GOC:ai, MetaCyc:VALSYN-PWY]
synonym: "valine anabolism" EXACT []
synonym: "valine biosynthesis" EXACT []
synonym: "valine formation" EXACT []
@@ -91942,7 +96139,6 @@
xref: MetaCyc:BIOTIN-SYN
is_a: GO:0006768 ! biotin metabolic process
is_a: GO:0042364 ! water-soluble vitamin biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0044272 ! sulfur compound biosynthetic process
is_a: GO:0072330 ! monocarboxylic acid biosynthetic process
@@ -93573,7 +97769,7 @@
synonym: "glycolipid synthesis" EXACT []
xref: MetaCyc:PWY-401
is_a: GO:0006664 ! glycolipid metabolic process
-is_a: GO:0046467 ! membrane lipid biosynthetic process
+is_a: GO:0008610 ! lipid biosynthetic process
is_a: GO:1901137 ! carbohydrate derivative biosynthetic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28573" xsd:anyURI
@@ -93702,9 +97898,13 @@
synonym: "10-formyltetrahydrofolate biosynthesis" EXACT []
synonym: "10-formyltetrahydrofolate formation" EXACT []
synonym: "10-formyltetrahydrofolate synthesis" EXACT []
+xref: MetaCyc:1CMET2-PWY
+xref: MetaCyc:PWY-3841
is_a: GO:0009256 ! 10-formyltetrahydrofolate metabolic process
is_a: GO:0043650 ! dicarboxylic acid biosynthetic process
is_a: GO:0046654 ! tetrahydrofolate biosynthetic process
+property_value: skos:narrowMatch MetaCyc:1CMET2-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-3841
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -94794,7 +98994,6 @@
synonym: "vitamin B7 binding" EXACT []
synonym: "vitamin H binding" EXACT []
is_a: GO:0019842 ! vitamin binding
-is_a: GO:0033218 ! amide binding
is_a: GO:0033293 ! monocarboxylic acid binding
is_a: GO:1901363 ! heterocyclic compound binding
is_a: GO:1901681 ! sulfur compound binding
@@ -94837,6 +99036,7 @@
synonym: "ATP-dependent Holliday junction helicase activity" NARROW []
synonym: "Holliday junction helicase activity" NARROW []
is_a: GO:0003678 ! DNA helicase activity
+property_value: skos:broadMatch EC:3.6.4.12
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pr
creation_date: 2013-08-07T13:36:54Z
@@ -94910,6 +99110,9 @@
xref: RHEA:23832
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.60
+property_value: skos:exactMatch RHEA:23832
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009385
@@ -95969,7 +100172,10 @@
is_a: GO:0009055 ! electron transfer activity
is_a: GO:0015453 ! oxidoreduction-driven active transmembrane transporter activity
is_a: GO:0016675 ! oxidoreductase activity, acting on a heme group of donors
+property_value: skos:exactMatch EC:7.1.1.3
+property_value: skos:exactMatch RHEA:30251
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20924" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009487
@@ -96081,7 +100287,10 @@
is_a: GO:0009055 ! electron transfer activity
is_a: GO:0015453 ! oxidoreduction-driven active transmembrane transporter activity
is_a: GO:0052880 ! oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor
+property_value: skos:exactMatch EC:7.1.1.6
+property_value: skos:exactMatch RHEA:22148
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19015" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009497
@@ -97716,7 +101925,10 @@
is_a: GO:0015078 ! proton transmembrane transporter activity
is_a: GO:0022853 ! active monoatomic ion transmembrane transporter activity
relationship: has_part GO:0004427 ! inorganic diphosphate phosphatase activity
+property_value: skos:exactMatch EC:7.1.3.1
+property_value: skos:exactMatch RHEA:13973
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21272" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009679
@@ -97790,9 +102002,21 @@
synonym: "gibberellic acid formation" NARROW []
synonym: "gibberellic acid synthesis" NARROW []
synonym: "gibberellin biosynthesis" EXACT []
+xref: MetaCyc:PWY-5035
+xref: MetaCyc:PWY-5036
+xref: MetaCyc:PWY-5047
+xref: MetaCyc:PWY-5052
+xref: MetaCyc:PWY-5070
+xref: MetaCyc:PWY-7232
is_a: GO:0009685 ! gibberellin metabolic process
is_a: GO:0016102 ! diterpenoid biosynthetic process
is_a: GO:0046394 ! carboxylic acid biosynthetic process
+property_value: skos:narrowMatch MetaCyc:PWY-5035
+property_value: skos:narrowMatch MetaCyc:PWY-5036
+property_value: skos:narrowMatch MetaCyc:PWY-5047
+property_value: skos:narrowMatch MetaCyc:PWY-5052
+property_value: skos:narrowMatch MetaCyc:PWY-5070
+property_value: skos:narrowMatch MetaCyc:PWY-7232
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -97993,6 +102217,9 @@
xref: RHEA:20153
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.46
+property_value: skos:exactMatch RHEA:20153
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009703
@@ -98013,6 +102240,8 @@
xref: MetaCyc:NITRATE-REDUCTASE-NADH-RXN
xref: RHEA:17913
is_a: GO:0050463 ! nitrate reductase [NAD(P)H] activity
+property_value: skos:exactMatch EC:1.7.1.1
+property_value: skos:exactMatch RHEA:17913
[Term]
id: GO:0009704
@@ -99080,6 +103309,9 @@
xref: MetaCyc:ETHYL-RXN
xref: RHEA:23640
is_a: GO:0016715 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.17.4
+property_value: skos:exactMatch RHEA:23640
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009819
@@ -99150,6 +103382,9 @@
xref: MetaCyc:RXN-4307
xref: RHEA:15285
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.27
+property_value: skos:exactMatch RHEA:15285
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009825
@@ -99987,6 +104222,9 @@
xref: MetaCyc:4.2.3.19-RXN
xref: RHEA:22220
is_a: GO:0010333 ! terpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.19
+property_value: skos:exactMatch RHEA:22220
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009900
@@ -100044,6 +104282,9 @@
xref: MetaCyc:5.5.1.13-RXN
xref: RHEA:14841
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.13
+property_value: skos:exactMatch RHEA:14841
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009906
@@ -100235,8 +104476,11 @@
xref: Reactome:R-HSA-548830 "ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA"
xref: RHEA:32727
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.199
+property_value: skos:exactMatch RHEA:32727
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24752" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25805" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009923
@@ -100760,6 +105004,9 @@
xref: MetaCyc:ADENYLYLSULFATE-REDUCTASE-RXN
xref: RHEA:24240
is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors
+property_value: skos:exactMatch EC:1.8.99.2
+property_value: skos:exactMatch RHEA:24240
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009974
@@ -100787,7 +105034,32 @@
namespace: molecular_function
def: "Catalysis of the reactions: delta-tocopherol = 2-methyl-6-phytyl-1,4-benzene-1,4-diol, gamma-tocopherol = 2,3-dimethyl-6-phytylbenzene-1,4-diol. delta-tocotrienol = 6-geranylgeranyl-2-methylbenzene-1,4-diol gamma-tocotrienol, and = 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol." [EC:5.5.1.24, PMID:12213958]
xref: EC:5.5.1.24
+xref: KEGG_REACTION:R07502
+xref: KEGG_REACTION:R07503
+xref: KEGG_REACTION:R10623
+xref: KEGG_REACTION:R10624
+xref: MetaCyc:RXN-14921
+xref: MetaCyc:RXN-14922
+xref: MetaCyc:RXN-2543
+xref: MetaCyc:RXN-2561
+xref: RHEA:37983
+xref: RHEA:37987
+xref: RHEA:38015
+xref: RHEA:38023
is_a: GO:0009975 ! cyclase activity
+property_value: skos:exactMatch EC:5.5.1.24
+property_value: skos:narrowMatch KEGG_REACTION:R07502
+property_value: skos:narrowMatch KEGG_REACTION:R07503
+property_value: skos:narrowMatch KEGG_REACTION:R10623
+property_value: skos:narrowMatch KEGG_REACTION:R10624
+property_value: skos:narrowMatch MetaCyc:RXN-14921
+property_value: skos:narrowMatch MetaCyc:RXN-14922
+property_value: skos:narrowMatch MetaCyc:RXN-2543
+property_value: skos:narrowMatch MetaCyc:RXN-2561
+property_value: skos:narrowMatch RHEA:37983
+property_value: skos:narrowMatch RHEA:37987
+property_value: skos:narrowMatch RHEA:38015
+property_value: skos:narrowMatch RHEA:38023
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27869" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -100820,7 +105092,12 @@
xref: EC:4.2.1.92
xref: MetaCyc:RXN1F-19
xref: RHEA:25074
+xref: RHEA:25075
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.92
+property_value: skos:exactMatch RHEA:25074
+property_value: skos:narrowMatch RHEA:25075
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009979
@@ -100854,16 +105131,16 @@
alt_id: GO:0016439
def: "Catalysis of the reaction: a uridine in RNA = a pseudouridine in RNA. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5." [GOC:mah, RHEA:48348]
comment: Note that this term should not be confused with 'pseudouridylate synthase activity ; GO:0004730', which refers to the formation of free pseudouridine from uracil and ribose-5-phosphate.
-xref: Reactome:R-HSA-6782381 "PUS1 isoform 2 isomerizes uridine residues to pseudouridine residues in the anticodon stems of tRNAs"
-xref: Reactome:R-HSA-6786583 "PUS7 isomerizes uridine to pseudouridine in tRNAs"
-xref: Reactome:R-HSA-6787566 "PUS1 isoform 1 isomerizes uridine-27, uridine-28 to pseudouridine residues in tRNA(Lys,Ser)"
+xref: Reactome:R-HSA-6782381 "PUS1 isoform 2 transforms uridine residues to pseudouridine in the anticodon stems of tRNAs"
+xref: Reactome:R-HSA-6786583 "PUS7 transforms uridine to pseudouridine in tRNAs"
+xref: Reactome:R-HSA-6787566 "PUS1 isoform 1 transforms uridine-27, uridine-28 yielding pseudouridine in tRNA(Lys,Ser)"
xref: Reactome:R-HSA-6790905 "Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA"
-xref: Reactome:R-HSA-8870289 "PUS3 isomerizes uridine-39 to pseudouridine-39 in tRNA"
-xref: Reactome:R-HSA-9936243 "RPUSD4 in the mitochondrial pseudouridylation module transforms uridine-1397 to pseudouridine-1397 in mitochondrial 16S rRNA"
-xref: Reactome:R-HSA-9937369 "RPUSD3,TRUB2 pseudouridylates MT-CO1,MT-CO3 mRNA"
+xref: Reactome:R-HSA-8870289 "PUS3 transforms uridine-39 to pseudouridine-39 in tRNA"
xref: RHEA:48348
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch RHEA:48348
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26618" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0009983
@@ -101154,7 +105431,6 @@
name: N-1-naphthylphthalamic acid binding
namespace: molecular_function
def: "Binding to N-1-naphthylphthalamic acid, an auxin transport inhibitor." [GOC:sm]
-is_a: GO:0033218 ! amide binding
is_a: GO:0033293 ! monocarboxylic acid binding
[Term]
@@ -102224,14 +106500,14 @@
[Term]
id: GO:0010122
-name: arginine catabolic process to alanine via ornithine
+name: obsolete arginine catabolic process to alanine via ornithine
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including alanine, via ornithine." [GOC:pz]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including alanine, via ornithine." [GOC:pz]
+comment: The reason for obsoletion is that there is no evidence that this function/process/component exists in vivo.
synonym: "arginine breakdown to alanine via ornithine" EXACT []
synonym: "arginine degradation to alanine via ornithine" EXACT []
-is_a: GO:0006522 ! alanine metabolic process
-is_a: GO:0006525 ! arginine metabolic process
-is_a: GO:1901606 ! alpha-amino acid catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31091" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0010123
@@ -102286,7 +106562,11 @@
namespace: biological_process
def: "The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell." [GOC:pz]
synonym: "mycothiol-dependent detoxification of alkylating agent" NARROW []
+xref: MetaCyc:PWY1G-1
+xref: MetaCyc:PWY1G-170
is_a: GO:0098754 ! detoxification
+property_value: skos:narrowMatch MetaCyc:PWY1G-1
+property_value: skos:narrowMatch MetaCyc:PWY1G-170
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -102399,7 +106679,6 @@
synonym: "ureide degradation" EXACT []
xref: MetaCyc:URDEGR-PWY
is_a: GO:0009056 ! catabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0010137
@@ -102410,7 +106689,7 @@
synonym: "ureide biosynthesis" EXACT []
synonym: "ureide formation" EXACT []
synonym: "ureide synthesis" EXACT []
-is_a: GO:0043604 ! amide biosynthetic process
+is_a: GO:0009058 ! biosynthetic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
[Term]
@@ -102766,7 +107045,10 @@
xref: MetaCyc:RXN-2541
xref: RHEA:37975
is_a: GO:0010354 ! homogentisate prenyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.115
+property_value: skos:exactMatch RHEA:37975
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010177
@@ -102776,8 +107058,13 @@
synonym: "2-(2'-methylthio)ethylmalate synthase activity" NARROW []
xref: EC:2.3.3.17
xref: MetaCyc:RXN-18197
+xref: MetaCyc:RXN-2202
xref: RHEA:50624
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.17
+property_value: skos:exactMatch MetaCyc:RXN-18197
+property_value: skos:exactMatch RHEA:50624
+property_value: skos:narrowMatch MetaCyc:RXN-2202
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28855" xsd:anyURI
@@ -103391,6 +107678,10 @@
xref: MetaCyc:PSII-RXN
xref: RHEA:36359
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.10.3.9
+property_value: skos:exactMatch MetaCyc:PSII-RXN
+property_value: skos:exactMatch RHEA:36359
+property_value: skos:relatedMatch MetaCyc:RXN0-5265
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -103690,6 +107981,9 @@
xref: MetaCyc:RXN-7683
xref: RHEA:38055
is_a: GO:0016301 ! kinase activity
+property_value: skos:exactMatch EC:2.7.1.182
+property_value: skos:exactMatch RHEA:38055
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010277
@@ -103706,8 +108000,11 @@
xref: EC:1.14.13.122
xref: RHEA:30359
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
+property_value: skos:exactMatch EC:1.14.13.122
+property_value: skos:exactMatch RHEA:30359
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27676" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010278
@@ -103750,7 +108047,19 @@
name: pinoresinol reductase activity
namespace: molecular_function
def: "Catalysis of the reaction: pinoresinol + NADPH + H+ = lariciresinol + NADP+." [PMID:10066819, PMID:7592828]
+xref: EC:1.23.1.1
+xref: EC:1.23.1.3
+xref: MetaCyc:RXN-8678
+xref: MetaCyc:RXN-8683
+xref: RHEA:34419
+xref: RHEA:34427
is_a: GO:0120546 ! oxidoreductase activity, reducing C-O-C group as acceptor
+property_value: skos:narrowMatch EC:1.23.1.1
+property_value: skos:narrowMatch EC:1.23.1.3
+property_value: skos:narrowMatch MetaCyc:RXN-8678
+property_value: skos:narrowMatch MetaCyc:RXN-8683
+property_value: skos:narrowMatch RHEA:34419
+property_value: skos:narrowMatch RHEA:34427
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
@@ -103759,7 +108068,19 @@
name: lariciresinol reductase activity
namespace: molecular_function
def: "Catalysis of the reaction: lariciresinol + NADPH + H+ = secoisolariciresinol + NADP+." [PMID:10066819, PMID:7592828]
+xref: EC:1.23.1.2
+xref: EC:1.23.1.4
+xref: MetaCyc:RXN-8679
+xref: MetaCyc:RXN-8684
+xref: RHEA:34423
+xref: RHEA:34431
is_a: GO:0120546 ! oxidoreductase activity, reducing C-O-C group as acceptor
+property_value: skos:narrowMatch EC:1.23.1.2
+property_value: skos:narrowMatch EC:1.23.1.4
+property_value: skos:narrowMatch MetaCyc:RXN-8679
+property_value: skos:narrowMatch MetaCyc:RXN-8684
+property_value: skos:narrowMatch RHEA:34423
+property_value: skos:narrowMatch RHEA:34431
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
@@ -103779,6 +108100,9 @@
xref: MetaCyc:RXN-7737
xref: RHEA:23988
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.83
+property_value: skos:exactMatch RHEA:23988
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010286
@@ -103834,7 +108158,10 @@
xref: MetaCyc:RXN1F-152
xref: RHEA:30331
is_a: GO:0004497 ! monooxygenase activity
+property_value: skos:exactMatch EC:1.14.15.24
+property_value: skos:exactMatch RHEA:30331
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29223" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/5604" xsd:anyURI
[Term]
@@ -103861,6 +108188,9 @@
xref: MetaCyc:1.2.3.14-RXN
xref: RHEA:20529
is_a: GO:0018488 ! aryl-aldehyde oxidase activity
+property_value: skos:exactMatch EC:1.2.3.14
+property_value: skos:exactMatch RHEA:20529
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010294
@@ -103870,6 +108200,8 @@
xref: MetaCyc:RXN-8155
xref: RHEA:31031
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch RHEA:31031
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010295
@@ -103886,6 +108218,9 @@
xref: MetaCyc:1.14.13.93-RXN
xref: RHEA:12897
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.137
+property_value: skos:exactMatch RHEA:12897
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010296
@@ -103895,6 +108230,8 @@
xref: MetaCyc:RXN-8409
xref: RHEA:48520
is_a: GO:0051723 ! protein methylesterase activity
+property_value: skos:exactMatch RHEA:48520
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010297
@@ -103912,6 +108249,8 @@
xref: MetaCyc:RXN-8275
xref: RHEA:34807
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch RHEA:34807
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010299
@@ -103936,7 +108275,10 @@
xref: MetaCyc:1.1.1.288-RXN
xref: RHEA:12548
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.288
+property_value: skos:exactMatch RHEA:12548
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010303
@@ -103949,7 +108291,9 @@
xref: EC:3.2.1.142
xref: MetaCyc:3.2.1.142-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.142
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010304
@@ -103997,6 +108341,9 @@
xref: MetaCyc:R146-RXN
xref: RHEA:14161
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.53
+property_value: skos:exactMatch RHEA:14161
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010309
@@ -104018,6 +108365,9 @@
xref: Reactome:R-HSA-1237119 "Acireductone is oxidized to MOB"
xref: RHEA:24504
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.54
+property_value: skos:exactMatch RHEA:24504
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010310
@@ -104194,7 +108544,10 @@
xref: MetaCyc:R15-RXN
xref: RHEA:31763
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.88
+property_value: skos:exactMatch RHEA:31763
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010327
@@ -104257,6 +108610,7 @@
namespace: molecular_function
def: "Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units." [GOC:tair_curators]
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:broadMatch EC:4.2.3.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -104380,6 +108734,8 @@
xref: MetaCyc:RXNQT-4142
xref: RHEA:26349
is_a: GO:0070456 ! galactose-1-phosphate phosphatase activity
+property_value: skos:exactMatch RHEA:26349
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010348
@@ -104399,7 +108755,10 @@
xref: MetaCyc:RXN-1884
xref: RHEA:31559
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.316
+property_value: skos:exactMatch RHEA:31559
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21831" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/3975" xsd:anyURI
[Term]
@@ -104442,6 +108801,7 @@
namespace: molecular_function
def: "Catalysis of the transfer of a prenyl group from one compound (donor) to homogentisic acid." [PMID:16989822]
is_a: GO:0004659 ! prenyltransferase activity
+property_value: skos:broadMatch EC:2.5.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
[Term]
@@ -104462,8 +108822,11 @@
xref: MetaCyc:RXN-14929
xref: RHEA:38003
is_a: GO:0010354 ! homogentisate prenyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.116
+property_value: skos:exactMatch RHEA:38003
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26832" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010357
@@ -104476,9 +108839,12 @@
xref: MetaCyc:RXN-2761
xref: RHEA:37995
is_a: GO:0010354 ! homogentisate prenyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.117
+property_value: skos:exactMatch RHEA:37995
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26829" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26832" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010358
@@ -105061,8 +109427,11 @@
xref: RHEA:44452
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
relationship: part_of GO:0006744 ! ubiquinone biosynthetic process
+property_value: skos:exactMatch EC:2.1.1.114
+property_value: skos:exactMatch RHEA:44452
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26632" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29420" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sl
creation_date: 2015-10-28T22:12:58Z
@@ -105557,6 +109926,9 @@
xref: MetaCyc:RXN4FS-12
xref: RHEA:65708
is_a: GO:0070568 ! guanylyltransferase activity
+property_value: skos:broadMatch EC:2.7.7.69
+property_value: skos:exactMatch RHEA:65708
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010472
@@ -105568,6 +109940,9 @@
xref: MetaCyc:RXN4FS-13
xref: RHEA:65712
is_a: GO:0070568 ! guanylyltransferase activity
+property_value: skos:broadMatch EC:2.7.7.69
+property_value: skos:exactMatch RHEA:65712
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010473
@@ -105653,6 +110028,7 @@
synonym: "H3 histone acetylase activity" EXACT []
synonym: "H3 histone acetyltransferase activity" EXACT []
is_a: GO:0004402 ! histone acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -105664,6 +110040,7 @@
synonym: "H4 histone acetylase activity" EXACT []
synonym: "H4 histone acetyltransferase activity" EXACT []
is_a: GO:0004402 ! histone acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -105685,6 +110062,9 @@
xref: MetaCyc:RXN-11190
xref: RHEA:30515
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.79
+property_value: skos:exactMatch RHEA:30515
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0010488
@@ -105787,7 +110167,6 @@
synonym: "proteasome-mediated protein catabolic process" EXACT []
synonym: "proteasome-mediated protein catabolism" EXACT []
is_a: GO:0030163 ! protein catabolic process
-is_a: GO:0051603 ! proteolysis involved in protein catabolic process
[Term]
id: GO:0010499
@@ -105960,8 +110339,8 @@
subset: gocheck_obsoletion_candidate
is_a: GO:0051336 ! regulation of hydrolase activity
intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0004620 ! phospholipase activity
-relationship: regulates GO:0004620 ! phospholipase activity
+intersection_of: regulates GO:0004620 ! glycerophospholipase activity
+relationship: regulates GO:0004620 ! glycerophospholipase activity
[Term]
id: GO:0010518
@@ -105972,8 +110351,8 @@
is_a: GO:0010517 ! regulation of phospholipase activity
is_a: GO:0060193 ! positive regulation of lipase activity
intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0004620 ! phospholipase activity
-relationship: positively_regulates GO:0004620 ! phospholipase activity
+intersection_of: positively_regulates GO:0004620 ! glycerophospholipase activity
+relationship: positively_regulates GO:0004620 ! glycerophospholipase activity
[Term]
id: GO:0010519
@@ -106153,9 +110532,6 @@
synonym: "Hsp27 protein regulator activity" EXACT []
is_obsolete: true
replaced_by: GO:0051008
-consider: GO:0006457
-consider: GO:0051082
-consider: GO:0051787
[Term]
id: GO:0010539
@@ -106166,9 +110542,6 @@
synonym: "Hsp27 protein inhibitor activity" EXACT []
is_obsolete: true
replaced_by: GO:0051008
-consider: GO:0006457
-consider: GO:0051082
-consider: GO:0051787
[Term]
id: GO:0010540
@@ -106223,9 +110596,6 @@
synonym: "Hsp90 protein regulator activity" EXACT []
is_obsolete: true
replaced_by: GO:0051879
-consider: GO:0006457
-consider: GO:0051082
-consider: GO:0051787
[Term]
id: GO:0010546
@@ -106236,9 +110606,6 @@
synonym: "Hsp90 protein inhibitor activity" EXACT []
is_obsolete: true
replaced_by: GO:0051879
-consider: GO:0006457
-consider: GO:0051082
-consider: GO:0051787
[Term]
id: GO:0010547
@@ -108954,7 +113321,6 @@
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P." [GOC:BHF, GOC:rl]
is_a: GO:0010813 ! neuropeptide catabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0010815
@@ -108962,7 +113328,6 @@
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin." [GOC:BHF, GOC:rl]
is_a: GO:0009056 ! catabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0010816
@@ -108970,7 +113335,6 @@
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin." [GOC:BHF, GOC:rl]
is_a: GO:0042447 ! hormone catabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0010817
@@ -110319,6 +114683,7 @@
def: "Catalysis of the reaction: NADPH + H2O = NMNH + ADP." [GOC:tb, PMID:12790796, RHEA:60820]
xref: RHEA:60820
is_a: GO:0004551 ! dinucleotide phosphatase activity
+property_value: skos:exactMatch RHEA:60820
[Term]
id: GO:0010944
@@ -110335,10 +114700,18 @@
synonym: "CoA diphosphatase activity" RELATED []
synonym: "CoA pyrophosphatase activity" RELATED []
synonym: "coenzyme A pyrophosphatase activity" RELATED []
+xref: EC:3.6.1.77
+xref: MetaCyc:RXN-10811
xref: Reactome:R-HSA-6809354 "NUDT7 hydrolyses CoA-SH to 3',5'-ADP and PPANT"
xref: Reactome:R-HSA-6810474 "NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT"
xref: Reactome:R-HSA-9837354 "NUDT8 hydrolyzes CoA-SH to PPANT"
+xref: RHEA:50044
+xref: RHEA:64988
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:narrowMatch EC:3.6.1.77
+property_value: skos:narrowMatch MetaCyc:RXN-10811
+property_value: skos:narrowMatch RHEA:50044
+property_value: skos:narrowMatch RHEA:64988
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24569" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28938" xsd:anyURI
@@ -112145,15 +116518,15 @@
[Term]
id: GO:0014716
-name: skeletal muscle satellite stem cell asymmetric division involved in skeletal muscle regeneration
+name: obsolete skeletal muscle satellite stem cell asymmetric division involved in skeletal muscle regeneration
namespace: biological_process
-def: "Skeletal muscle satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt." [GOC:mtg_muscle]
-comment: Occurrence of this process outside of the context of muscle repair is probably very rare, so there is a good case for merging this with the parent class.
+def: "OBSOLETE. Skeletal muscle satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt." [GOC:mtg_muscle]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "satellite cell asymmetric division involved in skeletal muscle regeneration" EXACT []
-is_a: GO:0014833 ! skeletal muscle satellite stem cell asymmetric division
-intersection_of: GO:0014833 ! skeletal muscle satellite stem cell asymmetric division
-intersection_of: part_of GO:0043403 ! skeletal muscle tissue regeneration
-relationship: part_of GO:0014834 ! skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0014833
+consider: GO:0043403
[Term]
id: GO:0014717
@@ -112775,23 +117148,25 @@
[Term]
id: GO:0014837
-name: myoblast fate determination involved in skeletal muscle regeneration
+name: obsolete myoblast fate determination involved in skeletal muscle regeneration
namespace: biological_process
-def: "The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle, PMID:16607119]
-is_a: GO:0007518 ! myoblast fate determination
-intersection_of: GO:0007518 ! myoblast fate determination
-intersection_of: part_of GO:0043403 ! skeletal muscle tissue regeneration
-relationship: part_of GO:0014836 ! myoblast fate commitment involved in skeletal muscle regeneration
+def: "OBSOLETE. The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle, PMID:16607119]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007518
+consider: GO:0043403
[Term]
id: GO:0014838
-name: myoblast fate specification involved in skeletal muscle regeneration
+name: obsolete myoblast fate specification involved in skeletal muscle regeneration
namespace: biological_process
-def: "The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle, PMID:16607119]
-is_a: GO:0048626 ! myoblast fate specification
-intersection_of: GO:0048626 ! myoblast fate specification
-intersection_of: part_of GO:0043403 ! skeletal muscle tissue regeneration
-relationship: part_of GO:0014836 ! myoblast fate commitment involved in skeletal muscle regeneration
+def: "OBSOLETE. The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle, PMID:16607119]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0043403
+consider: GO:0048626
[Term]
id: GO:0014839
@@ -113016,10 +117391,12 @@
[Term]
id: GO:0014868
-name: cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction
+name: obsolete cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction
namespace: biological_process
-def: "A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction." [GOC:mtg_muscle]
-is_a: GO:0014880 ! regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction
+def: "OBSOLETE. A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction." [GOC:mtg_muscle]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0014869
@@ -113038,10 +117415,12 @@
[Term]
id: GO:0014871
-name: cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction
+name: obsolete cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction
namespace: biological_process
-def: "The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction." [GOC:mtg_muscle]
-is_a: GO:0014880 ! regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction
+def: "OBSOLETE. The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction." [GOC:mtg_muscle]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0014872
@@ -113075,14 +117454,15 @@
[Term]
id: GO:0014875
-name: detection of muscle activity involved in regulation of muscle adaptation
+name: obsolete detection of muscle activity involved in regulation of muscle adaptation
namespace: biological_process
-def: "The series of events by which a muscle activity stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle]
+def: "OBSOLETE. The series of events by which a muscle activity stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "detection of fatigue" EXACT []
-is_a: GO:0014864 ! detection of muscle activity
-is_a: GO:0014873 ! response to muscle activity involved in regulation of muscle adaptation
-intersection_of: GO:0014864 ! detection of muscle activity
-intersection_of: part_of GO:0043502 ! regulation of muscle adaptation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0014864
+consider: GO:0043502
[Term]
id: GO:0014876
@@ -113116,13 +117496,14 @@
[Term]
id: GO:0014879
-name: detection of electrical stimulus involved in regulation of muscle adaptation
+name: obsolete detection of electrical stimulus involved in regulation of muscle adaptation
namespace: biological_process
-def: "The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle]
-is_a: GO:0014878 ! response to electrical stimulus involved in regulation of muscle adaptation
-is_a: GO:0050981 ! detection of electrical stimulus
-intersection_of: GO:0050981 ! detection of electrical stimulus
-intersection_of: part_of GO:0043502 ! regulation of muscle adaptation
+def: "OBSOLETE. The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0043502
+consider: GO:0050981
[Term]
id: GO:0014880
@@ -113162,24 +117543,26 @@
[Term]
id: GO:0014884
-name: detection of muscle inactivity involved in regulation of muscle adaptation
+name: obsolete detection of muscle inactivity involved in regulation of muscle adaptation
namespace: biological_process
-def: "The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle]
-is_a: GO:0014869 ! detection of muscle inactivity
-is_a: GO:0014877 ! response to muscle inactivity involved in regulation of muscle adaptation
-intersection_of: GO:0014869 ! detection of muscle inactivity
-intersection_of: part_of GO:0043502 ! regulation of muscle adaptation
+def: "OBSOLETE. The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0014869
+consider: GO:0043502
[Term]
id: GO:0014885
-name: detection of injury involved in regulation of muscle adaptation
+name: obsolete detection of injury involved in regulation of muscle adaptation
namespace: biological_process
-def: "The series of events by which an injury stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle]
+def: "OBSOLETE. The series of events by which an injury stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "detection of injury involved in regulation of muscle plasticity" RELATED []
-is_a: GO:0014822 ! detection of wounding
-is_a: GO:0014876 ! response to injury involved in regulation of muscle adaptation
-intersection_of: GO:0014822 ! detection of wounding
-intersection_of: part_of GO:0043502 ! regulation of muscle adaptation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0014822
+consider: GO:0043502
[Term]
id: GO:0014886
@@ -113234,10 +117617,12 @@
[Term]
id: GO:0014893
-name: response to rest involved in regulation of muscle adaptation
+name: obsolete response to rest involved in regulation of muscle adaptation
namespace: biological_process
-def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation." [GOC:mtg_muscle]
-is_a: GO:0014877 ! response to muscle inactivity involved in regulation of muscle adaptation
+def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation." [GOC:mtg_muscle]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0014894
@@ -113389,18 +117774,21 @@
[Term]
id: GO:0014914
-name: myoblast maturation involved in muscle regeneration
+name: obsolete myoblast maturation involved in muscle regeneration
namespace: biological_process
-def: "A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:mtg_muscle]
-is_a: GO:0048628 ! myoblast maturation
+def: "OBSOLETE. A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:mtg_muscle]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0014915
-name: regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction
+name: obsolete regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction
namespace: biological_process
-def: "Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction." [GOC:dph, GOC:mtg_muscle, GOC:tb]
-is_a: GO:0014880 ! regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction
-is_a: GO:0032972 ! regulation of muscle filament sliding speed
+def: "OBSOLETE. Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction." [GOC:dph, GOC:mtg_muscle, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0014916
@@ -113653,8 +118041,11 @@
xref: Reactome:R-HSA-2022860 "NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS)"
xref: RHEA:21980
is_a: GO:0034483 ! heparan sulfate sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.8
+property_value: skos:exactMatch RHEA:21980
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28380" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28762" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015017
@@ -113678,9 +118069,13 @@
xref: MetaCyc:2.4.1.135-RXN
xref: Reactome:R-HSA-1889955 "B3GAT dimers transfer GlcA to tetrasaccharide linker"
xref: Reactome:R-HSA-3560802 "Defective B3GAT3 does not transfer GlcA to tetrasaccharide linker"
+xref: Reactome:R-HSA-9638064 "B3GAT3 dimer transfers GlcA to tetrasaccharide linker"
xref: RHEA:24168
is_a: GO:0015020 ! glucuronosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.135
+property_value: skos:exactMatch RHEA:24168
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28907" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015019
@@ -113698,6 +118093,9 @@
xref: Reactome:R-HSA-9036056 "Defective HGSNAT does not acetylate Heparan sulfate chain(3)"
xref: RHEA:15125
is_a: GO:0008080 ! N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.78
+property_value: skos:exactMatch MetaCyc:2.3.1.78-RXN
+property_value: skos:exactMatch RHEA:15125
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29323" xsd:anyURI
[Term]
@@ -113772,13 +118170,13 @@
xref: Reactome:R-HSA-2162099 "abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP"
xref: Reactome:R-HSA-5604954 "Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BIL"
xref: Reactome:R-HSA-5604975 "Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BIL"
-xref: Reactome:R-HSA-5617143 "B4GAT1:LARGE transfers initial GlcA to matriglycan chain"
+xref: Reactome:R-HSA-5617143 "B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA"
xref: Reactome:R-HSA-8941701 "UGT1A10 transfers GlcA from UDP-GlcA to GCTN"
xref: Reactome:R-HSA-9036102 "Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BMG"
xref: Reactome:R-HSA-9036104 "Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BMG"
xref: Reactome:R-HSA-9632038 "UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG"
xref: Reactome:R-HSA-9632039 "UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG"
-xref: Reactome:R-HSA-9638097 "LARGE1,2 elongates matriglycan chain with GlcA"
+xref: Reactome:R-HSA-9638097 "B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA"
xref: Reactome:R-HSA-9749977 "UGT1A6 glucuronates ST"
xref: Reactome:R-HSA-9756134 "UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL"
xref: Reactome:R-HSA-9756156 "UGT1A3 lactonizes ATV to ATVL"
@@ -113787,7 +118185,10 @@
xref: RHEA:21032
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.17
+property_value: skos:exactMatch RHEA:21032
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28907" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015021
@@ -113803,6 +118204,8 @@
xref: EC:4.2.2.8
xref: MetaCyc:4.2.2.8-RXN
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.8
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015023
@@ -113825,6 +118228,8 @@
xref: EC:3.1.6.18
xref: MetaCyc:3.1.6.18-RXN
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.18
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015025
@@ -113877,9 +118282,9 @@
subset: goslim_pir
subset: goslim_yeast
synonym: "enzyme transport" NARROW []
+is_a: GO:0006810 ! transport
is_a: GO:0008104 ! intracellular protein localization
is_a: GO:0045184 ! establishment of protein localization
-is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0015032
@@ -114003,7 +118408,10 @@
xref: RHEA:16757
is_a: GO:0015036 ! disulfide oxidoreductase activity
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:exactMatch EC:1.8.1.12
+property_value: skos:exactMatch RHEA:16757
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015043
@@ -114015,7 +118423,12 @@
synonym: "NAD(P)H:ferrileghemoglobin oxidoreductase activity" RELATED [EC:1.6.2.6]
xref: EC:1.6.2.6
xref: MetaCyc:LEGHEMOGLOBIN-REDUCTASE-RXN
+xref: RHEA:16157
+xref: RHEA:16161
is_a: GO:0016653 ! oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
+property_value: skos:exactMatch EC:1.6.2.6
+property_value: skos:narrowMatch RHEA:16157
+property_value: skos:narrowMatch RHEA:16161
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29675" xsd:anyURI
[Term]
@@ -114037,6 +118450,8 @@
xref: MetaCyc:RUBREDOXIN--NAD+-REDUCTASE-RXN
xref: RHEA:18597
is_a: GO:0015045 ! rubredoxin-NAD(P)H reductase activity
+property_value: skos:exactMatch EC:1.18.1.1
+property_value: skos:exactMatch RHEA:18597
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29598" xsd:anyURI
[Term]
@@ -114054,7 +118469,9 @@
xref: EC:1.18.1.4
xref: MetaCyc:RUBREDOXIN--NADP+-REDUCTASE-RXN
is_a: GO:0016731 ! oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.18.1.4
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015046
@@ -114063,8 +118480,10 @@
def: "Catalysis of the reaction: 2 reduced [rubredoxin] + NADP+ + H+ = 2 oxidized [rubredoxin] + NADPH." [RHEA:13949]
xref: RHEA:13949
is_a: GO:0015045 ! rubredoxin-NAD(P)H reductase activity
+property_value: skos:exactMatch RHEA:13949
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29598" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015047
@@ -114078,6 +118497,9 @@
xref: MetaCyc:NADPH--CYTOCHROME-C2-REDUCTASE-RXN
xref: RHEA:15237
is_a: GO:0016653 ! oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
+property_value: skos:exactMatch EC:1.6.2.5
+property_value: skos:exactMatch RHEA:15237
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015048
@@ -114096,9 +118518,19 @@
synonym: "methane hydroxylase activity" RELATED [EC:1.14.13.25]
synonym: "methane,NAD(P)H:oxygen oxidoreductase (hydroxylating)" RELATED [EC:1.14.13.25]
xref: EC:1.14.13.25
+xref: KEGG_REACTION:R01142
+xref: KEGG_REACTION:R01143
xref: MetaCyc:METHANE-MONOOXYGENASE-RXN
+xref: RHEA:13637
+xref: RHEA:13641
xref: UM-BBD_enzymeID:r0237
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.25
+property_value: skos:exactMatch MetaCyc:METHANE-MONOOXYGENASE-RXN
+property_value: skos:narrowMatch KEGG_REACTION:R01142
+property_value: skos:narrowMatch KEGG_REACTION:R01143
+property_value: skos:narrowMatch RHEA:13637
+property_value: skos:narrowMatch RHEA:13641
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -114282,6 +118714,8 @@
synonym: "transamidinase activity" EXACT []
xref: EC:2.1.4.-
is_a: GO:0016741 ! transferase activity, transferring one-carbon groups
+property_value: skos:exactMatch EC:2.1.4.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015068
@@ -114297,6 +118731,9 @@
xref: Reactome:R-HSA-71275 "arginine + glycine => ornithine + guanidoacetate"
xref: RHEA:13201
is_a: GO:0015067 ! amidinotransferase activity
+property_value: skos:exactMatch EC:2.1.4.1
+property_value: skos:exactMatch RHEA:13201
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015069
@@ -114313,6 +118750,9 @@
xref: MetaCyc:2.1.4.2-RXN
xref: RHEA:13265
is_a: GO:0015067 ! amidinotransferase activity
+property_value: skos:exactMatch EC:2.1.4.2
+property_value: skos:exactMatch RHEA:13265
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015070
@@ -114520,8 +118960,6 @@
xref: Reactome:R-HSA-1362417 "Mitoferrin translocates iron from the mitochondrial intermembrane space to the mitochondrial matrix"
xref: Reactome:R-HSA-442368 "SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region"
xref: Reactome:R-HSA-5655760 "Defective SLC40A1 does not transport Fe3+ from extracellular region to cytosol"
-xref: Reactome:R-HSA-9911596 "FeoAB transports Fe2+ from periplasmic space to the cytosol"
-xref: Reactome:R-HSA-9911598 "EfeUOB transport Fe2+ from periplasmic space to the cytosol"
is_a: GO:0005381 ! iron ion transmembrane transporter activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
@@ -114708,7 +119146,7 @@
namespace: molecular_function
def: "Enables the transfer of iodide ions from one side of a membrane to the other." [GOC:ai]
xref: Reactome:R-HSA-209910 "Iodide is taken up by thyroid epithelial cells"
-xref: Reactome:R-HSA-5627802 "SLC26A4 exports I- to follicular lumen"
+xref: Reactome:R-HSA-5627802 "SLC26A4 transports I- from cytosol to extracellular region"
xref: Reactome:R-HSA-5627870 "SLC26A4 does not transport I- from cytosol to extracellular region"
is_a: GO:0008509 ! monoatomic anion transmembrane transporter activity
relationship: part_of GO:0015705 ! iodide transport
@@ -114763,9 +119201,8 @@
synonym: "sulfate permease activity" RELATED []
synonym: "sulphate transporter activity" EXACT []
xref: Reactome:R-HSA-3560789 "Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol"
-xref: Reactome:R-HSA-427555 "SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol"
+xref: Reactome:R-HSA-427555 "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol"
xref: Reactome:R-HSA-8875871 "SLC26A11 transports SO4(2-) from extracellular region to cytosol"
-xref: Reactome:R-HSA-9941470 "SLC26A11 imports SO4(2-) and H+ into cytosol"
is_a: GO:1901682 ! sulfur compound transmembrane transporter activity
relationship: part_of GO:1902358 ! sulfate transmembrane transport
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
@@ -114825,7 +119262,6 @@
name: allantoate transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of allantoate from one side of a membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen." [GOC:ai, ISBN:0198547684]
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
relationship: part_of GO:0015719 ! allantoate transport
@@ -114940,7 +119376,6 @@
name: glucuronate transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of glucuronate from one side of a membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group." [GOC:ai]
-xref: Reactome:R-HSA-2162229 "SLC17A5 exports GlcA from the lysosome to the cytosol"
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
relationship: part_of GO:0015738 ! glucuronate transmembrane transport
@@ -115170,8 +119605,6 @@
name: polysaccharide transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
-xref: Reactome:R-HSA-9932121 "Unknown transporter exports CA to extracellular space"
-xref: Reactome:R-HSA-9932466 "Bcs complex exports pEtN-cellulose"
is_a: GO:0015144 ! carbohydrate transmembrane transporter activity
is_a: GO:0022884 ! macromolecule transmembrane transporter activity
relationship: part_of GO:0015774 ! polysaccharide transport
@@ -115196,6 +119629,7 @@
xref: TC:2.A.66.2.3
is_a: GO:0140328 ! floppase activity
relationship: part_of GO:0015776 ! capsular polysaccharide transport
+property_value: skos:broadMatch RHEA:66132
[Term]
id: GO:0015164
@@ -115274,6 +119708,7 @@
synonym: "hydroxy/aromatic amino acid permease activity" RELATED []
xref: Reactome:R-HSA-210439 "glutamate uptake by astrocytes"
xref: Reactome:R-HSA-212642 "L-Glutamine transport into neurons"
+xref: Reactome:R-HSA-351963 "SLC6A18 transports Gly from extracellular region to cytosol"
xref: Reactome:R-HSA-351987 "SLC6A6-mediated uptake of taurine and beta-alanine"
xref: Reactome:R-HSA-352029 "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine"
xref: Reactome:R-HSA-352052 "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol"
@@ -115287,6 +119722,7 @@
xref: Reactome:R-HSA-352174 "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine"
xref: Reactome:R-HSA-352182 "SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine"
xref: Reactome:R-HSA-352191 "SLC7A8-mediated uptake of neutral amino acids"
+xref: Reactome:R-HSA-352232 "SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol"
xref: Reactome:R-HSA-352347 "SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine"
xref: Reactome:R-HSA-352354 "SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine"
xref: Reactome:R-HSA-352364 "SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine"
@@ -115310,6 +119746,7 @@
xref: Reactome:R-HSA-5655702 "Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu"
xref: Reactome:R-HSA-5659674 "Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol"
xref: Reactome:R-HSA-5659734 "Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol"
+xref: Reactome:R-HSA-5659755 "Defective SLC6A18 does not transport Gly from extracellular region to cytosol"
xref: Reactome:R-HSA-5660694 "Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol"
xref: Reactome:R-HSA-5660890 "Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu"
xref: Reactome:R-HSA-5660910 "Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane"
@@ -115381,7 +119818,6 @@
def: "Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids." [GOC:ai, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0815340729]
synonym: "L-amino acid transporter activity" BROAD []
xref: Reactome:R-HSA-212614 "Glutamine transport from astrocytes"
-xref: Reactome:R-HSA-352232 "SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol"
is_a: GO:0015171 ! amino acid transmembrane transporter activity
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
relationship: part_of GO:1902475 ! L-alpha-amino acid transmembrane transport
@@ -115405,7 +119841,6 @@
synonym: "L-asparagine transporter activity" BROAD []
is_a: GO:0015175 ! neutral L-amino acid transmembrane transporter activity
is_a: GO:0015179 ! L-amino acid transmembrane transporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
relationship: part_of GO:0006867 ! asparagine transport
[Term]
@@ -115554,6 +119989,7 @@
synonym: "L-serine transporter activity" BROAD []
synonym: "serine transporter activity" BROAD []
synonym: "threonine/serine:sodium symporter activity" RELATED []
+xref: Reactome:R-HSA-8932980 "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane"
is_a: GO:0015179 ! L-amino acid transmembrane transporter activity
relationship: part_of GO:0015825 ! L-serine transport
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
@@ -115623,7 +120059,7 @@
def: "Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2." [ISBN:0198506732]
synonym: "urea transporter activity" BROAD []
xref: Reactome:R-HSA-444126 "HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively"
-is_a: GO:0042887 ! amide transmembrane transporter activity
+is_a: GO:0022857 ! transmembrane transporter activity
relationship: part_of GO:0071918 ! urea transmembrane transport
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
@@ -115736,7 +120172,6 @@
name: pyrimidine nucleotide transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other." [GOC:ai]
-xref: Reactome:R-HSA-9940804 "SLC35A1,4 import CDP-ribitol"
is_a: GO:0015215 ! nucleotide transmembrane transporter activity
relationship: part_of GO:0006864 ! pyrimidine nucleotide transport
@@ -115807,7 +120242,6 @@
synonym: "vitamin H transporter activity" RELATED []
xref: MetaCyc:TRANS-RXN0-240
is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:0090482 ! vitamin transmembrane transporter activity
is_a: GO:1901682 ! sulfur compound transmembrane transporter activity
relationship: part_of GO:0015878 ! biotin transport
@@ -115849,7 +120283,6 @@
xref: Reactome:R-HSA-9837333 "SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP"
is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity
is_a: GO:0015932 ! nucleobase-containing compound transmembrane transporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:1901682 ! sulfur compound transmembrane transporter activity
relationship: part_of GO:0035349 ! coenzyme A transmembrane transport
@@ -115901,8 +120334,6 @@
xref: Reactome:R-HSA-917870 "SLC46A1 transports hemes from extracellular region to cytosol"
xref: Reactome:R-HSA-917892 "FLVCR1-1 transports heme from cytosol to extracellular region"
xref: Reactome:R-HSA-9661408 "FLVCR1-2 transports heme from mitochondrial matrix to cytosol"
-xref: Reactome:R-HSA-9927224 "ChuA imports heme to periplasm"
-xref: Reactome:R-HSA-9927930 "DppBCDF transports heme to cytosol"
is_a: GO:0022857 ! transmembrane transporter activity
relationship: part_of GO:0015886 ! heme transport
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19472" xsd:anyURI
@@ -115914,7 +120345,6 @@
def: "Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods." [GOC:ai, ISBN:0721662544]
synonym: "pantothenate transporter activity" BROAD [GOC:mah]
synonym: "vitamin B5 transmembrane transporter activity" EXACT []
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
is_a: GO:0072349 ! modified amino acid transmembrane transporter activity
is_a: GO:0090482 ! vitamin transmembrane transporter activity
@@ -115957,7 +120387,6 @@
def: "Enables the transfer of cycloheximide from one side of a membrane to the other. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes." [ISBN:0198506732]
synonym: "cycloheximide transporter activity" RELATED []
is_a: GO:0015665 ! alcohol transmembrane transporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
relationship: part_of GO:0015901 ! cycloheximide transport
[Term]
@@ -115998,6 +120427,7 @@
is_a: GO:0005548 ! phospholipid transporter activity
is_a: GO:0140327 ! flippase activity
relationship: part_of GO:0140331 ! aminophospholipid translocation
+property_value: skos:broadMatch RHEA:66132
[Term]
id: GO:0015248
@@ -116027,6 +120457,7 @@
xref: Reactome:R-HSA-507870 "Aquaporins passively transport water out of cells"
is_a: GO:0005372 ! water transmembrane transporter activity
is_a: GO:0015267 ! channel activity
+property_value: skos:broadMatch RHEA:29667
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
@@ -116039,6 +120470,7 @@
xref: Reactome:R-HSA-9729542 "OTOP1 transports H+ from the extracellular region to the cytosol"
is_a: GO:0005261 ! monoatomic cation channel activity
is_a: GO:0015078 ! proton transmembrane transporter activity
+property_value: skos:broadMatch RHEA:34979
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
[Term]
@@ -116064,6 +120496,7 @@
xref: Reactome:R-HSA-507871 "Aquaporins passively transport glycerol out of cells"
is_a: GO:0015168 ! glycerol transmembrane transporter activity
is_a: GO:0015267 ! channel activity
+property_value: skos:broadMatch RHEA:29675
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
@@ -116149,7 +120582,7 @@
is_obsolete: true
consider: GO:0005275
consider: GO:0015203
-consider: GO:0042887
+consider: GO:0022857
[Term]
id: GO:0015264
@@ -116168,6 +120601,7 @@
xref: Reactome:R-HSA-507875 "Aquaporins passively transport urea into cells"
is_a: GO:0015204 ! urea transmembrane transporter activity
is_a: GO:0015267 ! channel activity
+property_value: skos:broadMatch RHEA:32799
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
[Term]
@@ -116187,9 +120621,6 @@
synonym: "substrate-specific channel activity" RELATED []
xref: Reactome:R-HSA-3779381 "H2O2 diffuses from the mitochondrial matrix to the cytosol"
xref: Reactome:R-HSA-8953430 "PXMP2 trimer transports glycolate from cytosol to peroxisomal matrix"
-xref: Reactome:R-HSA-9857649 "p-S373-GJA1:p-S-ITGA5:ITGB1 (p-S373-Connexin-43:p-S-Integrin alpha5:Integrin beta1) transports ATP from the cytosol to the extracellular region"
-xref: Reactome:R-HSA-9857682 "p-S373-GJA1:p-S-ITGA5:ITGB1 (p-S373-Connexin-43:p-S-Integrin alpha5:Integrin beta1) transports prostaglandin E2 (PGE2) from the cytosol to the extracellular region"
-xref: Reactome:R-HSA-9905999 "Pannexin1 (PANX1) channel in a complex with P2RX7 transports ATP from the cytosol to the extracellular region"
xref: TC:1
is_a: GO:0022803 ! passive transmembrane transporter activity
@@ -116322,6 +120753,7 @@
def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in)." [TC:2.A.1.1.13]
is_a: GO:0005353 ! fructose transmembrane transporter activity
is_a: GO:0008516 ! hexose uniporter activity
+property_value: skos:broadMatch RHEA:60372
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
[Term]
@@ -116331,11 +120763,6 @@
def: "Enables the transfer of substances, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport, ISBN:0815340729, PMID:10839820, TC:1.B.1.-.-]
synonym: "outer membrane exporter porin" NARROW []
synonym: "porin" EXACT []
-xref: Reactome:R-HSA-9760573 "TolC complex exports STa"
-xref: Reactome:R-HSA-9911510 "MacA:MacB:TolC transports azithromycin from the periplasm to the extracellular region"
-xref: Reactome:R-HSA-9911516 "AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region"
-xref: Reactome:R-HSA-9914083 "MdtE:MdtF:TolC exports beta-lactams to extracellular space"
-xref: Reactome:R-HSA-9926021 "HlyB:HlyD:TolC transports HlyA from periplasm to extracellular space"
xref: Wikipedia:Porin_(protein)
is_a: GO:0022829 ! wide pore channel activity
@@ -116507,6 +120934,7 @@
synonym: "glucose uniporter activity" EXACT []
is_a: GO:0008516 ! hexose uniporter activity
is_a: GO:0055056 ! D-glucose transmembrane transporter activity
+property_value: skos:broadMatch RHEA:60376
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
[Term]
@@ -116534,7 +120962,6 @@
synonym: "sialate:cation symporter activity" BROAD []
is_a: GO:0015136 ! sialic acid transmembrane transporter activity
is_a: GO:0015294 ! solute:monoatomic cation symporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI
@@ -116576,7 +121003,6 @@
synonym: "benomyl:hydrogen antiporter activity" EXACT []
is_a: GO:0015078 ! proton transmembrane transporter activity
is_a: GO:0015297 ! antiporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
[Term]
id: GO:0015311
@@ -116774,10 +121200,14 @@
namespace: molecular_function
def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in), up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement." [GOC:mtg_transport, TC:2.A.17.-.-]
synonym: "peptide:hydrogen symporter activity" EXACT []
+xref: MetaCyc:RXN-14653
xref: Reactome:R-HSA-427998 "SLC25A1 transports di-/tri-peptides and peptide-like drugs"
xref: Reactome:R-HSA-428007 "Proton-coupled histidine and di-peptide cotransport"
+xref: RHEA:37047
is_a: GO:0015295 ! solute:proton symporter activity
is_a: GO:1904680 ! peptide transmembrane transporter activity
+property_value: skos:narrowMatch MetaCyc:RXN-14653
+property_value: skos:narrowMatch RHEA:37047
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
[Term]
@@ -116880,12 +121310,25 @@
synonym: "siderophore transporter activity" RELATED []
synonym: "siderophore-iron transporter activity" RELATED []
xref: Reactome:R-HSA-1222597 "Loaded mycobactin gets imported"
-xref: Reactome:R-HSA-9911605 "FyuA transports Ybt:Fe/Cu from extracellular space to the periplasm"
-xref: Reactome:R-HSA-9928256 "YbtPQ transports Ybt:Fe/Cu to the cytosol"
-xref: Reactome:R-HSA-9930902 "IutA imports FeAer to the periplasm"
-xref: Reactome:R-HSA-9930911 "FhuBCD imports FeAer to the cytosol"
-xref: Reactome:R-HSA-9931043 "FecA:TonB:ExbB:ExbD imports Fe3+-citrates to periplasm"
+xref: TC:2.A.1.16.1
+xref: TC:2.A.1.16.2
+xref: TC:2.A.1.16.3
+xref: TC:2.A.1.16.4
+xref: TC:2.A.1.16.5
+xref: TC:2.A.1.16.6
+xref: TC:2.A.1.16.7
+xref: TC:2.A.1.16.8
+xref: TC:2.A.1.16.9
is_a: GO:0015603 ! iron chelate transmembrane transporter activity
+property_value: skos:narrowMatch TC:2.A.1.16.1
+property_value: skos:narrowMatch TC:2.A.1.16.2
+property_value: skos:narrowMatch TC:2.A.1.16.3
+property_value: skos:narrowMatch TC:2.A.1.16.4
+property_value: skos:narrowMatch TC:2.A.1.16.5
+property_value: skos:narrowMatch TC:2.A.1.16.6
+property_value: skos:narrowMatch TC:2.A.1.16.7
+property_value: skos:narrowMatch TC:2.A.1.16.8
+property_value: skos:narrowMatch TC:2.A.1.16.9
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23199" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23485" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29742" xsd:anyURI
@@ -116929,7 +121372,7 @@
comment: The reason for obsoletion is that this term was an unnecessary and confusing grouping term.
xref: Reactome:R-HSA-561059 "OAT2 and OAT4 mediate transport of sulphate conjugates"
xref: Reactome:R-HSA-879562 "SLCO2B1 has a narrow substrate specificity"
-xref: Reactome:R-HSA-879584 "SLCO3A1 isoform 1 has a broad substrate specificity"
+xref: Reactome:R-HSA-879584 "SLCO3A1 isoform 1 has abroad substrate specificity"
xref: Reactome:R-HSA-879594 "SLCO4C1 mediates the transport of digoxin"
xref: Reactome:R-HSA-9661397 "SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte)"
xref: Reactome:R-HSA-9661446 "BMG, BDG translocates from ER lumen to cytosol"
@@ -116970,7 +121413,6 @@
def: "Enables the transfer of methotrexate, 4-amino-10-methylformic acid from one side of a membrane to the other. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase." [GOC:ai]
synonym: "methotrexate transporter activity" RELATED []
is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:0042910 ! xenobiotic transmembrane transporter activity
relationship: part_of GO:0051958 ! methotrexate transport
@@ -117091,8 +121533,12 @@
synonym: "L-malic acid:proton symporter activity" RELATED [GOC:vw]
synonym: "malate permease" RELATED [GOC:vw]
synonym: "malate:hydrogen symporter activity" EXACT []
+xref: RHEA:28715
+xref: RHEA:29339
is_a: GO:0015140 ! malate transmembrane transporter activity
is_a: GO:0015295 ! solute:proton symporter activity
+property_value: skos:narrowMatch RHEA:28715
+property_value: skos:narrowMatch RHEA:29339
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
[Term]
@@ -117103,9 +121549,11 @@
synonym: "2-oxoglutarate/malate carrier protein" EXACT [Wikipedia:Mitochondrial_carrier]
xref: Reactome:R-HSA-198440 "SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane"
xref: Reactome:R-HSA-376851 "SLC25A11 exchanges 2-OG and MAL"
+xref: RHEA:71587
is_a: GO:0015139 ! alpha-ketoglutarate transmembrane transporter activity
is_a: GO:0015140 ! malate transmembrane transporter activity
is_a: GO:0015297 ! antiporter activity
+property_value: skos:narrowMatch RHEA:71587
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
[Term]
@@ -117128,6 +121576,8 @@
xref: RHEA:71799
is_a: GO:0015368 ! calcium:monoatomic cation antiporter activity
is_a: GO:0051139 ! metal cation:proton antiporter activity
+property_value: skos:exactMatch RHEA:71799
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015370
@@ -117191,7 +121641,9 @@
is_a: GO:0005295 ! neutral L-amino acid:sodium symporter activity
is_a: GO:0005343 ! organic acid:sodium symporter activity
is_a: GO:0015187 ! glycine transmembrane transporter activity
+property_value: skos:exactMatch RHEA:68228
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015376
@@ -117241,7 +121693,9 @@
xref: TC:2.A.30.1.5
is_a: GO:0015079 ! potassium ion transmembrane transporter activity
is_a: GO:0015377 ! chloride:monoatomic cation symporter activity
+property_value: skos:exactMatch RHEA:72427
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015381
@@ -117302,7 +121756,9 @@
xref: RHEA:29251
is_a: GO:0015081 ! sodium ion transmembrane transporter activity
is_a: GO:0051139 ! metal cation:proton antiporter activity
+property_value: skos:exactMatch RHEA:29251
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015386
@@ -117314,7 +121770,9 @@
xref: RHEA:29467
is_a: GO:0022821 ! solute:potassium antiporter activity
is_a: GO:0051139 ! metal cation:proton antiporter activity
+property_value: skos:exactMatch RHEA:29467
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015387
@@ -117326,7 +121784,9 @@
xref: RHEA:28490
is_a: GO:0015079 ! potassium ion transmembrane transporter activity
is_a: GO:0015295 ! solute:proton symporter activity
+property_value: skos:exactMatch RHEA:28490
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015389
@@ -117413,7 +121873,9 @@
xref: TC:3
is_a: GO:0022804 ! active transmembrane transporter activity
relationship: has_part GO:0003824 ! catalytic activity
+property_value: skos:exactMatch EC:7.-.-.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21274" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015400
@@ -117479,6 +121941,9 @@
is_a: GO:0015091 ! ferric iron transmembrane transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.2.2.7
+property_value: skos:exactMatch RHEA:12332
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015410
@@ -117498,6 +121963,9 @@
is_a: GO:0005384 ! manganese ion transmembrane transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.2.2.5
+property_value: skos:exactMatch RHEA:17365
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015411
@@ -117513,8 +121981,11 @@
xref: RHEA:14613
is_a: GO:0005368 ! taurine transmembrane transporter activity
is_a: GO:0042959 ! ABC-type alkanesulfonate transporter transporter activity
+property_value: skos:exactMatch EC:7.6.2.7
+property_value: skos:exactMatch RHEA:14613
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21640" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015412
@@ -117532,6 +122003,9 @@
xref: RHEA:22020
is_a: GO:0015098 ! molybdate ion transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.3.2.5
+property_value: skos:exactMatch RHEA:22020
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015413
@@ -117552,6 +122026,9 @@
is_a: GO:0015099 ! nickel cation transmembrane transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.2.2.11
+property_value: skos:exactMatch RHEA:15557
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015414
@@ -117568,6 +122045,9 @@
xref: RHEA:13181
is_a: GO:0015112 ! nitrate transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.3.2.4
+property_value: skos:exactMatch RHEA:13181
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015415
@@ -117586,7 +122066,10 @@
xref: RHEA:24440
is_a: GO:0005315 ! phosphate transmembrane transporter activity
is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity
+property_value: skos:exactMatch EC:7.3.2.1
+property_value: skos:exactMatch RHEA:24440
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015416
@@ -117612,7 +122095,10 @@
xref: RHEA:18065
is_a: GO:0140359 ! ABC-type transporter activity
relationship: part_of GO:0015716 ! organic phosphonate transport
+property_value: skos:exactMatch EC:7.3.2.2
+property_value: skos:exactMatch RHEA:18065
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015417
@@ -117631,9 +122117,15 @@
synonym: "spermidine-importing ATPase activity" NARROW []
xref: EC:7.6.2.11
xref: MetaCyc:3.6.3.31-RXN
+xref: MetaCyc:ABC-24-RXN
+xref: RHEA:29999
is_a: GO:0015203 ! polyamine transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.6.2.11
+property_value: skos:narrowMatch MetaCyc:ABC-24-RXN
+property_value: skos:narrowMatch RHEA:29999
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015418
@@ -117654,7 +122146,10 @@
xref: RHEA:11036
is_a: GO:0015651 ! quaternary ammonium group transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.6.2.9
+property_value: skos:exactMatch RHEA:11036
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015419
@@ -117671,6 +122166,8 @@
xref: RHEA:10192
is_a: GO:0015116 ! sulfate transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:broadMatch EC:7.3.2.3
+property_value: skos:exactMatch RHEA:10192
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
[Term]
@@ -117702,8 +122199,11 @@
is_a: GO:0090482 ! vitamin transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
relationship: part_of GO:0015889 ! cobalamin transport
+property_value: skos:exactMatch EC:7.6.2.8
+property_value: skos:exactMatch RHEA:17873
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21353" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015421
@@ -117722,7 +122222,10 @@
xref: RHEA:14429
is_a: GO:0035673 ! oligopeptide transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.4.2.6
+property_value: skos:exactMatch RHEA:14429
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015422
@@ -117739,6 +122242,8 @@
xref: MetaCyc:3.6.3.18-RXN
is_a: GO:0015157 ! oligosaccharide transmembrane transporter activity
is_a: GO:0043211 ! ABC-type carbohydrate transporter activity
+property_value: skos:exactMatch EC:7.5.2.2
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015423
@@ -117757,7 +122262,10 @@
is_a: GO:0005363 ! maltose transmembrane transporter activity
is_a: GO:0015422 ! ABC-type oligosaccharide transporter activity
relationship: part_of GO:1904981 ! maltose transmembrane transport
+property_value: skos:exactMatch EC:7.5.2.1
+property_value: skos:exactMatch RHEA:22132
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015424
@@ -117790,6 +122298,8 @@
xref: MetaCyc:3.6.3.22-RXN
xref: TC:3.A.1.4.1
is_a: GO:0015424 ! ABC-type amino acid transporter activity
+property_value: skos:exactMatch EC:7.4.2.2
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015426
@@ -117811,6 +122321,9 @@
xref: MetaCyc:3.6.3.21-RXN
xref: RHEA:14673
is_a: GO:0015424 ! ABC-type amino acid transporter activity
+property_value: skos:exactMatch EC:7.4.2.1
+property_value: skos:exactMatch RHEA:14673
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015427
@@ -117862,7 +122375,10 @@
xref: RHEA:21668
is_a: GO:0015169 ! glycerol-3-phosphate transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.6.2.10
+property_value: skos:exactMatch RHEA:21668
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17164" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015431
@@ -117882,7 +122398,10 @@
xref: RHEA:19121
is_a: GO:0140359 ! ABC-type transporter activity
is_a: GO:1901682 ! sulfur compound transmembrane transporter activity
+property_value: skos:exactMatch EC:7.6.2.3
+property_value: skos:exactMatch RHEA:19121
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
created_by: mah
creation_date: 2010-10-25T02:32:02Z
@@ -117905,6 +122424,8 @@
is_a: GO:0033285 ! ATPase-coupled monocarboxylic acid transmembrane transporter activity
is_a: GO:0034040 ! ATPase-coupled lipid transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch RHEA:50048
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
@@ -117925,7 +122446,10 @@
xref: RHEA:65972
xref: TC:3.A.1.209.1
is_a: GO:0015440 ! ABC-type peptide transporter activity
+property_value: skos:exactMatch EC:7.4.2.14
+property_value: skos:exactMatch RHEA:65972
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015434
@@ -117941,6 +122465,8 @@
is_a: GO:0015086 ! cadmium ion transmembrane transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.2.2.2
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015435
@@ -117968,6 +122494,8 @@
is_a: GO:0033284 ! ATPase-coupled carboxylic acid transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
relationship: part_of GO:0015776 ! capsular polysaccharide transport
+property_value: skos:exactMatch EC:7.6.2.12
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015437
@@ -117981,6 +122509,7 @@
synonym: "LPS-transporting ATPase activity" EXACT []
is_a: GO:0140328 ! floppase activity
relationship: part_of GO:0015920 ! lipopolysaccharide transport
+property_value: skos:broadMatch RHEA:66132
[Term]
id: GO:0015438
@@ -118000,6 +122529,8 @@
is_a: GO:0140359 ! ABC-type transporter activity
is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity
relationship: part_of GO:0015777 ! teichoic acid transport
+property_value: skos:exactMatch EC:7.5.2.4
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015439
@@ -118024,7 +122555,10 @@
is_a: GO:0015232 ! heme transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
relationship: part_of GO:0035351 ! heme transmembrane transport
+property_value: skos:exactMatch EC:7.6.2.5
+property_value: skos:exactMatch RHEA:19261
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015440
@@ -118038,6 +122572,7 @@
is_a: GO:0140359 ! ABC-type transporter activity
is_a: GO:1904680 ! peptide transmembrane transporter activity
relationship: part_of GO:0015833 ! peptide transport
+property_value: skos:broadMatch EC:7.4.2.5
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
[Term]
@@ -118055,6 +122590,9 @@
xref: RHEA:18453
is_a: GO:0015160 ! beta-glucan transmembrane transporter activity
is_a: GO:0043211 ! ABC-type carbohydrate transporter activity
+property_value: skos:exactMatch EC:7.5.2.3
+property_value: skos:exactMatch RHEA:18453
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015442
@@ -118096,6 +122634,9 @@
is_a: GO:0015095 ! magnesium ion transmembrane transporter activity
is_a: GO:0015662 ! P-type ion transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
+property_value: skos:exactMatch EC:7.2.2.14
+property_value: skos:exactMatch RHEA:10260
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015445
@@ -118113,6 +122654,9 @@
is_a: GO:0015080 ! silver ion transmembrane transporter activity
is_a: GO:0015662 ! P-type ion transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
+property_value: skos:exactMatch EC:7.2.2.15
+property_value: skos:exactMatch RHEA:14733
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015446
@@ -118135,6 +122679,9 @@
is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity
is_a: GO:1901683 ! arsenate ion transmembrane transporter activity
relationship: part_of GO:0071722 ! detoxification of arsenic-containing substance
+property_value: skos:exactMatch EC:7.3.2.7
+property_value: skos:exactMatch RHEA:11348
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015447
@@ -118181,11 +122728,19 @@
namespace: molecular_function
def: "Primary active transport of a solute across a membrane driven by decarboxylation of a cytoplasmic substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source." [GOC:mtg_transport, ISBN:0815340729, TC:3.B.-.-.-]
synonym: "decarboxylation-driven transporter" EXACT []
+xref: EC:7.2.4.1
+xref: EC:7.2.4.2
+xref: EC:7.2.4.3
+xref: EC:7.2.4.4
xref: TC:3.B
is_a: GO:0015399 ! primary active transmembrane transporter activity
intersection_of: GO:0015399 ! primary active transmembrane transporter activity
intersection_of: has_part GO:0016831 ! carboxy-lyase activity
relationship: has_part GO:0016831 ! carboxy-lyase activity
+property_value: skos:narrowMatch EC:7.2.4.1
+property_value: skos:narrowMatch EC:7.2.4.2
+property_value: skos:narrowMatch EC:7.2.4.3
+property_value: skos:narrowMatch EC:7.2.4.4
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -118260,6 +122815,7 @@
synonym: "protein-transporting ATPase activity" BROAD []
is_a: GO:0015450 ! protein-transporting ATPase activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:broadMatch EC:7.4.2.5
[Term]
id: GO:0015464
@@ -118450,6 +123006,7 @@
xref: Wikipedia:Maltoporin
is_a: GO:0005363 ! maltose transmembrane transporter activity
is_a: GO:0015288 ! porin activity
+property_value: skos:broadMatch RHEA:33171
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
[Term]
@@ -118588,7 +123145,9 @@
is_a: GO:0005280 ! amino acid:proton symporter activity
is_a: GO:0015185 ! gamma-aminobutyric acid transmembrane transporter activity
is_a: GO:0015355 ! secondary active monocarboxylate transmembrane transporter activity
+property_value: skos:exactMatch RHEA:28915
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015496
@@ -118608,7 +123167,6 @@
namespace: molecular_function
def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in)." [TC:2.A.21.1.1]
is_a: GO:0005343 ! organic acid:sodium symporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
is_a: GO:0072349 ! modified amino acid transmembrane transporter activity
relationship: part_of GO:0098719 ! sodium ion import across plasma membrane
@@ -118652,7 +123210,9 @@
is_a: GO:0005283 ! amino acid:sodium symporter activity
is_a: GO:0005343 ! organic acid:sodium symporter activity
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
+property_value: skos:exactMatch RHEA:29031
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015503
@@ -118735,7 +123295,9 @@
is_a: GO:0015141 ! succinate transmembrane transporter activity
is_a: GO:0015297 ! antiporter activity
is_a: GO:0071913 ! citrate secondary active transmembrane transporter activity
+property_value: skos:exactMatch RHEA:28835
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015516
@@ -118889,6 +123451,8 @@
xref: RHEA:32123
is_a: GO:0015295 ! solute:proton symporter activity
is_a: GO:0071913 ! citrate secondary active transmembrane transporter activity
+property_value: skos:exactMatch RHEA:32123
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015532
@@ -118937,7 +123501,9 @@
xref: RHEA:29023
is_a: GO:0009679 ! hexose:proton symporter activity
is_a: GO:0015150 ! fucose transmembrane transporter activity
+property_value: skos:exactMatch RHEA:29023
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015537
@@ -118962,7 +123528,9 @@
xref: RHEA:28987
is_a: GO:0015136 ! sialic acid transmembrane transporter activity
is_a: GO:0015295 ! solute:proton symporter activity
+property_value: skos:exactMatch RHEA:28987
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015539
@@ -119032,7 +123600,6 @@
def: "Enables the transfer of sulfathiazole from one side of a membrane to the other. Sulfathiazole is an antibacterial agent of the sulfonamide group." [GOC:curators]
synonym: "bicyclomycin/sulfathiazole:hydrogen antiporter activity" RELATED []
synonym: "sulphathiazole transporter activity" EXACT []
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:1901474 ! azole transmembrane transporter activity
is_a: GO:1901682 ! sulfur compound transmembrane transporter activity
relationship: part_of GO:1902599 ! sulfathiazole transmembrane transport
@@ -119228,13 +123795,14 @@
name: N-acetylglucosamine transmembrane transporter activity
namespace: molecular_function
alt_id: GO:0015580
-def: "Enables the transfer of N-acetylglucosamine from one side of a membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein." [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
+def: "Enables the transfer of N-acetylglucosamine from one side of a membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein." [GOC:ai, GOC:mtg_transport, ISBN:0815340729, PMID:41075780]
synonym: "D-GlcNAc transmembrane transporter activity" EXACT []
synonym: "N-Acetyl-D-glucosamine permease" RELATED []
synonym: "N-acetyl-D-glucosamine transmembrane transporter activity" EXACT []
synonym: "N-acetylchitosamine transmembrane transporter activity" EXACT []
synonym: "N-acetylglucosamine permease activity" RELATED []
is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30986" xsd:anyURI
[Term]
id: GO:0015573
@@ -119355,7 +123923,10 @@
xref: RHEA:29995
is_a: GO:0015417 ! ABC-type polyamine transporter activity
is_a: GO:0015489 ! putrescine transmembrane transporter activity
+property_value: skos:exactMatch EC:7.6.2.16
+property_value: skos:exactMatch RHEA:29995
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
@@ -119398,6 +123969,8 @@
is_a: GO:0015186 ! L-glutamine transmembrane transporter activity
is_a: GO:0015426 ! ATPase-coupled polar amino acid-transporter activity
is_a: GO:0033284 ! ATPase-coupled carboxylic acid transmembrane transporter activity
+property_value: skos:exactMatch RHEA:29895
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
@@ -119442,7 +124015,6 @@
name: iron chelate transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of an iron chelate from one side of a membrane to the other. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions." [PMID:17660286]
-xref: Reactome:R-HSA-9931048 "FecBCDE imports Fe3+-citrates to cytosol"
is_a: GO:0022857 ! transmembrane transporter activity
relationship: part_of GO:0033214 ! siderophore-iron import into cell
@@ -119480,11 +124052,13 @@
is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity
is_a: GO:0015932 ! nucleobase-containing compound transmembrane transporter activity
is_a: GO:0034040 ! ATPase-coupled lipid transmembrane transporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
is_a: GO:1901682 ! sulfur compound transmembrane transporter activity
relationship: part_of GO:0015916 ! fatty-acyl-CoA transport
+property_value: skos:exactMatch EC:7.6.2.4
+property_value: skos:exactMatch RHEA:15181
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015608
@@ -119509,6 +124083,9 @@
xref: RHEA:29903
is_a: GO:0015407 ! ABC-type monosaccharide transporter activity
is_a: GO:0015591 ! D-ribose transmembrane transporter activity
+property_value: skos:exactMatch EC:7.5.2.7
+property_value: skos:exactMatch RHEA:29903
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015612
@@ -119522,6 +124099,10 @@
xref: RHEA:30007
is_a: GO:0015147 ! L-arabinose transmembrane transporter activity
is_a: GO:0015407 ! ABC-type monosaccharide transporter activity
+property_value: skos:broadMatch EC:7.5.2.13
+property_value: skos:exactMatch EC:7.5.2.12
+property_value: skos:exactMatch MetaCyc:ABC-2-RXN
+property_value: skos:exactMatch RHEA:30007
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
[Term]
@@ -119549,6 +124130,10 @@
xref: RHEA:29899
is_a: GO:0015148 ! D-xylose transmembrane transporter activity
is_a: GO:0015407 ! ABC-type monosaccharide transporter activity
+property_value: skos:broadMatch EC:7.5.2.13
+property_value: skos:exactMatch EC:7.5.2.10
+property_value: skos:exactMatch MetaCyc:ABC-33-RXN
+property_value: skos:exactMatch RHEA:29899
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
@@ -119564,6 +124149,9 @@
is_a: GO:0015149 ! hexose transmembrane transporter activity
is_a: GO:0015407 ! ABC-type monosaccharide transporter activity
relationship: part_of GO:0015754 ! D-allose transmembrane transport
+property_value: skos:exactMatch EC:7.5.2.8
+property_value: skos:exactMatch RHEA:29799
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015616
@@ -119590,8 +124178,6 @@
name: ferric-enterobactin transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of ferric-enterobactin from one side of a membrane to the other." [GOC:ai]
-xref: Reactome:R-HSA-9911602 "FepA:TonB:ExbB:ExbD transports ferrienterobactin from the extracellular region to the periplasmic space"
-xref: Reactome:R-HSA-9911603 "FepC:FepD:FepG transports ferrienterobactin from the periplasmic space to the cytosol"
is_a: GO:0015343 ! siderophore-iron transmembrane transporter activity
relationship: part_of GO:0015685 ! ferric-enterobactin import into cell
@@ -119617,6 +124203,9 @@
xref: RHEA:58492
is_a: GO:0015603 ! iron chelate transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.2.2.17
+property_value: skos:exactMatch RHEA:58492
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015625
@@ -119640,8 +124229,10 @@
xref: MetaCyc:ABC-11-RXN
is_a: GO:0015603 ! iron chelate transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.2.2.16
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17164" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015626
@@ -119718,7 +124309,10 @@
is_a: GO:0005385 ! zinc ion transmembrane transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.2.2.20
+property_value: skos:exactMatch RHEA:29795
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015634
@@ -119749,7 +124343,6 @@
namespace: molecular_function
def: "Enables the transfer of a microcin from one side of a membrane to the other." [GOC:mah]
synonym: "microcin uptake permease activity" EXACT []
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:0042910 ! xenobiotic transmembrane transporter activity
relationship: part_of GO:0042884 ! microcin transport
@@ -119844,8 +124437,10 @@
is_a: GO:0015145 ! monosaccharide transmembrane transporter activity
is_a: GO:0015355 ! secondary active monocarboxylate transmembrane transporter activity
relationship: part_of GO:0046411 ! 2-keto-3-deoxygluconate transmembrane transport
+property_value: skos:exactMatch RHEA:29943
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015650
@@ -119913,7 +124508,9 @@
is_a: GO:0005283 ! amino acid:sodium symporter activity
is_a: GO:0005343 ! organic acid:sodium symporter activity
is_a: GO:0022858 ! alanine transmembrane transporter activity
+property_value: skos:exactMatch RHEA:29283
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-08-08T12:57:30Z
@@ -119988,12 +124585,6 @@
name: alcohol transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group." [ISBN:0198506732]
-xref: Reactome:R-HSA-192010 "5beta-cholestan-3alpha, 7alpha, 12alpha-triol is translocated from the cytosol to the mitochondrial matrix"
-xref: Reactome:R-HSA-193537 "5beta-cholestan-3alpha, 7alpha-diol is translocated from the cytosol to the mitochondrial matrix"
-xref: Reactome:R-HSA-193715 "5beta-cholestan-3alpha,7alpha,24(S)-triol is translocated from the cytosol to the mitochondrial matrix"
-xref: Reactome:R-HSA-193774 "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is translocated from the cytosol to the mitochondrial matrix"
-xref: Reactome:R-HSA-193808 "5beta-cholestan-3alpha,7alpha,27-triol is translocated from the cytosol to the mitochondrial matrix"
-xref: Reactome:R-HSA-193832 "5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is translocated from the cytosol to the mitochondrial matrix"
is_a: GO:0022857 ! transmembrane transporter activity
[Term]
@@ -120025,6 +124616,9 @@
xref: RHEA:16857
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
is_a: GO:0009008 ! DNA-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.113
+property_value: skos:exactMatch RHEA:16857
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015668
@@ -120036,6 +124630,8 @@
xref: MetaCyc:3.1.21.5-RXN
is_a: GO:0015666 ! restriction endodeoxyribonuclease activity
is_a: GO:0016888 ! DNA endonuclease activity, producing 5'-phosphomonoesters
+property_value: skos:exactMatch EC:3.1.21.5
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0015669
@@ -120112,7 +124708,6 @@
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29105" xsd:anyURI
is_obsolete: true
replaced_by: GO:0051604
-consider: GO:0016531
[Term]
id: GO:0015685
@@ -120401,7 +124996,7 @@
def: "The directed movement of allantoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc]
synonym: "allantoin/allantoate transport" BROAD []
is_a: GO:0015718 ! monocarboxylic acid transport
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0015720
@@ -120410,7 +125005,7 @@
def: "The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "allantoin transmembrane transport" EXACT [GOC:mah]
synonym: "allantoin/allantoate transport" BROAD []
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0015721
@@ -121331,7 +125926,7 @@
namespace: biological_process
def: "The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
subset: goslim_pir
-is_a: GO:0042886 ! amide transport
+is_a: GO:0006810 ! transport
[Term]
id: GO:0015834
@@ -121393,7 +125988,7 @@
namespace: biological_process
def: "The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2." [GOC:ai, ISBN:0198506732]
is_a: GO:0019755 ! one-carbon compound transport
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0015841
@@ -121683,8 +126278,8 @@
synonym: "vitamin B7 transport" EXACT []
synonym: "vitamin H transport" EXACT []
is_a: GO:0015718 ! monocarboxylic acid transport
-is_a: GO:0042886 ! amide transport
is_a: GO:0051180 ! vitamin transport
+is_a: GO:0071705 ! nitrogen compound transport
is_a: GO:0072348 ! sulfur compound transport
[Term]
@@ -121704,7 +126299,6 @@
is_a: GO:0015711 ! organic anion transport
is_a: GO:0015748 ! organophosphate ester transport
is_a: GO:0015931 ! nucleobase-containing compound transport
-is_a: GO:0042886 ! amide transport
is_a: GO:0072348 ! sulfur compound transport
[Term]
@@ -121751,7 +126345,6 @@
synonym: "vitamin B9 transport" EXACT []
synonym: "vitamin M transport" EXACT []
is_a: GO:0006835 ! dicarboxylic acid transport
-is_a: GO:0042886 ! amide transport
is_a: GO:0051180 ! vitamin transport
is_a: GO:0072337 ! modified amino acid transport
@@ -121783,7 +126376,6 @@
synonym: "vitamin B5 transport" EXACT []
is_a: GO:0015718 ! monocarboxylic acid transport
is_a: GO:0035461 ! vitamin transmembrane transport
-is_a: GO:0042886 ! amide transport
is_a: GO:0072337 ! modified amino acid transport
is_a: GO:1905039 ! carboxylic acid transmembrane transport
@@ -121898,7 +126490,7 @@
namespace: biological_process
def: "The directed movement of cycloheximide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes." [ISBN:0198506732]
is_a: GO:0015850 ! organic hydroxy compound transport
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0015902
@@ -122034,7 +126626,6 @@
is_a: GO:0015711 ! organic anion transport
is_a: GO:0015748 ! organophosphate ester transport
is_a: GO:0015931 ! nucleobase-containing compound transport
-is_a: GO:0042886 ! amide transport
is_a: GO:1901337 ! thioester transport
[Term]
@@ -122143,6 +126734,7 @@
namespace: molecular_function
def: "Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors." [GOC:curators]
is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors
+property_value: skos:broadMatch EC:1.4.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28942" xsd:anyURI
[Term]
@@ -122201,7 +126793,6 @@
synonym: "coenzyme A metabolism" EXACT []
is_a: GO:0006753 ! nucleoside phosphate metabolic process
is_a: GO:0006790 ! sulfur compound metabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0072521 ! purine-containing compound metabolic process
[Term]
@@ -122215,12 +126806,25 @@
synonym: "coenzyme A biosynthesis" EXACT []
synonym: "coenzyme A formation" EXACT []
synonym: "coenzyme A synthesis" EXACT []
+xref: MetaCyc:COA-PWY
+xref: MetaCyc:COA-PWY-1
+xref: MetaCyc:PANTOSYN-PWY
+xref: MetaCyc:PWY-4221
+xref: MetaCyc:PWY-7851
+xref: MetaCyc:PWY-8342
+xref: MetaCyc:PWY8J2-29
xref: Reactome:R-HSA-196783 "Coenzyme A biosynthesis"
is_a: GO:0015936 ! coenzyme A metabolic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0044272 ! sulfur compound biosynthetic process
is_a: GO:0072522 ! purine-containing compound biosynthetic process
is_a: GO:1901293 ! nucleoside phosphate biosynthetic process
+property_value: skos:narrowMatch MetaCyc:COA-PWY
+property_value: skos:narrowMatch MetaCyc:COA-PWY-1
+property_value: skos:narrowMatch MetaCyc:PANTOSYN-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-4221
+property_value: skos:narrowMatch MetaCyc:PWY-7851
+property_value: skos:narrowMatch MetaCyc:PWY-8342
+property_value: skos:narrowMatch MetaCyc:PWY8J2-29
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -122250,7 +126854,6 @@
xref: Reactome:R-HSA-199220 "Vitamin B5 (pantothenate) metabolism"
is_a: GO:0006575 ! modified amino acid metabolic process
is_a: GO:0032787 ! monocarboxylic acid metabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0015940
@@ -122276,11 +126879,16 @@
synonym: "pantothenate synthesis from valine" NARROW []
synonym: "vitamin B5 biosynthesis" EXACT []
synonym: "vitamin B5 biosynthetic process" EXACT []
+xref: MetaCyc:PANTO-PWY
+xref: MetaCyc:PWY-3961
+xref: MetaCyc:PWY-6654
is_a: GO:0015939 ! pantothenate metabolic process
is_a: GO:0042364 ! water-soluble vitamin biosynthetic process
is_a: GO:0042398 ! modified amino acid biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0072330 ! monocarboxylic acid biosynthetic process
+property_value: skos:narrowMatch MetaCyc:PANTO-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-3961
+property_value: skos:narrowMatch MetaCyc:PWY-6654
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -122862,7 +127470,7 @@
def: "Binds to and increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid." [GOC:ai]
xref: Reactome:R-HSA-400023 "Gq alpha activates Phospholipase C beta"
is_a: GO:0060229 ! lipase activator activity
-relationship: positively_regulates GO:0004620 ! phospholipase activity
+relationship: positively_regulates GO:0004620 ! glycerophospholipase activity
[Term]
id: GO:0016005
@@ -122870,7 +127478,7 @@
namespace: molecular_function
def: "Binds to and increases the activity of the enzyme phospholipase A2." [GOC:ai]
is_a: GO:0016004 ! phospholipase activator activity
-relationship: positively_regulates GO:0004623 ! phospholipase A2 activity
+relationship: positively_regulates GO:0004623 ! A2-type glycerophospholipase activity
[Term]
id: GO:0016006
@@ -122976,7 +127584,7 @@
namespace: molecular_function
def: "Binding to cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids." [GOC:mb]
synonym: "cyclophilin" RELATED []
-is_a: GO:0033218 ! amide binding
+is_a: GO:0005488 ! binding
[Term]
id: GO:0016019
@@ -123124,6 +127732,9 @@
xref: RHEA:14817
xref: UM-BBD_reactionID:r0106
is_a: GO:0016859 ! cis-trans isomerase activity
+property_value: skos:exactMatch EC:5.2.1.2
+property_value: skos:exactMatch RHEA:14817
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016035
@@ -123182,6 +127793,10 @@
xref: MetaCyc:GLUTAMATE-SYNTHASE-NADH-RXN
xref: RHEA:13753
is_a: GO:0015930 ! glutamate synthase activity
+property_value: skos:exactMatch EC:1.4.1.14
+property_value: skos:exactMatch MetaCyc:GLUTAMATE-SYNTHASE-NADH-RXN
+property_value: skos:exactMatch RHEA:13753
+property_value: skos:relatedMatch MetaCyc:GLUGLNSYN-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -123199,6 +127814,10 @@
xref: RHEA:12128
is_a: GO:0015930 ! glutamate synthase activity
is_a: GO:0016643 ! oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.4.7.1
+property_value: skos:exactMatch MetaCyc:GLUTAMATE-SYNTHASE-FERREDOXIN-RXN
+property_value: skos:exactMatch RHEA:12128
+property_value: skos:relatedMatch MetaCyc:PWY-4341
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -124194,8 +128813,12 @@
synonym: "brassinosteroid biosynthesis" EXACT []
synonym: "brassinosteroid formation" EXACT []
synonym: "brassinosteroid synthesis" EXACT []
+xref: MetaCyc:PWY-2582
+xref: MetaCyc:PWY-699
is_a: GO:0016129 ! phytosteroid biosynthetic process
is_a: GO:0016131 ! brassinosteroid metabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-2582
+property_value: skos:narrowMatch MetaCyc:PWY-699
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -124407,6 +129030,9 @@
xref: RHEA:23856
xref: UM-BBD_reactionID:r0406
is_a: GO:0016723 ! oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.16.1.1
+property_value: skos:exactMatch RHEA:23856
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016153
@@ -124420,9 +129046,12 @@
xref: EC:4.2.1.49
xref: KEGG_REACTION:R02914
xref: MetaCyc:UROCANATE-HYDRATASE-RXN
-xref: Reactome:R-HSA-70903 "urocanate + H2O => 4-imidazolone-5-propanoate"
+xref: Reactome:R-HSA-70903 "urocanate + H2O => 4-imidazolone-5-propionate"
xref: RHEA:13101
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.49
+property_value: skos:exactMatch RHEA:13101
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016154
@@ -124433,6 +129062,8 @@
synonym: "pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity" RELATED [EC:2.4.2.2]
xref: EC:2.4.2.2
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.2
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016155
@@ -124450,6 +129081,9 @@
xref: MetaCyc:FORMYLTETRAHYDROFOLATE-DEHYDROGENASE-RXN
xref: RHEA:10180
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.6
+property_value: skos:exactMatch RHEA:10180
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016156
@@ -124463,8 +129097,11 @@
xref: RHEA:18281
is_a: GO:0000104 ! succinate dehydrogenase activity
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.6
+property_value: skos:exactMatch RHEA:18281
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17091" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27915" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016157
@@ -124482,6 +129119,8 @@
xref: MetaCyc:SUCROSE-SYNTHASE-RXN
xref: RHEA:16241
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.13
+property_value: skos:exactMatch RHEA:16241
[Term]
id: GO:0016158
@@ -124497,9 +129136,11 @@
synonym: "phytate 3-phosphatase activity" EXACT []
xref: EC:3.1.3.8
xref: MetaCyc:RXN0-1001
-xref: Reactome:R-HSA-1855225 "IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen"
xref: RHEA:16989
is_a: GO:0004446 ! inositol hexakisphosphate phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.62
+property_value: skos:exactMatch EC:3.1.3.8
+property_value: skos:exactMatch RHEA:16989
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25949" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30385" xsd:anyURI
@@ -124515,7 +129156,10 @@
xref: MetaCyc:MUCONOLACTONE-DELTA-ISOMERASE-RXN
xref: RHEA:12348
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.4
+property_value: skos:exactMatch RHEA:12348
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21637" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016160
@@ -124534,8 +129178,12 @@
synonym: "glycogenase activity" BROAD [EC:3.2.1.2]
synonym: "saccharogen amylase activity" RELATED [EC:3.2.1.2]
xref: EC:3.2.1.2
+xref: MetaCyc:RXN-12279
xref: MetaCyc:RXN-1827
is_a: GO:0016160 ! amylase activity
+property_value: skos:exactMatch EC:3.2.1.2
+property_value: skos:exactMatch MetaCyc:RXN-1827
+property_value: skos:narrowMatch MetaCyc:RXN-12279
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -124562,6 +129210,8 @@
xref: EC:3.2.1.91
xref: MetaCyc:3.2.1.91-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.91
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016163
@@ -124573,11 +129223,17 @@
synonym: "reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing) activity" RELATED [EC:1.18.6.1]
synonym: "vanadium-iron nitrogenase activity" NARROW []
xref: EC:1.18.6.1
+xref: EC:1.18.6.2
xref: MetaCyc:NITROGENASE-RXN
xref: RHEA:21448
+xref: UM-BBD_reactionID:r0600
xref: UM-BBD_reactionID:r1810
is_a: GO:0016732 ! oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor
relationship: part_of GO:0009399 ! nitrogen fixation
+property_value: skos:exactMatch EC:1.18.6.1
+property_value: skos:exactMatch RHEA:21448
+property_value: skos:narrowMatch EC:1.18.6.2
+property_value: skos:narrowMatch UM-BBD_reactionID:r0600
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27215" xsd:anyURI
[Term]
@@ -124608,6 +129264,9 @@
xref: MetaCyc:LIPOXYGENASE-RXN
xref: RHEA:22780
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.12
+property_value: skos:exactMatch RHEA:22780
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016166
@@ -124695,9 +129354,14 @@
synonym: "thyroid oxidase 2 activity" NARROW [EC:1.6.3.1]
synonym: "thyroid oxidase activity" NARROW [EC:1.6.3.1]
xref: EC:1.6.3.1
-xref: Reactome:R-HSA-5693681 "DUOX1 reduces O2 to H2O2"
+xref: Reactome:R-HSA-5693681 "DUOX1,2 reduce O2 to H2O2"
xref: Reactome:R-HSA-9698758 "FLT3 ITD- and NOX4-dependent H2O2 production"
+xref: RHEA:11260
+xref: RHEA:11264
is_a: GO:0050664 ! oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
+property_value: skos:exactMatch EC:1.6.3.1
+property_value: skos:narrowMatch RHEA:11260
+property_value: skos:narrowMatch RHEA:11264
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -124938,6 +129602,9 @@
xref: MetaCyc:RXN-11061
xref: RHEA:26341
is_a: GO:0051995 ! Se-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.280
+property_value: skos:exactMatch RHEA:26341
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016206
@@ -124958,6 +129625,9 @@
xref: RHEA:17877
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.6
+property_value: skos:exactMatch RHEA:17877
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016207
@@ -124990,6 +129660,9 @@
xref: RHEA:19641
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.12
+property_value: skos:exactMatch RHEA:19641
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016208
@@ -124997,8 +129670,6 @@
namespace: molecular_function
def: "Binding to AMP, adenosine monophosphate." [GOC:go_curators]
xref: Reactome:R-HSA-380930 "Phosphorylated AMPK binds AMP"
-xref: Reactome:R-HSA-453342 "PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex"
-xref: Reactome:R-HSA-453356 "PYGB dimer, b form + 2 AMP => PYGB b dimer:AMP complex"
is_a: GO:0032559 ! adenyl ribonucleotide binding
is_a: GO:0043168 ! anion binding
is_a: GO:0043169 ! cation binding
@@ -125031,7 +129702,10 @@
xref: MetaCyc:NARINGENIN-CHALCONE-SYNTHASE-RXN
xref: RHEA:11128
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.74
+property_value: skos:exactMatch RHEA:11128
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016211
@@ -125054,10 +129728,19 @@
synonym: "L-kynurenine aminotransferase activity" RELATED [EC:2.6.1.7]
synonym: "L-kynurenine:2-oxoglutarate aminotransferase activity" RELATED [EC:2.6.1.7]
xref: EC:2.6.1.7
+xref: MetaCyc:RXN-21858
+xref: MetaCyc:RXN-21859
xref: Reactome:R-HSA-893583 "kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate"
-xref: Reactome:R-HSA-893596 "PXLP-KYAT1 dimer transaminates L-KYN to KYNA"
-xref: Reactome:R-HSA-901097 "PXLP-KYAT3 (CCBL2) dimer transaminates L-KYN to KYNA"
+xref: Reactome:R-HSA-893596 "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu"
+xref: Reactome:R-HSA-901097 "kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + alanine [CCBL2]"
+xref: RHEA:65560
+xref: RHEA:65884
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.7
+property_value: skos:narrowMatch MetaCyc:RXN-21858
+property_value: skos:narrowMatch MetaCyc:RXN-21859
+property_value: skos:narrowMatch RHEA:65560
+property_value: skos:narrowMatch RHEA:65884
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25811" xsd:anyURI
[Term]
@@ -125088,7 +129771,12 @@
xref: Reactome:R-HSA-2046096 "Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA"
xref: Reactome:R-HSA-2046097 "Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA"
xref: Reactome:R-HSA-2046099 "Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA"
+xref: RHEA:47140
+xref: RHEA:47144
is_a: GO:0016215 ! acyl-CoA desaturase activity
+property_value: skos:exactMatch EC:1.14.19.3
+property_value: skos:narrowMatch RHEA:47140
+property_value: skos:narrowMatch RHEA:47144
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21804" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29820" xsd:anyURI
@@ -125116,6 +129804,9 @@
xref: MetaCyc:1.21.3.1-RXN
xref: RHEA:22428
is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
+property_value: skos:exactMatch EC:1.21.3.1
+property_value: skos:exactMatch RHEA:22428
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016217
@@ -125123,7 +129814,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: deethylsimazine + H2O = N-ethylammeline + chloride + H+." [MetaCyc:R465-RXN]
xref: MetaCyc:R465-RXN
-is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds
+is_a: GO:0019120 ! hydrolase activity, acting on halide bonds, in C-halide compounds
[Term]
id: GO:0016218
@@ -125162,6 +129853,8 @@
xref: Reactome:R-HSA-909776 "beta-alanine + pyruvate => 3-oxopropanoate + alanine"
xref: RHEA:14077
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.18
+property_value: skos:exactMatch RHEA:14077
[Term]
id: GO:0016226
@@ -125191,8 +129884,7 @@
synonym: "tRNA sulfurtransferase activity" EXACT []
synonym: "tRNA sulphurtransferase activity" EXACT []
is_obsolete: true
-replaced_by: GO:0034227
-consider: GO:0016783
+replaced_by: GO:0140741
[Term]
id: GO:0016229
@@ -125200,6 +129892,7 @@
namespace: molecular_function
def: "Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative." [GOC:mah]
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:broadMatch EC:1.-.-.-
[Term]
id: GO:0016230
@@ -125207,7 +129900,7 @@
namespace: molecular_function
def: "Binds to and increases the activity of the enzyme sphingomyelin phosphodiesterase." [GOC:ai]
synonym: "neutral sphingomyelinase activator" EXACT []
-is_a: GO:0016004 ! phospholipase activator activity
+is_a: GO:0060229 ! lipase activator activity
relationship: positively_regulates GO:0004767 ! sphingomyelin phosphodiesterase activity
[Term]
@@ -125216,6 +129909,7 @@
namespace: molecular_function
def: "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides." [PMID:29143882, PMID:37590576]
is_a: GO:0004563 ! beta-N-acetylhexosaminidase activity
+property_value: skos:broadMatch EC:3.2.1.52
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26013" xsd:anyURI
[Term]
@@ -125225,7 +129919,6 @@
def: "Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R)." [PMID:9478973]
synonym: "HNK-1 sulphotransferase activity" EXACT []
xref: Reactome:R-HSA-6786048 "CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1"
-xref: Reactome:R-HSA-9940718 "CHST10 sulfates matriglycan chain"
is_a: GO:0008146 ! sulfotransferase activity
[Term]
@@ -125378,7 +130071,10 @@
xref: Reactome:R-HSA-2263444 "Defective SGSH does not hydrolyse Heparan sulfate chain(7)"
xref: Reactome:R-HSA-9036050 "Defective SGSH does not hydrolyse Heparan sulfate chain(2)"
xref: RHEA:17881
-is_a: GO:0016826 ! hydrolase activity, acting on acid sulfur-nitrogen bonds
+is_a: GO:0016826 ! hydrolase activity, acting on sulfur-nitrogen bonds
+property_value: skos:exactMatch EC:3.10.1.1
+property_value: skos:exactMatch RHEA:17881
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016251
@@ -125472,15 +130168,17 @@
[Term]
id: GO:0016260
-name: selenocysteine biosynthetic process
+name: L-selenocysteine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins." [GOC:go_curators, ISBN:0198506732]
+def: "The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins." [GOC:go_curators, ISBN:0198506732, MetaCyc:Selenocysteine-Biosynthesis]
synonym: "selenocysteine anabolism" EXACT []
synonym: "selenocysteine biosynthesis" EXACT []
synonym: "selenocysteine formation" EXACT []
synonym: "selenocysteine synthesis" EXACT []
+xref: MetaCyc:Selenocysteine-Biosynthesis
is_a: GO:0009070 ! serine family amino acid biosynthetic process
is_a: GO:0016259 ! selenocysteine metabolic process
+property_value: skos:exactMatch MetaCyc:Selenocysteine-Biosynthesis
[Term]
id: GO:0016261
@@ -125510,23 +130208,31 @@
xref: RHEA:16533
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.4.1.94
+property_value: skos:exactMatch RHEA:16533
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016263
-name: glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity
+name: N-acetylgalactosaminide beta-1,3-galactosyltransferase activity
namespace: molecular_function
-def: "Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan." [EC:2.4.1.122, GOC:ma]
+def: "Catalysis of the reaction: an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + UDP + H+." [RHEA:15621]
synonym: "Core 1 GalT" RELATED []
+synonym: "glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity" EXACT [EC:2.4.1.122]
synonym: "UDP-galactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity" RELATED [EC:2.4.1.122]
synonym: "UDPgalactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity" RELATED [EC:2.4.1.122]
synonym: "uridine diphosphogalactose-mucin beta-(1->3)-galactosyltransferase activity" RELATED [EC:2.4.1.122]
xref: EC:2.4.1.122
-xref: MetaCyc:2.4.1.122-RXN
+xref: MetaCyc:RXN-18266
xref: Reactome:R-HSA-1964505 "C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens)"
xref: Reactome:R-HSA-6785524 "Defective C1GALT1C1 does not bind C1GALT1"
xref: RHEA:15621
+is_a: GO:0035250 ! UDP-galactosyltransferase activity
is_a: GO:0048531 ! beta-1,3-galactosyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.122
+property_value: skos:exactMatch RHEA:15621
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30971" xsd:anyURI
[Term]
id: GO:0016264
@@ -125556,8 +130262,12 @@
synonym: "mucin-type O-glycan synthesis" NARROW []
synonym: "O-glycan processing" EXACT []
synonym: "protein O-linked GalNAcylation" RELATED []
+xref: MetaCyc:PWY-7433
+xref: MetaCyc:PWY-7435
xref: Reactome:R-HSA-913709 "O-linked glycosylation of mucins"
is_a: GO:0006493 ! protein O-linked glycosylation
+property_value: skos:narrowMatch MetaCyc:PWY-7433
+property_value: skos:narrowMatch MetaCyc:PWY-7435
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27105" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30362" xsd:anyURI
@@ -125715,8 +130425,12 @@
xref: Reactome:R-HSA-8932413 "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1"
xref: Reactome:R-HSA-9844111 "EHMT1,EHMT2 trimethylates lysine-16 of ATF7IP"
xref: Reactome:R-HSA-9854315 "CSKMT methylates Citrate Synthase"
+xref: RHEA:51736
+xref: RHEA:54192
is_a: GO:0008276 ! protein methyltransferase activity
is_a: GO:0016278 ! lysine N-methyltransferase activity
+property_value: skos:narrowMatch RHEA:51736
+property_value: skos:narrowMatch RHEA:54192
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29483" xsd:anyURI
[Term]
@@ -125769,8 +130483,11 @@
synonym: "soluble alanyl aminopeptidase activity" RELATED [EC:3.4.11.14]
synonym: "thiol-activated aminopeptidase activity" RELATED [EC:3.4.11.14]
xref: EC:3.4.11.14
+xref: EC:3.4.11.2
xref: MetaCyc:3.4.11.14-RXN
is_a: GO:0004177 ! aminopeptidase activity
+property_value: skos:exactMatch EC:3.4.11.14
+property_value: skos:narrowMatch EC:3.4.11.2
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28557" xsd:anyURI
[Term]
@@ -125797,6 +130514,9 @@
xref: Reactome:R-HSA-75879 "palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH"
xref: RHEA:17657
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.42
+property_value: skos:exactMatch RHEA:17657
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016289
@@ -125808,7 +130528,9 @@
xref: RHEA:70423
is_a: GO:0016790 ! thiolester hydrolase activity
is_a: GO:0160215 ! deacylase activity
+property_value: skos:exactMatch RHEA:70423
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26441" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016290
@@ -125870,10 +130592,26 @@
synonym: "acyl-ACP-hydrolase activity" RELATED []
synonym: "acyl-acyl carrier protein hydrolase activity" RELATED []
synonym: "acyl-acyl-carrier-protein hydrolase activity" RELATED []
+xref: EC:3.1.2.14
+xref: EC:3.1.2.21
+xref: KEGG_REACTION:R08159
+xref: KEGG_REACTION:R08162
+xref: MetaCyc:3.1.2.14-RXN
+xref: MetaCyc:RXN-10727
xref: MetaCyc:RXN-7902
+xref: MetaCyc:RXN-9549
xref: Reactome:R-HSA-5655955 "OLAH hydrolyzes decanoyl-FASN dimer to DECA and FASN dimer"
xref: RHEA:44596
is_a: GO:0016790 ! thiolester hydrolase activity
+property_value: skos:exactMatch MetaCyc:RXN-7902
+property_value: skos:exactMatch RHEA:44596
+property_value: skos:narrowMatch EC:3.1.2.14
+property_value: skos:narrowMatch EC:3.1.2.21
+property_value: skos:narrowMatch KEGG_REACTION:R08159
+property_value: skos:narrowMatch KEGG_REACTION:R08162
+property_value: skos:narrowMatch MetaCyc:3.1.2.14-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-10727
+property_value: skos:narrowMatch MetaCyc:RXN-9549
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25677" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -125964,7 +130702,10 @@
xref: RHEA:12709
is_a: GO:0052742 ! phosphatidylinositol kinase activity
relationship: part_of GO:0036092 ! phosphatidylinositol-3-phosphate biosynthetic process
+property_value: skos:exactMatch EC:2.7.1.137
+property_value: skos:exactMatch RHEA:12709
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28336" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016304
@@ -126039,7 +130780,10 @@
xref: Reactome:R-HSA-8868066 "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2"
xref: RHEA:14425
is_a: GO:0052742 ! phosphatidylinositol kinase activity
+property_value: skos:exactMatch EC:2.7.1.68
+property_value: skos:exactMatch RHEA:14425
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28336" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016309
@@ -126056,7 +130800,10 @@
xref: Reactome:R-HSA-6811522 "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus"
xref: RHEA:12280
is_a: GO:0052742 ! phosphatidylinositol kinase activity
+property_value: skos:exactMatch EC:2.7.1.149
+property_value: skos:exactMatch RHEA:12280
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28336" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016310
@@ -126089,6 +130836,8 @@
xref: Reactome:R-HSA-6809565 "I(1,3)P2 is dephosphorylated into I1P by MTMR7:MTMR9"
xref: RHEA:57840
is_a: GO:0052745 ! inositol phosphate phosphatase activity
+property_value: skos:exactMatch RHEA:57840
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016313
@@ -126118,6 +130867,9 @@
xref: Reactome:R-HSA-2317387 "PTEN cancer mutants do not dephosphorylate PIP3"
xref: RHEA:25017
is_a: GO:0034594 ! phosphatidylinositol trisphosphate phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.67
+property_value: skos:exactMatch RHEA:25017
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016316
@@ -126135,7 +130887,10 @@
is_a: GO:0034596 ! phosphatidylinositol phosphate 4-phosphatase activity
is_a: GO:0106017 ! phosphatidylinositol-3,4-bisphosphate phosphatase activity
relationship: part_of GO:0036092 ! phosphatidylinositol-3-phosphate biosynthetic process
+property_value: skos:exactMatch EC:3.1.3.66
+property_value: skos:exactMatch RHEA:17193
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24252" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016318
@@ -126510,6 +131265,7 @@
def: "Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals." [GOC:mah, PMID:8622651]
synonym: "type I activin receptor activity" EXACT []
is_a: GO:0017002 ! activin receptor activity
+property_value: skos:broadMatch EC:2.7.11.30
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -126520,6 +131276,7 @@
synonym: "type II activin receptor activity" EXACT []
xref: Reactome:R-HSA-201443 "Type II receptor phosphorylates type I receptor"
is_a: GO:0017002 ! activin receptor activity
+property_value: skos:broadMatch EC:2.7.11.30
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -126553,6 +131310,7 @@
xref: Reactome:R-HSA-389891 "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)"
xref: RHEA:40459
is_a: GO:0003997 ! acyl-CoA oxidase activity
+property_value: skos:exactMatch RHEA:40459
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28733" xsd:anyURI
[Term]
@@ -126569,6 +131327,9 @@
xref: Reactome:R-HSA-5693373 "DDAH1 hydrolyses ADMA to DMA and L-Cit"
xref: RHEA:17305
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.18
+property_value: skos:exactMatch RHEA:17305
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016404
@@ -126591,6 +131352,9 @@
xref: Reactome:R-HSA-9024766 "HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1"
xref: RHEA:11876
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.141
+property_value: skos:exactMatch RHEA:11876
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016405
@@ -126600,6 +131364,7 @@
xref: Reactome:R-HSA-159443 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate"
xref: Reactome:R-HSA-159567 "ACSM2B-like proteins transform ST to ST-CoA"
xref: Reactome:R-HSA-177157 "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate"
+xref: Reactome:R-HSA-6798345 "PXLP-GCAT dimer ligates CoASH to 2A-3OB to form Gly and Ac-CoA"
xref: Reactome:R-HSA-9749971 "ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA"
is_a: GO:0016877 ! ligase activity, forming carbon-sulfur bonds
@@ -126668,6 +131433,7 @@
def: "Catalysis of the reaction: a fatty acyl-CoA + L-seryl-[protein] = CoA + O-fatty acyl-L-seryl-[protein]." [RHEA:68272]
xref: RHEA:68272
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch RHEA:68272
[Term]
id: GO:0016413
@@ -126686,6 +131452,8 @@
xref: EC:2.3.1.273
xref: RHEA:56868
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.273
+property_value: skos:exactMatch RHEA:56868
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -126760,6 +131528,9 @@
xref: MetaCyc:2.1.1.62-RXN
xref: RHEA:22744
is_a: GO:0008174 ! mRNA methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.62
+property_value: skos:exactMatch RHEA:22744
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016423
@@ -126806,7 +131577,10 @@
xref: Reactome:R-HSA-8932765 "NSUN6 methylates cytidine-72 in tRNA(Cys) and tRNA(Thr)"
xref: RHEA:61468
is_a: GO:0016427 ! tRNA (cytidine) methyltransferase activity
+property_value: skos:exactMatch RHEA:61468
+property_value: skos:relatedMatch EC:2.1.1.202
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24771" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016429
@@ -126841,6 +131615,9 @@
xref: RHEA:16785
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0016426 ! tRNA (adenine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.55
+property_value: skos:exactMatch RHEA:16785
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016432
@@ -126853,7 +131630,10 @@
xref: RHEA:62432
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.5.1.25
+property_value: skos:exactMatch RHEA:62432
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30175" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016433
@@ -126896,6 +131676,9 @@
xref: RHEA:12885
is_a: GO:0000030 ! mannosyltransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.4.1.110
+property_value: skos:exactMatch RHEA:12885
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016441
@@ -127068,6 +131851,9 @@
is_a: GO:0005385 ! zinc ion transmembrane transporter activity
is_a: GO:0015662 ! P-type ion transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
+property_value: skos:exactMatch EC:7.2.2.12
+property_value: skos:exactMatch RHEA:20621
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016464
@@ -127079,6 +131865,8 @@
xref: EC:7.4.2.4
xref: MetaCyc:3.6.3.52-RXN
is_a: GO:0015450 ! protein-transporting ATPase activity
+property_value: skos:exactMatch EC:7.4.2.4
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016465
@@ -127291,7 +132079,6 @@
xref: Reactome:R-HSA-400508 "Incretin synthesis, secretion, and inactivation"
xref: Reactome:R-HSA-422085 "Synthesis, secretion, and deacylation of Ghrelin"
is_a: GO:0042445 ! hormone metabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0140448 ! signaling receptor ligand precursor processing
[Term]
@@ -127343,11 +132130,15 @@
synonym: "redox activity" EXACT []
xref: EC:1.-.-.-
xref: Reactome:R-HSA-1614362 "SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases"
+xref: Reactome:R-HSA-209921 "Monoiodinated tyrosine can be deiodinated"
+xref: Reactome:R-HSA-209960 "Diiodinated tyrosine can be deiodinated"
xref: Reactome:R-HSA-2161612 "PGH2 is reduced to PGF2a by FAM213B"
xref: Reactome:R-HSA-265296 "Arachidonate is oxidised to 5S-HpETE by ALOX5"
xref: Reactome:R-HSA-266051 "5S-HpETE is dehydrated to LTA4 by ALOX5"
xref: Reactome:R-HSA-390425 "FAR1 reduces PalmCoA to HXOL"
xref: Reactome:R-HSA-390438 "FAR2 reduces PalmCoA to HXOL"
+xref: Reactome:R-HSA-5662660 "Dopachrome is transformed to DHICA by DCT"
+xref: Reactome:R-HSA-8878581 "TYRP1 oxidises DHICA to IQCA"
xref: Reactome:R-HSA-8936442 "MARC1,MARC2 reduce N-hydroxylated compounds"
xref: Reactome:R-HSA-9020249 "Hydroperoxy reductase reduces 4(S)-Hp-17(S)-HDHA to RvD6"
xref: Reactome:R-HSA-9020260 "Hydroperoxy reductase reduces 7(S)-Hp-17(S)-HDHA to RvD5"
@@ -127360,6 +132151,8 @@
xref: Reactome:R-HSA-9693722 "Unknown sepiapterin synthase transforms PTHP to sepiapterin"
xref: Reactome:R-HSA-9759549 "Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin"
is_a: GO:0003824 ! catalytic activity
+property_value: skos:exactMatch EC:1.-.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016492
@@ -127532,7 +132325,10 @@
xref: MetaCyc:1.1.1.211-RXN
xref: RHEA:52656
is_a: GO:0003857 ! (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.211
+property_value: skos:exactMatch RHEA:52656
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30577" xsd:anyURI
[Term]
@@ -128369,7 +133165,10 @@
xref: RHEA:23652
is_a: GO:0016755 ! aminoacyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.3.2.5
+property_value: skos:exactMatch RHEA:23652
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016604
@@ -128468,6 +133267,8 @@
xref: EC:1.1.-.-
xref: Reactome:R-HSA-1500781 "Fgd1 reactivates F420"
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.1.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016615
@@ -128482,11 +133283,17 @@
namespace: molecular_function
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP." [EC:1.1.1.-]
xref: EC:1.1.1.-
+xref: MetaCyc:RXN-12898
xref: Reactome:R-HSA-9027625 "5-HEDH dehydrogenates 7-HDPAn-3 to 7-oxo-DPAn-3"
xref: Reactome:R-HSA-9027631 "5-HEDH dehydrogenates 7-HDHA to 7-oxo-DHA"
xref: Reactome:R-HSA-9027632 "5-HEDH dehydrogenates 5-HEPE to 5-oxo-EPA"
xref: Reactome:R-HSA-975629 "RDH11 reduces RBP2:atRAL to RBP2:atROL"
+xref: RHEA:25968
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.1.-
+property_value: skos:narrowMatch MetaCyc:RXN-12898
+property_value: skos:narrowMatch RHEA:25968
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016617
@@ -128500,6 +133307,9 @@
xref: MetaCyc:4-OXOPROLINE-REDUCTASE-RXN
xref: RHEA:13601
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.104
+property_value: skos:exactMatch RHEA:13601
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016618
@@ -128514,7 +133324,9 @@
xref: EC:1.1.1.81
xref: MetaCyc:HYDROXYPYRUVATE-REDUCTASE-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.81
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25789" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016620
@@ -128524,6 +133336,8 @@
xref: EC:1.2.1.-
xref: Reactome:R-HSA-1222583 "MscR reduces nitrosomycothiol to ammonia"
is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors
+property_value: skos:exactMatch EC:1.2.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016621
@@ -128542,6 +133356,9 @@
xref: MetaCyc:CINNAMOYL-COA-REDUCTASE-RXN
xref: RHEA:10620
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.44
+property_value: skos:exactMatch RHEA:10620
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016622
@@ -128550,6 +133367,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a cytochrome." [GOC:jl]
xref: EC:1.2.2.-
is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors
+property_value: skos:exactMatch EC:1.2.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016623
@@ -128558,6 +133377,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen." [EC:1.2.3.-]
xref: EC:1.2.3.-
is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors
+property_value: skos:exactMatch EC:1.2.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016624
@@ -128570,6 +133391,8 @@
xref: Reactome:R-HSA-9859148 "BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV"
xref: Reactome:R-HSA-9865121 "BCKDHA or BCKDHB loss-of-function mutants don't synthesize BCAA-CoA"
is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors
+property_value: skos:exactMatch EC:1.2.4.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016625
@@ -128579,6 +133402,8 @@
synonym: "oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulphur protein as acceptor" EXACT []
xref: EC:1.2.7.-
is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors
+property_value: skos:exactMatch EC:1.2.7.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016626
@@ -128597,8 +133422,11 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [EC:1.3.-.-]
synonym: "oxidoreductase activity, acting on the CH-CH group of donors, other acceptors" NARROW []
xref: EC:1.3.-.-
+xref: Reactome:R-HSA-2995334 "COX15 transforms heme O to heme A"
xref: Reactome:R-HSA-9661710 "An unknown oxidase oxidises D-UBGN to UBN"
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.3.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016628
@@ -128606,10 +133434,13 @@
namespace: molecular_function
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP." [EC:1.3.1.-]
xref: EC:1.3.1.-
+xref: Reactome:R-HSA-4419979 "SRD5A3 reduces pPNOL to DCHOL"
xref: Reactome:R-HSA-4755572 "Defective SRD5A3 does not reduce pPNOL to DCHOL"
xref: Reactome:R-HSA-9661726 "An unknown reductase reduces D-UBGN to STBN"
xref: Reactome:R-HSA-9661745 "An unknown BILR reduces BIL to D-UBGN"
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016629
@@ -128624,6 +133455,9 @@
xref: MetaCyc:12-OXOPHYTODIENOATE-REDUCTASE-RXN
xref: RHEA:21888
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.42
+property_value: skos:exactMatch RHEA:21888
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016630
@@ -128640,6 +133474,9 @@
xref: MetaCyc:RXN1F-10
xref: RHEA:11132
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.33
+property_value: skos:exactMatch RHEA:11132
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016631
@@ -128665,6 +133502,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome." [EC:1.3.2.-]
xref: EC:1.3.2.-
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016633
@@ -128682,6 +133521,9 @@
xref: MetaCyc:GALACTONOLACTONE-DEHYDROGENASE-RXN
xref: RHEA:32367
is_a: GO:0016632 ! oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.3.2.3
+property_value: skos:exactMatch RHEA:32367
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016634
@@ -128690,6 +133532,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces oxygen." [EC:1.3.3.-]
xref: EC:1.3.3.-
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016635
@@ -128698,6 +133542,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a quinone or related compound." [EC:1.3.5.-]
xref: EC:1.3.5.-
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.5.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016636
@@ -128707,6 +133553,8 @@
synonym: "oxidoreductase activity, acting on the CH-CH group of donors, iron-sulphur protein as acceptor" EXACT []
xref: EC:1.3.7.-
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.7.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016637
@@ -128726,6 +133574,8 @@
synonym: "oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors" NARROW []
xref: EC:1.4.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.4.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016639
@@ -128734,6 +133584,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP." [GOC:ai]
xref: EC:1.4.1.-
is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors
+property_value: skos:exactMatch EC:1.4.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016640
@@ -128742,6 +133594,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a cytochrome molecule." [GOC:ai]
xref: EC:1.4.2.-
is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors
+property_value: skos:exactMatch EC:1.4.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016641
@@ -128750,6 +133604,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule." [GOC:ai]
xref: EC:1.4.3.-
is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors
+property_value: skos:exactMatch EC:1.4.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016642
@@ -128759,6 +133615,8 @@
synonym: "oxidoreductase activity, acting on the CH-NH2 group of donors, disulphide as acceptor" EXACT []
xref: EC:1.4.4.-
is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors
+property_value: skos:exactMatch EC:1.4.4.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016643
@@ -128768,6 +133626,8 @@
synonym: "oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulphur protein as acceptor" EXACT []
xref: EC:1.4.7.-
is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors
+property_value: skos:exactMatch EC:1.4.7.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016644
@@ -128787,6 +133647,8 @@
synonym: "oxidoreductase activity, acting on the CH-NH group of donors, other acceptors" NARROW []
xref: EC:1.5.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.5.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016646
@@ -128795,6 +133657,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl]
xref: EC:1.5.1.-
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016647
@@ -128803,6 +133667,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl]
xref: EC:1.5.3.-
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016648
@@ -128812,6 +133678,8 @@
synonym: "oxidoreductase activity, acting on the CH-NH group of donors, disulphide as acceptor" EXACT []
xref: EC:1.5.4.-
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.4.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016649
@@ -128819,8 +133687,9 @@
namespace: molecular_function
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces quinone or similar compound." [GOC:jl]
xref: EC:1.5.5.-
-xref: Reactome:R-HSA-70670 "PRODH oxidises L-Pro to 1PYR-5COOH"
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.5.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016650
@@ -128844,6 +133713,8 @@
xref: Reactome:R-HSA-109343 "Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA"
xref: Reactome:R-HSA-8956458 "RNLS:FAD oxidises dh-beta-NAD to NAD+"
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.6.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016652
@@ -128853,6 +133724,8 @@
synonym: "oxidoreductase activity, acting on NAD or NADPH, NAD or NADP as acceptor" RELATED []
xref: EC:1.6.1.-
is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H
+property_value: skos:exactMatch EC:1.6.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016653
@@ -128863,6 +133736,8 @@
synonym: "oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor" RELATED []
xref: EC:1.6.2.-
is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H
+property_value: skos:exactMatch EC:1.6.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016655
@@ -128872,6 +133747,8 @@
synonym: "oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor" RELATED []
xref: EC:1.6.5.-
is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H
+property_value: skos:exactMatch EC:1.6.5.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016656
@@ -128897,6 +133774,8 @@
xref: MetaCyc:1.6.5.4-RXN
xref: RHEA:14581
is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.6.5.4
+property_value: skos:exactMatch RHEA:14581
[Term]
id: GO:0016657
@@ -128937,6 +133816,8 @@
synonym: "oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors" NARROW []
xref: EC:1.7.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.7.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016662
@@ -128945,6 +133826,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a cytochrome." [EC:1.7.2.-]
xref: EC:1.7.2.-
is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors
+property_value: skos:exactMatch EC:1.7.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016663
@@ -128953,6 +133836,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces oxygen." [EC:1.7.3.-, GOC:jl]
xref: EC:1.7.3.-
is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors
+property_value: skos:exactMatch EC:1.7.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016664
@@ -128962,6 +133847,8 @@
synonym: "oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulphur protein as acceptor" EXACT []
xref: EC:1.7.7.-
is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors
+property_value: skos:exactMatch EC:1.7.7.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016665
@@ -128983,6 +133870,8 @@
xref: EC:1.8.-.-
xref: Reactome:R-HSA-2213240 "Reduction of disulphide bonds in MHC II antigens"
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.8.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016668
@@ -128996,6 +133885,8 @@
synonym: "oxidoreductase activity, acting on sulphur group of donors, NAD or NADP as acceptor" EXACT []
xref: EC:1.8.1.-
is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors
+property_value: skos:exactMatch EC:1.8.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016669
@@ -129005,6 +133896,8 @@
synonym: "oxidoreductase activity, acting on sulphur group of donors, cytochrome as acceptor" EXACT []
xref: EC:1.8.2.-
is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors
+property_value: skos:exactMatch EC:1.8.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016670
@@ -129014,6 +133907,8 @@
synonym: "oxidoreductase activity, acting on sulphur group of donors, oxygen as acceptor" EXACT []
xref: EC:1.8.3.-
is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors
+property_value: skos:exactMatch EC:1.8.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016671
@@ -129022,8 +133917,9 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide." [GOC:jl]
synonym: "oxidoreductase activity, acting on sulphur group of donors, disulphide as acceptor" EXACT []
xref: EC:1.8.4.-
-xref: Reactome:R-HSA-9035484 "MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST"
is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors
+property_value: skos:exactMatch EC:1.8.4.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016672
@@ -129033,6 +133929,8 @@
synonym: "oxidoreductase activity, acting on sulphur group of donors, quinone or similar compound as acceptor" EXACT []
xref: EC:1.8.5.-
is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors
+property_value: skos:exactMatch EC:1.8.5.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016673
@@ -129042,6 +133940,8 @@
synonym: "oxidoreductase activity, acting on sulphur group of donors, iron-sulphur protein as acceptor" EXACT []
xref: EC:1.8.7.-
is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors
+property_value: skos:exactMatch EC:1.8.7.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016674
@@ -129062,7 +133962,10 @@
synonym: "oxidoreductase activity, acting on haem group of donors" EXACT []
synonym: "oxidoreductase activity, acting on heme group of donors, other acceptors" NARROW []
xref: EC:1.9.-.-
+xref: Reactome:R-HSA-5340226 "CYGB dioxygenates NO"
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.9.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016676
@@ -129082,6 +133985,8 @@
synonym: "oxidoreductase activity, acting on haem group of donors, nitrogenous group as acceptor" EXACT []
xref: EC:1.9.6.-
is_a: GO:0016675 ! oxidoreductase activity, acting on a heme group of donors
+property_value: skos:exactMatch EC:1.9.6.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016678
@@ -129102,6 +134007,8 @@
synonym: "oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors" NARROW []
xref: EC:1.10.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.10.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016680
@@ -129110,6 +134017,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl]
xref: EC:1.10.1.-
is_a: GO:0016679 ! oxidoreductase activity, acting on diphenols and related substances as donors
+property_value: skos:exactMatch EC:1.10.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016681
@@ -129127,6 +134036,8 @@
synonym: "laccase activity" RELATED [GOC:jh]
xref: EC:1.10.3.-
is_a: GO:0016679 ! oxidoreductase activity, acting on diphenols and related substances as donors
+property_value: skos:exactMatch EC:1.10.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016683
@@ -129145,6 +134056,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor." [EC:1.11.-.-]
xref: EC:1.11.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.11.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016688
@@ -129160,6 +134073,9 @@
xref: MetaCyc:RXN-12440
xref: RHEA:22996
is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch EC:1.11.1.11
+property_value: skos:exactMatch RHEA:22996
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016689
@@ -129174,6 +134090,9 @@
xref: MetaCyc:MANGANESE-PEROXIDASE-RXN
xref: RHEA:22776
is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch EC:1.11.1.13
+property_value: skos:exactMatch RHEA:22776
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016690
@@ -129191,6 +134110,9 @@
xref: MetaCyc:RXN-17136
xref: RHEA:30271
is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch EC:1.11.1.14
+property_value: skos:exactMatch RHEA:30271
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016691
@@ -129212,7 +134134,9 @@
xref: EC:1.11.1.10
xref: MetaCyc:CHLORIDE-PEROXIDASE-RXN
is_a: GO:0140905 ! haloperoxidase activity
+property_value: skos:exactMatch EC:1.11.1.10
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23587" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016692
@@ -129230,6 +134154,9 @@
xref: MetaCyc:NADH-PEROXIDASE-RXN
xref: RHEA:18509
is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch EC:1.11.1.1
+property_value: skos:exactMatch RHEA:18509
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016694
@@ -129250,6 +134177,8 @@
synonym: "oxidoreductase activity, acting on hydrogen as donor, other acceptors" NARROW []
xref: EC:1.12.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.12.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016696
@@ -129258,6 +134187,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP." [GOC:jl]
xref: EC:1.12.1.-
is_a: GO:0016695 ! oxidoreductase activity, acting on hydrogen as donor
+property_value: skos:exactMatch EC:1.12.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016697
@@ -129267,6 +134198,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces a cytochrome." [GOC:jl]
xref: EC:1.12.2.-
is_a: GO:0016695 ! oxidoreductase activity, acting on hydrogen as donor
+property_value: skos:exactMatch EC:1.12.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016699
@@ -129278,6 +134211,8 @@
synonym: "oxidoreductase activity, acting on hydrogen as donor, iron-sulphur protein as acceptor" EXACT []
xref: EC:1.12.7.-
is_a: GO:0016695 ! oxidoreductase activity, acting on hydrogen as donor
+property_value: skos:exactMatch EC:1.12.7.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016700
@@ -129325,6 +134260,8 @@
xref: Reactome:R-HSA-9027633 "ALOX5 oxidises DPAn-3 to 7-HDPAn-3"
xref: Reactome:R-HSA-9028255 "PTGS2 dimer oxidises EPA to PGH3"
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.13.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016702
@@ -129343,6 +134280,8 @@
xref: Reactome:R-HSA-9916401 "ALOX12 oxidises LTA4 to LXB4"
is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
is_a: GO:0051213 ! dioxygenase activity
+property_value: skos:exactMatch EC:1.13.11.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016703
@@ -129352,6 +134291,8 @@
xref: EC:1.13.12.-
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
+property_value: skos:exactMatch EC:1.13.12.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016704
@@ -129370,8 +134311,9 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor." [EC:1.14.-.-]
synonym: "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous" NARROW []
xref: EC:1.14.-.-
-xref: Reactome:R-HSA-5333612 "MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal"
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.14.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
[Term]
@@ -129387,6 +134329,8 @@
xref: Reactome:R-HSA-6783455 "TYW5 hydroxylates yW-72 yielding OHyW-72 at nucleotide 37 of tRNA(Phe)"
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
is_a: GO:0051213 ! dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016707
@@ -129402,6 +134346,9 @@
xref: MetaCyc:RXN1F-170
xref: RHEA:10104
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.15
+property_value: skos:exactMatch RHEA:10104
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016708
@@ -129412,6 +134359,8 @@
xref: EC:1.14.12.-
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
is_a: GO:0051213 ! dioxygenase activity
+property_value: skos:exactMatch EC:1.14.12.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
[Term]
@@ -129427,6 +134376,8 @@
xref: Reactome:R-HSA-6786239 "CYP4V2 omega-hydroxylates DHA to HDoHE"
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.13.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
[Term]
@@ -129453,6 +134404,9 @@
xref: MetaCyc:TRANS-CINNAMATE-4-MONOOXYGENASE-RXN
xref: RHEA:10608
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.91
+property_value: skos:exactMatch RHEA:10608
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016711
@@ -129468,6 +134422,9 @@
xref: MetaCyc:FLAVONOID-3-MONOOXYGENASE-RXN
xref: RHEA:16337
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.82
+property_value: skos:exactMatch RHEA:16337
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016712
@@ -129489,10 +134446,17 @@
synonym: "unspecific monooxygenase activity" NARROW []
synonym: "xenobiotic monooxygenase activity" NARROW [EC:1.14.14.1]
xref: EC:1.14.14.-
+xref: EC:1.14.14.1
+xref: MetaCyc:UNSPECIFIC-MONOOXYGENASE-RXN
xref: Reactome:R-HSA-194678 "CYP51A1 demethylates LNSOL"
xref: Reactome:R-HSA-211966 "CYP2D6 4-hydroxylates debrisoquine"
+xref: RHEA:17149
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.14.-
+property_value: skos:narrowMatch EC:1.14.14.1
+property_value: skos:narrowMatch MetaCyc:UNSPECIFIC-MONOOXYGENASE-RXN
+property_value: skos:narrowMatch RHEA:17149
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28295" xsd:anyURI
created_by: mah
@@ -129505,6 +134469,8 @@
xref: EC:1.14.15.-
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.15.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
[Term]
@@ -129515,6 +134481,8 @@
xref: EC:1.14.16.-
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.16.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
[Term]
@@ -129525,6 +134493,8 @@
xref: EC:1.14.17.-
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.17.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
[Term]
@@ -129535,6 +134505,8 @@
xref: EC:1.14.18.-
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.18.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
[Term]
@@ -129544,6 +134516,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water." [EC:1.14.19.-]
xref: EC:1.14.19.-
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.19.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
[Term]
@@ -129568,11 +134542,14 @@
xref: MetaCyc:RXN-12242
xref: RHEA:30955
is_a: GO:0016635 ! oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor
+property_value: skos:exactMatch EC:1.3.5.6
+property_value: skos:exactMatch MetaCyc:RXN-12242
+property_value: skos:exactMatch RHEA:30955
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25964" xsd:anyURI
[Term]
id: GO:0016720
-name: acyl-lipid Delta(12)-acetylenase
+name: acyl-lipid Delta(12)-acetylenase activity
namespace: molecular_function
def: "Catalysis of the reaction: (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = a (9Z)-octadec-9-en-12-ynoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O." [RHEA:46552]
synonym: "D12-fatty acid dehydrogenase activity" EXACT []
@@ -129584,7 +134561,10 @@
xref: MetaCyc:1.14.99.33-RXN
xref: RHEA:46552
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.39
+property_value: skos:exactMatch RHEA:46552
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016721
@@ -129593,6 +134573,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a superoxide radical (O2- or O2.-) acts as a hydrogen or electron acceptor." [GOC:ai]
xref: EC:1.15.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.15.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016722
@@ -129604,7 +134586,9 @@
xref: EC:1.16.-.-
xref: Reactome:R-HSA-917805 "CYBRD1:Heme reduces Fe3+ to Fe2+"
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.16.-.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20675" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016723
@@ -129615,7 +134599,9 @@
synonym: "oxidoreductase activity, reducing metal ions, NAD or NADP as acceptor" RELATED []
xref: EC:1.16.1.-
is_a: GO:0016722 ! oxidoreductase activity, acting on metal ions
+property_value: skos:exactMatch EC:1.16.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20675" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016724
@@ -129625,7 +134611,9 @@
synonym: "oxidoreductase activity, oxidizing metal ions, oxygen as acceptor" RELATED []
xref: EC:1.16.3.-
is_a: GO:0016722 ! oxidoreductase activity, acting on metal ions
+property_value: skos:exactMatch EC:1.16.3.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20682" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016725
@@ -129635,6 +134623,8 @@
synonym: "oxidoreductase activity, acting on CH or CH2 groups, other acceptors" NARROW []
xref: EC:1.17.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.17.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016726
@@ -129643,6 +134633,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP." [GOC:ai]
xref: EC:1.17.1.-
is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups
+property_value: skos:exactMatch EC:1.17.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016727
@@ -129651,6 +134643,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule." [GOC:ai]
xref: EC:1.17.3.-
is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups
+property_value: skos:exactMatch EC:1.17.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016728
@@ -129660,6 +134654,8 @@
synonym: "oxidoreductase activity, acting on CH or CH2 groups, disulphide as acceptor" EXACT []
xref: EC:1.17.4.-
is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups
+property_value: skos:exactMatch EC:1.17.4.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016729
@@ -129679,6 +134675,8 @@
synonym: "oxidoreductase activity, acting on iron-sulphur proteins as donors" EXACT []
xref: EC:1.18.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.18.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016731
@@ -129687,6 +134685,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl]
xref: EC:1.18.1.-
is_a: GO:0016730 ! oxidoreductase activity, acting on iron-sulfur proteins as donors
+property_value: skos:exactMatch EC:1.18.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016732
@@ -129695,6 +134695,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces dinitrogen." [GOC:jl]
xref: EC:1.18.6.-
is_a: GO:0016730 ! oxidoreductase activity, acting on iron-sulfur proteins as donors
+property_value: skos:exactMatch EC:1.18.6.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016733
@@ -129736,6 +134738,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [EC:1.19.-.-]
xref: EC:1.19.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.19.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016738
@@ -129744,6 +134748,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces dinitrogen." [GOC:jl]
xref: EC:1.19.6.-
is_a: GO:0016737 ! oxidoreductase activity, acting on reduced flavodoxin as donor
+property_value: skos:exactMatch EC:1.19.6.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016739
@@ -129773,10 +134779,11 @@
xref: EC:2.-.-.-
xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2"
xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1"
-xref: Reactome:R-HSA-5333607 "GSSeH combines with bGalNAc derivative to form GSSebGalNac"
xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK"
xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248"
is_a: GO:0003824 ! catalytic activity
+property_value: skos:exactMatch EC:2.-.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016741
@@ -129786,7 +134793,9 @@
synonym: "methyltransferase activity" NARROW []
xref: EC:2.1.-.-
is_a: GO:0016740 ! transferase activity
+property_value: skos:exactMatch EC:2.1.-.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016742
@@ -129795,6 +134804,8 @@
def: "Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor)." [EC:2.1.2.-, GOC:mah]
xref: EC:2.1.2.-
is_a: GO:0016741 ! transferase activity, transferring one-carbon groups
+property_value: skos:exactMatch EC:2.1.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016743
@@ -129804,6 +134815,8 @@
synonym: "carboxyl- and carbamoyltransferase activity" EXACT []
xref: EC:2.1.3.-
is_a: GO:0016741 ! transferase activity, transferring one-carbon groups
+property_value: skos:exactMatch EC:2.1.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016744
@@ -129814,7 +134827,9 @@
synonym: "transferase activity, transferring aldehyde or ketonic groups" EXACT []
xref: EC:2.2.1.-
is_a: GO:0016740 ! transferase activity
+property_value: skos:exactMatch EC:2.2.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016746
@@ -129831,7 +134846,9 @@
xref: Reactome:R-HSA-193491 "Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate"
xref: Reactome:R-HSA-8858298 "HRASLS transfer acyl group from PC to PE to form NAPE"
is_a: GO:0016740 ! transferase activity
+property_value: skos:exactMatch EC:2.3.-.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016747
@@ -129844,7 +134861,9 @@
xref: Reactome:R-HSA-9859163 "DBT transfers BCAA to CoA"
xref: Reactome:R-HSA-9865115 "DBT loss-of-function mutants don't synthesize BCAA-CoA"
is_a: GO:0016746 ! acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016748
@@ -129905,6 +134924,9 @@
xref: MetaCyc:2.3.1.92-RXN
xref: RHEA:12625
is_a: GO:0016753 ! O-sinapoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.92
+property_value: skos:exactMatch RHEA:12625
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016755
@@ -129914,6 +134936,8 @@
synonym: "transferase activity, transferring amino-acyl groups" EXACT []
xref: EC:2.3.2.-
is_a: GO:0016746 ! acyltransferase activity
+property_value: skos:exactMatch EC:2.3.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016756
@@ -129926,6 +134950,9 @@
xref: MetaCyc:2.3.2.15-RXN
xref: RHEA:17917
is_a: GO:0016755 ! aminoacyltransferase activity
+property_value: skos:exactMatch EC:2.3.2.15
+property_value: skos:exactMatch RHEA:17917
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016757
@@ -129944,6 +134971,8 @@
xref: Reactome:R-HSA-5173005 "B3GALTL transfers glucose to O-fucosyl-proteins"
xref: Reactome:R-HSA-6785565 "Defective B3GALTL does not transfer glucose to O-fucosyl-proteins"
is_a: GO:0016740 ! transferase activity
+property_value: skos:exactMatch EC:2.4.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016758
@@ -129953,6 +134982,8 @@
synonym: "transferase activity, transferring hexosyl groups" EXACT []
xref: EC:2.4.1.-
is_a: GO:0016757 ! glycosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016759
@@ -129987,10 +135018,12 @@
synonym: "uridine diphosphoglucose-cellulose glucosyltransferase activity" RELATED [EC:2.4.1.12]
xref: EC:2.4.1.12
xref: MetaCyc:CELLULOSE-SYNTHASE-UDP-FORMING-RXN
-xref: Reactome:R-HSA-9932210 "Bcs complex synthesizes cellulose from UDP-Glc"
xref: RHEA:19929
is_a: GO:0016759 ! cellulose synthase activity
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.12
+property_value: skos:exactMatch RHEA:19929
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016761
@@ -130008,6 +135041,9 @@
xref: MetaCyc:CELLULOSE-SYNTHASE-GDP-FORMING-RXN
xref: RHEA:17797
is_a: GO:0016759 ! cellulose synthase activity
+property_value: skos:exactMatch EC:2.4.1.29
+property_value: skos:exactMatch RHEA:17797
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016762
@@ -130022,6 +135058,8 @@
xref: EC:2.4.1.207
xref: MetaCyc:2.4.1.207-RXN
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.207
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016763
@@ -130033,7 +135071,9 @@
xref: Reactome:R-HSA-112265 "thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP]"
xref: Reactome:R-HSA-112266 "thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP]"
is_a: GO:0016757 ! glycosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016764
@@ -130060,6 +135100,8 @@
xref: Reactome:R-HSA-4755545 "Defective DHDDS does not elongate E,E-FPP"
xref: Reactome:R-HSA-6782893 "TRMT12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe)"
is_a: GO:0016740 ! transferase activity
+property_value: skos:exactMatch EC:2.5.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016767
@@ -130084,6 +135126,9 @@
xref: Reactome:R-HSA-351210 "dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine"
xref: RHEA:19973
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.22
+property_value: skos:exactMatch RHEA:19973
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016769
@@ -130093,6 +135138,8 @@
synonym: "transferase activity, transferring other nitrogenous groups" NARROW []
xref: EC:2.6.-.-
is_a: GO:0016740 ! transferase activity
+property_value: skos:exactMatch EC:2.6.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016771
@@ -130112,8 +135159,9 @@
comment: Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides.
subset: goslim_chembl
xref: EC:2.7.-.-
-xref: Reactome:R-HSA-9932322 "BcsG transfers pEtN from PE onto cellulose"
is_a: GO:0016740 ! transferase activity
+property_value: skos:exactMatch EC:2.7.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016773
@@ -130123,8 +135171,9 @@
subset: goslim_drosophila
xref: EC:2.7.1.-
xref: Reactome:R-HSA-2161193 "abacavir + AMP => abacavir monophosphate + adenosine"
-xref: Reactome:R-HSA-9941039 "FAM20B phosphorylates Xyl moiety"
is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups
+property_value: skos:exactMatch EC:2.7.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016774
@@ -130133,6 +135182,8 @@
def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor)." [EC:2.7.2.-]
xref: EC:2.7.2.-
is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups
+property_value: skos:exactMatch EC:2.7.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016775
@@ -130141,6 +135192,8 @@
def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor)." [EC:2.7.3.-]
xref: EC:2.7.3.-
is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups
+property_value: skos:exactMatch EC:2.7.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016776
@@ -130149,6 +135202,8 @@
def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor)." [EC:2.7.4.-]
xref: EC:2.7.4.-
is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups
+property_value: skos:exactMatch EC:2.7.4.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016778
@@ -130157,6 +135212,8 @@
def: "Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor)." [GOC:jl, PMID:1651917]
xref: EC:2.7.6.-
is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups
+property_value: skos:exactMatch EC:2.7.6.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016779
@@ -130171,6 +135228,8 @@
xref: EC:2.7.7.-
xref: Reactome:R-HSA-6782434 "THG1L transfers GMP to 5' end of tRNA(His)"
is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups
+property_value: skos:exactMatch EC:2.7.7.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016780
@@ -130180,9 +135239,9 @@
xref: EC:2.7.8.-
xref: Reactome:R-HSA-162742 "(ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI"
xref: Reactome:R-HSA-163069 "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol"
-xref: Reactome:R-HSA-9940735 "FKTN transfers RboP to GalNAc-GlcNAc-ManP-DAG1"
-xref: Reactome:R-HSA-9940756 "FKRP dimer transfers RboP to matriglycan chain"
is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups
+property_value: skos:exactMatch EC:2.7.8.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016781
@@ -130191,6 +135250,8 @@
def: "Catalysis of the transfer of two phosphate groups from a donor, such as ATP, to two different acceptors." [EC:2.7.9.-]
xref: EC:2.7.9.-
is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups
+property_value: skos:exactMatch EC:2.7.9.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016782
@@ -130199,7 +135260,9 @@
def: "Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor)." [EC:2.8.-.-]
xref: EC:2.8.-.-
is_a: GO:0016740 ! transferase activity
+property_value: skos:exactMatch EC:2.8.-.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016783
@@ -130210,12 +135273,10 @@
xref: EC:2.8.1.-
xref: Reactome:R-HSA-1614618 "Persulfide sulfur is transferred onto sulfite"
xref: Reactome:R-HSA-6782264 "CTU1:CTU2:URM1 thiolates uridine-34 in tRNAs"
-xref: Reactome:R-HSA-9012721 "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR"
-xref: Reactome:R-HSA-9013471 "MPST transfers sulfur from 3MPYR to HCN to form HSCN"
-xref: Reactome:R-HSA-9013533 "MPST transfers sulfur from sulfanegen to HCN to form HSCN"
-xref: Reactome:R-HSA-9034756 "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST"
xref: Reactome:R-HSA-947538 "Transfer of sulfur from MOCS3-S-S onto MOCS2A"
is_a: GO:0016782 ! transferase activity, transferring sulphur-containing groups
+property_value: skos:exactMatch EC:2.8.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016784
@@ -130228,8 +135289,14 @@
synonym: "mercaptopyruvate sulfurtransferase activity" EXACT []
xref: EC:2.8.1.2
xref: MetaCyc:MERCAPYSTRANS-RXN
+xref: Reactome:R-HSA-9012721 "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR"
+xref: Reactome:R-HSA-9013471 "MPST transfers sulfur from 3MPYR to HCN to form HSCN"
+xref: Reactome:R-HSA-9013533 "MPST transfers sulfur from sulfanegen to HCN to form HSCN"
+xref: Reactome:R-HSA-9034756 "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST"
xref: RHEA:21740
is_a: GO:0016783 ! sulfurtransferase activity
+property_value: skos:exactMatch EC:2.8.1.2
+property_value: skos:exactMatch RHEA:21740
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30160" xsd:anyURI
[Term]
@@ -130241,7 +135308,9 @@
synonym: "transferase activity, transferring selenium-containing groups" EXACT []
xref: EC:2.9.1.-
is_a: GO:0016740 ! transferase activity
+property_value: skos:exactMatch EC:2.9.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016787
@@ -130267,8 +135336,9 @@
xref: Reactome:R-HSA-6788295 "HDHD1:Mg2+ dephosphorylates PURIDP"
xref: Reactome:R-HSA-8938314 "ENPPs hydrolyse CoA-SH to PPANT, PAP"
xref: Reactome:R-HSA-8952137 "Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate"
-xref: Reactome:R-HSA-9942295 "QNG1 hydrolyzes queuosine 5'-monophosphate yielding queuine and ribose 5'-monophosphate"
is_a: GO:0003824 ! catalytic activity
+property_value: skos:exactMatch EC:3.-.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016788
@@ -130283,6 +135353,8 @@
xref: Reactome:R-HSA-9023619 "Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin"
xref: Reactome:R-HSA-9749609 "BCHE hydrolyzes ASA-"
is_a: GO:0016787 ! hydrolase activity
+property_value: skos:exactMatch EC:3.1.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016790
@@ -130292,6 +135364,8 @@
synonym: "thiolesterase activity" EXACT []
xref: EC:3.1.2.-
is_a: GO:0016788 ! hydrolase activity, acting on ester bonds
+property_value: skos:exactMatch EC:3.1.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016791
@@ -130311,9 +135385,10 @@
xref: Reactome:R-HSA-4419986 "Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL"
xref: Reactome:R-HSA-9636457 "SapM dephosphorylates PI3P"
xref: Reactome:R-HSA-9837419 "PANK4 hydrolyzes PPANT to pantetheine"
-xref: Reactome:R-HSA-9940993 "PXYLP1 dephosphorylates Xyl moiety"
is_a: GO:0042578 ! phosphoric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.3.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25755" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016793
@@ -130323,6 +135398,8 @@
xref: EC:3.1.5.-
xref: Reactome:R-HSA-8866601 "SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate"
is_a: GO:0042578 ! phosphoric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.5.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016794
@@ -130331,6 +135408,8 @@
def: "Catalysis of the hydrolysis of a diphosphoester, releasing a diphosphate and a free hydroxyl group." [EC:3.1.7.-]
xref: EC:3.1.7.-
is_a: GO:0042578 ! phosphoric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.7.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016795
@@ -130339,6 +135418,8 @@
def: "Catalysis of the hydrolysis of a phosphoric triester." [EC:3.1.8.-, GOC:curators]
xref: EC:3.1.8.-
is_a: GO:0042578 ! phosphoric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.8.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016796
@@ -130377,8 +135458,9 @@
xref: EC:3.2.-.-
xref: Reactome:R-HSA-1793176 "DS is cleaved from its proteoglycan"
xref: Reactome:R-HSA-2065233 "CS is cleaved from its proteoglycan"
-xref: Reactome:R-HSA-5333609 "MeSebGalNac is hydrolysed to MeSeH and bGalNac"
is_a: GO:0016787 ! hydrolase activity
+property_value: skos:exactMatch EC:3.2.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016799
@@ -130387,6 +135469,8 @@
def: "Catalysis of the hydrolysis of any N-glycosyl bond." [GOC:jl]
xref: EC:3.2.2.-
is_a: GO:0016798 ! hydrolase activity, acting on glycosyl bonds
+property_value: skos:exactMatch EC:3.2.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016801
@@ -130395,6 +135479,8 @@
def: "Catalysis of the hydrolysis of any ether or thioether bond, -O- or -S- respectively." [GOC:ai, GOC:jl]
xref: EC:3.3.-.-
is_a: GO:0016787 ! hydrolase activity
+property_value: skos:exactMatch EC:3.3.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016802
@@ -130405,6 +135491,8 @@
synonym: "trialkylsulphonium hydrolase activity" EXACT []
xref: EC:3.3.1.-
is_a: GO:0016801 ! hydrolase activity, acting on ether bonds
+property_value: skos:exactMatch EC:3.3.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016803
@@ -130414,6 +135502,8 @@
xref: EC:3.3.2.-
xref: Reactome:R-HSA-8874435 "THEM86B hydrolyses PMCHO, PMETAM"
is_a: GO:0016801 ! hydrolase activity, acting on ether bonds
+property_value: skos:exactMatch EC:3.3.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016804
@@ -130437,13 +135527,23 @@
def: "Catalysis of the hydrolysis of a dipeptide." [EC:3.4.13.-, https://www.ebi.ac.uk/merops/about/glossary.shtml#DIPEPTIDASE, PMID:19879002]
synonym: "cytosolic dipeptidase activity" NARROW []
xref: EC:3.4.13.-
+xref: EC:3.4.13.18
+xref: EC:3.4.13.19
+xref: EC:3.4.13.21
xref: MetaCyc:3.4.13.18-RXN
+xref: MetaCyc:3.4.13.21-RXN
xref: Reactome:R-HSA-266012 "LTD4 is converted to LTE4 by DPEP1/2"
xref: Reactome:R-HSA-5433067 "DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG"
xref: Reactome:R-HSA-5693783 "NAALADases hydrolyse NAAG"
xref: Reactome:R-HSA-9026771 "DPEP hydrolyses MCTR2 to MCTR3"
is_a: GO:0008238 ! exopeptidase activity
+property_value: skos:exactMatch EC:3.4.13.-
+property_value: skos:narrowMatch EC:3.4.13.18
+property_value: skos:narrowMatch EC:3.4.13.19
+property_value: skos:narrowMatch EC:3.4.13.21
+property_value: skos:narrowMatch MetaCyc:3.4.13.21-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016806
@@ -130460,10 +135560,16 @@
namespace: molecular_function
def: "Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CARBOXYPEPTIDASE]
xref: EC:3.4.18.-
+xref: EC:3.4.18.1
+xref: MetaCyc:3.4.18.1-RXN
is_a: GO:0004180 ! carboxypeptidase activity
is_a: GO:0070004 ! cysteine-type exopeptidase activity
+property_value: skos:exactMatch EC:3.4.18.-
+property_value: skos:narrowMatch EC:3.4.18.1
+property_value: skos:narrowMatch MetaCyc:3.4.18.1-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19681" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28099" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016808
@@ -130486,6 +135592,8 @@
xref: EC:3.5.-.-
xref: Reactome:R-HSA-6803753 "NAAA hydrolyses NAEs to FAs and ethanolamine"
is_a: GO:0016787 ! hydrolase activity
+property_value: skos:exactMatch EC:3.5.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016811
@@ -130496,6 +135604,8 @@
xref: Reactome:R-HSA-9673053 "PM20D1 transforms oleoyl-phe from oleate and phe"
xref: Reactome:R-HSA-9673054 "PM20D1 hydrolyzes oleoyl-phe"
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch EC:3.5.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016812
@@ -130503,8 +135613,10 @@
namespace: molecular_function
def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide." [EC:3.5.2.-]
xref: EC:3.5.2.-
-xref: Reactome:R-HSA-70906 "4-imidazolone-5-propanoate + H2O => N-formiminoglutamate"
+xref: Reactome:R-HSA-70906 "4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+"
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch EC:3.5.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016813
@@ -130513,6 +135625,8 @@
def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2." [EC:3.5.3.-]
xref: EC:3.5.3.-
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch EC:3.5.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016814
@@ -130521,6 +135635,8 @@
def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2." [EC:3.5.4.-]
xref: EC:3.5.4.-
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch EC:3.5.4.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016815
@@ -130529,6 +135645,8 @@
def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN." [GOC:curators]
xref: EC:3.5.5.-
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch EC:3.5.5.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016816
@@ -130548,6 +135666,8 @@
synonym: "hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement" NARROW []
xref: EC:3.6.-.-
is_a: GO:0016787 ! hydrolase activity
+property_value: skos:exactMatch EC:3.6.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016818
@@ -130559,6 +135679,8 @@
xref: Reactome:R-HSA-9731613 "NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP"
xref: Reactome:R-HSA-9731632 "NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP"
is_a: GO:0016817 ! hydrolase activity, acting on acid anhydrides
+property_value: skos:exactMatch EC:3.6.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016819
@@ -130568,6 +135690,8 @@
synonym: "hydrolase activity, acting on acid anhydrides, in sulphonyl-containing anhydrides" EXACT []
xref: EC:3.6.2.-
is_a: GO:0016817 ! hydrolase activity, acting on acid anhydrides
+property_value: skos:exactMatch EC:3.6.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016821
@@ -130581,61 +135705,82 @@
[Term]
id: GO:0016822
-name: hydrolase activity, acting on acid carbon-carbon bonds
+name: hydrolase activity, acting on carbon-carbon bonds
namespace: molecular_function
-def: "Catalysis of the hydrolysis of any acid carbon-carbon bond." [GOC:jl]
+def: "Catalysis of the hydrolysis of any carbon-carbon bond." [EC:3.7.-.-]
xref: EC:3.7.-.-
is_a: GO:0016787 ! hydrolase activity
+property_value: skos:exactMatch EC:3.7.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30700" xsd:anyURI
[Term]
id: GO:0016823
-name: hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+name: hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
namespace: molecular_function
-def: "Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group." [EC:3.7.1.-]
+def: "Catalysis of the hydrolysis of any carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group." [EC:3.7.1.-]
xref: EC:3.7.1.-
-is_a: GO:0016822 ! hydrolase activity, acting on acid carbon-carbon bonds
+is_a: GO:0016822 ! hydrolase activity, acting on carbon-carbon bonds
+property_value: skos:exactMatch EC:3.7.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30700" xsd:anyURI
[Term]
id: GO:0016824
-name: hydrolase activity, acting on acid halide bonds
+name: hydrolase activity, acting on halide bonds
namespace: molecular_function
-def: "Catalysis of the hydrolysis of any acid halide bond." [EC:3.8.-.-]
+def: "Catalysis of the hydrolysis of any halide bond." [EC:3.8.-.-]
xref: EC:3.8.-.-
is_a: GO:0016787 ! hydrolase activity
+property_value: skos:exactMatch EC:3.8.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30700" xsd:anyURI
[Term]
id: GO:0016825
-name: hydrolase activity, acting on acid phosphorus-nitrogen bonds
+name: hydrolase activity, acting on phosphorus-nitrogen bonds
namespace: molecular_function
-def: "Catalysis of the hydrolysis of any acid phosphorus-nitrogen bond." [EC:3.9.1.-]
+def: "Catalysis of the hydrolysis of any phosphorus-nitrogen bond." [EC:3.9.1.-]
xref: EC:3.9.1.-
is_a: GO:0016787 ! hydrolase activity
+property_value: skos:exactMatch EC:3.9.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30700" xsd:anyURI
[Term]
id: GO:0016826
-name: hydrolase activity, acting on acid sulfur-nitrogen bonds
+name: hydrolase activity, acting on sulfur-nitrogen bonds
namespace: molecular_function
-def: "Catalysis of the hydrolysis of any acid sulfur-nitrogen bond." [EC:3.10.-.-]
-synonym: "hydrolase activity, acting on acid sulphur-nitrogen bonds" EXACT []
+def: "Catalysis of the hydrolysis of any sulfur-nitrogen bond." [EC:3.10.-.-]
+synonym: "hydrolase activity, acting on sulphur-nitrogen bonds" EXACT []
xref: EC:3.10.-.-
is_a: GO:0016787 ! hydrolase activity
+property_value: skos:exactMatch EC:3.10.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30700" xsd:anyURI
[Term]
id: GO:0016827
-name: hydrolase activity, acting on acid carbon-phosphorus bonds
+name: hydrolase activity, acting on carbon-phosphorus bonds
namespace: molecular_function
-def: "Catalysis of the hydrolysis of any acid carbon-phosphorus bond." [EC:3.11.-.-]
+def: "Catalysis of the hydrolysis of any carbon-phosphorus bond." [EC:3.11.-.-]
xref: EC:3.11.-.-
is_a: GO:0016787 ! hydrolase activity
+property_value: skos:exactMatch EC:3.11.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30700" xsd:anyURI
[Term]
id: GO:0016828
-name: hydrolase activity, acting on acid sulfur-sulfur bonds
+name: hydrolase activity, acting on sulfur-sulfur bonds
namespace: molecular_function
-def: "Catalysis of the hydrolysis of any acid sulfur-sulfur bond." [EC:3.12.-.-]
-synonym: "hydrolase activity, acting on acid sulphur-sulphur bonds" EXACT []
+def: "Catalysis of the hydrolysis of any sulfur-sulfur bond." [EC:3.12.-.-]
+synonym: "hydrolase activity, acting on sulphur-sulphur bonds" EXACT []
xref: EC:3.12.-.-
is_a: GO:0016787 ! hydrolase activity
+property_value: skos:exactMatch EC:3.12.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30700" xsd:anyURI
[Term]
id: GO:0016829
@@ -130654,6 +135799,8 @@
xref: Reactome:R-HSA-5696408 "PXLP-K278-PHYKPL tetramer hydrolyses 5PHL"
xref: Reactome:R-HSA-6782895 "TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe)"
is_a: GO:0003824 ! catalytic activity
+property_value: skos:exactMatch EC:4.-.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016830
@@ -130666,6 +135813,8 @@
xref: Reactome:R-HSA-190182 "UROD decarboxylates URO1 to COPRO1"
xref: Reactome:R-HSA-389611 "2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA"
is_a: GO:0016829 ! lyase activity
+property_value: skos:exactMatch EC:4.1.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016831
@@ -130677,8 +135826,9 @@
xref: Reactome:R-HSA-6787757 "PXLP-K333-GADL1 decarboxylates acidic AAs"
xref: Reactome:R-HSA-6814165 "PXLP-K333-GADL1 decarboxylates CSA to HTAU"
xref: Reactome:R-HSA-71223 "2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2"
-xref: Reactome:R-HSA-9856737 "Unknown enzyme(s) process 4-HMA to 4-Hbz"
is_a: GO:0016830 ! carbon-carbon lyase activity
+property_value: skos:exactMatch EC:4.1.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016832
@@ -130692,6 +135842,8 @@
xref: Reactome:R-HSA-200735 "SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG"
xref: Reactome:R-HSA-71249 "SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly"
is_a: GO:0016830 ! carbon-carbon lyase activity
+property_value: skos:exactMatch EC:4.1.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016833
@@ -130702,6 +135854,8 @@
synonym: "oxoacid lyase activity" EXACT []
xref: EC:4.1.3.-
is_a: GO:0016830 ! carbon-carbon lyase activity
+property_value: skos:exactMatch EC:4.1.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016834
@@ -130721,6 +135875,8 @@
synonym: "other carbon-oxygen lyase activity" NARROW []
xref: EC:4.2.-.-
is_a: GO:0016829 ! lyase activity
+property_value: skos:exactMatch EC:4.2.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016836
@@ -130729,7 +135885,10 @@
def: "Catalysis of the cleavage of a carbon-oxygen bond by elimination of water." [EC:4.2.1.-]
xref: EC:4.2.1.-
xref: Reactome:R-HSA-2161659 "PGE2 is dehydrated to PGA2"
+xref: Reactome:R-HSA-9014627 "SDS dimers:PXLP dehydrate L-Thr to 2AA"
is_a: GO:0016835 ! carbon-oxygen lyase activity
+property_value: skos:exactMatch EC:4.2.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016837
@@ -130738,7 +135897,9 @@
def: "Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide." [EC:4.2.2.-]
xref: EC:4.2.2.-
is_a: GO:0016835 ! carbon-oxygen lyase activity
+property_value: skos:exactMatch EC:4.2.2.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21167" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016838
@@ -130747,6 +135908,8 @@
def: "Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate." [EC:4.2.3.-]
xref: EC:4.2.3.-
is_a: GO:0016835 ! carbon-oxygen lyase activity
+property_value: skos:exactMatch EC:4.2.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016839
@@ -130766,6 +135929,8 @@
synonym: "other carbon-nitrogen lyase activity" NARROW []
xref: EC:4.3.-.-
is_a: GO:0016829 ! lyase activity
+property_value: skos:exactMatch EC:4.3.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016841
@@ -130774,7 +135939,9 @@
def: "Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate." [GOC:krc]
xref: EC:4.3.1.-
is_a: GO:0016840 ! carbon-nitrogen lyase activity
+property_value: skos:exactMatch EC:4.3.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28259" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016842
@@ -130783,7 +135950,9 @@
def: "Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate." [GOC:krc]
xref: EC:4.3.2.-
is_a: GO:0016840 ! carbon-nitrogen lyase activity
+property_value: skos:exactMatch EC:4.3.2.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28259" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016843
@@ -130792,7 +135961,9 @@
def: "Catalysis of the release of amines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate." [GOC:krc]
xref: EC:4.3.3.-
is_a: GO:0016840 ! carbon-nitrogen lyase activity
+property_value: skos:exactMatch EC:4.3.3.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28259" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016844
@@ -130808,7 +135979,10 @@
xref: MetaCyc:STRICTOSIDINE-SYNTHASE-RXN
xref: RHEA:15013
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch EC:3.5.99.13
+property_value: skos:exactMatch RHEA:15013
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28647" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016845
@@ -130828,9 +136002,9 @@
synonym: "carbon-sulphur lyase activity" EXACT []
xref: EC:4.4.-.-
xref: Reactome:R-HSA-1614567 "Excess homocysteine yields homolanthionine and H2S"
-xref: Reactome:R-HSA-1614591 "Excess cysteine yields lanthionine and H2S"
-xref: Reactome:R-HSA-1614614 "Cysteine is degraded to pyruvate and H2S"
is_a: GO:0016829 ! lyase activity
+property_value: skos:exactMatch EC:4.4.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016847
@@ -130854,6 +136028,9 @@
xref: RHEA:21744
is_a: GO:0016846 ! carbon-sulfur lyase activity
relationship: part_of GO:0042218 ! 1-aminocyclopropane-1-carboxylate biosynthetic process
+property_value: skos:exactMatch EC:4.4.1.14
+property_value: skos:exactMatch RHEA:21744
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016848
@@ -130862,6 +136039,8 @@
def: "Catalysis of the breakage of a bond between carbon and any halogen atom." [GOC:mah]
xref: EC:4.5.-.-
is_a: GO:0016829 ! lyase activity
+property_value: skos:exactMatch EC:4.5.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016849
@@ -130870,7 +136049,10 @@
def: "Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond." [GOC:jl]
xref: EC:4.6.-.-
is_a: GO:0016829 ! lyase activity
+property_value: skos:exactMatch EC:4.6.-.-
+property_value: skos:relatedMatch EC:4.6.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016850
@@ -130901,7 +136083,10 @@
xref: MetaCyc:RXN1F-20
xref: RHEA:13961
is_a: GO:0051003 ! ligase activity, forming nitrogen-metal bonds, forming coordination complexes
+property_value: skos:exactMatch EC:6.6.1.1
+property_value: skos:exactMatch RHEA:13961
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23371" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016852
@@ -130916,6 +136101,9 @@
xref: MetaCyc:4.99.1.3-RXN
xref: RHEA:15893
is_a: GO:0016829 ! lyase activity
+property_value: skos:exactMatch EC:4.99.1.3
+property_value: skos:exactMatch RHEA:15893
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016853
@@ -130936,6 +136124,8 @@
xref: Reactome:R-HSA-2161735 "PGC2 is isomerised to PGB2"
xref: Reactome:R-HSA-6787623 "TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal"
is_a: GO:0003824 ! catalytic activity
+property_value: skos:exactMatch EC:5.-.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016854
@@ -130946,6 +136136,8 @@
synonym: "racemase and epimerase activity, acting on other compounds" NARROW []
xref: EC:5.1.-.-
is_a: GO:0016853 ! isomerase activity
+property_value: skos:exactMatch EC:5.1.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016855
@@ -130954,6 +136146,8 @@
def: "Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid." [GOC:mah]
xref: EC:5.1.1.-
is_a: GO:0016854 ! racemase and epimerase activity
+property_value: skos:exactMatch EC:5.1.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016856
@@ -130962,6 +136156,8 @@
def: "Catalysis of a reaction that alters the configuration of one or more chiral centers in a hydroxy acid molecule." [GOC:mah]
xref: EC:5.1.2.-
is_a: GO:0016854 ! racemase and epimerase activity
+property_value: skos:exactMatch EC:5.1.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016857
@@ -130971,6 +136167,8 @@
xref: EC:5.1.3.-
xref: Reactome:R-HSA-6787677 "FUOM isomerises alpha-Fuc to beta-Fuc"
is_a: GO:0016854 ! racemase and epimerase activity
+property_value: skos:exactMatch EC:5.1.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016858
@@ -130989,6 +136187,8 @@
def: "Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers." [GOC:mah, ISBN:0198506732]
xref: EC:5.2.-.-
is_a: GO:0016853 ! isomerase activity
+property_value: skos:exactMatch EC:5.2.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016860
@@ -131000,6 +136200,8 @@
xref: EC:5.3.-.-
xref: Reactome:R-HSA-109998 "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA"
is_a: GO:0016853 ! isomerase activity
+property_value: skos:exactMatch EC:5.3.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016861
@@ -131009,6 +136211,8 @@
synonym: "intramolecular isomerase activity, interconverting aldoses and ketoses" EXACT []
xref: EC:5.3.1.-
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:exactMatch EC:5.3.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016862
@@ -131018,6 +136222,8 @@
synonym: "intramolecular isomerase activity, interconverting keto- and enol-groups" EXACT []
xref: EC:5.3.2.-
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:exactMatch EC:5.3.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016863
@@ -131026,8 +136232,9 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears." [EC:5.3.3.-, GOC:mah]
synonym: "intramolecular isomerase activity, transposing C=C bonds" EXACT []
xref: EC:5.3.3.-
-xref: Reactome:R-HSA-2161563 "PGJ2 is isomerised to delta12-PGJ2"
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:exactMatch EC:5.3.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016864
@@ -131037,6 +136244,8 @@
synonym: "intramolecular isomerase activity, transposing S-S bonds" EXACT []
xref: EC:5.3.4.-
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:exactMatch EC:5.3.4.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016865
@@ -131058,6 +136267,8 @@
synonym: "mutase activity" EXACT []
xref: EC:5.4.-.-
is_a: GO:0016853 ! isomerase activity
+property_value: skos:exactMatch EC:5.4.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016867
@@ -131067,7 +136278,9 @@
synonym: "intramolecular transferase activity, transferring acyl groups" EXACT []
xref: EC:5.4.1.-
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26155" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016868
@@ -131080,7 +136293,9 @@
synonym: "phosphotransferase activity, with regeneration of donors, apparently catalyzing intramolecular transfers" EXACT []
xref: EC:5.4.2.-
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.2.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26155" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016869
@@ -131090,7 +136305,9 @@
synonym: "intramolecular transferase activity, transferring amino groups" EXACT []
xref: EC:5.4.3.-
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.3.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26155" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016870
@@ -131118,6 +136335,9 @@
xref: MetaCyc:CYCLOARTENOL-SYNTHASE-RXN
xref: RHEA:21308
is_a: GO:0031559 ! oxidosqualene cyclase activity
+property_value: skos:exactMatch EC:5.4.99.8
+property_value: skos:exactMatch RHEA:21308
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016872
@@ -131126,6 +136346,8 @@
def: "The catalysis of certain rearrangements of a molecule to break or form a ring." [GOC:jl]
xref: EC:5.5.1.-
is_a: GO:0016853 ! isomerase activity
+property_value: skos:exactMatch EC:5.5.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016873
@@ -131154,7 +136376,9 @@
synonym: "synthetase activity" EXACT [GOC:jh2]
xref: EC:6.-.-.-
is_a: GO:0003824 ! catalytic activity
+property_value: skos:exactMatch EC:6.-.-.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19380" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016875
@@ -131163,6 +136387,8 @@
def: "Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6.1.-.-]
xref: EC:6.1.-.-
is_a: GO:0016874 ! ligase activity
+property_value: skos:exactMatch EC:6.1.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016877
@@ -131172,6 +136398,8 @@
synonym: "ligase activity, forming carbon-sulphur bonds" EXACT []
xref: EC:6.2.-.-
is_a: GO:0016874 ! ligase activity
+property_value: skos:exactMatch EC:6.2.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016878
@@ -131180,6 +136408,8 @@
def: "Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6.2.1.-, GOC:mah]
xref: EC:6.2.1.-
is_a: GO:0016877 ! ligase activity, forming carbon-sulfur bonds
+property_value: skos:exactMatch EC:6.2.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016879
@@ -131189,6 +136419,8 @@
synonym: "other carbon-nitrogen ligase activity" NARROW []
xref: EC:6.3.-.-
is_a: GO:0016874 ! ligase activity
+property_value: skos:exactMatch EC:6.3.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016880
@@ -131198,6 +136430,8 @@
synonym: "amide synthase activity" EXACT []
xref: EC:6.3.1.-
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016881
@@ -131207,6 +136441,8 @@
synonym: "peptide synthase activity" EXACT []
xref: EC:6.3.2.-
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016882
@@ -131215,7 +136451,9 @@
def: "Catalysis of the joining of two groups within a single molecule via a carbon-nitrogen bond, forming heterocyclic ring, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [GOC:jl, GOC:mah]
xref: EC:6.3.3.-
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.3.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23224" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016883
@@ -131235,7 +136473,9 @@
def: "Catalysis of the transfer of the amide nitrogen of glutamine to a substrate. Usually composed of two subunits or domains, one that first hydrolyzes glutamine, and then transfers the resulting ammonia to the second subunit (or domain), where it acts as a source of nitrogen." [PMID:12360532]
xref: EC:6.3.5.-
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.5.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16422" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016885
@@ -131244,6 +136484,8 @@
def: "Catalysis of the joining of two molecules via a carbon-carbon bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6.4.-.-]
xref: EC:6.4.-.-
is_a: GO:0016874 ! ligase activity
+property_value: skos:exactMatch EC:6.4.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016886
@@ -131252,6 +136494,8 @@
def: "Catalysis of the joining of two molecules, or two groups within a single molecule, via a phosphoric ester bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6.5.-.-]
xref: EC:6.5.-.-
is_a: GO:0016874 ! ligase activity
+property_value: skos:exactMatch EC:6.5.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016887
@@ -131287,16 +136531,15 @@
xref: Reactome:R-HSA-9668415 "VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope"
xref: Reactome:R-HSA-9706399 "RHOBTB3 hydrolyzes ATP"
xref: Reactome:R-HSA-9749350 "ATP-dependent release of CDT1 from the OCCM complex"
-xref: Reactome:R-HSA-9948300 "RQT complex:K63polyUb-80S ribosome dissociates yielding K63polyUb-40S subunit and 60S subunit:peptidyl-tRNA with nascent peptide"
-xref: Reactome:R-HSA-9949632 "VCP hexamer extracts K48 polyubiquitinated alanine-tailed nascent peptide from VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:K48polyUb-nascent peptide"
-xref: Reactome:R-HSA-9955731 "ABCE1:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide dissociates yielding ABCE1:40S ribosomal subunit, PELO, and 60S ribosomal subunit:peptidyl-tRNA with nascent peptide"
xref: RHEA:13065
is_a: GO:0017111 ! ribonucleoside triphosphate phosphatase activity
relationship: part_of GO:0140657 ! ATP-dependent activity
+property_value: skos:exactMatch RHEA:13065
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19078" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20498" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21612" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22371" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016888
@@ -131309,7 +136552,9 @@
xref: Reactome:R-HSA-912368 "SPO11 hydrolyzes DNA forming double-strand breaks"
is_a: GO:0004520 ! DNA endonuclease activity
is_a: GO:0016788 ! hydrolase activity, acting on ester bonds
+property_value: skos:exactMatch EC:3.1.21.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016889
@@ -131321,7 +136566,9 @@
xref: EC:3.1.22.-
is_a: GO:0004520 ! DNA endonuclease activity
is_a: GO:0016788 ! hydrolase activity, acting on ester bonds
+property_value: skos:exactMatch EC:3.1.22.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016890
@@ -131343,7 +136590,9 @@
xref: EC:3.1.26.-
is_a: GO:0004521 ! RNA endonuclease activity
is_a: GO:0016788 ! hydrolase activity, acting on ester bonds
+property_value: skos:exactMatch EC:3.1.26.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016892
@@ -131357,6 +136606,7 @@
xref: Reactome:R-HSA-9755252 "nsp15 cleaves viral poly(U)-RNA"
is_a: GO:0004521 ! RNA endonuclease activity
is_a: GO:0016788 ! hydrolase activity, acting on ester bonds
+property_value: skos:exactMatch EC:3.1.27.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
[Term]
@@ -131395,7 +136645,9 @@
synonym: "exonuclease VIII activity" NARROW []
xref: EC:3.1.11.-
is_a: GO:0004529 ! DNA exonuclease activity
+property_value: skos:exactMatch EC:3.1.11.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016896
@@ -131407,7 +136659,9 @@
xref: EC:3.1.13.-
xref: Reactome:R-HSA-429860 "DCP1-DCP2 complex decaps mRNA"
is_a: GO:0004532 ! RNA exonuclease activity
+property_value: skos:exactMatch EC:3.1.13.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016897
@@ -131426,6 +136680,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a cytochrome molecule." [GOC:ai]
xref: EC:1.1.2.-
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.2.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016899
@@ -131434,6 +136690,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule." [GOC:ai]
xref: EC:1.1.3.-
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016900
@@ -131452,6 +136710,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule." [EC:1.1.5.-, GOC:ai]
xref: EC:1.1.5.-
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.5.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016902
@@ -131471,6 +136731,8 @@
synonym: "oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors" NARROW []
xref: EC:1.2.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.2.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016905
@@ -131493,6 +136755,10 @@
xref: EC:2.7.11.7
xref: RHEA:11424
is_a: GO:0004683 ! calcium/calmodulin-dependent protein kinase activity
+property_value: skos:exactMatch EC:2.7.11.7
+property_value: skos:exactMatch RHEA:11424
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0016906
@@ -131513,9 +136779,28 @@
synonym: "uridine diphosphoglucose-poriferasterol glucosyltransferase activity" RELATED [EC:2.4.1.173]
synonym: "uridine diphosphoglucose-sterol glucosyltransferase activity" RELATED [EC:2.4.1.173]
xref: EC:2.4.1.173
+xref: MetaCyc:RXN-12123
+xref: MetaCyc:RXN-12125
+xref: MetaCyc:RXN-12126
+xref: MetaCyc:RXN-12127
+xref: MetaCyc:RXN-12128
+xref: MetaCyc:RXN-16975
+xref: MetaCyc:RXN-8875
+xref: MetaCyc:RXN-8882
xref: MetaCyc:STEROL-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:22724
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.173
+property_value: skos:exactMatch MetaCyc:STEROL-GLUCOSYLTRANSFERASE-RXN
+property_value: skos:exactMatch RHEA:22724
+property_value: skos:narrowMatch MetaCyc:RXN-12123
+property_value: skos:narrowMatch MetaCyc:RXN-12125
+property_value: skos:narrowMatch MetaCyc:RXN-12126
+property_value: skos:narrowMatch MetaCyc:RXN-12127
+property_value: skos:narrowMatch MetaCyc:RXN-12128
+property_value: skos:narrowMatch MetaCyc:RXN-16975
+property_value: skos:narrowMatch MetaCyc:RXN-8875
+property_value: skos:narrowMatch MetaCyc:RXN-8882
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25771" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -131663,8 +136948,12 @@
name: pyroglutamyl-peptidase activity
namespace: molecular_function
def: "Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein." [GOC:mah, PMID:9920379]
+xref: EC:3.4.19.3
+xref: EC:3.4.19.6
is_a: GO:0008234 ! cysteine-type peptidase activity
is_a: GO:0008242 ! omega peptidase activity
+property_value: skos:narrowMatch EC:3.4.19.3
+property_value: skos:narrowMatch EC:3.4.19.6
[Term]
id: GO:0016921
@@ -131802,8 +137091,16 @@
xref: EC:1.3.8.1
xref: KEGG_REACTION:R01178
xref: MetaCyc:RXN-13449
+xref: RHEA:24004
xref: RHEA:47196
+xref: UM-BBD_reactionID:r0013
is_a: GO:0003995 ! acyl-CoA dehydrogenase activity
+property_value: skos:exactMatch EC:1.3.8.1
+property_value: skos:exactMatch KEGG_REACTION:R01178
+property_value: skos:exactMatch MetaCyc:RXN-13449
+property_value: skos:exactMatch RHEA:47196
+property_value: skos:narrowMatch RHEA:24004
+property_value: skos:narrowMatch UM-BBD_reactionID:r0013
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23273" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25073" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
@@ -131931,6 +137228,9 @@
xref: MetaCyc:NITRIC-OXIDE-REDUCTASE-RXN
xref: RHEA:30211
is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.7.2.5
+property_value: skos:exactMatch RHEA:30211
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016969
@@ -131961,7 +137261,9 @@
xref: RHEA:59116
is_a: GO:0015035 ! protein-disulfide reductase activity
is_a: GO:0016972 ! thiol oxidase activity
+property_value: skos:exactMatch RHEA:59116
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25461" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016972
@@ -131976,7 +137278,10 @@
xref: UM-BBD_reactionID:r1293
is_a: GO:0015036 ! disulfide oxidoreductase activity
is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.8.3.2
+property_value: skos:exactMatch RHEA:17357
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25462" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016973
@@ -132010,6 +137315,8 @@
xref: EC:3.2.1.132
xref: MetaCyc:3.2.1.132-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.132
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016979
@@ -132024,10 +137331,17 @@
synonym: "lipoate-protein ligase B activity" NARROW []
xref: EC:6.3.1.20
xref: MetaCyc:RXN-17127
+xref: MetaCyc:RXN0-1141
+xref: MetaCyc:RXN0-5098
xref: RHEA:49288
is_a: GO:0016779 ! nucleotidyltransferase activity
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:6.3.1.20
+property_value: skos:exactMatch MetaCyc:RXN-17127
+property_value: skos:exactMatch RHEA:49288
+property_value: skos:narrowMatch MetaCyc:RXN0-1141
+property_value: skos:narrowMatch MetaCyc:RXN0-5098
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -132041,6 +137355,9 @@
xref: MetaCyc:CREATINASE-RXN
xref: RHEA:22456
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.3
+property_value: skos:exactMatch RHEA:22456
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016984
@@ -132064,6 +137381,8 @@
xref: MetaCyc:RIBULOSE-BISPHOSPHATE-CARBOXYLASE-RXN
xref: RHEA:23124
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.39
+property_value: skos:exactMatch RHEA:23124
[Term]
id: GO:0016985
@@ -132082,6 +137401,8 @@
xref: EC:3.2.1.78
xref: MetaCyc:3.2.1.78-RXN
is_a: GO:0004567 ! beta-mannosidase activity
+property_value: skos:exactMatch EC:3.2.1.78
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016986
@@ -132151,13 +137472,16 @@
xref: MetaCyc:ARGININE-DEIMINASE-RXN
xref: RHEA:19597
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.6
+property_value: skos:exactMatch RHEA:19597
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016992
name: lipoate synthase activity
namespace: molecular_function
alt_id: GO:0017140
-def: "Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl." [EC:2.8.1.8, PMID:18307109]
+def: "Catalysis of the reaction: [[Fe-S] cluster scaffold protein carrying a second [4Fe-4S]2+ cluster] + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine + 4 H+ = [[Fe-S] cluster scaffold protein] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 4 Fe3+ + 2 hydrogen sulfide + 2 5'-deoxyadenosine + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]." [RHEA:16585]
synonym: "LipA" RELATED [EC:2.8.1.8]
synonym: "lipoic acid synthase" EXACT [GOC:dph, GOC:tb]
synonym: "lipoyl synthase activity" RELATED [EC:2.8.1.8]
@@ -132165,12 +137489,22 @@
synonym: "protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase activity" RELATED [EC:2.8.1.8]
synonym: "protein N6-(octanoyl)lysine:sulfur sulfurtransferase activity" RELATED [EC:2.8.1.8]
xref: EC:2.8.1.8
+xref: MetaCyc:RXN-14950
+xref: MetaCyc:RXN-14957
+xref: MetaCyc:RXN-14959
xref: MetaCyc:RXN0-949
xref: Reactome:R-HSA-6793591 "LIAS synthesizes lipoyl-GCSH"
xref: RHEA:16585
is_a: GO:0016783 ! sulfurtransferase activity
relationship: part_of GO:0009107 ! lipoate biosynthetic process
+property_value: skos:exactMatch EC:2.8.1.8
+property_value: skos:exactMatch MetaCyc:RXN0-949
+property_value: skos:exactMatch RHEA:16585
+property_value: skos:narrowMatch MetaCyc:RXN-14950
+property_value: skos:narrowMatch MetaCyc:RXN-14957
+property_value: skos:narrowMatch MetaCyc:RXN-14959
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30187" xsd:anyURI
[Term]
id: GO:0016993
@@ -132185,6 +137519,9 @@
xref: MetaCyc:5.4.1.2-RXN
xref: RHEA:22512
is_a: GO:0016867 ! intramolecular acyltransferase activity
+property_value: skos:exactMatch EC:5.4.99.61
+property_value: skos:exactMatch RHEA:22512
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016994
@@ -132199,6 +137536,9 @@
xref: MetaCyc:1.3.1.54-RXN
xref: RHEA:23408
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.54
+property_value: skos:exactMatch RHEA:23408
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016995
@@ -132215,6 +137555,9 @@
xref: MetaCyc:CHOLESTEROL-OXIDASE-RXN
xref: RHEA:32183
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.6
+property_value: skos:exactMatch RHEA:32183
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016996
@@ -132232,6 +137575,8 @@
xref: EC:3.2.1.129
xref: MetaCyc:3.2.1.129-RXN
is_a: GO:0016997 ! alpha-sialidase activity
+property_value: skos:exactMatch EC:3.2.1.129
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0016997
@@ -132439,6 +137784,7 @@
xref: Reactome:R-HSA-390593 "ATP Hydrolysis By Myosin"
xref: Reactome:R-HSA-445699 "ATP Hydrolysis By Myosin"
is_a: GO:0004722 ! protein serine/threonine phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.16
[Term]
id: GO:0017020
@@ -132599,9 +137945,11 @@
xref: Reactome:R-HSA-1606602 "ASAH1 hydrolyzes ceramide"
xref: Reactome:R-HSA-428205 "ACER2 hydrolyzes ceramide (Golgi)"
xref: Reactome:R-HSA-428231 "ACER1 hydrolyzes ceramide (endoplasmic reticulum)"
-xref: Reactome:R-HSA-428262 "ACER3 hydrolyzes phytoceramide"
xref: RHEA:20856
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.23
+property_value: skos:exactMatch MetaCyc:CERAMIDASE-RXN
+property_value: skos:exactMatch RHEA:20856
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27364" xsd:anyURI
[Term]
@@ -132629,6 +137977,8 @@
synonym: "glycosyl-N-acylsphingosine glycohydrolase activity" RELATED [EC:3.2.1.62]
xref: MetaCyc:GLYCOSYLCERAMIDASE-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:broadMatch EC:3.2.1.62
+property_value: skos:exactMatch MetaCyc:GLYCOSYLCERAMIDASE-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22611" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25793" xsd:anyURI
@@ -132670,7 +138020,6 @@
namespace: molecular_function
def: "Binding to a peptide with hormonal activity in animals." [GOC:jl, ISBN:0198506732]
synonym: "polypeptide hormone binding" EXACT []
-is_a: GO:0033218 ! amide binding
is_a: GO:0042562 ! hormone binding
[Term]
@@ -132680,6 +138029,8 @@
def: "OBSOLETE. Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP." [RHEA:35847]
comment: This term was obsoleted because it represents a specific substrate of sphingosine kinase activity ; GO:0008481.
synonym: "sphingosine kinase activity" BROAD []
+xref: Reactome:R-HSA-5218845 "p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate"
+xref: Reactome:R-HSA-9625814 "SPHK1 phosphorylates sphingosine in response to E2 stimulation"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30243" xsd:anyURI
is_obsolete: true
replaced_by: GO:0008481
@@ -132754,8 +138105,7 @@
synonym: "nuclear pore activity" RELATED []
synonym: "nucleocytoplasmic transporter activity" EXACT []
xref: Reactome:R-HSA-1176059 "Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus"
-xref: Reactome:R-HSA-170796 "NPC transports GCK1:GCKR from cytosol to nucleoplasm"
-xref: Reactome:R-HSA-170825 "NPC exports GCK1 from nucleus"
+xref: Reactome:R-HSA-170796 "NPC transports GCK1:GKRP from cytosol to nucleoplasm"
xref: Reactome:R-HSA-192627 "Viral mRNA Export"
xref: Reactome:R-HSA-192925 "Export of Spliced Viral mRNA"
xref: Reactome:R-HSA-5252041 "NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm"
@@ -132781,9 +138131,12 @@
xref: EC:3.1.1.31
xref: KEGG_REACTION:R02035
xref: MetaCyc:6PGLUCONOLACT-RXN
-xref: Reactome:R-HSA-71296 "PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate"
+xref: Reactome:R-HSA-71296 "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate"
xref: RHEA:12556
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.31
+property_value: skos:exactMatch RHEA:12556
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017058
@@ -132841,7 +138194,12 @@
xref: Reactome:R-HSA-5693925 "FUT3 transfers L-fucose to Gal1,3GlcNAc"
xref: Reactome:R-HSA-9603986 "FUT3 transfers Fuc to Type 1 chains to form LeA"
xref: RHEA:23628
+xref: RHEA:48824
is_a: GO:0008417 ! fucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.65
+property_value: skos:exactMatch RHEA:23628
+property_value: skos:narrowMatch RHEA:48824
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30384" xsd:anyURI
[Term]
@@ -132864,6 +138222,9 @@
xref: Reactome:R-HSA-1237160 "MTA is cleaved and phosphorylated"
xref: RHEA:11852
is_a: GO:0004731 ! purine-nucleoside phosphorylase activity
+property_value: skos:exactMatch EC:2.4.2.28
+property_value: skos:exactMatch RHEA:11852
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017062
@@ -132899,9 +138260,18 @@
synonym: "anandamide amidohydrolase activity" NARROW []
synonym: "oleamide hydrolase activity" NARROW []
xref: EC:3.5.1.99
+xref: MetaCyc:RXN-10756
+xref: MetaCyc:RXN6666-2
xref: Reactome:R-HSA-5693742 "FAAH hydrolyses AEA to AA and ETA"
xref: Reactome:R-HSA-5693751 "FAAH2 hydrolyses AEA to AA and ETA"
+xref: RHEA:26136
+xref: RHEA:26506
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.99
+property_value: skos:narrowMatch MetaCyc:RXN-10756
+property_value: skos:narrowMatch MetaCyc:RXN6666-2
+property_value: skos:narrowMatch RHEA:26136
+property_value: skos:narrowMatch RHEA:26506
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23420" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -132930,6 +138300,9 @@
xref: MetaCyc:TYROSINE-ESTER-SULFOTRANSFERASE-RXN
xref: RHEA:19977
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.9
+property_value: skos:exactMatch RHEA:19977
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017069
@@ -133019,9 +138392,6 @@
synonym: "Hsc70 protein regulator activity" EXACT []
is_obsolete: true
replaced_by: GO:0031072
-consider: GO:0006457
-consider: GO:0051082
-consider: GO:0051787
[Term]
id: GO:0017080
@@ -133067,6 +138437,9 @@
xref: MetaCyc:GALACTOSIDE-3-FUCOSYLTRANSFERASE-RXN
xref: RHEA:14257
is_a: GO:0046920 ! alpha-(1->3)-fucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.152
+property_value: skos:exactMatch RHEA:14257
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017084
@@ -133077,6 +138450,8 @@
xref: Reactome:R-HSA-508040 "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]"
xref: RHEA:33207
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:33207
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017085
@@ -133192,6 +138567,7 @@
xref: Reactome:R-HSA-2076419 "HS6STs sulfate GlcN at C6 in heparan sulfate/heparin"
xref: RHEA:56604
is_a: GO:0034483 ! heparan sulfate sulfotransferase activity
+property_value: skos:exactMatch RHEA:56604
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24749" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28380" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28762" xsd:anyURI
@@ -133212,6 +138588,9 @@
xref: RHEA:15573
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.4
+property_value: skos:exactMatch RHEA:15573
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017098
@@ -133235,6 +138614,9 @@
xref: Reactome:R-HSA-548831 "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA"
xref: RHEA:19181
is_a: GO:0003995 ! acyl-CoA dehydrogenase activity
+property_value: skos:exactMatch EC:1.3.8.9
+property_value: skos:exactMatch MetaCyc:RXN-13451
+property_value: skos:exactMatch RHEA:19181
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23273" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23497" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
@@ -133280,6 +138662,9 @@
xref: MetaCyc:UTPHEXPURIDYLYLTRANS-RXN
xref: RHEA:14209
is_a: GO:0051748 ! UTP-monosaccharide-1-phosphate uridylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.10
+property_value: skos:exactMatch RHEA:14209
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017105
@@ -133301,9 +138686,12 @@
xref: MetaCyc:1.14.99.32-RXN
xref: RHEA:25852
is_a: GO:0016215 ! acyl-CoA desaturase activity
+property_value: skos:exactMatch EC:1.14.19.5
+property_value: skos:exactMatch RHEA:25852
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22050" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24103" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29820" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017106
@@ -133335,7 +138723,6 @@
xref: Reactome:R-HSA-5651782 "FEN1 bound to POLB cleaves displaced DNA strand (flap)"
xref: Reactome:R-HSA-5687664 "FEN1 cleaves displaced ssDNA flaps during MMEJ"
xref: Reactome:R-HSA-69152 "Removal of remaining Flap"
-xref: Reactome:R-HSA-9914870 "MGME1 cleaves 5' DNA flap from nascent mitochondrial DNA"
is_a: GO:0016888 ! DNA endonuclease activity, producing 5'-phosphomonoesters
is_a: GO:0048256 ! flap endonuclease activity
@@ -133375,7 +138762,10 @@
xref: Reactome:R-HSA-8851550 "NTPDase8 hydrolyzes nucleoside diphosphates"
xref: RHEA:36799
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.6
+property_value: skos:exactMatch RHEA:36799
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017111
@@ -133403,8 +138793,11 @@
xref: Reactome:R-HSA-8851538 "NTPDase8 hydrolyzes nucleoside triphosphates"
xref: RHEA:23680
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.15
+property_value: skos:exactMatch RHEA:23680
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21232" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017113
@@ -133428,6 +138821,9 @@
xref: Reactome:R-HSA-73616 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+"
xref: RHEA:18093
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.2
+property_value: skos:exactMatch RHEA:18093
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017114
@@ -133467,6 +138863,8 @@
def: "Catalysis of the reaction: (R)-lipoyl-5'-AMP + L-lysyl-[lipoyl-carrier protein] = (R)-N6-lipoyl-L-lysyl-[lipoyl-carrier protein] + AMP + 2 H+." [PMID:10103005, RHEA:20473]
xref: RHEA:20473
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch RHEA:20473
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017119
@@ -133637,6 +139035,7 @@
synonym: "sirtuin" NARROW []
is_a: GO:0004407 ! histone deacetylase activity
is_a: GO:0034979 ! NAD-dependent protein lysine deacetylase activity
+property_value: skos:broadMatch EC:2.3.1.286
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22836" xsd:anyURI
[Term]
@@ -133747,10 +139146,16 @@
name: tRNA dihydrouridine synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: a 5,6-dihydrouridine in tRNA + NAD(P)+ = a uridine in tRNA + H+ + NAD(P)H." [PMID:11983710, PMID:22123979]
+xref: MetaCyc:RXN0-1281
xref: Reactome:R-HSA-6782296 "DUS2:EPRS reduces uridine to dihydrouridine in tRNAs"
+xref: RHEA:23624
+xref: RHEA:54452
is_a: GO:0106413 ! RNA dihydrouridine synthase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
relationship: part_of GO:0002943 ! tRNA dihydrouridine synthesis
+property_value: skos:narrowMatch MetaCyc:RXN0-1281
+property_value: skos:narrowMatch RHEA:23624
+property_value: skos:narrowMatch RHEA:54452
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25790" xsd:anyURI
[Term]
@@ -133833,6 +139238,9 @@
xref: Reactome:R-HSA-8938300 "Vanin hydrolyses pantetheine to PanK, 2AET"
xref: RHEA:13445
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.92
+property_value: skos:exactMatch RHEA:13445
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017161
@@ -133842,6 +139250,8 @@
xref: Reactome:R-HSA-1855180 "I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol"
xref: RHEA:43392
is_a: GO:0046030 ! inositol trisphosphate phosphatase activity
+property_value: skos:exactMatch RHEA:43392
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017162
@@ -133920,6 +139330,9 @@
xref: RHEA:10348
xref: Wikipedia:5-oxoprolinase_(ATP-hydrolysing)
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.9
+property_value: skos:exactMatch RHEA:10348
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017169
@@ -133955,6 +139368,9 @@
xref: Reactome:R-HSA-1614645 "CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine"
xref: RHEA:20441
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.20
+property_value: skos:exactMatch RHEA:20441
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017174
@@ -133972,7 +139388,10 @@
xref: RHEA:19937
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.20
+property_value: skos:exactMatch RHEA:19937
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25505" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017175
@@ -133997,6 +139416,9 @@
xref: MetaCyc:2.4.1.198-RXN
xref: RHEA:14789
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.198
+property_value: skos:exactMatch RHEA:14789
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017177
@@ -134023,6 +139445,9 @@
xref: Reactome:R-HSA-5358475 "DPH6 ligates ammonium to diphthine-EEF2"
xref: RHEA:19753
is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity
+property_value: skos:exactMatch EC:6.3.1.14
+property_value: skos:exactMatch RHEA:19753
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017179
@@ -134140,9 +139565,12 @@
xref: EC:2.3.1.17
xref: KEGG_REACTION:R00487
xref: MetaCyc:ASPARTATE-N-ACETYLTRANSFERASE-RXN
-xref: Reactome:R-HSA-8954468 "NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP"
+xref: Reactome:R-HSA-8954468 "NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA"
xref: RHEA:14165
is_a: GO:0140085 ! L-amino-acid N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.17
+property_value: skos:exactMatch RHEA:14165
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0017189
@@ -134479,6 +139907,9 @@
xref: Reactome:R-HSA-6786205 "KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1"
xref: RHEA:21556
is_a: GO:0016279 ! protein-lysine N-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.60
+property_value: skos:exactMatch RHEA:21556
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018026
@@ -134860,7 +140291,10 @@
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0008276 ! protein methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.85
+property_value: skos:exactMatch RHEA:19369
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26174" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018065
@@ -135064,12 +140498,12 @@
[Term]
id: GO:0018085
-name: peptidyl-L-amino acid racemization
+name: obsolete peptidyl-L-amino acid racemization
namespace: biological_process
-def: "The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid." [GOC:ma]
-subset: gocheck_do_not_annotate
-is_a: GO:0018193 ! peptidyl-amino acid modification
-is_a: GO:0018366 ! chiral amino acid racemization
+def: "OBSOLETE. The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid." [GOC:ma]
+comment: The reason for obsoletion is that this term represents a molecular function.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31180" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0018086
@@ -135080,7 +140514,6 @@
comment: This term was made obsolete because it was replaced with more appropriate terms.
synonym: "alanine racemization" EXACT []
is_obsolete: true
-consider: GO:0019122
[Term]
id: GO:0018091
@@ -135243,6 +140676,9 @@
xref: MetaCyc:METHIONINE-RACEMASE-RXN
xref: RHEA:12492
is_a: GO:0047661 ! amino-acid racemase activity
+property_value: skos:exactMatch EC:5.1.1.2
+property_value: skos:exactMatch RHEA:12492
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018112
@@ -135254,6 +140690,9 @@
xref: MetaCyc:PROLINE-RACEMASE-RXN
xref: RHEA:10680
is_a: GO:0047661 ! amino-acid racemase activity
+property_value: skos:exactMatch EC:5.1.1.4
+property_value: skos:exactMatch RHEA:10680
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018113
@@ -135264,6 +140703,9 @@
xref: MetaCyc:LYSINE-RACEMASE-RXN
xref: RHEA:22864
is_a: GO:0047661 ! amino-acid racemase activity
+property_value: skos:exactMatch EC:5.1.1.5
+property_value: skos:exactMatch RHEA:22864
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018114
@@ -135275,6 +140717,9 @@
xref: MetaCyc:THREONINE-RACEMASE-RXN
xref: RHEA:13913
is_a: GO:0047661 ! amino-acid racemase activity
+property_value: skos:exactMatch EC:5.1.1.6
+property_value: skos:exactMatch RHEA:13913
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018115
@@ -135426,10 +140871,12 @@
[Term]
id: GO:0018129
-name: peptidyl-oxazoline dehydrogenase activity
+name: obsolete peptidyl-oxazoline dehydrogenase activity
namespace: molecular_function
-def: "Catalysis of the reduction of a peptide-linked oxazoline to oxazole." [GOC:mah, PMID:19058272]
-is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+def: "OBSOLETE. Catalysis of the reduction of a peptide-linked oxazoline to oxazole." [GOC:mah, PMID:19058272]
+comment: The reason for obsoletion is that it is not known to be catalyzed by any gene product.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30921" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0018130
@@ -135495,10 +140942,12 @@
[Term]
id: GO:0018136
-name: peptidyl-thiazoline dehydrogenase activity
+name: obsolete peptidyl-thiazoline dehydrogenase activity
namespace: molecular_function
-def: "Catalysis of the reduction of a peptide-linked thiazoline to thiazole." [GOC:mah, PMID:19058272]
-is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+def: "OBSOLETE. Catalysis of the reduction of a peptide-linked thiazoline to thiazole." [GOC:mah, PMID:19058272]
+comment: The reason for obsoletion is that it is not known to be catalyzed by any gene product.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30921" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0018137
@@ -136793,6 +142242,15 @@
def: "OBSOLETE. Catalysis of the reaction: ATP + biotin + protein = AMP + diphosphate + biotin-protein." [GOC:mah]
comment: The reason for obsoletion is this term is an unnecessary grouping term.
synonym: "biotin-apoprotein ligase activity" EXACT []
+xref: Reactome:R-HSA-2993447 "HLCS biotinylates 6x(PCCA:PCCB)"
+xref: Reactome:R-HSA-2993799 "HLCS biotinylates 6xMCCC1:6xMCCC2"
+xref: Reactome:R-HSA-2993802 "HLCS biotinylates PC:Mn2+"
+xref: Reactome:R-HSA-2993814 "HLCS biotinylates ACACA:Mn2+"
+xref: Reactome:R-HSA-3323184 "Defective HLCS does not biotinylate ACACA:Mn2+"
+xref: Reactome:R-HSA-4167511 "HLCS biotinylates ACACB"
+xref: Reactome:R-HSA-9035987 "Defective HLCS does not biotinylate 6xMCCC1:6xMCCC2"
+xref: Reactome:R-HSA-9035988 "Defective HLCS does not biotinylate PC:Mn2+"
+xref: Reactome:R-HSA-9035990 "Defective HLCS does not biotinylate 6x(PCCA:PCCB)"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28107" xsd:anyURI
is_obsolete: true
replaced_by: GO:0004077
@@ -136866,14 +142324,17 @@
[Term]
id: GO:0018279
-name: protein N-linked glycosylation via asparagine
+name: obsolete protein N-linked glycosylation via asparagine
namespace: biological_process
-def: "The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification." [GOC:jsg]
+def: "OBSOLETE. The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification." [GOC:jsg]
+comment: The reason for obsoletion is that this term is equivalent to protein N-linked glycosylation.
synonym: "protein amino acid N-linked glycosylation via asparagine" EXACT [GOC:bf]
xref: Reactome:R-HSA-162699 "Synthesis of dolichyl-phosphate mannose"
xref: Reactome:R-HSA-446203 "Asparagine N-linked glycosylation"
xref: Reactome:R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose"
-is_a: GO:0006487 ! protein N-linked glycosylation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30880" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0006487
[Term]
id: GO:0018280
@@ -137671,13 +143132,18 @@
xref: MetaCyc:5.1.1.16-RXN
xref: RHEA:10660
is_a: GO:0016855 ! racemase and epimerase activity, acting on amino acids and derivatives
+property_value: skos:exactMatch EC:5.1.1.16
+property_value: skos:exactMatch RHEA:10660
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018366
-name: chiral amino acid racemization
+name: obsolete chiral amino acid racemization
namespace: biological_process
-def: "The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid." [GOC:jsg, ISBN:0198506732]
-is_a: GO:0006520 ! amino acid metabolic process
+def: "OBSOLETE. The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid." [GOC:jsg, ISBN:0198506732]
+comment: The reason for obsoletion is that this term represents a molecular function.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31180" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0018367
@@ -137808,6 +143274,9 @@
xref: RHEA:24444
is_a: GO:0046920 ! alpha-(1->3)-fucosyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.214
+property_value: skos:exactMatch RHEA:24444
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018393
@@ -138101,9 +143570,15 @@
def: "Catalysis of the reaction: S-adenosyl-L-methionine + [protein]-L-leucine = S-adenosyl-L-homocysteine + [protein]-L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein." [PMID:8514774]
synonym: "protein phosphatase methyltransferase activity" NARROW []
synonym: "protein-leucine O-methyltransferase activity" EXACT []
+xref: EC:2.1.1.233
+xref: MetaCyc:RXN-12317
xref: Reactome:R-HSA-8856945 "PP2A methylation by LCMT1"
+xref: RHEA:48544
is_a: GO:0003880 ! protein C-terminal carboxyl O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:narrowMatch EC:2.1.1.233
+property_value: skos:narrowMatch MetaCyc:RXN-12317
+property_value: skos:narrowMatch RHEA:48544
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27556" xsd:anyURI
[Term]
@@ -138264,7 +143739,10 @@
xref: RHEA:28198
xref: UM-BBD_reactionID:r0032
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.1.311
+property_value: skos:exactMatch RHEA:28198
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27656" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018450
@@ -138294,6 +143772,9 @@
xref: RHEA:32879
xref: UM-BBD_reactionID:r0427
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.327
+property_value: skos:exactMatch RHEA:32879
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018453
@@ -138323,7 +143804,10 @@
xref: RHEA:22256
xref: UM-BBD_reactionID:r0202
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.36
+property_value: skos:exactMatch RHEA:22256
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25814" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018455
@@ -138332,7 +143816,11 @@
def: "Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde or ketone + NAD(P)H + H+." [GOC:curators]
synonym: "alcohol:NAD(P)+ oxidoreductase activity" RELATED [EC:1.1.1.71]
synonym: "aldehyde reductase (NADPH/NADH)" RELATED [EC:1.1.1.71]
+xref: EC:1.1.1.71
+xref: MetaCyc:ALCOHOL-DEHYDROGENASE-NADP+-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:narrowMatch EC:1.1.1.71
+property_value: skos:narrowMatch MetaCyc:ALCOHOL-DEHYDROGENASE-NADP+-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28532" xsd:anyURI
[Term]
@@ -138347,7 +143835,10 @@
xref: MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-RXN
xref: RHEA:12076
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.90
+property_value: skos:exactMatch RHEA:12076
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018457
@@ -138363,7 +143854,10 @@
xref: RHEA:10664
xref: UM-BBD_reactionID:r0729
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.144
+property_value: skos:exactMatch RHEA:10664
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018458
@@ -138377,6 +143871,9 @@
xref: RHEA:20860
xref: UM-BBD_reactionID:r0740
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.223
+property_value: skos:exactMatch RHEA:20860
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018459
@@ -138391,6 +143888,9 @@
xref: RHEA:13629
xref: UM-BBD_reactionID:r0714
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.243
+property_value: skos:exactMatch RHEA:13629
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018460
@@ -138403,6 +143903,9 @@
xref: RHEA:10044
xref: UM-BBD_reactionID:r0165
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.245
+property_value: skos:exactMatch RHEA:10044
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018461
@@ -138415,6 +143918,8 @@
xref: MetaCyc:9-FLUORENOL-DEHYDROGENASE-RXN
xref: UM-BBD_reactionID:r0408
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.256
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018462
@@ -138430,6 +143935,9 @@
xref: RHEA:24412
xref: UM-BBD_reactionID:r0291
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.257
+property_value: skos:exactMatch RHEA:24412
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018463
@@ -138443,6 +143951,9 @@
xref: RHEA:14225
xref: UM-BBD_reactionID:r0174
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.258
+property_value: skos:exactMatch RHEA:14225
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018464
@@ -138456,6 +143967,9 @@
xref: RHEA:11168
xref: UM-BBD_reactionID:r0196
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.259
+property_value: skos:exactMatch RHEA:11168
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018465
@@ -138470,6 +143984,9 @@
xref: RHEA:10036
xref: UM-BBD_reactionID:r0651
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.38
+property_value: skos:exactMatch RHEA:10036
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018466
@@ -138493,6 +144010,9 @@
xref: RHEA:16425
xref: UM-BBD_reactionID:r0240
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.46
+property_value: skos:exactMatch RHEA:16425
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018469
@@ -138549,7 +144069,10 @@
xref: RHEA:27298
xref: UM-BBD_reactionID:r0490
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.78
+property_value: skos:exactMatch RHEA:27298
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28056" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018475
@@ -138573,6 +144096,9 @@
xref: UM-BBD_enzymeID:r0214
xref: UM-BBD_enzymeID:r0222
is_a: GO:0033721 ! aldehyde dehydrogenase (NADP+) activity
+property_value: skos:exactMatch EC:1.2.1.7
+property_value: skos:exactMatch RHEA:21660
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018478
@@ -138583,8 +144109,14 @@
synonym: "malonic semialdehyde oxidative decarboxylase activity" EXACT []
xref: EC:1.2.1.18
xref: MetaCyc:RXN-9958
+xref: RHEA:22988
+xref: RHEA:22992
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.18
+property_value: skos:narrowMatch RHEA:22988
+property_value: skos:narrowMatch RHEA:22992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25817" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018479
@@ -138598,6 +144130,9 @@
xref: RHEA:11840
xref: UM-BBD_reactionID:r0269
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.28
+property_value: skos:exactMatch RHEA:11840
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018480
@@ -138611,6 +144146,9 @@
xref: RHEA:15681
xref: UM-BBD_reactionID:r0365
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.60
+property_value: skos:exactMatch RHEA:15681
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018481
@@ -138624,6 +144162,9 @@
xref: RHEA:22420
xref: UM-BBD_reactionID:r0229
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.61
+property_value: skos:exactMatch RHEA:22420
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018482
@@ -138639,6 +144180,9 @@
xref: RHEA:18833
xref: UM-BBD_reactionID:r0292
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.62
+property_value: skos:exactMatch RHEA:18833
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018483
@@ -138651,6 +144195,9 @@
xref: RHEA:13397
xref: UM-BBD_reactionID:r0175
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.63
+property_value: skos:exactMatch RHEA:13397
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018484
@@ -138665,6 +144212,9 @@
xref: RHEA:20305
xref: UM-BBD_reactionID:r0273
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.64
+property_value: skos:exactMatch RHEA:20305
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018485
@@ -138677,6 +144227,9 @@
xref: RHEA:18537
xref: UM-BBD_enzymeID:r0339
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.65
+property_value: skos:exactMatch RHEA:18537
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018486
@@ -138704,9 +144257,17 @@
synonym: "aryl-aldehyde:oxygen oxidoreductase activity" RELATED [EC:1.2.3.9]
xref: EC:1.2.3.9
xref: MetaCyc:ARYL-ALDEHYDE-OXIDASE-RXN
+xref: MetaCyc:RXN-8089
+xref: MetaCyc:RXN-8090
+xref: MetaCyc:RXN-8091
xref: RHEA:18569
xref: UM-BBD_reactionID:r0145
is_a: GO:0004031 ! aldehyde oxidase activity
+property_value: skos:exactMatch EC:1.2.3.9
+property_value: skos:exactMatch RHEA:18569
+property_value: skos:narrowMatch MetaCyc:RXN-8089
+property_value: skos:narrowMatch MetaCyc:RXN-8090
+property_value: skos:narrowMatch MetaCyc:RXN-8091
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -138726,7 +144287,10 @@
xref: UM-BBD_reactionID:r0146
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
is_a: GO:0032451 ! demethylase activity
+property_value: skos:exactMatch EC:1.14.13.82
+property_value: skos:exactMatch RHEA:13021
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018490
@@ -138740,6 +144304,9 @@
xref: RHEA:17197
xref: UM-BBD_reactionID:r0299
is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.2.3.13
+property_value: skos:exactMatch RHEA:17197
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018491
@@ -138755,6 +144322,8 @@
xref: RHEA:32135
xref: UM-BBD_reactionID:r0358
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:32135
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018492
@@ -138780,6 +144349,9 @@
xref: RHEA:19841
xref: UM-BBD_reactionID:r0345
is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors
+property_value: skos:exactMatch EC:1.2.7.12
+property_value: skos:exactMatch RHEA:19841
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018494
@@ -138787,8 +144359,17 @@
namespace: molecular_function
def: "Catalysis of the reactions: (1R,4R)-dihydrocarvone + A = (R)-carvone + AH2, and (1R,4S)-isodihydrocarvone + A = (S)-carvone + AH2." [EC:1.3.99.25]
xref: EC:1.3.99.25
+xref: MetaCyc:RXN-9403
+xref: MetaCyc:RXN-9419
+xref: RHEA:32423
+xref: RHEA:32427
xref: UM-BBD_reactionID:r0732
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.99.25
+property_value: skos:narrowMatch MetaCyc:RXN-9403
+property_value: skos:narrowMatch MetaCyc:RXN-9419
+property_value: skos:narrowMatch RHEA:32423
+property_value: skos:narrowMatch RHEA:32427
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -138826,9 +144407,15 @@
def: "Catalysis of the reaction: 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+ = 3-(2,3-dihydroxyphenyl)propanoate + H+ + NADH. Also converts (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate to (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate." [EC:1.3.1.87]
xref: EC:1.3.1.87
xref: MetaCyc:PHENPRODIOLDEHYDROG-RXN
+xref: RHEA:25062
+xref: RHEA:25066
xref: UM-BBD_enzymeID:r0436
xref: UM-BBD_enzymeID:r1620
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.87
+property_value: skos:narrowMatch RHEA:25062
+property_value: skos:narrowMatch RHEA:25066
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018499
@@ -138866,6 +144453,8 @@
xref: RHEA:15741
xref: UM-BBD_reactionID:r0553
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:15741
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018503
@@ -138889,6 +144478,9 @@
xref: RHEA:15457
xref: UM-BBD_enzymeID:r0080
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.19
+property_value: skos:exactMatch RHEA:15457
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018505
@@ -138905,6 +144497,9 @@
xref: MetaCyc:1.3.1.29-RXN
xref: RHEA:11832
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.29
+property_value: skos:exactMatch RHEA:11832
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018506
@@ -138917,6 +144512,8 @@
xref: MetaCyc:MALEYLACETATE-REDUCTASE-RXN
xref: UM-BBD_enzymeID:r0099
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.32
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018507
@@ -138931,6 +144528,9 @@
xref: RHEA:16253
xref: UM-BBD_reactionID:r0488
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.49
+property_value: skos:exactMatch RHEA:16253
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018508
@@ -138956,6 +144556,9 @@
xref: RHEA:17033
xref: UM-BBD_enzymeID:r0389
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.56
+property_value: skos:exactMatch RHEA:17033
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018510
@@ -138969,6 +144572,9 @@
xref: RHEA:10080
xref: UM-BBD_reactionID:r0007
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.57
+property_value: skos:exactMatch RHEA:10080
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018511
@@ -138982,6 +144588,9 @@
xref: RHEA:23772
xref: UM-BBD_reactionID:r0396
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.58
+property_value: skos:exactMatch RHEA:23772
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018512
@@ -139005,6 +144614,9 @@
xref: RHEA:24188
xref: UM-BBD_reactionID:r0161
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.60
+property_value: skos:exactMatch RHEA:24188
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018515
@@ -139018,6 +144630,9 @@
xref: RHEA:19665
xref: UM-BBD_reactionID:r0194
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.62
+property_value: skos:exactMatch RHEA:19665
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018516
@@ -139031,7 +144646,10 @@
xref: RHEA:23076
xref: UM-BBD_reactionID:r0138
is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond
+property_value: skos:exactMatch EC:1.21.1.2
+property_value: skos:exactMatch RHEA:23076
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018517
@@ -139045,6 +144663,9 @@
xref: RHEA:13837
xref: UM-BBD_reactionID:r0142
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.64
+property_value: skos:exactMatch RHEA:13837
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018518
@@ -139059,6 +144680,9 @@
xref: RHEA:24556
xref: UM-BBD_reactionID:r0053
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.65
+property_value: skos:exactMatch RHEA:24556
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018519
@@ -139073,6 +144697,9 @@
xref: RHEA:18101
xref: UM-BBD_reactionID:r0309
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.66
+property_value: skos:exactMatch RHEA:18101
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018520
@@ -139085,6 +144712,8 @@
xref: MetaCyc:1.3.1.67-RXN
xref: UM-BBD_reactionID:r0179
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.67
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018521
@@ -139098,6 +144727,9 @@
xref: RHEA:15657
xref: UM-BBD_reactionID:r0224
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.68
+property_value: skos:exactMatch RHEA:15657
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018522
@@ -139112,6 +144744,9 @@
xref: RHEA:30199
xref: UM-BBD_reactionID:r0190
is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.3.7.8
+property_value: skos:exactMatch RHEA:30199
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018523
@@ -139124,6 +144759,9 @@
xref: RHEA:17749
xref: UM-BBD_reactionID:r0045
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.99.17
+property_value: skos:exactMatch RHEA:17749
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018524
@@ -139148,6 +144786,9 @@
xref: RHEA:29603
xref: UM-BBD_reactionID:r0158
is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.1.7.1
+property_value: skos:exactMatch RHEA:29603
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018526
@@ -139169,6 +144810,9 @@
xref: RHEA:18433
xref: UM-BBD_reactionID:r0754
is_a: GO:0008131 ! primary methylamine oxidase activity
+property_value: skos:exactMatch EC:1.4.3.12
+property_value: skos:exactMatch RHEA:18433
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018528
@@ -139190,6 +144834,8 @@
xref: RHEA:31359
xref: UM-BBD_reactionID:r0587
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.10
+property_value: skos:exactMatch RHEA:31359
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -139206,7 +144852,10 @@
xref: RHEA:10012
xref: UM-BBD_reactionID:r0477
is_a: GO:0019116 ! hydroxy-nicotine oxidase activity
+property_value: skos:exactMatch EC:1.5.3.6
+property_value: skos:exactMatch RHEA:10012
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018531
@@ -139223,6 +144872,9 @@
xref: RHEA:11880
xref: UM-BBD_reactionID:r0478
is_a: GO:0019116 ! hydroxy-nicotine oxidase activity
+property_value: skos:exactMatch EC:1.5.3.5
+property_value: skos:exactMatch RHEA:11880
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018532
@@ -139270,6 +144922,9 @@
xref: UM-BBD_enzymeID:r0978
xref: UM-BBD_enzymeID:r0979
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.99.4
+property_value: skos:exactMatch RHEA:14769
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018537
@@ -139293,6 +144948,9 @@
xref: RHEA:21144
xref: UM-BBD_reactionID:r0354
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.98.2
+property_value: skos:exactMatch RHEA:21144
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018538
@@ -139314,6 +144972,9 @@
xref: MetaCyc:1.6.5.6-RXN
xref: RHEA:23488
is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.6.5.6
+property_value: skos:exactMatch RHEA:23488
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018542
@@ -139361,9 +145022,14 @@
def: "Catalysis of the reaction: H2O + N-phenylhydroxylamine + 2 NADP+ = 2 H+ + 2 NADPH + nitrobenzene." [PMID:16517619, RHEA:52884]
xref: EC:1.7.1.16
xref: MetaCyc:RXN-8815
+xref: MetaCyc:RXN-8833
xref: RHEA:52884
xref: UM-BBD_enzymeID:r0303
is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.7.1.16
+property_value: skos:exactMatch MetaCyc:RXN-8815
+property_value: skos:exactMatch RHEA:52884
+property_value: skos:narrowMatch MetaCyc:RXN-8833
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23357" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -139374,6 +145040,7 @@
def: "OBSOLETE. Catalysis of the removal of one or more nitrite (NO2-) groups from nitroglycerin or a derivative." [GOC:curators]
comment: This term was obsoleted because there is no evidence that this specific reaction exists.
synonym: "NG reductase activity" EXACT []
+xref: Reactome:R-HSA-9620103 "ALDH2 transforms GTN to NO"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28261" xsd:anyURI
is_obsolete: true
@@ -139401,6 +145068,9 @@
xref: RHEA:11812
xref: UM-BBD_reactionID:r0209
is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.8.3.4
+property_value: skos:exactMatch RHEA:11812
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018550
@@ -139422,8 +145092,11 @@
xref: MetaCyc:RXN-17803
xref: RHEA:78943
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:exactMatch EC:1.8.1.22
+property_value: skos:exactMatch RHEA:78943
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25448" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28006" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018553
@@ -139444,6 +145117,9 @@
xref: UM-BBD_enzymeID:r0336
is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
is_a: GO:0051213 ! dioxygenase activity
+property_value: skos:exactMatch EC:1.13.11.56
+property_value: skos:exactMatch RHEA:27310
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018555
@@ -139535,9 +145211,15 @@
synonym: "carbazole 1,9alpha-dioxygenase activity" EXACT []
synonym: "CARDO" EXACT [EC:1.14.12.22]
xref: EC:1.14.12.22
+xref: RHEA:27838
+xref: RHEA:27842
xref: UM-BBD_reactionID:r0456
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.22
+property_value: skos:narrowMatch RHEA:27838
+property_value: skos:narrowMatch RHEA:27842
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28050" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018565
@@ -139595,6 +145277,9 @@
xref: RHEA:42344
xref: UM-BBD_reactionID:r0395
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.14.12.25
+property_value: skos:exactMatch RHEA:42344
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018571
@@ -139607,6 +145292,8 @@
xref: RHEA:42568
xref: UM-BBD_reactionID:r0397
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch RHEA:42568
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018572
@@ -139663,6 +145350,8 @@
xref: RHEA:23852
xref: UM-BBD_enzymeID:r0601
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.1
+property_value: skos:exactMatch RHEA:23852
[Term]
id: GO:0018577
@@ -139681,6 +145370,8 @@
xref: RHEA:17337
xref: UM-BBD_enzymeID:r0307
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.2
+property_value: skos:exactMatch RHEA:17337
[Term]
id: GO:0018578
@@ -139697,6 +145388,9 @@
xref: RHEA:10084
xref: UM-BBD_reactionID:r0143
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.3
+property_value: skos:exactMatch RHEA:10084
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018579
@@ -139712,6 +145406,9 @@
xref: RHEA:24044
xref: UM-BBD_reactionID:r0144
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.8
+property_value: skos:exactMatch RHEA:24044
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018580
@@ -139725,6 +145422,9 @@
xref: MetaCyc:2-NITROPROPANE-DIOXYGENASE-RXN
xref: RHEA:28767
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
+property_value: skos:exactMatch EC:1.13.12.16
+property_value: skos:exactMatch RHEA:28767
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018581
@@ -139735,7 +145435,10 @@
xref: RHEA:19441
xref: UM-BBD_reactionID:r0232
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:broadMatch EC:1.13.11.37
+property_value: skos:exactMatch RHEA:19441
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25870" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018582
@@ -139751,6 +145454,9 @@
xref: RHEA:14749
xref: UM-BBD_reactionID:r0486
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.38
+property_value: skos:exactMatch RHEA:14749
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018583
@@ -139766,6 +145472,9 @@
xref: RHEA:14413
xref: UM-BBD_enzymeID:r0390
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.39
+property_value: skos:exactMatch RHEA:14413
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018584
@@ -139851,8 +145560,13 @@
namespace: molecular_function
def: "Catalysis of the reaction: 4-nitrocatechol + NAD(P)H + O2 = 2-hydroxy-1,4-benzoquinone + nitrite + NAD(P)+ + H2O." [EC:1.14.13.166]
xref: EC:1.14.13.166
+xref: RHEA:34307
+xref: RHEA:34311
xref: UM-BBD_reactionID:r0231
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.166
+property_value: skos:narrowMatch RHEA:34307
+property_value: skos:narrowMatch RHEA:34311
[Term]
id: GO:0018593
@@ -139904,6 +145618,9 @@
xref: RHEA:27341
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.39
+property_value: skos:exactMatch RHEA:27341
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018598
@@ -139947,6 +145664,9 @@
xref: RHEA:12568
xref: UM-BBD_reactionID:r0230
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.29
+property_value: skos:exactMatch RHEA:12568
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018602
@@ -139957,6 +145677,8 @@
xref: RHEA:48984
xref: UM-BBD_reactionID:r0274
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch RHEA:48984
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018603
@@ -140022,6 +145744,8 @@
xref: RHEA:42460
xref: UM-BBD_enzymeID:r0026
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch RHEA:42460
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018611
@@ -140106,6 +145830,8 @@
xref: MetaCyc:1.14.12.1-RXN
xref: UM-BBD_reactionID:r0577
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.1
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018619
@@ -140121,6 +145847,9 @@
xref: RHEA:13813
xref: UM-BBD_reactionID:r0079
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.3
+property_value: skos:exactMatch RHEA:13813
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018620
@@ -140136,6 +145865,9 @@
xref: RHEA:17489
xref: UM-BBD_reactionID:r0102
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.7
+property_value: skos:exactMatch RHEA:17489
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018621
@@ -140152,6 +145884,9 @@
xref: RHEA:13937
xref: UM-BBD_reactionID:r0293
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.8
+property_value: skos:exactMatch RHEA:13937
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018622
@@ -140165,6 +145900,9 @@
xref: RHEA:14689
xref: UM-BBD_reactionID:r0308
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.9
+property_value: skos:exactMatch RHEA:14689
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018623
@@ -140181,6 +145919,9 @@
xref: RHEA:12633
xref: UM-BBD_enzymeID:r0245
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.10
+property_value: skos:exactMatch RHEA:12633
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018624
@@ -140196,6 +145937,9 @@
xref: RHEA:16737
xref: UM-BBD_enzymeID:r0253
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.11
+property_value: skos:exactMatch RHEA:16737
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018625
@@ -140210,6 +145954,9 @@
xref: RHEA:19173
xref: UM-BBD_enzymeID:r0334
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.12
+property_value: skos:exactMatch RHEA:19173
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018626
@@ -140222,7 +145969,10 @@
xref: MetaCyc:RXN-13706
xref: RHEA:53736
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.13
+property_value: skos:exactMatch RHEA:53736
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30179" xsd:anyURI
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[Term]
id: GO:0018627
@@ -140241,6 +145991,9 @@
xref: RHEA:23468
xref: UM-BBD_reactionID:r0218
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.14
+property_value: skos:exactMatch RHEA:23468
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[Term]
id: GO:0018628
@@ -140256,6 +146009,9 @@
xref: RHEA:10312
xref: UM-BBD_reactionID:r0150
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[Term]
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@@ -140271,6 +146027,9 @@
xref: RHEA:10976
xref: UM-BBD_reactionID:r0052
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
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[Term]
id: GO:0018630
@@ -140291,7 +146050,10 @@
xref: RHEA:53392
xref: UM-BBD_reactionID:r0036
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.54
+property_value: skos:exactMatch RHEA:53392
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27862" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018632
@@ -140303,6 +146065,9 @@
xref: RHEA:34327
xref: UM-BBD_reactionID:r0226
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.167
+property_value: skos:exactMatch RHEA:34327
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[Term]
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@@ -140314,7 +146079,10 @@
xref: RHEA:31355
xref: UM-BBD_reactionID:r0208
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.131
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property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27862" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018634
@@ -140326,8 +146094,11 @@
xref: RHEA:32891
xref: UM-BBD_reactionID:r0742
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.155
+property_value: skos:exactMatch RHEA:32891
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26207" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018635
@@ -140355,9 +146126,15 @@
namespace: molecular_function
def: "Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NAD(P)H + 2 H+ = NAD(P)+ + H2O + CO2 + 1,2-dihydroxynaphthalene." [EC:1.14.13.135, PMID:20727010, PMID:21545490, UM-BBD_reactionID:r0491]
xref: EC:1.14.13.135
+xref: RHEA:31271
+xref: RHEA:31571
xref: UM-BBD_reactionID:r0491
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.135
+property_value: skos:narrowMatch RHEA:31271
+property_value: skos:narrowMatch RHEA:31571
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26102" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018638
@@ -140368,6 +146145,9 @@
xref: RHEA:41380
xref: UM-BBD_enzymeID:r0255
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.236
+property_value: skos:exactMatch RHEA:41380
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018639
@@ -140382,12 +146162,17 @@
id: GO:0018640
name: dibenzothiophene monooxygenase activity
namespace: molecular_function
-def: "Catalysis of the reaction: dibenzothiophene + FMNH2 + O2 = dibenzothiophene 5-oxide + FMN + H2O + H+." [RHEA:49076]
+def: "Catalysis of the reaction: dibenzothiophene + 2 FMNH2 + 2 O2 = dibenzothiophene 5,5-dioxide + 2 FMN + 2 H2O + 2 H+." [RHEA:49076]
+xref: EC:1.14.14.21
xref: MetaCyc:RXN-621
xref: RHEA:49076
xref: UM-BBD_enzymeID:r0037
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.21
+property_value: skos:exactMatch MetaCyc:RXN-621
+property_value: skos:exactMatch RHEA:49076
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30522" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0018641
@@ -140427,6 +146212,9 @@
xref: RHEA:20349
xref: UM-BBD_enzymeID:r0260
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.243
+property_value: skos:exactMatch RHEA:20349
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018645
@@ -140441,6 +146229,9 @@
xref: UM-BBD_enzymeID:r0856
xref: UM-BBD_enzymeID:r0857
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.69
+property_value: skos:exactMatch RHEA:11792
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018646
@@ -140477,6 +146268,9 @@
xref: MetaCyc:RXN-9770
xref: RHEA:26077
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.111
+property_value: skos:exactMatch RHEA:26077
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018649
@@ -140516,6 +146310,8 @@
xref: RHEA:51024
xref: UM-BBD_reactionID:r0290
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:51024
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018653
@@ -140580,6 +146376,9 @@
xref: RHEA:11004
xref: UM-BBD_enzymeID:r0340
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.1
+property_value: skos:exactMatch RHEA:11004
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018659
@@ -140600,6 +146399,8 @@
xref: MetaCyc:4-HYDROXYBENZOATE-3-MONOOXYGENASE-RXN
xref: UM-BBD_reactionID:r0109
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.2
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018660
@@ -140628,6 +146429,9 @@
xref: RHEA:19601
xref: UM-BBD_reactionID:r0092
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.6
+property_value: skos:exactMatch RHEA:19601
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018662
@@ -140642,6 +146446,9 @@
xref: RHEA:17061
xref: UM-BBD_enzymeID:r0696
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.7
+property_value: skos:exactMatch RHEA:17061
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018663
@@ -140656,6 +146463,9 @@
xref: RHEA:16917
xref: UM-BBD_reactionID:r0479
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.10
+property_value: skos:exactMatch RHEA:16917
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018664
@@ -140676,6 +146486,9 @@
xref: RHEA:18033
xref: UM-BBD_reactionID:r0623
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.92
+property_value: skos:exactMatch RHEA:18033
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018665
@@ -140689,8 +146502,14 @@
synonym: "4-hydroxyphenylacetic 1-hydroxylase activity" RELATED [EC:1.14.13.18]
xref: EC:1.14.13.18
xref: MetaCyc:1.14.13.18-RXN
+xref: RHEA:15157
+xref: RHEA:15161
xref: UM-BBD_reactionID:r0300
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.18
+property_value: skos:narrowMatch RHEA:15157
+property_value: skos:narrowMatch RHEA:15161
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[Term]
id: GO:0018666
@@ -140705,6 +146524,9 @@
xref: RHEA:20920
xref: UM-BBD_enzymeID:r0275
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.20
+property_value: skos:exactMatch RHEA:20920
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018667
@@ -140720,6 +146542,9 @@
xref: RHEA:24068
xref: UM-BBD_reactionID:r0166
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.22
+property_value: skos:exactMatch RHEA:24068
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018668
@@ -140734,6 +146559,9 @@
xref: RHEA:11480
xref: UM-BBD_reactionID:r0153
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.23
+property_value: skos:exactMatch RHEA:11480
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018669
@@ -140750,6 +146578,9 @@
xref: RHEA:22692
xref: UM-BBD_reactionID:r0402
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.24
+property_value: skos:exactMatch RHEA:22692
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018670
@@ -140764,6 +146595,8 @@
xref: MetaCyc:4-AMINOBENZOATE-1-MONOOXYGENASE-RXN
xref: UM-BBD_reactionID:r0597
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.27
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018671
@@ -140777,6 +146610,8 @@
xref: EC:1.14.13.33
xref: MetaCyc:1.14.13.33-RXN
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.33
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018672
@@ -140794,6 +146629,9 @@
xref: RHEA:21236
xref: UM-BBD_reactionID:r0578
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.35
+property_value: skos:exactMatch RHEA:21236
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018673
@@ -140807,6 +146645,8 @@
xref: MetaCyc:ANTHRANILOYL-COA-MONOOXYGENASE-RXN
xref: UM-BBD_reactionID:r0568
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.40
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018674
@@ -140825,7 +146665,10 @@
xref: UM-BBD_reactionID:r0739
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
is_a: GO:0019113 ! limonene monooxygenase activity
+property_value: skos:exactMatch EC:1.14.14.99
+property_value: skos:exactMatch RHEA:15129
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27866" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018675
@@ -140843,7 +146686,10 @@
xref: UM-BBD_reactionID:r0713
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
is_a: GO:0019113 ! limonene monooxygenase activity
+property_value: skos:exactMatch EC:1.14.14.51
+property_value: skos:exactMatch RHEA:17945
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27866" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018676
@@ -140858,7 +146704,10 @@
xref: UM-BBD_reactionID:r0728
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
is_a: GO:0019113 ! limonene monooxygenase activity
+property_value: skos:exactMatch EC:1.14.14.52
+property_value: skos:exactMatch RHEA:23432
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27866" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018677
@@ -140879,6 +146728,9 @@
xref: RHEA:18685
xref: UM-BBD_enzymeID:r0313
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.50
+property_value: skos:exactMatch RHEA:18685
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018678
@@ -140891,6 +146743,8 @@
xref: MetaCyc:1.14.13.64-RXN
xref: UM-BBD_reactionID:r0752
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.64
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018679
@@ -140903,7 +146757,10 @@
xref: RHEA:12312
xref: UM-BBD_reactionID:r0235
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.22
+property_value: skos:exactMatch RHEA:12312
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28101" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018680
@@ -140956,10 +146813,13 @@
xref: RHEA:13525
xref: UM-BBD_enzymeID:r0426
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.15.1
+property_value: skos:exactMatch RHEA:13525
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018684
-name: 2,5-diketocamphane 1,2-monooxygenase
+name: 2,5-diketocamphane 1,2-monooxygenase activity
namespace: molecular_function
def: "Catalysis of the reaction: 1R,4R)-bornane-2,5-dione + FMNH2 + O2 = (1R,4R)-5-oxo-1,2-campholide + FMN + H+ + H2O." [PMID:3944058, PMID:8515237, RHEA:34415]
synonym: "(+)-camphor,reduced-rubredoxin:oxygen oxidoreductase (1,2-lactonizing)" RELATED []
@@ -140971,7 +146831,10 @@
xref: RHEA:34415
xref: UM-BBD_enzymeID:r0428
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.108
+property_value: skos:exactMatch RHEA:34415
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018685
@@ -140988,6 +146851,8 @@
xref: RHEA:19341
xref: UM-BBD_enzymeID:r0021
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:broadMatch EC:1.14.15.3
+property_value: skos:exactMatch RHEA:19341
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27756" xsd:anyURI
[Term]
@@ -141012,6 +146877,9 @@
xref: RHEA:18165
xref: UM-BBD_enzymeID:r0388
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.12.18
+property_value: skos:exactMatch RHEA:18165
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018688
@@ -141050,6 +146918,9 @@
xref: UM-BBD_reactionID:r0154
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.15
+property_value: skos:exactMatch RHEA:18613
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018693
@@ -141064,6 +146935,9 @@
xref: RHEA:17897
xref: UM-BBD_reactionID:r0234
is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups
+property_value: skos:exactMatch EC:1.17.99.2
+property_value: skos:exactMatch RHEA:17897
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018694
@@ -141075,6 +146949,9 @@
xref: RHEA:51604
xref: UM-BBD_reactionID:r0392
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.15.25
+property_value: skos:exactMatch RHEA:51604
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018695
@@ -141090,6 +146967,9 @@
xref: RHEA:15141
xref: UM-BBD_reactionID:r0272
is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups
+property_value: skos:exactMatch EC:1.17.9.1
+property_value: skos:exactMatch RHEA:15141
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018697
@@ -141112,7 +146992,9 @@
xref: RHEA:68004
xref: UM-BBD_reactionID:r0352
is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond
+property_value: skos:exactMatch RHEA:68004
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28112" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018699
@@ -141198,6 +147080,9 @@
xref: RHEA:21000
xref: UM-BBD_reactionID:r0006
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.97.1.2
+property_value: skos:exactMatch RHEA:21000
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018707
@@ -141222,6 +147107,9 @@
xref: RHEA:18277
is_a: GO:0008172 ! S-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.9
+property_value: skos:exactMatch RHEA:18277
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018710
@@ -141234,6 +147122,9 @@
xref: MetaCyc:6.4.1.6-RXN
xref: RHEA:18385
is_a: GO:0016885 ! ligase activity, forming carbon-carbon bonds
+property_value: skos:exactMatch EC:6.4.1.6
+property_value: skos:exactMatch RHEA:18385
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018711
@@ -141402,6 +147293,9 @@
xref: RHEA:23520
xref: UM-BBD_reactionID:r0087
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.1
+property_value: skos:exactMatch RHEA:23520
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018730
@@ -141414,6 +147308,9 @@
xref: RHEA:23208
xref: UM-BBD_reactionID:r0085
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.12
+property_value: skos:exactMatch RHEA:23208
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018731
@@ -141485,6 +147382,9 @@
xref: RHEA:14961
xref: UM-BBD_reactionID:r0241
is_a: GO:0016790 ! thiolester hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.12
+property_value: skos:exactMatch RHEA:14961
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018739
@@ -141499,6 +147399,9 @@
xref: RHEA:11948
xref: UM-BBD_reactionID:r0141
is_a: GO:0016289 ! acyl-CoA hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.23
+property_value: skos:exactMatch RHEA:11948
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018740
@@ -141524,6 +147427,9 @@
xref: RHEA:12945
xref: UM-BBD_enzymeID:r0236
is_a: GO:0046508 ! hydrolase activity, acting on carbon-sulfur bonds
+property_value: skos:exactMatch EC:3.13.1.3
+property_value: skos:exactMatch RHEA:12945
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018741
@@ -141535,7 +147441,10 @@
xref: RHEA:67908
xref: UM-BBD_reactionID:r0602
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.21
+property_value: skos:exactMatch RHEA:67908
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24319" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018742
@@ -141568,6 +147477,9 @@
xref: RHEA:10700
xref: UM-BBD_reactionID:r0734
is_a: GO:0004301 ! epoxide hydrolase activity
+property_value: skos:exactMatch EC:3.3.2.8
+property_value: skos:exactMatch RHEA:10700
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018745
@@ -141624,6 +147536,9 @@
xref: RHEA:17525
xref: UM-BBD_reactionID:r0846
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.84
+property_value: skos:exactMatch RHEA:17525
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018751
@@ -141653,7 +147568,10 @@
xref: RHEA:70363
xref: UM-BBD_reactionID:r0116
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.15
+property_value: skos:exactMatch RHEA:70363
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25982" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018754
@@ -141680,6 +147598,8 @@
xref: MetaCyc:RXN-8016
xref: RHEA:26201
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch RHEA:26201
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018757
@@ -141715,6 +147635,9 @@
xref: RHEA:19053
xref: UM-BBD_reactionID:r0347
is_a: GO:0019238 ! cyclohydrolase activity
+property_value: skos:exactMatch EC:3.5.4.27
+property_value: skos:exactMatch RHEA:19053
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018760
@@ -141728,6 +147651,9 @@
xref: RHEA:21464
xref: UM-BBD_reactionID:r0598
is_a: GO:0016815 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles
+property_value: skos:exactMatch EC:3.5.5.8
+property_value: skos:exactMatch RHEA:21464
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018761
@@ -141742,6 +147668,9 @@
xref: RHEA:22100
xref: UM-BBD_enzymeID:r0548
is_a: GO:0000257 ! nitrilase activity
+property_value: skos:exactMatch EC:3.5.5.6
+property_value: skos:exactMatch RHEA:22100
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018762
@@ -141754,6 +147683,9 @@
xref: RHEA:46188
xref: UM-BBD_reactionID:r0622
is_a: GO:0000257 ! nitrilase activity
+property_value: skos:exactMatch EC:3.5.5.7
+property_value: skos:exactMatch RHEA:46188
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018763
@@ -141769,6 +147701,9 @@
xref: RHEA:23092
xref: UM-BBD_enzymeID:r0114
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch EC:3.5.4.43
+property_value: skos:exactMatch RHEA:23092
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018764
@@ -141781,6 +147716,9 @@
xref: RHEA:23608
xref: UM-BBD_enzymeID:r0115
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch EC:3.5.4.42
+property_value: skos:exactMatch RHEA:23608
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018765
@@ -141791,7 +147729,9 @@
xref: MetaCyc:2-OH-6-OXOHEPTA-2-4-DIENOATE-HYDR-RXN
xref: RHEA:59220
xref: UM-BBD_reactionID:r0263
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.25
+property_value: skos:exactMatch RHEA:59220
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -141802,7 +147742,7 @@
xref: KEGG_REACTION:R07831
xref: MetaCyc:R6-RXN
xref: UM-BBD_reactionID:r0008
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
[Term]
id: GO:0018767
@@ -141822,8 +147762,11 @@
xref: MetaCyc:RXN-11543
xref: RHEA:27870
xref: UM-BBD_reactionID:r0458
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.13
+property_value: skos:exactMatch RHEA:27870
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018769
@@ -141854,7 +147797,9 @@
xref: MetaCyc:MHPCHYDROL-RXN
xref: RHEA:34187
xref: UM-BBD_reactionID:r0438
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:broadMatch EC:3.7.1.14
+property_value: skos:exactMatch RHEA:34187
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -141864,7 +147809,7 @@
def: "Catalysis of the reaction: 2,4,6-trioxoheptanoate + H2O = acetylpyruvate + acetate." [MetaCyc:R306-RXN, UM-BBD_reactionID:r0094]
xref: MetaCyc:R306-RXN
xref: UM-BBD_reactionID:r0094
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
[Term]
id: GO:0018773
@@ -141877,7 +147822,10 @@
xref: MetaCyc:ACETYLPYRUVATE-HYDROLASE-RXN
xref: RHEA:16097
xref: UM-BBD_reactionID:r0095
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.6
+property_value: skos:exactMatch RHEA:16097
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018774
@@ -141890,7 +147838,9 @@
xref: MetaCyc:3.7.1.8-RXN
xref: RHEA:17161
xref: UM-BBD_enzymeID:r0391
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:broadMatch EC:3.7.1.8
+property_value: skos:exactMatch RHEA:17161
[Term]
id: GO:0018775
@@ -141905,7 +147855,9 @@
xref: MetaCyc:3.7.1.9-RXN
xref: RHEA:14549
xref: UM-BBD_enzymeID:r1671
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.9
+property_value: skos:exactMatch RHEA:14549
[Term]
id: GO:0018776
@@ -142000,8 +147952,12 @@
xref: EC:3.8.1.2
xref: RHEA:11192
xref: UM-BBD_reactionID:r0090
-is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds
+is_a: GO:0019120 ! hydrolase activity, acting on halide bonds, in C-halide compounds
+property_value: skos:broadMatch MetaCyc:2-HALOACID-DEHALOGENASE-RXN
+property_value: skos:exactMatch EC:3.8.1.2
+property_value: skos:exactMatch RHEA:11192
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28188" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018785
@@ -142015,7 +147971,10 @@
xref: RHEA:11044
xref: UM-BBD_enzymeID:r0004
xref: UM-BBD_enzymeID:r1028
-is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds
+is_a: GO:0019120 ! hydrolase activity, acting on halide bonds, in C-halide compounds
+property_value: skos:exactMatch EC:3.8.1.3
+property_value: skos:exactMatch RHEA:11044
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018786
@@ -142028,8 +147987,13 @@
xref: EC:3.8.1.5
xref: MetaCyc:HALOALKANE-DEHALOGENASE-RXN
xref: RHEA:19081
+xref: RHEA:25185
xref: UM-BBD_enzymeID:r0001
-is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds
+is_a: GO:0019120 ! hydrolase activity, acting on halide bonds, in C-halide compounds
+property_value: skos:exactMatch EC:3.8.1.5
+property_value: skos:exactMatch RHEA:19081
+property_value: skos:narrowMatch RHEA:25185
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018787
@@ -142041,7 +148005,10 @@
xref: MetaCyc:3.8.1.7-RXN
xref: RHEA:14853
xref: UM-BBD_enzymeID:r0140
-is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds
+is_a: GO:0019120 ! hydrolase activity, acting on halide bonds, in C-halide compounds
+property_value: skos:exactMatch EC:3.8.1.7
+property_value: skos:exactMatch RHEA:14853
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018788
@@ -142054,7 +148021,10 @@
xref: MetaCyc:3.8.1.8-RXN
xref: RHEA:11312
xref: UM-BBD_reactionID:r0113
-is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds
+is_a: GO:0019120 ! hydrolase activity, acting on halide bonds, in C-halide compounds
+property_value: skos:exactMatch EC:3.8.1.8
+property_value: skos:exactMatch RHEA:11312
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018789
@@ -142071,7 +148041,10 @@
xref: MetaCyc:CYCLAMATE-SULFOHYDROLASE-RXN
xref: RHEA:18481
xref: UM-BBD_reactionID:r0755
-is_a: GO:0016826 ! hydrolase activity, acting on acid sulfur-nitrogen bonds
+is_a: GO:0016826 ! hydrolase activity, acting on sulfur-nitrogen bonds
+property_value: skos:exactMatch EC:3.10.1.2
+property_value: skos:exactMatch RHEA:18481
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018791
@@ -142131,6 +148104,9 @@
xref: RHEA:24184
xref: UM-BBD_enzymeID:r0149
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.55
+property_value: skos:exactMatch RHEA:24184
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018798
@@ -142146,6 +148122,9 @@
xref: RHEA:12749
xref: UM-BBD_reactionID:r0005
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.59
+property_value: skos:exactMatch RHEA:12749
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018799
@@ -142161,6 +148140,9 @@
xref: RHEA:10876
xref: UM-BBD_reactionID:r0159
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.61
+property_value: skos:exactMatch RHEA:10876
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018800
@@ -142179,12 +148161,15 @@
xref: RHEA:14397
xref: UM-BBD_reactionID:r0367
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.68
+property_value: skos:exactMatch RHEA:14397
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018801
name: glutaconyl-CoA decarboxylase activity
namespace: molecular_function
-def: "Catalysis of the reaction: trans-glutaconyl-CoA + H+ = but-2-enoyl-CoA + CO2." [PMID:11248185, RHEA:23972]
+def: "Catalysis of the reaction: (2E)-glutaconyl-CoA + Na+(in) + H+ = (2E)-butenoyl-CoA + Na+(out) + CO2." [PMID:11248185, RHEA:23972]
synonym: "4-carboxybut-2-enoyl-CoA carboxy-lyase (but-2-enoyl-CoA-forming)" EXACT []
synonym: "4-carboxybut-2-enoyl-CoA carboxy-lyase activity" RELATED [EC:7.2.4.5]
synonym: "glutaconyl coenzyme A decarboxylase activity" RELATED [EC:7.2.4.5]
@@ -142195,7 +148180,10 @@
xref: RHEA:23972
xref: UM-BBD_reactionID:r0199
is_a: GO:0015451 ! decarboxylation-driven active transmembrane transporter activity
-is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:7.2.4.5
+property_value: skos:exactMatch RHEA:23972
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31104" xsd:anyURI
[Term]
id: GO:0018802
@@ -142210,7 +148198,7 @@
id: GO:0018803
name: 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity
namespace: molecular_function
-def: "Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate." [EC:4.1.2.34]
+def: "Catalysis of the reaction: (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H2O = 2-formylbenzoate + pyruvate." [RHEA:16453]
synonym: "(3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity" NARROW [EC:4.1.2.34]
synonym: "(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase (pyruvate-forming)" RELATED [EC:4.1.2.34]
synonym: "(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity" NARROW [EC:4.1.2.34]
@@ -142220,7 +148208,11 @@
xref: MetaCyc:4.1.2.34-RXN
xref: RHEA:16453
xref: UM-BBD_reactionID:r0487
-is_a: GO:0016831 ! carboxy-lyase activity
+is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.34
+property_value: skos:exactMatch RHEA:16453
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31104" xsd:anyURI
[Term]
id: GO:0018805
@@ -142235,6 +148227,9 @@
xref: RHEA:10416
xref: UM-BBD_enzymeID:r0328
is_a: GO:0016830 ! carbon-carbon lyase activity
+property_value: skos:exactMatch EC:4.1.99.11
+property_value: skos:exactMatch RHEA:10416
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018807
@@ -142244,7 +148239,10 @@
xref: EC:3.7.1.21
xref: RHEA:39651
xref: UM-BBD_reactionID:r0204
-is_a: GO:0016822 ! hydrolase activity, acting on acid carbon-carbon bonds
+is_a: GO:0016822 ! hydrolase activity, acting on carbon-carbon bonds
+property_value: skos:exactMatch EC:3.7.1.21
+property_value: skos:exactMatch RHEA:39651
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018808
@@ -142287,6 +148285,9 @@
name: 3-hydroxyacyl-CoA dehydratase activity
namespace: molecular_function
def: "Catalysis of the reaction: a 3-hydroxy-fatty acyl-CoA = a (2E)-enoyl-CoA + H2O." [RHEA:33767]
+xref: EC:4.2.1.150
+xref: EC:4.2.1.74
+xref: MetaCyc:ENOYL-COA-HYDRAT-RXN
xref: Reactome:R-HSA-2066778 "Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA"
xref: Reactome:R-HSA-2066780 "Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA"
xref: Reactome:R-HSA-389986 "trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA"
@@ -142294,8 +148295,18 @@
xref: Reactome:R-HSA-5676637 "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA"
xref: Reactome:R-HSA-6809263 "EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA"
xref: Reactome:R-HSA-8957389 "RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA"
+xref: RHEA:16105
xref: RHEA:33767
+xref: RHEA:52664
+xref: RHEA:71647
is_a: GO:0004300 ! enoyl-CoA hydratase activity
+property_value: skos:exactMatch RHEA:33767
+property_value: skos:narrowMatch EC:4.2.1.150
+property_value: skos:narrowMatch EC:4.2.1.74
+property_value: skos:narrowMatch MetaCyc:ENOYL-COA-HYDRAT-RXN
+property_value: skos:narrowMatch RHEA:16105
+property_value: skos:narrowMatch RHEA:52664
+property_value: skos:narrowMatch RHEA:71647
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24738" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28557" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29788" xsd:anyURI
@@ -142304,11 +148315,15 @@
id: GO:0018813
name: trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde)." [UM-BBD_enzymeID:r0338]
+def: "Catalysis of the reaction: (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O = salicylaldehyde + pyruvate. A broad range of aldehydes and 4-substituted 2-oxobut-3-enoates are accepted as substrates." [EC:4.1.2.45, RHEA:27389]
xref: EC:4.1.2.45
xref: RHEA:27389
xref: UM-BBD_enzymeID:r0338
-is_a: GO:0016836 ! hydro-lyase activity
+is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.45
+property_value: skos:exactMatch RHEA:27389
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31104" xsd:anyURI
[Term]
id: GO:0018814
@@ -142324,7 +148339,10 @@
xref: RHEA:20069
xref: UM-BBD_reactionID:r0697
is_a: GO:0141122 ! nitrogen-oxygen lyase activity
+property_value: skos:exactMatch EC:4.8.1.4
+property_value: skos:exactMatch RHEA:20069
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24927" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018815
@@ -142356,6 +148374,8 @@
xref: RHEA:42072
xref: UM-BBD_reactionID:r0369
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch RHEA:42072
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018818
@@ -142371,6 +148391,9 @@
xref: RHEA:17885
xref: UM-BBD_reactionID:r0591
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.112
+property_value: skos:exactMatch RHEA:17885
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018819
@@ -142388,6 +148411,9 @@
xref: RHEA:34691
xref: UM-BBD_reactionID:r0086
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.54
+property_value: skos:exactMatch MetaCyc:LACTOYL-COA-DEHYDRATASE-RXN
+property_value: skos:exactMatch RHEA:34691
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -142403,6 +148429,9 @@
xref: RHEA:23056
xref: UM-BBD_reactionID:r0668
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.69
+property_value: skos:exactMatch RHEA:23056
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018822
@@ -142421,6 +148450,9 @@
xref: MetaCyc:NITRILE-HYDRATASE-RXN
xref: RHEA:12673
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.84
+property_value: skos:exactMatch RHEA:12673
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018823
@@ -142439,20 +148471,28 @@
xref: RHEA:21856
xref: UM-BBD_reactionID:r0203
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.100
+property_value: skos:exactMatch RHEA:21856
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018824
name: (hydroxyamino)benzene mutase activity
namespace: molecular_function
-def: "Catalysis of the reaction: (hydroxyamino)benzene = 2-aminophenol." [EC:5.4.4.1, UM-BBD_reactionID:r0304]
+def: "Catalysis of the reaction: N-phenylhydroxylamine = 2-aminophenol." [RHEA:19245]
synonym: "(hydroxyamino)benzene hydroxymutase activity" RELATED [EC:5.4.4.1]
synonym: "HAB mutase activity" RELATED [EC:5.4.4.1]
synonym: "hydroxylaminobenzene hydroxymutase activity" RELATED [EC:5.4.4.1]
synonym: "hydroxylaminobenzene mutase activity" RELATED [EC:5.4.4.1]
+xref: EC:5.4.4.1
xref: MetaCyc:5.4.4.1-RXN
xref: RHEA:19245
xref: UM-BBD_reactionID:r0304
is_a: GO:0050486 ! intramolecular hydroxytransferase activity
+property_value: skos:exactMatch EC:5.4.4.1
+property_value: skos:exactMatch MetaCyc:5.4.4.1-RXN
+property_value: skos:exactMatch RHEA:19245
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0018825
@@ -142480,6 +148520,9 @@
xref: RHEA:23800
xref: UM-BBD_reactionID:r0432
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.11
+property_value: skos:exactMatch RHEA:23800
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018827
@@ -142554,6 +148597,9 @@
xref: RHEA:19217
xref: UM-BBD_reactionID:r0439
is_a: GO:0016848 ! carbon-halide lyase activity
+property_value: skos:exactMatch EC:4.5.1.1
+property_value: skos:exactMatch RHEA:19217
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018834
@@ -142568,6 +148614,9 @@
xref: RHEA:15397
xref: UM-BBD_reactionID:r0188
is_a: GO:0016848 ! carbon-halide lyase activity
+property_value: skos:exactMatch EC:4.5.1.3
+property_value: skos:exactMatch RHEA:15397
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018835
@@ -142577,6 +148626,8 @@
def: "Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate)." [PMID:3804975]
xref: EC:4.7.1.-
is_a: GO:0016829 ! lyase activity
+property_value: skos:exactMatch EC:4.7.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018836
@@ -142591,6 +148642,9 @@
xref: MetaCyc:ALKYLMERCURY-LYASE-RXN
xref: RHEA:18777
is_a: GO:0016829 ! lyase activity
+property_value: skos:exactMatch EC:4.99.1.2
+property_value: skos:exactMatch RHEA:18777
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018837
@@ -142611,6 +148665,9 @@
xref: RHEA:13945
xref: UM-BBD_reactionID:r0091
is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives
+property_value: skos:exactMatch EC:5.1.2.2
+property_value: skos:exactMatch RHEA:13945
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018839
@@ -142641,6 +148698,9 @@
xref: RHEA:27401
xref: UM-BBD_reactionID:r0337
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:exactMatch EC:5.99.1.4
+property_value: skos:exactMatch RHEA:27401
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018846
@@ -142656,6 +148716,9 @@
xref: RHEA:21604
xref: UM-BBD_reactionID:r0034
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:exactMatch EC:5.3.99.7
+property_value: skos:exactMatch RHEA:21604
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018847
@@ -142690,7 +148753,10 @@
xref: MetaCyc:MUCONATE-CYCLOISOMERASE-RXN
xref: RHEA:30031
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.1
+property_value: skos:exactMatch RHEA:30031
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21794" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018850
@@ -142702,6 +148768,9 @@
xref: EC:5.5.1.7
xref: RHEA:11032
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.7
+property_value: skos:exactMatch RHEA:11032
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018851
@@ -142716,6 +148785,9 @@
xref: RHEA:16693
xref: UM-BBD_reactionID:r0743
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.10
+property_value: skos:exactMatch RHEA:16693
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018852
@@ -142728,6 +148800,9 @@
xref: RHEA:17437
xref: UM-BBD_reactionID:r0277
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.11
+property_value: skos:exactMatch RHEA:17437
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018853
@@ -142757,6 +148832,9 @@
xref: UM-BBD_reactionID:r0429
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.38
+property_value: skos:exactMatch RHEA:33419
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018856
@@ -142794,6 +148872,9 @@
xref: UM-BBD_reactionID:r0189
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.25
+property_value: skos:exactMatch RHEA:10132
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018859
@@ -142812,6 +148893,9 @@
xref: UM-BBD_reactionID:r0156
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.27
+property_value: skos:exactMatch RHEA:23116
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018860
@@ -142831,6 +148915,9 @@
xref: UM-BBD_reactionID:r0341
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.32
+property_value: skos:exactMatch RHEA:10828
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018861
@@ -142845,6 +148932,9 @@
xref: UM-BBD_reactionID:r0139
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.33
+property_value: skos:exactMatch RHEA:23220
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018862
@@ -142858,7 +148948,10 @@
xref: RHEA:74015
xref: UM-BBD_reactionID:r0157
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.123
+property_value: skos:exactMatch RHEA:74015
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28067" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0018863
@@ -143480,7 +149573,6 @@
synonym: "iprodione metabolism" EXACT []
xref: UM-BBD_pathwayID:ipd
is_a: GO:0042537 ! benzene-containing compound metabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0052803 ! imidazole-containing compound metabolic process
is_a: GO:0090345 ! organohalogen metabolic process
@@ -144343,8 +150435,21 @@
synonym: "juvenile hormone-III synthase activity" EXACT []
synonym: "S-adenosyl-methionine:farnesoic acid O-methyltransferase activity" EXACT []
xref: EC:2.1.1.325
+xref: KEGG_REACTION:R08147
+xref: KEGG_REACTION:R08151
+xref: MetaCyc:RXN-11587
+xref: MetaCyc:RXN-11771
+xref: RHEA:43700
+xref: RHEA:43720
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.325
+property_value: skos:narrowMatch KEGG_REACTION:R08147
+property_value: skos:narrowMatch KEGG_REACTION:R08151
+property_value: skos:narrowMatch MetaCyc:RXN-11587
+property_value: skos:narrowMatch MetaCyc:RXN-11771
+property_value: skos:narrowMatch RHEA:43700
+property_value: skos:narrowMatch RHEA:43720
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27388" xsd:anyURI
[Term]
@@ -144737,6 +150842,8 @@
synonym: "induction of apoptosis in host by virus" EXACT []
synonym: "positive regulation of apoptosis by virus" NARROW []
synonym: "positive regulation of apoptotic process by virus" EXACT []
+xref: VZ:910 "Activation of host caspases by virus"
+property_value: skos:narrowMatch VZ:910
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23652" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26877" xsd:anyURI
is_obsolete: true
@@ -145379,7 +151486,10 @@
xref: RHEA:11804
xref: UM-BBD_reactionID:r0394
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.29
+property_value: skos:exactMatch RHEA:11804
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019111
@@ -145452,7 +151562,11 @@
name: phenanthrene-epoxide hydrolase activity
namespace: molecular_function
def: "Catalysis of the reaction: a phenanthrene dioxide + H2O = a dihydrodiolphenanthrene." [GOC:mah, UM-BBD_reactionID:r0535, UM-BBD_reactionID:r0536]
+xref: UM-BBD_reactionID:r0535
+xref: UM-BBD_reactionID:r0536
is_a: GO:0004301 ! epoxide hydrolase activity
+property_value: skos:narrowMatch UM-BBD_reactionID:r0535
+property_value: skos:narrowMatch UM-BBD_reactionID:r0536
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27074" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
@@ -145461,16 +151575,23 @@
name: phenanthrene-9,10-epoxide hydrolase activity
namespace: molecular_function
def: "Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9,10-dihydrodiolphenanthrene." [GOC:mah, UM-BBD_reactionID:r0496, UM-BBD_reactionID:r0560]
+xref: UM-BBD_reactionID:r0496
+xref: UM-BBD_reactionID:r0560
is_a: GO:0019118 ! phenanthrene-epoxide hydrolase activity
+property_value: skos:narrowMatch UM-BBD_reactionID:r0496
+property_value: skos:narrowMatch UM-BBD_reactionID:r0560
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
[Term]
id: GO:0019120
-name: hydrolase activity, acting on acid halide bonds, in C-halide compounds
+name: hydrolase activity, acting on halide bonds, in C-halide compounds
namespace: molecular_function
-def: "Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage." [EC:3.8.1.-]
+def: "Catalysis of the hydrolysis of any halide bond in substances containing halogen atoms in organic linkage." [EC:3.8.1.-]
xref: EC:3.8.1.-
-is_a: GO:0016824 ! hydrolase activity, acting on acid halide bonds
+is_a: GO:0016824 ! hydrolase activity, acting on halide bonds
+property_value: skos:exactMatch EC:3.8.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30700" xsd:anyURI
[Term]
id: GO:0019121
@@ -145483,15 +151604,13 @@
[Term]
id: GO:0019122
-name: peptidyl-D-alanine racemization
+name: obsolete peptidyl-D-alanine racemization
namespace: biological_process
-def: "The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine." [RESID:AA0191]
-comment: See also the biological process terms 'peptidyl-D-alanine racemization, direct ; GO:0019916' and 'peptidyl-D-alanine racemization via peptidyl-L-serine ; GO:0019917'.
-subset: gocheck_do_not_annotate
+def: "OBSOLETE. The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine." [GOC:ew]
+comment: The reason for obsoletion is that this term represents a molecular function.
synonym: "alanine racemization" BROAD []
-xref: RESID:AA0191
-is_a: GO:0018085 ! peptidyl-L-amino acid racemization
-is_a: GO:0018194 ! peptidyl-alanine modification
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31180" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0019123
@@ -145597,6 +151716,9 @@
xref: MetaCyc:RXN1F-357
xref: RHEA:17769
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.15.7
+property_value: skos:exactMatch RHEA:17769
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019134
@@ -145610,6 +151732,9 @@
xref: MetaCyc:2.3.1.157-RXN
xref: RHEA:13725
is_a: GO:0008080 ! N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.157
+property_value: skos:exactMatch RHEA:13725
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019135
@@ -145627,6 +151752,9 @@
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:1.14.99.29
+property_value: skos:exactMatch RHEA:14101
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019136
@@ -145647,7 +151775,10 @@
xref: RHEA:12140
is_a: GO:0019205 ! nucleobase-containing compound kinase activity
relationship: part_of GO:0009157 ! deoxyribonucleoside monophosphate biosynthetic process
+property_value: skos:exactMatch EC:2.7.1.145
+property_value: skos:exactMatch RHEA:12140
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27917" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019137
@@ -145661,6 +151792,7 @@
xref: EC:3.2.1.147
xref: MetaCyc:RXN-9946
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.147
[Term]
id: GO:0019139
@@ -145677,6 +151809,10 @@
xref: MetaCyc:1.5.99.12-RXN
xref: RHEA:13625
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.99.12
+property_value: skos:exactMatch MetaCyc:1.5.99.12-RXN
+property_value: skos:exactMatch RHEA:13625
+property_value: skos:relatedMatch MetaCyc:PWY-2841
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -145695,6 +151831,9 @@
xref: RHEA:21804
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.64
+property_value: skos:exactMatch RHEA:21804
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019141
@@ -145708,7 +151847,10 @@
synonym: "ketopantoyl lactone reductase activity" BROAD [EC:1.1.1.214]
xref: EC:1.1.1.214
is_a: GO:0036441 ! 2-dehydropantolactone reductase activity
+property_value: skos:broadMatch MetaCyc:1.1.1.168-RXN
+property_value: skos:exactMatch EC:1.1.1.214
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019142
@@ -145726,6 +151868,9 @@
xref: MetaCyc:HYDGLUTSYN-RXN
xref: RHEA:19185
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.11
+property_value: skos:exactMatch RHEA:19185
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019143
@@ -145738,20 +151883,25 @@
xref: MetaCyc:KDO-8PPHOSPHAT-RXN
xref: RHEA:11500
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.45
+property_value: skos:exactMatch RHEA:11500
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019144
-name: ADP-sugar diphosphatase activity
+name: ADP-sugar pyrophosphatase activity
namespace: molecular_function
-def: "Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate." [EC:3.6.1.21]
+def: "Catalysis of the reaction: ADP-sugar + H2O = AMP + alpha-D-aldose 1-phosphate." [EC:3.6.1.21]
synonym: "adenosine diphosphosugar pyrophosphatase activity" RELATED [EC:3.6.1.21]
-synonym: "ADP-sugar pyrophosphatase activity" RELATED [EC:3.6.1.21]
+synonym: "ADP-sugar diphosphatase activity" EXACT []
synonym: "ADP-sugar sugarphosphohydrolase activity" RELATED [EC:3.6.1.21]
synonym: "ADPsugar pyrophosphatase activity" RELATED [EC:3.6.1.21]
synonym: "nucleoside diphosphate-sugar hydrolase activity" BROAD [GOC:vw]
xref: EC:3.6.1.21
xref: MetaCyc:ADPSUGPPHOSPHAT-RXN
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.21
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019145
@@ -145767,6 +151917,9 @@
xref: MetaCyc:AMINOBUTDEHYDROG-RXN
xref: RHEA:19105
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.19
+property_value: skos:exactMatch RHEA:19105
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019146
@@ -145782,6 +151935,9 @@
xref: MetaCyc:DARAB5PISOM-RXN
xref: RHEA:23104
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.13
+property_value: skos:exactMatch RHEA:23104
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019147
@@ -145800,6 +151956,9 @@
xref: MetaCyc:AMINOPROPDEHYDROG-RXN
xref: RHEA:16517
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.75
+property_value: skos:exactMatch RHEA:16517
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019148
@@ -145813,6 +151972,9 @@
xref: MetaCyc:DCYSDESULF-RXN
xref: RHEA:11268
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.15
+property_value: skos:exactMatch RHEA:11268
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019149
@@ -145826,6 +151988,9 @@
xref: MetaCyc:3-CHLORO-D-ALANINE-DEHYDROCHLORINASE-RXN
xref: RHEA:18873
is_a: GO:0016848 ! carbon-halide lyase activity
+property_value: skos:exactMatch EC:4.5.1.2
+property_value: skos:exactMatch RHEA:18873
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019150
@@ -145839,6 +152004,9 @@
xref: RHEA:17601
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.47
+property_value: skos:exactMatch RHEA:17601
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019151
@@ -145854,6 +152022,9 @@
xref: MetaCyc:GALACTODEHYDROG-RXN
xref: RHEA:21296
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.48
+property_value: skos:exactMatch RHEA:21296
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019152
@@ -145882,7 +152053,10 @@
xref: RHEA:21064
is_a: GO:0015035 ! protein-disulfide reductase activity
is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
+property_value: skos:exactMatch EC:1.8.4.2
+property_value: skos:exactMatch RHEA:21064
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21148" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019154
@@ -145898,6 +152072,9 @@
xref: MetaCyc:GLYCOLATEDEHYDRO-RXN
xref: RHEA:21264
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.14
+property_value: skos:exactMatch RHEA:21264
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019155
@@ -145909,6 +152086,8 @@
xref: EC:1.1.1.111
xref: MetaCyc:IMILACTDEHYDROG-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.111
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019156
@@ -145919,7 +152098,13 @@
synonym: "glycogen alpha-1,6-glucanohydrolase activity" RELATED [EC:3.2.1.68]
xref: EC:3.2.1.68
xref: MetaCyc:3.2.1.68-RXN
+xref: MetaCyc:RXN-12280
+xref: MetaCyc:RXN-14380
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.68
+property_value: skos:exactMatch MetaCyc:3.2.1.68-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-12280
+property_value: skos:narrowMatch MetaCyc:RXN-14380
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -145944,10 +152129,12 @@
synonym: "mannokinase (phosphorylating)" RELATED [EC:2.7.1.7]
xref: EC:2.7.1.7
xref: MetaCyc:MANNKIN-RXN
-xref: Reactome:R-HSA-8931653 "POMK 6-phosphorylates mannose in GalNAc-GlcNAc-Man-DAG1"
xref: Reactome:R-HSA-9909159 "HK1 phosphorylates Mannose to Man6P"
xref: RHEA:11028
is_a: GO:0004396 ! hexokinase activity
+property_value: skos:exactMatch EC:2.7.1.7
+property_value: skos:exactMatch RHEA:11028
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019159
@@ -145963,6 +152150,9 @@
xref: MetaCyc:NMNAMIDOHYDRO-RXN
xref: RHEA:12400
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.42
+property_value: skos:exactMatch RHEA:12400
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019160
@@ -145980,6 +152170,9 @@
xref: MetaCyc:NMNNUCLEOSID-RXN
xref: RHEA:23140
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.2.14
+property_value: skos:exactMatch RHEA:23140
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019161
@@ -145995,6 +152188,9 @@
xref: MetaCyc:DIAMTRANSAM-RXN
xref: RHEA:18217
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.29
+property_value: skos:exactMatch RHEA:18217
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019162
@@ -146009,6 +152205,9 @@
xref: MetaCyc:PYROXALTRANSAM-RXN
xref: RHEA:10844
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.31
+property_value: skos:exactMatch RHEA:10844
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019163
@@ -146024,6 +152223,9 @@
xref: MetaCyc:PYRDAMPTRANS-RXN
xref: RHEA:15877
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.54
+property_value: skos:exactMatch RHEA:15877
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019164
@@ -146044,6 +152246,9 @@
xref: RHEA:12765
is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor
relationship: part_of GO:0006086 ! pyruvate decarboxylation to acetyl-CoA
+property_value: skos:exactMatch EC:1.2.7.1
+property_value: skos:exactMatch RHEA:12765
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019165
@@ -146061,6 +152266,9 @@
xref: RHEA:12012
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.89
+property_value: skos:exactMatch RHEA:12012
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019166
@@ -146077,6 +152285,9 @@
xref: Reactome:R-HSA-8952873 "MECR dimer reduces tdec2-CoA to DEC-CoA"
xref: RHEA:33763
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.38
+property_value: skos:exactMatch RHEA:33763
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019168
@@ -146088,6 +152299,8 @@
xref: MetaCyc:RXN-18459
xref: RHEA:55892
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.240
+property_value: skos:exactMatch RHEA:55892
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
[Term]
@@ -146103,7 +152316,10 @@
xref: MetaCyc:D-LACTALDEHYDE-DEHYDROGENASE-RXN
xref: RHEA:24528
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.78
+property_value: skos:exactMatch RHEA:24528
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019171
@@ -146118,6 +152334,9 @@
xref: MetaCyc:3-HYDROXYDECANOYL-ACP-DEHYDR-RXN
xref: RHEA:13097
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.59
+property_value: skos:exactMatch RHEA:13097
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019172
@@ -146134,6 +152353,9 @@
is_a: GO:0016836 ! hydro-lyase activity
relationship: part_of GO:0019249 ! lactate biosynthetic process
relationship: part_of GO:0061727 ! methylglyoxal catabolic process to lactate
+property_value: skos:exactMatch EC:4.2.1.130
+property_value: skos:exactMatch RHEA:27754
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019174
@@ -146154,6 +152376,8 @@
xref: MetaCyc:DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN
xref: RHEA:25306
is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
+property_value: skos:exactMatch RHEA:25306
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019177
@@ -146164,7 +152388,10 @@
xref: MetaCyc:H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN
xref: RHEA:25302
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.67
+property_value: skos:exactMatch RHEA:25302
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019178
@@ -146174,6 +152401,8 @@
xref: MetaCyc:RXN-5822
xref: RHEA:28050
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.108
+property_value: skos:exactMatch RHEA:28050
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -146193,6 +152422,9 @@
xref: MetaCyc:2.6.1.33-RXN
xref: RHEA:19085
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.33
+property_value: skos:exactMatch RHEA:19085
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019180
@@ -146209,6 +152441,9 @@
xref: MetaCyc:RFFTRANS-RXN
xref: RHEA:10368
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.59
+property_value: skos:exactMatch RHEA:10368
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019181
@@ -146333,6 +152568,7 @@
name: carbohydrate kinase activity
namespace: molecular_function
def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule." [GOC:jl]
+xref: Reactome:R-HSA-8931653 "POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1"
is_a: GO:0016301 ! kinase activity
relationship: part_of GO:0046835 ! carbohydrate phosphorylation
@@ -146419,7 +152655,6 @@
name: kinase inhibitor activity
namespace: molecular_function
def: "Binds to and stops, prevents or reduces the activity of a kinase." [GOC:mah]
-xref: Reactome:R-HSA-170824 "glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex"
is_a: GO:0004857 ! enzyme inhibitor activity
is_a: GO:0019207 ! kinase regulator activity
relationship: negatively_regulates GO:0016301 ! kinase activity
@@ -146429,11 +152664,6 @@
name: phosphatase activator activity
namespace: molecular_function
def: "Binds to and increases the activity of a phosphatase." [GOC:ai]
-xref: Reactome:R-HSA-6809238 "MTMR7 binds MTMR9"
-xref: Reactome:R-HSA-6809254 "MTMR8 binds MTMR9"
-xref: Reactome:R-HSA-6809309 "MTMR6 binds MTMR9"
-xref: Reactome:R-HSA-6809680 "MTMR12 binds MTM1"
-xref: Reactome:R-HSA-6809793 "MTMR2 binds SBF2"
is_a: GO:0008047 ! enzyme activator activity
is_a: GO:0019208 ! phosphatase regulator activity
relationship: positively_regulates GO:0016791 ! phosphatase activity
@@ -146455,6 +152685,9 @@
subset: goslim_pir
xref: Reactome:R-HSA-5689000 "AADAC deacetylates PHEN"
is_a: GO:0160215 ! deacylase activity
+property_value: skos:broadMatch EC:2.3.1.-
+property_value: skos:broadMatch EC:3.1.1.-
+property_value: skos:broadMatch EC:3.5.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28920" xsd:anyURI
[Term]
@@ -146686,6 +152919,7 @@
def: "Catalysis of the removal of an amino group from a substrate, producing a substituted or nonsubstituted ammonia (NH3/NH2R)." [GOC:jl]
subset: goslim_pir
xref: Reactome:R-HSA-74241 "ADA catalyzes the deamination of (deoxy)adenosine"
+xref: Reactome:R-HSA-9014641 "HRSP12 deaminates 2AA to 2OBUTA"
xref: Reactome:R-HSA-9734745 "Defective ADA does not deaminate (deoxy)adenosine"
xref: Reactome:R-HSA-9754964 "ADA deamidates RBV"
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
@@ -146991,25 +153225,29 @@
[Term]
id: GO:0019264
-name: glycine biosynthetic process from serine
+name: glycine biosynthetic process from L-serine
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine." [GOC:go_curators]
+def: "The chemical reactions and pathways resulting in the formation of glycine from L-serine." [MetaCyc:GLYSYN-PWY]
synonym: "glycine anabolism from serine" EXACT []
synonym: "glycine formation from serine" EXACT []
synonym: "glycine synthesis from serine" EXACT []
xref: MetaCyc:GLYSYN-PWY
is_a: GO:0006545 ! glycine biosynthetic process
is_a: GO:0006563 ! L-serine metabolic process
+property_value: skos:exactMatch MetaCyc:GLYSYN-PWY
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30758" xsd:anyURI
[Term]
id: GO:0019265
name: glycine biosynthetic process, by transamination of glyoxylate
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of glycine by the transamination of glyoxylate." [GOC:go_curators]
+def: "The chemical reactions and pathways resulting in the formation of glycine by the transamination of glyoxylate." [GOC:go_curators, MetaCyc:GLYSYN-ALA-PWY]
synonym: "glycine anabolism, by transamination of glyoxylate" EXACT []
synonym: "glycine formation, by transamination of glyoxylate" EXACT []
synonym: "glycine synthesis, by transamination of glyoxylate" EXACT []
+xref: MetaCyc:GLYSYN-ALA-PWY
is_a: GO:0006545 ! glycine biosynthetic process
+property_value: skos:exactMatch MetaCyc:GLYSYN-ALA-PWY
[Term]
id: GO:0019266
@@ -147021,7 +153259,6 @@
synonym: "asparagine synthesis from oxaloacetate" EXACT []
xref: MetaCyc:ASPARAGINE-BIOSYNTHESIS
is_a: GO:0006107 ! oxaloacetate metabolic process
-is_a: GO:0043605 ! amide catabolic process
is_a: GO:0043649 ! dicarboxylic acid catabolic process
is_a: GO:0070981 ! L-asparagine biosynthetic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29444" xsd:anyURI
@@ -147091,24 +153328,27 @@
id: GO:0019272
name: L-alanine biosynthetic process from pyruvate
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate." [GOC:go_curators]
+def: "The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate." [GOC:go_curators, MetaCyc:ALANINE-SYN2-PWY]
synonym: "L-alanine anabolism from pyruvate" EXACT []
synonym: "L-alanine formation from pyruvate" EXACT []
synonym: "L-alanine synthesis from pyruvate" EXACT []
+xref: MetaCyc:ALANINE-SYN2-PWY
is_a: GO:0006090 ! pyruvate metabolic process
is_a: GO:0042852 ! L-alanine biosynthetic process
+property_value: skos:exactMatch MetaCyc:ALANINE-SYN2-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
id: GO:0019273
-name: L-alanine biosynthetic process via ornithine
+name: obsolete L-alanine biosynthetic process via ornithine
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine." [GOC:go_curators]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine." [GOC:go_curators]
+comment: The reason for obsoletion is that there is no evidence that this process exists in vivo.
synonym: "L-alanine anabolism via ornithine" EXACT []
synonym: "L-alanine formation via ornithine" EXACT []
synonym: "L-alanine synthesis via ornithine" EXACT []
-is_a: GO:0006591 ! ornithine metabolic process
-is_a: GO:0042852 ! L-alanine biosynthetic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31091" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0019276
@@ -147128,9 +153368,13 @@
synonym: "UDP-N-acetylgalactosamine biosynthesis" EXACT []
synonym: "UDP-N-acetylgalactosamine formation" EXACT []
synonym: "UDP-N-acetylgalactosamine synthesis" EXACT []
+xref: MetaCyc:PWY-5514
+xref: MetaCyc:PWY-8013
is_a: GO:0009226 ! nucleotide-sugar biosynthetic process
is_a: GO:0019276 ! UDP-N-acetylgalactosamine metabolic process
is_a: GO:0046349 ! amino sugar biosynthetic process
+property_value: skos:narrowMatch MetaCyc:PWY-5514
+property_value: skos:narrowMatch MetaCyc:PWY-8013
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -147177,7 +153421,7 @@
id: GO:0019281
name: L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine." [GOC:go_curators]
+def: "The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine." [GOC:go_curators, MetaCyc:MET-SAM-PWY]
synonym: "L-methionine anabolism from homoserine via O-succinyl-L-homoserine and cystathionine" EXACT [GOC:mah]
synonym: "L-methionine formation from homoserine via O-succinyl-L-homoserine and cystathionine" EXACT [GOC:mah]
synonym: "L-methionine synthesis from homoserine via O-succinyl-L-homoserine and cystathionine" EXACT [GOC:mah]
@@ -147223,8 +153467,14 @@
synonym: "glycine betaine synthesis from choline" EXACT []
synonym: "N-trimethylglycine biosynthesis from choline" EXACT []
synonym: "N-trimethylglycine biosynthetic process from choline" EXACT []
+xref: MetaCyc:BETSYN-PWY
+xref: MetaCyc:PWY-3722
+xref: MetaCyc:PWY1F-353
is_a: GO:0019695 ! choline metabolic process
is_a: GO:0031456 ! glycine betaine biosynthetic process
+property_value: skos:narrowMatch MetaCyc:BETSYN-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-3722
+property_value: skos:narrowMatch MetaCyc:PWY1F-353
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -147293,7 +153543,6 @@
synonym: "rhizobactin 1021 formation" EXACT []
synonym: "rhizobactin 1021 synthesis" EXACT []
xref: MetaCyc:PWY-761
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0046394 ! carboxylic acid biosynthetic process
is_a: GO:1902645 ! tertiary alcohol biosynthetic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22894" xsd:anyURI
@@ -147919,38 +154168,44 @@
[Term]
id: GO:0019343
-name: cysteine biosynthetic process via cystathionine
+name: L-cysteine biosynthetic process via L-cystathionine
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine." [GOC:go_curators]
+def: "The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine." [GOC:go_curators, MetaCyc:HOMOCYSDEGR-PWY]
synonym: "cysteine anabolism via cystathionine" EXACT []
synonym: "cysteine formation via cystathionine" EXACT []
synonym: "cysteine synthesis via cystathionine" EXACT []
-is_a: GO:0019344 ! cysteine biosynthetic process
+xref: MetaCyc:HOMOCYSDEGR-PWY
+is_a: GO:0019344 ! L-cysteine biosynthetic process
+property_value: skos:exactMatch MetaCyc:HOMOCYSDEGR-PWY
[Term]
id: GO:0019344
-name: cysteine biosynthetic process
+name: L-cysteine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid." [GOC:go_curators]
+def: "The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid." [GOC:go_curators, MetaCyc:CYSTEINE-SYN]
synonym: "cysteine anabolism" EXACT []
synonym: "cysteine biosynthesis" EXACT []
synonym: "cysteine formation" EXACT []
synonym: "cysteine synthesis" EXACT []
+xref: MetaCyc:CYSTEINE-SYN
is_a: GO:0000097 ! sulfur amino acid biosynthetic process
is_a: GO:0006534 ! cysteine metabolic process
is_a: GO:0009070 ! serine family amino acid biosynthetic process
+property_value: skos:exactMatch MetaCyc:CYSTEINE-SYN
[Term]
id: GO:0019345
-name: cysteine biosynthetic process via S-sulfo-L-cysteine
+name: L-cysteine biosynthetic process via S-sulfo-L-cysteine
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine." [GOC:go_curators]
+def: "The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine." [GOC:go_curators, MetaCyc:PWY-7289]
synonym: "cysteine anabolism via S-sulfo-L-cysteine" EXACT []
synonym: "cysteine biosynthesis via S-sulpho-L-cysteine" EXACT []
synonym: "cysteine biosynthetic process via S-sulpho-L-cysteine" EXACT []
synonym: "cysteine formation via S-sulfo-L-cysteine" EXACT []
synonym: "cysteine synthesis via S-sulfo-L-cysteine" EXACT []
-is_a: GO:0019344 ! cysteine biosynthetic process
+xref: MetaCyc:PWY-7289
+is_a: GO:0019344 ! L-cysteine biosynthetic process
+property_value: skos:exactMatch MetaCyc:PWY-7289
[Term]
id: GO:0019346
@@ -148073,16 +154328,16 @@
[Term]
id: GO:0019356
-name: nicotinate nucleotide biosynthetic process from tryptophan
+name: obsolete nicotinate nucleotide biosynthetic process from tryptophan
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan." [GOC:go_curators]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan." [GOC:go_curators]
+comment: The reason for obsoletion is that this term is essentially equivalent to 'de novo' NAD+ biosynthetic process from L-tryptophan.
synonym: "nicotinate nucleotide anabolism from tryptophan" EXACT []
synonym: "nicotinate nucleotide formation from tryptophan" EXACT []
synonym: "nicotinate nucleotide synthesis from tryptophan" EXACT []
-is_a: GO:0009072 ! aromatic amino acid metabolic process
-is_a: GO:0019357 ! nicotinate nucleotide biosynthetic process
-is_a: GO:0042430 ! indole-containing compound metabolic process
-is_a: GO:1901605 ! alpha-amino acid metabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31022" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0034354
[Term]
id: GO:0019357
@@ -148102,8 +154357,10 @@
def: "The generation of nicotinate nucleotide without de novo synthesis." [GOC:go_curators]
synonym: "nicotinate nucleotide biosynthesis, salvage pathway" EXACT []
synonym: "nicotinate nucleotide biosynthetic process, salvage pathway" EXACT []
+xref: MetaCyc:PWY3O-224
is_a: GO:0019357 ! nicotinate nucleotide biosynthetic process
is_a: GO:0019365 ! pyridine nucleotide salvage
+property_value: skos:narrowMatch MetaCyc:PWY3O-224
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -148296,7 +154553,7 @@
synonym: "glycolipid catabolism" EXACT []
synonym: "glycolipid degradation" EXACT []
is_a: GO:0006664 ! glycolipid metabolic process
-is_a: GO:0046466 ! membrane lipid catabolic process
+is_a: GO:0016042 ! lipid catabolic process
is_a: GO:1901136 ! carbohydrate derivative catabolic process
[Term]
@@ -148323,6 +154580,7 @@
is_a: GO:0042178 ! xenobiotic catabolic process
is_a: GO:0042537 ! benzene-containing compound metabolic process
is_a: GO:0072329 ! monocarboxylic acid catabolic process
+property_value: skos:broadMatch MetaCyc:HCAMHPDEG-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
[Term]
@@ -148858,7 +155116,7 @@
synonym: "allantoin synthesis" EXACT []
xref: MetaCyc:URSIN-PWY
is_a: GO:0000255 ! allantoin metabolic process
-is_a: GO:0043604 ! amide biosynthetic process
+is_a: GO:0009058 ! biosynthetic process
[Term]
id: GO:0019429
@@ -148897,9 +155155,17 @@
synonym: "acetyl-CoA anabolism from ethanol" EXACT []
synonym: "acetyl-CoA formation from ethanol" EXACT []
synonym: "acetyl-CoA synthesis from ethanol" EXACT []
+xref: MetaCyc:ETOH-ACETYLCOA-ANA-PWY
+xref: MetaCyc:PWY66-161
+xref: MetaCyc:PWY66-162
+xref: MetaCyc:PWY66-21
is_a: GO:0006067 ! ethanol metabolic process
is_a: GO:0006085 ! acetyl-CoA biosynthetic process
is_a: GO:0006091 ! generation of precursor metabolites and energy
+property_value: skos:narrowMatch MetaCyc:ETOH-ACETYLCOA-ANA-PWY
+property_value: skos:narrowMatch MetaCyc:PWY66-161
+property_value: skos:narrowMatch MetaCyc:PWY66-162
+property_value: skos:narrowMatch MetaCyc:PWY66-21
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27260" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -148998,21 +155264,26 @@
synonym: "tryptophan catabolic process to indoleacetic acid" EXACT []
synonym: "tryptophan catabolism to indoleacetic acid" EXACT []
synonym: "tryptophan degradation to indole-3-acetate" EXACT []
-xref: MetaCyc:TRPIAACAT-PWY
is_a: GO:0006569 ! L-tryptophan catabolic process
is_a: GO:0032787 ! monocarboxylic acid metabolic process
+property_value: skos:relatedMatch MetaCyc:PWY-3181
+property_value: skos:relatedMatch MetaCyc:PWY-6307
+property_value: skos:relatedMatch MetaCyc:TRPIAACAT-PWY
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31028" xsd:anyURI
[Term]
id: GO:0019441
-name: L-tryptophan catabolic process to kynurenine
+name: L-tryptophan catabolic process to L-kynurenine
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of L-tryptophan into other compounds, including kynurenine." [GOC:go_curators]
+def: "The chemical reactions and pathways resulting in the breakdown of L-tryptophan into other compounds, including L-kynurenine." [GOC:go_curators, MetaCyc:PWY-6309, PMID:31704347]
synonym: "tryptophan breakdown to kynurenine" EXACT []
synonym: "tryptophan catabolic process to kynurenine" EXACT []
synonym: "tryptophan degradation to kynurenine" EXACT []
-xref: MetaCyc:TRPKYNCAT-PWY
+xref: MetaCyc:PWY-6309
is_a: GO:0006569 ! L-tryptophan catabolic process
-is_a: GO:0070189 ! kynurenine metabolic process
+is_a: GO:0097052 ! L-kynurenine metabolic process
+property_value: skos:exactMatch MetaCyc:PWY-6309
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31028" xsd:anyURI
[Term]
id: GO:0019442
@@ -149022,10 +155293,12 @@
synonym: "tryptophan breakdown to acetyl-CoA" EXACT []
synonym: "tryptophan catabolic process to acetyl-CoA" EXACT []
synonym: "tryptophan degradation to acetyl-CoA" EXACT []
-xref: MetaCyc:TRYPTOPHAN-DEGRADATION-1
is_a: GO:0006084 ! acetyl-CoA metabolic process
is_a: GO:0006569 ! L-tryptophan catabolic process
-is_a: GO:0043605 ! amide catabolic process
+property_value: skos:relatedMatch MetaCyc:PWY-5655
+property_value: skos:relatedMatch MetaCyc:PWY-6505
+property_value: skos:relatedMatch MetaCyc:TRYPTOPHAN-DEGRADATION-1
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31028" xsd:anyURI
[Term]
id: GO:0019443
@@ -149063,7 +155336,6 @@
xref: MetaCyc:TYRFUMCAT-PWY
is_a: GO:0006106 ! fumarate metabolic process
is_a: GO:0006572 ! L-tyrosine catabolic process
-is_a: GO:0043650 ! dicarboxylic acid biosynthetic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
[Term]
@@ -149084,7 +155356,8 @@
synonym: "D-cysteine breakdown" EXACT []
synonym: "D-cysteine catabolism" EXACT []
synonym: "D-cysteine degradation" EXACT []
-is_a: GO:0009093 ! cysteine catabolic process
+is_a: GO:0000098 ! sulfur amino acid catabolic process
+is_a: GO:0006534 ! cysteine metabolic process
is_a: GO:0019478 ! D-amino acid catabolic process
[Term]
@@ -149095,7 +155368,7 @@
synonym: "L-cysteine breakdown" EXACT []
synonym: "L-cysteine catabolism" EXACT []
synonym: "L-cysteine degradation" EXACT []
-is_a: GO:0009093 ! cysteine catabolic process
+is_a: GO:0000098 ! sulfur amino acid catabolic process
is_a: GO:0046439 ! L-cysteine metabolic process
is_a: GO:0170035 ! L-amino acid catabolic process
is_a: GO:0170040 ! proteinogenic amino acid catabolic process
@@ -149191,7 +155464,6 @@
xref: MetaCyc:METHIONINE-DEG1-PWY
is_a: GO:0006104 ! succinyl-CoA metabolic process
is_a: GO:0009087 ! L-methionine catabolic process
-is_a: GO:0043605 ! amide catabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
[Term]
@@ -149284,7 +155556,7 @@
synonym: "ornithine breakdown via proline" EXACT []
synonym: "ornithine degradation via proline" EXACT []
xref: MetaCyc:ORN-AMINOPENTANOATE-CAT-PWY
-is_a: GO:0006560 ! proline metabolic process
+is_a: GO:0006560 ! L-proline metabolic process
is_a: GO:0006593 ! L-ornithine catabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
@@ -149370,6 +155642,7 @@
synonym: "L-lysine degradation to glutarate, by acetylation" EXACT []
xref: MetaCyc:LYSDEGII-PWY
is_a: GO:0019477 ! L-lysine catabolic process
+is_a: GO:0043648 ! dicarboxylic acid metabolic process
[Term]
id: GO:0019474
@@ -149378,24 +155651,28 @@
def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA." [GOC:go_curators]
synonym: "L-lysine breakdown to acetyl-CoA" EXACT []
synonym: "L-lysine degradation to acetyl-CoA" EXACT []
+xref: MetaCyc:PWY-5177
is_a: GO:0006084 ! acetyl-CoA metabolic process
is_a: GO:0019477 ! L-lysine catabolic process
-is_a: GO:0043605 ! amide catabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-5177
[Term]
id: GO:0019475
name: L-lysine fermentation
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetate." [PMID:21826218]
+def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into acetyl-CoA and butanoate. Acetyl-CoA can be further converted into acetate, releasing one ATP molecule." [MetaCyc:P163-PWY, PMID:17166837]
+synonym: "3-keto-5-aminohexanoate pathway" EXACT [MetaCyc:P163-PWY]
synonym: "L-lysine breakdown to acetate" EXACT []
-synonym: "L-lysine catabolic process to butyrate and acetate" EXACT []
+synonym: "L-lysine catabolic process to butyrate and acetate" EXACT [MetaCyc:P163-PWY]
synonym: "L-lysine degradation to acetate" EXACT []
-synonym: "lysine fermentation" EXACT []
+synonym: "L-lysine fermentation to acetic acid and butanoic acid" EXACT [MetaCyc:P163-PWY]
xref: MetaCyc:P163-PWY
is_a: GO:0006083 ! acetate metabolic process
is_a: GO:0019477 ! L-lysine catabolic process
-is_a: GO:0019665 ! anaerobic amino acid catabolic process
+is_a: GO:0019605 ! butyrate metabolic process
+is_a: GO:0019665 ! amino acid fermentation
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31218" xsd:anyURI
[Term]
id: GO:0019476
@@ -149405,7 +155682,7 @@
synonym: "D-lysine breakdown" EXACT []
synonym: "D-lysine catabolism" EXACT []
synonym: "D-lysine degradation" EXACT []
-is_a: GO:0006554 ! lysine catabolic process
+is_a: GO:0006553 ! lysine metabolic process
is_a: GO:0019478 ! D-amino acid catabolic process
[Term]
@@ -149416,7 +155693,7 @@
synonym: "L-lysine breakdown" EXACT []
synonym: "L-lysine catabolism" EXACT []
synonym: "L-lysine degradation" EXACT []
-is_a: GO:0006554 ! lysine catabolic process
+is_a: GO:0006553 ! lysine metabolic process
is_a: GO:0170035 ! L-amino acid catabolic process
is_a: GO:0170040 ! proteinogenic amino acid catabolic process
@@ -149574,12 +155851,13 @@
[Term]
id: GO:0019492
-name: proline salvage
+name: L-proline salvage
namespace: biological_process
-def: "Any process which produces the amino acid proline from derivatives of it, without de novo synthesis." [GOC:jl]
+def: "Any process which produces L-proline from derivatives of it, without de novo synthesis." [GOC:jl]
synonym: "proline cycling" EXACT []
is_a: GO:0043102 ! amino acid salvage
is_a: GO:0055129 ! L-proline biosynthetic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30816" xsd:anyURI
[Term]
id: GO:0019493
@@ -149590,7 +155868,7 @@
synonym: "arginine degradation to proline" EXACT []
xref: MetaCyc:ARG-PRO-PWY
is_a: GO:0006527 ! L-arginine catabolic process
-is_a: GO:0006560 ! proline metabolic process
+is_a: GO:0006560 ! L-proline metabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
[Term]
@@ -149622,7 +155900,11 @@
namespace: biological_process
def: "The chemical reactions and pathways involving hexachlorocyclohexane, a cyclohexane derivative with 6 chlorine atoms attached to the hexane ring. Hexachlorocyclohexane consists of a mixture of 8 different isomers and was used a commercial insecticide. It is persistent in the environment, causing serious soil pollution." [UM-BBD_pathwayID:ghch, UM-BBD_pathwayID:hch]
synonym: "hexachlorocyclohexane metabolism" EXACT []
+xref: UM-BBD_pathwayID:ghch
+xref: UM-BBD_pathwayID:hch
is_a: GO:0042197 ! halogenated hydrocarbon metabolic process
+property_value: skos:narrowMatch UM-BBD_pathwayID:ghch
+property_value: skos:narrowMatch UM-BBD_pathwayID:hch
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
[Term]
@@ -149881,8 +156163,9 @@
synonym: "threonine catabolic process to glycine" BROAD [GOC:bf]
xref: MetaCyc:THREONINE-DEG2-PWY
xref: Reactome:R-HSA-8849175 "Threonine catabolism"
-is_a: GO:0006545 ! glycine biosynthetic process
+is_a: GO:0006544 ! glycine metabolic process
is_a: GO:0006567 ! L-threonine catabolic process
+property_value: skos:exactMatch MetaCyc:THREONINE-DEG2-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30734" xsd:anyURI
[Term]
@@ -150058,7 +156341,6 @@
def: "The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae." [GOC:jl, PMID:11112537]
synonym: "vibriobactin metabolism" EXACT []
is_a: GO:0009237 ! siderophore metabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0019537
@@ -150073,8 +156355,8 @@
synonym: "vibriobactin biosynthetic process, peptide modification" NARROW []
synonym: "vibriobactin formation" EXACT []
synonym: "vibriobactin synthesis" EXACT []
+is_a: GO:0009058 ! biosynthetic process
is_a: GO:0019536 ! vibriobactin metabolic process
-is_a: GO:0043604 ! amide biosynthetic process
[Term]
id: GO:0019538
@@ -150166,8 +156448,12 @@
def: "The chemical reactions and pathways resulting in the breakdown of L-arginine into other compounds, including L-glutamate." [GOC:go_curators]
synonym: "arginine breakdown to glutamate" EXACT []
synonym: "arginine degradation to glutamate" EXACT []
+xref: MetaCyc:ARG-GLU-PWY
+xref: MetaCyc:ARGASEDEG-PWY
is_a: GO:0006527 ! L-arginine catabolic process
is_a: GO:0006536 ! glutamate metabolic process
+property_value: skos:narrowMatch MetaCyc:ARG-GLU-PWY
+property_value: skos:narrowMatch MetaCyc:ARGASEDEG-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
@@ -150178,8 +156464,16 @@
def: "The chemical reactions and pathways resulting in the breakdown of L-arginine into other compounds, including succinate." [GOC:go_curators]
synonym: "arginine breakdown to succinate" EXACT []
synonym: "arginine degradation to succinate" EXACT []
+xref: MetaCyc:ARGDEG-III-PWY
+xref: MetaCyc:ARGDEG-IV-PWY
+xref: MetaCyc:ARGDEG-V-PWY
+xref: MetaCyc:AST-PWY
is_a: GO:0006105 ! succinate metabolic process
is_a: GO:0006527 ! L-arginine catabolic process
+property_value: skos:narrowMatch MetaCyc:ARGDEG-III-PWY
+property_value: skos:narrowMatch MetaCyc:ARGDEG-IV-PWY
+property_value: skos:narrowMatch MetaCyc:ARGDEG-V-PWY
+property_value: skos:narrowMatch MetaCyc:AST-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
@@ -150207,15 +156501,15 @@
[Term]
id: GO:0019548
-name: arginine catabolic process to spermine
+name: obsolete arginine catabolic process to spermine
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine." [GOC:go_curators]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine." [GOC:go_curators]
+comment: The reason for obsoletion is that this term was added in error.
synonym: "arginine breakdown to spermine" EXACT []
synonym: "arginine degradation to spermine" EXACT []
-xref: MetaCyc:ARGSPECAT-PWY
-is_a: GO:0006525 ! arginine metabolic process
-is_a: GO:0008215 ! spermine metabolic process
-is_a: GO:1901606 ! alpha-amino acid catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31091" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0006597
[Term]
id: GO:0019549
@@ -150259,40 +156553,40 @@
[Term]
id: GO:0019552
-name: L-glutamate catabolic process via 2-hydroxyglutarate
+name: L-glutamate fermentation via 2-hydroxyglutarate
namespace: biological_process
-def: "The anaerobic chemical reactions and pathways resulting in the breakdown of L-glutamate, via the intermediate 2-hydroxyglutarate, yielding energy in the form of ATP." [MetaCyc:P162-PWY]
-synonym: "glutamate fermentation via 2-hydroxyglutarate" EXACT []
+def: "The anaerobic chemical reactions and pathways resulting in the breakdown of L-glutamate, via the intermediate 2-hydroxyglutarate, yielding acetyl-CoA and butanoate. Acetyl-CoA can be further converted into acetate, releasing one ATP molecule." [PMID:17166837]
+synonym: "L-glutamate catabolic process via 2-hydroxyglutarate" EXACT []
xref: MetaCyc:P162-PWY
-is_a: GO:0006083 ! acetate metabolic process
-is_a: GO:0019670 ! anaerobic L-glutamate catabolic process
-is_a: GO:0033508 ! L-glutamate catabolic process to butyrate
+is_a: GO:0006538 ! L-glutamate catabolic process
+is_a: GO:0019665 ! amino acid fermentation
+property_value: skos:narrowMatch MetaCyc:P162-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
[Term]
id: GO:0019553
-name: L-glutamate catabolic process via L-citramalate
+name: L-glutamate fermentation via L-citramalate
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of L-glutamate, via the intermediate L-citramalate." [GOC:go_curators]
synonym: "glutamate breakdown via L-citramalate" EXACT []
synonym: "glutamate degradation via L-citramalate" EXACT []
+synonym: "L-glutamate catabolic process via L-citramalate" EXACT []
xref: MetaCyc:GLUDEG-II-PWY
is_a: GO:0006538 ! L-glutamate catabolic process
+is_a: GO:0019665 ! amino acid fermentation
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
[Term]
id: GO:0019554
-name: glutamate catabolic process to oxaloacetate
+name: obsolete glutamate catabolic process to oxaloacetate
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate." [GOC:go_curators]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate." [GOC:go_curators]
+comment: The reason for obsoletion is that there is no evidence that this function/process/component exists.
synonym: "glutamate breakdown to oxaloacetate" EXACT []
synonym: "glutamate degradation to oxaloacetate" EXACT []
-is_a: GO:0006107 ! oxaloacetate metabolic process
-is_a: GO:0006536 ! glutamate metabolic process
-is_a: GO:0043649 ! dicarboxylic acid catabolic process
-is_a: GO:0043650 ! dicarboxylic acid biosynthetic process
-is_a: GO:1901606 ! alpha-amino acid catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31091" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0019555
@@ -150317,7 +156611,6 @@
xref: MetaCyc:HISDEG-PWY
is_a: GO:0006536 ! glutamate metabolic process
is_a: GO:0006548 ! L-histidine catabolic process
-is_a: GO:0043605 ! amide catabolic process
[Term]
id: GO:0019557
@@ -150407,16 +156700,18 @@
[Term]
id: GO:0019564
-name: aerobic glycerol catabolic process
+name: obsolete aerobic glycerol catabolic process
namespace: biological_process
alt_id: GO:0019565
-def: "The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen." [GOC:ai, ISBN:0198506732]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen." [GOC:ai, ISBN:0198506732]
+comment: This term was obsoleted because it represents the same process as glycerol catabolic process to glycerone phosphate ; GO:0061610.
synonym: "aerobic glycerol breakdown" EXACT []
synonym: "aerobic glycerol catabolism" EXACT []
synonym: "aerobic glycerol degradation" EXACT []
synonym: "aerobic glycerol fermentation" RELATED []
-xref: MetaCyc:PWY0-381
-is_a: GO:0019563 ! glycerol catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31214" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0061610
[Term]
id: GO:0019566
@@ -150647,19 +156942,19 @@
namespace: biological_process
def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP." [GOC:mah]
synonym: "glycerol fermentation" EXACT []
+is_a: GO:0006113 ! fermentation
is_a: GO:0019563 ! glycerol catabolic process
-is_a: GO:0019662 ! non-glycolytic fermentation
[Term]
id: GO:0019589
-name: anaerobic glycerol catabolic process to propane-1,3-diol
+name: anaerobic glycerol catabolic process to 1,3-propanediol and glycerone phosphate
namespace: biological_process
-def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol into propane-1,3-diol and water." [GOC:jl, MetaCyc:GOLPDLCAT-PWY]
+def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol into 1,3-propanediol and glycerone phosphate." [MetaCyc:GOLPDLCAT-PWY]
synonym: "glycerol fermentation to 1,3-propanediol" EXACT []
synonym: "glycerol fermentation to propane-1,3-diol" EXACT []
-xref: MetaCyc:GOLPDLCAT-PWY
-is_a: GO:0019588 ! anaerobic glycerol catabolic process
-is_a: GO:0042844 ! glycol metabolic process
+is_a: GO:0019563 ! glycerol catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31214" xsd:anyURI
[Term]
id: GO:0019590
@@ -150683,8 +156978,10 @@
synonym: "mannitol breakdown" EXACT []
synonym: "mannitol catabolism" EXACT []
synonym: "mannitol degradation" EXACT []
+xref: MetaCyc:PWY-3861
is_a: GO:0019407 ! hexitol catabolic process
is_a: GO:0019594 ! mannitol metabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-3861
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -151012,6 +157309,7 @@
synonym: "3-(3-hydroxy)phenylpropionate degradation" EXACT []
is_a: GO:0046164 ! alcohol catabolic process
is_a: GO:0072329 ! monocarboxylic acid catabolic process
+property_value: skos:broadMatch MetaCyc:HCAMHPDEG-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
[Term]
@@ -151023,7 +157321,6 @@
synonym: "atrazine degradation to urea" EXACT []
is_a: GO:0019381 ! atrazine catabolic process
is_a: GO:0019627 ! urea metabolic process
-is_a: GO:0043605 ! amide catabolic process
[Term]
id: GO:0019624
@@ -151033,6 +157330,7 @@
synonym: "atrazine breakdown to isopropylamine" EXACT []
synonym: "atrazine degradation to isopropylamine" EXACT []
is_a: GO:0019381 ! atrazine catabolic process
+property_value: skos:broadMatch MetaCyc:P141-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
[Term]
@@ -151043,6 +157341,7 @@
synonym: "atrazine breakdown to cyanuric acid" EXACT []
synonym: "atrazine degradation to cyanuric acid" EXACT []
is_a: GO:0019381 ! atrazine catabolic process
+property_value: skos:broadMatch MetaCyc:P141-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
[Term]
@@ -151066,7 +157365,6 @@
namespace: biological_process
def: "The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2." [ISBN:0198506732]
synonym: "urea metabolism" EXACT []
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0044281 ! small molecule metabolic process
is_a: GO:0071941 ! nitrogen cycle metabolic process
@@ -151241,7 +157539,13 @@
synonym: "reductive citric acid pathway" EXACT []
synonym: "reductive Kreb's cycle" EXACT []
synonym: "reductive TCA cycle" EXACT []
+xref: MetaCyc:P23-PWY
+xref: MetaCyc:P42-PWY
+xref: MetaCyc:PWY-5392
is_a: GO:0015977 ! carbon fixation
+property_value: skos:narrowMatch MetaCyc:P23-PWY
+property_value: skos:narrowMatch MetaCyc:P42-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-5392
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28429" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -151315,42 +157619,50 @@
[Term]
id: GO:0019651
-name: citrate catabolic process to diacetyl
+name: citrate fermentation to diacetyl
namespace: biological_process
-def: "The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl, yielding energy in the form of ATP." [MetaCyc:P126-PWY]
-synonym: "citrate fermentation to diacetyl" EXACT []
+def: "The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl." [PMID:30335810, PMID:38249489]
+synonym: "citrate catabolic process to diacetyl" EXACT []
synonym: "diacetyl fermentation" EXACT []
is_a: GO:0006101 ! citrate metabolic process
-is_a: GO:0019662 ! non-glycolytic fermentation
+is_a: GO:0006113 ! fermentation
is_a: GO:0042180 ! ketone metabolic process
-is_a: GO:0072352 ! tricarboxylic acid catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31218" xsd:anyURI
[Term]
id: GO:0019652
-name: lactate fermentation to propionate and acetate
+name: obsolete L-alanine fermentation to propanoate and acetate
namespace: biological_process
-def: "The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP)." [GOC:jl, MetaCyc:PROPFERM-PWY]
+def: "OBSOLETE. The anaerobic enzymatic conversion of L-alanine to acetate and propanoate." [MetaCyc:PROPFERM-PWY]
+comment: This term was obsoleted because it represents a variation of L-alanine fermentation; GO:0019667.
synonym: "acrylate pathway" EXACT []
synonym: "nonrandomizing pathway" EXACT []
synonym: "propionate fermentation" EXACT []
-xref: MetaCyc:PROPFERM-PWY
-is_a: GO:0019541 ! propionate metabolic process
-is_a: GO:0019662 ! non-glycolytic fermentation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31216" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0019667
[Term]
id: GO:0019653
-name: anaerobic purine nucleobase catabolic process
+name: purine fermentation
namespace: biological_process
-def: "The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP." [GOC:mah]
+def: "The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding acetate and CO2." [GOC:mah]
synonym: "anaerobic purine base catabolic process" EXACT [GOC:go_curators]
synonym: "anaerobic purine base catabolism" EXACT []
synonym: "anaerobic purine catabolic process" RELATED []
+synonym: "anaerobic purine nucleobase catabolic process" EXACT []
synonym: "purine base fermentation" EXACT []
-synonym: "purine fermentation" RELATED []
+xref: MetaCyc:P164-PWY
+xref: MetaCyc:PWY-5497
is_a: GO:0006113 ! fermentation
is_a: GO:0006145 ! purine nucleobase catabolic process
+property_value: skos:narrowMatch MetaCyc:P164-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-5497
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31218" xsd:anyURI
[Term]
id: GO:0019654
@@ -151387,19 +157699,19 @@
[Term]
id: GO:0019656
-name: glucose catabolic process to D-lactate and ethanol
+name: heterolactic fermentation
namespace: biological_process
def: "The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule." [GOC:jl, MetaCyc:P122-PWY]
+synonym: "glucose catabolic process to D-lactate and ethanol" RELATED []
synonym: "glucose fermentation to D-lactate and ethanol" EXACT []
synonym: "heterofermentation" EXACT []
synonym: "heterofermentative lactate fermentation" EXACT []
synonym: "heterofermentative pathway" EXACT []
synonym: "heterolactate fermentation" EXACT []
-synonym: "heterolactic fermentation" EXACT []
xref: MetaCyc:P122-PWY
is_a: GO:0006067 ! ethanol metabolic process
is_a: GO:0019659 ! glucose catabolic process to lactate
-is_a: GO:0019662 ! non-glycolytic fermentation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
[Term]
id: GO:0019657
@@ -151426,13 +157738,14 @@
xref: MetaCyc:P124-PWY
is_a: GO:0006083 ! acetate metabolic process
is_a: GO:0019659 ! glucose catabolic process to lactate
-is_a: GO:0019662 ! non-glycolytic fermentation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
[Term]
id: GO:0019659
name: glucose catabolic process to lactate
namespace: biological_process
def: "The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, and possibly ethanol, yielding energy in the form of adenosine triphosphate (ATP)." [GOC:jl]
+subset: gocheck_do_not_annotate
synonym: "glucose fermentation to lactate" EXACT []
synonym: "lactate fermentation" EXACT []
xref: Wikipedia:Lactic_acid_fermentation
@@ -151447,32 +157760,36 @@
def: "The fermentation process resulting in the oxygen-independent conversion of pyruvate to reduced end products (e.g., lactate, ethanol, and acetate), accompanied by the concomitant oxidation of NADH to NAD." [GOC:curators]
synonym: "glycolytic fermentation" RELATED []
xref: MetaCyc:Pyruvate-Degradation
+is_a: GO:0006113 ! fermentation
is_a: GO:0042867 ! pyruvate catabolic process
-relationship: part_of GO:0006113 ! fermentation
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
[Term]
id: GO:0019661
-name: glucose catabolic process to lactate via pyruvate
+name: homolactic fermentation
namespace: biological_process
def: "The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP)." [GOC:jl]
-synonym: "glucose fermentation to lactate via pyruvate" EXACT []
+synonym: "glucose catabolic process to lactate via pyruvate" RELATED []
+synonym: "glucose fermentation to lactate via pyruvate" RELATED []
synonym: "homofermentation" EXACT []
synonym: "homofermentative lactate fermentation" EXACT []
synonym: "homofermentative pathway" EXACT []
synonym: "homolactate fermentation" EXACT []
-synonym: "homolactic fermentation" EXACT [ISBN:0716720094]
xref: MetaCyc:ANAEROFRUCAT-PWY
is_a: GO:0019659 ! glucose catabolic process to lactate
relationship: has_part GO:0019246 ! L(+)-lactate biosynthetic process from pyruvate
relationship: has_part GO:0061621 ! canonical glycolysis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
[Term]
id: GO:0019662
-name: non-glycolytic fermentation
+name: obsolete non-glycolytic fermentation
namespace: biological_process
-def: "Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway." [GOC:jl]
-is_a: GO:0006113 ! fermentation
+def: "OBSOLETE. Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway." [GOC:jl]
+comment: This term was obsoleted because it was defined negatively.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31214" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0006113
[Term]
id: GO:0019664
@@ -151498,12 +157815,13 @@
[Term]
id: GO:0019665
-name: anaerobic amino acid catabolic process
+name: amino acid fermentation
namespace: biological_process
-def: "The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP." [GOC:curators, GOC:jl]
-synonym: "amino acid fermentation" EXACT []
+def: "The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids to ammonia, CO2, H2, acetate and short chain fatty acids, under anoxic conditions." [GOC:curators, GOC:jl]
+synonym: "anaerobic amino acid catabolic process" EXACT []
is_a: GO:0006113 ! fermentation
is_a: GO:0009063 ! amino acid catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31218" xsd:anyURI
[Term]
id: GO:0019666
@@ -151517,14 +157835,19 @@
[Term]
id: GO:0019667
-name: anaerobic L-alanine catabolic process
+name: L-alanine fermentation
namespace: biological_process
-def: "The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding energy in the form of ATP." [GOC:jl]
-synonym: "L-alanine fermentation" EXACT []
-is_a: GO:0019665 ! anaerobic amino acid catabolic process
+def: "The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding acetylCoA. AcetylCoA can be further converted to ATP." [GOC:jl]
+synonym: "anaerobic L-alanine catabolic process" EXACT []
+xref: MetaCyc:PROPFERM-PWY
+xref: MetaCyc:PWY-8188
+xref: MetaCyc:PWY-8189
+is_a: GO:0019665 ! amino acid fermentation
is_a: GO:0042853 ! L-alanine catabolic process
-relationship: part_of GO:0019668 ! anaerobic catabolism of pairs of amino acids
+property_value: skos:narrowMatch MetaCyc:PWY-8188
+property_value: skos:narrowMatch MetaCyc:PWY-8189
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31218" xsd:anyURI
[Term]
id: GO:0019668
@@ -151534,30 +157857,31 @@
synonym: "cofermentation of pairs of amino acids" EXACT []
synonym: "Stickland reaction" NARROW []
xref: MetaCyc:Amino-Acid-Fermentation
-is_a: GO:0019665 ! anaerobic amino acid catabolic process
+is_a: GO:0019665 ! amino acid fermentation
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
[Term]
id: GO:0019669
-name: anaerobic glycine catabolic process
+name: glycine fermentation
namespace: biological_process
-def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glycine, yielding energy in the form of ATP." [GOC:jl]
-synonym: "glycine fermentation" EXACT []
+def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glycine, yielding energy in the form of ATP." [MetaCyc:PWY-8015]
+synonym: "anaerobic glycine catabolic process" EXACT []
xref: MetaCyc:PWY-8015
is_a: GO:0006546 ! glycine catabolic process
-is_a: GO:0019665 ! anaerobic amino acid catabolic process
-relationship: part_of GO:0019668 ! anaerobic catabolism of pairs of amino acids
+is_a: GO:0019665 ! amino acid fermentation
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31218" xsd:anyURI
[Term]
id: GO:0019670
-name: anaerobic L-glutamate catabolic process
+name: obsolete anaerobic L-glutamate catabolic process
namespace: biological_process
-def: "The anaerobic chemical reactions and pathways resulting in the breakdown of L-glutamate, yielding energy in the form of ATP." [GOC:jl]
+def: "OBSOLETE. The anaerobic chemical reactions and pathways resulting in the breakdown of L-glutamate, yielding energy in the form of ATP." [GOC:jl]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
synonym: "glutamate fermentation" EXACT []
-is_a: GO:0006538 ! L-glutamate catabolic process
-is_a: GO:0019665 ! anaerobic amino acid catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0019671
@@ -151574,10 +157898,13 @@
[Term]
id: GO:0019672
-name: ethanol-acetate fermentation to butyrate and caproate
+name: acetyl-CoA fermentation to butyrate
namespace: biological_process
-def: "The anaerobic chemical reactions and pathways resulting in the breakdown of ethanol and acetate to butyrate and caproate, yielding energy in the form of ATP." [MetaCyc:P127-PWY]
-is_a: GO:0019662 ! non-glycolytic fermentation
+def: "The anaerobic chemical reactions and pathways resulting in the breakdown of acetyl-CoA to butyrate, yielding energy in the form of ATP. Butanoate is secreted by the cell." [MetaCyc:PWY-5676]
+xref: MetaCyc:PWY-5676
+is_a: GO:0006113 ! fermentation
+property_value: skos:exactMatch MetaCyc:PWY-5676
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
[Term]
id: GO:0019673
@@ -151630,9 +157957,17 @@
def: "The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen." [MetaCyc:AMMASSIM-PWY]
synonym: "glutamate metabolic process via glutamine and ammonia" EXACT []
synonym: "glutamate metabolism via glutamine and ammonia" EXACT []
+xref: MetaCyc:AMMASSIM-PWY
+xref: MetaCyc:PWY-3282
+xref: MetaCyc:PWY-6963
+xref: MetaCyc:PWY-6964
is_a: GO:0006536 ! glutamate metabolic process
is_a: GO:0006541 ! glutamine metabolic process
is_a: GO:0019740 ! nitrogen utilization
+property_value: skos:narrowMatch MetaCyc:AMMASSIM-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-3282
+property_value: skos:narrowMatch MetaCyc:PWY-6963
+property_value: skos:narrowMatch MetaCyc:PWY-6964
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -151920,6 +158255,9 @@
xref: EC:2.1.1.322
xref: RHEA:48116
is_a: GO:0016274 ! protein-arginine N-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.322
+property_value: skos:exactMatch RHEA:48116
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019703
@@ -151951,6 +158289,8 @@
xref: RHEA:59736
is_a: GO:0019107 ! myristoyltransferase activity
is_a: GO:0019707 ! protein-cysteine S-acyltransferase activity
+property_value: skos:exactMatch RHEA:59736
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019706
@@ -151969,18 +158309,21 @@
xref: RHEA:36683
is_a: GO:0016409 ! palmitoyltransferase activity
is_a: GO:0019707 ! protein-cysteine S-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.225
+property_value: skos:exactMatch RHEA:36683
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019707
name: protein-cysteine S-acyltransferase activity
namespace: molecular_function
def: "Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule." [GOC:ai, RHEA:63372]
-xref: Reactome:R-HSA-158832 "The acetyl group from acetyl-CoA is transferred to NAT2"
-xref: Reactome:R-HSA-174959 "The acetyl group from acetyl-CoA is transferred to NAT1"
xref: RHEA:63372
is_a: GO:0016417 ! S-acyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch RHEA:63372
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18882" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019708
@@ -152581,6 +158924,7 @@
def: "Catalysis of the transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y = Y-FAT10 + X, where both X-FAT10 and Y-FAT10 are covalent linkages." [GOC:dph, GOC:mah, PMID:12826404]
synonym: "FAT10 conjugating enzyme activity" NARROW []
is_a: GO:0019787 ! ubiquitin-like protein transferase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30964" xsd:anyURI
[Term]
id: GO:0019776
@@ -152638,7 +158982,9 @@
synonym: "RUB1 activating enzyme activity" EXACT []
xref: EC:6.2.1.64
is_a: GO:0008641 ! ubiquitin-like modifier activating enzyme activity
+property_value: skos:exactMatch EC:6.2.1.64
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22387" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019782
@@ -152754,6 +159100,7 @@
xref: Reactome:R-HSA-8952638 "AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex"
xref: Reactome:R-HSA-8956025 "AcM-UBE2M transfers NEDD8 to CUL9:RBX1"
is_a: GO:0019787 ! ubiquitin-like protein transferase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30964" xsd:anyURI
[Term]
id: GO:0019789
@@ -152898,7 +159245,6 @@
xref: Reactome:R-HSA-6804468 "PIAS1 SUMOylates SP3 with SUMO2"
xref: Reactome:R-HSA-6804485 "PIAS1 SUMOylates L3MBTL2 with SUMO2"
xref: Reactome:R-HSA-8956365 "ZBED1 (DREF) SUMOylates CHD3 with SUMO1"
-xref: Reactome:R-HSA-9926476 "UBE2I sumoylates MITF-M"
is_a: GO:0019787 ! ubiquitin-like protein transferase activity
[Term]
@@ -152997,6 +159343,9 @@
xref: RHEA:22872
is_a: GO:0019798 ! procollagen-proline dioxygenase activity
is_a: GO:0031544 ! peptidyl-proline 3-dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.7
+property_value: skos:exactMatch RHEA:22872
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019798
@@ -153022,6 +159371,9 @@
xref: MetaCyc:TUBULIN-N-ACETYLTRANSFERASE-RXN
xref: RHEA:15277
is_a: GO:0061733 ! protein-lysine-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.108
+property_value: skos:exactMatch RHEA:15277
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019800
@@ -153097,7 +159449,9 @@
synonym: "bromoperoxidase activity" EXACT []
xref: EC:1.11.1.18
is_a: GO:0140905 ! haloperoxidase activity
+property_value: skos:exactMatch EC:1.11.1.18
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23587" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019807
@@ -153111,9 +159465,12 @@
synonym: "N-acyl-L-aspartate amidohydrolase activity" RELATED [EC:3.5.1.15]
xref: EC:3.5.1.15
xref: MetaCyc:ASPARTOACYLASE-RXN
-xref: Reactome:R-HSA-5691507 "ASPA deacetylates NAASP to acetate and L-aspartate"
+xref: Reactome:R-HSA-5691507 "ASPA deacetylates NAA to acetate and L-aspartate"
xref: RHEA:10872
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.15
+property_value: skos:exactMatch RHEA:10872
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019808
@@ -153364,7 +159721,7 @@
namespace: molecular_function
def: "Binds to and stops, prevents or reduces the activity of phospholipase A2." [GOC:ai]
is_a: GO:0004859 ! phospholipase inhibitor activity
-relationship: negatively_regulates GO:0004623 ! phospholipase A2 activity
+relationship: negatively_regulates GO:0004623 ! A2-type glycerophospholipase activity
[Term]
id: GO:0019835
@@ -153577,7 +159934,6 @@
name: calcium channel inhibitor activity
namespace: molecular_function
def: "Binds to and stops, prevents, or reduces the activity of a calcium channel." [GOC:mah]
-xref: Reactome:R-HSA-400046 "L-type Calcium Channels close in pancreatic beta cells"
is_a: GO:0005246 ! calcium channel regulator activity
is_a: GO:0008200 ! ion channel inhibitor activity
relationship: negatively_regulates GO:0005262 ! calcium channel activity
@@ -153705,8 +160061,6 @@
name: potassium channel inhibitor activity
namespace: molecular_function
def: "Binds to and stops, prevents, or reduces the activity of a potassium channel." [GOC:mah]
-xref: Reactome:R-HSA-381644 "ER calcium channels open in response to activated PKA"
-xref: Reactome:R-HSA-381713 "Potassium voltage-gated channels close in reponse to PKA"
is_a: GO:0008200 ! ion channel inhibitor activity
is_a: GO:0015459 ! potassium channel regulator activity
relationship: negatively_regulates GO:0005267 ! potassium channel activity
@@ -153755,6 +160109,9 @@
xref: RHEA:16225
xref: UM-BBD_reactionID:r1097
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.12
+property_value: skos:exactMatch RHEA:16225
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019875
@@ -153768,6 +160125,9 @@
xref: RHEA:21364
xref: UM-BBD_enzymeID:r1096
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.46
+property_value: skos:exactMatch RHEA:21364
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0019876
@@ -153794,9 +160154,9 @@
[Term]
id: GO:0019878
-name: lysine biosynthetic process via aminoadipic acid
+name: L-lysine biosynthetic process via aminoadipic acid
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway." [GOC:go_curators]
+def: "The chemical reactions and pathways resulting in the formation of L-lysine by the aminoadipic pathway." [GOC:go_curators]
synonym: "lysine anabolism via aminoadipic acid" EXACT []
synonym: "lysine biosynthesis, aminoadipic acid pathway" EXACT []
synonym: "lysine biosynthesis, aminoadipic pathway" EXACT []
@@ -153804,7 +160164,8 @@
synonym: "lysine biosynthetic process, aminoadipic pathway" EXACT []
synonym: "lysine formation via aminoadipic acid" EXACT []
synonym: "lysine synthesis via aminoadipic acid" EXACT []
-is_a: GO:0009085 ! lysine biosynthetic process
+is_a: GO:0009085 ! L-lysine biosynthetic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30820" xsd:anyURI
[Term]
id: GO:0019879
@@ -154429,8 +160790,8 @@
synonym: "protein degradation tagging activity" RELATED []
synonym: "protein-ligand-dependent protein catabolic process" NARROW []
synonym: "protein-ligand-dependent protein catabolism" NARROW []
+is_a: GO:0030163 ! protein catabolic process
is_a: GO:0043632 ! modification-dependent macromolecule catabolic process
-is_a: GO:0051603 ! proteolysis involved in protein catabolic process
relationship: has_part GO:0036211 ! protein modification process
[Term]
@@ -155065,7 +161426,6 @@
namespace: molecular_function
def: "Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring." [GOC:ai]
synonym: "haem binding" EXACT []
-xref: Reactome:R-HSA-9661419 "ALB binds extracellular heme"
is_a: GO:0046906 ! tetrapyrrole binding
[Term]
@@ -157831,12 +164191,14 @@
[Term]
id: GO:0021811
-name: growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration
+name: obsolete growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration
namespace: biological_process
-def: "Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+def: "OBSOLETE. Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "growth factor signaling initiating cell movement involved in cerebral cortex glial-mediated radial migration" EXACT [GOC:mtg_cardio]
synonym: "growth factor signalling initiating cell movement involved in cerebral cortex glial-mediated radial migration" EXACT []
-is_a: GO:0021807 ! motogenic signaling initiating cell movement in cerebral cortex
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0021812
@@ -157920,25 +164282,27 @@
[Term]
id: GO:0021820
-name: extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration
+name: obsolete extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration
namespace: biological_process
-def: "The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+def: "OBSOLETE. The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "extracellular matrix organisation in marginal zone involved in cerebral cortex radial glia guided migration" EXACT [GOC:mah]
synonym: "organization of extracellular matrix in the marginal zone involved in cerebral cortex glial-mediated radial migration" EXACT [GOC:dph]
-is_a: GO:0030198 ! extracellular matrix organization
-relationship: part_of GO:0021819 ! layer formation in cerebral cortex
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0021821
-name: negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination
+name: obsolete negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination
namespace: biological_process
-def: "The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+def: "OBSOLETE. The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of cell-glial cell adhesion involved in cerebral cortex lamination" EXACT []
synonym: "down-regulation of cell-glial cell adhesion involved in cerebral cortex lamination" EXACT []
synonym: "downregulation of cell-glial cell adhesion involved in cerebral cortex lamination" EXACT []
synonym: "inhibition of cell-glial cell adhesion involved in cerebral cortex lamination" NARROW []
-is_a: GO:0022408 ! negative regulation of cell-cell adhesion
-relationship: part_of GO:0021819 ! layer formation in cerebral cortex
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0021822
@@ -158033,21 +164397,22 @@
[Term]
id: GO:0021832
-name: cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions
+name: obsolete cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions
namespace: biological_process
-def: "The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
-is_a: GO:0098609 ! cell-cell adhesion
-intersection_of: GO:0098609 ! cell-cell adhesion
-intersection_of: part_of GO:0021823 ! cerebral cortex tangential migration using cell-cell interactions
-relationship: part_of GO:0021823 ! cerebral cortex tangential migration using cell-cell interactions
+def: "OBSOLETE. The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0021823
[Term]
id: GO:0021833
-name: cell-matrix adhesion involved in tangential migration using cell-cell interactions
+name: obsolete cell-matrix adhesion involved in tangential migration using cell-cell interactions
namespace: biological_process
-def: "The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex." [GO_REF:0000021, GOC:ascb_2009, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:12626695]
-is_a: GO:0031589 ! cell-substrate adhesion
-relationship: part_of GO:0021823 ! cerebral cortex tangential migration using cell-cell interactions
+def: "OBSOLETE. The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex." [GO_REF:0000021, GOC:ascb_2009, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:12626695]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0021834
@@ -158062,14 +164427,15 @@
[Term]
id: GO:0021835
-name: chemoattraction involved in embryonic olfactory bulb interneuron precursor migration
+name: obsolete chemoattraction involved in embryonic olfactory bulb interneuron precursor migration
namespace: biological_process
-def: "The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+def: "OBSOLETE. The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive chemotaxis involved in embryonic olfactory bulb interneuron precursor migration" EXACT [GOC:mah]
-is_a: GO:0050918 ! positive chemotaxis
-intersection_of: GO:0050918 ! positive chemotaxis
-intersection_of: part_of GO:0021831 ! embryonic olfactory bulb interneuron precursor migration
-relationship: part_of GO:0021831 ! embryonic olfactory bulb interneuron precursor migration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0021831
+consider: GO:0050918
[Term]
id: GO:0021836
@@ -158084,31 +164450,32 @@
[Term]
id: GO:0021837
-name: motogenic signaling involved in postnatal olfactory bulb interneuron migration
+name: obsolete motogenic signaling involved in postnatal olfactory bulb interneuron migration
namespace: biological_process
-def: "The signaling that results in the stimulation of cell movement in the rostral migratory stream." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+def: "OBSOLETE. The signaling that results in the stimulation of cell movement in the rostral migratory stream." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "motogenic signalling involved in postnatal olfactory bulb interneuron migration" EXACT []
-is_a: GO:0007154 ! cell communication
-is_a: GO:0023052 ! signaling
-relationship: part_of GO:0021827 ! postnatal olfactory bulb interneuron migration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0021838
-name: motogenic signaling involved in interneuron migration from the subpallium to the cortex
+name: obsolete motogenic signaling involved in interneuron migration from the subpallium to the cortex
namespace: biological_process
-def: "The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+def: "OBSOLETE. The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "motogenic signalling involved in interneuron migration from the subpallium to the cortex" EXACT []
-is_a: GO:0007154 ! cell communication
-is_a: GO:0023052 ! signaling
-relationship: part_of GO:0021830 ! interneuron migration from the subpallium to the cortex
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0021839
-name: interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex
+name: obsolete interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex
namespace: biological_process
-def: "The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
-is_a: GO:0031589 ! cell-substrate adhesion
-relationship: part_of GO:0021830 ! interneuron migration from the subpallium to the cortex
+def: "OBSOLETE. The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0021840
@@ -158120,14 +164487,15 @@
[Term]
id: GO:0021841
-name: chemoattraction involved in interneuron migration from the subpallium to the cortex
+name: obsolete chemoattraction involved in interneuron migration from the subpallium to the cortex
namespace: biological_process
-def: "The creation and reception of signals that result in the movement of interneurons toward the signal, where this process is involved in migration from the subpallium to the cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+def: "OBSOLETE. The creation and reception of signals that result in the movement of interneurons toward the signal, where this process is involved in migration from the subpallium to the cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive chemotaxis involved in interneuron migration from the subpallium to the cortex" EXACT [GOC:mah]
-is_a: GO:0050918 ! positive chemotaxis
-intersection_of: GO:0050918 ! positive chemotaxis
-intersection_of: part_of GO:0021830 ! interneuron migration from the subpallium to the cortex
-relationship: part_of GO:0021840 ! directional guidance of interneurons involved in migration from the subpallium to the cortex
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0021830
+consider: GO:0050918
[Term]
id: GO:0021842
@@ -158149,19 +164517,21 @@
[Term]
id: GO:0021844
-name: interneuron sorting involved in substrate-independent cerebral cortex tangential migration
+name: obsolete interneuron sorting involved in substrate-independent cerebral cortex tangential migration
namespace: biological_process
-def: "The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
-is_a: GO:0042330 ! taxis
-relationship: part_of GO:0021843 ! substrate-independent telencephalic tangential interneuron migration
+def: "OBSOLETE. The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0021845
-name: neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration
+name: obsolete neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration
namespace: biological_process
-def: "The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
-is_a: GO:0030334 ! regulation of cell migration
-relationship: part_of GO:0021843 ! substrate-independent telencephalic tangential interneuron migration
+def: "OBSOLETE. The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0021846
@@ -158405,25 +164775,27 @@
[Term]
id: GO:0021875
-name: fibroblast growth factor receptor signaling pathway involved in forebrain neuroblast division
+name: obsolete fibroblast growth factor receptor signaling pathway involved in forebrain neuroblast division
namespace: biological_process
-def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the self renewal of neuroblasts in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447]
+def: "OBSOLETE. The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the self renewal of neuroblasts in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "fibroblast growth factor receptor signalling pathway in forebrain neuroblast division" EXACT []
-is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway
-intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway
-intersection_of: part_of GO:0021873 ! forebrain neuroblast division
-relationship: part_of GO:0021873 ! forebrain neuroblast division
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0008543
+consider: GO:0021873
[Term]
id: GO:0021876
-name: Notch signaling pathway involved in forebrain neuroblast division
+name: obsolete Notch signaling pathway involved in forebrain neuroblast division
namespace: biological_process
-def: "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447]
+def: "OBSOLETE. The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "Notch signalling pathway in forebrain neuroblast division" EXACT []
-is_a: GO:0007219 ! Notch signaling pathway
-intersection_of: GO:0007219 ! Notch signaling pathway
-intersection_of: part_of GO:0021873 ! forebrain neuroblast division
-relationship: part_of GO:0021873 ! forebrain neuroblast division
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007219
+consider: GO:0021873
[Term]
id: GO:0021877
@@ -158684,14 +165056,15 @@
[Term]
id: GO:0021907
-name: fibroblast growth factor receptor signaling pathway involved in spinal cord anterior/posterior pattern formation
+name: obsolete fibroblast growth factor receptor signaling pathway involved in spinal cord anterior/posterior pattern formation
namespace: biological_process
-def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]
+def: "OBSOLETE. The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "fibroblast growth factor receptor signalling pathway in spinal cord anterior-posterior patterning" EXACT []
-is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway
-intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway
-intersection_of: part_of GO:0021512 ! spinal cord anterior/posterior patterning
-relationship: part_of GO:0021512 ! spinal cord anterior/posterior patterning
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0008543
+consider: GO:0021512
[Term]
id: GO:0021908
@@ -158758,9 +165131,10 @@
[Term]
id: GO:0021914
-name: negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
+name: obsolete negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
namespace: biological_process
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:11262869]
+def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:11262869]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of smoothened signaling pathway in ventral spinal cord patterning" EXACT []
synonym: "down-regulation of smoothened signaling pathway in ventral spinal cord patterning" EXACT []
synonym: "downregulation of smoothened signaling pathway in ventral spinal cord patterning" EXACT []
@@ -158768,11 +165142,10 @@
synonym: "negative regulation of hedgehog signaling pathway involved in ventral spinal cord patterning" EXACT [GOC:bf, GOC:ecd]
synonym: "negative regulation of hh signaling pathway involved in ventral spinal cord patterning" EXACT [GOC:bf, GOC:ecd]
synonym: "negative regulation of smoothened signalling pathway in ventral spinal cord patterning" EXACT []
-is_a: GO:0045879 ! negative regulation of smoothened signaling pathway
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0021910 ! smoothened signaling pathway involved in ventral spinal cord patterning
-relationship: negatively_regulates GO:0021910 ! smoothened signaling pathway involved in ventral spinal cord patterning
-relationship: part_of GO:0021513 ! spinal cord dorsal/ventral patterning
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0021513
+consider: GO:0045879
[Term]
id: GO:0021915
@@ -158974,22 +165347,25 @@
[Term]
id: GO:0021938
-name: smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
+name: obsolete smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
namespace: biological_process
-def: "The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in cerebellar granule cells that contributes to the regulation of proliferation of the cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:15157725]
+def: "OBSOLETE. The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in cerebellar granule cells that contributes to the regulation of proliferation of the cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:15157725]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "hedgehog signaling pathway involved in regulation of granule cell precursor cell proliferation" EXACT [GOC:bf, GOC:ecd]
synonym: "hh signaling pathway involved in regulation of granule cell precursor cell proliferation" EXACT [GOC:bf, GOC:ecd]
synonym: "smoothened signalling pathway in regulation of granule cell precursor cell proliferation" EXACT []
-is_a: GO:0007224 ! smoothened signaling pathway
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0021939
-name: extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation
+name: obsolete extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation
namespace: biological_process
-def: "The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725]
+def: "OBSOLETE. The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "extracellular matrix-granule cell signalling involved in regulation of granule cell precursor proliferation" EXACT []
-is_a: GO:0035426 ! extracellular matrix-cell signaling
-relationship: part_of GO:0021941 ! negative regulation of cerebellar granule cell precursor proliferation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0021940
@@ -159096,25 +165472,27 @@
[Term]
id: GO:0021950
-name: chemorepulsion involved in precerebellar neuron migration
+name: obsolete chemorepulsion involved in precerebellar neuron migration
namespace: biological_process
-def: "The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725]
+def: "OBSOLETE. The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "negative chemotaxis involved in precerebellar neuron migration" EXACT [GOC:mah]
-is_a: GO:0050919 ! negative chemotaxis
-intersection_of: GO:0050919 ! negative chemotaxis
-intersection_of: part_of GO:0021949 ! brainstem precerebellar neuron precursor migration
-relationship: part_of GO:0021949 ! brainstem precerebellar neuron precursor migration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0021949
+consider: GO:0050919
[Term]
id: GO:0021951
-name: chemoattraction involved in precerebellar neuron migration
+name: obsolete chemoattraction involved in precerebellar neuron migration
namespace: biological_process
-def: "The creation and reception of signals that guide a precerebellar neuron towards their signals, where this process is involved in tangential migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725]
+def: "OBSOLETE. The creation and reception of signals that guide a precerebellar neuron towards their signals, where this process is involved in tangential migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive chemotaxis involved in precerebellar neuron migration" EXACT [GOC:mah]
-is_a: GO:0050918 ! positive chemotaxis
-intersection_of: GO:0050918 ! positive chemotaxis
-intersection_of: part_of GO:0021949 ! brainstem precerebellar neuron precursor migration
-relationship: part_of GO:0021949 ! brainstem precerebellar neuron precursor migration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0021949
+consider: GO:0050918
[Term]
id: GO:0021952
@@ -159451,13 +165829,14 @@
[Term]
id: GO:0021992
-name: cell proliferation involved in neural plate elongation
+name: obsolete cell proliferation involved in neural plate elongation
namespace: biological_process
-def: "The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15806586]
-is_a: GO:0061351 ! neural precursor cell proliferation
-intersection_of: GO:0008283 ! cell population proliferation
-intersection_of: part_of GO:0014022 ! neural plate elongation
-relationship: part_of GO:0014022 ! neural plate elongation
+def: "OBSOLETE. The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15806586]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0008283
+consider: GO:0014022
[Term]
id: GO:0021993
@@ -159763,25 +166142,27 @@
[Term]
id: GO:0022025
-name: leukemia inhibitory factor signaling pathway involved in forebrain neuron fate commitment
+name: obsolete leukemia inhibitory factor signaling pathway involved in forebrain neuron fate commitment
namespace: biological_process
-def: "The series of molecular signals initiated by the binding of leukemia inhibitory factor to its receptor on the surface of the target cell, that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:signaling]
+def: "OBSOLETE. The series of molecular signals initiated by the binding of leukemia inhibitory factor to its receptor on the surface of the target cell, that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:signaling]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "leukemia inhibitory factor signalling pathway involved in forebrain neuron fate commitment" EXACT []
-is_a: GO:0048861 ! leukemia inhibitory factor signaling pathway
-intersection_of: GO:0048861 ! leukemia inhibitory factor signaling pathway
-intersection_of: part_of GO:0021877 ! forebrain neuron fate commitment
-relationship: part_of GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0021877
+consider: GO:0048861
[Term]
id: GO:0022026
-name: epidermal growth factor signaling pathway involved in forebrain neuron fate commitment
+name: obsolete epidermal growth factor signaling pathway involved in forebrain neuron fate commitment
namespace: biological_process
-def: "The series of molecular signals generated as a consequence of a epidermal growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
+def: "OBSOLETE. The series of molecular signals generated as a consequence of a epidermal growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "epidermal growth factor signalling pathway involved in forebrain neuron fate commitment" EXACT []
-is_a: GO:0007173 ! epidermal growth factor receptor signaling pathway
-intersection_of: GO:0007173 ! epidermal growth factor receptor signaling pathway
-intersection_of: part_of GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain
-relationship: part_of GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007173
+consider: GO:0021898
[Term]
id: GO:0022027
@@ -160036,7 +166417,9 @@
id: GO:0022414
name: reproductive process
namespace: biological_process
+alt_id: GO:0019952
alt_id: GO:0044702
+alt_id: GO:0050876
def: "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:dph, GOC:isa_complete]
subset: gocheck_do_not_annotate
subset: goslim_agr
@@ -160071,7 +166454,6 @@
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29105" xsd:anyURI
is_obsolete: true
replaced_by: GO:0051604
-consider: GO:0044183
[Term]
id: GO:0022600
@@ -160432,6 +166814,7 @@
def: "Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged." [GOC:mtg_transport, ISBN:0815340729]
is_a: GO:0015081 ! sodium ion transmembrane transporter activity
is_a: GO:0022810 ! membrane potential driven uniporter activity
+property_value: skos:broadMatch RHEA:34963
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
[Term]
@@ -160441,6 +166824,7 @@
def: "Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged." [GOC:mtg_transport, ISBN:0815340729]
is_a: GO:0015079 ! potassium ion transmembrane transporter activity
is_a: GO:0022810 ! membrane potential driven uniporter activity
+property_value: skos:broadMatch RHEA:29463
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
[Term]
@@ -160559,15 +166943,6 @@
name: narrow pore channel activity
namespace: molecular_function
def: "Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated." [GOC:mtg_transport, ISBN:0815340729]
-xref: Reactome:R-HSA-1855161 "I(1,3,4,5,6)P5 transports from the nucleus to the cytosol"
-xref: Reactome:R-HSA-1855168 "I(1,3,4,5)P4 transports from the cytosol to the nucleus"
-xref: Reactome:R-HSA-1855173 "5-PP-IP4 transports from the nucleus to the cytosol"
-xref: Reactome:R-HSA-1855188 "IP6 transports from the cytosol to the nucleus"
-xref: Reactome:R-HSA-1855190 "I(1,4,5)P3 transports from the cytosol to the nucleus"
-xref: Reactome:R-HSA-1855201 "I(1,3,4,6)P4 transports from the cytosol to the nucleus"
-xref: Reactome:R-HSA-1855203 "5-PP-IP5 transports from the nucleus to the cytosol"
-xref: Reactome:R-HSA-1855212 "1/3-PP-IP5 transports from the cytosol to the nucleus"
-xref: Reactome:R-HSA-1855220 "(PP)2-IP4 transports from the nucleus to the cytosol"
is_a: GO:0015267 ! channel activity
[Term]
@@ -160708,7 +167083,6 @@
xref: Reactome:R-HSA-5671707 "Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA"
xref: Reactome:R-HSA-6784434 "An unknown carrier transports cytosolic glyoxylate to the peroxisome"
xref: Reactome:R-HSA-6784436 "An unknown carrier transports mitochondrial glyoxylate to the cytosol"
-xref: Reactome:R-HSA-8954513 "NAASP translocates from mitochondrial matrix to cytosol"
is_a: GO:0005215 ! transporter activity
relationship: part_of GO:0055085 ! transmembrane transport
@@ -160782,10 +167156,14 @@
synonym: "sorbose PTS transporter activity" EXACT []
xref: EC:2.7.1.206
xref: MetaCyc:RXN-15094
+xref: RHEA:49296
is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
is_a: GO:0055056 ! D-glucose transmembrane transporter activity
+property_value: skos:exactMatch EC:2.7.1.206
+property_value: skos:narrowMatch RHEA:49296
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17289" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0022872
@@ -160851,6 +167229,8 @@
xref: RHEA:49236
is_a: GO:0008515 ! sucrose transmembrane transporter activity
is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
+property_value: skos:exactMatch RHEA:49236
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0022879
@@ -160911,7 +167291,6 @@
name: bacteriocin transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of a bacteriocin from one side of a membrane to the other." [GOC:mtg_transport, ISBN:0815340729]
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:0042910 ! xenobiotic transmembrane transporter activity
relationship: part_of GO:0043213 ! bacteriocin transport
@@ -162203,7 +168582,9 @@
synonym: "primary-amine:acceptor oxidoreductase (deaminating)" RELATED []
xref: RHEA:51128
is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors
+property_value: skos:exactMatch RHEA:51128
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21650" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030059
@@ -162216,6 +168597,9 @@
xref: MetaCyc:ARALKYLAMINE-DEHYDROGENASE-RXN
xref: RHEA:47796
is_a: GO:0052877 ! oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor
+property_value: skos:exactMatch EC:1.4.9.2
+property_value: skos:exactMatch RHEA:47796
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030060
@@ -162242,6 +168626,9 @@
xref: RHEA:21432
is_a: GO:0016615 ! malate dehydrogenase activity
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.37
+property_value: skos:exactMatch RHEA:21432
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030061
@@ -162346,6 +168733,7 @@
def: "The regulated release of a peptide hormone from a cell." [GOC:mah]
is_a: GO:0002790 ! peptide secretion
is_a: GO:0046879 ! hormone secretion
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0030073
@@ -163034,12 +169422,14 @@
synonym: "uridine diphosphoacetylglucosamine-alpha-mannoside beta1->6-acetylglucosaminyltransferase activity" RELATED [EC:2.4.1.155]
xref: EC:2.4.1.155
xref: MetaCyc:2.4.1.155-RXN
-xref: Reactome:R-HSA-8932427 "MGAT5B transfers GlcNAc from UDP-GlcNAc to GlcNAc-Man-DAG1"
xref: Reactome:R-HSA-9696980 "Spike trimer glycoside chains get additional branches"
xref: Reactome:R-HSA-975916 "Addition of GlcNAc to position 5 by MGAT5"
xref: RHEA:16921
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.155
+property_value: skos:exactMatch RHEA:16921
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030145
@@ -163085,9 +169475,15 @@
synonym: "sphingolipid formation" EXACT []
synonym: "sphingolipid synthesis" EXACT []
xref: MetaCyc:PWY-5129
+xref: MetaCyc:PWY-7277
+xref: MetaCyc:SPHINGOLIPID-SYN-PWY
xref: Reactome:R-HSA-1660661 "Sphingolipid de novo biosynthesis"
is_a: GO:0006665 ! sphingolipid metabolic process
-is_a: GO:0046467 ! membrane lipid biosynthetic process
+is_a: GO:0008610 ! lipid biosynthetic process
+property_value: skos:narrowMatch MetaCyc:PWY-5129
+property_value: skos:narrowMatch MetaCyc:PWY-7277
+property_value: skos:narrowMatch MetaCyc:SPHINGOLIPID-SYN-PWY
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31178" xsd:anyURI
[Term]
id: GO:0030149
@@ -163099,7 +169495,7 @@
synonym: "sphingolipid degradation" EXACT []
xref: Reactome:R-HSA-9845614 "Sphingolipid catabolism"
is_a: GO:0006665 ! sphingolipid metabolic process
-is_a: GO:0046466 ! membrane lipid catabolic process
+is_a: GO:0016042 ! lipid catabolic process
[Term]
id: GO:0030150
@@ -163111,7 +169507,7 @@
synonym: "protein transport into mitochondrial matrix" EXACT []
is_a: GO:0070585 ! protein localization to mitochondrion
is_a: GO:0071806 ! protein transmembrane transport
-is_a: GO:0072655 ! establishment of protein localization to mitochondrion
+is_a: GO:0072594 ! establishment of protein localization to organelle
property_value: term_tracker_item "/github.com/geneontology/go-ontology/issues/29962" xsd:anyURI
[Term]
@@ -163207,6 +169603,9 @@
xref: RHEA:50192
is_a: GO:0035252 ! UDP-xylosyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.4.2.26
+property_value: skos:exactMatch RHEA:50192
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030159
@@ -163542,7 +169941,6 @@
synonym: "melatonin metabolism" EXACT []
is_a: GO:0042430 ! indole-containing compound metabolic process
is_a: GO:0042445 ! hormone metabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0030187
@@ -163556,7 +169954,6 @@
is_a: GO:0030186 ! melatonin metabolic process
is_a: GO:0042435 ! indole-containing compound biosynthetic process
is_a: GO:0042446 ! hormone biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
[Term]
id: GO:0030188
@@ -163679,6 +170076,9 @@
xref: MetaCyc:CYANIDE-HYDRATASE-RXN
xref: RHEA:21720
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.66
+property_value: skos:exactMatch RHEA:21720
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030197
@@ -163823,8 +170223,12 @@
synonym: "chondroitin sulfate degradation" EXACT []
synonym: "chondroitin sulphate catabolic process" EXACT []
synonym: "chondroitin sulphate catabolism" EXACT []
+xref: MetaCyc:PWY-6572
+xref: MetaCyc:PWY-6573
is_a: GO:0030167 ! proteoglycan catabolic process
is_a: GO:0050654 ! chondroitin sulfate proteoglycan metabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-6572
+property_value: skos:narrowMatch MetaCyc:PWY-6573
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28977" xsd:anyURI
@@ -163862,8 +170266,12 @@
synonym: "dermatan sulfate degradation" EXACT []
synonym: "dermatan sulphate catabolic process" EXACT []
synonym: "dermatan sulphate catabolism" EXACT []
+xref: MetaCyc:PWY-6576
+xref: MetaCyc:PWY-7646
is_a: GO:0030167 ! proteoglycan catabolic process
is_a: GO:0050655 ! dermatan sulfate proteoglycan metabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-6576
+property_value: skos:narrowMatch MetaCyc:PWY-7646
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28977" xsd:anyURI
@@ -164435,8 +170843,8 @@
is_a: GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway
is_a: GO:0016056 ! G protein-coupled opsin signaling pathway
intersection_of: GO:0016056 ! G protein-coupled opsin signaling pathway
-intersection_of: has_part GO:0004629 ! phospholipase C activity
-relationship: has_part GO:0004629 ! phospholipase C activity
+intersection_of: has_part GO:0004629 ! C-type glycerophospholipase activity
+relationship: has_part GO:0004629 ! C-type glycerophospholipase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27415" xsd:anyURI
[Term]
@@ -164454,7 +170862,11 @@
xref: MetaCyc:QUINATE-5-DEHYDROGENASE-RXN
xref: RHEA:22364
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.1.1.282
+property_value: skos:exactMatch EC:1.1.1.24
+property_value: skos:exactMatch RHEA:22364
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030267
@@ -164470,7 +170882,10 @@
xref: RHEA:10992
xref: Wikipedia:Glyoxylate_reductase_(NADP+)
is_a: GO:0106345 ! glyoxylate reductase activity
+property_value: skos:exactMatch EC:1.1.1.79
+property_value: skos:exactMatch RHEA:10992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030268
@@ -164487,6 +170902,9 @@
xref: RHEA:16721
xref: UM-BBD_reactionID:r0348
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.98.1
+property_value: skos:exactMatch RHEA:16721
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030269
@@ -164506,7 +170924,10 @@
is_a: GO:0008172 ! S-methyltransferase activity
is_a: GO:0015081 ! sodium ion transmembrane transporter activity
is_a: GO:0042086 ! 5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity
+property_value: skos:exactMatch EC:7.2.1.4
+property_value: skos:exactMatch RHEA:53492
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28647" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030270
@@ -164526,6 +170947,9 @@
xref: RHEA:18061
xref: UM-BBD_reactionID:r0346
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.101
+property_value: skos:exactMatch RHEA:18061
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030271
@@ -164561,6 +170985,9 @@
xref: Reactome:R-HSA-6801342 "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG"
xref: RHEA:10488
is_a: GO:0016882 ! cyclo-ligase activity
+property_value: skos:exactMatch EC:6.3.3.2
+property_value: skos:exactMatch RHEA:10488
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030273
@@ -164659,6 +171086,7 @@
namespace: molecular_function
def: "OBSOLETE. Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+." [EC:1.1.1.51]
comment: This term was obsoleted because it is an unnecessary grouing class.
+xref: Reactome:R-HSA-193064 "HSD17B3-like proteins reducde ANDST to TEST"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28298" xsd:anyURI
is_obsolete: true
consider: GO:0047035
@@ -164860,10 +171288,12 @@
id: GO:0030305
name: heparanase activity
namespace: molecular_function
-def: "Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains." [PMID:10916150]
-synonym: "heparinase activity" RELATED []
+def: "Catalysis of the endohydrolysis of (1->4)-beta-D-glycosidic bonds of heparan sulfate chains in heparan sulfate proteoglycan." [EC:3.2.1.166, PMID:10916150]
+xref: EC:3.2.1.166
xref: Reactome:R-HSA-1667005 "Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome)"
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.166
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0030307
@@ -165202,7 +171632,10 @@
xref: MetaCyc:1.14.18.2-RXN
xref: RHEA:16145
is_a: GO:0016716 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.18.2
+property_value: skos:exactMatch RHEA:16145
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25976" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030339
@@ -165217,14 +171650,16 @@
xref: MetaCyc:FATTY-ACYL-ETHYL-ESTER-SYNTHASE-RXN
xref: RHEA:16641
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.67
+property_value: skos:exactMatch RHEA:16641
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030340
name: hyaluronate lyase activity
namespace: molecular_function
-def: "Catalysis of the reaction: hyaluronate = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine." [EC:4.2.2.1]
+def: "Catalysis of the reaction: hyaluronate(n) = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine + H2O." [RHEA:50240]
synonym: "glucuronoglycosaminoglycan lyase activity" RELATED [EC:4.2.2.1]
-synonym: "hyaluronidase [but cf. EC:3.2.1.35 (hyalurononglucosaminidase) and EC:3.2.1.36 (hyaluronoglucuronidase)]" RELATED [EC:4.2.2.1]
synonym: "hyaluronidase activity" BROAD [EC:4.2.2.1]
synonym: "mucinase activity" RELATED [EC:4.2.2.1]
synonym: "spreading factor activity" RELATED [EC:4.2.2.1]
@@ -165232,6 +171667,9 @@
xref: MetaCyc:HYALURONATE-LYASE-RXN
xref: RHEA:50240
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.1
+property_value: skos:exactMatch RHEA:50240
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31195" xsd:anyURI
[Term]
id: GO:0030341
@@ -165246,7 +171684,10 @@
synonym: "chondroitinase activity" BROAD []
xref: EC:4.2.2.5
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:broadMatch MetaCyc:4.2.2.5-RXN
+property_value: skos:exactMatch EC:4.2.2.5
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030342
@@ -165260,7 +171701,9 @@
xref: Reactome:R-HSA-5602004 "Defective CYP24A1 does not 24-hydroxylate CALTOL"
xref: RHEA:24964
is_a: GO:0070576 ! vitamin D 24-hydroxylase activity
+property_value: skos:exactMatch RHEA:24964
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28340" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030343
@@ -165274,6 +171717,7 @@
xref: RHEA:32903
is_a: GO:0008395 ! steroid hydroxylase activity
relationship: part_of GO:0036378 ! calcitriol biosynthetic process from calciol
+property_value: skos:exactMatch RHEA:32903
[Term]
id: GO:0030345
@@ -165314,6 +171758,8 @@
xref: Reactome:R-HSA-1855163 "I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen"
xref: RHEA:77143
is_a: GO:0052827 ! inositol pentakisphosphate phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.62
+property_value: skos:exactMatch RHEA:77143
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25949" xsd:anyURI
[Term]
@@ -165323,6 +171769,8 @@
def: "Catalysis of the reaction: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate." [RHEA:77147]
xref: RHEA:77147
is_a: GO:0052743 ! inositol tetrakisphosphate phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.62
+property_value: skos:exactMatch RHEA:77147
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25949" xsd:anyURI
[Term]
@@ -165407,6 +171855,9 @@
xref: Reactome:R-HSA-947541 "Sulfhydrylation and ring cleavage of precursor Z"
xref: RHEA:26333
is_a: GO:0016783 ! sulfurtransferase activity
+property_value: skos:exactMatch EC:2.8.1.12
+property_value: skos:exactMatch RHEA:26333
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030367
@@ -165529,6 +171980,9 @@
xref: Reactome:R-HSA-9014766 "PXLP-K56-SRR dimer isomerises L-Ser to D-Ser"
xref: RHEA:10980
is_a: GO:0047661 ! amino-acid racemase activity
+property_value: skos:exactMatch EC:5.1.1.18
+property_value: skos:exactMatch RHEA:10980
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030379
@@ -165790,6 +172244,9 @@
xref: MetaCyc:GLYCINE-FORMIMINOTRANSFERASE-RXN
xref: RHEA:24288
is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity
+property_value: skos:exactMatch EC:2.1.2.4
+property_value: skos:exactMatch RHEA:24288
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030409
@@ -165808,7 +172265,10 @@
xref: MetaCyc:GLUTAMATE-FORMIMINOTRANSFERASE-RXN
xref: RHEA:15097
is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity
+property_value: skos:exactMatch EC:2.1.2.5
+property_value: skos:exactMatch RHEA:15097
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030410
@@ -165821,6 +172281,9 @@
xref: MetaCyc:2.5.1.43-RXN
xref: RHEA:16481
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.43
+property_value: skos:exactMatch RHEA:16481
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030411
@@ -165834,6 +172297,9 @@
xref: MetaCyc:SCYTALONE-DEHYDRATASE-RXN
xref: RHEA:24396
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.94
+property_value: skos:exactMatch RHEA:24396
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030412
@@ -165850,6 +172316,9 @@
xref: Reactome:R-HSA-70920 "N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate"
xref: RHEA:22736
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.4
+property_value: skos:exactMatch RHEA:22736
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030413
@@ -166024,8 +172493,13 @@
synonym: "L-kynurenine hydrolase activity" RELATED [EC:3.7.1.3]
xref: EC:3.7.1.3
xref: MetaCyc:KYNURENINASE-RXN
-xref: Reactome:R-HSA-71217 "3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+"
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+xref: Reactome:R-HSA-71217 "3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine"
+xref: RHEA:16813
+xref: RHEA:25143
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.3
+property_value: skos:narrowMatch RHEA:16813
+property_value: skos:narrowMatch RHEA:25143
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -167323,6 +173797,8 @@
xref: EC:4.2.2.2
xref: MetaCyc:4.2.2.2-RXN
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.2
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030572
@@ -167491,6 +173967,9 @@
xref: MetaCyc:4.1.1.38-RXN
xref: RHEA:22356
is_a: GO:0004611 ! phosphoenolpyruvate carboxykinase activity
+property_value: skos:exactMatch EC:4.1.1.38
+property_value: skos:exactMatch RHEA:22356
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030586
@@ -167506,9 +173985,14 @@
xref: EC:1.16.1.8
xref: MetaCyc:2.1.1.135-RXN
xref: Reactome:R-HSA-3149518 "MTRR reduces cob(II)alamin to meCbl"
+xref: RHEA:20752
xref: RHEA:23908
is_a: GO:0016723 ! oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.16.1.8
+property_value: skos:exactMatch RHEA:23908
+property_value: skos:narrowMatch RHEA:20752
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28557" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030587
@@ -167600,7 +174084,10 @@
xref: MetaCyc:3.2.1.40-RXN
xref: RHEA:17465
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.40
+property_value: skos:exactMatch RHEA:17465
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24927" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030597
@@ -167629,6 +174116,8 @@
xref: MetaCyc:3.2.2.22-RXN
is_a: GO:0030597 ! RNA glycosylase activity
is_a: GO:0140102 ! catalytic activity, acting on a rRNA
+property_value: skos:exactMatch EC:3.2.2.22
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030599
@@ -167646,6 +174135,9 @@
xref: MetaCyc:RXN-19782
xref: RHEA:22380
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.11
+property_value: skos:exactMatch RHEA:22380
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030600
@@ -167665,6 +174157,8 @@
xref: EC:3.1.1.73
xref: MetaCyc:3.1.1.73-RXN
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.73
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030601
@@ -167704,7 +174198,10 @@
xref: KEGG_REACTION:R00338
xref: MetaCyc:OXALOACETASE-RXN
xref: RHEA:24432
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.1
+property_value: skos:exactMatch RHEA:24432
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030604
@@ -167722,6 +174219,9 @@
xref: MetaCyc:DXPREDISOM-RXN
xref: RHEA:13717
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.267
+property_value: skos:exactMatch RHEA:13717
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030611
@@ -167736,7 +174236,10 @@
xref: MetaCyc:1.20.99.1-RXN
xref: RHEA:18449
is_a: GO:0030613 ! oxidoreductase activity, acting on phosphorus or arsenic in donors
+property_value: skos:exactMatch EC:1.20.99.1
+property_value: skos:exactMatch RHEA:18449
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030612
@@ -167747,6 +174250,8 @@
xref: MetaCyc:RXN-10737
xref: RHEA:43848
is_a: GO:0030614 ! oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor
+property_value: skos:exactMatch EC:1.20.4.4
+property_value: skos:exactMatch RHEA:43848
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
[Term]
@@ -167757,6 +174262,8 @@
synonym: "oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors" NARROW []
xref: EC:1.20.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.20.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030614
@@ -167766,6 +174273,8 @@
synonym: "oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulphide as acceptor" EXACT []
xref: EC:1.20.4.-
is_a: GO:0030613 ! oxidoreductase activity, acting on phosphorus or arsenic in donors
+property_value: skos:exactMatch EC:1.20.4.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030616
@@ -168057,14 +174566,16 @@
[Term]
id: GO:0030645
-name: glucose catabolic process to butyrate
+name: acetyl-CoA fermentation to butanoate
namespace: biological_process
-def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum." [ISBN:0198506732]
+def: "The anaerobic chemical reactions and pathways resulting in the production of acetic acid, butyric acid, and dihydrogen from acetyl-CoA; effected by some saccharolytic species of Clostridium, e.g. C. butyricum." [ISBN:0198506732, Metacyc:PWY-5676]
synonym: "butyrate fermentation" EXACT []
-synonym: "glucose fermentation to butyrate" EXACT []
-is_a: GO:0006007 ! glucose catabolic process
-is_a: GO:0006113 ! fermentation
+synonym: "glucose catabolic process to butyrate" RELATED []
+synonym: "glucose fermentation to butyrate" RELATED []
+xref: Metacyc:PWY-5676
is_a: GO:0019605 ! butyrate metabolic process
+is_a: GO:0046356 ! acetyl-CoA catabolic process
+relationship: part_of GO:0006113 ! fermentation
[Term]
id: GO:0030647
@@ -168120,7 +174631,6 @@
synonym: "peptide antibiotic synthesis" EXACT []
is_a: GO:0017000 ! antibiotic biosynthetic process
is_a: GO:0043043 ! peptide biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
[Term]
id: GO:0030652
@@ -168132,7 +174642,6 @@
synonym: "peptide antibiotic degradation" EXACT []
is_a: GO:0017001 ! antibiotic catabolic process
is_a: GO:0043171 ! peptide catabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0030653
@@ -168342,12 +174851,6 @@
synonym: "protein recruiting activity" RELATED []
synonym: "protein-containing complex scaffold activity" BROAD []
synonym: "protein-protein adaptor" NARROW []
-xref: Reactome:R-HSA-3780997 "PPP1R3C binds to glycogen:GYG2:GYS2"
-xref: Reactome:R-HSA-3781001 "EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex"
-xref: Reactome:R-HSA-3781021 "EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG2 complex"
-xref: Reactome:R-HSA-3781023 "PPP1R3C binds to glycogen:GYG1:GYS1"
-xref: Reactome:R-HSA-8871366 "p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP"
-xref: Reactome:R-HSA-8871376 "p-Y389,400-RUFY1 binds PI3P"
is_a: GO:0060090 ! molecular adaptor activity
relationship: has_part GO:0005515 ! protein binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18655" xsd:anyURI
@@ -168597,7 +175100,10 @@
xref: RHEA:42712
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
is_a: GO:0016300 ! tRNA (uridine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.35
+property_value: skos:exactMatch RHEA:42712
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26118" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030698
@@ -168621,6 +175127,9 @@
xref: MetaCyc:RXN-7566
xref: RHEA:12232
is_a: GO:0050485 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor
+property_value: skos:exactMatch EC:1.21.4.2
+property_value: skos:exactMatch RHEA:12232
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030700
@@ -168645,6 +175154,9 @@
xref: MetaCyc:2.4.2.37-RXN
xref: RHEA:18077
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.37
+property_value: skos:exactMatch RHEA:18077
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030703
@@ -168914,6 +175426,9 @@
xref: RHEA:16117
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.16
+property_value: skos:exactMatch RHEA:16117
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030730
@@ -168954,6 +175469,9 @@
xref: MetaCyc:GUANIDINOACETATE-N-METHYLTRANSFERASE-RXN
xref: RHEA:10656
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.2
+property_value: skos:exactMatch RHEA:10656
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030732
@@ -168969,6 +175487,9 @@
xref: MetaCyc:METHIONINE-S-METHYLTRANSFERASE-RXN
xref: RHEA:13761
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.12
+property_value: skos:exactMatch RHEA:13761
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030733
@@ -168982,6 +175503,9 @@
xref: MetaCyc:FATTY-ACID-O-METHYLTRANSFERASE-RXN
xref: RHEA:23012
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.15
+property_value: skos:exactMatch RHEA:23012
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030734
@@ -168994,6 +175518,8 @@
xref: EC:2.1.1.18
xref: MetaCyc:POLYSACCHARIDE-O-METHYLTRANSFERASE-RXN
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.18
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030735
@@ -169007,6 +175533,9 @@
xref: Reactome:R-HSA-8876789 "CARNMT1 methylates CARN to Anserine"
xref: RHEA:14205
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.22
+property_value: skos:exactMatch RHEA:14205
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030736
@@ -169020,6 +175549,9 @@
xref: MetaCyc:PHENOL-O-METHYLTRANSFERASE-RXN
xref: RHEA:14809
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.25
+property_value: skos:exactMatch RHEA:14809
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030737
@@ -169032,6 +175564,9 @@
xref: MetaCyc:IODOPHENOL-O-METHYLTRANSFERASE-RXN
xref: RHEA:14313
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.26
+property_value: skos:exactMatch RHEA:14313
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030738
@@ -169047,6 +175582,9 @@
xref: MetaCyc:TYRAMINE-N-METHYLTRANSFERASE-RXN
xref: RHEA:14865
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.27
+property_value: skos:exactMatch RHEA:14865
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030739
@@ -169059,6 +175597,9 @@
xref: MetaCyc:2.1.1.38-RXN
xref: RHEA:22280
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.38
+property_value: skos:exactMatch RHEA:22280
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030740
@@ -169077,6 +175618,9 @@
xref: MetaCyc:MYO-INOSITOL-1-O-METHYLTRANSFERASE-RXN
xref: RHEA:18877
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.39
+property_value: skos:exactMatch RHEA:18877
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030741
@@ -169095,6 +175639,9 @@
xref: MetaCyc:MYO-INOSITOL-3-O-METHYLTRANSFERASE-RXN
xref: RHEA:17565
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.40
+property_value: skos:exactMatch RHEA:17565
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030742
@@ -169119,7 +175666,10 @@
xref: RHEA:43212
is_a: GO:0016433 ! rRNA (adenine) methyltransferase activity
is_a: GO:0062105 ! RNA 2'-O-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.230
+property_value: skos:exactMatch RHEA:43212
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25985" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030744
@@ -169154,6 +175704,9 @@
xref: MetaCyc:ISOFLAVONE-4-O-METHYLTRANSFERASE-RXN
xref: RHEA:31739
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.46
+property_value: skos:exactMatch RHEA:31739
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030747
@@ -169169,7 +175722,10 @@
xref: MetaCyc:RXN-17530
xref: RHEA:12112
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.47
+property_value: skos:exactMatch RHEA:12112
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25985" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030748
@@ -169183,8 +175739,16 @@
synonym: "tryptamine N-methyltransferase activity" NARROW [EC:2.1.1.49]
xref: EC:2.1.1.49
xref: MetaCyc:AMINE-N-METHYLTRANSFERASE-RXN
+xref: RHEA:23136
+xref: RHEA:53924
+xref: RHEA:53928
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.49
+property_value: skos:narrowMatch RHEA:23136
+property_value: skos:narrowMatch RHEA:53924
+property_value: skos:narrowMatch RHEA:53928
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030749
@@ -169198,6 +175762,9 @@
xref: MetaCyc:LOGANATE-O-METHYLTRANSFERASE-RXN
xref: RHEA:12508
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.50
+property_value: skos:exactMatch RHEA:12508
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030750
@@ -169211,6 +175778,9 @@
xref: MetaCyc:PUTRESCINE-N-METHYLTRANSFERASE-RXN
xref: RHEA:15037
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.53
+property_value: skos:exactMatch RHEA:15037
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030751
@@ -169223,6 +175793,9 @@
xref: MetaCyc:LICODIONE-2-O-METHYLTRANSFERASE-RXN
xref: RHEA:18521
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.65
+property_value: skos:exactMatch RHEA:18521
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030752
@@ -169244,7 +175817,10 @@
xref: MetaCyc:RXN-8448
xref: RHEA:18861
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.69
+property_value: skos:exactMatch RHEA:18861
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30155" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030753
@@ -169264,6 +175840,8 @@
xref: EC:2.1.1.70
xref: KEGG_REACTION:R02982
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.70
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030754
@@ -169277,6 +175855,9 @@
xref: MetaCyc:APIGENIN-4-O-METHYLTRANSFERASE-RXN
xref: RHEA:20429
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.75
+property_value: skos:exactMatch RHEA:20429
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030755
@@ -169290,6 +175871,9 @@
xref: MetaCyc:QUERCETIN-3-O-METHYLTRANSFERASE-RXN
xref: RHEA:17673
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.76
+property_value: skos:exactMatch RHEA:17673
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030756
@@ -169303,6 +175887,9 @@
xref: MetaCyc:ISOORIENTIN-3-O-METHYLTRANSFERASE-RXN
xref: RHEA:24096
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.78
+property_value: skos:exactMatch RHEA:24096
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030757
@@ -169320,6 +175907,9 @@
xref: MetaCyc:2.1.1.82-RXN
xref: RHEA:16181
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.82
+property_value: skos:exactMatch RHEA:16181
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030758
@@ -169337,6 +175927,9 @@
xref: MetaCyc:2.1.1.83-RXN
xref: RHEA:21832
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.83
+property_value: skos:exactMatch RHEA:21832
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030759
@@ -169352,6 +175945,9 @@
xref: MetaCyc:2.1.1.84-RXN
xref: RHEA:18717
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.84
+property_value: skos:exactMatch RHEA:18717
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030760
@@ -169366,6 +175962,9 @@
xref: Reactome:R-HSA-175987 "NNMT transfers CH3 from AdoMet to PY"
xref: RHEA:16893
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.87
+property_value: skos:exactMatch RHEA:16893
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030761
@@ -169381,6 +175980,9 @@
xref: MetaCyc:2.1.1.88-RXN
xref: RHEA:16593
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.88
+property_value: skos:exactMatch RHEA:16593
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030762
@@ -169394,6 +175996,9 @@
xref: MetaCyc:2.1.1.89-RXN
xref: RHEA:22536
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.89
+property_value: skos:exactMatch RHEA:22536
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030763
@@ -169409,6 +176014,9 @@
xref: MetaCyc:ISOBUTYRALDOXIME-O-METHYLTRANSFERASE-RXN
xref: RHEA:10996
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.91
+property_value: skos:exactMatch RHEA:10996
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030766
@@ -169423,6 +176031,9 @@
xref: MetaCyc:2.1.1.94-RXN
xref: RHEA:20992
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.94
+property_value: skos:exactMatch RHEA:20992
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030767
@@ -169436,6 +176047,9 @@
xref: MetaCyc:2.1.1.97-RXN
xref: RHEA:17833
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.97
+property_value: skos:exactMatch RHEA:17833
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030768
@@ -169452,6 +176066,9 @@
xref: MetaCyc:2.1.1.99-RXN
xref: RHEA:11336
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.99
+property_value: skos:exactMatch RHEA:11336
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030769
@@ -169466,6 +176083,9 @@
xref: MetaCyc:MACROCIN-O-METHYLTRANSFERASE-RXN
xref: RHEA:17269
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.101
+property_value: skos:exactMatch RHEA:17269
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030770
@@ -169479,6 +176099,9 @@
xref: MetaCyc:DEMETHYLMACROCIN-O-METHYLTRANSFERASE-RXN
xref: RHEA:17573
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.102
+property_value: skos:exactMatch RHEA:17573
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030771
@@ -169493,6 +176116,9 @@
xref: MetaCyc:2.1.1.105-RXN
xref: RHEA:17405
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.105
+property_value: skos:exactMatch RHEA:17405
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030772
@@ -169507,6 +176133,9 @@
xref: MetaCyc:RXN-16751
xref: RHEA:17321
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.106
+property_value: skos:exactMatch RHEA:17321
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030773
@@ -169520,6 +176149,9 @@
xref: MetaCyc:6-HYDROXYMELLEIN-O-METHYLTRANSFERASE-RXN
xref: RHEA:15201
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.108
+property_value: skos:exactMatch RHEA:15201
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030774
@@ -169533,6 +176165,9 @@
xref: MetaCyc:ANTHRANILATE-N-METHYLTRANSFERASE-RXN
xref: RHEA:12180
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.111
+property_value: skos:exactMatch RHEA:12180
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030775
@@ -169544,6 +176179,9 @@
xref: MetaCyc:GLUCURONOXYLAN-4-O-METHYLTRANSFERASE-RXN
xref: RHEA:20413
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.112
+property_value: skos:exactMatch RHEA:20413
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030776
@@ -169557,6 +176195,9 @@
xref: MetaCyc:2.1.1.115-RXN
xref: RHEA:13005
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.115
+property_value: skos:exactMatch RHEA:13005
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030777
@@ -169570,6 +176211,9 @@
xref: MetaCyc:2.1.1.117-RXN
xref: RHEA:23808
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.117
+property_value: skos:exactMatch RHEA:23808
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030778
@@ -169582,6 +176226,9 @@
xref: MetaCyc:2.1.1.118-RXN
xref: RHEA:15373
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.118
+property_value: skos:exactMatch RHEA:15373
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030779
@@ -169594,6 +176241,9 @@
xref: MetaCyc:2.1.1.119-RXN
xref: RHEA:18541
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.119
+property_value: skos:exactMatch RHEA:18541
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030780
@@ -169606,6 +176256,9 @@
xref: MetaCyc:2.1.1.120-RXN
xref: RHEA:21092
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.120
+property_value: skos:exactMatch RHEA:21092
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030781
@@ -169617,6 +176270,9 @@
xref: MetaCyc:2.1.1.121-RXN
xref: RHEA:11892
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.121
+property_value: skos:exactMatch RHEA:11892
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030782
@@ -169629,7 +176285,10 @@
xref: MetaCyc:RXN-23969
xref: RHEA:76067
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.122
+property_value: skos:exactMatch RHEA:76067
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30156" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030783
@@ -169641,6 +176300,8 @@
xref: EC:2.1.1.123
xref: MetaCyc:2.1.1.123-RXN
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.123
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030784
@@ -169652,6 +176313,9 @@
xref: MetaCyc:2.1.1.116-RXN
xref: RHEA:17789
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.116
+property_value: skos:exactMatch RHEA:17789
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030785
@@ -169669,6 +176333,9 @@
xref: MetaCyc:2.1.1.127-RXN
xref: RHEA:50996
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.127
+property_value: skos:exactMatch RHEA:50996
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030786
@@ -169680,6 +176347,9 @@
xref: MetaCyc:2.1.1.128-RXN
xref: RHEA:19941
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.128
+property_value: skos:exactMatch RHEA:19941
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030787
@@ -169695,6 +176365,9 @@
xref: MetaCyc:2.1.1.129-RXN
xref: RHEA:23248
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.129
+property_value: skos:exactMatch RHEA:23248
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030788
@@ -169708,6 +176381,9 @@
xref: MetaCyc:2.1.1.130-RXN
xref: RHEA:16841
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.130
+property_value: skos:exactMatch RHEA:16841
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030789
@@ -169722,6 +176398,9 @@
xref: MetaCyc:2.1.1.131-RXN
xref: RHEA:12761
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.131
+property_value: skos:exactMatch RHEA:12761
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030790
@@ -169735,6 +176414,9 @@
xref: MetaCyc:2.1.1.136-RXN
xref: RHEA:18909
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.136
+property_value: skos:exactMatch RHEA:18909
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030791
@@ -169746,10 +176428,23 @@
synonym: "S-adenosyl-L-methionine:arsenite As-methyltransferase activity" RELATED [EC:2.1.1.137]
synonym: "S-adenosyl-L-methionine:methylarsonite As-methyltransferase activity" RELATED [EC:2.1.1.137]
xref: EC:2.1.1.137
+xref: MetaCyc:2.1.1.137-RXN
+xref: MetaCyc:RXN-21028
+xref: MetaCyc:RXN-22330
xref: Reactome:R-HSA-5696213 "AS3MT transfers CH3 from AdoMet to methylarsonite"
xref: Reactome:R-HSA-5696220 "AS3MT transfers CH3 from AdoMet to arsenite(3-)"
+xref: RHEA:69432
+xref: RHEA:69460
+xref: RHEA:69464
xref: UM-BBD_reactionID:r0805
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.137
+property_value: skos:narrowMatch MetaCyc:2.1.1.137-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-21028
+property_value: skos:narrowMatch MetaCyc:RXN-22330
+property_value: skos:narrowMatch RHEA:69432
+property_value: skos:narrowMatch RHEA:69460
+property_value: skos:narrowMatch RHEA:69464
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23472" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -169777,6 +176472,9 @@
xref: MetaCyc:2.1.1.139-RXN
xref: RHEA:11696
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.139
+property_value: skos:exactMatch RHEA:11696
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030794
@@ -169788,6 +176486,9 @@
xref: MetaCyc:2.1.1.140-RXN
xref: RHEA:17409
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.140
+property_value: skos:exactMatch RHEA:17409
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030795
@@ -169803,6 +176504,9 @@
xref: MetaCyc:RXN-10768
xref: RHEA:13349
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.141
+property_value: skos:exactMatch RHEA:13349
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030796
@@ -169816,6 +176520,9 @@
xref: MetaCyc:2.1.1.142-RXN
xref: RHEA:13137
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.142
+property_value: skos:exactMatch RHEA:13137
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030797
@@ -169832,6 +176539,9 @@
xref: MetaCyc:2.1.1.143-RXN
xref: RHEA:21044
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.143
+property_value: skos:exactMatch RHEA:21044
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030798
@@ -169844,6 +176554,9 @@
xref: MetaCyc:RXN0-2441
xref: RHEA:14969
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.144
+property_value: skos:exactMatch RHEA:14969
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030799
@@ -170671,6 +177384,9 @@
xref: MetaCyc:4.3.1.16-RXN
xref: RHEA:12424
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.16
+property_value: skos:exactMatch RHEA:12424
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0030849
@@ -171603,6 +178319,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. This reaction requires metal ions." [GOC:mah]
is_a: GO:0004725 ! protein tyrosine phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.48
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -172903,6 +179620,9 @@
xref: Reactome:R-HSA-947514 "PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3"
xref: RHEA:43892
is_a: GO:0016783 ! sulfurtransferase activity
+property_value: skos:exactMatch EC:2.8.1.7
+property_value: skos:exactMatch RHEA:43892
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031072
@@ -172919,6 +179639,7 @@
xref: RHEA:43836
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016716 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:43836
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29029" xsd:anyURI
[Term]
@@ -172960,6 +179681,7 @@
synonym: "histone H3K14 deacetylase activity" BROAD []
is_a: GO:0141050 ! histone H3K deacetylase activity
is_a: GO:0141221 ! histone deacetylase activity, hydrolytic mechanism
+property_value: skos:broadMatch EC:3.5.1.98
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
[Term]
@@ -173518,6 +180240,9 @@
xref: RHEA:21596
xref: Wikipedia:Serine_3-dehydrogenase
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.276
+property_value: skos:exactMatch RHEA:21596
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031133
@@ -173949,7 +180674,6 @@
synonym: "ferrichrome formation" EXACT []
synonym: "ferrichrome synthesis" EXACT []
is_a: GO:0019539 ! hydroxymate-containing siderophore biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
[Term]
id: GO:0031170
@@ -173985,6 +180709,8 @@
xref: MetaCyc:RXN-11128
xref: RHEA:41508
is_a: GO:0004497 ! monooxygenase activity
+property_value: skos:exactMatch RHEA:41508
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031173
@@ -174037,6 +180763,8 @@
xref: EC:3.2.1.8
xref: MetaCyc:3.2.1.8-RXN
is_a: GO:0097599 ! xylanase activity
+property_value: skos:exactMatch EC:3.2.1.8
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031177
@@ -174044,7 +180772,6 @@
namespace: molecular_function
def: "Binding to phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate)." [GOC:mah, GOC:vw]
is_a: GO:0019842 ! vitamin binding
-is_a: GO:0033218 ! amide binding
is_a: GO:0072341 ! modified amino acid binding
[Term]
@@ -174132,8 +180859,6 @@
name: phosphatidylcholine binding
namespace: molecular_function
def: "Binding to a phosphatidylcholine, a glycophospholipid in which a phosphatidyl group is esterified to the hydroxyl group of choline." [GOC:mah, ISBN:0198506732]
-xref: Reactome:R-HSA-8873794 "PCTP binds PC"
-xref: Reactome:R-HSA-8873923 "STARD10 binds LPCAT1 and PC"
is_a: GO:0005543 ! phospholipid binding
is_a: GO:0043169 ! cation binding
is_a: GO:0050997 ! quaternary ammonium group binding
@@ -174180,6 +180905,8 @@
xref: EC:3.2.1.135
xref: MetaCyc:3.2.1.135-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.135
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031217
@@ -174198,6 +180925,8 @@
xref: EC:3.2.1.74
xref: MetaCyc:3.2.1.74-RXN
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.74
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031218
@@ -174211,6 +180940,8 @@
xref: EC:3.2.1.89
xref: MetaCyc:3.2.1.89-RXN
is_a: GO:0015925 ! galactosidase activity
+property_value: skos:exactMatch EC:3.2.1.89
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031219
@@ -174222,6 +180953,8 @@
xref: EC:3.2.1.65
xref: MetaCyc:3.2.1.65-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.65
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031220
@@ -174231,6 +180964,9 @@
xref: MetaCyc:RXN0-5182
xref: RHEA:29691
is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity
+property_value: skos:broadMatch EC:2.4.1.1
+property_value: skos:exactMatch MetaCyc:RXN0-5182
+property_value: skos:exactMatch RHEA:29691
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -175122,6 +181858,9 @@
xref: MetaCyc:TAURINE-AMINOTRANSFERASE-RXN
xref: RHEA:10420
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.77
+property_value: skos:exactMatch RHEA:10420
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031300
@@ -176975,7 +183714,9 @@
is_a: GO:0015199 ! amino-acid betaine transmembrane transporter activity
is_a: GO:0015418 ! ABC-type quaternary ammonium compound transporting activity
relationship: part_of GO:0031460 ! glycine betaine transport
+property_value: skos:exactMatch RHEA:32783
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031460
@@ -177894,6 +184635,8 @@
xref: Reactome:R-HSA-1234181 "Nuclear PHD1,3 hydroxylates proline residues on HIF1A"
xref: RHEA:63484
is_a: GO:0031543 ! peptidyl-proline dioxygenase activity
+property_value: skos:exactMatch RHEA:63484
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031546
@@ -178716,7 +185459,7 @@
name: beta-endorphin binding
namespace: molecular_function
def: "Binding to beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin." [GOC:nln, PMID:6267560]
-is_a: GO:0033218 ! amide binding
+is_a: GO:0005488 ! binding
[Term]
id: GO:0031627
@@ -178864,6 +185607,7 @@
name: killing of cells of another organism
namespace: biological_process
alt_id: GO:0001908
+alt_id: GO:0051852
def: "Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions." [GOC:add]
subset: goslim_pir
synonym: "killing of cells of other organism" EXACT []
@@ -181724,9 +188468,11 @@
synonym: "short-chain-fatty-acid-CoA ligase activity" EXACT []
xref: RHEA:52860
is_a: GO:0120515 ! fatty acid-CoA ligase activity
+property_value: skos:exactMatch RHEA:52860
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23296" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26439" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031956
@@ -181741,10 +188487,13 @@
xref: Reactome:R-HSA-8875013 "ACSM3,ACSM6 ligate CoA to BUT"
xref: RHEA:48340
is_a: GO:0120515 ! fatty acid-CoA ligase activity
+property_value: skos:exactMatch EC:6.2.1.2
+property_value: skos:exactMatch RHEA:48340
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14783" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18967" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23497" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031957
@@ -181761,8 +188510,10 @@
xref: Reactome:R-HSA-9914143 "SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH"
xref: RHEA:54536
is_a: GO:0120515 ! fatty acid-CoA ligase activity
+property_value: skos:exactMatch RHEA:54536
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26439" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0031958
@@ -181827,6 +188578,7 @@
synonym: "carcinine hydrolase activity" EXACT []
xref: RHEA:73463
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch RHEA:73463
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29728" xsd:anyURI
[Term]
@@ -182175,6 +188927,8 @@
xref: EC:2.4.1.24
xref: MetaCyc:2.4.1.24-RXN
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.24
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0032002
@@ -182375,6 +189129,7 @@
synonym: "2-methylbutyraldehyde reductase (NADP) activity" EXACT []
xref: RHEA:84375
is_a: GO:0008106 ! alcohol dehydrogenase (NADP+) activity
+property_value: skos:exactMatch RHEA:84375
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29946" xsd:anyURI
[Term]
@@ -182565,6 +189320,7 @@
synonym: "NAD-dependent histone H3K14 deacetylase activity" EXACT []
is_a: GO:0017136 ! histone deacetylase activity, NAD-dependent
is_a: GO:0141050 ! histone H3K deacetylase activity
+property_value: skos:broadMatch EC:2.3.1.286
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22836" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -182679,7 +189435,6 @@
name: bile acid binding
namespace: molecular_function
def: "Binding to a bile acid, a steroid carboxylic acids occurring in bile." [GOC:rph]
-xref: Reactome:R-HSA-8873850 "STARD5 binds DCA, LCA"
is_a: GO:0033293 ! monocarboxylic acid binding
[Term]
@@ -183136,13 +189891,14 @@
[Term]
id: GO:0032088
-name: negative regulation of NF-kappaB transcription factor activity
+name: obsolete negative regulation of NF-kappaB transcription factor activity
namespace: biological_process
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB." [GOC:dph, GOC:rl, GOC:tb]
-subset: gocheck_obsoletion_candidate
+def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB." [GOC:dph, GOC:rl, GOC:tb]
+comment: The reason for obsoletion is that this term represents a molecular function.
synonym: "inhibition of NF-kappaB transcription factor" EXACT [GOC:dph, GOC:tb]
synonym: "NF-kappaB inhibitor" RELATED []
-is_a: GO:0043433 ! negative regulation of DNA-binding transcription factor activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30856" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0032089
@@ -183479,6 +190235,9 @@
xref: MetaCyc:1.1.1.289-RXN
xref: RHEA:14609
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.289
+property_value: skos:exactMatch RHEA:14609
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0032116
@@ -183620,6 +190379,7 @@
synonym: "histone H3K9 deacetylase activity" BROAD []
is_a: GO:0141050 ! histone H3K deacetylase activity
is_a: GO:0141221 ! histone deacetylase activity, hydrolytic mechanism
+property_value: skos:broadMatch EC:3.5.1.98
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
[Term]
@@ -184482,6 +191242,7 @@
synonym: "GPI-inositol acyltransferase" RELATED []
xref: RHEA:60496
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch RHEA:60496
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30693" xsd:anyURI
[Term]
@@ -184506,14 +191267,15 @@
[Term]
id: GO:0032219
-name: cell wall macromolecule catabolic process involved in cytogamy
+name: obsolete cell wall macromolecule catabolic process involved in cytogamy
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy." [GOC:mah]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy." [GOC:mah]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "cell wall macromolecule catabolic process during cytogamy" RELATED [GOC:dph, GOC:tb]
-is_a: GO:0016998 ! cell wall macromolecule catabolic process
-intersection_of: GO:0016998 ! cell wall macromolecule catabolic process
-intersection_of: part_of GO:0000755 ! cytogamy
-relationship: part_of GO:0000755 ! cytogamy
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0000755
+consider: GO:0016998
[Term]
id: GO:0032220
@@ -185083,7 +191845,6 @@
def: "Binding to phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position." [GOC:bf, PMID:10209156, PMID:11395417, PMID:11557775]
synonym: "phosphatidylinositol 3-phosphate binding" EXACT []
synonym: "PtdIns-3-P binding" EXACT []
-xref: Reactome:R-HSA-8870489 "PLEKHA4,(5,6) bind PI3P"
is_a: GO:1901981 ! phosphatidylinositol phosphate binding
[Term]
@@ -185097,7 +191858,10 @@
xref: RHEA:43744
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:6.3.4.19
+property_value: skos:exactMatch RHEA:43744
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28066" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0032271
@@ -186844,7 +193608,9 @@
xref: EC:3.2.1.53
xref: MetaCyc:3.2.1.53-RXN
is_a: GO:0004563 ! beta-N-acetylhexosaminidase activity
+property_value: skos:exactMatch EC:3.2.1.53
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0032429
@@ -186852,7 +193618,7 @@
namespace: biological_process
def: "OBSOLETE. Any process that modulates the activity of the enzyme phospholipase A2." [GOC:mah]
comment: This term was obsoleted because it represents a molecular function.
-property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22455" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28033" xsd:anyURI
is_obsolete: true
[Term]
@@ -186866,7 +193632,7 @@
synonym: "up regulation of phospholipase A2 activity" EXACT []
synonym: "up-regulation of phospholipase A2 activity" EXACT []
synonym: "upregulation of phospholipase A2 activity" EXACT []
-property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22455" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28033" xsd:anyURI
is_obsolete: true
[Term]
@@ -186969,9 +193735,13 @@
synonym: "n-alkanal:NAD(P)+ 2-oxidoreductase activity" RELATED [EC:1.3.1.74]
synonym: "NAD(P)H-dependent alkenal/one oxidoreductase activity" RELATED [EC:1.3.1.74]
xref: EC:1.3.1.74
+xref: RHEA:36731
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.74
+property_value: skos:narrowMatch RHEA:36731
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0032441
@@ -186982,6 +193752,9 @@
xref: MetaCyc:RXN-7740
xref: RHEA:48140
is_a: GO:0016730 ! oxidoreductase activity, acting on iron-sulfur proteins as donors
+property_value: skos:exactMatch EC:1.14.15.17
+property_value: skos:exactMatch RHEA:48140
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0032442
@@ -187634,7 +194407,6 @@
name: muramyl dipeptide binding
namespace: molecular_function
def: "Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan." [GOC:rl]
-is_a: GO:0033218 ! amide binding
is_a: GO:0033293 ! monocarboxylic acid binding
is_a: GO:0097367 ! carbohydrate derivative binding
@@ -188049,6 +194821,9 @@
xref: RHEA:17545
is_a: GO:0016209 ! antioxidant activity
is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors
+property_value: skos:exactMatch EC:1.8.98.2
+property_value: skos:exactMatch RHEA:17545
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0032543
@@ -188313,6 +195088,7 @@
xref: Reactome:R-HSA-9682695 "nsp13 helicase melts secondary structures in SARS-CoV-1 genomic RNA template"
xref: Reactome:R-HSA-9694265 "nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template"
is_a: GO:0003724 ! RNA helicase activity
+property_value: skos:exactMatch EC:5.6.2.5
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21612" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -191556,7 +198332,9 @@
is_a: GO:0015087 ! cobalt ion transmembrane transporter activity
is_a: GO:0015662 ! P-type ion transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
+property_value: skos:exactMatch RHEA:32779
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0032780
@@ -191714,29 +198492,30 @@
name: lead ion binding
namespace: molecular_function
def: "Binding to lead (Pb) ions." [GOC:mah]
-xref: Reactome:R-HSA-190141 "ALAD binds to Pb2+"
is_a: GO:0046872 ! metal ion binding
[Term]
id: GO:0032792
-name: negative regulation of CREB transcription factor activity
+name: obsolete negative regulation of CREB transcription factor activity
namespace: biological_process
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB." [GOC:dph, GOC:ecd, GOC:tb]
-subset: gocheck_obsoletion_candidate
+def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB." [GOC:dph, GOC:ecd, GOC:tb]
+comment: The reason for obsoletion is that this term represents a molecular function.
synonym: "CREB inhibitor" RELATED []
synonym: "inhibition of CREB transcription factor" EXACT [GOC:dph, GOC:tb]
-is_a: GO:0043433 ! negative regulation of DNA-binding transcription factor activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30856" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0032793
-name: positive regulation of CREB transcription factor activity
+name: obsolete positive regulation of CREB transcription factor activity
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB." [GOC:dph, GOC:ecd, GOC:tb]
-subset: gocheck_obsoletion_candidate
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB." [GOC:dph, GOC:ecd, GOC:tb]
+comment: The reason for obsoletion is that this term represents a molecular function.
synonym: "activation of CREB" EXACT []
synonym: "activation of CREB transcription factor" EXACT [GOC:dph, GOC:tb]
synonym: "CREB activator" RELATED []
-is_a: GO:0051091 ! positive regulation of DNA-binding transcription factor activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30856" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0032794
@@ -192075,42 +198854,38 @@
[Term]
id: GO:0032820
-name: regulation of natural killer cell proliferation involved in immune response
+name: obsolete regulation of natural killer cell proliferation involved in immune response
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response." [GOC:mah]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response." [GOC:mah]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "regulation of natural killer cell proliferation during immune response" RELATED [GOC:tb]
synonym: "regulation of NK cell proliferation during immune response" RELATED []
-is_a: GO:0002697 ! regulation of immune effector process
-is_a: GO:0032817 ! regulation of natural killer cell proliferation
-is_a: GO:0050776 ! regulation of immune response
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0002324 ! natural killer cell proliferation involved in immune response
-relationship: regulates GO:0002324 ! natural killer cell proliferation involved in immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0032817
[Term]
id: GO:0032821
-name: negative regulation of natural killer cell proliferation involved in immune response
+name: obsolete negative regulation of natural killer cell proliferation involved in immune response
namespace: biological_process
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation as part of an immune response." [GOC:mah]
+def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation as part of an immune response." [GOC:mah]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of natural killer cell proliferation during immune response" RELATED []
synonym: "down-regulation of natural killer cell proliferation during immune response" RELATED []
synonym: "downregulation of natural killer cell proliferation during immune response" RELATED []
synonym: "inhibition of natural killer cell proliferation during immune response" NARROW []
synonym: "negative regulation of natural killer cell proliferation during immune response" RELATED [GOC:tb]
synonym: "negative regulation of NK cell proliferation during immune response" RELATED []
-is_a: GO:0002698 ! negative regulation of immune effector process
-is_a: GO:0032818 ! negative regulation of natural killer cell proliferation
-is_a: GO:0032820 ! regulation of natural killer cell proliferation involved in immune response
-is_a: GO:0050777 ! negative regulation of immune response
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0002324 ! natural killer cell proliferation involved in immune response
-relationship: negatively_regulates GO:0002324 ! natural killer cell proliferation involved in immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0032818
[Term]
id: GO:0032822
-name: positive regulation of natural killer cell proliferation involved in immune response
+name: obsolete positive regulation of natural killer cell proliferation involved in immune response
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation as part of an immune response." [GOC:mah]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation as part of an immune response." [GOC:mah]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of natural killer cell proliferation during immune response" NARROW []
synonym: "positive regulation of natural killer cell proliferation during immune response" RELATED [GOC:tb]
synonym: "positive regulation of NK cell proliferation during immune response" RELATED []
@@ -192118,12 +198893,9 @@
synonym: "up regulation of natural killer cell proliferation during immune response" RELATED []
synonym: "up-regulation of natural killer cell proliferation during immune response" RELATED []
synonym: "upregulation of natural killer cell proliferation during immune response" RELATED []
-is_a: GO:0002699 ! positive regulation of immune effector process
-is_a: GO:0032819 ! positive regulation of natural killer cell proliferation
-is_a: GO:0032820 ! regulation of natural killer cell proliferation involved in immune response
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0002324 ! natural killer cell proliferation involved in immune response
-relationship: positively_regulates GO:0002324 ! natural killer cell proliferation involved in immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0032819
[Term]
id: GO:0032823
@@ -192216,10 +198988,10 @@
[Term]
id: GO:0032828
-name: positive regulation of natural killer cell differentiation involved in immune response
+name: obsolete positive regulation of natural killer cell differentiation involved in immune response
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response." [GOC:mah]
-comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response." [GOC:mah]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of natural killer cell differentiation during immune response" NARROW []
synonym: "positive regulation of natural killer cell development involved in immune response" RELATED [GOC:add]
synonym: "positive regulation of natural killer cell differentiation during immune response" RELATED [GOC:tb]
@@ -192228,13 +199000,9 @@
synonym: "up regulation of natural killer cell differentiation during immune response" RELATED []
synonym: "up-regulation of natural killer cell differentiation during immune response" RELATED []
synonym: "upregulation of natural killer cell differentiation during immune response" RELATED []
-is_a: GO:0002699 ! positive regulation of immune effector process
-is_a: GO:0032825 ! positive regulation of natural killer cell differentiation
-is_a: GO:0032826 ! regulation of natural killer cell differentiation involved in immune response
-is_a: GO:0050778 ! positive regulation of immune response
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0002325 ! natural killer cell differentiation involved in immune response
-relationship: positively_regulates GO:0002325 ! natural killer cell differentiation involved in immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0032825
[Term]
id: GO:0032829
@@ -192315,10 +199083,10 @@
[Term]
id: GO:0032833
-name: negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
+name: obsolete negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
namespace: biological_process
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response." [GOC:mah]
-comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
+def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response." [GOC:mah]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" RELATED []
synonym: "down-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" RELATED []
synonym: "downregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" RELATED []
@@ -192328,13 +199096,9 @@
synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response" RELATED []
synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response" RELATED []
synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response" RELATED []
-is_a: GO:0002698 ! negative regulation of immune effector process
-is_a: GO:0032830 ! negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
-is_a: GO:0032832 ! regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
-is_a: GO:0050777 ! negative regulation of immune response
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0002298 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
-relationship: negatively_regulates GO:0002298 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0032830
[Term]
id: GO:0032834
@@ -192509,14 +199273,19 @@
id: GO:0032866
name: D-xylose reductase (NADPH) activity
namespace: molecular_function
-def: "Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+." [PMID:12724380, PMID:15184173, RHEA:27445]
+def: "Catalysis of the reaction: xylitol + NADP+ = D-xylose + NADPH + H+." [PMID:12724380, PMID:15184173, RHEA:27445]
synonym: "D-xylose reductase activity" BROAD []
synonym: "D-xylose:NADP reductase activity" EXACT []
synonym: "xylose reductase activity" BROAD []
+xref: EC:1.1.1.431
xref: MetaCyc:RXN-8773
xref: RHEA:27445
is_a: GO:0004032 ! aldose reductase (NADPH) activity
+property_value: skos:exactMatch EC:1.1.1.431
+property_value: skos:exactMatch MetaCyc:RXN-8773
+property_value: skos:exactMatch RHEA:27445
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0032867
@@ -192531,7 +199300,9 @@
xref: RHEA:25229
xref: SABIO-RK:1858
is_a: GO:0004032 ! aldose reductase (NADPH) activity
+property_value: skos:exactMatch RHEA:25229
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0032868
@@ -192878,6 +199649,7 @@
synonym: "palmitoyl-CoA delta9-desaturase activity" EXACT []
xref: RHEA:36931
is_a: GO:0016215 ! acyl-CoA desaturase activity
+property_value: skos:exactMatch RHEA:36931
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29820" xsd:anyURI
[Term]
@@ -193331,6 +200103,7 @@
synonym: "histone H3-K56 acetyltransferase activity" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H3-K56 specific)" EXACT []
is_a: GO:0010484 ! histone H3 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -193475,6 +200248,7 @@
synonym: "inositol-tetrakisphosphate 2-kinase activity" BROAD []
xref: MetaCyc:RXN-7182
is_a: GO:0051765 ! inositol tetrakisphosphate kinase activity
+property_value: skos:exactMatch MetaCyc:RXN-7182
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21631" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
@@ -193918,7 +200692,6 @@
xref: Reactome:R-HSA-1307803 "TIMM22 inserts proteins into inner membrane"
xref: Reactome:R-HSA-9902096 "COX18 inserts nascent MT-CO2 in COX20:TMEM77"
xref: Reactome:R-HSA-9906955 "MT-ND4 is translated"
-xref: Reactome:R-HSA-9926981 "Bam complex inserts Hbp into outer membrane"
is_a: GO:0140597 ! protein carrier chaperone
relationship: part_of GO:0090150 ! establishment of protein localization to membrane
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16976" xsd:anyURI
@@ -195177,7 +201950,10 @@
xref: MetaCyc:PUTTRANSAM-RXN
xref: RHEA:12268
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.82
+property_value: skos:exactMatch RHEA:12268
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25992" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033095
@@ -195896,6 +202672,7 @@
xref: EC:2.4.1.232
xref: MetaCyc:2.4.1.232-RXN
is_a: GO:0000009 ! alpha-1,6-mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.232
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30326" xsd:anyURI
[Term]
@@ -196120,6 +202897,9 @@
xref: Reactome:R-HSA-429798 "SGMS1 transfers phosphocholine onto ceramide"
xref: RHEA:18765
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.27
+property_value: skos:exactMatch RHEA:18765
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033189
@@ -196156,6 +202936,7 @@
xref: Reactome:R-HSA-2730849 "Calcineurin binds and dephosphorylates NFAT"
xref: Reactome:R-HSA-4551451 "Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling"
is_a: GO:0004723 ! calcium-dependent protein serine/threonine phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.16
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -196399,18 +203180,19 @@
[Term]
id: GO:0033218
-name: amide binding
+name: obsolete amide binding
namespace: molecular_function
-def: "Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:mah]
-subset: goslim_pir
-is_a: GO:0005488 ! binding
+def: "OBSOLETE. Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:mah]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31123" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0005488
[Term]
id: GO:0033219
name: urea binding
namespace: molecular_function
def: "Binding to urea, a water-soluble carboxamide with the structure H2N-CO-NH2." [GOC:mah, ISBN:0198506732]
-is_a: GO:0033218 ! amide binding
is_a: GO:0036094 ! small molecule binding
[Term]
@@ -196434,6 +203216,8 @@
xref: RHEA:32803
is_a: GO:0015204 ! urea transmembrane transporter activity
is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity
+property_value: skos:exactMatch RHEA:32803
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033222
@@ -196468,6 +203252,8 @@
synonym: "ciliatine transportingATPase activity" EXACT []
xref: RHEA:32775
is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity
+property_value: skos:exactMatch RHEA:32775
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033226
@@ -196523,6 +203309,8 @@
is_a: GO:0015424 ! ABC-type amino acid transporter activity
is_a: GO:0033229 ! cysteine transmembrane transporter activity
is_a: GO:0033284 ! ATPase-coupled carboxylic acid transmembrane transporter activity
+property_value: skos:exactMatch MetaCyc:RXN0-3
+property_value: skos:exactMatch RHEA:29783
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17289" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
@@ -196564,7 +203352,10 @@
is_a: GO:0042943 ! D-amino acid transmembrane transporter activity
is_a: GO:0043865 ! methionine transmembrane transporter activity
relationship: part_of GO:0048473 ! D-methionine transmembrane transport
+property_value: skos:exactMatch EC:7.4.2.11
+property_value: skos:exactMatch RHEA:29767
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-08-07T15:59:50Z
@@ -196735,7 +203526,6 @@
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:mah]
synonym: "positive regulation of penicillin metabolism" EXACT []
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0042762 ! regulation of sulfur metabolic process
is_a: GO:0043455 ! regulation of secondary metabolic process
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
@@ -196752,7 +203542,6 @@
synonym: "regulation of penicillin catabolism" EXACT []
synonym: "regulation of penicillin degradation" EXACT []
is_a: GO:0009894 ! regulation of catabolic process
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0042762 ! regulation of sulfur metabolic process
is_a: GO:0043455 ! regulation of secondary metabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
@@ -196770,7 +203559,6 @@
synonym: "negative regulation of penicillin degradation" EXACT []
is_a: GO:0009895 ! negative regulation of catabolic process
is_a: GO:0033247 ! regulation of penicillin catabolic process
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0042317 ! penicillin catabolic process
@@ -197166,6 +203954,8 @@
xref: RHEA:32787
is_a: GO:0033285 ! ATPase-coupled monocarboxylic acid transmembrane transporter activity
relationship: part_of GO:0051470 ! ectoine transmembrane transport
+property_value: skos:exactMatch RHEA:32787
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033288
@@ -197878,13 +204668,17 @@
synonym: "UDP-L-arabinose biosynthesis" EXACT []
synonym: "UDP-L-arabinose formation" EXACT []
synonym: "UDP-L-arabinose synthesis" EXACT []
+xref: MetaCyc:PWY-63
+xref: MetaCyc:PWY-82
is_a: GO:0009226 ! nucleotide-sugar biosynthetic process
is_a: GO:0033356 ! UDP-L-arabinose metabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-63
+property_value: skos:narrowMatch MetaCyc:PWY-82
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
id: GO:0033359
-name: lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate
+name: L-lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps." [GOC:mah, MetaCyc:DAPLYSINESYN-PWY]
synonym: "lysine anabolism via diaminopimelate and N-succinyl-2-amino-6-ketopimelate" EXACT []
@@ -197893,12 +204687,13 @@
synonym: "lysine formation via diaminopimelate and N-succinyl-2-amino-6-ketopimelate" EXACT []
synonym: "lysine synthesis via diaminopimelate and N-succinyl-2-amino-6-ketopimelate" EXACT []
xref: MetaCyc:DAPLYSINESYN-PWY
-is_a: GO:0009089 ! lysine biosynthetic process via diaminopimelate
+is_a: GO:0009089 ! L-lysine biosynthetic process via diaminopimelate
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30820" xsd:anyURI
[Term]
id: GO:0033360
-name: lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate
+name: L-lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps." [GOC:mah, MetaCyc:PWY-2941]
synonym: "lysine anabolism via diaminopimelate and L-2-acetamido-6-oxoheptanedioate" EXACT []
@@ -197907,11 +204702,12 @@
synonym: "lysine formation via diaminopimelate and L-2-acetamido-6-oxoheptanedioate" EXACT []
synonym: "lysine synthesis via diaminopimelate and L-2-acetamido-6-oxoheptanedioate" EXACT []
xref: MetaCyc:PWY-2941
-is_a: GO:0009089 ! lysine biosynthetic process via diaminopimelate
+is_a: GO:0009089 ! L-lysine biosynthetic process via diaminopimelate
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30820" xsd:anyURI
[Term]
id: GO:0033361
-name: lysine biosynthetic process via diaminopimelate, dehydrogenase pathway
+name: L-lysine biosynthetic process via diaminopimelate, dehydrogenase pathway
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in a single enzymatic step." [GOC:mah, GOC:pr, MetaCyc:PWY-2942]
synonym: "lysine anabolism via diaminopimelate, dehydrogenase pathway" EXACT []
@@ -197919,12 +204715,13 @@
synonym: "lysine formation via diaminopimelate, dehydrogenase pathway" EXACT []
synonym: "lysine synthesis via diaminopimelate, dehydrogenase pathway" EXACT []
xref: MetaCyc:PWY-2942
-is_a: GO:0009089 ! lysine biosynthetic process via diaminopimelate
+is_a: GO:0009089 ! L-lysine biosynthetic process via diaminopimelate
relationship: has_part GO:0047850 ! diaminopimelate dehydrogenase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30820" xsd:anyURI
[Term]
id: GO:0033362
-name: lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway
+name: L-lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in two enzymatic steps." [GOC:mah, GOC:pr, MetaCyc:PWY-5097]
synonym: "lysine anabolism via diaminopimelate, diaminopimelate-aminotransferase pathway" EXACT []
@@ -197932,9 +204729,10 @@
synonym: "lysine formation via diaminopimelate, diaminopimelate-aminotransferase pathway" EXACT []
synonym: "lysine synthesis via diaminopimelate, diaminopimelate-aminotransferase pathway" EXACT []
xref: MetaCyc:PWY-5097
-is_a: GO:0009089 ! lysine biosynthetic process via diaminopimelate
+is_a: GO:0009089 ! L-lysine biosynthetic process via diaminopimelate
relationship: has_part GO:0008837 ! diaminopimelate epimerase activity
relationship: has_part GO:0010285 ! L,L-diaminopimelate aminotransferase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30820" xsd:anyURI
[Term]
id: GO:0033363
@@ -198204,9 +205002,13 @@
synonym: "geranylgeranyl diphosphate biosynthesis" EXACT []
synonym: "geranylgeranyl diphosphate formation" EXACT []
synonym: "geranylgeranyl diphosphate synthesis" EXACT []
+xref: MetaCyc:PWY-5121
+xref: MetaCyc:PWY-5910
is_a: GO:0008654 ! phospholipid biosynthetic process
is_a: GO:0016114 ! terpenoid biosynthetic process
is_a: GO:0033385 ! geranylgeranyl diphosphate metabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-5121
+property_value: skos:narrowMatch MetaCyc:PWY-5910
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -198233,8 +205035,9 @@
synonym: "putrescine formation from arginine" EXACT []
synonym: "putrescine synthesis from arginine" EXACT []
is_a: GO:0006525 ! arginine metabolic process
-is_a: GO:0009064 ! glutamine family amino acid metabolic process
is_a: GO:0009446 ! putrescine biosynthetic process
+is_a: GO:0170033 ! L-amino acid metabolic process
+is_a: GO:0170039 ! proteinogenic amino acid metabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
[Term]
@@ -199124,7 +205927,6 @@
synonym: "indoleacetic acid amide conjugate synthesis" EXACT []
xref: MetaCyc:PWY-1782
is_a: GO:0033474 ! indoleacetic acid conjugate biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
[Term]
id: GO:0033476
@@ -199239,6 +206041,7 @@
is_a: GO:0009813 ! flavonoid biosynthetic process
is_a: GO:1901038 ! cyanidin 3-O-glucoside metabolic process
is_a: GO:1901806 ! beta-glucoside biosynthetic process
+property_value: skos:broadMatch MetaCyc:PWY-5125
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
[Term]
@@ -199265,6 +206068,7 @@
synonym: "pelargonidin 3-O-glucoside synthesis" EXACT []
is_a: GO:0009813 ! flavonoid biosynthetic process
is_a: GO:1901806 ! beta-glucoside biosynthetic process
+property_value: skos:broadMatch MetaCyc:PWY-5125
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
[Term]
@@ -199360,6 +206164,7 @@
is_a: GO:0072330 ! monocarboxylic acid biosynthetic process
is_a: GO:0120255 ! olefinic compound biosynthetic process
is_a: GO:1901503 ! ether biosynthetic process
+property_value: skos:broadMatch MetaCyc:PWY-5168
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
[Term]
@@ -199387,6 +206192,7 @@
is_a: GO:0072330 ! monocarboxylic acid biosynthetic process
is_a: GO:0120255 ! olefinic compound biosynthetic process
is_a: GO:1901503 ! ether biosynthetic process
+property_value: skos:broadMatch MetaCyc:PWY-5168
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
[Term]
@@ -199502,15 +206308,17 @@
[Term]
id: GO:0033508
-name: L-glutamate catabolic process to butyrate
+name: L-glutamate catabolic process to pyruvate
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of L-glutamate into other compounds, including butyrate." [GOC:mah, MetaCyc:PWY-5087]
+def: "The chemical reactions and pathways resulting in the breakdown of L-glutamate into pyruvate." [MetaCyc:PWY-5087]
synonym: "glutamate breakdown to butyrate" EXACT []
synonym: "glutamate degradation to butyrate" EXACT []
xref: MetaCyc:PWY-5087
+is_a: GO:0006090 ! pyruvate metabolic process
is_a: GO:0006538 ! L-glutamate catabolic process
-is_a: GO:0019605 ! butyrate metabolic process
+is_a: GO:0019665 ! amino acid fermentation
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31218" xsd:anyURI
[Term]
id: GO:0033509
@@ -199522,6 +206330,7 @@
xref: MetaCyc:PWY-5088
is_a: GO:0006538 ! L-glutamate catabolic process
is_a: GO:0019541 ! propionate metabolic process
+is_a: GO:0019665 ! amino acid fermentation
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
[Term]
@@ -199548,9 +206357,9 @@
[Term]
id: GO:0033512
-name: L-lysine catabolic process to acetyl-CoA via saccharopine
+name: L-lysine catabolic process to acetyl-CoA via L-saccharopine
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine." [GOC:mah, MetaCyc:LYSINE-DEG1-PWY]
+def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-saccharopine." [GOC:mah, MetaCyc:LYSINE-DEG1-PWY]
synonym: "L-lysine breakdown to acetyl-CoA via saccharopine" EXACT []
synonym: "L-lysine degradation to acetyl-CoA via saccharopine" EXACT []
xref: MetaCyc:LYSINE-DEG1-PWY
@@ -199570,11 +206379,13 @@
id: GO:0033514
name: L-lysine catabolic process to acetyl-CoA via L-pipecolate
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate." [GOC:mah, MetaCyc:PWY-5283]
+def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate." [GOC:mah, MetaCyc:PWY66-425]
synonym: "L-lysine breakdown to acetyl-CoA via L-pipecolate" EXACT []
synonym: "L-lysine degradation to acetyl-CoA via L-pipecolate" EXACT []
-xref: MetaCyc:PWY-5283
+xref: MetaCyc:PWY66-425
is_a: GO:0019474 ! L-lysine catabolic process to acetyl-CoA
+property_value: skos:exactMatch MetaCyc:PWY66-425
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30820" xsd:anyURI
[Term]
id: GO:0033515
@@ -199584,18 +206395,20 @@
synonym: "L-lysine breakdown using lysine 6-aminotransferase" EXACT [GOC:mah]
synonym: "L-lysine degradation using lysine 6-aminotransferase" EXACT [GOC:mah]
xref: MetaCyc:PWY-5298
-is_a: GO:0019474 ! L-lysine catabolic process to acetyl-CoA
+is_a: GO:0019477 ! L-lysine catabolic process
[Term]
id: GO:0033516
-name: L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine
+name: obsolete L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine." [GOC:mah, MetaCyc:PWY-702]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine." [GOC:mah, MetaCyc:PWY-702]
+comment: The reason for obsoletion is that this term is a duplicate of GO:0019283 and was added in error.
synonym: "L-methionine anabolism from homoserine via O-phospho-L-homoserine and cystathionine" EXACT [GOC:mah]
synonym: "L-methionine formation from homoserine via O-phospho-L-homoserine and cystathionine" EXACT [GOC:mah]
synonym: "L-methionine synthesis from homoserine via O-phospho-L-homoserine and cystathionine" EXACT [GOC:mah]
synonym: "methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine" EXACT [GOC:mah]
-is_a: GO:0019279 ! L-methionine biosynthetic process from L-homoserine via cystathionine
+is_obsolete: true
+replaced_by: GO:0019283
[Term]
id: GO:0033517
@@ -200049,6 +206862,7 @@
xref: RHEA:58108
is_a: GO:0019213 ! deacetylase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch RHEA:58108
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22833" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27528" xsd:anyURI
@@ -200072,6 +206886,8 @@
xref: Reactome:R-HSA-9709098 "DHFR dimer reduces FOLA to DHF"
xref: RHEA:31103
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:31103
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033561
@@ -200310,7 +207126,9 @@
synonym: "tyrosine biosynthetic process from chorismate via L-arogenate" BROAD []
xref: MetaCyc:PWY-3461
is_a: GO:0006571 ! L-tyrosine biosynthetic process
+is_a: GO:0009095 ! aromatic amino acid family biosynthetic process, prephenate pathway
is_a: GO:0046417 ! chorismate metabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31091" xsd:anyURI
[Term]
id: GO:0033585
@@ -200336,7 +207154,9 @@
synonym: "L-phenylalanine synthesis from chorismate via L-arogenate" EXACT []
xref: MetaCyc:PWY-3462
is_a: GO:0009094 ! L-phenylalanine biosynthetic process
+is_a: GO:0009095 ! aromatic amino acid family biosynthetic process, prephenate pathway
is_a: GO:0046417 ! chorismate metabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31091" xsd:anyURI
[Term]
id: GO:0033588
@@ -200566,6 +207386,9 @@
xref: MetaCyc:RXN0-1382
xref: RHEA:16545
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.16
+property_value: skos:exactMatch RHEA:16545
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033609
@@ -201456,6 +208279,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:jl]
xref: EC:1.5.7.-
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.7.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033695
@@ -201464,6 +208289,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule." [EC:1.17.5.-, GOC:mah]
xref: EC:1.17.5.-
is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups
+property_value: skos:exactMatch EC:1.17.5.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033696
@@ -201519,7 +208346,12 @@
synonym: "DNA de-adenylation" RELATED []
synonym: "DNA deadenylation" RELATED []
xref: EC:3.6.1.71
+xref: RHEA:52128
+xref: RHEA:52132
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.71
+property_value: skos:narrowMatch RHEA:52128
+property_value: skos:narrowMatch RHEA:52132
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30724" xsd:anyURI
[Term]
@@ -201542,6 +208374,9 @@
xref: MetaCyc:DTDP-GALACTOSE-6-DEHYDROGENASE-RXN
xref: RHEA:12396
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.186
+property_value: skos:exactMatch RHEA:12396
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033702
@@ -201554,6 +208389,9 @@
xref: MetaCyc:RXN-9397
xref: RHEA:14825
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.275
+property_value: skos:exactMatch RHEA:14825
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033703
@@ -201568,7 +208406,10 @@
xref: MetaCyc:1.1.1.277-RXN
xref: RHEA:22944
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.277
+property_value: skos:exactMatch RHEA:22944
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29311" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033704
@@ -201581,7 +208422,10 @@
xref: MetaCyc:1.1.1.278-RXN
xref: RHEA:18137
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.278
+property_value: skos:exactMatch RHEA:18137
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29311" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033705
@@ -201595,7 +208439,10 @@
synonym: "Rmd" RELATED [EC:1.1.1.281]
xref: EC:1.1.1.281
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch MetaCyc:GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN
+property_value: skos:exactMatch EC:1.1.1.281
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033706
@@ -201620,8 +208467,14 @@
synonym: "2'-deoxymugineic acid:NAD(P)+ 3''-oxidoreductase activity" RELATED [EC:1.1.1.285]
xref: EC:1.1.1.285
xref: MetaCyc:1.1.1.285-RXN
+xref: RHEA:16137
+xref: RHEA:16141
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.285
+property_value: skos:narrowMatch RHEA:16137
+property_value: skos:narrowMatch RHEA:16141
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29311" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033708
@@ -201633,7 +208486,11 @@
synonym: "PH1722" RELATED [EC:1.1.1.286]
xref: EC:1.1.1.286
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch MetaCyc:ISOCITRATE-DEHYDROGENASE-NAD+-RXN
+property_value: skos:broadMatch MetaCyc:RXN-7970
+property_value: skos:exactMatch EC:1.1.1.286
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033709
@@ -201647,7 +208504,20 @@
synonym: "D-arabinitol:NADP+ dehydrogenase activity" BROAD [EC:1.1.1.287]
synonym: "NADP+-dependent D-arabinitol dehydrogenase activity" BROAD [EC:1.1.1.287]
xref: EC:1.1.1.287
+xref: KEGG_REACTION:R07143
+xref: KEGG_REACTION:R07144
+xref: MetaCyc:RXN-7971
+xref: MetaCyc:RXN-7972
+xref: RHEA:11868
+xref: RHEA:21276
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.287
+property_value: skos:narrowMatch KEGG_REACTION:R07143
+property_value: skos:narrowMatch KEGG_REACTION:R07144
+property_value: skos:narrowMatch MetaCyc:RXN-7971
+property_value: skos:narrowMatch MetaCyc:RXN-7972
+property_value: skos:narrowMatch RHEA:11868
+property_value: skos:narrowMatch RHEA:21276
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28859" xsd:anyURI
[Term]
@@ -201666,6 +208536,9 @@
xref: MetaCyc:ERYTHRON4PDEHYDROG-RXN
xref: RHEA:18829
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.290
+property_value: skos:exactMatch RHEA:18829
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033712
@@ -201679,6 +208552,9 @@
xref: MetaCyc:1.1.1.292-RXN
xref: RHEA:24208
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.292
+property_value: skos:exactMatch RHEA:24208
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033713
@@ -201690,6 +208566,9 @@
xref: MetaCyc:CHOLINE-OXIDASE-RXN
xref: RHEA:13505
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.17
+property_value: skos:exactMatch RHEA:13505
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033714
@@ -201704,6 +208583,9 @@
xref: MetaCyc:SECONDARY-ALCOHOL-OXIDASE-RXN
xref: RHEA:23180
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.18
+property_value: skos:exactMatch RHEA:23180
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033715
@@ -201715,6 +208597,9 @@
xref: MetaCyc:NUCLEOSIDE-OXIDASE-RXN
xref: RHEA:28651
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.28
+property_value: skos:exactMatch RHEA:28651
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033716
@@ -201727,6 +208612,9 @@
xref: MetaCyc:1.1.3.39-RXN
xref: RHEA:15489
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.39
+property_value: skos:exactMatch RHEA:15489
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033717
@@ -201745,6 +208633,9 @@
xref: MetaCyc:GLUCONATE-2-DEHYDROGENASE-RXN
xref: RHEA:12769
is_a: GO:0008875 ! gluconate dehydrogenase activity
+property_value: skos:exactMatch EC:1.1.99.3
+property_value: skos:exactMatch RHEA:12769
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033718
@@ -201757,7 +208648,18 @@
synonym: "pyranose:acceptor oxidoreductase activity" RELATED [EC:1.1.99.29]
synonym: "quinone-dependent pyranose dehydrogenase activity" RELATED [EC:1.1.99.29]
xref: EC:1.1.99.29
+xref: MetaCyc:RXN-7961
+xref: MetaCyc:RXN-7962
+xref: MetaCyc:RXN-7963
+xref: MetaCyc:RXN-7965
+xref: MetaCyc:RXN-7966
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.29
+property_value: skos:narrowMatch MetaCyc:RXN-7961
+property_value: skos:narrowMatch MetaCyc:RXN-7962
+property_value: skos:narrowMatch MetaCyc:RXN-7963
+property_value: skos:narrowMatch MetaCyc:RXN-7965
+property_value: skos:narrowMatch MetaCyc:RXN-7966
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -201774,6 +208676,9 @@
xref: MetaCyc:1.1.99.30-RXN
xref: RHEA:23664
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.30
+property_value: skos:exactMatch RHEA:23664
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033720
@@ -201788,6 +208693,9 @@
xref: RHEA:15749
xref: UM-BBD_reactionID:r1048
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.31
+property_value: skos:exactMatch RHEA:15749
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033721
@@ -201801,6 +208709,8 @@
xref: MetaCyc:ALDEHYDE-DEHYDROGENASE-NADP+-RXN
xref: RHEA:11888
is_a: GO:0004030 ! aldehyde dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.2.1.4
+property_value: skos:exactMatch RHEA:11888
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29544" xsd:anyURI
[Term]
@@ -201812,7 +208722,13 @@
synonym: "malonic semialdehyde dehydrogenase activity" RELATED [EC:1.2.1.15]
xref: EC:1.2.1.15
xref: MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDROGENASE-RXN
+xref: RHEA:20041
+xref: RHEA:20045
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.15
+property_value: skos:narrowMatch RHEA:20041
+property_value: skos:narrowMatch RHEA:20045
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033723
@@ -201823,6 +208739,9 @@
xref: EC:1.2.1.69
xref: RHEA:16677
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.69
+property_value: skos:exactMatch RHEA:16677
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033726
@@ -201836,6 +208755,9 @@
xref: MetaCyc:1.2.7.5-RXN
xref: RHEA:16421
is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.2.7.5
+property_value: skos:exactMatch RHEA:16421
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033727
@@ -201849,7 +208771,9 @@
xref: EC:1.2.99.7
xref: MetaCyc:1.2.99.7-RXN
is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors
+property_value: skos:exactMatch EC:1.2.99.7
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033728
@@ -201862,8 +208786,18 @@
synonym: "[4-vinyl]chlorophyllide a reductase activity" RELATED [EC:1.3.1.75]
synonym: "chlorophyllide-a:NADP+ oxidoreductase activity" RELATED [EC:1.3.1.75]
xref: EC:1.3.1.75
+xref: MetaCyc:RXN-5286
+xref: MetaCyc:RXN1F-72
+xref: RHEA:14449
+xref: RHEA:48884
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.75
+property_value: skos:narrowMatch MetaCyc:RXN-5286
+property_value: skos:narrowMatch MetaCyc:RXN1F-72
+property_value: skos:narrowMatch RHEA:14449
+property_value: skos:narrowMatch RHEA:48884
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033729
@@ -201877,6 +208811,8 @@
xref: EC:1.3.1.77
xref: MetaCyc:RXN-10693
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.77
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033730
@@ -201893,6 +208829,9 @@
xref: MetaCyc:RXN-5682
xref: RHEA:15417
is_a: GO:0033731 ! arogenate dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.3.1.78
+property_value: skos:exactMatch RHEA:15417
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033731
@@ -201905,6 +208844,8 @@
xref: EC:1.3.1.79
xref: MetaCyc:RXN-14476
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.79
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033732
@@ -201918,6 +208859,9 @@
xref: MetaCyc:RXN-11181
xref: RHEA:10692
is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.3.3.11
+property_value: skos:exactMatch RHEA:10692
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033734
@@ -201931,6 +208875,9 @@
xref: RHEA:20876
xref: UM-BBD_reactionID:r0330
is_a: GO:0052890 ! oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
+property_value: skos:exactMatch EC:1.3.8.3
+property_value: skos:exactMatch RHEA:20876
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033735
@@ -201949,7 +208896,13 @@
xref: KEGG_REACTION:R07164
xref: KEGG_REACTION:R07165
xref: MetaCyc:1.4.1.21-RXN
+xref: RHEA:11784
+xref: RHEA:11788
is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors
+property_value: skos:exactMatch EC:1.4.1.21
+property_value: skos:narrowMatch RHEA:11784
+property_value: skos:narrowMatch RHEA:11788
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-01-20T17:39:50Z
@@ -201968,6 +208921,9 @@
xref: MetaCyc:1.4.3.20-RXN
xref: RHEA:22548
is_a: GO:0001716 ! L-amino-acid oxidase activity
+property_value: skos:exactMatch EC:1.4.3.20
+property_value: skos:exactMatch RHEA:22548
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033737
@@ -201994,6 +208950,9 @@
xref: MetaCyc:RXN-5061
xref: RHEA:14229
is_a: GO:0033694 ! oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.5.7.1
+property_value: skos:exactMatch RHEA:14229
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033739
@@ -202015,6 +208974,9 @@
xref: RHEA:13409
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.7.1.13
+property_value: skos:exactMatch RHEA:13409
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033740
@@ -202025,6 +208987,8 @@
xref: MetaCyc:RXN-13570
xref: RHEA:45036
is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.7.2.9
+property_value: skos:exactMatch RHEA:45036
[Term]
id: GO:0033741
@@ -202040,6 +209004,9 @@
xref: MetaCyc:1.8.4.9-RXN
xref: RHEA:14141
is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
+property_value: skos:exactMatch EC:1.8.4.9
+property_value: skos:exactMatch RHEA:14141
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033743
@@ -202067,6 +209034,9 @@
xref: RHEA:24164
is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:1.8.4.12
+property_value: skos:exactMatch RHEA:24164
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30723" xsd:anyURI
[Term]
@@ -202089,6 +209059,9 @@
xref: MetaCyc:1.8.4.13-RXN
xref: RHEA:19993
is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
+property_value: skos:broadMatch EC:1.8.4.11
+property_value: skos:exactMatch EC:1.8.4.13
+property_value: skos:exactMatch RHEA:19993
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30723" xsd:anyURI
[Term]
@@ -202105,6 +209078,9 @@
xref: MetaCyc:1.8.4.14-RXN
xref: RHEA:21260
is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
+property_value: skos:exactMatch EC:1.8.4.14
+property_value: skos:exactMatch RHEA:21260
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30723" xsd:anyURI
[Term]
@@ -202119,6 +209095,9 @@
synonym: "histone H3R2me demethylase activity" EXACT []
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0141052 ! histone H3 demethylase activity
+property_value: skos:broadMatch RHEA:58352
+property_value: skos:broadMatch RHEA:58356
+property_value: skos:broadMatch RHEA:58472
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21089" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29636" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -202134,8 +209113,7 @@
synonym: "versatile peroxidase activity" EXACT []
synonym: "VP" RELATED [EC:1.11.1.16]
is_obsolete: true
-replaced_by: GO:0004601
-consider: GO:0052750
+replaced_by: GO:0052750
[Term]
id: GO:0033748
@@ -202152,6 +209130,9 @@
xref: MetaCyc:RXN0-4141
xref: RHEA:12116
is_a: GO:0016695 ! oxidoreductase activity, acting on hydrogen as donor
+property_value: skos:exactMatch EC:1.12.99.6
+property_value: skos:exactMatch MetaCyc:RXN0-4141
+property_value: skos:exactMatch RHEA:12116
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -202165,6 +209146,9 @@
synonym: "histone H4R3me demethylase activity" EXACT []
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0141058 ! histone H4 demethylase activity
+property_value: skos:broadMatch RHEA:58352
+property_value: skos:broadMatch RHEA:58356
+property_value: skos:broadMatch RHEA:58472
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21089" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24868" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29636" xsd:anyURI
@@ -202207,6 +209191,9 @@
xref: EC:1.13.11.50
xref: RHEA:12877
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.50
+property_value: skos:exactMatch RHEA:12877
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033754
@@ -202219,6 +209206,9 @@
xref: MetaCyc:RXN-8664
xref: RHEA:14189
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:broadMatch EC:1.13.11.52
+property_value: skos:exactMatch MetaCyc:RXN-8664
+property_value: skos:exactMatch RHEA:14189
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30559" xsd:anyURI
@@ -202235,6 +209225,9 @@
xref: MetaCyc:1.13.11.55-RXN
xref: RHEA:13957
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.55
+property_value: skos:exactMatch RHEA:13957
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033756
@@ -202248,6 +209241,9 @@
xref: RHEA:20417
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
is_a: GO:0045289 ! luciferin monooxygenase activity
+property_value: skos:exactMatch EC:1.13.12.13
+property_value: skos:exactMatch RHEA:20417
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033757
@@ -202264,6 +209260,9 @@
xref: RHEA:16589
xref: Wikipedia:Glucoside_3-dehydrogenase
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.13
+property_value: skos:exactMatch RHEA:16589
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033758
@@ -202277,6 +209276,9 @@
xref: MetaCyc:1.14.11.21-RXN
xref: RHEA:20021
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.21
+property_value: skos:exactMatch RHEA:20021
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033759
@@ -202291,6 +209293,9 @@
xref: RHEA:10448
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
relationship: part_of GO:0051553 ! flavone biosynthetic process
+property_value: skos:exactMatch EC:1.14.20.5
+property_value: skos:exactMatch RHEA:10448
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033760
@@ -202304,6 +209309,9 @@
xref: MetaCyc:1.14.11.24-RXN
xref: RHEA:12200
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.24
+property_value: skos:exactMatch RHEA:12200
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033761
@@ -202313,7 +209321,20 @@
synonym: "IDS2" RELATED [EC:1.14.11.25]
synonym: "mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" RELATED [EC:1.14.11.25]
xref: EC:1.14.11.25
+xref: KEGG_REACTION:R07186
+xref: KEGG_REACTION:R07187
+xref: MetaCyc:RXN-7982
+xref: MetaCyc:RXN-7983
+xref: RHEA:14509
+xref: RHEA:20065
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.25
+property_value: skos:narrowMatch KEGG_REACTION:R07186
+property_value: skos:narrowMatch KEGG_REACTION:R07187
+property_value: skos:narrowMatch MetaCyc:RXN-7982
+property_value: skos:narrowMatch MetaCyc:RXN-7983
+property_value: skos:narrowMatch RHEA:14509
+property_value: skos:narrowMatch RHEA:20065
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -202335,6 +209356,9 @@
xref: MetaCyc:1.14.11.28-RXN
xref: RHEA:20265
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.28
+property_value: skos:exactMatch RHEA:20265
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033764
@@ -202344,6 +209368,7 @@
xref: Reactome:R-HSA-9758682 "AKR1C1 hydrogenates PREDN,PREDL"
is_a: GO:0016229 ! steroid dehydrogenase activity
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.1.1.-
[Term]
id: GO:0033765
@@ -202352,6 +209377,7 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative." [GOC:mah]
is_a: GO:0016229 ! steroid dehydrogenase activity
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:broadMatch EC:1.3.99.-
[Term]
id: GO:0033766
@@ -202365,6 +209391,9 @@
xref: MetaCyc:1.14.13.61-RXN
xref: RHEA:22080
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.61
+property_value: skos:exactMatch RHEA:22080
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033767
@@ -202379,6 +209408,9 @@
xref: RHEA:22916
xref: UM-BBD_reactionID:r0756
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.84
+property_value: skos:exactMatch RHEA:22916
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033768
@@ -202394,7 +209426,20 @@
def: "Catalysis of the reactions: 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin II or glyceollin III + NADP+ + 2 H2O, and 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin I + NADP+ + 2 H2O." [EC:1.14.14.135]
synonym: "dimethylallyl-3,6a,9-trihydroxypterocarpan cyclase activity" EXACT [EC:1.14.14.135]
xref: EC:1.14.14.135
+xref: MetaCyc:RXN-4511
+xref: MetaCyc:RXN-4512
+xref: MetaCyc:RXN-4513
+xref: RHEA:22844
+xref: RHEA:26047
+xref: RHEA:26051
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.135
+property_value: skos:narrowMatch MetaCyc:RXN-4511
+property_value: skos:narrowMatch MetaCyc:RXN-4512
+property_value: skos:narrowMatch MetaCyc:RXN-4513
+property_value: skos:narrowMatch RHEA:22844
+property_value: skos:narrowMatch RHEA:26047
+property_value: skos:narrowMatch RHEA:26051
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24841" xsd:anyURI
[Term]
@@ -202406,7 +209451,18 @@
def: "Catalysis of the reactions: liquiritigenin + O2 + [reduced NADPH--hemoprotein reductase] = 2,4',7-trihydroxyisoflavanone + H2O + [oxidized NADPH--hemoprotein reductase] and (2S)-naringenin + O2 + [reduced NADPH--hemoprotein reductase] = 2,4',5,7-tetrahydroxyisoflavanone + H2O + [oxidized NADPH--hemoprotein reductase]." [EC:1.14.14.87]
synonym: "isoflavonoid synthase" BROAD [EC:1.14.14.87]
xref: EC:1.14.14.87
+xref: MetaCyc:RXN-1541
+xref: MetaCyc:RXN-3283
+xref: MetaCyc:RXN-7750
+xref: RHEA:31723
+xref: RHEA:35487
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.87
+property_value: skos:narrowMatch MetaCyc:RXN-1541
+property_value: skos:narrowMatch MetaCyc:RXN-3283
+property_value: skos:narrowMatch MetaCyc:RXN-7750
+property_value: skos:narrowMatch RHEA:31723
+property_value: skos:narrowMatch RHEA:35487
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23415" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -202421,7 +209477,10 @@
xref: MetaCyc:RXN-19645
xref: RHEA:57584
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.162
+property_value: skos:exactMatch RHEA:57584
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25989" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033772
@@ -202435,6 +209494,9 @@
xref: MetaCyc:RXN-13192
xref: RHEA:55448
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.81
+property_value: skos:exactMatch MetaCyc:RXN-13192
+property_value: skos:exactMatch RHEA:55448
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -202449,8 +209511,11 @@
xref: MetaCyc:RXN-11846
xref: RHEA:18849
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.90
+property_value: skos:exactMatch RHEA:18849
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033774
@@ -202472,6 +209537,9 @@
xref: MetaCyc:1.14.13.91-RXN
xref: RHEA:14237
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.136
+property_value: skos:exactMatch RHEA:14237
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033776
@@ -202485,6 +209553,9 @@
xref: MetaCyc:1.14.13.92-RXN
xref: RHEA:10124
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.92
+property_value: skos:exactMatch RHEA:10124
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033777
@@ -202501,6 +209572,9 @@
xref: MetaCyc:1.14.13.94-RXN
xref: RHEA:18857
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.138
+property_value: skos:exactMatch RHEA:18857
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033778
@@ -202508,6 +209582,9 @@
namespace: molecular_function
def: "OBSOLETE. Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H+ + NADPH + O2 = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H2O + NADP+." [PMID:10051404, PMID:1400444]
comment: This term was obsoleted because it represents a specific susbstrate of sterol 12-alpha-hydroxylase activity ; GO:0008397.
+xref: Reactome:R-HSA-192157 "CYP8B1 12-hydroxylates 4CHOL7aOLONE"
+xref: Reactome:R-HSA-193709 "CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL"
+xref: Reactome:R-HSA-193845 "CYP8B1 12-hydroxylates 4CHOL7a,27DONE"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24843" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29331" xsd:anyURI
is_obsolete: true
@@ -202535,9 +209612,15 @@
synonym: "taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) activity" RELATED []
xref: EC:1.14.14.57
xref: MetaCyc:RXN-7977
+xref: RHEA:17857
+xref: RHEA:23644
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.57
+property_value: skos:narrowMatch RHEA:17857
+property_value: skos:narrowMatch RHEA:23644
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22678" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27695" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033781
@@ -202556,6 +209639,9 @@
xref: Reactome:R-HSA-192061 "CYP46A1 24-hydroxylates CHOL"
xref: RHEA:22716
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.25
+property_value: skos:exactMatch RHEA:22716
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033782
@@ -202571,6 +209657,8 @@
xref: RHEA:46124
is_a: GO:0008387 ! steroid 7-alpha-hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.26
+property_value: skos:exactMatch RHEA:46124
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18243" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29041" xsd:anyURI
@@ -202585,8 +209673,17 @@
synonym: "CYP7B1" RELATED [EC:1.14.14.29]
synonym: "CYP7B1 oxysterol 7alpha-hydroxylase activity" RELATED [EC:1.14.14.29]
xref: EC:1.14.14.29
+xref: MetaCyc:RXN-7980
+xref: MetaCyc:RXN-7981
+xref: RHEA:19041
+xref: RHEA:24308
is_a: GO:0008387 ! steroid 7-alpha-hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.29
+property_value: skos:narrowMatch MetaCyc:RXN-7980
+property_value: skos:narrowMatch MetaCyc:RXN-7981
+property_value: skos:narrowMatch RHEA:19041
+property_value: skos:narrowMatch RHEA:24308
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29041" xsd:anyURI
@@ -202603,6 +209700,9 @@
xref: MetaCyc:1.14.13.101-RXN
xref: RHEA:11420
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.101
+property_value: skos:exactMatch RHEA:11420
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033785
@@ -202614,6 +209714,9 @@
xref: MetaCyc:RXN0-4341
xref: RHEA:27473
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.167
+property_value: skos:exactMatch RHEA:27473
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033786
@@ -202625,6 +209728,8 @@
xref: MetaCyc:RXN0-4342
xref: RHEA:27465
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch RHEA:27465
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033787
@@ -202643,6 +209748,9 @@
xref: Reactome:R-HSA-3149519 "MMACHC decyanates CNCbl"
xref: RHEA:16113
is_a: GO:0016723 ! oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.16.1.6
+property_value: skos:exactMatch RHEA:16113
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033788
@@ -202655,6 +209763,9 @@
xref: MetaCyc:RXN-1484
xref: RHEA:10616
is_a: GO:0016726 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.17.1.3
+property_value: skos:exactMatch RHEA:10616
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033789
@@ -202668,13 +209779,18 @@
xref: MetaCyc:1.17.5.1-RXN
xref: RHEA:15705
is_a: GO:0033695 ! oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.17.5.1
+property_value: skos:exactMatch RHEA:15705
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033790
-name: hydroxymethylfurfural reductase activity
+name: obsolete hydroxymethylfurfural reductase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+." [GOC:jp, GOC:mah, PMID:15338422, PMID:16652391]
-is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+def: "OBSOLETE. Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+." [GOC:jp, GOC:mah, PMID:15338422, PMID:16652391]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31101" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0033791
@@ -202691,6 +209807,9 @@
xref: MetaCyc:1.17.99.3-RXN
xref: RHEA:15733
is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups
+property_value: skos:exactMatch EC:1.17.99.3
+property_value: skos:exactMatch RHEA:15733
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033792
@@ -202705,7 +209824,10 @@
xref: EC:1.1.1.395
xref: RHEA:55380
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.395
+property_value: skos:exactMatch RHEA:55380
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22749" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033793
@@ -202714,7 +209836,22 @@
def: "Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H+ + O2 = aureusidin 6-O-beta-glucoside + H2O, 2 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + 2 H+ + O2 = 2 aureusidin 6-O-beta-glucoside + 2 H2O, and 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + H+ + O2 = bracteatin 6-O-beta-glucoside + H2O. This activity consists of two separate chemical transformations: 3-hydroxylation and oxidative cyclization (2',-dehydrogenation)." [EC:1.21.3.6]
synonym: "2',4,4',6'-tetrahydroxychalcone:oxygen oxidoreductase activity" RELATED [EC:1.21.3.6]
xref: EC:1.21.3.6
+xref: MetaCyc:RXN-3102
+xref: MetaCyc:RXN-6242
+xref: MetaCyc:RXN-8008
+xref: MetaCyc:RXN-8456
+xref: RHEA:34195
+xref: RHEA:34199
+xref: RHEA:34203
is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
+property_value: skos:exactMatch EC:1.21.3.6
+property_value: skos:narrowMatch MetaCyc:RXN-3102
+property_value: skos:narrowMatch MetaCyc:RXN-6242
+property_value: skos:narrowMatch MetaCyc:RXN-8008
+property_value: skos:narrowMatch MetaCyc:RXN-8456
+property_value: skos:narrowMatch RHEA:34195
+property_value: skos:narrowMatch RHEA:34199
+property_value: skos:narrowMatch RHEA:34203
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -202726,6 +209863,9 @@
xref: EC:1.21.4.3
xref: RHEA:12825
is_a: GO:0050485 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor
+property_value: skos:exactMatch EC:1.21.4.3
+property_value: skos:exactMatch RHEA:12825
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033795
@@ -202736,6 +209876,9 @@
xref: EC:1.21.4.4
xref: RHEA:11848
is_a: GO:0050485 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor
+property_value: skos:exactMatch EC:1.21.4.4
+property_value: skos:exactMatch RHEA:11848
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033796
@@ -202748,7 +209891,10 @@
xref: MetaCyc:RXN-8269
xref: RHEA:35591
is_a: GO:0046995 ! oxidoreductase activity, acting on hydrogen as donor, with other known acceptors
+property_value: skos:exactMatch EC:1.12.98.4
+property_value: skos:exactMatch RHEA:35591
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033797
@@ -202762,6 +209908,9 @@
xref: RHEA:14029
xref: UM-BBD_reactionID:r0828
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.97.1.9
+property_value: skos:exactMatch RHEA:14029
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033798
@@ -202778,7 +209927,10 @@
xref: MetaCyc:1.97.1.11-RXN
xref: RHEA:18897
is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond
+property_value: skos:exactMatch EC:1.21.99.3
+property_value: skos:exactMatch RHEA:18897
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033799
@@ -202795,6 +209947,8 @@
xref: RHEA:25629
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.267
+property_value: skos:exactMatch RHEA:25629
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
@@ -202809,6 +209963,9 @@
xref: RHEA:17933
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.150
+property_value: skos:exactMatch RHEA:17933
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033801
@@ -202821,6 +209978,9 @@
xref: RHEA:11432
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.153
+property_value: skos:exactMatch RHEA:11432
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033802
@@ -202836,6 +209996,9 @@
xref: RHEA:21608
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.154
+property_value: skos:exactMatch RHEA:21608
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033803
@@ -202851,6 +210014,9 @@
xref: RHEA:15105
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.155
+property_value: skos:exactMatch RHEA:15105
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033804
@@ -202894,6 +210060,9 @@
xref: EC:2.2.1.8
xref: RHEA:11748
is_a: GO:0016744 ! transketolase or transaldolase activity
+property_value: skos:exactMatch EC:2.2.1.8
+property_value: skos:exactMatch RHEA:11748
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033807
@@ -202922,6 +210091,9 @@
xref: MetaCyc:RXN-3142
xref: RHEA:10584
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.170
+property_value: skos:exactMatch RHEA:10584
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033809
@@ -202936,6 +210108,9 @@
xref: MetaCyc:2.3.1.171-RXN
xref: RHEA:16025
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.171
+property_value: skos:exactMatch RHEA:16025
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033810
@@ -202948,6 +210123,9 @@
xref: MetaCyc:2.3.1.172-RXN
xref: RHEA:21988
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.172
+property_value: skos:exactMatch RHEA:21988
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033811
@@ -202959,6 +210137,9 @@
xref: MetaCyc:2.3.1.173-RXN
xref: RHEA:22160
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.173
+property_value: skos:exactMatch RHEA:22160
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033812
@@ -202970,7 +210151,10 @@
xref: MetaCyc:RXN-3641
xref: RHEA:19481
is_a: GO:0003988 ! acetyl-CoA C-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.174
+property_value: skos:exactMatch RHEA:19481
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28845" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033813
@@ -202992,6 +210176,9 @@
xref: MetaCyc:2.3.1.175-RXN
xref: RHEA:23860
is_a: GO:0016408 ! C-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.175
+property_value: skos:exactMatch RHEA:23860
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033814
@@ -203008,6 +210195,8 @@
xref: MetaCyc:2.3.1.176-RXN
xref: RHEA:16865
is_a: GO:0016408 ! C-acyltransferase activity
+property_value: skos:broadMatch EC:2.3.1.176
+property_value: skos:exactMatch RHEA:16865
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -203021,6 +210210,9 @@
xref: MetaCyc:2.3.1.177-RXN
xref: RHEA:22292
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.177
+property_value: skos:exactMatch RHEA:22292
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033816
@@ -203042,6 +210234,9 @@
xref: MetaCyc:R102-RXN
xref: RHEA:16901
is_a: GO:0016407 ! acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.178
+property_value: skos:exactMatch RHEA:16901
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033818
@@ -203061,6 +210256,9 @@
xref: MetaCyc:2.3.1.180-RXN
xref: RHEA:12080
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.180
+property_value: skos:exactMatch RHEA:12080
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033819
@@ -203081,6 +210279,8 @@
xref: RHEA:17665
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.3.1.181
+property_value: skos:exactMatch RHEA:17665
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22690" xsd:anyURI
[Term]
@@ -203098,6 +210298,8 @@
xref: MetaCyc:2.4.1.26-RXN
is_a: GO:0046527 ! glucosyltransferase activity
is_a: GO:0140097 ! catalytic activity, acting on DNA
+property_value: skos:exactMatch EC:2.4.1.26
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033821
@@ -203115,6 +210317,8 @@
xref: MetaCyc:2.4.1.27-RXN
is_a: GO:0046527 ! glucosyltransferase activity
is_a: GO:0140097 ! catalytic activity, acting on DNA
+property_value: skos:exactMatch EC:2.4.1.27
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033822
@@ -203129,6 +210333,8 @@
xref: EC:2.4.1.28
xref: MetaCyc:2.4.1.28-RXN
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.28
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033823
@@ -203150,6 +210356,9 @@
xref: RHEA:12576
is_a: GO:0046527 ! glucosyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.4.1.66
+property_value: skos:exactMatch RHEA:12576
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033824
@@ -203172,6 +210381,8 @@
xref: EC:2.4.1.161
xref: MetaCyc:2.4.1.161-RXN
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.161
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033826
@@ -203186,6 +210397,8 @@
xref: EC:2.4.1.168
xref: MetaCyc:RXN-12419
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.168
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033827
@@ -203199,6 +210412,8 @@
xref: EC:2.4.1.197
xref: MetaCyc:2.4.1.197-RXN
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.197
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033828
@@ -203215,6 +210430,9 @@
xref: MetaCyc:2.4.1.213-RXN
xref: RHEA:12881
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.213
+property_value: skos:exactMatch RHEA:12881
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033829
@@ -203227,8 +210445,14 @@
xref: MetaCyc:2.4.1.222-RXN
xref: Reactome:R-HSA-1912355 "Glycosylation of Pre-NOTCH by FRINGE"
xref: Reactome:R-HSA-5096538 "Defective LFNG does not transfer GlcNAc to Pre-NOTCH"
+xref: RHEA:70511
+xref: RHEA:70531
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.222
+property_value: skos:narrowMatch RHEA:70511
+property_value: skos:narrowMatch RHEA:70531
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24845" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033830
@@ -203244,6 +210468,9 @@
xref: RHEA:17841
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.4.1.229
+property_value: skos:exactMatch RHEA:17841
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033831
@@ -203256,6 +210483,9 @@
xref: MetaCyc:2.4.1.230-RXN
xref: RHEA:11176
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.230
+property_value: skos:exactMatch RHEA:11176
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033832
@@ -203268,6 +210498,8 @@
xref: MetaCyc:RXN-4441
xref: RHEA:16257
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.231
+property_value: skos:exactMatch RHEA:16257
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28942" xsd:anyURI
[Term]
@@ -203289,6 +210521,8 @@
xref: MetaCyc:2.4.1.234-RXN
xref: RHEA:15709
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.234
+property_value: skos:exactMatch RHEA:15709
[Term]
id: GO:0033835
@@ -203300,8 +210534,17 @@
synonym: "UDP-rhamnose:flavanone-7-O-glucoside-2''-O-rhamnosyltransferase activity" RELATED [EC:2.4.1.236]
xref: EC:2.4.1.236
xref: MetaCyc:RXN-5001
+xref: MetaCyc:RXN-5002
+xref: MetaCyc:RXN-5004
+xref: MetaCyc:RXN-9699
xref: RHEA:15473
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.236
+property_value: skos:exactMatch MetaCyc:RXN-5001
+property_value: skos:exactMatch RHEA:15473
+property_value: skos:narrowMatch MetaCyc:RXN-5002
+property_value: skos:narrowMatch MetaCyc:RXN-5004
+property_value: skos:narrowMatch MetaCyc:RXN-9699
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -203315,6 +210558,9 @@
xref: MetaCyc:2.4.1.237-RXN
xref: RHEA:23164
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.237
+property_value: skos:exactMatch RHEA:23164
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033837
@@ -203328,6 +210574,9 @@
xref: MetaCyc:RXN-8231
xref: RHEA:35627
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.238
+property_value: skos:exactMatch RHEA:35627
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033838
@@ -203339,6 +210588,9 @@
xref: MetaCyc:2.4.1.239-RXN
xref: RHEA:18893
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.239
+property_value: skos:exactMatch RHEA:18893
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033839
@@ -203350,6 +210602,9 @@
xref: MetaCyc:2.4.1.240-RXN
xref: RHEA:23544
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.240
+property_value: skos:exactMatch RHEA:23544
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033840
@@ -203369,8 +210624,13 @@
synonym: "waxy protein" RELATED [EC:2.4.1.242]
xref: EC:2.4.1.242
xref: MetaCyc:2.4.1.242-RXN
+xref: MetaCyc:RXN-14378
xref: RHEA:15873
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.242
+property_value: skos:exactMatch MetaCyc:2.4.1.242-RXN
+property_value: skos:exactMatch RHEA:15873
+property_value: skos:narrowMatch MetaCyc:RXN-14378
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28271" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28811" xsd:anyURI
@@ -203387,6 +210647,8 @@
xref: EC:2.4.1.243
xref: MetaCyc:2.4.1.243-RXN
is_a: GO:0050738 ! fructosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.243
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033842
@@ -203404,6 +210666,9 @@
xref: MetaCyc:2.4.1.244-RXN
xref: RHEA:20493
is_a: GO:0008376 ! acetylgalactosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.244
+property_value: skos:exactMatch MetaCyc:2.4.1.244-RXN
+property_value: skos:exactMatch RHEA:20493
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18752" xsd:anyURI
[Term]
@@ -203415,7 +210680,12 @@
synonym: "uridine diphosphoxylose-xyloglucan 6alpha-xylosyltransferase activity" RELATED [EC:2.4.2.39]
synonym: "xyloglucan 6-alpha-D-xylosyltransferase activity" RELATED [EC:2.4.2.39]
xref: EC:2.4.2.39
+xref: MetaCyc:RXN-12415
+xref: MetaCyc:RXN-9461
is_a: GO:0042285 ! xylosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.39
+property_value: skos:narrowMatch MetaCyc:RXN-12415
+property_value: skos:narrowMatch MetaCyc:RXN-9461
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -203430,6 +210700,8 @@
xref: EC:2.5.1.5
xref: MetaCyc:2.5.1.5-RXN
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.5
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033845
@@ -203449,6 +210721,9 @@
xref: MetaCyc:2.5.1.63-RXN
xref: RHEA:16661
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.63
+property_value: skos:exactMatch RHEA:16661
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033847
@@ -203461,6 +210736,9 @@
xref: MetaCyc:2.5.1.65-RXN
xref: RHEA:10252
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.65
+property_value: skos:exactMatch RHEA:10252
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033848
@@ -203477,6 +210755,9 @@
xref: MetaCyc:2.5.1.66-RXN
xref: RHEA:10556
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.66
+property_value: skos:exactMatch RHEA:10556
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033849
@@ -203490,6 +210771,9 @@
xref: MetaCyc:2.5.1.67-RXN
xref: RHEA:14009
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.67
+property_value: skos:exactMatch RHEA:14009
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033850
@@ -203503,6 +210787,9 @@
xref: MetaCyc:2.5.1.68-RXN
xref: RHEA:23300
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.68
+property_value: skos:exactMatch RHEA:23300
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033851
@@ -203516,6 +210803,9 @@
xref: MetaCyc:2.5.1.69-RXN
xref: RHEA:21676
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.69
+property_value: skos:exactMatch RHEA:21676
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033852
@@ -203532,6 +210822,9 @@
xref: MetaCyc:THYROID-HORMONE-AMINOTRANSFERASE-RXN
xref: RHEA:19133
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.26
+property_value: skos:exactMatch RHEA:19133
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033853
@@ -203547,6 +210840,9 @@
xref: MetaCyc:PREPHENATE-ASP-TRANSAMINE-RXN
xref: RHEA:20445
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.78
+property_value: skos:exactMatch RHEA:20445
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033854
@@ -203562,6 +210858,9 @@
xref: MetaCyc:PREPHENATE-TRANSAMINE-RXN
xref: RHEA:22880
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.79
+property_value: skos:exactMatch RHEA:22880
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033855
@@ -203579,6 +210878,9 @@
xref: MetaCyc:2.6.1.80-RXN
xref: RHEA:22104
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.80
+property_value: skos:exactMatch RHEA:22104
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033856
@@ -203593,6 +210895,9 @@
xref: MetaCyc:PDXJ-RXN
xref: RHEA:15265
is_a: GO:0016769 ! transferase activity, transferring nitrogenous groups
+property_value: skos:exactMatch EC:2.6.99.2
+property_value: skos:exactMatch RHEA:15265
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033857
@@ -203607,6 +210912,8 @@
synonym: "PPIP5K" RELATED []
xref: MetaCyc:2.7.4.24-RXN
is_a: GO:0000829 ! diphosphoinositol pentakisphosphate kinase activity
+property_value: skos:broadMatch EC:2.7.4.24
+property_value: skos:exactMatch MetaCyc:2.7.4.24-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22677" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
@@ -203625,6 +210932,9 @@
xref: RHEA:12617
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.157
+property_value: skos:exactMatch RHEA:12617
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033859
@@ -203670,6 +210980,9 @@
xref: MetaCyc:RXN-12002
xref: RHEA:24400
is_a: GO:0050145 ! nucleoside monophosphate kinase activity
+property_value: skos:broadMatch EC:2.7.4.14
+property_value: skos:exactMatch EC:2.7.4.22
+property_value: skos:exactMatch RHEA:24400
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25991" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29533" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30557" xsd:anyURI
@@ -203688,6 +211001,9 @@
xref: RHEA:20109
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.4.23
+property_value: skos:exactMatch RHEA:20109
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033864
@@ -203737,6 +211053,8 @@
xref: EC:2.7.11.8
xref: MetaCyc:2.7.11.8-RXN
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:exactMatch EC:2.7.11.8
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033868
@@ -203770,6 +211088,9 @@
xref: MetaCyc:THIOL-SULFOTRANSFERASE-RXN
xref: RHEA:14637
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.16
+property_value: skos:exactMatch RHEA:14637
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033871
@@ -203809,6 +211130,9 @@
xref: MetaCyc:2.8.2.31-RXN
xref: RHEA:16997
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.31
+property_value: skos:exactMatch RHEA:16997
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033874
@@ -203820,6 +211144,9 @@
xref: MetaCyc:2.8.2.32-RXN
xref: RHEA:15477
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.32
+property_value: skos:exactMatch RHEA:15477
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033875
@@ -203843,6 +211170,9 @@
xref: MetaCyc:2.8.2.34-RXN
xref: RHEA:17689
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.34
+property_value: skos:exactMatch RHEA:17689
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033877
@@ -203859,6 +211189,9 @@
xref: RHEA:16469
xref: UM-BBD_reactionID:r0329
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.15
+property_value: skos:exactMatch RHEA:16469
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033878
@@ -203882,7 +211215,16 @@
synonym: "AAE" RELATED [EC:3.1.1.80]
synonym: "acetylajmalan esterase activity" RELATED [EC:3.1.1.80]
xref: EC:3.1.1.80
+xref: MetaCyc:RXN-8220
+xref: MetaCyc:RXN-8222
+xref: RHEA:22124
+xref: RHEA:23796
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.80
+property_value: skos:narrowMatch MetaCyc:RXN-8220
+property_value: skos:narrowMatch MetaCyc:RXN-8222
+property_value: skos:narrowMatch RHEA:22124
+property_value: skos:narrowMatch RHEA:23796
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -203896,6 +211238,9 @@
xref: MetaCyc:3.1.2.25-RXN
xref: RHEA:15337
is_a: GO:0016289 ! acyl-CoA hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.25
+property_value: skos:exactMatch RHEA:15337
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033881
@@ -203908,7 +211253,10 @@
xref: KEGG_REACTION:R07295
xref: RHEA:49436
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.25
+property_value: skos:exactMatch RHEA:49436
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22749" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033882
@@ -203923,6 +211271,9 @@
xref: MetaCyc:3.1.2.27-RXN
xref: RHEA:14541
is_a: GO:0016289 ! acyl-CoA hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.27
+property_value: skos:exactMatch RHEA:14541
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033883
@@ -203938,6 +211289,9 @@
xref: MetaCyc:3.1.3.74-RXN
xref: RHEA:20533
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.74
+property_value: skos:exactMatch RHEA:20533
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033884
@@ -203968,6 +211322,9 @@
xref: MetaCyc:3.1.3.76-RXN
xref: RHEA:16537
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.76
+property_value: skos:exactMatch RHEA:16537
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033886
@@ -203978,6 +211335,8 @@
xref: EC:3.1.6.7
xref: MetaCyc:3.1.6.7-RXN
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.7
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033887
@@ -203990,6 +211349,9 @@
xref: MetaCyc:CHONDRO-4-SULFATASE-RXN
xref: RHEA:11444
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.9
+property_value: skos:exactMatch RHEA:11444
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033888
@@ -204002,6 +211364,9 @@
xref: MetaCyc:CHONDRO-6-SULFATASE-RXN
xref: RHEA:10536
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.10
+property_value: skos:exactMatch RHEA:10536
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033889
@@ -204013,6 +211378,8 @@
xref: EC:3.1.6.15
xref: MetaCyc:3.1.6.15-RXN
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.15
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033890
@@ -204023,6 +211390,8 @@
xref: EC:3.1.13.5
xref: MetaCyc:3.1.13.5-RXN
is_a: GO:0016896 ! RNA exonuclease activity, producing 5'-phosphomonoesters
+property_value: skos:exactMatch EC:3.1.13.5
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033891
@@ -204036,6 +211405,8 @@
xref: EC:3.1.21.6
xref: MetaCyc:3.1.21.6-RXN
is_a: GO:0016888 ! DNA endonuclease activity, producing 5'-phosphomonoesters
+property_value: skos:exactMatch EC:3.1.21.6
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033892
@@ -204049,8 +211420,10 @@
xref: MetaCyc:3.1.25.1-RXN
is_a: GO:0004520 ! DNA endonuclease activity
is_a: GO:0016788 ! hydrolase activity, acting on ester bonds
+property_value: skos:exactMatch EC:3.1.25.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28395" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033893
@@ -204061,6 +211434,8 @@
xref: EC:3.1.26.6
xref: MetaCyc:3.1.26.6-RXN
is_a: GO:0016891 ! RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
+property_value: skos:exactMatch EC:3.1.26.6
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033894
@@ -204070,6 +211445,8 @@
xref: EC:3.1.26.7
xref: MetaCyc:3.1.26.7-RXN
is_a: GO:0016891 ! RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
+property_value: skos:exactMatch EC:3.1.26.7
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033895
@@ -204081,6 +211458,8 @@
synonym: "uracil-specific RNase activity" RELATED [EC:3.1.26.9]
xref: EC:3.1.26.9
is_a: GO:0016891 ! RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
+property_value: skos:exactMatch EC:3.1.26.9
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033896
@@ -204091,6 +211470,8 @@
xref: EC:3.1.26.10
xref: MetaCyc:3.1.26.10-RXN
is_a: GO:0016891 ! RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
+property_value: skos:exactMatch EC:3.1.26.10
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033897
@@ -204125,6 +211506,9 @@
xref: RHEA:68052
is_a: GO:0004521 ! RNA endonuclease activity
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
+property_value: skos:exactMatch EC:4.6.1.19
+property_value: skos:exactMatch MetaCyc:3.1.27.5-RXN
+property_value: skos:exactMatch RHEA:68052
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28225" xsd:anyURI
@@ -204156,8 +211540,11 @@
xref: MetaCyc:RXN-19928
is_a: GO:0004521 ! RNA endonuclease activity
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
+property_value: skos:broadMatch MetaCyc:3.1.27.3-RXN
+property_value: skos:exactMatch EC:4.6.1.20
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033900
@@ -204169,6 +211556,8 @@
xref: EC:3.1.27.7
xref: MetaCyc:3.1.27.7-RXN
is_a: GO:0016892 ! RNA endonuclease activity producing 3'-phosphomonoesters, hydrolytic mechanism
+property_value: skos:exactMatch EC:3.1.27.7
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033901
@@ -204179,6 +211568,8 @@
xref: EC:3.1.27.8
xref: MetaCyc:3.1.27.8-RXN
is_a: GO:0016892 ! RNA endonuclease activity producing 3'-phosphomonoesters, hydrolytic mechanism
+property_value: skos:exactMatch EC:3.1.27.8
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033902
@@ -204190,7 +211581,9 @@
xref: MetaCyc:3.1.27.10-RXN
is_a: GO:0004521 ! RNA endonuclease activity
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
+property_value: skos:exactMatch EC:4.6.1.23
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033903
@@ -204220,6 +211613,8 @@
xref: EC:3.2.1.11
xref: MetaCyc:3.2.1.11-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.11
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033905
@@ -204237,6 +211632,8 @@
xref: EC:3.2.1.32
xref: MetaCyc:3.2.1.32-RXN
is_a: GO:0097599 ! xylanase activity
+property_value: skos:exactMatch EC:3.2.1.32
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033906
@@ -204250,6 +211647,8 @@
xref: EC:3.2.1.36
xref: MetaCyc:3.2.1.36-RXN
is_a: GO:0046574 ! glucuronidase activity
+property_value: skos:exactMatch EC:3.2.1.36
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30698" xsd:anyURI
[Term]
@@ -204262,6 +211661,8 @@
xref: EC:3.2.1.38
xref: MetaCyc:3.2.1.38-RXN
is_a: GO:0015928 ! fucosidase activity
+property_value: skos:exactMatch EC:3.2.1.38
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30694" xsd:anyURI
[Term]
@@ -204273,6 +211674,8 @@
xref: EC:3.2.1.43
xref: MetaCyc:3.2.1.43-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.43
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033909
@@ -204283,6 +211686,8 @@
xref: EC:3.2.1.211
xref: MetaCyc:RXN-20949
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.211
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033910
@@ -204297,6 +211702,8 @@
xref: EC:3.2.1.60
xref: MetaCyc:3.2.1.60-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.60
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033911
@@ -204307,6 +211714,8 @@
xref: EC:3.2.1.61
xref: MetaCyc:3.2.1.61-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.61
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033912
@@ -204321,6 +211730,8 @@
xref: EC:3.2.1.64
xref: MetaCyc:3.2.1.64-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.64
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033913
@@ -204334,7 +211745,9 @@
xref: EC:3.2.1.71
xref: MetaCyc:3.2.1.71-RXN
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.71
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28262" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033914
@@ -204349,6 +211762,8 @@
xref: EC:3.2.1.72
xref: MetaCyc:3.2.1.72-RXN
is_a: GO:0097599 ! xylanase activity
+property_value: skos:exactMatch EC:3.2.1.72
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033915
@@ -204360,6 +211775,8 @@
xref: EC:3.2.1.77
xref: MetaCyc:3.2.1.77-RXN
is_a: GO:0004559 ! alpha-mannosidase activity
+property_value: skos:exactMatch EC:3.2.1.77
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033916
@@ -204373,6 +211790,8 @@
synonym: "agarose 4-glycanohydrolase activity" RELATED [EC:3.2.1.81]
xref: EC:3.2.1.81
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.81
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033917
@@ -204385,6 +211804,9 @@
xref: MetaCyc:3.2.1.82-RXN
xref: RHEA:56232
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.82
+property_value: skos:exactMatch RHEA:56232
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033918
@@ -204396,6 +211818,8 @@
xref: EC:3.2.1.83
xref: MetaCyc:3.2.1.83-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.83
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033919
@@ -204410,9 +211834,9 @@
xref: Reactome:R-HSA-548890 "Removal of the third glucose by glucosidase II and release from the chaperone"
xref: Reactome:R-HSA-9683663 "N-glycan trimming of Spike"
xref: Reactome:R-HSA-9694364 "N-glycan glucose trimming of Spike"
-xref: Reactome:R-HSA-9932352 "Glucosidase II removes glucose residue from Glu2Man9GlucNAc2-CDH1"
-xref: Reactome:R-HSA-9932913 "Glucosidase II removes glucose residue from Glu1Man9GlucNAc2-CDH1"
is_a: GO:0090599 ! alpha-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.84
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033920
@@ -204428,6 +211852,9 @@
xref: MetaCyc:6-PHOSPHO-BETA-GALACTOSIDASE-RXN
xref: RHEA:24568
is_a: GO:0015925 ! galactosidase activity
+property_value: skos:exactMatch EC:3.2.1.85
+property_value: skos:exactMatch RHEA:24568
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033921
@@ -204440,6 +211867,8 @@
xref: EC:3.2.1.87
xref: MetaCyc:3.2.1.87-RXN
is_a: GO:0015925 ! galactosidase activity
+property_value: skos:exactMatch EC:3.2.1.87
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033922
@@ -204453,6 +211882,8 @@
xref: EC:3.2.1.92
xref: MetaCyc:3.2.1.92-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.92
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033923
@@ -204467,6 +211898,8 @@
xref: EC:3.2.1.94
xref: MetaCyc:3.2.1.94-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.94
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033924
@@ -204478,6 +211911,8 @@
xref: EC:3.2.1.95
xref: MetaCyc:3.2.1.95-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.95
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033925
@@ -204505,6 +211940,8 @@
xref: MetaCyc:3.2.1.96-RXN
xref: Reactome:R-HSA-8853379 "ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5)"
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.96
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033926
@@ -204518,9 +211955,15 @@
xref: EC:3.2.1.97
xref: KEGG_REACTION:R04527
xref: MetaCyc:3.2.1.97-RXN
+xref: RHEA:30983
+xref: RHEA:54540
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:3.2.1.97
+property_value: skos:narrowMatch RHEA:30983
+property_value: skos:narrowMatch RHEA:54540
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25866" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033927
@@ -204534,6 +211977,8 @@
xref: EC:3.2.1.98
xref: MetaCyc:3.2.1.98-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.98
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033928
@@ -204547,6 +211992,8 @@
xref: EC:3.2.1.100
xref: MetaCyc:3.2.1.100-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.100
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033929
@@ -204558,6 +212005,8 @@
xref: EC:3.2.1.102
xref: MetaCyc:3.2.1.102-RXN
is_a: GO:0015925 ! galactosidase activity
+property_value: skos:exactMatch EC:3.2.1.102
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033930
@@ -204571,6 +212020,8 @@
xref: EC:3.2.1.103
xref: MetaCyc:3.2.1.103-RXN
is_a: GO:0015925 ! galactosidase activity
+property_value: skos:exactMatch EC:3.2.1.103
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033931
@@ -204581,6 +212032,8 @@
xref: EC:3.2.1.109
xref: MetaCyc:3.2.1.109-RXN
is_a: GO:0015929 ! hexosaminidase activity
+property_value: skos:exactMatch EC:3.2.1.109
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033932
@@ -204592,6 +212045,8 @@
xref: EC:3.2.1.111
xref: MetaCyc:3.2.1.111-RXN
is_a: GO:0004560 ! alpha-L-fucosidase activity
+property_value: skos:exactMatch EC:3.2.1.111
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033933
@@ -204604,7 +212059,9 @@
xref: EC:3.2.1.115
xref: MetaCyc:3.2.1.115-RXN
is_a: GO:0090599 ! alpha-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.115
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28262" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033934
@@ -204617,6 +212074,8 @@
xref: EC:3.2.1.116
xref: MetaCyc:3.2.1.116-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.116
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033935
@@ -204629,6 +212088,8 @@
xref: EC:3.2.1.120
xref: MetaCyc:3.2.1.120-RXN
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.120
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033936
@@ -204640,6 +212101,8 @@
xref: EC:3.2.1.121
xref: MetaCyc:3.2.1.121-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.121
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033937
@@ -204654,6 +212117,8 @@
xref: EC:3.2.1.124
xref: MetaCyc:3.2.1.124-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.124
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033938
@@ -204664,6 +212129,8 @@
xref: EC:3.2.1.127
xref: MetaCyc:3.2.1.127-RXN
is_a: GO:0004560 ! alpha-L-fucosidase activity
+property_value: skos:exactMatch EC:3.2.1.127
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033939
@@ -204676,6 +212143,8 @@
xref: EC:3.2.1.131
xref: MetaCyc:3.2.1.131-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.131
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033940
@@ -204692,6 +212161,8 @@
xref: EC:3.2.1.136
xref: MetaCyc:3.2.1.136-RXN
is_a: GO:0097599 ! xylanase activity
+property_value: skos:exactMatch EC:3.2.1.136
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033941
@@ -204703,6 +212174,8 @@
xref: EC:3.2.1.137
xref: MetaCyc:3.2.1.137-RXN
is_a: GO:0004559 ! alpha-mannosidase activity
+property_value: skos:exactMatch EC:3.2.1.137
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033942
@@ -204716,6 +212189,8 @@
xref: EC:3.2.1.141
xref: MetaCyc:3.2.1.141-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.141
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033943
@@ -204727,7 +212202,9 @@
xref: EC:3.2.1.145
xref: MetaCyc:3.2.1.145-RXN
is_a: GO:0004565 ! beta-galactosidase activity
+property_value: skos:exactMatch EC:3.2.1.145
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23375" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033944
@@ -204741,6 +212218,8 @@
xref: EC:3.2.1.146
xref: MetaCyc:3.2.1.146-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.146
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033945
@@ -204752,6 +212231,8 @@
xref: EC:3.2.1.150
xref: MetaCyc:3.2.1.150-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.150
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033946
@@ -204768,6 +212249,8 @@
xref: EC:3.2.1.151
xref: MetaCyc:3.2.1.151-RXN
is_a: GO:0052736 ! beta-glucanase activity
+property_value: skos:exactMatch EC:3.2.1.151
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033947
@@ -204778,6 +212261,8 @@
xref: EC:3.2.1.152
xref: MetaCyc:3.2.1.152-RXN
is_a: GO:0004567 ! beta-mannosidase activity
+property_value: skos:exactMatch EC:3.2.1.152
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033948
@@ -204794,6 +212279,8 @@
xref: EC:3.2.1.153
xref: MetaCyc:3.2.1.153-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.153
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033949
@@ -204806,6 +212293,8 @@
xref: EC:3.2.1.154
xref: MetaCyc:3.2.1.154-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.154
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033950
@@ -204817,6 +212306,8 @@
xref: EC:3.2.1.155
xref: MetaCyc:3.2.1.155-RXN
is_a: GO:0052736 ! beta-glucanase activity
+property_value: skos:exactMatch EC:3.2.1.155
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033951
@@ -204829,6 +212320,8 @@
xref: EC:3.2.1.156
xref: MetaCyc:3.2.1.156-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.156
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033952
@@ -204839,6 +212332,8 @@
xref: EC:3.2.1.157
xref: MetaCyc:3.2.1.157-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.157
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033953
@@ -204851,6 +212346,8 @@
xref: EC:3.2.1.158
xref: MetaCyc:3.2.1.158-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.158
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033954
@@ -204863,6 +212360,8 @@
xref: EC:3.2.1.159
xref: MetaCyc:3.2.1.159-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.159
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033955
@@ -204887,9 +212386,14 @@
synonym: "isoflavonoid 7-O-beta-apiosyl-glucoside beta-glucosidase activity" RELATED [EC:3.2.1.161]
synonym: "isoflavonoid-7-O-beta[D-apiosyl-(1->6)-beta-D-glucoside] disaccharidase activity" RELATED [EC:3.2.1.161]
xref: EC:3.2.1.161
+xref: MetaCyc:3.2.1.161-RXN
xref: MetaCyc:RXN-9156
xref: RHEA:21488
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.161
+property_value: skos:exactMatch MetaCyc:RXN-9156
+property_value: skos:exactMatch RHEA:21488
+property_value: skos:narrowMatch MetaCyc:3.2.1.161-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -204901,6 +212405,8 @@
xref: EC:3.2.1.162
xref: MetaCyc:3.2.1.162-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.162
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033958
@@ -204916,6 +212422,8 @@
xref: MetaCyc:3.2.2.15-RXN
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
is_a: GO:0140097 ! catalytic activity, acting on DNA
+property_value: skos:exactMatch EC:3.2.2.15
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033959
@@ -204933,6 +212441,8 @@
xref: MetaCyc:3.2.2.17-RXN
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
is_a: GO:0140097 ! catalytic activity, acting on DNA
+property_value: skos:exactMatch EC:3.2.2.17
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033960
@@ -204949,6 +212459,9 @@
xref: MetaCyc:RXN-7597
xref: RHEA:10880
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.2.25
+property_value: skos:exactMatch RHEA:10880
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033961
@@ -204972,7 +212485,10 @@
xref: Reactome:R-HSA-5694077 "EPHX1 hydrates BaP4,5O to BaP4,5-DHD"
xref: RHEA:23900
is_a: GO:0004301 ! epoxide hydrolase activity
+property_value: skos:exactMatch EC:3.3.2.9
+property_value: skos:exactMatch RHEA:23900
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27074" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033962
@@ -204994,7 +212510,16 @@
synonym: "ChEH" RELATED [EC:3.3.2.11]
synonym: "cholesterol-epoxide hydrolase activity" RELATED [EC:3.3.2.11]
xref: EC:3.3.2.11
+xref: MetaCyc:RXN-8650
+xref: MetaCyc:RXN-8651
+xref: RHEA:11964
+xref: RHEA:15113
is_a: GO:0016803 ! ether hydrolase activity
+property_value: skos:exactMatch EC:3.3.2.11
+property_value: skos:narrowMatch MetaCyc:RXN-8650
+property_value: skos:narrowMatch MetaCyc:RXN-8651
+property_value: skos:narrowMatch RHEA:11964
+property_value: skos:narrowMatch RHEA:15113
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -205007,6 +212532,8 @@
xref: EC:3.5.1.69
xref: MetaCyc:3.5.1.69-RXN
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.69
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033965
@@ -205018,17 +212545,24 @@
xref: EC:3.5.1.70
xref: MetaCyc:3.5.1.70-RXN
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.70
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033966
name: N-substituted formamide deformylase activity
namespace: molecular_function
-def: "Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine." [EC:3.5.1.91]
+def: "Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine." [RHEA:12096]
synonym: "N-benzylformamide amidohydrolase activity" RELATED [EC:3.5.1.91]
synonym: "NfdA" RELATED [EC:3.5.1.91]
+xref: EC:3.5.1.91
xref: MetaCyc:3.5.1.91-RXN
xref: RHEA:12096
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.91
+property_value: skos:exactMatch MetaCyc:3.5.1.91-RXN
+property_value: skos:exactMatch RHEA:12096
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0033967
@@ -205060,6 +212594,9 @@
xref: MetaCyc:3.5.1.93-RXN
xref: RHEA:23508
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.93
+property_value: skos:exactMatch RHEA:23508
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033969
@@ -205075,6 +212612,9 @@
xref: MetaCyc:RXN0-3942
xref: RHEA:19737
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.94
+property_value: skos:exactMatch RHEA:19737
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033970
@@ -205088,6 +212628,9 @@
xref: MetaCyc:3.5.1.95-RXN
xref: RHEA:17361
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.95
+property_value: skos:exactMatch RHEA:17361
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033971
@@ -205102,6 +212645,9 @@
xref: MetaCyc:3.5.2.17-RXN
xref: RHEA:23736
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.17
+property_value: skos:exactMatch RHEA:23736
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033972
@@ -205116,6 +212662,9 @@
xref: MetaCyc:3.5.3.22-RXN
xref: RHEA:17001
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.22
+property_value: skos:exactMatch RHEA:17001
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033973
@@ -205129,6 +212678,9 @@
xref: RHEA:19205
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.30
+property_value: skos:exactMatch RHEA:19205
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033974
@@ -205139,6 +212691,8 @@
xref: EC:3.6.1.24
xref: MetaCyc:3.6.1.24-RXN
is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
+property_value: skos:exactMatch EC:3.6.1.24
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033975
@@ -205153,7 +212707,10 @@
xref: EC:3.8.1.9
xref: MetaCyc:RXN-6264
xref: RHEA:22188
-is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds
+is_a: GO:0019120 ! hydrolase activity, acting on halide bonds, in C-halide compounds
+property_value: skos:exactMatch EC:3.8.1.9
+property_value: skos:exactMatch RHEA:22188
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033976
@@ -205168,7 +212725,9 @@
synonym: "DL-DEXi" RELATED []
xref: EC:3.8.1.10
xref: MetaCyc:2-HALOACID-DEHALOGENASE-RXN
-is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds
+is_a: GO:0019120 ! hydrolase activity, acting on halide bonds, in C-halide compounds
+property_value: skos:exactMatch EC:3.8.1.10
+property_value: skos:exactMatch MetaCyc:2-HALOACID-DEHALOGENASE-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28188" xsd:anyURI
[Term]
@@ -205183,7 +212742,10 @@
xref: EC:3.8.1.11
xref: MetaCyc:3.8.1.11-RXN
xref: RHEA:12072
-is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds
+is_a: GO:0019120 ! hydrolase activity, acting on halide bonds, in C-halide compounds
+property_value: skos:exactMatch EC:3.8.1.11
+property_value: skos:exactMatch RHEA:12072
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033978
@@ -205195,7 +212757,10 @@
xref: KEGG_REACTION:R08200
xref: MetaCyc:3.11.1.3-RXN
xref: RHEA:16673
-is_a: GO:0016827 ! hydrolase activity, acting on acid carbon-phosphorus bonds
+is_a: GO:0016827 ! hydrolase activity, acting on carbon-phosphorus bonds
+property_value: skos:exactMatch EC:3.11.1.3
+property_value: skos:exactMatch RHEA:16673
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033979
@@ -205220,6 +212785,9 @@
xref: MetaCyc:4.1.1.82-RXN
xref: RHEA:20768
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.82
+property_value: skos:exactMatch RHEA:20768
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033981
@@ -205239,6 +212807,9 @@
xref: MetaCyc:4.1.1.84-RXN
xref: RHEA:18441
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.84
+property_value: skos:exactMatch RHEA:18441
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033982
@@ -205257,6 +212828,9 @@
xref: MetaCyc:RXN0-705
xref: RHEA:14353
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.85
+property_value: skos:exactMatch RHEA:14353
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033983
@@ -205272,6 +212846,9 @@
xref: MetaCyc:4.1.1.86-RXN
xref: RHEA:15689
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.86
+property_value: skos:exactMatch RHEA:15689
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033984
@@ -205295,6 +212872,9 @@
xref: MetaCyc:RXN0-2381
xref: RHEA:14081
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.8
+property_value: skos:exactMatch RHEA:14081
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033985
@@ -205320,7 +212900,12 @@
synonym: "2,7,4'-trihydroxyisoflavanone hydro-lyase activity" RELATED [EC:4.2.1.105]
xref: EC:4.2.1.105
xref: MetaCyc:RXN-3284
+xref: RHEA:16445
+xref: RHEA:36803
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.105
+property_value: skos:narrowMatch RHEA:16445
+property_value: skos:narrowMatch RHEA:36803
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
[Term]
@@ -205336,7 +212921,10 @@
xref: MetaCyc:BA7DEHYDRA-RXN
xref: RHEA:10436
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.106
+property_value: skos:exactMatch RHEA:10436
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22749" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033989
@@ -205353,6 +212941,9 @@
xref: Reactome:R-HSA-193535 "25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA"
xref: RHEA:18933
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.107
+property_value: skos:exactMatch RHEA:18933
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033990
@@ -205370,6 +212961,9 @@
xref: MetaCyc:R103-RXN
xref: RHEA:17281
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.108
+property_value: skos:exactMatch RHEA:17281
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033991
@@ -205384,6 +212978,9 @@
xref: MetaCyc:RXN-14306
xref: RHEA:12100
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.110
+property_value: skos:exactMatch RHEA:12100
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033992
@@ -205401,6 +212998,9 @@
xref: MetaCyc:4.2.1.111-RXN
xref: RHEA:15725
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.111
+property_value: skos:exactMatch RHEA:15725
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033993
@@ -205418,6 +213018,8 @@
xref: EC:4.2.2.14
xref: MetaCyc:4.2.2.14-RXN
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.14
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033995
@@ -205431,6 +213033,8 @@
xref: EC:4.2.2.15
xref: MetaCyc:4.2.2.15-RXN
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.15
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033996
@@ -205443,6 +213047,8 @@
xref: EC:4.2.2.16
xref: MetaCyc:4.2.2.16-RXN
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.16
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033997
@@ -205457,6 +213063,8 @@
xref: EC:4.2.2.17
xref: MetaCyc:4.2.2.17-RXN
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.17
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033998
@@ -205474,6 +213082,8 @@
xref: EC:4.2.2.18
xref: MetaCyc:4.2.2.18-RXN
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.18
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0033999
@@ -205486,7 +213096,10 @@
synonym: "dermatan sulfate lyase activity" EXACT []
xref: EC:4.2.2.19
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:broadMatch MetaCyc:4.2.2.19-RXN
+property_value: skos:exactMatch EC:4.2.2.19
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034000
@@ -205502,7 +213115,14 @@
synonym: "ChS ABC lyase activity" BROAD [EC:4.2.2.20]
synonym: "ChS ABC lyase I activity" RELATED [EC:4.2.2.20]
xref: EC:4.2.2.20
+xref: MetaCyc:4.2.2.19-RXN
+xref: MetaCyc:4.2.2.5-RXN
+xref: MetaCyc:RXN-11572
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.20
+property_value: skos:narrowMatch MetaCyc:4.2.2.19-RXN
+property_value: skos:narrowMatch MetaCyc:4.2.2.5-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-11572
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26012" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -205523,6 +213143,8 @@
xref: EC:4.2.2.21
xref: MetaCyc:4.2.2.21-RXN
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.21
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034002
@@ -205537,6 +213159,9 @@
xref: MetaCyc:4.2.3.20-RXN
xref: RHEA:10940
is_a: GO:0010333 ! terpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.20
+property_value: skos:exactMatch RHEA:10940
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034003
@@ -205553,6 +213178,9 @@
xref: MetaCyc:RXN-4823
xref: RHEA:10340
is_a: GO:0010334 ! sesquiterpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.21
+property_value: skos:exactMatch RHEA:10340
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034004
@@ -205561,8 +213189,14 @@
def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate." [EC:4.2.3.22]
synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol-forming] activity" RELATED [EC:4.2.3.22]
xref: EC:4.2.3.22
+xref: MetaCyc:RXN-8648
xref: RHEA:22436
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:broadMatch KEGG_REACTION:R07647
+property_value: skos:exactMatch EC:4.2.3.22
+property_value: skos:exactMatch RHEA:22436
+property_value: skos:narrowMatch MetaCyc:RXN-8648
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034005
@@ -205580,6 +213214,9 @@
xref: MetaCyc:RXN-11527
xref: RHEA:12516
is_a: GO:0010334 ! sesquiterpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.23
+property_value: skos:exactMatch RHEA:12516
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034006
@@ -205593,6 +213230,9 @@
xref: MetaCyc:RXN-8046
xref: RHEA:18325
is_a: GO:0010334 ! sesquiterpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.24
+property_value: skos:exactMatch RHEA:18325
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034007
@@ -205607,6 +213247,9 @@
xref: MetaCyc:4.2.3.25-RXN
xref: RHEA:24116
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.25
+property_value: skos:exactMatch RHEA:24116
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034008
@@ -205621,6 +213264,9 @@
xref: MetaCyc:4.2.3.26-RXN
xref: RHEA:15809
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.26
+property_value: skos:exactMatch RHEA:15809
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034009
@@ -205635,6 +213281,8 @@
xref: MetaCyc:4.2.3.27-RXN
xref: RHEA:13369
is_a: GO:0010333 ! terpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.27
+property_value: skos:exactMatch RHEA:13369
[Term]
id: GO:0034010
@@ -205650,6 +213298,9 @@
xref: MetaCyc:RXN-11691
xref: RHEA:21428
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.24
+property_value: skos:exactMatch RHEA:21428
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034011
@@ -205664,6 +213315,9 @@
xref: MetaCyc:4.4.1.25-RXN
xref: RHEA:13441
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.25
+property_value: skos:exactMatch RHEA:13441
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034012
@@ -205677,6 +213331,9 @@
xref: RHEA:13729
is_a: GO:0009975 ! cyclase activity
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
+property_value: skos:exactMatch EC:4.6.1.15
+property_value: skos:exactMatch RHEA:13729
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034013
@@ -205688,7 +213345,10 @@
xref: MetaCyc:4.99.1.5-RXN
xref: RHEA:11316
is_a: GO:0141122 ! nitrogen-oxygen lyase activity
+property_value: skos:exactMatch EC:4.8.1.2
+property_value: skos:exactMatch RHEA:11316
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24927" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034014
@@ -205712,6 +213372,9 @@
xref: MetaCyc:LXULRU5P-RXN
xref: RHEA:18497
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.22
+property_value: skos:exactMatch RHEA:18497
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034016
@@ -205728,6 +213391,9 @@
xref: MetaCyc:5.3.3.13-RXN
xref: RHEA:14889
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.13
+property_value: skos:exactMatch RHEA:14889
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034017
@@ -205746,6 +213412,9 @@
xref: MetaCyc:5.3.3.14-RXN
xref: RHEA:23568
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.14
+property_value: skos:exactMatch RHEA:23568
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034018
@@ -205763,6 +213432,9 @@
xref: MetaCyc:5.3.3.15-RXN
xref: RHEA:22568
is_a: GO:0016862 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups
+property_value: skos:exactMatch EC:5.3.2.7
+property_value: skos:exactMatch RHEA:22568
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034019
@@ -205787,6 +213459,9 @@
xref: MetaCyc:RXN1F-155
xref: RHEA:10128
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:exactMatch EC:5.3.99.9
+property_value: skos:exactMatch RHEA:10128
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034021
@@ -205811,6 +213486,9 @@
xref: RHEA:20577
xref: UM-BBD_enzymeID:r1496
is_a: GO:0050486 ! intramolecular hydroxytransferase activity
+property_value: skos:exactMatch EC:5.4.4.3
+property_value: skos:exactMatch RHEA:20577
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034023
@@ -205826,6 +213504,9 @@
xref: MetaCyc:RXN0-743
xref: RHEA:13193
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.18
+property_value: skos:exactMatch RHEA:13193
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034024
@@ -205840,6 +213521,9 @@
xref: MetaCyc:RXN0-3901
xref: RHEA:13633
is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity
+property_value: skos:exactMatch EC:6.3.1.11
+property_value: skos:exactMatch RHEA:13633
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034025
@@ -205854,6 +213538,9 @@
xref: MetaCyc:6.3.1.12-RXN
xref: RHEA:10752
is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity
+property_value: skos:exactMatch EC:6.3.1.12
+property_value: skos:exactMatch RHEA:10752
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034026
@@ -205868,6 +213555,9 @@
xref: MetaCyc:RXN-16296
xref: RHEA:44332
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.49
+property_value: skos:exactMatch RHEA:44332
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034027
@@ -205882,6 +213572,9 @@
xref: MetaCyc:6.3.3.4-RXN
xref: RHEA:23620
is_a: GO:0016882 ! cyclo-ligase activity
+property_value: skos:exactMatch EC:6.3.3.4
+property_value: skos:exactMatch RHEA:23620
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034028
@@ -205897,6 +213590,9 @@
xref: MetaCyc:RXN0-742
xref: RHEA:19317
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.18
+property_value: skos:exactMatch RHEA:19317
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034029
@@ -205912,6 +213608,9 @@
xref: MetaCyc:RXN-8457
xref: RHEA:20425
is_a: GO:0016885 ! ligase activity, forming carbon-carbon bonds
+property_value: skos:exactMatch EC:6.4.1.7
+property_value: skos:exactMatch RHEA:20425
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034030
@@ -206019,6 +213718,9 @@
xref: Reactome:R-HSA-204647 "DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine"
xref: RHEA:33299
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.46
+property_value: skos:exactMatch RHEA:33299
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034039
@@ -206266,6 +213968,7 @@
is_a: GO:0016779 ! nucleotidyltransferase activity
is_a: GO:0140097 ! catalytic activity, acting on DNA
relationship: part_of GO:0071897 ! DNA biosynthetic process
+property_value: skos:exactMatch RHEA:22508
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28442" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30036" xsd:anyURI
@@ -206279,6 +213982,7 @@
xref: Reactome:R-HSA-6786881 "TRNT1 polymerizes CCA at the 3' end of pre-tRNA"
xref: RHEA:21248
is_a: GO:0097747 ! RNA polymerase activity
+property_value: skos:exactMatch RHEA:21248
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -206361,9 +214065,13 @@
def: "Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside." [GOC:cb, GOC:mah]
synonym: "aminoglycoside kinase activity" EXACT []
xref: EC:2.7.1.190
+xref: RHEA:48872
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.190
+property_value: skos:narrowMatch RHEA:48872
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21631" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034072
@@ -206383,16 +214091,23 @@
xref: EC:4.2.1.123
xref: RHEA:30675
is_a: GO:0034072 ! squalene cyclase activity
+property_value: skos:exactMatch EC:4.2.1.123
+property_value: skos:exactMatch RHEA:30675
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
id: GO:0034074
name: marneral synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: oxidosqualene = marneral." [GOC:cb, PMID:16425307, PMID:18033581]
+def: "Catalysis of the reaction: (S)-2,3-epoxysqualene = marneral." [PMID:16425307, PMID:18033581, RHEA:31875]
+xref: EC:5.4.99.53
xref: MetaCyc:RXN-9664
xref: RHEA:31875
is_a: GO:0031559 ! oxidosqualene cyclase activity
+property_value: skos:exactMatch EC:5.4.99.53
+property_value: skos:exactMatch MetaCyc:RXN-9664
+property_value: skos:exactMatch RHEA:31875
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0034075
@@ -206403,13 +214118,21 @@
xref: MetaCyc:RXN-9684
xref: RHEA:31035
is_a: GO:0031559 ! oxidosqualene cyclase activity
+property_value: skos:exactMatch EC:4.2.1.124
+property_value: skos:exactMatch RHEA:31035
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034076
name: cucurbitadienol synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: oxidosqualene = cucurbitadienol." [GOC:cb, PMID:18033581]
+def: "Catalysis of the reaction: (S)-2,3-epoxysqualene = cucurbitadienol." [PMID:18033581, RHEA:30999]
+xref: EC:5.4.99.33
+xref: RHEA:30999
is_a: GO:0031559 ! oxidosqualene cyclase activity
+property_value: skos:exactMatch EC:5.4.99.33
+property_value: skos:exactMatch RHEA:30999
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0034077
@@ -206441,7 +214164,7 @@
id: GO:0034079
name: butanediol biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3." [GOC:mah, ISBN:0911910123, MetaCyc:P125-PWY]
+def: "The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol." [GOC:mah, MetaCyc:P125-PWY]
synonym: "butanediol anabolism" EXACT []
synonym: "butanediol biosynthesis" EXACT []
synonym: "butanediol fermentation" EXACT []
@@ -207832,7 +215555,10 @@
xref: MetaCyc:RXN0-4361
xref: RHEA:28518
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.82
+property_value: skos:exactMatch RHEA:28518
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27990" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034201
@@ -207858,6 +215584,7 @@
xref: Reactome:R-HSA-4570573 "Defective RFT1 does not flip the N-glycan precursor"
is_a: GO:0140328 ! floppase activity
relationship: part_of GO:0034203 ! glycolipid translocation
+property_value: skos:broadMatch RHEA:66132
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28721" xsd:anyURI
[Term]
@@ -208373,88 +216100,63 @@
[Term]
id: GO:0034248
-name: regulation of amide metabolic process
+name: obsolete regulation of amide metabolic process
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah]
-synonym: "regulation of amide metabolism" EXACT []
-synonym: "regulation of cellular amide metabolic process" EXACT []
-is_a: GO:0019222 ! regulation of metabolic process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0043603 ! amide metabolic process
-relationship: regulates GO:0043603 ! amide metabolic process
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31123" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0019222
[Term]
id: GO:0034249
-name: negative regulation of amide metabolic process
+name: obsolete negative regulation of amide metabolic process
namespace: biological_process
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah]
-synonym: "negative regulation of amide metabolism" EXACT []
-synonym: "negative regulation of cellular amide metabolic process" EXACT []
-is_a: GO:0009892 ! negative regulation of metabolic process
-is_a: GO:0034248 ! regulation of amide metabolic process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0043603 ! amide metabolic process
-relationship: negatively_regulates GO:0043603 ! amide metabolic process
+def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31123" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0009892
[Term]
id: GO:0034250
-name: positive regulation of amide metabolic process
+name: obsolete positive regulation of amide metabolic process
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah]
-synonym: "positive regulation of amide metabolism" EXACT []
-synonym: "positive regulation of cellular amide metabolic process" EXACT []
-is_a: GO:0009893 ! positive regulation of metabolic process
-is_a: GO:0034248 ! regulation of amide metabolic process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0043603 ! amide metabolic process
-relationship: positively_regulates GO:0043603 ! amide metabolic process
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31123" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0009893
[Term]
id: GO:0034251
-name: regulation of amide catabolic process
+name: obsolete regulation of amide catabolic process
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah]
-synonym: "regulation of amide breakdown" EXACT []
-synonym: "regulation of amide catabolism" EXACT []
-synonym: "regulation of amide degradation" EXACT []
-synonym: "regulation of cellular amide catabolic process" EXACT []
-is_a: GO:0009894 ! regulation of catabolic process
-is_a: GO:0034248 ! regulation of amide metabolic process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0043605 ! amide catabolic process
-relationship: regulates GO:0043605 ! amide catabolic process
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31123" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0009894
[Term]
id: GO:0034252
-name: negative regulation of amide catabolic process
+name: obsolete negative regulation of amide catabolic process
namespace: biological_process
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah]
-synonym: "negative regulation of amide breakdown" EXACT []
-synonym: "negative regulation of amide catabolism" EXACT []
-synonym: "negative regulation of amide degradation" RELATED []
-synonym: "negative regulation of cellular amide catabolic process" EXACT []
-is_a: GO:0009895 ! negative regulation of catabolic process
-is_a: GO:0034249 ! negative regulation of amide metabolic process
-is_a: GO:0034251 ! regulation of amide catabolic process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0043605 ! amide catabolic process
-relationship: negatively_regulates GO:0043605 ! amide catabolic process
+def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31123" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0009895
[Term]
id: GO:0034253
-name: positive regulation of amide catabolic process
+name: obsolete positive regulation of amide catabolic process
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah]
-synonym: "positive regulation of amide breakdown" EXACT []
-synonym: "positive regulation of amide catabolism" EXACT []
-synonym: "positive regulation of amide degradation" RELATED []
-synonym: "positive regulation of cellular amide catabolic process" EXACT []
-is_a: GO:0009896 ! positive regulation of catabolic process
-is_a: GO:0034250 ! positive regulation of amide metabolic process
-is_a: GO:0034251 ! regulation of amide catabolic process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0043605 ! amide catabolic process
-relationship: positively_regulates GO:0043605 ! amide catabolic process
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31123" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0009896
[Term]
id: GO:0034254
@@ -208464,7 +216166,7 @@
synonym: "regulation of urea breakdown" EXACT []
synonym: "regulation of urea catabolism" EXACT []
synonym: "regulation of urea degradation" EXACT []
-is_a: GO:0034251 ! regulation of amide catabolic process
+is_a: GO:0009894 ! regulation of catabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
is_a: GO:1903314 ! regulation of nitrogen cycle metabolic process
intersection_of: GO:0065007 ! biological regulation
@@ -208492,6 +216194,8 @@
xref: EC:1.1.1.294
xref: MetaCyc:RXN-7678
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.294
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034257
@@ -208711,6 +216415,9 @@
xref: MetaCyc:RXN-4881
xref: RHEA:25532
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.28
+property_value: skos:exactMatch RHEA:25532
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034278
@@ -208723,6 +216430,9 @@
xref: MetaCyc:RXN-4882
xref: RHEA:25552
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.33
+property_value: skos:exactMatch RHEA:25552
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034279
@@ -208735,6 +216445,9 @@
xref: MetaCyc:RXN-4883
xref: RHEA:25560
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.35
+property_value: skos:exactMatch RHEA:25560
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034280
@@ -208748,13 +216461,23 @@
xref: MetaCyc:RXN-4884
xref: RHEA:25536
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.29
+property_value: skos:exactMatch RHEA:25536
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034281
name: ent-isokaurene synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: ent-copalyl diphosphate = ent-isokaurene + diphosphate." [PMID:17141283]
+def: "Catalysis of the reaction: ent-copalyl diphosphate = ent-isokaurene + diphosphate." [PMID:17141283, RHEA:25759]
+xref: EC:4.2.3.103
+xref: MetaCyc:RXN-12593
+xref: RHEA:25759
is_a: GO:0010333 ! terpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.103
+property_value: skos:exactMatch MetaCyc:RXN-12593
+property_value: skos:exactMatch RHEA:25759
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0034282
@@ -208768,6 +216491,9 @@
xref: MetaCyc:RXN-7788
xref: RHEA:25540
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.30
+property_value: skos:exactMatch RHEA:25540
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034283
@@ -208784,6 +216510,9 @@
xref: MetaCyc:RXN-9291
xref: RHEA:25556
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.34
+property_value: skos:exactMatch RHEA:25556
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034284
@@ -209263,6 +216992,7 @@
synonym: "DNA gyrase activity" RELATED []
synonym: "DNA-gyrase activity" RELATED []
is_a: GO:0003918 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
+property_value: skos:broadMatch EC:5.6.2.2
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/15575" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -209498,8 +217228,11 @@
synonym: "'de novo' NAD biosynthetic process from tryptophan" BROAD []
synonym: "de novo NAD biosynthetic process from tryptophan" RELATED []
xref: MetaCyc:NADSYN-PWY
+xref: MetaCyc:PWY-5653
is_a: GO:0006568 ! L-tryptophan metabolic process
is_a: GO:0009435 ! NAD+ biosynthetic process
+property_value: skos:exactMatch MetaCyc:NADSYN-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-5653
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29050" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29666" xsd:anyURI
@@ -209511,9 +217244,21 @@
synonym: "NAD biosynthetic process via the salvage pathway" EXACT []
synonym: "NAD salvage" EXACT []
synonym: "NAD salvage pathway" EXACT []
+xref: MetaCyc:NAD-BIOSYNTHESIS-III
+xref: MetaCyc:PWY-5381
+xref: MetaCyc:PWY-7761
+xref: MetaCyc:PWY-8511
+xref: MetaCyc:PWY3O-4107
+xref: MetaCyc:PYRIDNUCSAL-PWY
is_a: GO:0009435 ! NAD+ biosynthetic process
is_a: GO:0019365 ! pyridine nucleotide salvage
is_a: GO:0032261 ! purine nucleotide salvage
+property_value: skos:narrowMatch MetaCyc:NAD-BIOSYNTHESIS-III
+property_value: skos:narrowMatch MetaCyc:PWY-5381
+property_value: skos:narrowMatch MetaCyc:PWY-7761
+property_value: skos:narrowMatch MetaCyc:PWY-8511
+property_value: skos:narrowMatch MetaCyc:PWY3O-4107
+property_value: skos:narrowMatch MetaCyc:PYRIDNUCSAL-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21577" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29050" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29666" xsd:anyURI
@@ -209840,9 +217585,10 @@
synonym: "gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase activity" RELATED [EC:2.6.1.19]
xref: EC:2.6.1.19
xref: MetaCyc:GABATRANSAM-RXN
-xref: Reactome:R-HSA-916855 "PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA"
xref: RHEA:23352
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.19
+property_value: skos:exactMatch RHEA:23352
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
[Term]
@@ -209853,7 +217599,12 @@
synonym: "gamma-aminobutyric acid pyruvate transaminase activity" RELATED [EC:2.6.1.96]
xref: EC:2.6.1.96
xref: MetaCyc:RXN-6902
+xref: RHEA:32263
+xref: RHEA:32267
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.96
+property_value: skos:narrowMatch RHEA:32263
+property_value: skos:narrowMatch RHEA:32267
[Term]
id: GO:0034388
@@ -210247,6 +217998,9 @@
xref: MetaCyc:RXN-11102
xref: RHEA:27381
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.80
+property_value: skos:exactMatch RHEA:27381
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034418
@@ -210388,7 +218142,9 @@
synonym: "diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase activity" EXACT []
xref: RHEA:32047
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch RHEA:32047
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034432
@@ -210631,6 +218387,7 @@
xref: EC:5.6.2.6
xref: Reactome:R-HSA-9836927 "SUPV3L1 unwinds double-stranded mitochondiral RNA"
is_a: GO:0003724 ! RNA helicase activity
+property_value: skos:exactMatch EC:5.6.2.6
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21612" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -210800,25 +218557,35 @@
id: GO:0034479
name: phosphatidylglycerol phospholipase C activity
namespace: molecular_function
-def: "Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate." [GOC:mah, PMID:18434318]
-is_a: GO:0004629 ! phospholipase C activity
+def: "Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = sn-glycerol 3-phosphate + a 1,2-diacyl-sn-glycerol + H+." [PMID:18434318, RHEA:32927]
+synonym: "phosphatidylglycerol phospholipase C-type activity" EXACT []
+xref: RHEA:32927
+is_a: GO:0004629 ! C-type glycerophospholipase activity
+property_value: skos:exactMatch RHEA:32927
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30258" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30949" xsd:anyURI
[Term]
id: GO:0034480
name: phosphatidylcholine phospholipase C activity
namespace: molecular_function
-def: "Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycerol + H+ + phosphocholine." [GOC:mah, RHEA:10604]
+def: "Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycerol + H+ + phosphocholine." [RHEA:10604]
synonym: "Clostridium oedematiens beta- and gamma-toxins activity" NARROW [EC:3.1.4.3]
synonym: "Clostridium welchii alpha-toxin activity" NARROW [EC:3.1.4.3]
synonym: "heat-labile hemolysin" NARROW [EC:3.1.4.3]
synonym: "lipophosphodiesterase I activity" RELATED [EC:3.1.4.3]
synonym: "phosphatidylcholine cholinephosphohydrolase activity" RELATED []
+synonym: "phosphatidylcholine phospholipase C-type activity" EXACT []
synonym: "phospholipase C, acting on phosphatidylcholine" EXACT []
xref: EC:3.1.4.3
xref: MetaCyc:PHOSPHOLIPASE-C-RXN
xref: Reactome:R-HSA-9680388 "CSF1R-associated PLCG2 hydrolyzes phosphatidylcholine"
xref: RHEA:10604
-is_a: GO:0004629 ! phospholipase C activity
+is_a: GO:0004629 ! C-type glycerophospholipase activity
+property_value: skos:exactMatch EC:3.1.4.3
+property_value: skos:exactMatch RHEA:10604
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30949" xsd:anyURI
[Term]
id: GO:0034481
@@ -210826,6 +218593,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate." [GOC:curators]
is_a: GO:0050698 ! proteoglycan sulfotransferase activity
+property_value: skos:broadMatch EC:2.8.2.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28243" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28380" xsd:anyURI
@@ -210837,7 +218605,6 @@
synonym: "chondroitin 2-O-sulfotransferase activity" EXACT []
synonym: "chondroitin 2-O-sulphotransferase activity" EXACT []
xref: MetaCyc:RXN-11560
-xref: Reactome:R-HSA-9941305 "UST transfers sulfate to (2-)GlcA-GalNAc-6-sulfate"
is_a: GO:0034481 ! chondroitin sulfotransferase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28380" xsd:anyURI
@@ -210847,6 +218614,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate." [GOC:mah]
is_a: GO:0050698 ! proteoglycan sulfotransferase activity
+property_value: skos:broadMatch EC:2.8.2.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28380" xsd:anyURI
[Term]
@@ -210871,7 +218639,10 @@
xref: RHEA:25528
is_a: GO:0034594 ! phosphatidylinositol trisphosphate phosphatase activity
is_a: GO:0034595 ! phosphatidylinositol phosphate 5-phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.86
+property_value: skos:exactMatch RHEA:25528
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25279" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034486
@@ -211391,7 +219162,10 @@
xref: EC:3.7.1.20
xref: RHEA:26168
xref: UM-BBD_reactionID:r0811
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.20
+property_value: skos:exactMatch RHEA:26168
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034546
@@ -211887,7 +219661,10 @@
xref: RHEA:25674
is_a: GO:0034596 ! phosphatidylinositol phosphate 4-phosphatase activity
is_a: GO:0106019 ! phosphatidylinositol-4,5-bisphosphate phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.78
+property_value: skos:exactMatch RHEA:25674
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24252" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034598
@@ -212007,6 +219784,8 @@
def: "OBSOLETE. Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates." [GOC:mah]
comment: This term was obsoleted because it corresponds to an assay.
synonym: "RNA oligonucleotidase activity" EXACT []
+xref: Reactome:R-HSA-9009950 "PDE12 cleaves 2'-5' oligoadenylates"
+xref: Reactome:R-HSA-9615042 "Viral 2',5'-PDE cleaves 2'-5' oligoadenylates"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
is_obsolete: true
@@ -212058,7 +219837,6 @@
synonym: "H4biopterin binding" EXACT []
synonym: "sapropterin binding" EXACT []
xref: Reactome:R-HSA-1497784 "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle"
-xref: Reactome:R-HSA-1497796 "BH2 binding can lead to eNOS uncoupling"
is_a: GO:0005488 ! binding
[Term]
@@ -212131,10 +219909,16 @@
synonym: "nicotinamide nucleotide biosynthetic process from aspartate" EXACT []
synonym: "nicotinamide nucleotide formation from aspartate" EXACT []
synonym: "nicotinamide nucleotide synthesis from aspartate" EXACT []
+xref: MetaCyc:PWY-8277
+xref: MetaCyc:PWY-8352
+xref: MetaCyc:PYRIDNUCSYN-PWY
is_a: GO:0006531 ! aspartate metabolic process
is_a: GO:0009435 ! NAD+ biosynthetic process
is_a: GO:0170033 ! L-amino acid metabolic process
is_a: GO:0170039 ! proteinogenic amino acid metabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-8277
+property_value: skos:narrowMatch MetaCyc:PWY-8352
+property_value: skos:narrowMatch MetaCyc:PYRIDNUCSYN-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23285" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29050" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29666" xsd:anyURI
@@ -212337,7 +220121,10 @@
xref: RHEA:60208
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0032453 ! histone H3K4 demethylase activity
+property_value: skos:exactMatch EC:1.14.11.67
+property_value: skos:exactMatch RHEA:60208
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21089" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
[Term]
@@ -212858,6 +220645,8 @@
xref: MetaCyc:RXN0-304
xref: RHEA:28426
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch RHEA:28426
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034701
@@ -213057,8 +220846,14 @@
namespace: molecular_function
def: "Catalysis of the cleavage of a gamma-linked glutamate bond." [EC:3.4.19.9, MEROPS_fam:C26]
synonym: "gamma-glutamyl hydrolase activity" RELATED [EC:3.4.19.9]
+xref: EC:3.4.19.9
+xref: MetaCyc:RXN-3741
+xref: RHEA:56784
is_a: GO:0008234 ! cysteine-type peptidase activity
is_a: GO:0008242 ! omega peptidase activity
+property_value: skos:narrowMatch EC:3.4.19.9
+property_value: skos:narrowMatch MetaCyc:RXN-3741
+property_value: skos:narrowMatch RHEA:56784
[Term]
id: GO:0034725
@@ -213177,7 +220972,9 @@
xref: Reactome:R-HSA-8876696 "SOAT1,2 transfer acyl group to CHOL forming CHEST"
xref: RHEA:17729
is_a: GO:0004772 ! sterol O-acyltransferase activity
+property_value: skos:exactMatch RHEA:17729
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034737
@@ -213204,6 +221001,7 @@
synonym: "histone H4K12 deacetylase activity" BROAD []
is_a: GO:0141051 ! histone H4K deacetylase activity
is_a: GO:0141221 ! histone deacetylase activity, hydrolytic mechanism
+property_value: skos:broadMatch EC:3.5.1.98
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29468" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -213569,6 +221367,9 @@
xref: MetaCyc:RXN-5109
xref: RHEA:32691
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.106
+property_value: skos:exactMatch RHEA:32691
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034769
@@ -213730,7 +221531,9 @@
xref: RHEA:52620
xref: UM-BBD_reactionID:r1033
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch RHEA:52620
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28064" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034785
@@ -213742,6 +221545,9 @@
xref: RHEA:35307
xref: UM-BBD_reactionID:r1034
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.172
+property_value: skos:exactMatch RHEA:35307
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034786
@@ -214172,6 +221978,8 @@
xref: MetaCyc:RXN-11970
xref: RHEA:34351
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.86
+property_value: skos:exactMatch RHEA:34351
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28287" xsd:anyURI
[Term]
@@ -214390,6 +222198,9 @@
xref: RHEA:32535
xref: UM-BBD_reactionID:r1281
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.132
+property_value: skos:exactMatch RHEA:32535
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034857
@@ -214562,6 +222373,9 @@
xref: RHEA:47148
xref: UM-BBD_reactionID:r1321
is_a: GO:0033695 ! oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.17.5.2
+property_value: skos:exactMatch RHEA:47148
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034876
@@ -214783,6 +222597,9 @@
xref: RHEA:31979
xref: UM-BBD_reactionID:r1407
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.148
+property_value: skos:exactMatch RHEA:31979
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034900
@@ -214874,6 +222691,9 @@
xref: RHEA:34223
xref: UM-BBD_reactionID:r1441
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.99.14
+property_value: skos:exactMatch RHEA:34223
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034910
@@ -215130,7 +222950,10 @@
xref: RHEA:30351
xref: UM-BBD_reactionID:r0968
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.130
+property_value: skos:exactMatch RHEA:30351
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28088" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034939
@@ -215158,6 +222981,8 @@
xref: EC:4.1.1.93
xref: UM-BBD_reactionID:r0970
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.93
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0034942
@@ -215507,6 +223332,8 @@
xref: Reactome:R-HSA-9854463 "SIRT3 deacetylates AcK-IDH2 dimer"
xref: RHEA:43636
is_a: GO:0141218 ! NAD-dependent protein lysine deacylase activity
+property_value: skos:exactMatch EC:2.3.1.286
+property_value: skos:exactMatch RHEA:43636
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22295" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27528" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28920" xsd:anyURI
@@ -215736,7 +223563,10 @@
xref: Reactome:R-HSA-8868072 "Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2"
xref: RHEA:18373
is_a: GO:0052742 ! phosphatidylinositol kinase activity
+property_value: skos:exactMatch EC:2.7.1.154
+property_value: skos:exactMatch RHEA:18373
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28336" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0035006
@@ -217222,6 +225052,7 @@
synonym: "histone-serine kinase activity (H3-S10 specific)" EXACT []
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0140996 ! histone H3 kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -217887,6 +225718,9 @@
xref: EC:2.1.1.321
xref: RHEA:48100
is_a: GO:0016274 ! protein-arginine N-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.321
+property_value: skos:exactMatch RHEA:48100
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0035242
@@ -217903,6 +225737,9 @@
xref: Reactome:R-HSA-9729283 "Nucleoprotein is methylated by PRMT1"
xref: RHEA:48096
is_a: GO:0016274 ! protein-arginine N-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.319
+property_value: skos:exactMatch RHEA:48096
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0035243
@@ -217921,6 +225758,9 @@
xref: RESID:AA0069
xref: RHEA:48108
is_a: GO:0016274 ! protein-arginine N-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.320
+property_value: skos:exactMatch RHEA:48108
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0035244
@@ -217936,7 +225776,10 @@
is_a: GO:0008169 ! C-methyltransferase activity
is_a: GO:0008276 ! protein methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.379
+property_value: skos:exactMatch RHEA:66028
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23704" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0035245
@@ -217971,9 +225814,10 @@
id: GO:0035248
name: alpha-1,4-N-acetylgalactosaminyltransferase activity
namespace: molecular_function
-def: "Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage." [PMID:15130086]
+def: "Catalysis of the reaction: an N-acetyl-beta-D-galactosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-beta-D-galactosaminyl derivative + UDP + H+." [PMID:15130086]
synonym: "alpha-1,4-GalNAc transferase activity" EXACT []
is_a: GO:0008376 ! acetylgalactosaminyltransferase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31147" xsd:anyURI
[Term]
id: GO:0035249
@@ -218006,8 +225850,9 @@
name: UDP-xylosyltransferase activity
namespace: molecular_function
def: "Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule." [PMID:30127001]
+xref: Reactome:R-HSA-5617138 "B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA"
xref: Reactome:R-HSA-6785668 "Defective LARGE does not transfer Xyl from UDP-Xyl to GlcA"
-xref: Reactome:R-HSA-9638090 "LARGE1,2 elongates matriglycan chain with Xyl"
+xref: Reactome:R-HSA-9638090 "B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA"
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0042285 ! xylosyltransferase activity
@@ -218141,7 +225986,13 @@
def: "A glycoprotein biosynthetic process starting with the covalent linkage of a mannose via an alpha-glycosidic bond to the oxygen atom of a serine or threonine side chain in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan." [PMID:35536928]
synonym: "protein amino acid O-linked mannosylation" EXACT [GOC:bf]
synonym: "protein O-linked mannosylation" RELATED []
+xref: MetaCyc:PWY-7921
+xref: MetaCyc:PWY-7922
+xref: MetaCyc:PWY-7979
is_a: GO:0006493 ! protein O-linked glycosylation
+property_value: skos:narrowMatch MetaCyc:PWY-7921
+property_value: skos:narrowMatch MetaCyc:PWY-7922
+property_value: skos:narrowMatch MetaCyc:PWY-7979
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30362" xsd:anyURI
@@ -218424,6 +226275,10 @@
xref: Reactome:R-HSA-1855179 "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol"
xref: RHEA:20313
is_a: GO:0120517 ! inositol pentakisphosphate kinase activity
+property_value: skos:exactMatch EC:2.7.1.158
+property_value: skos:exactMatch KEGG_REACTION:R05202
+property_value: skos:exactMatch MetaCyc:RXN-7163
+property_value: skos:exactMatch RHEA:20313
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
[Term]
@@ -218454,8 +226309,14 @@
namespace: molecular_function
def: "Catalysis of the hydroxylation of an ecdysteroid at carbon position 25." [PMID:15350618]
comment: Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2,22,25-trideoxyecdysone (3-beta,5-beta-ketodiol) to 2,22-dideoxyecdysone (3-beta,5-beta-ketotriol).
+xref: MetaCyc:RXN-14677
+xref: MetaCyc:RXN-14680
+xref: RHEA:82347
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:narrowMatch MetaCyc:RXN-14677
+property_value: skos:narrowMatch MetaCyc:RXN-14680
+property_value: skos:narrowMatch RHEA:82347
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29033" xsd:anyURI
[Term]
@@ -218662,13 +226523,14 @@
[Term]
id: GO:0035322
-name: mesenchymal cell migration involved in limb bud formation
+name: obsolete mesenchymal cell migration involved in limb bud formation
namespace: biological_process
-def: "The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud." [GOC:dgh]
-is_a: GO:0090497 ! mesenchymal cell migration
-intersection_of: GO:0090497 ! mesenchymal cell migration
-intersection_of: part_of GO:0060174 ! limb bud formation
-relationship: part_of GO:0090496 ! mesenchyme migration involved in limb bud formation
+def: "OBSOLETE. The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud." [GOC:dgh]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060174
+consider: GO:0090497
created_by: bf
creation_date: 2010-02-24T02:05:14Z
@@ -219221,7 +227083,6 @@
namespace: molecular_function
def: "Binding to a selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation." [GOC:imk, PMID:10760958]
synonym: "SECIS binding" EXACT []
-xref: Reactome:R-HSA-2408529 "Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome"
is_a: GO:0003729 ! mRNA binding
created_by: bf
creation_date: 2010-03-11T10:42:28Z
@@ -219600,6 +227461,7 @@
synonym: "histone-tyrosine kinase activity (H3-Y41 specific)" EXACT []
is_a: GO:0004713 ! protein tyrosine kinase activity
is_a: GO:0140996 ! histone H3 kinase activity
+property_value: skos:broadMatch RHEA:10596
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: bf
@@ -219617,6 +227479,7 @@
synonym: "histone-threonine kinase activity (H3-T11 specific)" EXACT []
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0140996 ! histone H3 kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: bf
@@ -219634,6 +227497,7 @@
synonym: "histone-threonine kinase activity (H3-T6 specific)" EXACT []
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0140996 ! histone H3 kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: bf
@@ -220026,6 +227890,9 @@
xref: RHEA:25621
is_a: GO:0009975 ! cyclase activity
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.16
+property_value: skos:exactMatch RHEA:25621
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2010-04-09T02:59:35Z
@@ -220115,7 +227982,10 @@
xref: MetaCyc:RXN1G-121
xref: RHEA:26176
is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity
+property_value: skos:exactMatch EC:6.3.1.13
+property_value: skos:exactMatch RHEA:26176
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2010-04-14T11:33:06Z
@@ -220129,6 +227999,9 @@
xref: MetaCyc:RXN1G-4
xref: RHEA:26172
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.189
+property_value: skos:exactMatch RHEA:26172
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2010-04-14T11:40:26Z
@@ -220306,6 +228179,8 @@
def: "Catalysis of the reaction: L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate." [PMID:18097099, PMID:20359483]
xref: RHEA:28803
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch RHEA:28803
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2010-04-16T02:05:41Z
@@ -220643,15 +228518,13 @@
[Term]
id: GO:0035492
-name: negative regulation of leukotriene production involved in inflammatory response
+name: obsolete negative regulation of leukotriene production involved in inflammatory response
namespace: biological_process
-def: "Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response." [GOC:bf]
-is_a: GO:0035490 ! regulation of leukotriene production involved in inflammatory response
-is_a: GO:0050728 ! negative regulation of inflammatory response
-is_a: GO:0051241 ! negative regulation of multicellular organismal process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0002540 ! leukotriene production involved in inflammatory response
-relationship: negatively_regulates GO:0002540 ! leukotriene production involved in inflammatory response
+def: "OBSOLETE. Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response." [GOC:bf]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0006954
created_by: bf
creation_date: 2010-04-26T10:50:55Z
@@ -220720,7 +228593,6 @@
synonym: "carnosine metabolism" EXACT []
is_a: GO:0006520 ! amino acid metabolic process
is_a: GO:0019752 ! carboxylic acid metabolic process
-is_a: GO:0043603 ! amide metabolic process
created_by: bf
creation_date: 2010-04-29T01:19:52Z
@@ -220735,7 +228607,6 @@
synonym: "carnosine synthesis" EXACT []
is_a: GO:0008652 ! amino acid biosynthetic process
is_a: GO:0035498 ! carnosine metabolic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0046394 ! carboxylic acid biosynthetic process
created_by: bf
creation_date: 2010-04-29T01:20:56Z
@@ -220940,7 +228811,10 @@
xref: RHEA:30299
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0035514 ! DNA demethylase activity
+property_value: skos:exactMatch EC:1.14.11.33
+property_value: skos:exactMatch RHEA:30299
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21159" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2010-04-30T02:38:16Z
@@ -221073,6 +228947,9 @@
xref: MetaCyc:RXN-8974
xref: RHEA:26438
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.298
+property_value: skos:exactMatch RHEA:26438
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2010-05-05T10:55:07Z
@@ -221106,7 +228983,10 @@
xref: Reactome:R-HSA-6809287 "NUDT12 hydrolyses NADH to NMNH"
xref: RHEA:48868
is_a: GO:0004551 ! dinucleotide phosphatase activity
+property_value: skos:broadMatch EC:3.6.1.22
+property_value: skos:exactMatch RHEA:48868
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19775" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2010-05-05T04:55:10Z
@@ -221196,6 +229076,9 @@
xref: Reactome:R-HSA-9750555 "NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP"
xref: RHEA:31575
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:exactMatch EC:3.6.1.55
+property_value: skos:exactMatch RHEA:31575
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2010-05-07T10:54:19Z
@@ -221425,6 +229308,9 @@
xref: EC:3.1.1.82
xref: RHEA:32483
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.82
+property_value: skos:exactMatch RHEA:32483
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2010-05-14T02:39:58Z
@@ -221602,8 +229488,10 @@
synonym: "histone H4-methyl-lysine-20 demethylase activity" EXACT []
synonym: "histone H4K20me demethylase activity" EXACT []
xref: Reactome:R-HSA-2172678 "PHF8 demethylates histone H4K20me1"
+xref: RHEA:67804
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0141058 ! histone H4 demethylase activity
+property_value: skos:narrowMatch RHEA:67804
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21089" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29636" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -221855,6 +229743,9 @@
xref: RHEA:26180
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0019213 ! deacetylase activity
+property_value: skos:exactMatch EC:3.5.1.103
+property_value: skos:exactMatch RHEA:26180
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2010-11-11T02:12:48Z
@@ -221881,6 +229772,8 @@
is_a: GO:0035596 ! methylthiotransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
relationship: part_of GO:0035600 ! tRNA methylthiolation
+property_value: skos:exactMatch EC:2.8.4.3
+property_value: skos:exactMatch RHEA:37067
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29839" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29840" xsd:anyURI
created_by: bf
@@ -221900,7 +229793,10 @@
is_a: GO:0035596 ! methylthiotransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
relationship: part_of GO:0035600 ! tRNA methylthiolation
+property_value: skos:exactMatch EC:2.8.4.5
+property_value: skos:exactMatch RHEA:37075
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29839" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2010-11-12T01:28:32Z
@@ -221993,8 +229889,12 @@
comment: This term should not be used to annotate the nitrosylating action of nitric oxide synthase (NOS) if the nitroso group is synthesized directly on the substrate.
synonym: "protein nitrosylase activity" RELATED [GOC:sp]
synonym: "S-nitrosylase activity" EXACT [PMID:20972426]
+xref: RHEA:66684
+xref: RHEA:67152
is_a: GO:0016769 ! transferase activity, transferring nitrogenous groups
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:narrowMatch RHEA:66684
+property_value: skos:narrowMatch RHEA:67152
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23262" xsd:anyURI
created_by: bf
creation_date: 2010-11-16T09:49:26Z
@@ -222109,12 +230009,14 @@
[Term]
id: GO:0035615
-name: clathrin adaptor activity
+name: clathrin-cargo adaptor activity
namespace: molecular_function
-def: "Bringing together a cargo protein with clathrin, responsible for the formation of endocytic vesicles." [GOC:BHF, PMID:15728179]
+def: "Bringing together a cargo protein with clathrin, responsible for the formation of endocytic vesicles." [GOC:BHF, PMID:15728179, PMID:29661000]
+synonym: "clathrin adaptor activity" EXACT []
synonym: "clathrin-associated adaptor activity" EXACT [PMID:15728179]
is_a: GO:0140312 ! cargo adaptor activity
relationship: has_part GO:0030276 ! clathrin binding
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31241" xsd:anyURI
created_by: bf
creation_date: 2010-12-01T11:17:57Z
@@ -222251,7 +230153,7 @@
def: "The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid." [GOC:bf, GOC:sart]
xref: Reactome:R-HSA-9845576 "Glycosphingolipid transport"
is_a: GO:0006869 ! lipid transport
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
created_by: bf
creation_date: 2010-12-10T10:02:16Z
@@ -222415,6 +230317,9 @@
synonym: "histone-H3R17 methyltransferase activity" EXACT []
is_a: GO:0016274 ! protein-arginine N-methyltransferase activity
is_a: GO:0140938 ! histone H3 methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.319
+property_value: skos:broadMatch EC:2.1.1.320
+property_value: skos:broadMatch RHEA:48108
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: bf
@@ -222765,7 +230670,7 @@
alt_id: GO:0015198
def: "Enables the transfer of oligopeptides from one side of a membrane to the other. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages." [GOC:vw, ISBN:0198506732]
synonym: "oligopeptide transporter activity" RELATED []
-is_a: GO:0042887 ! amide transmembrane transporter activity
+is_a: GO:0022857 ! transmembrane transporter activity
relationship: part_of GO:0035672 ! oligopeptide transmembrane transport
created_by: bf
creation_date: 2011-02-08T02:20:14Z
@@ -223629,13 +231534,15 @@
[Term]
id: GO:0035755
-name: cardiolipin hydrolase activity
+name: cardiolipin phospholipase D activity
namespace: molecular_function
-def: "Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol), releasing phosphatidic acid (PA)." [GOC:sp, PMID:17028579, PMID:21397848]
+def: "Catalysis of the reaction: a cardiolipin + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate + H(+)." [PMID:17028579, PMID:21397848, RHEA:44884]
+synonym: "cardiolipin hydrolase activity" BROAD []
xref: Reactome:R-HSA-8954398 "PLD6 dimer hydrolyses cardiolipin to PA and PG"
-is_a: GO:0004620 ! phospholipase activity
-is_a: GO:0008081 ! phosphoric diester hydrolase activity
+xref: RHEA:44884
+is_a: GO:0004630 ! D-type glycerophospholipase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21230" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31040" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/8492" xsd:anyURI
created_by: bf
creation_date: 2011-03-24T10:14:05Z
@@ -223738,13 +231645,14 @@
[Term]
id: GO:0035765
-name: motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation
+name: obsolete motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation
namespace: biological_process
-def: "The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve." [GOC:dgh, PMID:21262462]
-is_a: GO:0021535 ! cell migration in hindbrain
-intersection_of: GO:0021535 ! cell migration in hindbrain
-intersection_of: part_of GO:0035764 ! dorsal motor nucleus of vagus nerve formation
-relationship: part_of GO:0035764 ! dorsal motor nucleus of vagus nerve formation
+def: "OBSOLETE. The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve." [GOC:dgh, PMID:21262462]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0021535
+consider: GO:0035764
created_by: bf
creation_date: 2011-03-29T02:52:09Z
@@ -224119,11 +232027,18 @@
id: GO:0035797
name: tellurite methyltransferase activity
namespace: molecular_function
-def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to tellurite [TeO3(2-)]. Methylated derivatives of tellurite include Te(CH3)2 (dimethyltelluride) and Te2(CH3)2 (dimethylditelluride)." [GOC:bf, GOC:kad, PMID:11053398, PMID:21244361]
+def: "Catalysis of the reaction: tellurite + S-adenosyl-L-methionine = methanetellurite + S-adenosyl-L-homocysteine." [PMID:11053398, PMID:21244361, RHEA:34539]
synonym: "S-adenosyl-L-methionine-dependent tellurite methyltransferase activity" EXACT [GOC:bf]
synonym: "SAM-dependent tellurite methyltransferase activity" EXACT [GOC:bf]
synonym: "tellurite methylase activity" BROAD [GOC:bf]
+xref: EC:2.1.1.265
+xref: MetaCyc:RXN0-6576
+xref: RHEA:34539
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.265
+property_value: skos:exactMatch MetaCyc:RXN0-6576
+property_value: skos:exactMatch RHEA:34539
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: bf
creation_date: 2011-04-14T01:06:19Z
@@ -224136,8 +232051,11 @@
xref: EC:1.3.1.102
xref: RHEA:13737
is_a: GO:0032440 ! 2-alkenal reductase [NAD(P)H] activity
+property_value: skos:exactMatch EC:1.3.1.102
+property_value: skos:exactMatch RHEA:13737
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2011-04-14T01:11:07Z
@@ -224373,13 +232291,14 @@
[Term]
id: GO:0035817
-name: renal sodium ion absorption involved in negative regulation of renal sodium excretion
+name: obsolete renal sodium ion absorption involved in negative regulation of renal sodium excretion
namespace: biological_process
-def: "Any process where sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron, which contributes to decreasing the amount of sodium that is excreted in urine per unit time." [GOC:mtg_25march11, GOC:yaf]
-is_a: GO:0070294 ! renal sodium ion absorption
-intersection_of: GO:0070294 ! renal sodium ion absorption
-intersection_of: part_of GO:0035814 ! negative regulation of renal sodium excretion
-relationship: part_of GO:0035814 ! negative regulation of renal sodium excretion
+def: "OBSOLETE. Any process where sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron, which contributes to decreasing the amount of sodium that is excreted in urine per unit time." [GOC:mtg_25march11, GOC:yaf]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0035814
+consider: GO:0070294
created_by: bf
creation_date: 2011-04-20T01:40:11Z
@@ -225011,6 +232930,9 @@
xref: Reactome:R-HSA-2509838 "ITPA hydrolyses dITP to dIMP"
xref: RHEA:28342
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:broadMatch EC:3.6.1.66
+property_value: skos:exactMatch RHEA:28342
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2011-05-26T11:32:26Z
@@ -225181,10 +233103,16 @@
name: exochitinase activity
namespace: molecular_function
def: "Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain." [GOC:bf, GOC:kah, GOC:pde, PMID:11468293, PMID:16298970, PMID:21390509]
+xref: EC:3.2.1.200
+xref: EC:3.2.1.201
xref: MetaCyc:RXN-12309
xref: RHEA:50672
is_a: GO:0004568 ! chitinase activity
+property_value: skos:exactMatch RHEA:50672
+property_value: skos:narrowMatch EC:3.2.1.200
+property_value: skos:narrowMatch EC:3.2.1.201
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28722" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2011-06-08T11:13:58Z
@@ -225220,6 +233148,8 @@
xref: RHEA:47720
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch MetaCyc:RXN0-6708
+property_value: skos:exactMatch RHEA:47720
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
created_by: bf
creation_date: 2011-06-14T02:15:53Z
@@ -226374,6 +234304,7 @@
synonym: "histone kinase activity (H2A.x-S139 specific)" NARROW [GOC:bf, PMID:16061642]
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0141003 ! histone H2AX kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25034" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -226726,6 +234657,7 @@
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0008276 ! protein methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch RHEA:57452
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29860" xsd:anyURI
created_by: bf
creation_date: 2011-10-03T02:27:05Z
@@ -227274,6 +235206,8 @@
xref: RHEA:47672
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch RHEA:47672
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
created_by: bf
creation_date: 2011-12-12T01:29:21Z
@@ -227290,7 +235224,9 @@
xref: RHEA:47668
is_a: GO:0141218 ! NAD-dependent protein lysine deacylase activity
relationship: part_of GO:0036049 ! peptidyl-lysine desuccinylation
+property_value: skos:exactMatch RHEA:47668
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28920" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2011-12-12T01:33:51Z
@@ -228088,6 +236024,7 @@
synonym: "dsDNA-dependent ATP-dependent DNA helicase activity" EXACT [GOC:kmv]
synonym: "dsDNA-dependent ATPase activity" EXACT []
is_a: GO:0003678 ! DNA helicase activity
+property_value: skos:broadMatch EC:3.6.4.12
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: bf
creation_date: 2012-02-20T02:53:51Z
@@ -228198,6 +236135,8 @@
xref: RHEA:45312
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
relationship: part_of GO:0006693 ! prostaglandin metabolic process
+property_value: skos:exactMatch RHEA:45312
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
created_by: bf
creation_date: 2012-03-05T09:25:03Z
@@ -228214,7 +236153,9 @@
xref: RHEA:45316
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
relationship: part_of GO:0006693 ! prostaglandin metabolic process
+property_value: skos:exactMatch RHEA:45316
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-03-05T10:27:29Z
@@ -228242,6 +236183,8 @@
xref: Reactome:R-HSA-2161732 "TXB2 is converted to 11dh-TXB2 by TXDH"
xref: RHEA:52312
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:52312
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-03-05T11:05:09Z
@@ -228254,6 +236197,8 @@
xref: Reactome:R-HSA-2161613 "PGH2 is degraded to 12S-HHT and MDA by TBXAS1"
xref: RHEA:48644
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:48644
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-03-05T11:17:34Z
@@ -228317,7 +236262,10 @@
xref: RHEA:54256
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:1.14.11.79
+property_value: skos:exactMatch RHEA:54256
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27537" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-03-07T09:26:54Z
@@ -228329,10 +236277,16 @@
def: "Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2." [GOC:reh, PMID:12215170, RHEA:54260]
synonym: "hypoxia-inducible factor-asparagine oxygenase activity" NARROW []
synonym: "peptidyl-asparagine 3-dioxygenase activity" EXACT []
+xref: EC:1.14.11.30
+xref: MetaCyc:RXN-11321
xref: RHEA:54260
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch RHEA:54260
+property_value: skos:narrowMatch EC:1.14.11.30
+property_value: skos:narrowMatch MetaCyc:RXN-11321
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23829" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-03-07T09:27:44Z
@@ -228628,6 +236582,7 @@
namespace: molecular_function
def: "OBSOLETE. Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2." [GOC:mw, PMID:620805, PMID:7028108]
comment: The reason for obsoletion is that this term is equivalent to 4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity.
+xref: Reactome:R-HSA-2162195 "COQ4 decarboxylates MHDB"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29459" xsd:anyURI
is_obsolete: true
replaced_by: GO:0120539
@@ -228659,8 +236614,24 @@
name: thiamine salvage
namespace: biological_process
def: "A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis." [PMID:15150256, PMID:16952958]
+xref: MetaCyc:PWY-6896
+xref: MetaCyc:PWY-6897
+xref: MetaCyc:PWY-6898
+xref: MetaCyc:PWY-6899
+xref: MetaCyc:PWY-6910
+xref: MetaCyc:PWY-7356
+xref: MetaCyc:PWY-7357
+xref: MetaCyc:PWY-8457
is_a: GO:0008655 ! pyrimidine-containing compound salvage
is_a: GO:0009228 ! thiamine biosynthetic process
+property_value: skos:narrowMatch MetaCyc:PWY-6896
+property_value: skos:narrowMatch MetaCyc:PWY-6897
+property_value: skos:narrowMatch MetaCyc:PWY-6898
+property_value: skos:narrowMatch MetaCyc:PWY-6899
+property_value: skos:narrowMatch MetaCyc:PWY-6910
+property_value: skos:narrowMatch MetaCyc:PWY-7356
+property_value: skos:narrowMatch MetaCyc:PWY-7357
+property_value: skos:narrowMatch MetaCyc:PWY-8457
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
created_by: bf
creation_date: 2012-03-29T10:31:05Z
@@ -228809,6 +236780,7 @@
xref: Reactome:R-HSA-2161844 "15k-LXA4 is reduced to dhk-LXA4 by PTGR1"
xref: RHEA:41592
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:41592
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21879" xsd:anyURI
created_by: bf
creation_date: 2012-04-16T02:28:19Z
@@ -228846,6 +236818,9 @@
xref: MetaCyc:RXN-10624
xref: RHEA:26225
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.74
+property_value: skos:exactMatch RHEA:26225
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30270" xsd:anyURI
created_by: bf
creation_date: 2012-04-18T01:46:19Z
@@ -228861,6 +236836,9 @@
xref: MetaCyc:RXN-8507
xref: RHEA:26217
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.144
+property_value: skos:exactMatch RHEA:26217
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-04-19T10:57:05Z
@@ -228873,7 +236851,10 @@
xref: KEGG_REACTION:R07403
xref: RHEA:31899
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.153
+property_value: skos:exactMatch RHEA:31899
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-04-19T11:24:48Z
@@ -228887,7 +236868,10 @@
xref: KEGG_REACTION:R07421
xref: RHEA:31919
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.157
+property_value: skos:exactMatch RHEA:31919
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19648" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-04-19T11:38:01Z
@@ -228901,7 +236885,10 @@
xref: KEGG_REACTION:R07422
xref: RHEA:31927
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.109
+property_value: skos:exactMatch RHEA:31927
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-04-19T11:45:33Z
@@ -228914,7 +236901,10 @@
xref: KEGG_REACTION:R07423
xref: RHEA:31939
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.110
+property_value: skos:exactMatch RHEA:31939
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-04-19T11:54:34Z
@@ -228989,6 +236979,9 @@
xref: KEGG_REACTION:R09859
xref: RHEA:51564
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.15.29
+property_value: skos:exactMatch RHEA:51564
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-04-20T02:03:05Z
@@ -229003,7 +236996,10 @@
xref: KEGG_REACTION:R09860
xref: RHEA:32199
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.15.30
+property_value: skos:exactMatch RHEA:32199
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27695" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-04-20T02:09:47Z
@@ -229016,6 +237012,9 @@
xref: KEGG_REACTION:R09861
xref: RHEA:56336
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.76
+property_value: skos:exactMatch RHEA:56336
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-04-20T02:21:33Z
@@ -229029,6 +237028,9 @@
xref: KEGG_REACTION:R09866
xref: RHEA:31967
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.112
+property_value: skos:exactMatch RHEA:31967
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-04-20T02:34:13Z
@@ -229041,6 +237043,9 @@
xref: KEGG_REACTION:R09867
xref: RHEA:31971
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.146
+property_value: skos:exactMatch RHEA:31971
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-04-20T02:40:54Z
@@ -229054,6 +237059,9 @@
xref: MetaCyc:RXN-12799
xref: RHEA:26221
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.145
+property_value: skos:exactMatch RHEA:26221
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-04-24T02:37:15Z
@@ -229123,7 +237131,10 @@
xref: MetaCyc:RXN-15437
xref: RHEA:31951
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.111
+property_value: skos:exactMatch RHEA:31951
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-04-25T11:11:55Z
@@ -229235,6 +237246,8 @@
xref: KEGG_REACTION:R01855
xref: RHEA:28362
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:exactMatch RHEA:28362
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-05-08T01:47:59Z
@@ -229247,6 +237260,8 @@
xref: MetaCyc:RXN0-5107
xref: RHEA:28534
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:exactMatch RHEA:28534
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-05-08T01:47:59Z
@@ -229261,6 +237276,8 @@
xref: KEGG_REACTION:R00426
xref: RHEA:29391
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:exactMatch RHEA:29391
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-05-08T01:47:59Z
@@ -229277,6 +237294,9 @@
xref: Reactome:R-HSA-2509827 "ITPA hydrolyses ITP to IMP"
xref: RHEA:29399
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:exactMatch EC:3.6.1.66
+property_value: skos:exactMatch RHEA:29399
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-05-08T01:47:59Z
@@ -229289,6 +237309,8 @@
xref: KEGG_REACTION:R00662
xref: RHEA:29395
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:exactMatch RHEA:29395
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-05-08T01:47:59Z
@@ -229308,6 +237330,10 @@
xref: Reactome:R-HSA-2509831 "ITPA hydrolyses XTP to XMP"
xref: RHEA:28610
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:broadMatch EC:3.6.1.66
+property_value: skos:exactMatch KEGG_REACTION:R02720
+property_value: skos:exactMatch MetaCyc:RXN0-1603
+property_value: skos:exactMatch RHEA:28610
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19078" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
created_by: bf
@@ -229440,6 +237466,9 @@
xref: MetaCyc:GALLATE-DIOXYGENASE-RXN
xref: RHEA:28927
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.57
+property_value: skos:exactMatch RHEA:28927
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-05-22T01:54:09Z
@@ -229450,7 +237479,16 @@
def: "Catalysis of the reaction: taxusin + [reduced NADPH-hemoprotein reductase] + O2 = 7beta-hydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O. Also converts 2alpha-hydroxytaxusin to 2alpha,7beta-dihydroxytaxusin." [EC:1.14.14.182, PMID:15157877, PMID:15178487]
xref: EC:1.14.14.182
xref: KEGG_REACTION:R09868
+xref: MetaCyc:RXN-12885
+xref: MetaCyc:RXN-13488
+xref: RHEA:31975
+xref: RHEA:71403
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.182
+property_value: skos:narrowMatch MetaCyc:RXN-12885
+property_value: skos:narrowMatch MetaCyc:RXN-13488
+property_value: skos:narrowMatch RHEA:31975
+property_value: skos:narrowMatch RHEA:71403
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24049" xsd:anyURI
created_by: bf
creation_date: 2012-05-22T02:13:21Z
@@ -229503,7 +237541,10 @@
xref: MetaCyc:SUCCSEMIALDDEHYDROG-RXN
xref: RHEA:13213
is_a: GO:0009013 ! succinate-semialdehyde dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.2.1.79
+property_value: skos:exactMatch RHEA:13213
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25781" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-05-23T02:47:52Z
@@ -230186,7 +238227,10 @@
xref: EC:2.1.1.266
xref: RHEA:43736
is_a: GO:0008988 ! rRNA (adenine-N6-)-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.266
+property_value: skos:exactMatch RHEA:43736
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24772" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-08-08T14:15:48Z
@@ -230194,9 +238238,16 @@
id: GO:0036308
name: 16S rRNA (guanine(1516)-N(2))-methyltransferase activity
namespace: molecular_function
-def: "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1516) in 16S rRNA = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine." [GOC:imk, PMID:22079366]
+def: "Catalysis of the reaction: guanosine(1516) in 16S rRNA + S-adenosyl-L-methionine = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine + H+." [PMID:22079366, RHEA:43220]
+xref: EC:2.1.1.242
+xref: MetaCyc:RXN0-6731
+xref: RHEA:43220
is_a: GO:0008990 ! rRNA (guanine-N2-)-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.242
+property_value: skos:exactMatch MetaCyc:RXN0-6731
+property_value: skos:exactMatch RHEA:43220
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: bf
creation_date: 2012-08-08T14:17:44Z
@@ -230244,6 +238295,9 @@
xref: MetaCyc:RXN-11313
xref: RHEA:27469
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.105
+property_value: skos:exactMatch MetaCyc:RXN-11313
+property_value: skos:exactMatch RHEA:27469
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
created_by: bf
creation_date: 2012-08-15T15:18:09Z
@@ -230429,6 +238483,7 @@
synonym: "PlGF-activated receptor activity" EXACT [GOC:uh, PMID:12871269]
is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity
relationship: part_of GO:0036323 ! vascular endothelial growth factor receptor-1 signaling pathway
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23056" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: bf
@@ -230588,6 +238643,9 @@
xref: MetaCyc:RXN-9781
xref: RHEA:46624
is_a: GO:0016854 ! racemase and epimerase activity
+property_value: skos:exactMatch EC:5.1.99.5
+property_value: skos:exactMatch RHEA:46624
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-09-19T10:47:56Z
@@ -230662,6 +238720,8 @@
xref: RHEA:19733
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
relationship: part_of GO:0030494 ! bacteriochlorophyll biosynthetic process
+property_value: skos:exactMatch EC:1.1.1.396
+property_value: skos:exactMatch RHEA:19733
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
created_by: bf
creation_date: 2012-09-19T14:46:31Z
@@ -230676,6 +238736,9 @@
xref: RHEA:26361
is_a: GO:0016830 ! carbon-carbon lyase activity
relationship: part_of GO:0009228 ! thiamine biosynthetic process
+property_value: skos:exactMatch EC:4.1.99.19
+property_value: skos:exactMatch RHEA:26361
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2012-09-19T14:52:51Z
@@ -230909,6 +238972,9 @@
xref: MetaCyc:RXN0-5298
xref: RHEA:25580
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.29
+property_value: skos:exactMatch RHEA:25580
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-05-07T09:51:06Z
@@ -230937,6 +239003,9 @@
xref: RHEA:28807
is_a: GO:0008242 ! omega peptidase activity
is_a: GO:0070003 ! threonine-type peptidase activity
+property_value: skos:exactMatch EC:3.4.19.13
+property_value: skos:exactMatch RHEA:28807
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-05-07T09:58:07Z
@@ -231021,6 +239090,9 @@
xref: MetaCyc:GLCNACPTRANS-RXN
xref: RHEA:28090
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.33
+property_value: skos:exactMatch RHEA:28090
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-05-23T10:51:26Z
@@ -231036,6 +239108,9 @@
xref: MetaCyc:RXN-11322
xref: RHEA:31507
is_a: GO:0016843 ! amine-lyase activity
+property_value: skos:exactMatch EC:4.3.3.6
+property_value: skos:exactMatch RHEA:31507
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-05-23T11:15:37Z
@@ -231049,6 +239124,9 @@
xref: MetaCyc:RXN-12446
xref: RHEA:31303
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.36
+property_value: skos:exactMatch RHEA:31303
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-05-23T11:23:09Z
@@ -231062,6 +239140,9 @@
xref: MetaCyc:RXN-12717
xref: RHEA:31731
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.12
+property_value: skos:exactMatch RHEA:31731
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-05-23T11:31:09Z
@@ -231076,6 +239157,8 @@
synonym: "cytidine-diphosphatase activity" EXACT []
xref: RHEA:64880
is_a: GO:0017110 ! nucleoside diphosphate phosphatase activity
+property_value: skos:exactMatch RHEA:64880
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-05-23T13:33:01Z
@@ -231240,7 +239323,10 @@
xref: MetaCyc:FORMATEDEHYDROG-RXN
xref: RHEA:48592
is_a: GO:0033695 ! oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.17.5.3
+property_value: skos:exactMatch RHEA:48592
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-07-18T13:11:41Z
@@ -231302,9 +239388,11 @@
is_a: GO:0120544 ! polypeptide conformation or assembly isomerase activity
is_a: GO:0140657 ! ATP-dependent activity
relationship: part_of GO:0010498 ! proteasomal protein catabolic process
+property_value: skos:exactMatch EC:5.6.1.5
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20879" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29690" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-08-12T11:38:20Z
@@ -231319,6 +239407,8 @@
xref: KEGG_REACTION:R07053
xref: RHEA:38675
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch RHEA:38675
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-08-14T11:48:46Z
@@ -231385,6 +239475,7 @@
synonym: "histone H3-K14 acetyltransferase activity" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H3-K14 specific)" EXACT [GOC:bf]
is_a: GO:0010484 ! histone H3 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -231430,11 +239521,13 @@
[Term]
id: GO:0036412
-name: acetyl-CoA:oxalate CoA-transferase
+name: acetyl-CoA:oxalate CoA-transferase activity
namespace: molecular_function
-def: "Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA." [GOC:imk, PMID:23935849]
+def: "Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA." [PMID:23935849, RHEA:37883]
xref: RHEA:37883
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch RHEA:37883
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-08-22T13:43:25Z
@@ -231570,8 +239663,11 @@
xref: MetaCyc:TRANS-PENTAPRENYLTRANSFERASE-RXN
xref: RHEA:27559
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.83
+property_value: skos:exactMatch RHEA:27559
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-09-16T12:22:10Z
@@ -231589,6 +239685,10 @@
xref: Reactome:R-HSA-977324 "PSPH:Mg2+ dimer dephosphorylates O-P-Ser"
xref: RHEA:21208
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.3
+property_value: skos:broadMatch MetaCyc:PSERPHOSPHA-RXN
+property_value: skos:exactMatch MetaCyc:RXN0-5114
+property_value: skos:exactMatch RHEA:21208
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20587" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21638" xsd:anyURI
created_by: bf
@@ -231624,6 +239724,8 @@
def: "Catalysis of the reaction: all-trans-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate + GDP." [RHEA:28118]
xref: RHEA:28118
is_a: GO:0047267 ! undecaprenyl-phosphate mannosyltransferase activity
+property_value: skos:exactMatch RHEA:28118
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-09-16T13:23:06Z
@@ -231660,6 +239762,9 @@
xref: MetaCyc:RXN-11832
xref: RHEA:11600
is_a: GO:0050145 ! nucleoside monophosphate kinase activity
+property_value: skos:broadMatch EC:2.7.4.14
+property_value: skos:broadMatch EC:2.7.4.25
+property_value: skos:exactMatch RHEA:11600
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29533" xsd:anyURI
created_by: bf
creation_date: 2013-09-16T14:11:48Z
@@ -231674,6 +239779,9 @@
xref: MetaCyc:RXN-7913
xref: RHEA:25094
is_a: GO:0047507 ! deoxynucleoside phosphate kinase activity, ATP as phosphate donor
+property_value: skos:broadMatch EC:2.7.4.14
+property_value: skos:broadMatch EC:2.7.4.25
+property_value: skos:exactMatch RHEA:25094
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29533" xsd:anyURI
created_by: bf
creation_date: 2013-09-16T14:11:56Z
@@ -231685,6 +239793,8 @@
def: "Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+." [RHEA:23752]
xref: RHEA:23752
is_a: GO:0009038 ! undecaprenol kinase activity
+property_value: skos:exactMatch RHEA:23752
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-09-16T14:21:04Z
@@ -231699,6 +239809,10 @@
xref: MetaCyc:UNDECAPRENOL-KINASE-RXN
xref: RHEA:28122
is_a: GO:0009038 ! undecaprenol kinase activity
+property_value: skos:exactMatch EC:2.7.1.66
+property_value: skos:exactMatch KEGG_REACTION:R05626
+property_value: skos:exactMatch MetaCyc:UNDECAPRENOL-KINASE-RXN
+property_value: skos:exactMatch RHEA:28122
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
created_by: bf
creation_date: 2013-09-16T14:21:12Z
@@ -231711,6 +239825,8 @@
xref: KEGG_REACTION:R00025
xref: RHEA:26458
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
+property_value: skos:exactMatch RHEA:26458
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-09-16T16:20:13Z
@@ -231779,13 +239895,20 @@
synonym: "oxalacetic transacetase activity" RELATED [EC:2.3.3.1]
synonym: "oxaloacetate transacetase activity" RELATED [EC:2.3.3.1]
synonym: "Re-citrate-synthase activity" RELATED [EC:2.3.3.3]
+xref: EC:2.3.3.1
xref: EC:2.3.3.16
+xref: EC:2.3.3.3
xref: KEGG_REACTION:R00351
xref: MetaCyc:CITSYN-RXN
xref: RHEA:16845
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.16
+property_value: skos:exactMatch RHEA:16845
+property_value: skos:narrowMatch EC:2.3.3.1
+property_value: skos:narrowMatch EC:2.3.3.3
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29891" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-09-30T16:21:50Z
@@ -231797,6 +239920,8 @@
xref: KEGG_REACTION:R03155
xref: RHEA:18981
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:18981
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2013-09-30T16:26:27Z
@@ -231934,7 +240059,6 @@
def: "Catalysis of the transfer of a iron-sulfur cluster from one compound (donor) to another (acceptor)." [GOC:bhm]
synonym: "Fe-S transferase activity" EXACT [GOC:bf]
xref: Reactome:R-HSA-2564828 "CIA Targeting Complex transfers 4Fe-4S cluster to apoproteins"
-xref: Reactome:R-HSA-8878815 "Formation of 4Fe-4S cluster on ISCA1:ISCA2"
is_a: GO:0016782 ! transferase activity, transferring sulphur-containing groups
created_by: bf
creation_date: 2013-11-14T11:17:37Z
@@ -232062,6 +240186,8 @@
synonym: "5-hydroxytryptophan decarboxylase activity" BROAD [EC:4.1.1.28]
xref: RHEA:18533
is_a: GO:0004058 ! aromatic-L-amino-acid decarboxylase activity
+property_value: skos:exactMatch RHEA:18533
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2014-07-21T09:22:24Z
@@ -232075,6 +240201,8 @@
synonym: "DOPA decarboxylase activity" RELATED [EC:4.1.1.28]
xref: RHEA:12272
is_a: GO:0004058 ! aromatic-L-amino-acid decarboxylase activity
+property_value: skos:exactMatch RHEA:12272
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2014-07-21T09:22:24Z
@@ -232086,6 +240214,9 @@
xref: EC:4.1.1.105
xref: RHEA:30339
is_a: GO:0004058 ! aromatic-L-amino-acid decarboxylase activity
+property_value: skos:exactMatch EC:4.1.1.105
+property_value: skos:exactMatch RHEA:30339
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2014-07-21T09:22:24Z
@@ -232548,7 +240679,7 @@
synonym: "protein degradation by ERAD" EXACT [GOC:bf]
is_a: GO:0010498 ! proteasomal protein catabolic process
is_a: GO:0034976 ! response to endoplasmic reticulum stress
-is_a: GO:1901698 ! response to nitrogen compound
+is_a: GO:0042221 ! response to chemical
created_by: bf
creation_date: 2015-05-14T11:43:06Z
@@ -232826,9 +240957,29 @@
synonym: "glyoxylase III" EXACT []
synonym: "protein deglycating enzyme" RELATED [PMID:26873906]
xref: EC:3.5.1.124
+xref: MetaCyc:RXN-17630
+xref: MetaCyc:RXN-17632
+xref: MetaCyc:RXN-17634
+xref: RHEA:49548
+xref: RHEA:49552
+xref: RHEA:49556
+xref: RHEA:57188
+xref: RHEA:57192
+xref: RHEA:57196
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:3.5.1.124
+property_value: skos:narrowMatch MetaCyc:RXN-17630
+property_value: skos:narrowMatch MetaCyc:RXN-17632
+property_value: skos:narrowMatch MetaCyc:RXN-17634
+property_value: skos:narrowMatch RHEA:49548
+property_value: skos:narrowMatch RHEA:49552
+property_value: skos:narrowMatch RHEA:49556
+property_value: skos:narrowMatch RHEA:57188
+property_value: skos:narrowMatch RHEA:57192
+property_value: skos:narrowMatch RHEA:57196
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25834" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: bf
creation_date: 2016-08-04T10:23:33Z
@@ -233233,13 +241384,11 @@
synonym: "receptor activity involved in receptor-mediated endocytosis" NARROW [GOC:bf]
synonym: "transport receptor activity" BROAD [GOC:signaling]
xref: Reactome:R-HSA-203716 "eNOS:Caveolin-1 complex binds to Nostrin"
-xref: Reactome:R-HSA-2160915 "Receptor-mediated uptake of HA"
xref: Reactome:R-HSA-3000103 "CUBN:AMN binds CBLIF:RCbl"
xref: Reactome:R-HSA-3000112 "CD320-mediated TCN2:RCbl uptake and delivery to lysosome"
xref: Reactome:R-HSA-3000122 "CD320 binds extracellular TCN2:RCbl"
xref: Reactome:R-HSA-3000137 "CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome"
xref: Reactome:R-HSA-350168 "LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D"
-xref: Reactome:R-HSA-350186 "CUBN binds GC:25(OH)D"
xref: Reactome:R-HSA-9759202 "LRP2-mediated TCN2:RCbl uptake and delivery to lysosome"
xref: Reactome:R-HSA-9759209 "LRP2 binds extracellular TCN2:RCbl"
is_a: GO:0003674 ! molecular_function
@@ -233296,7 +241445,6 @@
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25671" xsd:anyURI
is_obsolete: true
replaced_by: GO:0008286
-consider: GO:0051897
created_by: bf
creation_date: 2011-09-08T10:35:14Z
@@ -233685,6 +241833,7 @@
is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity
is_a: GO:0038064 ! collagen receptor activity
relationship: part_of GO:0038063 ! collagen-activated tyrosine kinase receptor signaling pathway
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: bf
creation_date: 2012-01-18T01:38:40Z
@@ -235573,15 +243722,16 @@
[Term]
id: GO:0039016
-name: cell-cell signaling involved in pronephros development
+name: obsolete cell-cell signaling involved in pronephros development
namespace: biological_process
-def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10]
+def: "OBSOLETE. Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "cell-cell signaling involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10]
synonym: "cell-cell signalling involved in pronephros development" EXACT [GOC:mah]
-is_a: GO:0060995 ! cell-cell signaling involved in kidney development
-intersection_of: GO:0007267 ! cell-cell signaling
-intersection_of: part_of GO:0048793 ! pronephros development
-relationship: part_of GO:0048793 ! pronephros development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007267
+consider: GO:0048793
created_by: bf
creation_date: 2010-07-02T10:03:16Z
@@ -239286,8 +247436,10 @@
xref: Reactome:R-HSA-5205861 "COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3)"
xref: Reactome:R-HSA-5216234 "PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3)"
xref: Reactome:R-HSA-9822583 "METTL23 dimethylates histone H3.3 arginine-17 (arginine-18 in the preprotein)"
+xref: RHEA:10024
is_a: GO:0008276 ! protein methyltransferase activity
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:narrowMatch RHEA:10024
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24397" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29483" xsd:anyURI
@@ -239435,10 +247587,11 @@
[Term]
id: GO:0042070
-name: maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification
+name: obsolete maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification
namespace: biological_process
alt_id: GO:0048127
-def: "Maintenance of the oocyte nucleus in a particular position within the cell during the establishment and maintenance of the axes of the oocyte. An example of this process is found In Drosophila melanogaster." [GOC:dph, GOC:mah, GOC:mtg_sensu, GOC:tb]
+def: "OBSOLETE. Maintenance of the oocyte nucleus in a particular position within the cell during the establishment and maintenance of the axes of the oocyte. An example of this process is found In Drosophila melanogaster." [GOC:dph, GOC:mah, GOC:mtg_sensu, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "maintenance of oocyte nucleus localization during oocyte axis determination" BROAD [GOC:dph, GOC:tb]
synonym: "maintenance of oocyte nucleus location involved in oocyte dorsal-ventral axis specification" EXACT [GOC:mah]
synonym: "maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis determination" EXACT [GOC:dph, GOC:tb]
@@ -239448,10 +247601,10 @@
synonym: "oocyte axis determination, maintenance of oocyte nucleus position" BROAD []
synonym: "oocyte axis determination, oocyte nucleus anchoring" BROAD []
synonym: "oocyte nucleus anchoring during oocyte axis determination" BROAD []
-is_a: GO:0051658 ! maintenance of nucleus location
-is_a: GO:0051663 ! oocyte nucleus localization involved in oocyte dorsal/ventral axis specification
-intersection_of: GO:0051658 ! maintenance of nucleus location
-intersection_of: part_of GO:0007310 ! oocyte dorsal/ventral axis specification
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007310
+consider: GO:0051658
[Term]
id: GO:0042071
@@ -239598,17 +247751,21 @@
[Term]
id: GO:0042084
-name: 5-methyltetrahydrofolate-dependent methyltransferase activity
+name: obsolete 5-methyltetrahydrofolate-dependent methyltransferase activity
namespace: molecular_function
-def: "Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate." [GOC:ai]
-is_a: GO:0008168 ! methyltransferase activity
+def: "OBSOLETE. Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate." [GOC:ai]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30968" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0042085
-name: 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity
+name: obsolete 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity
namespace: molecular_function
-def: "Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate." [GOC:ai]
-is_a: GO:0008168 ! methyltransferase activity
+def: "OBSOLETE. Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate." [GOC:ai]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30968" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0042086
@@ -239975,8 +248132,11 @@
xref: EC:3.1.3.100
xref: RHEA:47948
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.100
+property_value: skos:exactMatch RHEA:47948
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27990" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042132
@@ -240004,6 +248164,9 @@
xref: Reactome:R-HSA-70479 "FBP tetramers hydrolyze F1,6PP to Fru(6)P"
xref: RHEA:11064
is_a: GO:0050308 ! sugar-phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.11
+property_value: skos:exactMatch RHEA:11064
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042133
@@ -241023,6 +249186,9 @@
xref: EC:6.3.5.11
xref: RHEA:26289
is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor
+property_value: skos:exactMatch EC:6.3.5.11
+property_value: skos:exactMatch RHEA:26289
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042243
@@ -241364,6 +249530,8 @@
xref: Wikipedia:Cytochrome_c_nitrite_reductase
is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor
is_a: GO:0098809 ! nitrite reductase activity
+property_value: skos:exactMatch EC:1.7.2.2
+property_value: skos:exactMatch RHEA:13089
[Term]
id: GO:0042280
@@ -241387,7 +249555,10 @@
xref: RHEA:30635
is_a: GO:0004583 ! dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
relationship: part_of GO:0006488 ! dolichol-linked oligosaccharide biosynthetic process
+property_value: skos:exactMatch EC:2.4.1.267
+property_value: skos:exactMatch RHEA:30635
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28029" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042283
@@ -241399,7 +249570,10 @@
xref: MetaCyc:RXN-5471
xref: RHEA:31307
is_a: GO:0004583 ! dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.265
+property_value: skos:exactMatch RHEA:31307
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28029" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042284
@@ -241411,7 +249585,10 @@
xref: Reactome:R-HSA-428259 "DEGS1 dehydrogenates dihydroceramide"
xref: RHEA:46544
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.17
+property_value: skos:exactMatch RHEA:46544
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21105" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
@@ -241433,6 +249610,9 @@
xref: MetaCyc:GSAAMINOTRANS-RXN
xref: RHEA:14265
is_a: GO:0016869 ! intramolecular aminotransferase activity
+property_value: skos:exactMatch EC:5.4.3.8
+property_value: skos:exactMatch RHEA:14265
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042287
@@ -241515,7 +249695,6 @@
def: "Catalysis of the transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y = Y-ISG15 + X, where both X-ISG15 and Y-ISG15 are covalent linkages." [GOC:mah, PMID:12826404]
synonym: "ISG15 conjugating enzyme activity" NARROW []
xref: Reactome:R-HSA-5653754 "UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA"
-xref: Reactome:R-HSA-9927247 "ISGylation of DDX58 (RIG-I)"
is_a: GO:0019787 ! ubiquitin-like protein transferase activity
[Term]
@@ -241539,6 +249718,9 @@
xref: MetaCyc:RXN-111
xref: RHEA:31383
is_a: GO:0031559 ! oxidosqualene cyclase activity
+property_value: skos:exactMatch EC:5.4.99.41
+property_value: skos:exactMatch RHEA:31383
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042300
@@ -241551,7 +249733,10 @@
xref: MetaCyc:RXN-7570
xref: RHEA:31007
is_a: GO:0031559 ! oxidosqualene cyclase activity
+property_value: skos:exactMatch EC:5.4.99.39
+property_value: skos:exactMatch RHEA:31007
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28065" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042301
@@ -242167,7 +250352,10 @@
synonym: "guanosine diphosphate-4-keto-D-rhamnose reductase activity" RELATED [EC:1.1.1.187]
xref: EC:1.1.1.187
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch MetaCyc:GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN
+property_value: skos:exactMatch EC:1.1.1.187
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042357
@@ -242322,7 +250510,6 @@
synonym: "vitamin H catabolism" EXACT []
is_a: GO:0006768 ! biotin metabolic process
is_a: GO:0042365 ! water-soluble vitamin catabolic process
-is_a: GO:0043605 ! amide catabolic process
is_a: GO:0044273 ! sulfur compound catabolic process
is_a: GO:0072329 ! monocarboxylic acid catabolic process
@@ -242584,6 +250771,8 @@
xref: Reactome:R-HSA-428696 "PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate"
xref: RHEA:27518
is_a: GO:0042577 ! lipid phosphatase activity
+property_value: skos:exactMatch RHEA:27518
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042393
@@ -242785,6 +250974,9 @@
xref: RHEA:16925
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.104
+property_value: skos:exactMatch RHEA:16925
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042410
@@ -242801,6 +250993,9 @@
xref: RHEA:14781
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.14
+property_value: skos:exactMatch RHEA:14781
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042412
@@ -242989,9 +251184,17 @@
synonym: "choline breakdown" EXACT []
synonym: "choline catabolism" EXACT []
synonym: "choline degradation" EXACT []
+xref: MetaCyc:CHOLINE-BETAINE-ANA-PWY
+xref: MetaCyc:P542-PWY
+xref: MetaCyc:PWY-3721
+xref: MetaCyc:PWY-7494
xref: Reactome:R-HSA-6798163 "Choline catabolism"
is_a: GO:0019695 ! choline metabolic process
is_a: GO:0042402 ! biogenic amine catabolic process
+property_value: skos:narrowMatch MetaCyc:CHOLINE-BETAINE-ANA-PWY
+property_value: skos:narrowMatch MetaCyc:P542-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-3721
+property_value: skos:narrowMatch MetaCyc:PWY-7494
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30537" xsd:anyURI
@@ -244159,9 +252362,15 @@
id: GO:0042561
name: alpha-amyrin synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: (S)-2,3-epoxysqualene = alpha-amyrin. This reaction is a cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into alpha-amyrin." [GOC:jl, MetaCyc:RXN-8434, PMID:10848960]
+def: "Catalysis of the reaction: (S)-2,3-epoxysqualene = alpha-amyrin." [PMID:10848960, RHEA:31387]
+xref: EC:5.4.99.40
xref: MetaCyc:RXN-8434
+xref: RHEA:31387
is_a: GO:0031559 ! oxidosqualene cyclase activity
+property_value: skos:exactMatch EC:5.4.99.40
+property_value: skos:exactMatch MetaCyc:RXN-8434
+property_value: skos:exactMatch RHEA:31387
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0042562
@@ -244376,6 +252585,9 @@
xref: MetaCyc:3.5.1.88-RXN
xref: RHEA:24420
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.88
+property_value: skos:exactMatch RHEA:24420
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042587
@@ -244425,7 +252637,7 @@
alt_id: GO:0032844
alt_id: GO:0032845
alt_id: GO:0032846
-def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172]
+def: "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions." [PMID:26265027]
subset: goslim_agr
subset: goslim_chembl
subset: goslim_mouse
@@ -244436,6 +252648,7 @@
synonym: "positive regulation of homeostatic process" RELATED []
synonym: "regulation of homeostatic process" RELATED []
is_a: GO:0008150 ! biological_process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31175" xsd:anyURI
[Term]
id: GO:0042593
@@ -244544,6 +252757,8 @@
xref: MetaCyc:NADPH-DEHYDROGENASE-FLAVIN-RXN
xref: RHEA:19377
is_a: GO:0052875 ! riboflavin reductase [NAD(P)H] activity
+property_value: skos:exactMatch EC:1.5.1.30
+property_value: skos:exactMatch RHEA:19377
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
[Term]
@@ -244767,9 +252982,11 @@
is_a: GO:0140657 ! ATP-dependent activity
intersection_of: GO:0015399 ! primary active transmembrane transporter activity
intersection_of: has_part GO:0016887 ! ATP hydrolysis activity
+property_value: skos:exactMatch EC:7.2.2.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14642" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17373" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19965" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042627
@@ -245882,6 +254099,9 @@
xref: RHEA:12260
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.86
+property_value: skos:exactMatch RHEA:12260
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042739
@@ -246205,8 +254425,21 @@
def: "Catalysis of the reaction: 3-dehydro-2,22-dideoxyecdysone + 2 reduced [adrenodoxin] + O2 + 2 H+ = 3-dehydro-2-deoxyecdysone + 2 oxidized [adrenodoxin] + H2O. Other substrates include 3-dehydro-2,22,25-deoxyecdysone and 2,22-dideoxyecdysone." [EC:1.14.15.44, PMID:12177427]
synonym: "3-dehydro-2,22-dideoxyecdysone 22-hydroxylase activity" NARROW [EC:1.14.15.44]
xref: EC:1.14.15.44
+xref: MetaCyc:RXN-14678
+xref: MetaCyc:RXN-14681
+xref: MetaCyc:RXN-24931
+xref: RHEA:82055
+xref: RHEA:83295
+xref: RHEA:83299
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.15.44
+property_value: skos:narrowMatch MetaCyc:RXN-14678
+property_value: skos:narrowMatch MetaCyc:RXN-14681
+property_value: skos:narrowMatch MetaCyc:RXN-24931
+property_value: skos:narrowMatch RHEA:82055
+property_value: skos:narrowMatch RHEA:83295
+property_value: skos:narrowMatch RHEA:83299
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29033" xsd:anyURI
[Term]
@@ -246215,8 +254448,18 @@
namespace: molecular_function
def: "Catalysis of the hydroxylation of an ecdysteroid at carbon position 2." [PMID:12177427]
comment: Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2-deoxyecdysone to ecdysone. It can also catalyze the conversion of 2,22-dideoxyecdysone (ketotriol) to 22-deoxyecdysone.
+xref: MetaCyc:RXN-14679
+xref: MetaCyc:RXN-14682
+xref: MetaCyc:RXN-24932
+xref: RHEA:82351
+xref: RHEA:83255
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:narrowMatch MetaCyc:RXN-14679
+property_value: skos:narrowMatch MetaCyc:RXN-14682
+property_value: skos:narrowMatch MetaCyc:RXN-24932
+property_value: skos:narrowMatch RHEA:82351
+property_value: skos:narrowMatch RHEA:83255
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29033" xsd:anyURI
[Term]
@@ -246363,6 +254606,7 @@
is_a: GO:0004549 ! tRNA-specific ribonuclease activity
is_a: GO:0016891 ! RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
relationship: part_of GO:0042780 ! tRNA 3'-end processing
+property_value: skos:exactMatch EC:3.1.26.11
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21383" xsd:anyURI
[Term]
@@ -246609,7 +254853,6 @@
xref: Reactome:R-HSA-8937016 "Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter"
xref: Reactome:R-HSA-8937050 "Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter"
xref: Reactome:R-HSA-9843121 "KMT2D,(KMT2C) complex monomethylates nucleosomes at PPARG:RXRA-bound enhancers"
-xref: Reactome:R-HSA-9909628 "Trimethylation of CD274 gene chromatin by MLL1/3 complex"
is_a: GO:0016279 ! protein-lysine N-methyltransferase activity
is_a: GO:0140938 ! histone H3 methyltransferase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24866" xsd:anyURI
@@ -246994,7 +255237,15 @@
synonym: "D-glucuronate breakdown" EXACT []
synonym: "D-glucuronate catabolism" EXACT []
synonym: "D-glucuronate degradation" EXACT []
+xref: MetaCyc:PWY-5525
+xref: MetaCyc:PWY-6501
+xref: MetaCyc:PWY-7247
+xref: MetaCyc:PWY-8390
is_a: GO:0006064 ! glucuronate catabolic process
+property_value: skos:narrowMatch MetaCyc:PWY-5525
+property_value: skos:narrowMatch MetaCyc:PWY-6501
+property_value: skos:narrowMatch MetaCyc:PWY-7247
+property_value: skos:narrowMatch MetaCyc:PWY-8390
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
@@ -247129,14 +255380,17 @@
id: GO:0042852
name: L-alanine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid." [GOC:jl, GOC:jsg, GOC:mah]
+def: "The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid." [GOC:jl, GOC:jsg, GOC:mah, MetaCyc:PWY0-1061]
synonym: "L-alanine anabolism" EXACT []
synonym: "L-alanine biosynthesis" EXACT []
synonym: "L-alanine formation" EXACT []
synonym: "L-alanine synthesis" EXACT []
+xref: MetaCyc:PWY0-1061
is_a: GO:0006523 ! alanine biosynthetic process
is_a: GO:0009079 ! pyruvate family amino acid biosynthetic process
is_a: GO:0042851 ! L-alanine metabolic process
+property_value: skos:exactMatch MetaCyc:PWY0-1061
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29444" xsd:anyURI
[Term]
id: GO:0042853
@@ -247146,7 +255400,6 @@
synonym: "L-alanine breakdown" EXACT []
synonym: "L-alanine catabolism" EXACT []
synonym: "L-alanine degradation" EXACT []
-is_a: GO:0006524 ! alanine catabolic process
is_a: GO:0042851 ! L-alanine metabolic process
is_a: GO:0170035 ! L-amino acid catabolic process
is_a: GO:0170040 ! proteinogenic amino acid catabolic process
@@ -247229,7 +255482,6 @@
is_a: GO:0009713 ! catechol-containing compound biosynthetic process
is_a: GO:0019290 ! siderophore biosynthetic process
is_a: GO:0034309 ! primary alcohol biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0046394 ! carboxylic acid biosynthetic process
is_a: GO:1901162 ! primary amino compound biosynthetic process
@@ -247243,7 +255495,6 @@
synonym: "chrysobactin degradation" EXACT []
is_a: GO:0019614 ! catechol-containing compound catabolic process
is_a: GO:0034310 ! primary alcohol catabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0046215 ! siderophore catabolic process
is_a: GO:0046395 ! carboxylic acid catabolic process
is_a: GO:1901161 ! primary amino compound catabolic process
@@ -247270,7 +255521,6 @@
synonym: "achromobactin formation" EXACT []
synonym: "achromobactin synthesis" EXACT []
is_a: GO:0019290 ! siderophore biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0046394 ! carboxylic acid biosynthetic process
[Term]
@@ -247281,7 +255531,6 @@
synonym: "achromobactin breakdown" EXACT []
synonym: "achromobactin catabolism" EXACT []
synonym: "achromobactin degradation" EXACT []
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0046215 ! siderophore catabolic process
is_a: GO:0046395 ! carboxylic acid catabolic process
@@ -247468,7 +255717,7 @@
name: microcin transport
namespace: biological_process
def: "The directed movement of microcin, a class of glycine-rich, bactericidal peptides (antibiotics) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, PMID:11292337]
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0042885
@@ -247479,20 +255728,23 @@
[Term]
id: GO:0042886
-name: amide transport
+name: obsolete amide transport
namespace: biological_process
-def: "The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, ISBN:0198506732]
-subset: goslim_pir
-is_a: GO:0071705 ! nitrogen compound transport
+def: "OBSOLETE. The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, ISBN:0198506732]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31123" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0071705
[Term]
id: GO:0042887
-name: amide transmembrane transporter activity
+name: obsolete amide transmembrane transporter activity
namespace: molecular_function
-def: "Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other." [GOC:jl, ISBN:0198506732]
-synonym: "amine/amide/polyamine channel activity" NARROW []
-is_a: GO:0022857 ! transmembrane transporter activity
-relationship: part_of GO:0042886 ! amide transport
+def: "OBSOLETE. Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other." [GOC:jl, ISBN:0198506732]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31123" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0022857
[Term]
id: GO:0042888
@@ -247539,7 +255791,7 @@
def: "The directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, across a lipid bilayer, from one side of a membrane to the other." [PMID:29150447]
synonym: "chloramphenicol transport" BROAD []
is_a: GO:0015791 ! polyol transmembrane transport
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0042893
@@ -247547,14 +255799,14 @@
namespace: biological_process
def: "The directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl]
is_a: GO:0006869 ! lipid transport
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0042894
name: fosmidomycin transport
namespace: biological_process
def: "The directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, PMID:12543685]
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0042895
@@ -247573,7 +255825,6 @@
def: "Enables the transfer of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, from one side of a membrane to the other." [GOC:jl]
synonym: "chloramphenicol transporter activity" RELATED []
is_a: GO:0015166 ! polyol transmembrane transporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
relationship: part_of GO:0042892 ! chloramphenicol transmembrane transport
[Term]
@@ -247582,7 +255833,6 @@
namespace: molecular_function
def: "Enables the transfer of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, from one side of a membrane to the other." [GOC:jl, ISBN:0198506732]
synonym: "polymyxin transporter activity" RELATED []
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:0170055 ! lipid transmembrane transporter activity
relationship: part_of GO:0042893 ! polymyxin transport
@@ -247592,7 +255842,7 @@
namespace: molecular_function
def: "Enables the transfer of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, from one side of a membrane to the other." [GOC:jl, PMID:12543685]
synonym: "fosmidomycin transporter activity" RELATED []
-is_a: GO:0042887 ! amide transmembrane transporter activity
+is_a: GO:0022857 ! transmembrane transporter activity
relationship: part_of GO:0042894 ! fosmidomycin transport
[Term]
@@ -247636,6 +255886,7 @@
xref: Reactome:R-HSA-5618331 "HDAC6 deacetylates microtubules"
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0033558 ! protein lysine deacetylase activity
+property_value: skos:broadMatch EC:3.5.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -247713,15 +255964,6 @@
synonym: "xenobiotic transporter activity" RELATED []
xref: Reactome:R-HSA-5625574 "Defective SLC22A18 does not exchange extracellular organic cations for cytosolic H+"
xref: Reactome:R-HSA-597628 "SLC22A18 exchanges extracellular organic cations for cytosolic H+"
-xref: Reactome:R-HSA-9911512 "AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm"
-xref: Reactome:R-HSA-9911517 "MdfA transports tetracyclines from the cytosol to the periplasmic space"
-xref: Reactome:R-HSA-9913106 "TetB exports tetracyclines"
-xref: Reactome:R-HSA-9913128 "TetA exports tetracyclines"
-xref: Reactome:R-HSA-9913437 "Pef exports fluoroquinolones"
-xref: Reactome:R-HSA-9913672 "OqxA exports fluoroquinolones"
-xref: Reactome:R-HSA-9914089 "MdtE:MdtF:TolC exports beta-lactams to the periplasm"
-xref: Reactome:R-HSA-9931163 "Gdx dimer exports cationic aromatics to periplasm"
-xref: Reactome:R-HSA-9931565 "EmrE dimer exports xenobiotics to periplasm"
is_a: GO:0022857 ! transmembrane transporter activity
relationship: part_of GO:0042908 ! xenobiotic transport
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19460" xsd:anyURI
@@ -247856,7 +256098,7 @@
def: "A process in which ferrichrome is transported into the cell by specific cell surface receptors. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine." [GOC:jl, ISBN:0198506732, PMID:23192658]
synonym: "ferrichrome transport" BROAD []
is_a: GO:0015687 ! ferric-hydroxamate import into cell
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0042929
@@ -247865,7 +256107,6 @@
def: "Enables the directed movement of a ferrichrome from one side of a membrane to the other. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine." [GOC:jl, ISBN:0198506732]
synonym: "ferrichrome transporter activity" RELATED []
is_a: GO:0015343 ! siderophore-iron transmembrane transporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
relationship: part_of GO:0042928 ! ferrichrome import into cell
[Term]
@@ -247885,8 +256126,6 @@
def: "Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other." [GOC:jl]
synonym: "enterobactin transporter activity" RELATED []
synonym: "enterochelin transporter activity" EXACT []
-xref: Reactome:R-HSA-9911595 "EntS transports enterobactin from cytosol to periplasmic space"
-xref: Reactome:R-HSA-9911600 "Efflux pump complexes transport enterobactin from periplasmic space to extracellular region"
is_a: GO:0015343 ! siderophore-iron transmembrane transporter activity
relationship: part_of GO:0042930 ! enterobactin transport
@@ -247919,7 +256158,6 @@
def: "Enables the transfer of achromobactin, a citrate siderophore, from one side of a membrane to the other." [GOC:jl]
synonym: "achromobactin transporter activity" RELATED []
is_a: GO:0015343 ! siderophore-iron transmembrane transporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
relationship: part_of GO:0042935 ! achromobactin transport
@@ -247930,8 +256168,8 @@
def: "The directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, PMID:10928541]
is_a: GO:0015850 ! organic hydroxy compound transport
is_a: GO:0015891 ! siderophore transport
-is_a: GO:0042886 ! amide transport
is_a: GO:0046942 ! carboxylic acid transport
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0042937
@@ -248269,6 +256507,8 @@
xref: EC:3.2.1.73
xref: MetaCyc:3.2.1.73-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.73
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042973
@@ -248293,7 +256533,9 @@
xref: EC:3.2.1.39
xref: MetaCyc:3.2.1.39-RXN
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.39
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28262" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0042974
@@ -248341,7 +256583,6 @@
namespace: molecular_function
def: "Binds to and increases ornithine decarboxylase activity." [GOC:jl]
synonym: "L-ornithine carboxy-lyase activator activity" NARROW []
-xref: Reactome:R-HSA-9955574 "ODC dimerizes"
is_a: GO:0008047 ! enzyme activator activity
is_a: GO:0042979 ! ornithine decarboxylase regulator activity
relationship: positively_regulates GO:0004586 ! ornithine decarboxylase activity
@@ -248659,11 +256900,12 @@
id: GO:0043001
name: Golgi to plasma membrane protein transport
namespace: biological_process
-def: "The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane." [ISBN:0716731363]
+def: "The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. Golgi to plasma membrane transport precedes exocytosis." [ISBN:0716731363]
is_a: GO:0006893 ! Golgi to plasma membrane transport
is_a: GO:0015031 ! protein transport
is_a: GO:0061951 ! establishment of protein localization to plasma membrane
is_a: GO:0072659 ! protein localization to plasma membrane
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31197" xsd:anyURI
[Term]
id: GO:0043002
@@ -249722,6 +257964,9 @@
xref: MetaCyc:DIMETHUROPORDEHYDROG-RXN
xref: RHEA:15613
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.76
+property_value: skos:exactMatch RHEA:15613
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043116
@@ -249958,9 +258203,13 @@
synonym: "glycerol-1-phosphatase activity" BROAD [EC:3.1.3.21]
synonym: "glycerol-3-phosphatase activity" BROAD []
xref: MetaCyc:RXN-14965
-xref: Reactome:R-HSA-8955794 "PGP:Mg2+ dimer hydrolyses G3P to glycerol"
+xref: Reactome:R-HSA-8955794 "PGP:Mg2+ dimer hydrolyses 3PG to glycerol"
xref: RHEA:66372
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.21
+property_value: skos:broadMatch MetaCyc:GLYCEROL-1-PHOSPHATASE-RXN
+property_value: skos:exactMatch MetaCyc:RXN-14965
+property_value: skos:exactMatch RHEA:66372
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27964" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
@@ -249992,7 +258241,9 @@
xref: Reactome:R-HSA-9613498 "Unwinding of DNA for the nascent HIV-1 transcript"
xref: Reactome:R-HSA-9684118 "ERCC3-facilitated RNA Pol II backtracking in TC-NER"
is_a: GO:0003678 ! DNA helicase activity
+property_value: skos:exactMatch EC:5.6.2.4
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23533" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043139
@@ -250007,9 +258258,10 @@
synonym: "DNA helicase IV activity" NARROW []
xref: EC:5.6.2.3
xref: Reactome:R-HSA-6782131 "ERCC2-facilitated RNA Pol II backtracking in TC-NER"
-xref: Reactome:R-HSA-9914438 "TWNK (PEO1) unwinds double-stranded mitochondrial DNA at the replication fork"
is_a: GO:0003678 ! DNA helicase activity
+property_value: skos:exactMatch EC:5.6.2.3
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23533" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043143
@@ -250636,8 +258888,10 @@
xref: EC:7.5.2.-
is_a: GO:0015144 ! carbohydrate transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.5.2.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17289" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28098" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043212
@@ -250656,7 +258910,7 @@
name: bacteriocin transport
namespace: biological_process
def: "The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain." [GOC:mlg]
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0043214
@@ -251085,52 +259339,65 @@
[Term]
id: GO:0043256
-name: laminin complex
+name: laminin trimer
namespace: cellular_component
-def: "A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes." [GOC:jl, PMID:10842354]
+def: "A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes." [PMID:15979864, PMID:21421915, PMID:23263632]
subset: goslim_pir
+synonym: "laminin complex" BROAD []
is_a: GO:0032991 ! protein-containing complex
-relationship: part_of GO:0005604 ! basement membrane
+relationship: part_of GO:0140144 ! non-collagenous component of basement membrane
+relationship: part_of GO:0140349 ! laminin network
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
[Term]
id: GO:0043257
-name: laminin-8 complex
+name: laminin-411 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354]
+def: "A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
synonym: "laminin-411 complex" EXACT [GOC:dph, PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+synonym: "laminin-8 complex" EXACT []
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
[Term]
id: GO:0043258
-name: laminin-9 complex
+name: laminin-421 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha4, beta2 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354]
+def: "A laminin complex composed of alpha4, beta2 and gamma1 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
synonym: "laminin-421 complex" EXACT [GOC:dph, PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+synonym: "laminin-9 complex" EXACT []
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
[Term]
id: GO:0043259
-name: laminin-10 complex
+name: laminin-511 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354]
+def: "A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
+synonym: "laminin-10 complex" EXACT []
synonym: "laminin-511 complex" EXACT [GOC:dph, PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
[Term]
id: GO:0043260
-name: laminin-11 complex
+name: laminin-521 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354]
+def: "A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
+synonym: "laminin-11 complex" EXACT []
synonym: "laminin-521 complex" EXACT [GOC:dph, PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
[Term]
id: GO:0043261
-name: laminin-12 complex
+name: laminin-213 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains." [GOC:jl, PMID:10842354]
+def: "A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
+synonym: "laminin-12 complex" EXACT []
synonym: "laminin-213 complex" EXACT [GOC:dph, PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
[Term]
id: GO:0043262
@@ -251147,7 +259414,9 @@
xref: MetaCyc:RXN-10862
xref: RHEA:61436
is_a: GO:0017110 ! nucleoside diphosphate phosphatase activity
+property_value: skos:exactMatch RHEA:61436
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25812" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043263
@@ -251284,17 +259553,16 @@
[Term]
id: GO:0043272
-name: ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance
+name: obsolete ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), occurring as part of the process of jasmonic acid and ethylene-dependent systemic resistance." [GOC:jl]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), occurring as part of the process of jasmonic acid and ethylene-dependent systemic resistance." [GOC:jl]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM.
synonym: "ethylene anabolism during jasmonic acid and ethylene-dependent systemic resistance" RELATED []
synonym: "ethylene biosynthetic process during jasmonic acid and ethylene-dependent systemic resistance" RELATED [GOC:dph, GOC:tb]
synonym: "ethylene formation during jasmonic acid and ethylene-dependent systemic resistance" RELATED []
synonym: "ethylene synthesis during jasmonic acid and ethylene-dependent systemic resistance" RELATED []
-is_a: GO:0009693 ! ethylene biosynthetic process
-intersection_of: GO:0009693 ! ethylene biosynthetic process
-intersection_of: part_of GO:0009861 ! jasmonic acid and ethylene-dependent systemic resistance
-relationship: part_of GO:0009861 ! jasmonic acid and ethylene-dependent systemic resistance
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31228" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0043273
@@ -251308,8 +259576,10 @@
synonym: "single-stranded DNA-dependent CTPase activity" NARROW []
xref: RHEA:29387
is_a: GO:0017111 ! ribonucleoside triphosphate phosphatase activity
+property_value: skos:exactMatch RHEA:29387
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19078" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2015-11-11T13:05:32Z
@@ -252100,9 +260370,9 @@
[Term]
id: GO:0043337
-name: cardiolipin synthase (CMP-forming)
+name: cardiolipin synthase (CMP-forming) activity
namespace: molecular_function
-def: "Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = CMP + diphosphatidylglycerol." [GOC:jl]
+def: "Catalysis of the reaction: a CDP-1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + CMP + H+." [RHEA:32931]
synonym: "cardiolipin synthase" BROAD []
synonym: "cardiolipin synthetase" BROAD []
synonym: "CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity" EXACT []
@@ -252111,7 +260381,10 @@
xref: Reactome:R-HSA-1483063 "PG and CDP-DAG are converted to CL by CRLS1"
xref: RHEA:32931
is_a: GO:0030572 ! phosphatidyltransferase activity
+property_value: skos:exactMatch EC:2.7.8.41
+property_value: skos:exactMatch RHEA:32931
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23339" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043338
@@ -252123,6 +260396,9 @@
xref: EC:2.7.7.67
xref: RHEA:25690
is_a: GO:0070567 ! cytidylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.67
+property_value: skos:exactMatch RHEA:25690
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043353
@@ -252171,7 +260447,9 @@
synonym: "catalysis of free radical formation" BROAD []
xref: RHEA:61976
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch RHEA:61976
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14190" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30701" xsd:anyURI
[Term]
@@ -252191,7 +260469,9 @@
xref: EC:1.97.1.4
xref: MetaCyc:TDCEACT-RXN
is_a: GO:0043364 ! glycyl-radical enzyme activating activity
+property_value: skos:exactMatch EC:1.97.1.4
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14190" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043366
@@ -252918,7 +261198,6 @@
synonym: "urea decomposition" EXACT []
synonym: "urea degradation" EXACT []
is_a: GO:0019627 ! urea metabolic process
-is_a: GO:0043605 ! amide catabolic process
is_a: GO:0044282 ! small molecule catabolic process
[Term]
@@ -253069,12 +261348,12 @@
[Term]
id: GO:0043433
-name: negative regulation of DNA-binding transcription factor activity
+name: obsolete negative regulation of DNA-binding transcription factor activity
namespace: biological_process
alt_id: GO:1904168
alt_id: GO:2000824
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:jl]
-subset: gocheck_obsoletion_candidate
+def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:jl]
+comment: The reason for obsoletion is that this term represents a molecular function.
synonym: "down regulation of transcription factor activity" EXACT []
synonym: "down-regulation of transcription factor activity" EXACT []
synonym: "downregulation of transcription factor activity" EXACT []
@@ -253084,11 +261363,8 @@
synonym: "negative regulation of sequence-specific DNA binding transcription factor activity" EXACT []
synonym: "negative regulation of thyroid hormone receptor activity" NARROW []
synonym: "negative regulation of transcription factor activity" BROAD [GOC:dph, GOC:tb]
-is_a: GO:0044092 ! negative regulation of molecular function
-is_a: GO:0051090 ! regulation of DNA-binding transcription factor activity
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0003700 ! DNA-binding transcription factor activity
-relationship: negatively_regulates GO:0003700 ! DNA-binding transcription factor activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30856" xsd:anyURI
+is_obsolete: true
creation_date: 2011-07-15T10:56:12Z
[Term]
@@ -253346,7 +261622,6 @@
synonym: "regulation of pentose phosphate pathway" EXACT []
synonym: "regulation of pentose phosphate shunt" EXACT []
synonym: "regulation of pentose-phosphate pathway" EXACT []
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy
is_a: GO:0043470 ! regulation of carbohydrate catabolic process
is_a: GO:1902031 ! regulation of NADP metabolic process
@@ -253422,13 +261697,17 @@
id: GO:0043464
name: malolactic fermentation
namespace: biological_process
-def: "The anaerobic enzymatic conversion of L-malate to L-lactate and carbon dioxide, yielding energy in the form of ATP." [PMID:10427020, PMID:8808948]
+def: "The chemical reactions and pathways involving the enzymatic conversion of L-malate to L-lactate and carbon dioxide." [PMID:10427020, PMID:8808948]
+comment: Despite the name, this is not an ATP-generating fermentation process. See MetaCyc:PWY-7685.
synonym: "L-malate fermentation" BROAD []
synonym: "malate fermentation" BROAD []
synonym: "malo-lactate fermentation" EXACT []
synonym: "malolactate fermentation" EXACT []
+xref: MetaCyc:PWY-7685
xref: Wikipedia:Malolactic_fermentation
-is_a: GO:0006113 ! fermentation
+is_a: GO:0006108 ! malate metabolic process
+relationship: has_part GO:0043883 ! malolactic enzyme activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
[Term]
id: GO:0043465
@@ -253442,13 +261721,15 @@
[Term]
id: GO:0043466
-name: pyrimidine nucleobase fermentation
+name: obsolete pyrimidine nucleobase fermentation
namespace: biological_process
-def: "The anaerobic conversion of pyrimidine nucleobases, yielding energy in the form of ATP." [GOC:jl]
+def: "OBSOLETE. The anaerobic conversion of pyrimidine nucleobases, yielding energy in the form of ATP." [GOC:jl]
+comment: The reason for obsoletion is that this term is not clearly defined.
synonym: "pyrimidine base fermentation" EXACT [GOC:go_curators]
synonym: "pyrimidine fermentation" RELATED []
-is_a: GO:0006113 ! fermentation
-is_a: GO:0006208 ! pyrimidine nucleobase catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0006208
[Term]
id: GO:0043467
@@ -253607,17 +261888,15 @@
[Term]
id: GO:0043483
-name: anthocyanin biosynthetic process involved in anthocyanin accumulation in response to UV light
+name: obsolete anthocyanin biosynthetic process involved in anthocyanin accumulation in response to UV light
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of the pigment anthocyanin, contributing to anthocyanin accumulation in a tissue in response to a UV light stimulus." [GOC:dph, GOC:jl, GOC:tb]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of the pigment anthocyanin, contributing to anthocyanin accumulation in a tissue in response to a UV light stimulus." [GOC:dph, GOC:jl, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM.
synonym: "anthocyanin biosynthesis during anthocyanin accumulation in tissues in response to UV light stimulus" RELATED []
synonym: "anthocyanin biosynthetic process during anthocyanin accumulation in response to UV light" RELATED [GOC:dph, GOC:tb]
synonym: "anthocyanin biosynthetic process during anthocyanin accumulation in tissues in response to UV light stimulus" RELATED []
-is_a: GO:0009718 ! anthocyanin-containing compound biosynthetic process
-is_a: GO:0043477 ! pigment biosynthetic process involved in pigment accumulation
-intersection_of: GO:0009718 ! anthocyanin-containing compound biosynthetic process
-intersection_of: part_of GO:0043481 ! anthocyanin accumulation in tissues in response to UV light
-relationship: part_of GO:0043481 ! anthocyanin accumulation in tissues in response to UV light
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31228" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0043484
@@ -253755,8 +262034,6 @@
synonym: "protein membrane adaptor" EXACT []
synonym: "protein membrane adaptor activity" EXACT []
synonym: "protein membrane anchor" RELATED []
-xref: Reactome:R-HSA-5333678 "CPNEs bind PL"
-xref: Reactome:R-HSA-6809764 "SBF1 binds MTMR2"
is_a: GO:0030674 ! protein-macromolecule adaptor activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19090" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24964" xsd:anyURI
@@ -254174,6 +262451,8 @@
synonym: "adenosine 5'-monophosphoramidate hydrolase activity" EXACT []
xref: RHEA:67916
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch RHEA:67916
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043531
@@ -254315,7 +262594,6 @@
name: lipoamide binding
namespace: molecular_function
def: "Binding to lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group." [GOC:go_curators]
-is_a: GO:0033218 ! amide binding
is_a: GO:1901681 ! sulfur compound binding
[Term]
@@ -254962,33 +263240,34 @@
[Term]
id: GO:0043603
-name: amide metabolic process
+name: obsolete amide metabolic process
namespace: biological_process
-def: "The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells." [GOC:curators]
-comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
-subset: gocheck_do_not_annotate
-subset: goslim_pir
-synonym: "amide metabolism" EXACT []
-synonym: "cellular amide metabolic process" EXACT []
-is_a: GO:0008152 ! metabolic process
+def: "OBSOLETE. The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells." [GOC:curators]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27189" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31123" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0008152
[Term]
id: GO:0043604
-name: amide biosynthetic process
+name: obsolete amide biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators]
-is_a: GO:0009058 ! biosynthetic process
-is_a: GO:0043603 ! amide metabolic process
+def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31123" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0009058
[Term]
id: GO:0043605
-name: amide catabolic process
+name: obsolete amide catabolic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators]
-synonym: "cellular amide catabolic process" EXACT []
-is_a: GO:0009056 ! catabolic process
-is_a: GO:0043603 ! amide metabolic process
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators]
+comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31123" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0009056
[Term]
id: GO:0043606
@@ -255349,7 +263628,6 @@
is_a: GO:0009805 ! coumarin biosynthetic process
is_a: GO:0016138 ! glycoside biosynthetic process
is_a: GO:0017000 ! antibiotic biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0046189 ! phenol-containing compound biosynthetic process
is_a: GO:1901503 ! ether biosynthetic process
@@ -255744,6 +264022,10 @@
is_a: GO:0005375 ! copper ion transmembrane transporter activity
is_a: GO:0015662 ! P-type ion transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
+property_value: skos:exactMatch EC:7.2.2.9
+property_value: skos:exactMatch RHEA:10376
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30958" xsd:anyURI
[Term]
id: GO:0043683
@@ -256020,6 +264302,9 @@
xref: MetaCyc:RXN-7743
xref: RHEA:19045
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.3.21
+property_value: skos:exactMatch RHEA:19045
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043715
@@ -256035,6 +264320,9 @@
xref: MetaCyc:R82-RXN
xref: RHEA:18769
is_a: GO:0016862 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups
+property_value: skos:exactMatch EC:5.3.2.5
+property_value: skos:exactMatch RHEA:18769
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043716
@@ -256048,6 +264336,8 @@
xref: MetaCyc:R83-RXN
xref: RHEA:14481
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.87
+property_value: skos:exactMatch RHEA:14481
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -256059,6 +264349,8 @@
xref: MetaCyc:RXN-1083
xref: RHEA:42448
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch RHEA:42448
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043718
@@ -256073,6 +264365,9 @@
xref: RHEA:15505
xref: Wikipedia:2-hydroxymethylglutarate_dehydrogenase
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.291
+property_value: skos:exactMatch RHEA:15505
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043719
@@ -256096,6 +264391,8 @@
xref: MetaCyc:R125-RXN
xref: RHEA:31555
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch RHEA:31555
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043721
@@ -256111,6 +264408,9 @@
xref: MetaCyc:RXN-8890
xref: RHEA:26530
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.120
+property_value: skos:exactMatch RHEA:26530
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043722
@@ -256127,6 +264427,9 @@
xref: MetaCyc:4.1.1.83-RXN
xref: RHEA:22732
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.83
+property_value: skos:exactMatch RHEA:22732
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043723
@@ -256161,7 +264464,10 @@
xref: MetaCyc:RIBOPHOSPHAT-RXN
xref: RHEA:25197
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.104
+property_value: skos:exactMatch RHEA:25197
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27990" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043727
@@ -256190,6 +264496,9 @@
xref: EC:3.5.1.102
xref: RHEA:27282
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.102
+property_value: skos:exactMatch RHEA:27282
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043730
@@ -256207,6 +264516,9 @@
xref: MetaCyc:RXN-7573
xref: RHEA:27333
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.114
+property_value: skos:exactMatch RHEA:27333
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043732
@@ -256222,6 +264534,9 @@
xref: MetaCyc:RXN-7585
xref: RHEA:22808
is_a: GO:0016727 ! oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor
+property_value: skos:exactMatch EC:1.17.3.3
+property_value: skos:exactMatch RHEA:22808
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043733
@@ -256272,6 +264587,8 @@
xref: EC:3.1.21.7
xref: MetaCyc:3.1.21.7-RXN
is_a: GO:0016888 ! DNA endonuclease activity, producing 5'-phosphomonoesters
+property_value: skos:exactMatch EC:3.1.21.7
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043738
@@ -256284,6 +264601,9 @@
xref: MetaCyc:RXN-8106
xref: RHEA:54752
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.98.3
+property_value: skos:exactMatch RHEA:54752
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043739
@@ -256295,6 +264615,7 @@
synonym: "uracil mismatch repair protein" BROAD []
is_a: GO:0004844 ! uracil DNA N-glycosylase activity
is_a: GO:0008263 ! pyrimidine-specific mismatch base pair DNA N-glycosylase activity
+property_value: skos:broadMatch EC:3.2.2.28
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25051" xsd:anyURI
[Term]
@@ -256310,7 +264631,10 @@
xref: MetaCyc:RXN-10055
xref: RHEA:22468
is_a: GO:0003933 ! GTP cyclohydrolase activity
+property_value: skos:exactMatch EC:3.5.4.29
+property_value: skos:exactMatch RHEA:22468
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26710" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043741
@@ -256331,6 +264655,9 @@
xref: EC:2.7.8.28
xref: RHEA:27510
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.8.28
+property_value: skos:exactMatch RHEA:27510
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043744
@@ -256346,6 +264673,8 @@
xref: RHEA:41944
is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor
is_a: GO:0019202 ! amino acid kinase activity
+property_value: skos:exactMatch RHEA:41944
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043745
@@ -256384,6 +264713,8 @@
xref: EC:4.2.1.113
xref: RHEA:10196
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.113
+property_value: skos:exactMatch RHEA:10196
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
[Term]
@@ -256413,6 +264744,9 @@
xref: MetaCyc:2.4.1.57-RXN
xref: RHEA:47368
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.345
+property_value: skos:exactMatch RHEA:47368
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043751
@@ -256437,9 +264771,15 @@
synonym: "RTP:adenosylcobinamide phosphotransferase activity" EXACT []
xref: EC:2.7.1.156
xref: MetaCyc:2.7.1.156-RXN
+xref: RHEA:15765
+xref: RHEA:15769
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.156
+property_value: skos:narrowMatch RHEA:15765
+property_value: skos:narrowMatch RHEA:15769
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28340" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043754
@@ -256455,7 +264795,13 @@
synonym: "enzyme-dihydrolipoyllysine:2-methylpropanoyl-CoA S-(2-methylpropanoyl)transferase activity" EXACT []
xref: EC:2.3.1.168
xref: MetaCyc:2.3.1.168-RXN
+xref: RHEA:18865
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:broadMatch EC:1.2.1.25
+property_value: skos:broadMatch MetaCyc:1.2.1.25-RXN
+property_value: skos:exactMatch EC:2.3.1.168
+property_value: skos:exactMatch MetaCyc:2.3.1.168-RXN
+property_value: skos:narrowMatch RHEA:18865
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17835" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29951" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30031" xsd:anyURI
@@ -256474,6 +264820,9 @@
xref: MetaCyc:RXN-16788
xref: RHEA:24456
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.73
+property_value: skos:exactMatch RHEA:24456
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043756
@@ -256489,6 +264838,9 @@
xref: MetaCyc:R346-RXN
xref: RHEA:23504
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.90
+property_value: skos:exactMatch RHEA:23504
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043757
@@ -256502,6 +264854,9 @@
xref: MetaCyc:RXN-6261
xref: RHEA:21896
is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity
+property_value: skos:exactMatch EC:6.3.1.10
+property_value: skos:exactMatch RHEA:21896
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043758
@@ -256519,6 +264874,9 @@
xref: MetaCyc:ACETATE--COA-LIGASE-ADP-FORMING-RXN
xref: RHEA:15081
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.13
+property_value: skos:exactMatch RHEA:15081
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043759
@@ -256531,8 +264889,10 @@
synonym: "branched-chain acyl-CoA synthetase (ADP-forming) activity" RELATED []
xref: RHEA:46180
is_a: GO:0031955 ! short-chain fatty acid-CoA ligase activity
+property_value: skos:exactMatch RHEA:46180
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18967" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26440" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043760
@@ -256552,6 +264912,8 @@
synonym: "CDP-2,3-di-O-geranylgeranyl-sn-glycerol:l-serine O-archaetidyltransferase activity" EXACT []
xref: EC:2.7.8.38
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.38
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043763
@@ -256589,6 +264951,9 @@
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
relationship: part_of GO:0071952 ! conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA
+property_value: skos:exactMatch EC:2.5.1.73
+property_value: skos:exactMatch RHEA:25686
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043767
@@ -256601,6 +264966,9 @@
xref: MetaCyc:6.1.1.26-RXN
xref: RHEA:19277
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.26
+property_value: skos:exactMatch RHEA:19277
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043768
@@ -256617,6 +264985,9 @@
xref: MetaCyc:RIBOSYLHOMOCYSTEINASE-RXN
xref: RHEA:17753
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.21
+property_value: skos:exactMatch RHEA:17753
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043769
@@ -256632,8 +265003,18 @@
namespace: molecular_function
def: "Catalysis of the reaction: a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H+ + S-adenosyl-L-homocysteine. Reaction substrates can have varying polyprenyl side chain length." [PMID:1444716, PMID:9045837, RHEA:42640]
xref: EC:2.1.1.163
+xref: MetaCyc:ADOMET-DMK-METHYLTRANSFER-RXN
xref: MetaCyc:RXN-11046
+xref: MetaCyc:RXN-9191
+xref: RHEA:26466
+xref: RHEA:42640
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.163
+property_value: skos:exactMatch MetaCyc:RXN-11046
+property_value: skos:narrowMatch MetaCyc:ADOMET-DMK-METHYLTRANSFER-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-9191
+property_value: skos:narrowMatch RHEA:26466
+property_value: skos:narrowMatch RHEA:42640
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -256647,8 +265028,11 @@
xref: RHEA:24674
is_a: GO:0019206 ! nucleoside kinase activity
relationship: part_of GO:0009224 ! CMP biosynthetic process
+property_value: skos:exactMatch EC:2.7.1.213
+property_value: skos:exactMatch RHEA:24674
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25077" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27917" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043772
@@ -256679,6 +265063,9 @@
xref: EC:6.3.2.32
xref: RHEA:42332
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.32
+property_value: skos:exactMatch RHEA:42332
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043776
@@ -256692,6 +265079,8 @@
xref: MetaCyc:RXN-8766
xref: RHEA:36067
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch RHEA:36067
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043777
@@ -256705,6 +265094,8 @@
xref: MetaCyc:RXN-8767
xref: RHEA:34591
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch RHEA:34591
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043778
@@ -256718,6 +265109,9 @@
xref: MetaCyc:RXN-8768
xref: RHEA:16209
is_a: GO:0016867 ! intramolecular acyltransferase activity
+property_value: skos:exactMatch EC:5.4.99.60
+property_value: skos:exactMatch RHEA:16209
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043779
@@ -256728,7 +265122,10 @@
xref: EC:3.7.1.12
xref: MetaCyc:RXN-8763
xref: RHEA:26281
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.12
+property_value: skos:exactMatch RHEA:26281
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043780
@@ -256739,6 +265136,8 @@
xref: MetaCyc:RXN-8764
xref: RHEA:26285
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch RHEA:26285
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043781
@@ -256753,6 +265152,9 @@
xref: MetaCyc:RXN-8760
xref: RHEA:17997
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.151
+property_value: skos:exactMatch RHEA:17997
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043782
@@ -256766,6 +265168,8 @@
xref: MetaCyc:RXN-8761
xref: RHEA:26273
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch RHEA:26273
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043783
@@ -256792,6 +265196,9 @@
xref: MetaCyc:2.8.3.17-RXN
xref: RHEA:15601
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.17
+property_value: skos:exactMatch RHEA:15601
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043786
@@ -256800,7 +265207,9 @@
def: "Catalysis of the reaction: 3-phenylpropanoate + NAD+ = (E)-cinnamate + NADH + H+." [PMID:10849007, RHEA:50944]
xref: RHEA:50944
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:50944
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24753" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043791
@@ -256818,6 +265227,9 @@
xref: MetaCyc:RXN-8100
xref: RHEA:41175
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.249
+property_value: skos:exactMatch RHEA:41175
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043792
@@ -256830,6 +265242,9 @@
xref: MetaCyc:3.5.2.18-RXN
xref: RHEA:17209
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.18
+property_value: skos:exactMatch RHEA:17209
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043793
@@ -256838,7 +265253,16 @@
def: "Catalysis of the reaction: 4-hydroxybenzoate + 5-phospho-alpha-D-ribose 1-diphosphate + H+ = 4-(beta-D-ribofuranosyl)phenol 5'-phosphate + CO2 + diphosphate. Both 4-hydroxybenzoate and 4-aminobenzoate may be used as substrates, but only the former is known to be produced by methanogenic archaea." [EC:2.4.2.54, PMID:12142414]
synonym: "beta-RFAP synthase activity" EXACT []
xref: EC:2.4.2.54
+xref: MetaCyc:RXN-22578
+xref: MetaCyc:RXN-8124
+xref: RHEA:35815
+xref: RHEA:48556
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.54
+property_value: skos:narrowMatch MetaCyc:RXN-22578
+property_value: skos:narrowMatch MetaCyc:RXN-8124
+property_value: skos:narrowMatch RHEA:35815
+property_value: skos:narrowMatch RHEA:48556
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -256851,6 +265275,9 @@
xref: MetaCyc:RXN-15617
xref: RHEA:42764
is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups
+property_value: skos:exactMatch EC:1.17.98.3
+property_value: skos:exactMatch MetaCyc:RXN-15617
+property_value: skos:exactMatch RHEA:42764
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28347" xsd:anyURI
[Term]
@@ -256861,6 +265288,9 @@
xref: EC:1.2.99.8
xref: RHEA:36047
is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors
+property_value: skos:exactMatch EC:1.2.99.8
+property_value: skos:exactMatch RHEA:36047
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043796
@@ -256871,7 +265301,10 @@
xref: EC:1.2.1.89
xref: RHEA:40163
is_a: GO:0033721 ! aldehyde dehydrogenase (NADP+) activity
+property_value: skos:exactMatch EC:1.2.1.89
+property_value: skos:exactMatch RHEA:40163
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043797
@@ -256886,6 +265319,9 @@
xref: MetaCyc:1.2.7.6-RXN
xref: RHEA:24148
is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.2.7.6
+property_value: skos:exactMatch RHEA:24148
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043798
@@ -256899,6 +265335,9 @@
xref: RHEA:27377
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.165
+property_value: skos:exactMatch RHEA:27377
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043799
@@ -256907,7 +265346,24 @@
def: "Catalysis of the reactions: (1) glycine + H2O + O2 = glyoxylate + NH3 + hydrogen peroxide; (2) D-alanine + H2O + O2 = pyruvate + NH3 + hydrogen peroxide; (3) sarcosine + H2O + O2 = glyoxylate + methylamine + hydrogen peroxide; (4) N-ethylglycine + H2O + O2 = glyoxylate + ethylamine + hydrogen peroxide." [EC:1.4.3.19]
synonym: "glycine:oxygen oxidoreductase (deaminating)" EXACT []
xref: EC:1.4.3.19
+xref: MetaCyc:1.4.3.19-RXN
+xref: MetaCyc:RXN-8672
+xref: MetaCyc:RXN-8673
+xref: MetaCyc:RXN-8674
+xref: RHEA:11532
+xref: RHEA:12472
+xref: RHEA:15165
+xref: RHEA:22688
is_a: GO:0052595 ! aliphatic amine oxidase activity
+property_value: skos:exactMatch EC:1.4.3.19
+property_value: skos:narrowMatch MetaCyc:1.4.3.19-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-8672
+property_value: skos:narrowMatch MetaCyc:RXN-8673
+property_value: skos:narrowMatch MetaCyc:RXN-8674
+property_value: skos:narrowMatch RHEA:11532
+property_value: skos:narrowMatch RHEA:12472
+property_value: skos:narrowMatch RHEA:15165
+property_value: skos:narrowMatch RHEA:22688
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -256921,7 +265377,10 @@
xref: MetaCyc:R12-RXN
xref: RHEA:25900
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.27
+property_value: skos:exactMatch RHEA:25900
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29695" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043801
@@ -256932,6 +265391,9 @@
xref: MetaCyc:R10-RXN
xref: RHEA:25201
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.43
+property_value: skos:exactMatch RHEA:25201
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043802
@@ -256946,6 +265408,9 @@
xref: MetaCyc:R341-RXN
xref: RHEA:12544
is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor
+property_value: skos:exactMatch EC:6.3.5.9
+property_value: skos:exactMatch RHEA:12544
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043803
@@ -256959,6 +265424,9 @@
xref: EC:2.1.1.210
xref: RHEA:30903
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.210
+property_value: skos:exactMatch RHEA:30903
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043804
@@ -256968,6 +265436,8 @@
comment: Note that this reaction can occur spontaneously (see RHEA:24937).
xref: RHEA:24935
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch RHEA:24935
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
@@ -256983,6 +265453,9 @@
xref: MetaCyc:1.2.7.8-RXN
xref: RHEA:12645
is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.2.7.8
+property_value: skos:exactMatch RHEA:12645
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043806
@@ -257016,6 +265489,9 @@
xref: MetaCyc:1.2.7.7-RXN
xref: RHEA:11712
is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.2.7.7
+property_value: skos:exactMatch RHEA:11712
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043808
@@ -257034,6 +265510,9 @@
xref: EC:2.3.2.30
xref: RHEA:20633
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.2.30
+property_value: skos:exactMatch RHEA:20633
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043811
@@ -257043,7 +265522,10 @@
xref: EC:2.3.1.274
xref: RHEA:42292
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.274
+property_value: skos:exactMatch RHEA:42292
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18530" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043812
@@ -257055,6 +265537,7 @@
xref: RHEA:55652
is_a: GO:0034596 ! phosphatidylinositol phosphate 4-phosphatase activity
is_a: GO:0052744 ! phosphatidylinositol monophosphate phosphatase activity
+property_value: skos:exactMatch RHEA:55652
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24252" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30293" xsd:anyURI
@@ -257073,6 +265556,7 @@
is_a: GO:0034595 ! phosphatidylinositol phosphate 5-phosphatase activity
is_a: GO:0106018 ! phosphatidylinositol-3,5-bisphosphate phosphatase activity
relationship: part_of GO:0036092 ! phosphatidylinositol-3-phosphate biosynthetic process
+property_value: skos:exactMatch RHEA:32955
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24773" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30293" xsd:anyURI
@@ -257084,6 +265568,9 @@
xref: EC:2.7.7.68
xref: RHEA:63424
is_a: GO:0070568 ! guanylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.68
+property_value: skos:exactMatch RHEA:63424
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043815
@@ -257098,6 +265585,9 @@
xref: MetaCyc:GARTRANSFORMYL2-RXN
xref: RHEA:24829
is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity
+property_value: skos:exactMatch EC:6.3.1.21
+property_value: skos:exactMatch MetaCyc:GARTRANSFORMYL2-RXN
+property_value: skos:exactMatch RHEA:24829
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -257112,6 +265602,9 @@
xref: EC:6.1.1.27
xref: RHEA:25678
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.27
+property_value: skos:exactMatch RHEA:25678
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043817
@@ -257127,7 +265620,10 @@
xref: MetaCyc:4.4.1.19-RXN
xref: RHEA:22784
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.19
+property_value: skos:exactMatch RHEA:22784
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043818
@@ -257142,6 +265638,9 @@
xref: MetaCyc:R321-RXN
xref: RHEA:17293
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.83
+property_value: skos:exactMatch RHEA:17293
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043819
@@ -257156,6 +265655,9 @@
xref: MetaCyc:R322-RXN
xref: RHEA:18261
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.152
+property_value: skos:exactMatch RHEA:18261
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043820
@@ -257177,6 +265679,8 @@
xref: MetaCyc:RXN0-268
xref: RHEA:28010
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch RHEA:28010
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043822
@@ -257189,6 +265693,8 @@
xref: EC:3.1.26.8
xref: MetaCyc:3.1.26.8-RXN
is_a: GO:0016891 ! RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
+property_value: skos:exactMatch EC:3.1.26.8
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043823
@@ -257199,6 +265705,9 @@
xref: MetaCyc:RXN-10670
xref: RHEA:33027
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.15.9
+property_value: skos:exactMatch RHEA:33027
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043824
@@ -257217,6 +265726,9 @@
xref: MetaCyc:SUCCGLUALDDEHYD-RXN
xref: RHEA:10812
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.71
+property_value: skos:exactMatch RHEA:10812
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043825
@@ -257237,6 +265749,9 @@
xref: MetaCyc:SUCCORNTRANSAM-RXN
xref: RHEA:16953
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.81
+property_value: skos:exactMatch RHEA:16953
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043826
@@ -257264,7 +265779,10 @@
xref: EC:2.1.1.219
xref: RHEA:41740
is_a: GO:0016426 ! tRNA (adenine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.219
+property_value: skos:exactMatch RHEA:41740
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26105" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043828
@@ -257276,6 +265794,9 @@
xref: RHEA:42716
is_a: GO:0016785 ! selenotransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.9.1.3
+property_value: skos:exactMatch RHEA:42716
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043829
@@ -257288,7 +265809,10 @@
xref: EC:3.5.4.34
xref: RHEA:50968
is_a: GO:0008251 ! tRNA-specific adenosine deaminase activity
+property_value: skos:exactMatch EC:3.5.4.34
+property_value: skos:exactMatch RHEA:50968
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24880" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043830
@@ -257317,6 +265841,9 @@
xref: MetaCyc:1.8.5.2-RXN
xref: RHEA:10936
is_a: GO:0016672 ! oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.8.5.2
+property_value: skos:exactMatch RHEA:10936
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043833
@@ -257331,7 +265858,20 @@
synonym: "monomethylamine-specific methylcobalamin:coenzyme M methyltransferase activity" NARROW []
synonym: "MT2-A" BROAD [EC:2.1.1.247]
xref: EC:2.1.1.247
+xref: MetaCyc:RXN-8099
+xref: MetaCyc:RXN-8101
+xref: MetaCyc:RXN-8103
+xref: RHEA:18773
+xref: RHEA:45216
+xref: RHEA:45220
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.247
+property_value: skos:narrowMatch MetaCyc:RXN-8099
+property_value: skos:narrowMatch MetaCyc:RXN-8101
+property_value: skos:narrowMatch MetaCyc:RXN-8103
+property_value: skos:narrowMatch RHEA:18773
+property_value: skos:narrowMatch RHEA:45216
+property_value: skos:narrowMatch RHEA:45220
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -257349,6 +265889,9 @@
xref: MetaCyc:RXN-8102
xref: RHEA:39287
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.250
+property_value: skos:exactMatch RHEA:39287
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043835
@@ -257381,7 +265924,10 @@
xref: EC:1.4.1.23
xref: RHEA:30763
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.23
+property_value: skos:exactMatch RHEA:30763
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043838
@@ -257437,7 +265983,19 @@
synonym: "3-deoxy-D-manno-octulosonic-acid transferase activity" EXACT []
synonym: "kdtA" RELATED []
synonym: "WaaA" RELATED []
+xref: EC:2.4.99.12
+xref: EC:2.4.99.13
+xref: EC:2.4.99.14
+xref: EC:2.4.99.15
+xref: MetaCyc:KDOTRANS-RXN
+xref: MetaCyc:KDOTRANS2-RXN
is_a: GO:0016757 ! glycosyltransferase activity
+property_value: skos:narrowMatch EC:2.4.99.12
+property_value: skos:narrowMatch EC:2.4.99.13
+property_value: skos:narrowMatch EC:2.4.99.14
+property_value: skos:narrowMatch EC:2.4.99.15
+property_value: skos:narrowMatch MetaCyc:KDOTRANS-RXN
+property_value: skos:narrowMatch MetaCyc:KDOTRANS2-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
[Term]
@@ -257452,6 +266010,9 @@
xref: RHEA:11460
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.147
+property_value: skos:exactMatch RHEA:11460
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043844
@@ -257466,6 +266027,9 @@
xref: RHEA:20105
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.146
+property_value: skos:exactMatch RHEA:20105
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043845
@@ -257541,6 +266105,9 @@
xref: MetaCyc:RXN-8098
xref: RHEA:26059
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.248
+property_value: skos:exactMatch RHEA:26059
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043853
@@ -257605,6 +266172,9 @@
xref: MetaCyc:2.1.3.9-RXN
xref: RHEA:18609
is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity
+property_value: skos:exactMatch EC:2.1.3.9
+property_value: skos:exactMatch RHEA:18609
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043858
@@ -257618,7 +266188,9 @@
is_a: GO:0015171 ! amino acid transmembrane transporter activity
is_a: GO:0015297 ! antiporter activity
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
+property_value: skos:exactMatch RHEA:34991
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043859
@@ -257674,6 +266246,8 @@
xref: MetaCyc:4-HYDROXY-2-KETOPIMELATE-LYSIS-RXN
xref: RHEA:25788
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch RHEA:25788
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043864
@@ -257688,7 +266262,9 @@
xref: MetaCyc:G-5841
xref: RHEA:34371
is_a: GO:0004040 ! amidase activity
+property_value: skos:exactMatch RHEA:34371
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043865
@@ -257717,6 +266293,9 @@
xref: EC:1.8.4.10
xref: RHEA:21976
is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
+property_value: skos:exactMatch EC:1.8.4.10
+property_value: skos:exactMatch RHEA:21976
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043867
@@ -257745,6 +266324,8 @@
xref: MetaCyc:RXN-5183
xref: RHEA:41948
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:41948
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043871
@@ -257783,6 +266364,8 @@
xref: MetaCyc:PYFLAVOXRE-RXN
xref: RHEA:44140
is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch RHEA:44140
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043874
@@ -257798,6 +266381,9 @@
xref: Reactome:R-HSA-1237129 "Acireductone is created"
xref: RHEA:21700
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.77
+property_value: skos:exactMatch RHEA:21700
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043875
@@ -257811,7 +266397,9 @@
xref: MetaCyc:KETOBUTFORMLY-RXN
xref: RHEA:28054
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch RHEA:28054
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28073" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043876
@@ -257825,8 +266413,14 @@
synonym: "low-specificity D-threonine aldolase" NARROW []
xref: EC:4.1.2.42
xref: MetaCyc:4.1.2.42-RXN
+xref: RHEA:15257
+xref: RHEA:20073
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.42
+property_value: skos:narrowMatch RHEA:15257
+property_value: skos:narrowMatch RHEA:20073
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043877
@@ -257850,7 +266444,9 @@
xref: MetaCyc:RXN-3443
xref: RHEA:42760
is_a: GO:0120533 ! glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (non-phosphorylating) activity
+property_value: skos:exactMatch RHEA:42760
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28144" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043879
@@ -257876,6 +266472,8 @@
xref: EC:1.3.1.86
xref: RHEA:27906
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.86
+property_value: skos:exactMatch RHEA:27906
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
[Term]
@@ -257908,7 +266506,9 @@
xref: RHEA:72295
is_a: GO:0015140 ! malate transmembrane transporter activity
is_a: GO:0017153 ! sodium:dicarboxylate symporter activity
+property_value: skos:exactMatch RHEA:72295
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043883
@@ -257921,6 +266521,9 @@
xref: MetaCyc:RXN-16819
xref: RHEA:46276
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.101
+property_value: skos:exactMatch MetaCyc:RXN-16819
+property_value: skos:exactMatch RHEA:46276
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
@@ -257937,6 +266540,9 @@
xref: MetaCyc:ACETYLSYNCLTH-RXN
xref: RHEA:45212
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.169
+property_value: skos:exactMatch RHEA:45212
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043885
@@ -257958,7 +266564,10 @@
xref: RHEA:21040
xref: UM-BBD_reactionID:r0652
is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.2.7.4
+property_value: skos:exactMatch RHEA:21040
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25872" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043886
@@ -258044,6 +266653,8 @@
xref: Reactome:R-HSA-1630304 "GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate"
xref: Reactome:R-HSA-2263490 "Defective GALNS does not hydrolyse sulfate from Gal6S in keratan sulfate"
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.4
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043891
@@ -258058,6 +266669,8 @@
xref: EC:1.2.1.59
xref: MetaCyc:GAPDHSYNEC-RXN
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.59
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043892
@@ -258072,7 +266685,10 @@
xref: MetaCyc:1.1.1.283-RXN
xref: RHEA:21748
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.283
+property_value: skos:exactMatch RHEA:21748
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043893
@@ -258126,6 +266742,8 @@
xref: EC:2.4.1.19
xref: MetaCyc:2.4.1.19-RXN
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.19
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043896
@@ -258141,7 +266759,9 @@
xref: EC:3.2.1.70
xref: MetaCyc:3.2.1.70-RXN
is_a: GO:0090599 ! alpha-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.70
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28262" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043897
@@ -258154,6 +266774,8 @@
xref: EC:3.2.1.133
xref: MetaCyc:3.2.1.133-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.133
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043898
@@ -258223,6 +266845,9 @@
xref: MetaCyc:RXN-1981
xref: RHEA:27874
is_a: GO:0016835 ! carbon-oxygen lyase activity
+property_value: skos:exactMatch EC:4.2.99.21
+property_value: skos:exactMatch RHEA:27874
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043905
@@ -258256,6 +266881,9 @@
xref: MetaCyc:RXN-21077
xref: RHEA:25351
is_a: GO:0002161 ! aminoacyl-tRNA deacylase activity
+property_value: skos:exactMatch EC:3.6.1.n2
+property_value: skos:exactMatch MetaCyc:RXN-21077
+property_value: skos:exactMatch RHEA:25351
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21843" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29746" xsd:anyURI
@@ -258278,6 +266906,8 @@
synonym: "N-acetyl-L-citrulline deacetylase activity" EXACT []
xref: RHEA:61092
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch RHEA:61092
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043910
@@ -258333,6 +266963,8 @@
synonym: "NSR" EXACT []
xref: EC:1.8.1.18
is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors
+property_value: skos:exactMatch EC:1.8.1.18
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043915
@@ -258346,6 +266978,9 @@
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.7.1.164
+property_value: skos:exactMatch RHEA:25037
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043916
@@ -258353,6 +266988,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site." [GOC:jl, PMID:16468998]
is_a: GO:0003905 ! alkylbase DNA N-glycosylase activity
+property_value: skos:broadMatch EC:3.2.2.21
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
@@ -258366,6 +267002,9 @@
xref: MetaCyc:RXN-8801
xref: RHEA:32243
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.29
+property_value: skos:exactMatch RHEA:32243
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043918
@@ -258375,6 +267014,8 @@
synonym: "cadaverine aminopropyl transferase activity" EXACT []
xref: RHEA:33387
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:broadMatch EC:2.5.1.104
+property_value: skos:exactMatch RHEA:33387
[Term]
id: GO:0043919
@@ -258384,6 +267025,8 @@
synonym: "agmatine aminopropyl transferase activity" EXACT []
xref: RHEA:36487
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:broadMatch EC:2.5.1.104
+property_value: skos:exactMatch RHEA:36487
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -258394,6 +267037,9 @@
xref: EC:3.5.3.24
xref: RHEA:35827
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.24
+property_value: skos:exactMatch RHEA:35827
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043921
@@ -258431,7 +267077,6 @@
namespace: molecular_function
def: "Binding to suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms." [GOC:jl, Wikipedia:Suramin]
synonym: "Germanin binding" EXACT []
-is_a: GO:0033218 ! amide binding
is_a: GO:0043168 ! anion binding
is_a: GO:0043177 ! organic acid binding
is_a: GO:1901681 ! sulfur compound binding
@@ -258458,25 +267103,27 @@
[Term]
id: GO:0043929
-name: primary ovarian follicle growth involved in double layer follicle stage
+name: obsolete primary ovarian follicle growth involved in double layer follicle stage
namespace: biological_process
-def: "Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle), as part of the double layer follicle stage of oogenesis." [GOC:mtg_mpo]
+def: "OBSOLETE. Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle), as part of the double layer follicle stage of oogenesis." [GOC:mtg_mpo]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "primary ovarian follicle growth during double layer follicle stage" RELATED [GOC:dph, GOC:tb]
-is_a: GO:0001545 ! primary ovarian follicle growth
-intersection_of: GO:0001545 ! primary ovarian follicle growth
-intersection_of: part_of GO:0048161 ! double layer follicle stage
-relationship: part_of GO:0048161 ! double layer follicle stage
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001545
+consider: GO:0048161
[Term]
id: GO:0043930
-name: primary ovarian follicle growth involved in primary follicle stage
+name: obsolete primary ovarian follicle growth involved in primary follicle stage
namespace: biological_process
-def: "Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle) as part of the primary follicle stage of oogenesis." [GOC:mtg_mpo]
+def: "OBSOLETE. Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle) as part of the primary follicle stage of oogenesis." [GOC:mtg_mpo]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "primary ovarian follicle growth during primary follicle stage" RELATED [GOC:dph, GOC:tb]
-is_a: GO:0001545 ! primary ovarian follicle growth
-intersection_of: GO:0001545 ! primary ovarian follicle growth
-intersection_of: part_of GO:0048160 ! primary follicle stage
-relationship: part_of GO:0048160 ! primary follicle stage
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001545
+consider: GO:0048160
[Term]
id: GO:0043931
@@ -258784,6 +267431,9 @@
xref: RHEA:26534
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.36
+property_value: skos:exactMatch RHEA:26534
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043956
@@ -258801,6 +267451,9 @@
xref: MetaCyc:RXN-6383
xref: RHEA:26518
is_a: GO:0004300 ! enoyl-CoA hydratase activity
+property_value: skos:exactMatch EC:4.2.1.116
+property_value: skos:exactMatch RHEA:26518
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043957
@@ -258819,7 +267472,10 @@
xref: MetaCyc:RXN-9087
xref: RHEA:26454
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.84
+property_value: skos:exactMatch RHEA:26454
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043958
@@ -258835,7 +267491,10 @@
xref: MetaCyc:RXN-8568
xref: RHEA:34471
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.95
+property_value: skos:exactMatch RHEA:34471
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23497" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043959
@@ -258845,6 +267504,8 @@
synonym: "HpcH/HpaI aldolase" RELATED []
xref: RHEA:38259
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:broadMatch EC:4.1.3.24
+property_value: skos:exactMatch RHEA:38259
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
[Term]
@@ -258866,6 +267527,9 @@
xref: MetaCyc:RXN-8966
xref: RHEA:38279
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.20
+property_value: skos:exactMatch RHEA:38279
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0043962
@@ -259191,6 +267855,7 @@
synonym: "histone H3-K9 acetyltransferase activity" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H3-K9 specific)" EXACT []
is_a: GO:0010484 ! histone H3 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -259207,6 +267872,7 @@
synonym: "histone H3-K18 acetyltransferase activity" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H3-K18 specific)" EXACT []
is_a: GO:0010484 ! histone H3 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -259223,6 +267889,7 @@
synonym: "histone H3-K23 acetyltransferase activity" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H3-K23 specific)" EXACT []
is_a: GO:0010484 ! histone H3 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -259238,6 +267905,7 @@
synonym: "histone acetyltransferase activity (H4-K5 specific)" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H4-K5 specific)" EXACT []
is_a: GO:0010485 ! histone H4 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -259253,6 +267921,7 @@
synonym: "histone acetyltransferase activity (H4-K8 specific)" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H4-K8 specific)" EXACT []
is_a: GO:0010485 ! histone H4 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -259269,6 +267938,7 @@
synonym: "histone H4-K12 acetyltransferase activity" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H4-K12 specific)" EXACT []
is_a: GO:0010485 ! histone H4 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -259283,6 +267953,7 @@
synonym: "H2A histone acetyltransferase activity" EXACT []
synonym: "H2A histone lysine N-acetyltransferase activity" EXACT []
is_a: GO:0004402 ! histone acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -259297,6 +267968,7 @@
synonym: "histone H2A-K5 acetyltransferase activity" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H2A-K5 specific)" EXACT []
is_a: GO:0043998 ! histone H2A acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23793" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -259425,6 +268097,7 @@
synonym: "histone H2A-K9 acetyltransferase activity" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H2A-K9 specific)" EXACT []
is_a: GO:0043998 ! histone H2A acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23793" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -259440,6 +268113,7 @@
synonym: "H2B histone acetyltransferase activity" EXACT []
synonym: "H2B histone lysine N-acetyltransferase activity" EXACT []
is_a: GO:0004402 ! histone acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -259453,6 +268127,7 @@
synonym: "histone acetyltransferase activity (H2B-K5 specific)" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H2B-K5 specific)" EXACT []
is_a: GO:0044013 ! histone H2B acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -259469,6 +268144,7 @@
synonym: "histone H2B-K12 acetyltransferase activity" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H2B-K12 specific)" EXACT []
is_a: GO:0044013 ! histone H2B acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -259485,6 +268161,7 @@
synonym: "histone H3-K4 acetyltransferase activity" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H3-K4 specific)" EXACT []
is_a: GO:0010484 ! histone H3 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -259501,6 +268178,7 @@
synonym: "histone H3-K27 acetyltransferase activity" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H3-K27 specific)" EXACT []
is_a: GO:0010484 ! histone H3 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -259517,6 +268195,7 @@
synonym: "histone H3-K36 acetyltransferase activity" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H3-K36 specific)" EXACT []
is_a: GO:0010484 ! histone H3 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -259548,6 +268227,9 @@
synonym: "histone-arginine N-methyltransferase activity (H4-R3 specific)" EXACT []
is_a: GO:0016274 ! protein-arginine N-methyltransferase activity
is_a: GO:0140939 ! histone H4 methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.319
+property_value: skos:broadMatch EC:2.1.1.320
+property_value: skos:broadMatch RHEA:48108
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -259562,6 +268244,7 @@
synonym: "histone-serine kinase activity (H3-S28 specific)" EXACT []
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0140996 ! histone H3 kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -259576,6 +268259,7 @@
synonym: "histone-serine kinase activity (H4-S1 specific)" EXACT []
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0140997 ! histone H4 kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -259589,6 +268273,7 @@
synonym: "histone-serine kinase activity (H2A-S1 specific)" EXACT []
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0140995 ! histone H2A kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28340" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -259603,6 +268288,7 @@
synonym: "histone-serine kinase activity (H2B-S14 specific)" EXACT []
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0140998 ! histone H2B kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -260407,6 +269093,9 @@
xref: MetaCyc:RXN-13231
xref: RHEA:38275
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.46
+property_value: skos:exactMatch RHEA:38275
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2009-07-09T03:14:15Z
@@ -260428,6 +269117,8 @@
def: "Catalysis of the reaction: L-arabinose + NADP+ = L-arabinono-1,4-lactone + NADPH + H+." [GOC:jl, PMID:16326697]
xref: EC:1.1.1.376
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.376
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2009-07-09T04:00:30Z
@@ -260450,8 +269141,11 @@
xref: MetaCyc:RXN-11825
xref: RHEA:68100
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.1.1.15
+property_value: skos:exactMatch RHEA:68100
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21874" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2009-07-09T04:25:43Z
@@ -261833,16 +270527,18 @@
[Term]
id: GO:0044250
-name: negative regulation of metabolic activity involved in hibernation
+name: obsolete negative regulation of metabolic activity involved in hibernation
namespace: biological_process
-def: "The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation." [GOC:jl, Wikipedia:Hibernation]
+def: "OBSOLETE. The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation." [GOC:jl, Wikipedia:Hibernation]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of metabolic activity during hibernation" RELATED []
synonym: "down-regulation of metabolic activity during hibernation" RELATED []
synonym: "downregulation of metabolic activity during hibernation" RELATED []
synonym: "inhibition of metabolic activity during hibernation" NARROW []
synonym: "negative regulation of metabolic activity during hibernation" RELATED [GOC:tb]
-is_a: GO:0009892 ! negative regulation of metabolic process
-relationship: part_of GO:0042750 ! hibernation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0042750
[Term]
id: GO:0044251
@@ -263139,7 +271835,7 @@
namespace: biological_process
def: "The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus." [GOC:BHF, PMID:19079291]
synonym: "cellular glucose import in response to insulin stimulus" EXACT []
-is_a: GO:0046323 ! D-glucose import
+is_a: GO:0098708 ! D-glucose import across plasma membrane
relationship: part_of GO:0032869 ! cellular response to insulin stimulus
created_by: jl
creation_date: 2011-12-08T02:44:01Z
@@ -264781,11 +273477,15 @@
id: GO:0044523
name: venom-mediated disruption of extracellular matrix in another organism
namespace: biological_process
-def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, damaging the extracellular matrix of a cell." [GOC:fj, GOC:jl, PMID:20398688, PMID:21150580, PMID:33460638]
+def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, damaging the extracellular matrix of a cell." [GOC:fj, GOC:jl, PMID:20398688, PMID:21150580, PMID:33460638, PMID:37006255, PMID:41241197]
synonym: "envenomation resulting in damage of muscle extracellular matrix causing muscle necrosis in other organism" NARROW []
synonym: "envenomation resulting in damage of muscle extracellular matrix in another organism" NARROW []
synonym: "envenomation resulting in damage of muscle extracellular matrix in other organism" NARROW []
+synonym: "venom spreading factor" RELATED []
+synonym: "venom-mediated extracellular matrix disassembly" EXACT []
+synonym: "venom-mediated extracellular matrix disassembly enhancing venom spread" NARROW []
is_a: GO:0140138 ! venom-mediated disruption of anatomical structure in another organism
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31166" xsd:anyURI
created_by: jl
creation_date: 2012-02-27T12:40:32Z
@@ -264910,8 +273610,10 @@
synonym: "VLC fatty-acyl-CoA oxidase activity" EXACT []
xref: RHEA:78847
is_a: GO:0003997 ! acyl-CoA oxidase activity
+property_value: skos:exactMatch RHEA:78847
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24703" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28733" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-03-21T02:04:42Z
@@ -264963,14 +273665,18 @@
[Term]
id: GO:0044540
-name: L-cystine L-cysteine-lyase (deaminating)
+name: L-cystine L-cysteine-lyase (deaminating) activity
namespace: molecular_function
-def: "Catalysis of the reaction: L-cystine + H2O = pyruvate + NH3 + thiocysteine. Thiocysteine is also known as cysteine persulfide." [GOC:jl, RHEA:24927]
+def: "Catalysis of the reaction: L-cystine + H2O = pyruvate + NH3 + thiocysteine. Thiocysteine is also known as cysteine persulfide." [RHEA:24927]
xref: EC:4.4.1.35
xref: KEGG_REACTION:R02408
xref: RHEA:24927
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:broadMatch EC:4.4.1.1
+property_value: skos:exactMatch EC:4.4.1.35
+property_value: skos:exactMatch RHEA:24927
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-03-22T11:33:32Z
@@ -265406,16 +274112,17 @@
[Term]
id: GO:0044577
-name: D-xylose catabolic process to ethanol
+name: D-xylose fermentation
namespace: biological_process
-def: "The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, into ethanol." [DOI:10.1016/0141-0229(89)90098-7, GOC:mengo_curators, GOC:tt, PMID:26927067]
-synonym: "D-xylose fermentation" EXACT []
+def: "The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, into ethanol." [GOC:mengo_curators, GOC:tt, PMID:26927067, PMID:30448678]
+synonym: "D-xylose catabolic process to ethanol" EXACT []
synonym: "xylose catabolism to ethanol" EXACT []
is_a: GO:0006067 ! ethanol metabolic process
is_a: GO:0006113 ! fermentation
is_a: GO:0042843 ! D-xylose catabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28614" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31218" xsd:anyURI
created_by: jl
creation_date: 2012-04-19T03:50:46Z
@@ -265590,8 +274297,10 @@
def: "Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+." [PMID:17074428, RHEA:81599]
xref: RHEA:81599
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:81599
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21791" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29321" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-04-26T04:49:13Z
@@ -265713,7 +274422,6 @@
synonym: "phytochelatin transmembrane transporter activity" RELATED []
synonym: "phytochelatin transmembrane transporter ATPase activity" RELATED []
synonym: "phytochelatin transporter activity" RELATED []
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
relationship: part_of GO:0061687 ! detoxification of inorganic compound
relationship: part_of GO:0071994 ! phytochelatin transmembrane transport
@@ -266422,7 +275130,9 @@
is_a: GO:0015297 ! antiporter activity
is_a: GO:1901235 ! (R)-carnitine transmembrane transporter activity
is_a: GO:1901236 ! 4-(trimethylammonio)butanoate transmembrane transporter activity
+property_value: skos:exactMatch RHEA:29427
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-08-08T11:17:12Z
@@ -266434,6 +275144,8 @@
xref: RHEA:33135
is_a: GO:0017153 ! sodium:dicarboxylate symporter activity
is_a: GO:1901239 ! malonate(1-) transmembrane transporter activity
+property_value: skos:exactMatch RHEA:33135
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-08-08T11:59:48Z
@@ -266574,7 +275286,10 @@
xref: EC:3.5.4.39
xref: RHEA:25860
is_a: GO:0003933 ! GTP cyclohydrolase activity
+property_value: skos:exactMatch EC:3.5.4.39
+property_value: skos:exactMatch RHEA:25860
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26710" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-08-15T11:18:40Z
@@ -266589,6 +275304,9 @@
xref: MetaCyc:RXN-8125
xref: RHEA:32667
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.251
+property_value: skos:exactMatch RHEA:32667
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-08-15T11:41:24Z
@@ -266601,6 +275319,9 @@
xref: RHEA:42804
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
relationship: part_of GO:2001118 ! tetrahydromethanopterin biosynthetic process
+property_value: skos:exactMatch EC:1.5.99.15
+property_value: skos:exactMatch RHEA:42804
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-08-15T13:57:55Z
@@ -266624,6 +275345,9 @@
xref: MetaCyc:RXN-11108
xref: RHEA:26486
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.76
+property_value: skos:exactMatch RHEA:26486
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-08-15T14:16:05Z
@@ -266637,6 +275361,8 @@
xref: MetaCyc:RXN-8813
xref: RHEA:25694
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.81
+property_value: skos:exactMatch RHEA:25694
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
created_by: jl
@@ -266662,7 +275388,10 @@
xref: MetaCyc:RXN-19230
xref: RHEA:55204
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.32
+property_value: skos:exactMatch RHEA:55204
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25983" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-08-15T14:33:17Z
@@ -266802,6 +275531,8 @@
xref: Reactome:R-HSA-2395879 "NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP"
xref: RHEA:32063
is_a: GO:0017110 ! nucleoside diphosphate phosphatase activity
+property_value: skos:broadMatch EC:3.6.1.58
+property_value: skos:exactMatch RHEA:32063
created_by: jl
creation_date: 2012-10-18T13:31:09Z
@@ -266813,6 +275544,8 @@
xref: Reactome:R-HSA-2395873 "NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP"
xref: RHEA:62356
is_a: GO:0017110 ! nucleoside diphosphate phosphatase activity
+property_value: skos:broadMatch EC:3.6.1.58
+property_value: skos:exactMatch RHEA:62356
created_by: jl
creation_date: 2012-10-18T13:32:39Z
@@ -267779,10 +276512,14 @@
namespace: biological_process
def: "The anaerobic metabolic process in which pyruvate is converted to acetyl-CoA and formate by the action of pyruvate formate lyase (PFL), typically occurring in facultative anaerobic bacteria during mixed-acid fermentation." [PMID:19752030, PMID:2248795]
synonym: "glycolytic fermentation via PFL pathway" RELATED []
+xref: MetaCyc:PWY-5480
+xref: MetaCyc:PWY-5485
is_a: GO:0019660 ! pyruvate fermentation
intersection_of: GO:0019660 ! pyruvate fermentation
intersection_of: has_part GO:0008861 ! formate C-acetyltransferase activity
relationship: has_part GO:0008861 ! formate C-acetyltransferase activity
+property_value: skos:narrowMatch MetaCyc:PWY-5480
+property_value: skos:narrowMatch MetaCyc:PWY-5485
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29511" xsd:anyURI
created_by: jl
creation_date: 2013-09-18T16:56:02Z
@@ -268473,7 +277210,10 @@
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
relationship: part_of GO:0052704 ! ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide
+property_value: skos:exactMatch EC:1.14.99.50
+property_value: skos:exactMatch RHEA:42672
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/11163" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2014-12-15T11:44:54Z
@@ -268945,7 +277685,7 @@
synonym: "protein transport into mitochondrial intermembrane space" EXACT []
is_a: GO:0070585 ! protein localization to mitochondrion
is_a: GO:0071806 ! protein transmembrane transport
-is_a: GO:0072655 ! establishment of protein localization to mitochondrion
+is_a: GO:0072594 ! establishment of protein localization to organelle
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29962" xsd:anyURI
[Term]
@@ -269674,7 +278414,6 @@
name: bioactive lipid receptor activity
namespace: molecular_function
def: "Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes." [GOC:bf, GOC:mah, PMID:12215548, PMID:18216770]
-xref: Reactome:R-HSA-400434 "FFAR1 binds fatty acids"
is_a: GO:0004930 ! G protein-coupled receptor activity
[Term]
@@ -269694,7 +278433,10 @@
xref: Reactome:R-HSA-6803771 "NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P"
xref: RHEA:17417
is_a: GO:0019200 ! carbohydrate kinase activity
+property_value: skos:exactMatch EC:2.7.1.59
+property_value: skos:exactMatch RHEA:17417
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27926" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045128
@@ -269737,9 +278479,11 @@
synonym: "keratan sulphotransferase activity" EXACT []
xref: EC:2.8.2.21
xref: MetaCyc:KERATAN-SULFOTRANSFERASE-RXN
-xref: Reactome:R-HSA-2046175 "CHST1 transfers sulfate to Gal on keratan chain"
+xref: Reactome:R-HSA-2046175 "Further sulfation on galactose residues produces KSPG"
is_a: GO:0050698 ! proteoglycan sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.21
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28380" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045131
@@ -269774,6 +278518,9 @@
xref: MetaCyc:1.13.11.14-RXN
xref: RHEA:18477
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.14
+property_value: skos:exactMatch RHEA:18477
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045134
@@ -269789,7 +278536,9 @@
xref: MetaCyc:RXN-12197
xref: RHEA:64876
is_a: GO:0017110 ! nucleoside diphosphate phosphatase activity
+property_value: skos:exactMatch RHEA:64876
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045135
@@ -269805,6 +278554,8 @@
xref: EC:4.2.2.3
xref: MetaCyc:4.2.2.3-RXN
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.3
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045136
@@ -269812,6 +278563,8 @@
namespace: biological_process
def: "The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion." [GOC:ai]
is_a: GO:0003006 ! developmental process involved in reproduction
+relationship: part_of GO:0007275 ! multicellular organism development
+relationship: part_of GO:0007548 ! sex differentiation
[Term]
id: GO:0045137
@@ -269851,6 +278604,8 @@
xref: EC:2.7.1.227
xref: MetaCyc:RXN3O-581
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.7.1.227
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045141
@@ -269905,7 +278660,9 @@
xref: EC:3.1.11.4
is_a: GO:0008297 ! single-stranded DNA exodeoxyribonuclease activity
is_a: GO:0035312 ! 5'-3' DNA exonuclease activity
+property_value: skos:exactMatch EC:3.1.11.4
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26645" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045146
@@ -269945,7 +278702,9 @@
xref: MetaCyc:3.4.11.4-RXN
is_a: GO:0004177 ! aminopeptidase activity
is_a: GO:0034701 ! tripeptidase activity
+property_value: skos:exactMatch EC:3.4.11.4
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19681" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045149
@@ -270187,7 +278946,10 @@
is_a: GO:0015038 ! glutathione disulfide oxidoreductase activity
is_a: GO:0016209 ! antioxidant activity
is_a: GO:0016672 ! oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.8.5.1
+property_value: skos:exactMatch RHEA:24424
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23325" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045175
@@ -271444,6 +280206,7 @@
xref: EC:1.1.1.117
xref: MetaCyc:1.1.1.117-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.117
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -271536,7 +280299,10 @@
xref: MetaCyc:RXN-7903
xref: RHEA:11776
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.2
+property_value: skos:exactMatch RHEA:11776
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22382" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045301
@@ -271551,6 +280317,8 @@
xref: RHEA:65812
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:1.14.99.69
+property_value: skos:exactMatch RHEA:65812
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
[Term]
@@ -271566,6 +280334,9 @@
xref: MetaCyc:CHOLOYLGLYCINE-HYDROLASE-RXN
xref: RHEA:19353
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.24
+property_value: skos:exactMatch RHEA:19353
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045303
@@ -271587,6 +280358,9 @@
xref: MetaCyc:R101-RXN
xref: RHEA:11160
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.76
+property_value: skos:exactMatch RHEA:11160
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045304
@@ -272181,6 +280955,8 @@
xref: EC:5.5.1.6
xref: MetaCyc:CHALCONE-ISOMERASE-RXN
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.6
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045431
@@ -272194,6 +280970,9 @@
xref: RHEA:21088
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
relationship: part_of GO:0051555 ! flavonol biosynthetic process
+property_value: skos:exactMatch EC:1.14.20.6
+property_value: skos:exactMatch RHEA:21088
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045433
@@ -272238,6 +281017,8 @@
xref: RHEA:32219
is_a: GO:0009975 ! cyclase activity
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:exactMatch RHEA:32219
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045437
@@ -272251,6 +281032,9 @@
xref: MetaCyc:URIDINE-NUCLEOSIDASE-RXN
xref: RHEA:15577
is_a: GO:0050263 ! ribosylpyrimidine nucleosidase activity
+property_value: skos:exactMatch EC:3.2.2.3
+property_value: skos:exactMatch RHEA:15577
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045438
@@ -272275,6 +281059,9 @@
xref: MetaCyc:5.1.1.17-RXN
xref: RHEA:20033
is_a: GO:0016855 ! racemase and epimerase activity, acting on amino acids and derivatives
+property_value: skos:exactMatch EC:5.1.1.17
+property_value: skos:exactMatch RHEA:20033
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045442
@@ -272293,6 +281080,9 @@
xref: MetaCyc:1.14.11.26-RXN
xref: RHEA:16805
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.26
+property_value: skos:exactMatch RHEA:16805
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045443
@@ -272639,6 +281429,9 @@
xref: MetaCyc:GALACTOSE-OXIDASE-RXN
xref: RHEA:24160
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.9
+property_value: skos:exactMatch RHEA:24160
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045481
@@ -272651,6 +281444,9 @@
xref: MetaCyc:6-ENDO-HYDROXYCINEOLE-DEHYDROGENASE-RXN
xref: RHEA:11736
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.241
+property_value: skos:exactMatch RHEA:11736
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045482
@@ -272666,6 +281462,9 @@
xref: MetaCyc:TRICHODIENE-SYNTHASE-RXN
xref: RHEA:12052
is_a: GO:0010334 ! sesquiterpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.6
+property_value: skos:exactMatch RHEA:12052
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045483
@@ -272680,6 +281479,9 @@
xref: MetaCyc:ARISTOLOCHENE-SYNTHASE-RXN
xref: RHEA:19825
is_a: GO:0010334 ! sesquiterpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.9
+property_value: skos:exactMatch RHEA:19825
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045484
@@ -272700,6 +281502,9 @@
xref: MetaCyc:L-LYSINE-AMINOTRANSFERASE-RXN
xref: RHEA:21200
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.36
+property_value: skos:exactMatch RHEA:21200
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045485
@@ -272728,6 +281533,9 @@
xref: MetaCyc:1.14.11.9-RXN
xref: RHEA:18621
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.9
+property_value: skos:exactMatch MetaCyc:1.14.11.9-RXN
+property_value: skos:exactMatch RHEA:18621
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -273132,7 +281940,10 @@
synonym: "gibberellin 2beta-dioxygenase activity" RELATED [EC:1.14.11.13]
synonym: "gibberellin 2beta-hydroxylase activity" RELATED [EC:1.14.11.13]
xref: EC:1.14.11.13
+xref: RHEA:15005
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.13
+property_value: skos:narrowMatch RHEA:15005
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22382" xsd:anyURI
[Term]
@@ -273140,7 +281951,19 @@
name: gibberellin 20-oxidase activity
namespace: molecular_function
def: "Catalysis of the reaction: 2 2-oxoglutarate + gibberellin A12 (GA12) + H+ + 3 O2 = 3 CO2 + gibberellin A9 (GA9) + 2 H2O + 2 succinate. This reaction results in the oxidation of C-20 gibberellins to form the corresponding C-19 lactones, via a three-step oxidation at C-20 of the GA skeleton. Also converts GA53 to GA20. GA25 is also formed as a minor product." [PMID:32652020, PMID:7604047]
+xref: RHEA:60768
+xref: RHEA:60772
+xref: RHEA:60776
+xref: RHEA:60780
+xref: RHEA:60796
+xref: RHEA:60800
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:narrowMatch RHEA:60768
+property_value: skos:narrowMatch RHEA:60772
+property_value: skos:narrowMatch RHEA:60776
+property_value: skos:narrowMatch RHEA:60780
+property_value: skos:narrowMatch RHEA:60796
+property_value: skos:narrowMatch RHEA:60800
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28852" xsd:anyURI
[Term]
@@ -273159,9 +281982,12 @@
xref: EC:2.5.1.87
xref: RHEA:53008
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.87
+property_value: skos:exactMatch RHEA:53008
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25050" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045548
@@ -273176,6 +282002,9 @@
xref: EC:4.3.1.24
xref: RHEA:21384
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:broadMatch EC:4.3.1.25
+property_value: skos:exactMatch EC:4.3.1.24
+property_value: skos:exactMatch RHEA:21384
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
[Term]
@@ -273192,6 +282021,8 @@
synonym: "VP14" RELATED [EC:1.13.11.51]
xref: EC:1.13.11.51
is_a: GO:0010436 ! carotenoid dioxygenase activity
+property_value: skos:exactMatch EC:1.13.11.51
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045550
@@ -273209,8 +282040,20 @@
synonym: "cinnamyl alcohol dehydrogenase activity" RELATED [EC:1.1.1.195]
synonym: "cinnamyl-alcohol:NADP+ oxidoreductase activity" RELATED [EC:1.1.1.195]
xref: EC:1.1.1.195
+xref: KEGG_REACTION:R03918
xref: MetaCyc:CINNAMYL-ALCOHOL-DEHYDROGENASE-RXN
+xref: MetaCyc:RXN-1125
+xref: RHEA:10392
+xref: RHEA:45704
+xref: RHEA:45724
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.195
+property_value: skos:exactMatch MetaCyc:CINNAMYL-ALCOHOL-DEHYDROGENASE-RXN
+property_value: skos:narrowMatch KEGG_REACTION:R03918
+property_value: skos:narrowMatch MetaCyc:RXN-1125
+property_value: skos:narrowMatch RHEA:10392
+property_value: skos:narrowMatch RHEA:45704
+property_value: skos:narrowMatch RHEA:45724
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -273229,7 +282072,10 @@
xref: MetaCyc:RXN-17678
xref: RHEA:54444
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.219
+property_value: skos:exactMatch RHEA:54444
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30173" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0045557
@@ -280249,6 +289095,9 @@
xref: MetaCyc:2.1.1.132-RXN
xref: RHEA:17477
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.132
+property_value: skos:exactMatch RHEA:17477
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046026
@@ -280261,6 +289110,9 @@
xref: MetaCyc:2.1.1.133-RXN
xref: RHEA:22012
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.133
+property_value: skos:exactMatch RHEA:22012
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046027
@@ -280273,6 +289125,9 @@
xref: MetaCyc:2.3.1.158-RXN
xref: RHEA:14057
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.158
+property_value: skos:exactMatch RHEA:14057
+property_value: skos:relatedMatch RHEA:77739
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29862" xsd:anyURI
[Term]
@@ -280299,6 +289154,9 @@
xref: RHEA:15029
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
is_a: GO:0031320 ! hexitol dehydrogenase activity
+property_value: skos:exactMatch EC:1.1.1.255
+property_value: skos:exactMatch RHEA:15029
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046030
@@ -282478,7 +291336,6 @@
def: "The chemical reactions and pathways involving bacteriocins, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary." [GOC:ai]
synonym: "bacteriocin metabolism" EXACT []
is_a: GO:0009404 ! toxin metabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0046225
@@ -283463,7 +292320,6 @@
synonym: "2-chloro-N-isopropylacetanilide degradation" EXACT []
is_a: GO:0009056 ! catabolic process
is_a: GO:0042537 ! benzene-containing compound metabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0090345 ! organohalogen metabolic process
[Term]
@@ -283578,28 +292434,28 @@
[Term]
id: GO:0046312
-name: phosphoarginine biosynthetic process
+name: obsolete phosphoarginine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of phosphoarginine, a phosphorylated derivative of the amino acid arginine." [GOC:ai]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of phosphoarginine, a phosphorylated derivative of the amino acid arginine." [GOC:ai]
+comment: The reason for obsoletion is that this represents a molecular function.
synonym: "phosphoarginine anabolism" EXACT []
synonym: "phosphoarginine biosynthesis" EXACT []
synonym: "phosphoarginine formation" EXACT []
synonym: "phosphoarginine synthesis" EXACT []
-is_a: GO:0042396 ! phosphagen biosynthetic process
-is_a: GO:0170034 ! L-amino acid biosynthetic process
-is_a: GO:0170043 ! non-proteinogenic amino acid biosynthetic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31091" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0046313
-name: phosphoarginine catabolic process
+name: obsolete phosphoarginine catabolic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of phosphoarginine, a phosphorylated derivative of the amino acid arginine." [GOC:ai]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of phosphoarginine, a phosphorylated derivative of the amino acid arginine." [GOC:ai]
+comment: The reason for obsoletion is that this represents a molecular function.
synonym: "phosphoarginine breakdown" EXACT []
synonym: "phosphoarginine catabolism" EXACT []
synonym: "phosphoarginine degradation" EXACT []
-is_a: GO:0042397 ! phosphagen catabolic process
-is_a: GO:0170035 ! L-amino acid catabolic process
-is_a: GO:0170044 ! non-proteinogenic amino acid catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31091" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0046314
@@ -283638,6 +292494,9 @@
xref: RHEA:19433
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.12
+property_value: skos:exactMatch RHEA:19433
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046317
@@ -283735,31 +292594,35 @@
[Term]
id: GO:0046323
-name: D-glucose import
+name: obsolete D-glucose import
namespace: biological_process
-def: "The directed movement of the hexose monosaccharide D-glucose into a cell or organelle." [GOC:ai]
+def: "OBSOLETE. The directed movement of the hexose monosaccharide D-glucose into a cell or organelle." [GOC:ai]
+comment: The reason for obsoletion is that this term is equivalent to D-glucose import across plasma membrane.
synonym: "glucose import" EXACT []
synonym: "glucose uptake" EXACT [GOC:dph, GOC:tb]
xref: Wikipedia:Glucose_uptake
-is_a: GO:1904659 ! D-glucose transmembrane transport
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30861" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0098708
[Term]
id: GO:0046324
-name: regulation of D-glucose import
+name: regulation of D-glucose import across plasma membrane
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle." [GOC:ai]
+def: "Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell." [GOC:ai]
synonym: "regulation of glucose import" EXACT []
synonym: "regulation of glucose uptake" EXACT [GOC:dph, GOC:tb]
is_a: GO:0010827 ! regulation of D-glucose transmembrane transport
intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0046323 ! D-glucose import
-relationship: regulates GO:0046323 ! D-glucose import
+intersection_of: regulates GO:0098708 ! D-glucose import across plasma membrane
+relationship: regulates GO:0098708 ! D-glucose import across plasma membrane
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30861" xsd:anyURI
[Term]
id: GO:0046325
-name: negative regulation of D-glucose import
+name: negative regulation of D-glucose import across plasma membrane
namespace: biological_process
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle." [GOC:ai]
+def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell." [GOC:ai]
synonym: "down regulation of glucose import" EXACT []
synonym: "down-regulation of glucose import" EXACT []
synonym: "downregulation of glucose import" EXACT []
@@ -283767,16 +292630,17 @@
synonym: "negative regulation of glucose import" EXACT []
synonym: "negative regulation of glucose uptake" EXACT [GOC:dph, GOC:tb]
is_a: GO:0010829 ! negative regulation of D-glucose transmembrane transport
-is_a: GO:0046324 ! regulation of D-glucose import
+is_a: GO:0046324 ! regulation of D-glucose import across plasma membrane
intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0046323 ! D-glucose import
-relationship: negatively_regulates GO:0046323 ! D-glucose import
+intersection_of: negatively_regulates GO:0098708 ! D-glucose import across plasma membrane
+relationship: negatively_regulates GO:0098708 ! D-glucose import across plasma membrane
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30861" xsd:anyURI
[Term]
id: GO:0046326
-name: positive regulation of D-glucose import
+name: positive regulation of D-glucose import across plasma membrane
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle." [GOC:ai, GOC:dph, GOC:tb]
+def: "Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell." [GOC:ai, GOC:dph, GOC:tb]
synonym: "activation of glucose import" NARROW []
synonym: "positive regulation of glucose import" EXACT []
synonym: "positive regulation of glucose uptake" EXACT [GOC:dph, GOC:tb]
@@ -283785,10 +292649,11 @@
synonym: "up-regulation of glucose import" EXACT []
synonym: "upregulation of glucose import" EXACT []
is_a: GO:0010828 ! positive regulation of D-glucose transmembrane transport
-is_a: GO:0046324 ! regulation of D-glucose import
+is_a: GO:0046324 ! regulation of D-glucose import across plasma membrane
intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0046323 ! D-glucose import
-relationship: positively_regulates GO:0046323 ! D-glucose import
+intersection_of: positively_regulates GO:0098708 ! D-glucose import across plasma membrane
+relationship: positively_regulates GO:0098708 ! D-glucose import across plasma membrane
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30861" xsd:anyURI
[Term]
id: GO:0046327
@@ -284103,10 +292968,19 @@
synonym: "gentamicin-(3)-N-acetyltransferase activity" NARROW [EC:2.3.1.81]
synonym: "gentamycin 3-N-acetyltransferase activity" EXACT []
synonym: "gentamycin acetyltransferase I" RELATED [EC:2.3.1.60]
+xref: EC:2.3.1.60
xref: EC:2.3.1.81
xref: MetaCyc:AMINOGLYCOSIDE-N3-ACETYLTRANSFERASE-RXN
+xref: MetaCyc:GENTAMICIN-3-N-ACETYLTRANSFERASE-RXN
xref: RHEA:12665
+xref: RHEA:14441
is_a: GO:0034069 ! aminoglycoside N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.81
+property_value: skos:exactMatch MetaCyc:AMINOGLYCOSIDE-N3-ACETYLTRANSFERASE-RXN
+property_value: skos:exactMatch RHEA:12665
+property_value: skos:narrowMatch EC:2.3.1.60
+property_value: skos:narrowMatch MetaCyc:GENTAMICIN-3-N-ACETYLTRANSFERASE-RXN
+property_value: skos:narrowMatch RHEA:14441
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29522" xsd:anyURI
@@ -284424,7 +293298,6 @@
synonym: "N-acetylneuraminate formation" EXACT []
synonym: "N-acetylneuraminate synthesis" EXACT []
is_a: GO:0006054 ! N-acetylneuraminate metabolic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0046349 ! amino sugar biosynthetic process
is_a: GO:0046394 ! carboxylic acid biosynthetic process
@@ -284667,7 +293540,10 @@
xref: Reactome:R-HSA-5649705 "PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB)"
xref: RHEA:14113
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.32
+property_value: skos:exactMatch RHEA:14113
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28000" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046404
@@ -284680,8 +293556,10 @@
xref: MetaCyc:POLYNUCLEOTIDE-5-HYDROXYL-KINASE-RXN
xref: RHEA:15669
is_a: GO:0051734 ! ATP-dependent polynucleotide 5'-hydroxyl-kinase activity
+property_value: skos:exactMatch RHEA:15669
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21619" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25049" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046405
@@ -284695,6 +293573,9 @@
xref: MetaCyc:GLYCEROL-DEHYDRATASE-RXN
xref: RHEA:19765
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.30
+property_value: skos:exactMatch RHEA:19765
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046406
@@ -284715,6 +293596,9 @@
xref: RHEA:17809
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.11
+property_value: skos:exactMatch RHEA:17809
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046408
@@ -284729,6 +293613,9 @@
xref: MetaCyc:RXN1F-66
xref: RHEA:17317
is_a: GO:0004659 ! prenyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.62
+property_value: skos:exactMatch RHEA:17317
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046409
@@ -284854,6 +293741,9 @@
xref: MetaCyc:METHYLISOCITRATE-LYASE-RXN
xref: RHEA:16809
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.30
+property_value: skos:exactMatch RHEA:16809
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046422
@@ -284865,7 +293755,10 @@
xref: EC:1.23.5.1
xref: RHEA:32371
is_a: GO:0120546 ! oxidoreductase activity, reducing C-O-C group as acceptor
+property_value: skos:exactMatch EC:1.23.5.1
+property_value: skos:exactMatch RHEA:32371
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046423
@@ -284879,6 +293772,9 @@
xref: RHEA:22592
is_a: GO:0009975 ! cyclase activity
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:exactMatch EC:5.3.99.6
+property_value: skos:exactMatch RHEA:22592
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046424
@@ -284953,6 +293849,8 @@
xref: MetaCyc:RXN-11047
xref: RHEA:26478
is_a: GO:0004659 ! prenyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.74
+property_value: skos:exactMatch RHEA:26478
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29428" xsd:anyURI
[Term]
@@ -284969,6 +293867,9 @@
xref: MetaCyc:RXN0-882
xref: RHEA:26119
is_a: GO:0052592 ! oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.17.7.1
+property_value: skos:exactMatch RHEA:26119
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046430
@@ -285358,28 +294259,32 @@
[Term]
id: GO:0046466
-name: membrane lipid catabolic process
+name: obsolete membrane lipid catabolic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai]
+comment: The reason for obsoletion is that this term groups lipids by their localization rather than by their metabolic function, which is problematic since most lipids can function in multiple locations.
synonym: "membrane lipid breakdown" EXACT []
synonym: "membrane lipid catabolism" EXACT []
synonym: "membrane lipid degradation" EXACT []
synonym: "membrane lipid peroxidation" BROAD [GOC:tb]
-is_a: GO:0006643 ! membrane lipid metabolic process
-is_a: GO:0016042 ! lipid catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26698" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0016042
[Term]
id: GO:0046467
-name: membrane lipid biosynthetic process
+name: obsolete membrane lipid biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai]
+comment: The reason for obsoletion is that this term groups lipids by their localization rather than by their metabolic function, which is problematic since most lipids can function in multiple locations.
synonym: "membrane lipid anabolism" EXACT []
synonym: "membrane lipid biosynthesis" EXACT []
synonym: "membrane lipid formation" EXACT []
synonym: "membrane lipid synthesis" EXACT []
-is_a: GO:0006643 ! membrane lipid metabolic process
-is_a: GO:0008610 ! lipid biosynthetic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26698" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0008610
[Term]
id: GO:0046468
@@ -285524,6 +294429,9 @@
xref: MetaCyc:RXN-1226
xref: RHEA:15921
is_a: GO:0008378 ! galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.184
+property_value: skos:exactMatch RHEA:15921
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046481
@@ -285543,6 +294451,9 @@
xref: RHEA:10520
xref: Wikipedia:Digalactosyldiacylglycerol_synthase
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.241
+property_value: skos:exactMatch RHEA:10520
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046482
@@ -285822,6 +294733,9 @@
xref: MetaCyc:RXN-1223
xref: RHEA:13197
is_a: GO:0046508 ! hydrolase activity, acting on carbon-sulfur bonds
+property_value: skos:exactMatch EC:3.13.1.1
+property_value: skos:exactMatch RHEA:13197
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046508
@@ -285831,6 +294745,8 @@
synonym: "hydrolase activity, acting on carbon-sulphur bonds" EXACT []
xref: EC:3.13.-.-
is_a: GO:0016787 ! hydrolase activity
+property_value: skos:exactMatch EC:3.13.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046509
@@ -285852,6 +294768,9 @@
xref: MetaCyc:2.4.1.46-RXN
xref: RHEA:14945
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.46
+property_value: skos:exactMatch RHEA:14945
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046510
@@ -285864,6 +294783,8 @@
xref: RHEA:49468
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch RHEA:49468
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046511
@@ -285902,9 +294823,10 @@
synonym: "ceramide biosynthesis" EXACT []
synonym: "ceramide formation" EXACT []
synonym: "ceramide synthesis" EXACT []
+xref: MetaCyc:PWY3DJ-12
is_a: GO:0006672 ! ceramide metabolic process
is_a: GO:0030148 ! sphingolipid biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30616" xsd:anyURI
[Term]
id: GO:0046514
@@ -285997,6 +294919,9 @@
xref: RHEA:22312
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.100
+property_value: skos:exactMatch RHEA:22312
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046523
@@ -286016,10 +294941,13 @@
xref: EC:5.3.1.23
xref: KEGG_REACTION:R04420
xref: MetaCyc:5.3.1.23-RXN
-xref: Reactome:R-HSA-1237096 "Methylthio-ribose-P => Methylthio-ribulose-P"
-xref: Reactome:R-HSA-1299507 "Methylthio-ribulose-P => Methylthio-ribose-P"
+xref: Reactome:R-HSA-1237096 "Methylthio-ribose-P = Methylthio-ribulose-P"
+xref: Reactome:R-HSA-1299507 "Methylthio-ribulose-P = Methylthio-ribose-P"
xref: RHEA:19989
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.23
+property_value: skos:exactMatch RHEA:19989
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046524
@@ -286040,6 +294968,9 @@
xref: MetaCyc:SUCROSE-PHOSPHATE-SYNTHASE-RXN
xref: RHEA:22172
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.14
+property_value: skos:exactMatch RHEA:22172
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046525
@@ -286060,6 +294991,9 @@
xref: RHEA:15297
is_a: GO:0035250 ! UDP-galactosyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.133
+property_value: skos:exactMatch RHEA:15297
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046526
@@ -286074,8 +295008,11 @@
xref: RHEA:20433
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
is_a: GO:0031320 ! hexitol dehydrogenase activity
+property_value: skos:exactMatch EC:1.1.1.9
+property_value: skos:exactMatch RHEA:20433
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21874" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25590" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046527
@@ -286233,6 +295170,9 @@
xref: RHEA:19301
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.8
+property_value: skos:exactMatch RHEA:19301
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046540
@@ -286271,6 +295211,7 @@
namespace: biological_process
def: "The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion." [GOC:ai]
is_a: GO:0045136 ! development of secondary sexual characteristics
+relationship: part_of GO:0046660 ! female sex differentiation
[Term]
id: GO:0046544
@@ -286307,6 +295248,9 @@
xref: MetaCyc:2.1.1.145-RXN
xref: RHEA:22200
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.145
+property_value: skos:exactMatch RHEA:22200
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046548
@@ -286367,6 +295311,9 @@
xref: RHEA:18365
is_a: GO:0016615 ! malate dehydrogenase activity
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.83
+property_value: skos:exactMatch RHEA:18365
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046554
@@ -286385,6 +295332,9 @@
xref: RHEA:10824
is_a: GO:0016615 ! malate dehydrogenase activity
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.82
+property_value: skos:exactMatch RHEA:10824
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046555
@@ -286394,6 +295344,8 @@
xref: EC:3.1.1.72
xref: MetaCyc:3.1.1.72-RXN
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.72
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046556
@@ -286414,6 +295366,8 @@
xref: EC:3.2.1.55
xref: MetaCyc:3.2.1.55-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.55
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046557
@@ -286434,7 +295388,9 @@
xref: EC:3.2.1.75
xref: MetaCyc:3.2.1.75-RXN
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.75
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28262" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046558
@@ -286448,6 +295404,8 @@
xref: EC:3.2.1.99
xref: MetaCyc:3.2.1.99-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.99
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046559
@@ -286460,6 +295418,9 @@
xref: MetaCyc:3.2.1.139-RXN
xref: RHEA:20005
is_a: GO:0046574 ! glucuronidase activity
+property_value: skos:exactMatch EC:3.2.1.139
+property_value: skos:exactMatch RHEA:20005
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30698" xsd:anyURI
[Term]
@@ -286524,7 +295485,10 @@
xref: MetaCyc:GLUCOSE-OXIDASE-RXN
xref: RHEA:11428
is_a: GO:0047979 ! hexose oxidase activity
+property_value: skos:exactMatch EC:1.1.3.4
+property_value: skos:exactMatch RHEA:11428
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046563
@@ -286548,6 +295512,9 @@
xref: MetaCyc:OXALATE-DECARBOXYLASE-RXN
xref: RHEA:16509
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.2
+property_value: skos:exactMatch RHEA:16509
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046565
@@ -286558,6 +295525,9 @@
xref: MetaCyc:DHSHIKIMATE-DEHYDRO-RXN
xref: RHEA:24848
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.118
+property_value: skos:exactMatch RHEA:24848
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046566
@@ -286581,6 +295551,9 @@
xref: MetaCyc:RXN-10631
xref: RHEA:26213
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.42
+property_value: skos:exactMatch RHEA:26213
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046568
@@ -286594,7 +295567,9 @@
xref: EC:1.1.1.265
xref: MetaCyc:1.1.1.265-RXN
is_a: GO:0018455 ! alcohol dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.1.1.265
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046569
@@ -286622,6 +295597,9 @@
xref: Reactome:R-HSA-1237140 "Dehydration of methylthio-ribulose-P"
xref: RHEA:15549
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.109
+property_value: skos:exactMatch RHEA:15549
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046571
@@ -286642,6 +295620,9 @@
xref: MetaCyc:RXN-9494
xref: RHEA:33859
is_a: GO:0016835 ! carbon-oxygen lyase activity
+property_value: skos:exactMatch EC:4.2.1.143
+property_value: skos:exactMatch RHEA:33859
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046573
@@ -286689,6 +295670,9 @@
xref: MetaCyc:RXN-4444
xref: RHEA:22756
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.20
+property_value: skos:exactMatch RHEA:22756
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046578
@@ -286845,8 +295829,11 @@
xref: EC:4.6.1.24
is_a: GO:0004521 ! RNA endonuclease activity
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
+property_value: skos:broadMatch MetaCyc:3.1.27.3-RXN
+property_value: skos:exactMatch EC:4.6.1.24
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24408" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046590
@@ -286876,7 +295863,10 @@
def: "Catalysis of the oxidative degradation or interconversion of polyamines." [PMID:1567380]
synonym: "1-N-acetylspermidine:oxygen oxidoreductase (deaminating)" NARROW []
synonym: "N1-acetylspermidine:oxygen oxidoreductase (deaminating)" NARROW []
+xref: EC:1.5.3.17
is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
+property_value: skos:broadMatch RHEA:25808
+property_value: skos:narrowMatch EC:1.5.3.17
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24701" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25835" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25837" xsd:anyURI
@@ -286897,6 +295887,9 @@
xref: MetaCyc:MANDELONITRILE-LYASE-RXN
xref: RHEA:18313
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.10
+property_value: skos:exactMatch RHEA:18313
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046594
@@ -287236,6 +296229,7 @@
is_a: GO:0046624 ! sphingolipid transporter activity
is_a: GO:0140328 ! floppase activity
relationship: part_of GO:0099039 ! sphingolipid translocation
+property_value: skos:broadMatch RHEA:66132
[Term]
id: GO:0046624
@@ -287669,7 +296663,6 @@
synonym: "vitamin M metabolism" EXACT []
xref: Reactome:R-HSA-196757 "Metabolism of folate and pterines"
is_a: GO:0006760 ! folic acid-containing compound metabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0043648 ! dicarboxylic acid metabolic process
[Term]
@@ -287690,7 +296683,6 @@
xref: Wikipedia:Folic_acid
is_a: GO:0009396 ! folic acid-containing compound biosynthetic process
is_a: GO:0042364 ! water-soluble vitamin biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0043650 ! dicarboxylic acid biosynthetic process
is_a: GO:0046655 ! folic acid metabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
@@ -289201,6 +298193,9 @@
xref: MetaCyc:PABASYN-RXN
xref: RHEA:11672
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.85
+property_value: skos:exactMatch RHEA:11672
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046821
@@ -289639,6 +298634,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces NAD or NADP." [EC:1.7.1.-, GOC:jl]
xref: EC:1.7.1.-
is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors
+property_value: skos:exactMatch EC:1.7.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046858
@@ -290131,6 +299128,9 @@
xref: RHEA:13749
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
is_a: GO:0019205 ! nucleobase-containing compound kinase activity
+property_value: skos:exactMatch EC:2.7.4.10
+property_value: skos:exactMatch RHEA:13749
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046900
@@ -290200,6 +299200,8 @@
xref: RHEA:34475
is_a: GO:0004659 ! prenyltransferase activity
relationship: part_of GO:0016120 ! carotene biosynthetic process
+property_value: skos:exactMatch EC:2.5.1.32
+property_value: skos:exactMatch RHEA:34475
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21165" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29285" xsd:anyURI
@@ -290279,7 +299281,9 @@
synonym: "transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer" EXACT []
xref: EC:2.3.3.-
is_a: GO:0016746 ! acyltransferase activity
+property_value: skos:exactMatch EC:2.3.3.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046914
@@ -290320,6 +299324,9 @@
xref: MetaCyc:2.7.8.25-RXN
xref: RHEA:15117
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.4.2.52
+property_value: skos:exactMatch RHEA:15117
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046918
@@ -290345,7 +299352,7 @@
synonym: "alpha(1,3)-fucosyltransferase activity" EXACT []
synonym: "alpha-(1,3)-fucosyltransferase activity" EXACT []
synonym: "alpha-1,3-fucosyltransferase activity" EXACT []
-xref: Reactome:R-HSA-9603984 "FUT4,5,9 transfer Fuc to Type 2 chains to form LeX"
+xref: Reactome:R-HSA-9603984 "FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX"
xref: Reactome:R-HSA-9605609 "FUT3 transfers Fuc to Type 1 MSGG to form sLeA"
xref: Reactome:R-HSA-9605644 "FUT3 transfers Fuc to Type 1 DSGG to form dsLeA"
xref: Reactome:R-HSA-9605682 "FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX"
@@ -290377,6 +299384,8 @@
is_a: GO:0008417 ! fucosyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
relationship: part_of GO:0036066 ! protein O-linked glycosylation via fucose
+property_value: skos:exactMatch EC:2.4.1.221
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046923
@@ -290485,6 +299494,9 @@
xref: TC:3.A.2.1.2
is_a: GO:0015081 ! sodium ion transmembrane transporter activity
is_a: GO:0016874 ! ligase activity
+property_value: skos:broadMatch EC:7.2.2.1
+property_value: skos:broadMatch MetaCyc:3.6.3.15-RXN
+property_value: skos:exactMatch RHEA:58158
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19380" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21796" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
@@ -290503,6 +299515,9 @@
is_a: GO:0015252 ! proton channel activity
is_a: GO:0016874 ! ligase activity
relationship: part_of GO:0015986 ! proton motive force-driven ATP synthesis
+property_value: skos:broadMatch EC:7.1.2.2
+property_value: skos:broadMatch MetaCyc:ATPSYN-RXN
+property_value: skos:exactMatch RHEA:57722
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19380" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25727" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27850" xsd:anyURI
@@ -290571,7 +299586,10 @@
xref: Reactome:R-HSA-9860816 "Phospho-PI3K in p-Y713-PECAM1:CDH5:PIK3CA,B,D:p-Y464-PIK3R2:p-Y801,Y1054,Y1175-KDR:p-Y1063,Y1230-FLT4:CTNNB1 phosphorylates phosphoinositol-4,5-bisphosphate to yield phosphoinositol-3,4,5-trisphosphate"
xref: RHEA:21292
is_a: GO:0052742 ! phosphatidylinositol kinase activity
+property_value: skos:exactMatch EC:2.7.1.153
+property_value: skos:exactMatch RHEA:21292
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28336" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046935
@@ -290594,6 +299612,8 @@
xref: RHEA:28190
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:broadMatch EC:3.5.4.4
+property_value: skos:exactMatch RHEA:28190
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19833" xsd:anyURI
[Term]
@@ -290604,7 +299624,6 @@
synonym: "cadystin metabolic process" RELATED [GOC:vw, Wikipedia:Phytochelatin#History]
synonym: "cadystin metabolism" RELATED [GOC:vw, Wikipedia:Phytochelatin#History]
synonym: "phytochelatin metabolism" EXACT []
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0044238 ! primary metabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29981" xsd:anyURI
@@ -290618,7 +299637,7 @@
synonym: "phytochelatin biosynthesis" EXACT []
synonym: "phytochelatin formation" EXACT []
synonym: "phytochelatin synthesis" EXACT []
-is_a: GO:0043604 ! amide biosynthetic process
+is_a: GO:0009058 ! biosynthetic process
is_a: GO:0046937 ! phytochelatin metabolic process
[Term]
@@ -290705,15 +299724,15 @@
[Term]
id: GO:0046948
-name: hydroxylysine catabolic process
+name: obsolete hydroxylysine catabolic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the breakdown of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid." [ISBN:0198506732]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid." [ISBN:0198506732]
+comment: The reason for obsoletion is that there is no evidence that this process exists.
synonym: "hydroxylysine breakdown" EXACT []
synonym: "hydroxylysine catabolism" EXACT []
synonym: "hydroxylysine degradation" EXACT []
-is_a: GO:0042219 ! modified amino acid catabolic process
-is_a: GO:0170044 ! non-proteinogenic amino acid catabolic process
-is_a: GO:1901606 ! alpha-amino acid catabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31068" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0046949
@@ -290846,6 +299865,9 @@
is_a: GO:0015078 ! proton transmembrane transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
is_a: GO:0044769 ! ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
+property_value: skos:broadMatch EC:7.1.2.2
+property_value: skos:broadMatch MetaCyc:ATPSYN-RXN
+property_value: skos:exactMatch RHEA:57721
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27850" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
@@ -290874,8 +299896,12 @@
is_a: GO:0015081 ! sodium ion transmembrane transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
is_a: GO:0044769 ! ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
+property_value: skos:broadMatch MetaCyc:3.6.3.15-RXN
+property_value: skos:exactMatch EC:7.2.2.1
+property_value: skos:exactMatch RHEA:58157
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21796" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
@@ -290899,7 +299925,7 @@
synonym: "3'-phosphoadenosine 5'-phosphosulphate transporter activity" EXACT []
synonym: "adenosine 3'-phosphate 5'-phosphosulfate transmembrane transporter activity" EXACT []
synonym: "PAPS transporter activity" EXACT []
-xref: Reactome:R-HSA-741449 "SLC35B2,3 exchange cytosolic PAPS with Golgi PAP"
+xref: Reactome:R-HSA-741449 "SLC35B2,3 transport cytosolic PAPS to Golgi lumen"
is_a: GO:0000295 ! adenine nucleotide transmembrane transporter activity
is_a: GO:0005346 ! purine ribonucleotide transmembrane transporter activity
is_a: GO:1901682 ! sulfur compound transmembrane transporter activity
@@ -290954,6 +299980,7 @@
xref: Reactome:R-HSA-9604829 "SIRT6 deacetylates histones at NOTCH1 and NOTCH4 gene promoters"
is_a: GO:0017136 ! histone deacetylase activity, NAD-dependent
is_a: GO:0141050 ! histone H3K deacetylase activity
+property_value: skos:broadMatch EC:2.3.1.286
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22836" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -290968,6 +299995,7 @@
synonym: "NAD-dependent histone H4K16 deacetylase activity" EXACT []
is_a: GO:0017136 ! histone deacetylase activity, NAD-dependent
is_a: GO:0141051 ! histone H4K deacetylase activity
+property_value: skos:broadMatch EC:2.3.1.286
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22676" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22836" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -290982,6 +300010,7 @@
synonym: "histone acetyltransferase activity (H4-K16 specific)" EXACT []
synonym: "histone lysine acetyltransferase activity (H4-K16 specific)" EXACT []
is_a: GO:0010485 ! histone H4 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -291045,8 +300074,6 @@
synonym: "histone methyltransferase activity (H3-K27 specific)" EXACT []
synonym: "histone-H3K27 methyltransferase activity" EXACT []
xref: Reactome:R-HSA-3240295 "PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter"
-xref: Reactome:R-HSA-9764932 "PRC2 (EZH2) core complex methylates nucleosomes at CDH1 gene promoter"
-xref: Reactome:R-HSA-9909631 "Trimethylation of CD274 gene promoter by EZH2"
is_a: GO:0016279 ! protein-lysine N-methyltransferase activity
is_a: GO:0140938 ! histone H3 methyltransferase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24337" xsd:anyURI
@@ -291201,6 +300228,9 @@
xref: MetaCyc:2.3.1.118-RXN
xref: RHEA:20277
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.118
+property_value: skos:exactMatch RHEA:20277
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046992
@@ -291210,6 +300240,8 @@
synonym: "oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors" NARROW []
xref: EC:1.21.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.21.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046993
@@ -291218,6 +300250,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is oxygen." [GOC:ai]
xref: EC:1.21.3.-
is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond
+property_value: skos:exactMatch EC:1.21.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046994
@@ -291226,6 +300260,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces quinone or similar compound." [GOC:jl]
xref: EC:1.12.5.-
is_a: GO:0016695 ! oxidoreductase activity, acting on hydrogen as donor
+property_value: skos:exactMatch EC:1.12.5.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046995
@@ -291234,6 +300270,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen reduces a known acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP, or a quinone or similar compound." [GOC:ai]
xref: EC:1.12.98.-
is_a: GO:0016695 ! oxidoreductase activity, acting on hydrogen as donor
+property_value: skos:exactMatch EC:1.12.98.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046996
@@ -291252,6 +300290,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a flavin." [GOC:jl]
xref: EC:1.5.8.-
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.8.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046998
@@ -291265,6 +300305,9 @@
xref: MetaCyc:1.1.1.199-RXN
xref: RHEA:21876
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.199
+property_value: skos:exactMatch RHEA:21876
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0046999
@@ -291287,6 +300330,9 @@
xref: MetaCyc:RXN-13040
xref: RHEA:15109
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.126
+property_value: skos:exactMatch RHEA:15109
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047001
@@ -291302,6 +300348,9 @@
xref: MetaCyc:1.1.1.127-RXN
xref: RHEA:24232
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.127
+property_value: skos:exactMatch RHEA:24232
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047002
@@ -291314,6 +300363,9 @@
xref: MetaCyc:1.1.1.13-RXN
xref: RHEA:21356
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.13
+property_value: skos:exactMatch RHEA:21356
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047003
@@ -291329,6 +300381,9 @@
xref: MetaCyc:1.1.1.134-RXN
xref: RHEA:23648
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.134
+property_value: skos:exactMatch RHEA:23648
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047004
@@ -291345,6 +300400,9 @@
xref: MetaCyc:1.1.1.136-RXN
xref: RHEA:13325
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.136
+property_value: skos:exactMatch RHEA:13325
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
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@@ -291372,7 +300430,12 @@
synonym: "20alpha-hydroxysteroid:NAD(P)+ 20-oxidoreductase activity" BROAD [EC:1.1.1.149]
xref: EC:1.1.1.149
xref: MetaCyc:1.1.1.149-RXN
+xref: RHEA:15853
+xref: RHEA:15857
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
id: GO:0047007
@@ -291386,6 +300449,8 @@
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xref: RHEA:11448
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
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@@ -291403,6 +300468,8 @@
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xref: RHEA:23712
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
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@@ -291418,6 +300485,9 @@
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xref: RHEA:10356
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[Term]
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@@ -291432,6 +300502,9 @@
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xref: RHEA:10516
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.166
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[Term]
id: GO:0047011
@@ -291445,7 +300518,10 @@
synonym: "ketopantoyl lactone reductase activity" BROAD [EC:1.1.1.168]
xref: EC:1.1.1.168
is_a: GO:0036441 ! 2-dehydropantolactone reductase activity
+property_value: skos:broadMatch MetaCyc:1.1.1.168-RXN
+property_value: skos:exactMatch EC:1.1.1.168
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
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[Term]
id: GO:0047012
@@ -291475,6 +300551,9 @@
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xref: RHEA:14129
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.176
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[Term]
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@@ -291491,6 +300570,9 @@
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xref: RHEA:19773
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
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@@ -291505,6 +300587,9 @@
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xref: RHEA:13281
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.178
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[Term]
id: GO:0047016
@@ -291519,6 +300604,9 @@
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xref: RHEA:11896
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.181
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[Term]
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@@ -291549,7 +300637,10 @@
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xref: RHEA:10140
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.188
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property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047018
@@ -291564,7 +300655,10 @@
xref: MetaCyc:1.1.1.190-RXN
xref: RHEA:14873
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.190
+property_value: skos:exactMatch RHEA:14873
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
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[Term]
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@@ -291579,6 +300673,9 @@
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xref: RHEA:17037
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
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@@ -291603,6 +300700,9 @@
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xref: RHEA:20744
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.196
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[Term]
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@@ -291619,6 +300719,9 @@
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xref: RHEA:11636
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.197
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[Term]
id: GO:0047022
@@ -291634,6 +300737,9 @@
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xref: Wikipedia:7beta-hydroxysteroid_dehydrogenase_(NADP+)
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.201
+property_value: skos:exactMatch RHEA:20233
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[Term]
id: GO:0047023
@@ -291645,9 +300751,16 @@
synonym: "3(or 17)alpha-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.209]
synonym: "3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase activity" BROAD [EC:1.1.1.209]
xref: EC:1.1.1.209
+xref: RHEA:20377
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is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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+property_value: skos:exactMatch EC:1.1.1.209
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property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29311" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047024
@@ -291667,6 +300780,9 @@
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xref: RHEA:16297
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.210
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[Term]
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@@ -291682,6 +300798,9 @@
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xref: RHEA:19913
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.212
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[Term]
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@@ -291707,6 +300826,9 @@
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xref: RHEA:16405
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.217
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[Term]
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@@ -291723,6 +300845,9 @@
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xref: RHEA:11772
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.220
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[Term]
id: GO:0047029
@@ -291735,6 +300860,7 @@
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xref: RHEA:52692
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:52692
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
@@ -291750,6 +300876,9 @@
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xref: RHEA:17429
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.226
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[Term]
id: GO:0047031
@@ -291762,6 +300891,9 @@
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xref: RHEA:21008
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.229
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[Term]
id: GO:0047032
@@ -291775,6 +300907,9 @@
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xref: RHEA:20816
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
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@@ -291791,6 +300926,9 @@
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xref: RHEA:21420
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.231
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[Term]
id: GO:0047034
@@ -291803,6 +300941,8 @@
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xref: Reactome:R-HSA-2161789 "15S-HETE is oxidised to 15-oxoETE by 15-HEDH"
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
id: GO:0047035
@@ -291828,6 +300968,9 @@
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xref: Wikipedia:3alpha(17beta)-hydroxysteroid_dehydrogenase_(NAD+)
is_a: GO:0044594 ! 17-beta-hydroxysteroid dehydrogenase (NAD+) activity
+property_value: skos:broadMatch EC:1.1.1.51
+property_value: skos:exactMatch EC:1.1.1.239
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property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27695" xsd:anyURI
[Term]
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xref: RHEA:19209
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.247
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[Term]
id: GO:0047037
@@ -291853,6 +300999,9 @@
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xref: RHEA:10108
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
id: GO:0047038
@@ -291866,6 +301015,9 @@
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xref: RHEA:17389
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.250
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[Term]
id: GO:0047039
@@ -291878,6 +301030,9 @@
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xref: RHEA:21908
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.252
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[Term]
id: GO:0047040
@@ -291894,6 +301049,9 @@
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xref: RHEA:19509
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.33
+property_value: skos:exactMatch RHEA:19509
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[Term]
id: GO:0047041
@@ -291907,6 +301065,9 @@
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xref: RHEA:11556
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
id: GO:0047042
@@ -291933,6 +301094,9 @@
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xref: RHEA:19585
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
id: GO:0047044
@@ -291954,6 +301118,9 @@
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xref: RHEA:22400
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
id: GO:0047045
@@ -291968,11 +301135,14 @@
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xref: KEGG_REACTION:R01838
xref: MetaCyc:1.1.1.64-RXN
-xref: Reactome:R-HSA-193064 "HSD17B3-like proteins reducde ANDST to TEST"
xref: RHEA:14981
xref: Wikipedia:Testosterone_17beta-dehydrogenase_(NADP+)
is_a: GO:0072582 ! 17-beta-hydroxysteroid dehydrogenase (NADP+) activity
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[Term]
id: GO:0047046
@@ -291992,7 +301162,11 @@
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xref: RHEA:11900
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
id: GO:0047047
@@ -292003,6 +301177,8 @@
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xref: MetaCyc:1.1.1.92-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
id: GO:0047048
@@ -292018,6 +301194,9 @@
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xref: RHEA:22340
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
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@@ -292033,6 +301212,9 @@
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xref: RHEA:15949
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
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@@ -292049,6 +301231,9 @@
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xref: RHEA:11384
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[Term]
id: GO:0047051
@@ -292060,6 +301245,9 @@
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xref: RHEA:16465
is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor
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[Term]
id: GO:0047052
@@ -292073,7 +301261,10 @@
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xref: RHEA:13773
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.64
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property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
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xref: MetaCyc:1.14.21.2-RXN
xref: RHEA:20485
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.65
+property_value: skos:exactMatch RHEA:20485
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047054
@@ -292099,7 +301293,10 @@
xref: MetaCyc:1.1.3.34-RXN
xref: RHEA:23576
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.66
+property_value: skos:exactMatch RHEA:23576
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047055
@@ -292112,7 +301309,10 @@
xref: MetaCyc:1.1.3.35-RXN
xref: RHEA:17713
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.67
+property_value: skos:exactMatch RHEA:17713
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
@@ -292127,7 +301327,10 @@
xref: MetaCyc:1.1.3.36-RXN
xref: RHEA:21456
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.68
+property_value: skos:exactMatch RHEA:21456
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
@@ -292143,7 +301346,10 @@
xref: Reactome:R-HSA-6806647 "VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)"
xref: RHEA:57744
is_a: GO:0016728 ! oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor
+property_value: skos:exactMatch EC:1.17.4.4
+property_value: skos:exactMatch RHEA:57744
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047058
@@ -292155,7 +301361,10 @@
xref: MetaCyc:1.1.4.2-RXN
xref: RHEA:21560
is_a: GO:0016728 ! oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor
+property_value: skos:exactMatch EC:1.17.4.5
+property_value: skos:exactMatch RHEA:21560
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047059
@@ -292171,6 +301380,9 @@
xref: MetaCyc:RXN-11316
xref: RHEA:20157
is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.1.2.6
+property_value: skos:exactMatch RHEA:20157
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047060
@@ -292186,6 +301398,9 @@
xref: MetaCyc:1.1.99.27-RXN
xref: RHEA:21004
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.27
+property_value: skos:exactMatch RHEA:21004
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047061
@@ -292198,6 +301413,9 @@
xref: MetaCyc:1.1.99.28-RXN
xref: RHEA:20637
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.28
+property_value: skos:exactMatch RHEA:20637
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047062
@@ -292211,6 +301429,9 @@
xref: MetaCyc:1.10.1.1-RXN
xref: RHEA:22184
is_a: GO:0016680 ! oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.10.1.1
+property_value: skos:exactMatch RHEA:22184
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047063
@@ -292234,6 +301455,9 @@
xref: MetaCyc:1.10.3.7-RXN
xref: RHEA:24092
is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
+property_value: skos:exactMatch EC:1.21.3.4
+property_value: skos:exactMatch RHEA:24092
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047065
@@ -292247,6 +301471,9 @@
xref: MetaCyc:1.10.3.8-RXN
xref: RHEA:22616
is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
+property_value: skos:exactMatch EC:1.21.3.5
+property_value: skos:exactMatch RHEA:22616
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047066
@@ -292264,7 +301491,10 @@
xref: Reactome:R-HSA-9020273 "GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA"
xref: RHEA:19057
is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch EC:1.11.1.12
+property_value: skos:exactMatch RHEA:19057
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23399" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047067
@@ -292280,6 +301510,9 @@
xref: MetaCyc:1.12.5.1-RXN
xref: RHEA:18641
is_a: GO:0046994 ! oxidoreductase activity, acting on hydrogen as donor, with a quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.12.5.1
+property_value: skos:exactMatch RHEA:18641
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047068
@@ -292303,6 +301536,9 @@
xref: MetaCyc:H2-METHYLENE-THMPT-DEHYDRO-RXN
xref: RHEA:20017
is_a: GO:0046995 ! oxidoreductase activity, acting on hydrogen as donor, with other known acceptors
+property_value: skos:exactMatch EC:1.12.98.2
+property_value: skos:exactMatch RHEA:20017
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047069
@@ -292318,6 +301554,9 @@
xref: MetaCyc:1.13.11.10-RXN
xref: RHEA:23400
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.10
+property_value: skos:exactMatch RHEA:23400
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047070
@@ -292333,6 +301572,9 @@
xref: MetaCyc:1.13.11.16-RXN
xref: RHEA:23840
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.16
+property_value: skos:exactMatch RHEA:23840
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047071
@@ -292348,6 +301590,9 @@
xref: RHEA:21352
xref: UM-BBD_reactionID:r1151
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.25
+property_value: skos:exactMatch RHEA:21352
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047072
@@ -292361,6 +301606,9 @@
xref: MetaCyc:1.13.11.28-RXN
xref: RHEA:15369
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.28
+property_value: skos:exactMatch RHEA:15369
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047073
@@ -292375,6 +301623,9 @@
xref: RHEA:24416
xref: UM-BBD_reactionID:r1410
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.41
+property_value: skos:exactMatch RHEA:24416
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047074
@@ -292385,7 +301636,10 @@
xref: MetaCyc:RXN-10137
xref: RHEA:35595
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.37
+property_value: skos:exactMatch RHEA:35595
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25870" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047075
@@ -292400,6 +301654,9 @@
xref: RHEA:27522
xref: UM-BBD_reactionID:r1443
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.9
+property_value: skos:exactMatch RHEA:27522
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047077
@@ -292419,6 +301676,9 @@
xref: RHEA:10732
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
is_a: GO:0045289 ! luciferin monooxygenase activity
+property_value: skos:exactMatch EC:1.13.12.7
+property_value: skos:exactMatch RHEA:10732
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047078
@@ -292435,6 +301695,9 @@
xref: MetaCyc:1.13.11.47-RXN
xref: RHEA:17949
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.47
+property_value: skos:exactMatch RHEA:17949
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047079
@@ -292449,6 +301712,9 @@
xref: MetaCyc:1.14.11.10-RXN
xref: RHEA:23316
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.10
+property_value: skos:exactMatch RHEA:23316
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047080
@@ -292469,6 +301735,9 @@
xref: MetaCyc:1.14.11.3-RXN
xref: RHEA:21076
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.3
+property_value: skos:exactMatch RHEA:21076
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047081
@@ -292484,6 +301753,9 @@
xref: MetaCyc:1.14.12.4-RXN
xref: RHEA:10864
is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
+property_value: skos:exactMatch EC:1.14.13.242
+property_value: skos:exactMatch RHEA:10864
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047082
@@ -292498,6 +301770,9 @@
xref: MetaCyc:RXN-4505
xref: RHEA:15321
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.93
+property_value: skos:exactMatch RHEA:15321
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047083
@@ -292511,6 +301786,9 @@
xref: MetaCyc:1.14.13.36-RXN
xref: RHEA:16265
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.96
+property_value: skos:exactMatch RHEA:16265
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047084
@@ -292525,6 +301803,9 @@
xref: MetaCyc:1.14.13.37-RXN
xref: RHEA:23684
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.97
+property_value: skos:exactMatch RHEA:23684
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047085
@@ -292538,6 +301819,8 @@
xref: MetaCyc:1.14.13.42-RXN
xref: RHEA:50732
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:50732
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047086
@@ -292552,6 +301835,8 @@
xref: EC:1.14.13.54
xref: MetaCyc:1.14.13.54-RXN
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.54
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047087
@@ -292565,6 +301850,9 @@
xref: MetaCyc:1.14.13.55-RXN
xref: RHEA:22644
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.98
+property_value: skos:exactMatch RHEA:22644
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047088
@@ -292578,6 +301866,9 @@
xref: MetaCyc:1.14.13.56-RXN
xref: RHEA:10528
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.100
+property_value: skos:exactMatch RHEA:10528
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047089
@@ -292591,6 +301882,9 @@
xref: MetaCyc:1.14.13.57-RXN
xref: RHEA:10156
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.101
+property_value: skos:exactMatch RHEA:10156
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047090
@@ -292604,6 +301898,9 @@
xref: MetaCyc:1.14.13.58-RXN
xref: RHEA:23216
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.58
+property_value: skos:exactMatch RHEA:23216
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047091
@@ -292622,6 +301919,9 @@
xref: RHEA:23228
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.59
+property_value: skos:exactMatch RHEA:23228
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047092
@@ -292648,6 +301948,9 @@
xref: MetaCyc:1.14.13.62-RXN
xref: RHEA:19325
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.62
+property_value: skos:exactMatch RHEA:19325
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047094
@@ -292658,7 +301961,13 @@
synonym: "3-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (6-hydroxylating)" RELATED [EC:1.14.13.63]
xref: EC:1.14.13.63
xref: MetaCyc:1.14.13.63-RXN
+xref: RHEA:22204
+xref: RHEA:22208
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.63
+property_value: skos:narrowMatch RHEA:22204
+property_value: skos:narrowMatch RHEA:22208
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047095
@@ -292671,6 +301980,9 @@
xref: MetaCyc:1.14.13.66-RXN
xref: RHEA:33283
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.66
+property_value: skos:exactMatch RHEA:33283
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047096
@@ -292688,6 +302000,9 @@
xref: MetaCyc:1.14.99.12-RXN
xref: RHEA:22696
is_a: GO:0004508 ! steroid 17-alpha-monooxygenase activity
+property_value: skos:exactMatch EC:1.14.99.12
+property_value: skos:exactMatch RHEA:22696
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047097
@@ -292705,6 +302020,9 @@
xref: RHEA:16745
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.20
+property_value: skos:exactMatch RHEA:16745
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047098
@@ -292719,6 +302037,9 @@
xref: RHEA:12677
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
is_a: GO:0045289 ! luciferin monooxygenase activity
+property_value: skos:exactMatch EC:1.14.99.21
+property_value: skos:exactMatch RHEA:12677
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047099
@@ -292735,6 +302056,8 @@
xref: EC:1.17.1.1
xref: MetaCyc:1.17.1.1-RXN
is_a: GO:0016726 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.17.1.1
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047100
@@ -292754,6 +302077,9 @@
xref: MetaCyc:1.2.1.13-RXN
xref: RHEA:10296
is_a: GO:0043891 ! glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (phosphorylating) activity
+property_value: skos:exactMatch EC:1.2.1.13
+property_value: skos:exactMatch RHEA:10296
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047101
@@ -292787,6 +302113,9 @@
xref: RHEA:14469
xref: UM-BBD_reactionID:r1434
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.32
+property_value: skos:exactMatch RHEA:14469
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047103
@@ -292819,6 +302148,9 @@
xref: RHEA:19705
xref: UM-BBD_reactionID:r1374
is_a: GO:0050061 ! long-chain fatty aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.42
+property_value: skos:exactMatch RHEA:19705
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30270" xsd:anyURI
[Term]
@@ -292834,6 +302166,9 @@
xref: Reactome:R-HSA-71260 "ALDH9A1 tetramer dehydrogenates TEABL to form TEABT"
xref: RHEA:17985
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.47
+property_value: skos:exactMatch RHEA:17985
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047106
@@ -292846,6 +302181,9 @@
xref: MetaCyc:1.2.1.53-RXN
xref: RHEA:17273
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.53
+property_value: skos:exactMatch RHEA:17273
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047107
@@ -292861,6 +302199,9 @@
xref: MetaCyc:1.2.1.54-RXN
xref: RHEA:14381
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.54
+property_value: skos:exactMatch RHEA:14381
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047108
@@ -292875,6 +302216,9 @@
xref: MetaCyc:1.2.1.55-RXN
xref: RHEA:24352
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.279
+property_value: skos:exactMatch RHEA:24352
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047109
@@ -292890,6 +302234,9 @@
xref: MetaCyc:1.2.1.56-RXN
xref: RHEA:18269
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.280
+property_value: skos:exactMatch RHEA:18269
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047110
@@ -292902,6 +302249,9 @@
xref: MetaCyc:1.2.1.58-RXN
xref: RHEA:10372
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.58
+property_value: skos:exactMatch RHEA:10372
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047111
@@ -292914,6 +302264,9 @@
xref: MetaCyc:1.2.2.3-RXN
xref: RHEA:15189
is_a: GO:0016622 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.17.2.3
+property_value: skos:exactMatch RHEA:15189
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047112
@@ -292928,6 +302281,9 @@
xref: MetaCyc:1.2.3.3-RXN
xref: RHEA:20848
is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.2.3.3
+property_value: skos:exactMatch RHEA:20848
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047113
@@ -292941,6 +302297,9 @@
xref: MetaCyc:1.2.99.3-RXN
xref: RHEA:13881
is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors
+property_value: skos:exactMatch EC:1.2.5.2
+property_value: skos:exactMatch RHEA:13881
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047114
@@ -292955,6 +302314,9 @@
xref: MetaCyc:1.3.1.18-RXN
xref: RHEA:22248
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.18
+property_value: skos:exactMatch RHEA:22248
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047115
@@ -292967,6 +302329,9 @@
xref: MetaCyc:1.3.1.20-RXN
xref: RHEA:16729
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.20
+property_value: skos:exactMatch RHEA:16729
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047116
@@ -292986,6 +302351,9 @@
xref: MetaCyc:1.3.1.25-RXN
xref: RHEA:11560
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.25
+property_value: skos:exactMatch RHEA:11560
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047117
@@ -293016,6 +302384,9 @@
xref: MetaCyc:1.3.1.40-RXN
xref: RHEA:24268
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.40
+property_value: skos:exactMatch RHEA:24268
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047120
@@ -293034,6 +302405,9 @@
xref: RHEA:10744
xref: UM-BBD_reactionID:r0151
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.53
+property_value: skos:exactMatch RHEA:10744
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047121
@@ -293046,6 +302420,9 @@
xref: MetaCyc:1.3.99.16-RXN
xref: RHEA:11588
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.99.16
+property_value: skos:exactMatch RHEA:11588
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047122
@@ -293059,6 +302436,9 @@
xref: MetaCyc:1.3.99.18-RXN
xref: RHEA:16697
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.99.18
+property_value: skos:exactMatch RHEA:16697
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047123
@@ -293072,6 +302452,9 @@
xref: MetaCyc:1.3.99.19-RXN
xref: RHEA:14949
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.99.19
+property_value: skos:exactMatch RHEA:14949
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047124
@@ -293085,6 +302468,9 @@
xref: MetaCyc:1.4.1.11-RXN
xref: RHEA:19633
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.11
+property_value: skos:exactMatch RHEA:19633
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047125
@@ -293099,9 +302485,11 @@
synonym: "P2C reductase activity" RELATED [EC:1.5.1.21]
xref: EC:1.5.1.21
xref: MetaCyc:RXN-8166
-xref: Reactome:R-HSA-5693347 "CRYM reduces P2C to PPCA"
xref: RHEA:12524
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.21
+property_value: skos:exactMatch RHEA:12524
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047126
@@ -293115,6 +302503,9 @@
xref: MetaCyc:1.5.1.24-RXN
xref: RHEA:18661
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.24
+property_value: skos:exactMatch RHEA:18661
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047127
@@ -293126,7 +302517,10 @@
synonym: "thiomorpholine-3-carboxylate:NAD(P)+ 5,6-oxidoreductase activity" RELATED [EC:1.5.1.25]
xref: EC:1.5.1.25
xref: MetaCyc:1.5.1.25-RXN
+xref: Reactome:R-HSA-5693347 "CRYM reduces P2C to PPCA"
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.25
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047128
@@ -293140,6 +302534,9 @@
xref: MetaCyc:1.5.1.27-RXN
xref: RHEA:17569
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.27
+property_value: skos:exactMatch RHEA:17569
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047129
@@ -293153,6 +302550,9 @@
xref: MetaCyc:1.5.1.28-RXN
xref: RHEA:21592
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.28
+property_value: skos:exactMatch RHEA:21592
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047130
@@ -293171,6 +302571,9 @@
xref: Reactome:R-HSA-70938 "lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O"
xref: RHEA:19373
is_a: GO:0004753 ! saccharopine dehydrogenase activity
+property_value: skos:exactMatch EC:1.5.1.8
+property_value: skos:exactMatch RHEA:19373
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047131
@@ -293189,6 +302592,9 @@
xref: Reactome:R-HSA-70940 "saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+"
xref: RHEA:24520
is_a: GO:0004753 ! saccharopine dehydrogenase activity
+property_value: skos:exactMatch EC:1.5.1.9
+property_value: skos:exactMatch RHEA:24520
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047132
@@ -293200,6 +302606,9 @@
xref: MetaCyc:1.5.3.12-RXN
xref: RHEA:16621
is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.5.3.12
+property_value: skos:exactMatch RHEA:16621
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047133
@@ -293213,6 +302622,9 @@
xref: RHEA:10204
xref: UM-BBD_reactionID:r1380
is_a: GO:0046997 ! oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor
+property_value: skos:exactMatch EC:1.5.8.1
+property_value: skos:exactMatch RHEA:10204
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047134
@@ -293230,10 +302642,16 @@
synonym: "protein-disulphide reductase activity" BROAD []
xref: EC:1.8.1.8
xref: MetaCyc:1.6.4.4-RXN
+xref: RHEA:18749
+xref: RHEA:18753
is_a: GO:0015035 ! protein-disulfide reductase activity
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:exactMatch EC:1.8.1.8
+property_value: skos:narrowMatch RHEA:18749
+property_value: skos:narrowMatch RHEA:18753
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20219" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047135
@@ -293251,6 +302669,9 @@
xref: MetaCyc:1.6.4.9-RXN
xref: RHEA:11980
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:exactMatch EC:1.8.1.13
+property_value: skos:exactMatch RHEA:11980
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047136
@@ -293268,6 +302689,9 @@
xref: MetaCyc:1.6.6.12-RXN
xref: RHEA:19789
is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.7.1.11
+property_value: skos:exactMatch RHEA:19789
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047137
@@ -293280,7 +302704,11 @@
synonym: "NAD(P)H:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity" RELATED [EC:1.7.1.12]
xref: EC:1.7.1.12
xref: MetaCyc:1.7.1.12-RXN
+xref: RHEA:13109
+xref: RHEA:13113
is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
+property_value: skos:narrowMatch RHEA:13109
+property_value: skos:narrowMatch RHEA:13113
[Term]
id: GO:0047138
@@ -293310,6 +302738,9 @@
xref: MetaCyc:1.8.4.1-RXN
xref: RHEA:11464
is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
+property_value: skos:exactMatch EC:1.8.4.1
+property_value: skos:exactMatch RHEA:11464
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047140
@@ -293326,6 +302757,9 @@
xref: MetaCyc:1.8.4.3-RXN
xref: RHEA:13125
is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
+property_value: skos:exactMatch EC:1.8.4.3
+property_value: skos:exactMatch RHEA:13125
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047141
@@ -293339,6 +302773,9 @@
xref: MetaCyc:1.8.4.4-RXN
xref: RHEA:12613
is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
+property_value: skos:exactMatch EC:1.8.4.4
+property_value: skos:exactMatch RHEA:12613
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047142
@@ -293356,6 +302793,8 @@
xref: EC:1.8.4.7
xref: MetaCyc:1.8.4.7-RXN
is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
+property_value: skos:exactMatch EC:1.8.4.7
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047143
@@ -293370,6 +302809,9 @@
xref: RHEA:16349
xref: UM-BBD_reactionID:r0981
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.97.1.1
+property_value: skos:exactMatch RHEA:16349
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047144
@@ -293389,6 +302831,9 @@
xref: RHEA:14233
is_a: GO:0008374 ! O-acyltransferase activity
is_a: GO:0042171 ! lysophosphatidic acid acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.52
+property_value: skos:exactMatch RHEA:14233
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047145
@@ -293402,6 +302847,9 @@
xref: MetaCyc:2.1.1.109-RXN
xref: RHEA:11504
is_a: GO:0008171 ! O-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.109
+property_value: skos:exactMatch RHEA:11504
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047146
@@ -293417,6 +302865,9 @@
xref: MetaCyc:2.1.1.110-RXN
xref: RHEA:15561
is_a: GO:0008171 ! O-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.110
+property_value: skos:exactMatch RHEA:15561
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047147
@@ -293431,6 +302882,9 @@
xref: MetaCyc:2.1.1.19-RXN
xref: RHEA:13693
is_a: GO:0008170 ! N-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.19
+property_value: skos:exactMatch RHEA:13693
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047148
@@ -293445,6 +302899,9 @@
xref: MetaCyc:2.1.1.21-RXN
xref: RHEA:15837
is_a: GO:0008170 ! N-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.21
+property_value: skos:exactMatch RHEA:15837
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047149
@@ -293459,6 +302916,9 @@
xref: MetaCyc:2.1.1.3-RXN
xref: RHEA:22788
is_a: GO:0008172 ! S-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.3
+property_value: skos:exactMatch RHEA:22788
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047150
@@ -293474,7 +302934,10 @@
xref: Reactome:R-HSA-1614654 "BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY"
xref: RHEA:22336
is_a: GO:0008172 ! S-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.5
+property_value: skos:exactMatch RHEA:22336
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25592" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047151
@@ -293492,7 +302955,10 @@
xref: MetaCyc:2.1.1.74-RXN
xref: RHEA:16873
is_a: GO:0016300 ! tRNA (uridine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.74
+property_value: skos:exactMatch RHEA:16873
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26118" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047152
@@ -293514,6 +302980,9 @@
xref: MetaCyc:2.1.1.90-RXN
xref: RHEA:45204
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.90
+property_value: skos:exactMatch RHEA:45204
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047153
@@ -293532,6 +303001,9 @@
xref: MetaCyc:2.1.2.8-RXN
xref: RHEA:11280
is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity
+property_value: skos:exactMatch EC:2.1.2.8
+property_value: skos:exactMatch RHEA:11280
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047154
@@ -293552,6 +303024,9 @@
xref: RHEA:20764
xref: UM-BBD_reactionID:r0923
is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity
+property_value: skos:exactMatch EC:2.1.3.1
+property_value: skos:exactMatch RHEA:20764
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047155
@@ -293564,6 +303039,8 @@
xref: EC:2.1.3.7
xref: MetaCyc:2.1.3.7-RXN
is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity
+property_value: skos:exactMatch EC:2.1.3.7
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047156
@@ -293579,6 +303056,9 @@
xref: MetaCyc:2.2.1.4-RXN
xref: RHEA:21504
is_a: GO:0016744 ! transketolase or transaldolase activity
+property_value: skos:exactMatch EC:2.2.1.4
+property_value: skos:exactMatch RHEA:21504
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047157
@@ -293592,7 +303072,9 @@
xref: EC:2.3.1.100
xref: MetaCyc:2.3.1.100-RXN
is_a: GO:0016416 ! O-palmitoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.100
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21319" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047158
@@ -293607,6 +303089,9 @@
xref: MetaCyc:2.3.1.103-RXN
xref: RHEA:22664
is_a: GO:0016753 ! O-sinapoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.103
+property_value: skos:exactMatch RHEA:22664
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047159
@@ -293619,7 +303104,10 @@
xref: MetaCyc:PLASMALOGEN-SYNTHASE-RXN
xref: RHEA:10344
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.25
+property_value: skos:exactMatch RHEA:10344
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047160
@@ -293633,6 +303121,9 @@
xref: MetaCyc:2.3.1.105-RXN
xref: RHEA:18557
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.105
+property_value: skos:exactMatch RHEA:18557
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047161
@@ -293647,6 +303138,9 @@
xref: MetaCyc:2.3.1.106-RXN
xref: RHEA:10952
is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.106
+property_value: skos:exactMatch RHEA:10952
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047162
@@ -293668,6 +303162,9 @@
xref: MetaCyc:2.3.1.107-RXN
xref: RHEA:24496
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.107
+property_value: skos:exactMatch RHEA:24496
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047163
@@ -293680,6 +303177,9 @@
xref: MetaCyc:2.3.1.114-RXN
xref: RHEA:21060
is_a: GO:0050735 ! N-malonyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.114
+property_value: skos:exactMatch RHEA:21060
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047164
@@ -293697,6 +303197,9 @@
xref: MetaCyc:RXN-4703
xref: RHEA:15581
is_a: GO:0050736 ! O-malonyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.115
+property_value: skos:exactMatch RHEA:15581
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047165
@@ -293711,6 +303214,9 @@
xref: MetaCyc:2.3.1.116-RXN
xref: RHEA:20085
is_a: GO:0050736 ! O-malonyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.116
+property_value: skos:exactMatch RHEA:20085
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047166
@@ -293722,6 +303228,9 @@
xref: MetaCyc:2.3.1.121-RXN
xref: RHEA:16245
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.121
+property_value: skos:exactMatch RHEA:16245
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047167
@@ -293734,6 +303243,9 @@
xref: MetaCyc:2.3.1.125-RXN
xref: RHEA:21996
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.125
+property_value: skos:exactMatch RHEA:21996
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047168
@@ -293746,6 +303258,9 @@
xref: MetaCyc:2.3.1.126-RXN
xref: RHEA:20756
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.126
+property_value: skos:exactMatch RHEA:20756
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047169
@@ -293759,6 +303274,9 @@
xref: MetaCyc:2.3.1.130-RXN
xref: RHEA:12997
is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.130
+property_value: skos:exactMatch RHEA:12997
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047170
@@ -293771,6 +303289,9 @@
xref: MetaCyc:2.3.1.131-RXN
xref: RHEA:23308
is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.131
+property_value: skos:exactMatch RHEA:23308
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047171
@@ -293782,6 +303303,9 @@
xref: MetaCyc:2.3.1.132-RXN
xref: RHEA:14261
is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.132
+property_value: skos:exactMatch RHEA:14261
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047172
@@ -293794,6 +303318,9 @@
xref: MetaCyc:2.3.1.133-RXN
xref: RHEA:12124
is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.133
+property_value: skos:exactMatch RHEA:12124
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047173
@@ -293808,7 +303335,10 @@
xref: Reactome:R-HSA-975608 "LRAT esterifies RBP2:atROL and FACYLs to atREs"
xref: RHEA:17469
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.135
+property_value: skos:exactMatch RHEA:17469
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047174
@@ -293827,6 +303357,9 @@
xref: RHEA:12436
is_a: GO:0016410 ! N-acyltransferase activity
is_a: GO:0050734 ! hydroxycinnamoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.138
+property_value: skos:exactMatch RHEA:12436
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047175
@@ -293840,6 +303373,9 @@
xref: MetaCyc:2.3.1.141-RXN
xref: RHEA:17057
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.141
+property_value: skos:exactMatch RHEA:17057
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047176
@@ -293855,6 +303391,9 @@
xref: MetaCyc:2.3.1.143-RXN
xref: RHEA:19109
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.143
+property_value: skos:exactMatch RHEA:19109
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047177
@@ -293867,6 +303406,9 @@
xref: MetaCyc:2.3.1.147-RXN
xref: RHEA:15409
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.147
+property_value: skos:exactMatch RHEA:15409
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047178
@@ -293878,6 +303420,9 @@
xref: MetaCyc:2.3.1.148-RXN
xref: RHEA:20972
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.148
+property_value: skos:exactMatch RHEA:20972
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047179
@@ -293890,6 +303435,9 @@
xref: MetaCyc:2.3.1.149-RXN
xref: RHEA:11048
is_a: GO:0016407 ! acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.149
+property_value: skos:exactMatch RHEA:11048
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047180
@@ -293902,6 +303450,9 @@
xref: MetaCyc:2.3.1.150-RXN
xref: RHEA:22856
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.150
+property_value: skos:exactMatch RHEA:22856
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047181
@@ -293913,6 +303464,9 @@
xref: MetaCyc:2.3.1.151-RXN
xref: RHEA:19305
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.151
+property_value: skos:exactMatch RHEA:19305
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047182
@@ -293924,6 +303478,9 @@
xref: MetaCyc:2.3.1.152-RXN
xref: RHEA:23524
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.152
+property_value: skos:exactMatch RHEA:23524
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047183
@@ -293936,6 +303493,9 @@
xref: MetaCyc:RXN-7945
xref: RHEA:15661
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.153
+property_value: skos:exactMatch RHEA:15661
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047184
@@ -293955,6 +303515,9 @@
xref: Reactome:R-HSA-1482794 "CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible)"
xref: RHEA:12937
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.23
+property_value: skos:exactMatch RHEA:12937
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047185
@@ -293968,6 +303531,9 @@
xref: MetaCyc:2.3.1.44-RXN
xref: RHEA:18305
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.44
+property_value: skos:exactMatch RHEA:18305
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047186
@@ -293989,6 +303555,8 @@
xref: MetaCyc:RXN-7864
xref: RHEA:81827
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.45
+property_value: skos:exactMatch RHEA:81827
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29625" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30557" xsd:anyURI
@@ -294006,6 +303574,9 @@
xref: RHEA:20393
is_a: GO:0016418 ! S-acetyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.3.1.49
+property_value: skos:exactMatch RHEA:20393
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047188
@@ -294023,6 +303594,9 @@
xref: MetaCyc:2.3.1.56-RXN
xref: RHEA:20325
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.56
+property_value: skos:exactMatch RHEA:20325
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047189
@@ -294040,6 +303614,9 @@
xref: MetaCyc:2.3.1.58-RXN
xref: RHEA:13465
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.58
+property_value: skos:exactMatch RHEA:13465
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047190
@@ -294054,6 +303631,9 @@
xref: MetaCyc:2.3.1.62-RXN
xref: RHEA:10332
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.62
+property_value: skos:exactMatch RHEA:10332
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047191
@@ -294065,6 +303645,9 @@
xref: MetaCyc:2.3.1.63-RXN
xref: RHEA:23992
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.63
+property_value: skos:exactMatch RHEA:23992
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047192
@@ -294088,6 +303671,9 @@
xref: MetaCyc:2.3.1.67-RXN
xref: RHEA:18461
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.67
+property_value: skos:exactMatch RHEA:18461
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047193
@@ -294115,6 +303701,9 @@
xref: MetaCyc:2.3.1.72-RXN
xref: RHEA:21180
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.72
+property_value: skos:exactMatch RHEA:21180
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047195
@@ -294127,6 +303716,9 @@
xref: MetaCyc:2.3.1.73-RXN
xref: RHEA:13301
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.73
+property_value: skos:exactMatch RHEA:13301
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047196
@@ -294140,10 +303732,15 @@
synonym: "wax-ester synthase activity" RELATED [EC:2.3.1.75]
xref: EC:2.3.1.75
xref: MetaCyc:2.3.1.75-RXN
+xref: MetaCyc:RXNQT-4193
xref: Reactome:R-HSA-5696424 "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters"
xref: Reactome:R-HSA-8848582 "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester"
xref: RHEA:38443
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.75
+property_value: skos:exactMatch MetaCyc:2.3.1.75-RXN
+property_value: skos:exactMatch RHEA:38443
+property_value: skos:narrowMatch MetaCyc:RXNQT-4193
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -294158,6 +303755,9 @@
xref: MetaCyc:2.3.1.77-RXN
xref: RHEA:16897
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.77
+property_value: skos:exactMatch RHEA:16897
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047198
@@ -294172,6 +303772,9 @@
xref: Reactome:R-HSA-5433066 "Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C"
xref: RHEA:19213
is_a: GO:0140085 ! L-amino-acid N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.80
+property_value: skos:exactMatch RHEA:19213
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047199
@@ -294184,6 +303787,9 @@
xref: MetaCyc:2.3.1.83-RXN
xref: RHEA:19285
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.83
+property_value: skos:exactMatch RHEA:19285
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047200
@@ -294200,6 +303806,9 @@
xref: MetaCyc:2.3.1.89-RXN
xref: RHEA:13085
is_a: GO:0008080 ! N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.89
+property_value: skos:exactMatch RHEA:13085
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047201
@@ -294212,6 +303821,9 @@
xref: MetaCyc:2.3.1.90-RXN
xref: RHEA:11416
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.90
+property_value: skos:exactMatch RHEA:11416
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047202
@@ -294225,6 +303837,9 @@
xref: MetaCyc:2.3.1.91-RXN
xref: RHEA:12024
is_a: GO:0016753 ! O-sinapoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.91
+property_value: skos:exactMatch RHEA:12024
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047203
@@ -294239,6 +303854,9 @@
xref: MetaCyc:RXN-8694
xref: RHEA:12360
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.93
+property_value: skos:exactMatch RHEA:12360
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047204
@@ -294253,6 +303871,9 @@
xref: MetaCyc:2.3.1.98-RXN
xref: RHEA:23204
is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.98
+property_value: skos:exactMatch RHEA:23204
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047205
@@ -294265,6 +303886,9 @@
xref: MetaCyc:2.3.1.99-RXN
xref: RHEA:15021
is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.99
+property_value: skos:exactMatch RHEA:15021
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047206
@@ -294280,7 +303904,10 @@
xref: MetaCyc:2.3.2.10-RXN
xref: RHEA:12432
is_a: GO:0016755 ! aminoacyltransferase activity
+property_value: skos:exactMatch EC:2.3.2.10
+property_value: skos:exactMatch RHEA:12432
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047207
@@ -294299,6 +303926,8 @@
xref: EC:2.4.1.100
xref: MetaCyc:2.4.1.100-RXN
is_a: GO:0050738 ! fructosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.100
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047208
@@ -294314,6 +303943,9 @@
xref: MetaCyc:2.4.1.104-RXN
xref: RHEA:14325
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.104
+property_value: skos:exactMatch RHEA:14325
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047209
@@ -294328,6 +303960,9 @@
xref: MetaCyc:2.4.1.111-RXN
xref: RHEA:23944
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.111
+property_value: skos:exactMatch RHEA:23944
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047211
@@ -294343,6 +303978,8 @@
xref: MetaCyc:2.4.1.113-RXN
is_a: GO:0016758 ! hexosyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.4.1.113
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047212
@@ -294358,6 +303995,9 @@
xref: MetaCyc:2.4.1.114-RXN
xref: RHEA:10236
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.114
+property_value: skos:exactMatch RHEA:10236
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047213
@@ -294374,6 +304014,9 @@
xref: MetaCyc:2.4.1.115-RXN
xref: RHEA:20093
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.115
+property_value: skos:exactMatch RHEA:20093
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047214
@@ -294388,6 +304031,9 @@
xref: MetaCyc:2.4.1.116-RXN
xref: RHEA:12144
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.116
+property_value: skos:exactMatch RHEA:12144
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047215
@@ -294411,6 +304057,9 @@
xref: MetaCyc:2.4.1.121-RXN
xref: RHEA:14921
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.121
+property_value: skos:exactMatch RHEA:14921
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047216
@@ -294428,6 +304077,9 @@
xref: MetaCyc:2.4.1.123-RXN
xref: RHEA:12464
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.123
+property_value: skos:exactMatch RHEA:12464
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047217
@@ -294454,6 +304106,9 @@
xref: MetaCyc:2.4.1.126-RXN
xref: RHEA:21636
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.126
+property_value: skos:exactMatch RHEA:21636
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047219
@@ -294469,6 +304124,9 @@
xref: MetaCyc:2.4.1.127-RXN
xref: RHEA:11520
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.127
+property_value: skos:exactMatch RHEA:11520
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047220
@@ -294486,6 +304144,9 @@
xref: RHEA:11780
is_a: GO:0035250 ! UDP-galactosyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.134
+property_value: skos:exactMatch RHEA:11780
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047221
@@ -294505,6 +304166,9 @@
xref: MetaCyc:2.4.1.137-RXN
xref: RHEA:14285
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.137
+property_value: skos:exactMatch RHEA:14285
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047222
@@ -294518,6 +304182,9 @@
xref: MetaCyc:2.4.1.138-RXN
xref: RHEA:13705
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.138
+property_value: skos:exactMatch RHEA:13705
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047223
@@ -294531,9 +304198,12 @@
synonym: "uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase (elongating)" RELATED [EC:2.4.1.146]
xref: EC:2.4.1.146
xref: MetaCyc:2.4.1.146-RXN
+xref: Reactome:R-HSA-5617037 "POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1"
xref: Reactome:R-HSA-5617096 "Defective POMGNT1 does not transfer GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1"
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.146
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047224
@@ -294548,10 +304218,15 @@
synonym: "uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase activity" RELATED [EC:2.4.1.147]
xref: EC:2.4.1.147
xref: MetaCyc:2.4.1.147-RXN
-xref: Reactome:R-HSA-914010 "B3GNT6 transfers GlcNAc to Tn antigen"
+xref: RHEA:46880
+xref: RHEA:46884
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.147
+property_value: skos:narrowMatch RHEA:46880
+property_value: skos:narrowMatch RHEA:46884
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27859" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047225
@@ -294566,8 +304241,13 @@
synonym: "uridine diphosphoacetylglucosamine-mucin beta(1->6)-acetylglucosaminyltransferase B" RELATED [EC:2.4.1.148]
xref: EC:2.4.1.148
xref: MetaCyc:2.4.1.148-RXN
+xref: RHEA:56188
+xref: RHEA:56192
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.148
+property_value: skos:narrowMatch RHEA:56188
+property_value: skos:narrowMatch RHEA:56192
[Term]
id: GO:0047227
@@ -294583,6 +304263,9 @@
xref: MetaCyc:2.4.1.156-RXN
xref: RHEA:21148
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.156
+property_value: skos:exactMatch RHEA:21148
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047228
@@ -294599,7 +304282,10 @@
xref: MetaCyc:2.4.1.157-RXN
xref: RHEA:47612
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.337
+property_value: skos:exactMatch RHEA:47612
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047229
@@ -294616,6 +304302,9 @@
xref: MetaCyc:HYDROXYDOCOSANOATE-TRANS-RXN
xref: RHEA:22316
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.158
+property_value: skos:exactMatch RHEA:22316
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047230
@@ -294630,6 +304319,9 @@
xref: RHEA:22528
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.159
+property_value: skos:exactMatch RHEA:22528
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047231
@@ -294646,6 +304338,9 @@
xref: MetaCyc:2.4.1.160-RXN
xref: RHEA:20177
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.160
+property_value: skos:exactMatch RHEA:20177
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047232
@@ -294671,7 +304366,10 @@
xref: MetaCyc:2.4.1.165-RXN
xref: RHEA:81947
is_a: GO:0008376 ! acetylgalactosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.165
+property_value: skos:exactMatch RHEA:81947
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18752" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047234
@@ -294687,6 +304385,9 @@
xref: MetaCyc:RXN-11490
xref: RHEA:14125
is_a: GO:0008378 ! galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.166
+property_value: skos:exactMatch RHEA:14125
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047235
@@ -294703,6 +304404,9 @@
xref: MetaCyc:2.4.1.167-RXN
xref: RHEA:10088
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.167
+property_value: skos:exactMatch RHEA:10088
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047236
@@ -294718,6 +304422,9 @@
xref: MetaCyc:2.4.1.171-RXN
xref: RHEA:20205
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.171
+property_value: skos:exactMatch RHEA:20205
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047237
@@ -294733,6 +304440,9 @@
xref: MetaCyc:2.4.1.174-RXN
xref: RHEA:23464
is_a: GO:0008376 ! acetylgalactosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.174
+property_value: skos:exactMatch RHEA:23464
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047238
@@ -294748,11 +304458,13 @@
synonym: "uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II activity" RELATED [EC:2.4.1.175]
xref: EC:2.4.1.175
xref: MetaCyc:RXN-16325
-xref: Reactome:R-HSA-1971482 "CSGALNACTs transfer GalNAc to CS linker glycan"
-xref: Reactome:R-HSA-1971487 "Chondroitin polymerase complex transfers GalNAc to CS chain"
+xref: Reactome:R-HSA-1971482 "The addition of GalNAc to the terminal glucuronate residue forms chondroitin"
+xref: Reactome:R-HSA-1971487 "CHPF,CHSY3 transfer GalNAc to chondroitin"
xref: Reactome:R-HSA-3595176 "Defective CHSY1 does not transfer GalNAc to chondroitin"
-xref: Reactome:R-HSA-9632033 "CSGALNACTs transfer GalNAc to CS chain"
+xref: Reactome:R-HSA-9632033 "CHSY1 transfers GalNAc to chondroitin"
is_a: GO:0008376 ! acetylgalactosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.175
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047239
@@ -294767,6 +304479,9 @@
xref: MetaCyc:2.4.1.178-RXN
xref: RHEA:15961
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.178
+property_value: skos:exactMatch RHEA:15961
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047240
@@ -294782,6 +304497,9 @@
xref: RHEA:18413
is_a: GO:0035250 ! UDP-galactosyltransferase activity
is_a: GO:0048531 ! beta-1,3-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.179
+property_value: skos:exactMatch RHEA:18413
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047241
@@ -294797,6 +304515,9 @@
xref: RHEA:28366
is_a: GO:0000026 ! alpha-1,2-mannosyltransferase activity
is_a: GO:0008194 ! UDP-glycosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.180
+property_value: skos:exactMatch RHEA:28366
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047242
@@ -294810,6 +304531,8 @@
xref: EC:2.4.1.181
xref: MetaCyc:2.4.1.181-RXN
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.181
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047243
@@ -294824,6 +304547,8 @@
xref: EC:2.4.1.185
xref: MetaCyc:2.4.1.185-RXN
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.185
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047244
@@ -294839,6 +304564,9 @@
xref: RHEA:16053
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.187
+property_value: skos:exactMatch RHEA:16053
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047245
@@ -294853,6 +304581,9 @@
xref: MetaCyc:2.4.1.188-RXN
xref: RHEA:20952
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.188
+property_value: skos:exactMatch RHEA:20952
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047246
@@ -294869,6 +304600,9 @@
xref: MetaCyc:2.4.1.190-RXN
xref: RHEA:14149
is_a: GO:0015020 ! glucuronosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.190
+property_value: skos:exactMatch RHEA:14149
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047247
@@ -294886,6 +304620,9 @@
xref: MetaCyc:2.4.1.191-RXN
xref: RHEA:22116
is_a: GO:0015020 ! glucuronosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.191
+property_value: skos:exactMatch RHEA:22116
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047248
@@ -294901,6 +304638,9 @@
xref: MetaCyc:2.4.1.192-RXN
xref: RHEA:19329
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.192
+property_value: skos:exactMatch RHEA:19329
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047249
@@ -294916,6 +304656,9 @@
xref: MetaCyc:2.4.1.193-RXN
xref: RHEA:14461
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.193
+property_value: skos:exactMatch RHEA:14461
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047250
@@ -294935,6 +304678,9 @@
xref: MetaCyc:2.4.1.194-RXN
xref: RHEA:15153
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.194
+property_value: skos:exactMatch RHEA:15153
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047251
@@ -294953,6 +304699,9 @@
xref: MetaCyc:2.4.1.195-RXN
xref: RHEA:13757
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.195
+property_value: skos:exactMatch RHEA:13757
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047252
@@ -294964,6 +304713,8 @@
xref: EC:2.4.1.199
xref: MetaCyc:2.4.1.199-RXN
is_a: GO:0000030 ! mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.199
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047253
@@ -294983,6 +304734,9 @@
xref: RHEA:19945
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.4.1.201
+property_value: skos:exactMatch RHEA:19945
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047254
@@ -294996,6 +304750,9 @@
xref: MetaCyc:RXN-7022
xref: RHEA:15541
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.202
+property_value: skos:exactMatch RHEA:15541
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047255
@@ -295011,6 +304768,8 @@
xref: EC:2.4.1.205
xref: MetaCyc:2.4.1.205-RXN
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.205
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047256
@@ -295027,6 +304786,9 @@
xref: Reactome:R-HSA-9846501 "B3GNT5 transfers GlcNAc to LacCer"
xref: RHEA:13905
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.206
+property_value: skos:exactMatch RHEA:13905
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047257
@@ -295043,6 +304805,9 @@
xref: RHEA:19165
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.208
+property_value: skos:exactMatch RHEA:19165
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047258
@@ -295061,6 +304826,9 @@
xref: MetaCyc:2.4.1.23-RXN
xref: RHEA:19485
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.23
+property_value: skos:exactMatch RHEA:19485
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047259
@@ -295074,6 +304842,8 @@
xref: EC:2.4.1.32
xref: MetaCyc:2.4.1.32-RXN
is_a: GO:0019187 ! beta-1,4-mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.32
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047260
@@ -295090,6 +304860,9 @@
xref: MetaCyc:2.4.1.36-RXN
xref: RHEA:14605
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.36
+property_value: skos:exactMatch RHEA:14605
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047261
@@ -295105,6 +304878,9 @@
xref: MetaCyc:2.4.1.39-RXN
xref: RHEA:14153
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.39
+property_value: skos:exactMatch RHEA:14153
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047262
@@ -295120,6 +304896,9 @@
xref: RHEA:13573
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.43
+property_value: skos:exactMatch RHEA:13573
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047263
@@ -295142,7 +304921,16 @@
synonym: "guanosine diphosphomannose-heteroglycan alpha-mannosyltransferase activity" RELATED [EC:2.4.1.48]
synonym: "heteropolysaccharide alpha-mannosyltransferase activity" EXACT []
xref: EC:2.4.1.48
+xref: KEGG_REACTION:R03768
+xref: KEGG_REACTION:R03769
+xref: MetaCyc:2.4.1.48-RXN
+xref: MetaCyc:RXN-7992
is_a: GO:0000030 ! mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.48
+property_value: skos:narrowMatch KEGG_REACTION:R03768
+property_value: skos:narrowMatch KEGG_REACTION:R03769
+property_value: skos:narrowMatch MetaCyc:2.4.1.48-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-7992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -295158,6 +304946,9 @@
xref: MetaCyc:TEICHOICSYN5-RXN
xref: RHEA:15845
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.52
+property_value: skos:exactMatch RHEA:15845
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047266
@@ -295174,6 +304965,9 @@
xref: MetaCyc:RXN-18017
xref: RHEA:10068
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.53
+property_value: skos:exactMatch RHEA:10068
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047267
@@ -295186,6 +304980,8 @@
synonym: "guanosine diphosphomannose-undecaprenyl phosphate mannosyltransferase activity" RELATED [EC:2.4.1.54]
xref: EC:2.4.1.54
is_a: GO:0000030 ! mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.54
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047268
@@ -295198,6 +304994,9 @@
xref: MetaCyc:2.4.1.67-RXN
xref: RHEA:20776
is_a: GO:0008378 ! galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.67
+property_value: skos:exactMatch RHEA:20776
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047269
@@ -295211,6 +305010,9 @@
xref: MetaCyc:2.4.1.53-RXN
xref: RHEA:21012
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.70
+property_value: skos:exactMatch RHEA:21012
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047270
@@ -295226,6 +305028,9 @@
xref: RHEA:30003
is_a: GO:0035251 ! UDP-glucosyltransferase activity
relationship: part_of GO:0009103 ! lipopolysaccharide biosynthetic process
+property_value: skos:exactMatch EC:2.4.1.73
+property_value: skos:exactMatch MetaCyc:RXN0-5125
+property_value: skos:exactMatch RHEA:30003
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -295239,6 +305044,8 @@
xref: EC:2.4.1.74
xref: MetaCyc:2.4.1.74-RXN
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.74
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047272
@@ -295252,6 +305059,8 @@
xref: EC:2.4.1.78
xref: MetaCyc:2.4.1.78-RXN
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.78
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047273
@@ -295276,6 +305085,9 @@
xref: Reactome:R-HSA-8878914 "B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer"
xref: RHEA:22252
is_a: GO:0008376 ! acetylgalactosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.79
+property_value: skos:exactMatch RHEA:22252
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047274
@@ -295291,6 +305103,9 @@
xref: MetaCyc:2.4.1.82-RXN
xref: RHEA:20161
is_a: GO:0008378 ! galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.82
+property_value: skos:exactMatch RHEA:20161
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047275
@@ -295332,6 +305147,9 @@
xref: MetaCyc:2.4.1.151-RXN
xref: RHEA:13013
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.87
+property_value: skos:exactMatch RHEA:13013
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047277
@@ -295346,6 +305164,9 @@
xref: MetaCyc:2.4.1.88-RXN
xref: RHEA:22164
is_a: GO:0008376 ! acetylgalactosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.88
+property_value: skos:exactMatch RHEA:22164
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047278
@@ -295358,6 +305179,8 @@
xref: KEGG_REACTION:R00062
xref: RHEA:16885
is_a: GO:0015020 ! glucuronosyltransferase activity
+property_value: skos:exactMatch RHEA:16885
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047279
@@ -295376,6 +305199,9 @@
xref: MetaCyc:2.4.1.96-RXN
xref: RHEA:20341
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.96
+property_value: skos:exactMatch RHEA:20341
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047280
@@ -295394,6 +305220,9 @@
xref: Reactome:R-HSA-197250 "NAMPT transfers PRIB to NAM to form NAMN"
xref: RHEA:16149
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.12
+property_value: skos:exactMatch RHEA:16149
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047281
@@ -295409,6 +305238,9 @@
xref: MetaCyc:2.4.2.20-RXN
xref: RHEA:10232
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.20
+property_value: skos:exactMatch RHEA:10232
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047282
@@ -295423,6 +305255,9 @@
xref: MetaCyc:2.4.2.27-RXN
xref: RHEA:24392
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.27
+property_value: skos:exactMatch RHEA:24392
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047283
@@ -295434,6 +305269,9 @@
xref: MetaCyc:2.4.2.32-RXN
xref: RHEA:15361
is_a: GO:0035252 ! UDP-xylosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.32
+property_value: skos:exactMatch RHEA:15361
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047284
@@ -295445,6 +305283,9 @@
xref: MetaCyc:2.4.2.33-RXN
xref: RHEA:18361
is_a: GO:0042285 ! xylosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.33
+property_value: skos:exactMatch RHEA:18361
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047285
@@ -295456,6 +305297,9 @@
xref: MetaCyc:2.4.2.35-RXN
xref: RHEA:19701
is_a: GO:0035252 ! UDP-xylosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.35
+property_value: skos:exactMatch RHEA:19701
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047286
@@ -295471,6 +305315,9 @@
xref: Reactome:R-HSA-5336421 "DT fragment A ADP-ribosylates target cell EEF"
xref: RHEA:11820
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.36
+property_value: skos:exactMatch RHEA:11820
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047287
@@ -295484,15 +305331,17 @@
[Term]
id: GO:0047288
-name: beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase
+name: beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase activity
namespace: molecular_function
-def: "Catalysis of the reaction: beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H+." [EC:2.4.3.2, MetaCyc:2.4.99.2-RXN]
+def: "Catalysis of the reaction: beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H+." [RHEA:52380]
synonym: "monosialoganglioside sialyltransferase" EXACT [EC:2.4.3.2]
xref: EC:2.4.3.2
-xref: MetaCyc:2.4.99.2-RXN
-xref: Reactome:R-HSA-981497 "ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position"
-xref: RHEA:18021
+xref: MetaCyc:RXN-18256
+xref: RHEA:52380
is_a: GO:0008373 ! sialyltransferase activity
+property_value: skos:exactMatch EC:2.4.3.2
+property_value: skos:exactMatch RHEA:52380
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047289
@@ -295504,6 +305353,9 @@
xref: MetaCyc:2.4.99.5-RXN
xref: RHEA:11664
is_a: GO:0008373 ! sialyltransferase activity
+property_value: skos:exactMatch EC:2.4.3.5
+property_value: skos:exactMatch RHEA:11664
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047290
@@ -295522,6 +305374,9 @@
xref: Reactome:R-HSA-981809 "ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen"
xref: RHEA:53896
is_a: GO:0008373 ! sialyltransferase activity
+property_value: skos:exactMatch EC:2.4.3.7
+property_value: skos:exactMatch RHEA:53896
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047291
@@ -295537,6 +305392,9 @@
xref: MetaCyc:2.4.99.9-RXN
xref: RHEA:18417
is_a: GO:0008373 ! sialyltransferase activity
+property_value: skos:exactMatch EC:2.4.3.9
+property_value: skos:exactMatch RHEA:18417
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047292
@@ -295548,7 +305406,16 @@
synonym: "dimethylallylpyrophosphate:3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity" RELATED [EC:2.5.1.36]
synonym: "dimethylallylpyrophosphate:trihydroxypterocarpan dimethylallyl transferase activity" RELATED [EC:2.5.1.36]
xref: EC:2.5.1.36
+xref: MetaCyc:RXN-4509
+xref: MetaCyc:RXN-4510
+xref: RHEA:19345
+xref: RHEA:23184
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.36
+property_value: skos:narrowMatch MetaCyc:RXN-4509
+property_value: skos:narrowMatch MetaCyc:RXN-4510
+property_value: skos:narrowMatch RHEA:19345
+property_value: skos:narrowMatch RHEA:23184
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -295578,6 +305445,8 @@
xref: MetaCyc:2.5.1.41-RXN
xref: RHEA:23404
is_a: GO:0004659 ! prenyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.41
+property_value: skos:exactMatch RHEA:23404
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26832" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
@@ -295597,6 +305466,8 @@
xref: MetaCyc:2.5.1.42-RXN
xref: RHEA:18109
is_a: GO:0004659 ! prenyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.42
+property_value: skos:exactMatch RHEA:18109
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26832" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29428" xsd:anyURI
@@ -295605,12 +305476,15 @@
id: GO:0047296
name: homospermidine synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 2 putrescine = NH3 + sym-homospermidine." [EC:2.5.1.44, MetaCyc:2.5.1.44-RXN]
+def: "Catalysis of the reaction: 2 putrescine = NH3 + sym-homospermidine." [EC:2.5.1.44]
synonym: "putrescine:putrescine 4-aminobutyltransferase (ammonia-forming)" RELATED [EC:2.5.1.44]
xref: EC:2.5.1.44
xref: MetaCyc:2.5.1.44-RXN
xref: RHEA:18645
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.44
+property_value: skos:exactMatch RHEA:18645
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047297
@@ -295625,6 +305499,8 @@
xref: MetaCyc:2.6.1.14-RXN
xref: RHEA:19813
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.14
+property_value: skos:exactMatch RHEA:19813
[Term]
id: GO:0047298
@@ -295644,6 +305520,9 @@
xref: MetaCyc:2.6.1.22-RXN
xref: RHEA:13993
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.22
+property_value: skos:exactMatch RHEA:13993
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047299
@@ -295659,6 +305538,9 @@
xref: MetaCyc:2.6.1.28-RXN
xref: RHEA:13741
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.28
+property_value: skos:exactMatch RHEA:13741
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047300
@@ -295675,6 +305557,9 @@
xref: MetaCyc:2.6.1.30-RXN
xref: RHEA:12841
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.30
+property_value: skos:exactMatch RHEA:12841
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047301
@@ -295692,6 +305577,9 @@
xref: MetaCyc:2.6.1.32-RXN
xref: RHEA:11468
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.32
+property_value: skos:exactMatch RHEA:11468
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047302
@@ -295707,6 +305595,9 @@
xref: MetaCyc:RXN-12812
xref: RHEA:31663
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.34
+property_value: skos:exactMatch RHEA:31663
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047303
@@ -295722,6 +305613,9 @@
xref: MetaCyc:2.6.1.35-RXN
xref: RHEA:17141
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.35
+property_value: skos:exactMatch RHEA:17141
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047304
@@ -295741,6 +305635,9 @@
xref: MetaCyc:2.6.1.37-RXN
xref: RHEA:17021
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.37
+property_value: skos:exactMatch RHEA:17021
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047305
@@ -295768,6 +305665,9 @@
xref: Reactome:R-HSA-909780 "(R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine"
xref: RHEA:18393
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.40
+property_value: skos:exactMatch RHEA:18393
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047306
@@ -295784,6 +305684,9 @@
xref: MetaCyc:2.6.1.41-RXN
xref: RHEA:23836
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.41
+property_value: skos:exactMatch RHEA:23836
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047307
@@ -295799,6 +305702,9 @@
xref: MetaCyc:2.6.1.46-RXN
xref: RHEA:12380
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.46
+property_value: skos:exactMatch RHEA:12380
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047308
@@ -295815,6 +305721,9 @@
xref: MetaCyc:2.6.1.47-RXN
xref: RHEA:18809
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.47
+property_value: skos:exactMatch RHEA:18809
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047309
@@ -295834,6 +305743,9 @@
xref: MetaCyc:2.6.1.49-RXN
xref: RHEA:15273
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.49
+property_value: skos:exactMatch RHEA:15273
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047310
@@ -295853,6 +305765,9 @@
xref: MetaCyc:2.6.1.50-RXN
xref: RHEA:22920
is_a: GO:0070548 ! L-glutamine aminotransferase activity
+property_value: skos:exactMatch EC:2.6.1.50
+property_value: skos:exactMatch RHEA:22920
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047311
@@ -295868,6 +305783,9 @@
xref: MetaCyc:2.6.1.56-RXN
xref: RHEA:15497
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.56
+property_value: skos:exactMatch RHEA:15497
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047312
@@ -295886,9 +305804,11 @@
synonym: "phenylalanine(histidine):pyruvate aminotransferase activity" BROAD [EC:2.6.1.58]
xref: KEGG_REACTION:R00692
xref: MetaCyc:2.6.1.58-RXN
-xref: Reactome:R-HSA-893593 "phenylalanine + pyruvate => keto-phenylpyruvate + alanine"
+xref: Reactome:R-HSA-893593 "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine"
xref: RHEA:13053
is_a: GO:0008793 ! aromatic-amino-acid transaminase activity
+property_value: skos:broadMatch EC:2.6.1.58
+property_value: skos:exactMatch RHEA:13053
[Term]
id: GO:0047313
@@ -295902,6 +305822,9 @@
xref: MetaCyc:2.6.1.60-RXN
xref: RHEA:10900
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.60
+property_value: skos:exactMatch RHEA:10900
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047315
@@ -295916,6 +305839,9 @@
xref: MetaCyc:2.6.1.63-RXN
xref: RHEA:19249
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.63
+property_value: skos:exactMatch RHEA:19249
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047316
@@ -295931,6 +305857,9 @@
xref: MetaCyc:2.6.1.64-RXN
xref: RHEA:17593
is_a: GO:0070548 ! L-glutamine aminotransferase activity
+property_value: skos:exactMatch EC:2.6.1.64
+property_value: skos:exactMatch RHEA:17593
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047317
@@ -295945,6 +305874,9 @@
xref: MetaCyc:2.6.1.65-RXN
xref: RHEA:16889
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.65
+property_value: skos:exactMatch RHEA:16889
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047319
@@ -295959,6 +305891,8 @@
xref: MetaCyc:2.6.1.70-RXN
xref: RHEA:14097
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.70
+property_value: skos:exactMatch RHEA:14097
[Term]
id: GO:0047320
@@ -295973,6 +305907,9 @@
xref: MetaCyc:2.6.1.72-RXN
xref: RHEA:15589
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.72
+property_value: skos:exactMatch RHEA:15589
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047321
@@ -295989,6 +305926,8 @@
xref: MetaCyc:2.7.99.1-RXN
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.99.1
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047322
@@ -296010,8 +305949,15 @@
synonym: "STK29" RELATED [EC:2.7.11.31]
xref: EC:2.7.11.31
xref: MetaCyc:2.7.1.109-RXN
+xref: RHEA:20333
+xref: RHEA:23172
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:exactMatch EC:2.7.11.31
+property_value: skos:narrowMatch RHEA:20333
+property_value: skos:narrowMatch RHEA:23172
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27664" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0047323
@@ -296031,9 +305977,13 @@
synonym: "STK2" RELATED [EC:2.7.11.4]
xref: EC:2.7.11.4
xref: MetaCyc:2.7.11.4-RXN
+xref: Reactome:R-HSA-5693148 "BCKDK phosphorylates BCKDH"
xref: Reactome:R-HSA-9912480 "BCKDK loss-of-function mutations do not phosphorylate BCKDH"
xref: RHEA:17301
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:exactMatch EC:2.7.11.4
+property_value: skos:exactMatch MetaCyc:2.7.11.4-RXN
+property_value: skos:exactMatch RHEA:17301
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28789" xsd:anyURI
[Term]
@@ -296048,6 +305998,9 @@
xref: RHEA:18381
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.121
+property_value: skos:exactMatch RHEA:18381
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047325
@@ -296069,6 +306022,10 @@
xref: Reactome:R-HSA-994137 "ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5"
xref: RHEA:12452
is_a: GO:0051765 ! inositol tetrakisphosphate kinase activity
+property_value: skos:exactMatch EC:2.7.1.134
+property_value: skos:exactMatch KEGG_REACTION:R03479
+property_value: skos:exactMatch MetaCyc:2.7.1.134-RXN
+property_value: skos:exactMatch RHEA:12452
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
[Term]
@@ -296086,6 +306043,11 @@
xref: Reactome:R-HSA-1855228 "I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus"
xref: RHEA:12717
is_a: GO:0051765 ! inositol tetrakisphosphate kinase activity
+property_value: skos:broadMatch EC:2.7.1.140
+property_value: skos:broadMatch EC:2.7.1.151
+property_value: skos:exactMatch KEGG_REACTION:R03478
+property_value: skos:exactMatch MetaCyc:2.7.1.140-RXN
+property_value: skos:exactMatch RHEA:12717
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
[Term]
@@ -296100,6 +306062,9 @@
xref: RHEA:21288
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.142
+property_value: skos:exactMatch RHEA:21288
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047328
@@ -296113,6 +306078,9 @@
xref: RHEA:13077
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.61
+property_value: skos:exactMatch RHEA:13077
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047329
@@ -296127,6 +306095,9 @@
xref: RHEA:10972
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.62
+property_value: skos:exactMatch RHEA:10972
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047330
@@ -296142,6 +306113,9 @@
xref: RHEA:22036
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.63
+property_value: skos:exactMatch RHEA:22036
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047331
@@ -296157,6 +306131,9 @@
xref: RHEA:13689
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.79
+property_value: skos:exactMatch RHEA:13689
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047332
@@ -296172,6 +306149,9 @@
xref: RHEA:23764
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.80
+property_value: skos:exactMatch RHEA:23764
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047333
@@ -296187,6 +306167,9 @@
xref: MetaCyc:2.7.1.88-RXN
xref: RHEA:16281
is_a: GO:0034071 ! aminoglycoside phosphotransferase activity
+property_value: skos:exactMatch EC:2.7.1.88
+property_value: skos:exactMatch RHEA:16281
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047334
@@ -296207,6 +306190,9 @@
xref: MetaCyc:2.7.1.90-RXN
xref: RHEA:13613
is_a: GO:0008443 ! phosphofructokinase activity
+property_value: skos:exactMatch EC:2.7.1.90
+property_value: skos:exactMatch RHEA:13613
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047335
@@ -296220,6 +306206,9 @@
xref: MetaCyc:2.7.4.17-RXN
xref: RHEA:18665
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
+property_value: skos:exactMatch EC:2.7.4.17
+property_value: skos:exactMatch RHEA:18665
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047336
@@ -296233,6 +306222,9 @@
xref: RHEA:11396
is_a: GO:0016301 ! kinase activity
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
+property_value: skos:exactMatch EC:2.7.4.19
+property_value: skos:exactMatch RHEA:11396
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047337
@@ -296245,6 +306237,9 @@
xref: MetaCyc:2.7.4.20-RXN
xref: RHEA:19417
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
+property_value: skos:exactMatch EC:2.7.4.20
+property_value: skos:exactMatch RHEA:19417
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047338
@@ -296262,6 +306257,9 @@
xref: MetaCyc:2.7.7.11-RXN
xref: RHEA:18389
is_a: GO:0051748 ! UTP-monosaccharide-1-phosphate uridylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.11
+property_value: skos:exactMatch RHEA:18389
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047339
@@ -296287,6 +306285,8 @@
xref: EC:2.7.7.28
xref: MetaCyc:2.7.7.28-RXN
is_a: GO:0016779 ! nucleotidyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.28
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047341
@@ -296307,6 +306307,9 @@
xref: Reactome:R-HSA-6787533 "FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc"
xref: RHEA:13549
is_a: GO:0070568 ! guanylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.30
+property_value: skos:exactMatch RHEA:13549
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047342
@@ -296325,6 +306328,9 @@
xref: MetaCyc:2.7.7.32-RXN
xref: RHEA:17165
is_a: GO:0016779 ! nucleotidyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.32
+property_value: skos:exactMatch RHEA:17165
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047343
@@ -296345,6 +306351,9 @@
xref: MetaCyc:2.7.7.33-RXN
xref: RHEA:18213
is_a: GO:0070567 ! cytidylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.33
+property_value: skos:exactMatch RHEA:18213
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047344
@@ -296362,6 +306371,9 @@
xref: MetaCyc:2.7.7.34-RXN
xref: RHEA:10708
is_a: GO:0070568 ! guanylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.34
+property_value: skos:exactMatch RHEA:10708
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047345
@@ -296378,6 +306390,9 @@
xref: MetaCyc:2.7.7.35-RXN
xref: RHEA:14529
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.35
+property_value: skos:exactMatch RHEA:14529
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047346
@@ -296396,6 +306411,8 @@
xref: EC:2.7.7.36
xref: MetaCyc:2.7.7.36-RXN
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.36
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047347
@@ -296417,6 +306434,8 @@
xref: EC:2.7.7.37
xref: MetaCyc:2.7.7.37-RXN
is_a: GO:0016779 ! nucleotidyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.37
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047348
@@ -296436,6 +306455,9 @@
xref: MetaCyc:2.7.7.39-RXN
xref: RHEA:13361
is_a: GO:0070567 ! cytidylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.39
+property_value: skos:exactMatch RHEA:13361
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047349
@@ -296452,9 +306474,11 @@
xref: EC:2.7.7.40
xref: KEGG_REACTION:R02921
xref: MetaCyc:2.7.7.40-RXN
-xref: Reactome:R-HSA-9940844 "CRPPA dimer transfers cytidylyl to Rbt5P"
xref: RHEA:12456
is_a: GO:0070567 ! cytidylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.40
+property_value: skos:exactMatch RHEA:12456
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047350
@@ -296472,6 +306496,9 @@
xref: MetaCyc:2.7.7.44-RXN
xref: RHEA:16325
is_a: GO:0070569 ! uridylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.44
+property_value: skos:exactMatch RHEA:16325
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047351
@@ -296485,6 +306512,9 @@
xref: MetaCyc:2.7.7.45-RXN
xref: RHEA:18153
is_a: GO:0070568 ! guanylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.45
+property_value: skos:exactMatch RHEA:18153
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047352
@@ -296499,6 +306529,9 @@
xref: MetaCyc:2.7.7.51-RXN
xref: RHEA:19197
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.51
+property_value: skos:exactMatch RHEA:19197
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047353
@@ -296514,6 +306547,9 @@
xref: MetaCyc:2.7.7.57-RXN
xref: RHEA:10576
is_a: GO:0070567 ! cytidylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.57
+property_value: skos:exactMatch RHEA:10576
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047354
@@ -296530,6 +306566,9 @@
xref: MetaCyc:2.7.8.10-RXN
xref: RHEA:21224
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.10
+property_value: skos:exactMatch RHEA:21224
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047355
@@ -296548,6 +306587,9 @@
xref: MetaCyc:TEICHOICSYN4-RXN
xref: RHEA:13565
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.12
+property_value: skos:exactMatch RHEA:13565
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047356
@@ -296566,6 +306608,9 @@
xref: MetaCyc:RXN-18380
xref: RHEA:13353
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.14
+property_value: skos:exactMatch RHEA:13353
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047357
@@ -296583,6 +306628,9 @@
xref: MetaCyc:2.7.8.18-RXN
xref: RHEA:22440
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.18
+property_value: skos:exactMatch RHEA:22440
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047358
@@ -296600,6 +306648,9 @@
xref: MetaCyc:2.7.8.19-RXN
xref: RHEA:20181
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.19
+property_value: skos:exactMatch RHEA:20181
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047359
@@ -296612,6 +306663,9 @@
xref: MetaCyc:2.7.8.22-RXN
xref: RHEA:36227
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.22
+property_value: skos:exactMatch RHEA:36227
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047360
@@ -296628,6 +306682,9 @@
xref: MetaCyc:2.7.8.6-RXN
xref: RHEA:11652
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.6
+property_value: skos:exactMatch RHEA:11652
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047361
@@ -296638,6 +306695,8 @@
xref: EC:2.7.8.9
xref: MetaCyc:2.7.8.9-RXN
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.9
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047362
@@ -296652,6 +306711,9 @@
xref: MetaCyc:2.8.1.5-RXN
xref: RHEA:15121
is_a: GO:0016783 ! sulfurtransferase activity
+property_value: skos:exactMatch EC:2.8.1.5
+property_value: skos:exactMatch RHEA:15121
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047363
@@ -296665,6 +306727,9 @@
xref: MetaCyc:2.8.2.19-RXN
xref: RHEA:13273
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.19
+property_value: skos:exactMatch RHEA:13273
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047364
@@ -296677,7 +306742,20 @@
synonym: "desulphoglucosinolate sulphotransferase activity" EXACT []
synonym: "PAPS-desulfoglucosinolate sulfotransferase activity" RELATED [EC:2.8.2.24]
xref: EC:2.8.2.24
+xref: KEGG_REACTION:R03214
+xref: KEGG_REACTION:R08167
+xref: MetaCyc:RXN-1443
+xref: MetaCyc:RXN-4606
+xref: RHEA:20281
+xref: RHEA:52736
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.24
+property_value: skos:narrowMatch KEGG_REACTION:R03214
+property_value: skos:narrowMatch KEGG_REACTION:R08167
+property_value: skos:narrowMatch MetaCyc:RXN-1443
+property_value: skos:narrowMatch MetaCyc:RXN-4606
+property_value: skos:narrowMatch RHEA:20281
+property_value: skos:narrowMatch RHEA:52736
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28853" xsd:anyURI
[Term]
@@ -296695,6 +306773,9 @@
xref: MetaCyc:2.8.2.26-RXN
xref: RHEA:22504
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.26
+property_value: skos:exactMatch RHEA:22504
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047366
@@ -296710,6 +306791,9 @@
xref: MetaCyc:2.8.2.27-RXN
xref: RHEA:17205
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.27
+property_value: skos:exactMatch RHEA:17205
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047367
@@ -296725,6 +306809,9 @@
xref: MetaCyc:2.8.2.28-RXN
xref: RHEA:21860
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.28
+property_value: skos:exactMatch RHEA:21860
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047368
@@ -296740,6 +306827,9 @@
xref: MetaCyc:2.8.2.7-RXN
xref: RHEA:14337
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.7
+property_value: skos:exactMatch RHEA:14337
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047369
@@ -296753,6 +306843,9 @@
xref: MetaCyc:2.8.3.13-RXN
xref: RHEA:12284
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.13
+property_value: skos:exactMatch RHEA:12284
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047370
@@ -296766,6 +306859,8 @@
xref: MetaCyc:2.8.3.7-RXN
xref: RHEA:38287
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch RHEA:38287
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047371
@@ -296780,6 +306875,9 @@
xref: MetaCyc:2.8.3.9-RXN
xref: RHEA:12961
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.9
+property_value: skos:exactMatch RHEA:12961
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047372
@@ -296811,6 +306909,10 @@
xref: RHEA:15245
is_a: GO:0016298 ! lipase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:broadMatch EC:3.1.1.79
+property_value: skos:exactMatch EC:3.1.1.23
+property_value: skos:exactMatch MetaCyc:RXN-19280
+property_value: skos:exactMatch RHEA:15245
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28339" xsd:anyURI
[Term]
@@ -296827,6 +306929,9 @@
xref: RHEA:11548
is_a: GO:0019213 ! deacetylase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.54
+property_value: skos:exactMatch RHEA:11548
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047374
@@ -296841,6 +306946,9 @@
xref: RHEA:12208
is_a: GO:0019213 ! deacetylase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.56
+property_value: skos:exactMatch RHEA:12208
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047375
@@ -296855,6 +306963,8 @@
xref: MetaCyc:3.1.1.58-RXN
is_a: GO:0019213 ! deacetylase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.58
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047376
@@ -296870,8 +306980,10 @@
xref: Reactome:R-HSA-2429643 "NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs"
xref: RHEA:13933
is_a: GO:0050253 ! retinyl-palmitate esterase activity
+property_value: skos:exactMatch RHEA:13933
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24923" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047377
@@ -296887,6 +306999,9 @@
xref: RHEA:16313
is_a: GO:0019213 ! deacetylase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.66
+property_value: skos:exactMatch RHEA:16313
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047378
@@ -296900,6 +307015,9 @@
xref: MetaCyc:3.1.1.71-RXN
xref: RHEA:11552
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.71
+property_value: skos:exactMatch RHEA:11552
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047379
@@ -296959,6 +307077,9 @@
xref: MetaCyc:3.1.3.14-RXN
xref: RHEA:16081
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.14
+property_value: skos:exactMatch RHEA:16081
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047383
@@ -296973,6 +307094,9 @@
xref: MetaCyc:3.1.3.40-RXN
xref: RHEA:15777
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.40
+property_value: skos:exactMatch RHEA:15777
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047384
@@ -296985,6 +307109,8 @@
xref: EC:3.1.3.47
xref: MetaCyc:3.1.3.47-RXN
is_a: GO:0004721 ! phosphoprotein phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.47
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047385
@@ -296996,10 +307122,12 @@
synonym: "branched-chain oxo-acid dehydrogenase phosphatase activity" EXACT []
xref: EC:3.1.3.52
xref: MetaCyc:3.1.3.52-RXN
-xref: Reactome:R-HSA-5693153 "PPM1K dephosphorylates p-BCKDH"
xref: RHEA:77247
is_a: GO:0004721 ! phosphoprotein phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.52
+property_value: skos:exactMatch RHEA:77247
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26088" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047386
@@ -297015,6 +307143,9 @@
xref: MetaCyc:3.1.3.54-RXN
xref: RHEA:13333
is_a: GO:0050308 ! sugar-phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.54
+property_value: skos:exactMatch RHEA:13333
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047387
@@ -297029,6 +307160,9 @@
xref: MetaCyc:3.1.4.13-RXN
xref: RHEA:17113
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.13
+property_value: skos:exactMatch RHEA:17113
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047388
@@ -297047,7 +307181,10 @@
xref: RHEA:43716
is_a: GO:0016779 ! nucleotidyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.7.7.89
+property_value: skos:exactMatch RHEA:43716
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25974" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047389
@@ -297065,6 +307202,9 @@
xref: Reactome:R-HSA-6814132 "GDPD5 hydrolyzes GPCho"
xref: RHEA:16061
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.2
+property_value: skos:exactMatch RHEA:16061
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047390
@@ -297079,6 +307219,9 @@
xref: Reactome:R-HSA-6814797 "ENPP6 hydrolyzes lysophosphatidylcholine"
xref: RHEA:19545
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.38
+property_value: skos:exactMatch RHEA:19545
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047391
@@ -297091,6 +307234,9 @@
xref: MetaCyc:3.1.4.39-RXN
xref: RHEA:15965
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.39
+property_value: skos:exactMatch RHEA:15965
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047392
@@ -297109,6 +307255,9 @@
xref: MetaCyc:3.1.4.40-RXN
xref: RHEA:20185
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.40
+property_value: skos:exactMatch RHEA:20185
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047393
@@ -297122,6 +307271,9 @@
xref: MetaCyc:3.1.4.42-RXN
xref: RHEA:16493
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.42
+property_value: skos:exactMatch RHEA:16493
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047394
@@ -297139,6 +307291,9 @@
xref: MetaCyc:3.1.4.43-RXN
xref: RHEA:14033
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.43
+property_value: skos:exactMatch RHEA:14033
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047395
@@ -297154,6 +307309,9 @@
xref: Reactome:R-HSA-6813740 "GDE1 hydrolyzes GroPIns"
xref: RHEA:16501
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.44
+property_value: skos:exactMatch RHEA:16501
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047396
@@ -297174,6 +307332,9 @@
xref: MetaCyc:3.1.4.47-RXN
xref: RHEA:14333
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
+property_value: skos:exactMatch EC:4.6.1.14
+property_value: skos:exactMatch RHEA:14333
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047397
@@ -297188,6 +307349,9 @@
xref: MetaCyc:3.1.4.48-RXN
xref: RHEA:13857
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.48
+property_value: skos:exactMatch RHEA:13857
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047398
@@ -297200,6 +307364,9 @@
xref: MetaCyc:3.1.4.49-RXN
xref: RHEA:12989
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.49
+property_value: skos:exactMatch RHEA:12989
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047399
@@ -297213,6 +307380,9 @@
xref: RHEA:18045
is_a: GO:0008081 ! phosphoric diester hydrolase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:3.1.4.51
+property_value: skos:exactMatch RHEA:18045
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047400
@@ -297224,7 +307394,10 @@
xref: KEGG_REACTION:R00318
xref: MetaCyc:3.11.1.2-RXN
xref: RHEA:16749
-is_a: GO:0016827 ! hydrolase activity, acting on acid carbon-phosphorus bonds
+is_a: GO:0016827 ! hydrolase activity, acting on carbon-phosphorus bonds
+property_value: skos:exactMatch EC:3.11.1.2
+property_value: skos:exactMatch RHEA:16749
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047401
@@ -297236,7 +307409,10 @@
xref: KEGG_REACTION:R01930
xref: MetaCyc:3.12.1.1-RXN
xref: RHEA:21884
-is_a: GO:0016828 ! hydrolase activity, acting on acid sulfur-sulfur bonds
+is_a: GO:0016828 ! hydrolase activity, acting on sulfur-sulfur bonds
+property_value: skos:exactMatch EC:3.12.1.1
+property_value: skos:exactMatch RHEA:21884
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047402
@@ -297250,6 +307426,9 @@
xref: RHEA:11068
is_a: GO:0015926 ! glucosidase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:3.2.1.107
+property_value: skos:exactMatch RHEA:11068
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047403
@@ -297261,7 +307440,10 @@
xref: MetaCyc:RXN-8731
xref: RHEA:21568
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.140
+property_value: skos:exactMatch RHEA:21568
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047404
@@ -297275,6 +307457,9 @@
xref: MetaCyc:RXN-16484
xref: RHEA:15073
is_a: GO:0046574 ! glucuronidase activity
+property_value: skos:exactMatch EC:3.2.1.56
+property_value: skos:exactMatch RHEA:15073
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30698" xsd:anyURI
[Term]
@@ -297289,6 +307474,9 @@
xref: MetaCyc:3.2.2.10-RXN
xref: RHEA:13425
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.2.10
+property_value: skos:exactMatch RHEA:13425
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047406
@@ -297302,6 +307490,9 @@
xref: MetaCyc:3.2.2.11-RXN
xref: RHEA:12324
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.2.11
+property_value: skos:exactMatch RHEA:12324
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047407
@@ -297319,6 +307510,9 @@
xref: MetaCyc:3.2.2.24-RXN
xref: RHEA:14493
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.2.24
+property_value: skos:exactMatch RHEA:14493
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047408
@@ -297331,6 +307525,9 @@
xref: MetaCyc:3.3.2.2-RXN
xref: RHEA:22544
is_a: GO:0016803 ! ether hydrolase activity
+property_value: skos:exactMatch EC:3.3.2.2
+property_value: skos:exactMatch RHEA:22544
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047409
@@ -297364,6 +307561,9 @@
xref: MetaCyc:3.5.1.29-RXN
xref: RHEA:10432
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.29
+property_value: skos:exactMatch RHEA:10432
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047412
@@ -297377,6 +307577,9 @@
xref: MetaCyc:3.5.1.60-RXN
xref: RHEA:17505
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.60
+property_value: skos:exactMatch RHEA:17505
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047413
@@ -297393,6 +307596,9 @@
xref: MetaCyc:3.5.1.64-RXN
xref: RHEA:18901
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.64
+property_value: skos:exactMatch RHEA:18901
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047414
@@ -297408,6 +307614,9 @@
xref: RHEA:17677
xref: Wikipedia:2-(hydroxymethyl)-3-(acetamidomethylene)succinate_amidohydrolase_(deaminating\,_decarboxylating)
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.66
+property_value: skos:exactMatch RHEA:17677
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047415
@@ -297422,6 +307631,9 @@
xref: MetaCyc:3.5.1.72-RXN
xref: RHEA:14421
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.72
+property_value: skos:exactMatch RHEA:14421
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047416
@@ -297434,6 +307646,9 @@
xref: MetaCyc:3.5.1.76-RXN
xref: RHEA:10352
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.76
+property_value: skos:exactMatch RHEA:10352
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047417
@@ -297445,6 +307660,9 @@
xref: MetaCyc:3.5.1.77-RXN
xref: RHEA:11000
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.77
+property_value: skos:exactMatch RHEA:11000
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047418
@@ -297457,6 +307675,9 @@
xref: MetaCyc:3.5.1.79-RXN
xref: RHEA:18297
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.79
+property_value: skos:exactMatch RHEA:18297
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047419
@@ -297467,6 +307688,7 @@
xref: RHEA:18149
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0019213 ! deacetylase activity
+property_value: skos:exactMatch RHEA:18149
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -297480,6 +307702,9 @@
xref: MetaCyc:3.5.1.81-RXN
xref: RHEA:18309
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.81
+property_value: skos:exactMatch RHEA:18309
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047421
@@ -297492,6 +307717,9 @@
xref: MetaCyc:3.5.1.82-RXN
xref: RHEA:12833
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.82
+property_value: skos:exactMatch RHEA:12833
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047422
@@ -297504,6 +307732,9 @@
xref: MetaCyc:3.5.1.83-RXN
xref: RHEA:18285
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.83
+property_value: skos:exactMatch RHEA:18285
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047423
@@ -297522,6 +307753,9 @@
xref: RHEA:11720
xref: Wikipedia:N-methylhydantoinase_(ATP-hydrolysing)
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.14
+property_value: skos:exactMatch RHEA:11720
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047424
@@ -297535,6 +307769,9 @@
xref: RHEA:15929
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.3.21
+property_value: skos:exactMatch RHEA:15929
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047425
@@ -297549,6 +307786,9 @@
xref: RHEA:10560
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.22
+property_value: skos:exactMatch RHEA:10560
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047426
@@ -297560,6 +307800,9 @@
xref: MetaCyc:3.5.5.2-RXN
xref: RHEA:22704
is_a: GO:0000257 ! nitrilase activity
+property_value: skos:exactMatch EC:3.5.5.2
+property_value: skos:exactMatch RHEA:22704
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047427
@@ -297573,6 +307816,9 @@
xref: MetaCyc:3.5.5.4-RXN
xref: RHEA:11188
is_a: GO:0000257 ! nitrilase activity
+property_value: skos:exactMatch EC:3.5.5.4
+property_value: skos:exactMatch RHEA:11188
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047428
@@ -297584,6 +307830,9 @@
xref: MetaCyc:3.5.5.5-RXN
xref: RHEA:20657
is_a: GO:0000257 ! nitrilase activity
+property_value: skos:exactMatch EC:3.5.5.5
+property_value: skos:exactMatch RHEA:20657
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047429
@@ -297596,9 +307845,15 @@
xref: EC:3.6.1.9
xref: MetaCyc:NUCLEOTIDE-PYROPHOSPHATASE-RXN
xref: Reactome:R-HSA-9755030 "ITPA dimer dephosphorylates RBV-TP to RBV-MP"
+xref: RHEA:23996
+xref: RHEA:44644
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.9
+property_value: skos:narrowMatch RHEA:23996
+property_value: skos:narrowMatch RHEA:44644
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27991" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047430
@@ -297611,6 +307866,9 @@
xref: MetaCyc:3.6.1.44-RXN
xref: RHEA:15205
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.44
+property_value: skos:exactMatch RHEA:15205
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047431
@@ -297624,6 +307882,9 @@
xref: MetaCyc:4.1.1.51-RXN
xref: RHEA:13669
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.51
+property_value: skos:exactMatch RHEA:13669
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047432
@@ -297642,6 +307903,9 @@
xref: MetaCyc:4.1.1.64-RXN
xref: RHEA:16073
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.64
+property_value: skos:exactMatch RHEA:16073
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047433
@@ -297659,6 +307923,9 @@
xref: MetaCyc:4.1.1.72-RXN
xref: RHEA:21108
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.72
+property_value: skos:exactMatch RHEA:21108
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047434
@@ -297673,6 +307940,9 @@
xref: MetaCyc:4.1.1.74-RXN
xref: RHEA:18017
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.74
+property_value: skos:exactMatch RHEA:18017
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047435
@@ -297689,6 +307959,9 @@
xref: MetaCyc:4.1.1.75-RXN
xref: RHEA:11340
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.75
+property_value: skos:exactMatch RHEA:11340
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047436
@@ -297704,6 +307977,9 @@
xref: MetaCyc:4.1.1.76-RXN
xref: RHEA:20513
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.76
+property_value: skos:exactMatch RHEA:20513
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047437
@@ -297717,6 +307993,9 @@
xref: RHEA:24260
xref: UM-BBD_reactionID:r1435
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.77
+property_value: skos:exactMatch RHEA:24260
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047438
@@ -297733,6 +308012,9 @@
xref: MetaCyc:4.1.2.18-RXN
xref: RHEA:18545
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.18
+property_value: skos:exactMatch RHEA:18545
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047439
@@ -297751,6 +308033,9 @@
xref: MetaCyc:4.1.2.23-RXN
xref: RHEA:23340
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.23
+property_value: skos:exactMatch RHEA:23340
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047440
@@ -297765,6 +308050,9 @@
xref: MetaCyc:4.1.2.28-RXN
xref: RHEA:20609
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.28
+property_value: skos:exactMatch RHEA:20609
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047441
@@ -297780,6 +308068,9 @@
xref: MetaCyc:4.1.2.29-RXN
xref: RHEA:13177
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.29
+property_value: skos:exactMatch RHEA:13177
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047442
@@ -297804,7 +308095,12 @@
synonym: "pyruvate aldolase activity" RELATED [EC:4.1.3.17]
xref: EC:4.1.3.17
xref: MetaCyc:4.1.3.17-RXN
+xref: RHEA:22748
+xref: RHEA:28935
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.17
+property_value: skos:narrowMatch RHEA:22748
+property_value: skos:narrowMatch RHEA:28935
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
[Term]
@@ -297825,6 +308121,9 @@
xref: Reactome:R-HSA-4084976 "NANS converts ManNAc-6-P to Neu5Ac-9-P"
xref: RHEA:13421
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.57
+property_value: skos:exactMatch RHEA:13421
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047445
@@ -297843,6 +308142,9 @@
xref: RHEA:23084
xref: UM-BBD_reactionID:r1168
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.26
+property_value: skos:exactMatch RHEA:23084
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047446
@@ -297856,6 +308158,9 @@
xref: MetaCyc:4.1.3.35-RXN
xref: RHEA:23868
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.35
+property_value: skos:exactMatch RHEA:23868
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047447
@@ -297873,6 +308178,9 @@
xref: MetaCyc:4.3.1.20-RXN
xref: RHEA:19757
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.20
+property_value: skos:exactMatch RHEA:19757
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047448
@@ -297889,6 +308197,9 @@
xref: MetaCyc:4.2.1.41-RXN
xref: RHEA:24608
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.41
+property_value: skos:exactMatch RHEA:24608
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047449
@@ -297903,6 +308214,9 @@
xref: MetaCyc:4.2.1.43-RXN
xref: RHEA:17201
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.43
+property_value: skos:exactMatch RHEA:17201
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047450
@@ -297951,6 +308265,9 @@
xref: MetaCyc:4.2.1.73-RXN
xref: RHEA:23876
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.73
+property_value: skos:exactMatch RHEA:23876
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047453
@@ -297966,8 +308283,14 @@
xref: KEGG_REACTION:R00129
xref: MetaCyc:4.2.1.93-RXN
xref: Reactome:R-HSA-6806967 "CARKD dehydrates S-NAD(P)HX to NADPH"
+xref: RHEA:19017
+xref: RHEA:32231
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.93
+property_value: skos:narrowMatch RHEA:19017
+property_value: skos:narrowMatch RHEA:32231
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047454
@@ -297981,6 +308304,9 @@
xref: MetaCyc:4.2.1.97-RXN
xref: RHEA:19769
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.97
+property_value: skos:exactMatch RHEA:19769
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047455
@@ -298001,6 +308327,9 @@
xref: MetaCyc:4.2.1.98-RXN
xref: RHEA:12584
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.98
+property_value: skos:exactMatch RHEA:12584
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047456
@@ -298014,6 +308343,9 @@
xref: MetaCyc:4.2.1.99-RXN
xref: RHEA:17941
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.99
+property_value: skos:exactMatch RHEA:17941
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047457
@@ -298030,6 +308362,8 @@
xref: EC:4.2.2.13
xref: MetaCyc:4.2.2.13-RXN
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.13
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047458
@@ -298051,6 +308385,8 @@
xref: MetaCyc:2.5.1.51-RXN
xref: RHEA:13117
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.51
+property_value: skos:exactMatch RHEA:13117
[Term]
id: GO:0047459
@@ -298065,6 +308401,9 @@
xref: MetaCyc:4.3.1.14-RXN
xref: RHEA:10056
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.14
+property_value: skos:exactMatch RHEA:10056
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047460
@@ -298079,6 +308418,9 @@
xref: MetaCyc:4.5.1.4-RXN
xref: RHEA:11620
is_a: GO:0016848 ! carbon-halide lyase activity
+property_value: skos:exactMatch EC:4.5.1.4
+property_value: skos:exactMatch RHEA:11620
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047461
@@ -298091,6 +308433,9 @@
xref: MetaCyc:4.6.1.11-RXN
xref: RHEA:19525
is_a: GO:0010334 ! sesquiterpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.13
+property_value: skos:exactMatch RHEA:19525
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047462
@@ -298106,6 +308451,9 @@
xref: MetaCyc:5.1.1.11-RXN
xref: RHEA:20201
is_a: GO:0047661 ! amino-acid racemase activity
+property_value: skos:exactMatch EC:5.1.1.11
+property_value: skos:exactMatch RHEA:20201
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047463
@@ -298119,6 +308467,9 @@
xref: MetaCyc:5.1.1.15-RXN
xref: RHEA:14813
is_a: GO:0016855 ! racemase and epimerase activity, acting on amino acids and derivatives
+property_value: skos:exactMatch EC:5.1.1.15
+property_value: skos:exactMatch RHEA:14813
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047464
@@ -298138,7 +308489,10 @@
xref: Reactome:R-HSA-2076371 "GLCE epimerises more GlcA to IdoA as sulfate content rises"
xref: RHEA:20197
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.17
+property_value: skos:exactMatch RHEA:20197
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28762" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047465
@@ -298155,6 +308509,8 @@
xref: MetaCyc:5.1.3.9-RXN
xref: RHEA:23932
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.9
+property_value: skos:exactMatch RHEA:23932
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -298172,6 +308528,9 @@
xref: RHEA:10924
xref: UM-BBD_reactionID:r0278
is_a: GO:0016859 ! cis-trans isomerase activity
+property_value: skos:exactMatch EC:5.2.1.10
+property_value: skos:exactMatch RHEA:10924
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047467
@@ -298192,6 +308551,8 @@
xref: EC:5.4.2.5
xref: MetaCyc:RXN-16999
is_a: GO:0004614 ! phosphoglucomutase activity
+property_value: skos:exactMatch EC:5.4.2.5
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047469
@@ -298208,6 +308569,9 @@
xref: MetaCyc:5.4.99.14-RXN
xref: RHEA:19237
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.14
+property_value: skos:exactMatch RHEA:19237
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047470
@@ -298221,6 +308585,9 @@
xref: MetaCyc:5.4.99.15-RXN
xref: RHEA:13621
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.15
+property_value: skos:exactMatch RHEA:13621
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047471
@@ -298234,6 +308601,9 @@
xref: MetaCyc:5.4.99.16-RXN
xref: RHEA:15145
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.16
+property_value: skos:exactMatch RHEA:15145
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047472
@@ -298252,7 +308622,10 @@
xref: RHEA:23656
xref: UM-BBD_reactionID:r0582
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.2
+property_value: skos:exactMatch RHEA:23656
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21794" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047473
@@ -298281,7 +308654,10 @@
xref: MetaCyc:6.2.1.19-RXN
xref: RHEA:20101
is_a: GO:0015645 ! fatty acid ligase activity
+property_value: skos:exactMatch EC:6.2.1.19
+property_value: skos:exactMatch RHEA:20101
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047475
@@ -298299,6 +308675,9 @@
xref: RHEA:20956
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.30
+property_value: skos:exactMatch RHEA:20956
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047476
@@ -298314,6 +308693,9 @@
xref: RHEA:21776
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.28
+property_value: skos:exactMatch RHEA:21776
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047478
@@ -298328,6 +308710,9 @@
xref: MetaCyc:6.3.1.4-RXN
xref: RHEA:14197
is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity
+property_value: skos:exactMatch EC:6.3.1.4
+property_value: skos:exactMatch RHEA:14197
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047479
@@ -298340,6 +308725,9 @@
xref: MetaCyc:6.3.1.9-RXN
xref: RHEA:21532
is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity
+property_value: skos:exactMatch EC:6.3.1.9
+property_value: skos:exactMatch RHEA:21532
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047480
@@ -298364,6 +308752,9 @@
xref: MetaCyc:6.3.2.10-RXN
xref: RHEA:16085
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.10
+property_value: skos:exactMatch RHEA:16085
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047481
@@ -298379,6 +308770,8 @@
xref: EC:6.3.2.16
xref: MetaCyc:6.3.2.16-RXN
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.16
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047482
@@ -298396,6 +308789,9 @@
xref: MetaCyc:6.3.2.7-RXN
xref: RHEA:17969
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.7
+property_value: skos:exactMatch RHEA:17969
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047483
@@ -298409,6 +308805,9 @@
xref: MetaCyc:6.3.4.8-RXN
xref: RHEA:16485
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.8
+property_value: skos:exactMatch RHEA:16485
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047484
@@ -298457,6 +308856,9 @@
xref: MetaCyc:OLIGOGALACTURONIDE-LYASE-RXN
xref: RHEA:20269
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.6
+property_value: skos:exactMatch RHEA:20269
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047488
@@ -298469,6 +308871,8 @@
xref: EC:4.2.2.7
xref: MetaCyc:4.2.2.7-RXN
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.7
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047489
@@ -298490,6 +308894,9 @@
xref: MetaCyc:4.2.2.9-RXN
xref: RHEA:57104
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.9
+property_value: skos:exactMatch RHEA:57104
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047490
@@ -298508,6 +308915,8 @@
xref: EC:4.2.2.10
xref: MetaCyc:RXN-19781
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.10
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047491
@@ -298524,6 +308933,8 @@
xref: EC:4.2.2.11
xref: MetaCyc:4.2.2.11-RXN
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.11
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047492
@@ -298533,6 +308944,8 @@
xref: EC:4.2.2.12
xref: MetaCyc:4.2.2.12-RXN
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.12
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047493
@@ -298546,6 +308959,9 @@
xref: MetaCyc:CERAMIDE-CHOLINEPHOSPHOTRANSFERASE-RXN
xref: RHEA:16273
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.3
+property_value: skos:exactMatch RHEA:16273
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047494
@@ -298563,6 +308979,9 @@
xref: MetaCyc:SERINE-PHOSPHOETHANOLAMINE-SYNTHASE-RXN
xref: RHEA:22656
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.4
+property_value: skos:exactMatch RHEA:22656
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047495
@@ -298575,6 +308994,8 @@
xref: EC:2.7.8.21
xref: MetaCyc:PGLYCEROLTRANSII-RXN
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.21
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047496
@@ -298597,28 +309018,33 @@
[Term]
id: GO:0047498
-name: calcium-dependent phospholipase A2 activity
+name: obsolete calcium-dependent phospholipase A2 activity
namespace: molecular_function
-def: "Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+." [PMID:34831185]
+def: "OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+." [PMID:34831185]
+comment: This term was made obsolete because it represents information outside the scope of GO.
synonym: "calcium-dependent cytosolic phospholipase A2 activity" NARROW []
synonym: "calcium-dependent secreted phospholipase A2 activity" NARROW []
xref: Reactome:R-HSA-111881 "Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase"
xref: Reactome:R-HSA-111883 "PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine"
-is_a: GO:0004623 ! phospholipase A2 activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31061" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0004623
[Term]
id: GO:0047499
-name: calcium-independent phospholipase A2 activity
+name: obsolete calcium-independent phospholipase A2 activity
namespace: molecular_function
-def: "Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+." [PMID:34831185]
-subset: goslim_chembl
+def: "OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+." [PMID:34831185]
+comment: This term was made obsolete because it represents information outside the scope of GO.
synonym: "calcium-independent cytosolic phospholipase A2 activity" NARROW []
xref: Reactome:R-HSA-8952251 "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)"
-is_a: GO:0004623 ! phospholipase A2 activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31061" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0004623
[Term]
id: GO:0047500
@@ -298633,6 +309059,10 @@
xref: RHEA:17329
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
relationship: part_of GO:0046211 ! (+)-camphor biosynthetic process
+property_value: skos:broadMatch RHEA:68828
+property_value: skos:exactMatch EC:1.1.1.198
+property_value: skos:exactMatch RHEA:17329
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047501
@@ -298646,6 +309076,9 @@
xref: MetaCyc:+-NEOMENTHOL-DEHYDROGENASE-RXN
xref: RHEA:23812
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.208
+property_value: skos:exactMatch RHEA:23812
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047502
@@ -298659,6 +309092,9 @@
xref: MetaCyc:+-SABINOL-DEHYDROGENASE-RXN
xref: RHEA:18329
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.228
+property_value: skos:exactMatch RHEA:18329
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047503
@@ -298671,6 +309107,10 @@
xref: MetaCyc:--BORNEOL-DEHYDROGENASE-RXN
xref: RHEA:22128
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch RHEA:68828
+property_value: skos:exactMatch EC:1.1.1.227
+property_value: skos:exactMatch RHEA:22128
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047504
@@ -298685,6 +309125,9 @@
xref: RHEA:13917
xref: UM-BBD_reactionID:r1182
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.207
+property_value: skos:exactMatch RHEA:13917
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047505
@@ -298698,6 +309141,9 @@
xref: MetaCyc:--MENTHOL-MONOOXYGENASE-RXN
xref: RHEA:11648
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.46
+property_value: skos:exactMatch RHEA:11648
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047506
@@ -298710,6 +309156,9 @@
xref: MetaCyc:DEOXYADENYLATE-KINASE-RXN
xref: RHEA:23100
is_a: GO:0047507 ! deoxynucleoside phosphate kinase activity, ATP as phosphate donor
+property_value: skos:exactMatch EC:2.7.4.11
+property_value: skos:exactMatch MetaCyc:DEOXYADENYLATE-KINASE-RXN
+property_value: skos:exactMatch RHEA:23100
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27917" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29533" xsd:anyURI
@@ -298728,7 +309177,10 @@
xref: RHEA:11216
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
is_a: GO:0019205 ! nucleobase-containing compound kinase activity
+property_value: skos:exactMatch EC:2.7.4.13
+property_value: skos:exactMatch RHEA:11216
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29533" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047508
@@ -298743,7 +309195,14 @@
synonym: "citramalate hydro-lyase activity" RELATED [EC:4.2.1.35]
xref: EC:4.2.1.35
xref: KEGG_REACTION:R03896
+xref: MetaCyc:R-2-METHYLMALATE-DEHYDRATASE-RXN
+xref: RHEA:22332
+xref: RHEA:42424
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.35
+property_value: skos:narrowMatch MetaCyc:R-2-METHYLMALATE-DEHYDRATASE-RXN
+property_value: skos:narrowMatch RHEA:22332
+property_value: skos:narrowMatch RHEA:42424
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
[Term]
@@ -298759,6 +309218,9 @@
xref: MetaCyc:R-DEHYDROPANTOATE-DEHYDROGENASE-RXN
xref: RHEA:19349
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.33
+property_value: skos:exactMatch RHEA:19349
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047510
@@ -298779,6 +309241,9 @@
xref: MetaCyc:S-2-METHYLMALATE-DEHYDRATASE-RXN
xref: RHEA:13529
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.34
+property_value: skos:exactMatch RHEA:13529
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047511
@@ -298791,6 +309256,9 @@
xref: MetaCyc:S-METHYLMALONYL-COA-HYDROLASE-RXN
xref: RHEA:17345
is_a: GO:0016289 ! acyl-CoA hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.17
+property_value: skos:exactMatch RHEA:17345
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047512
@@ -298806,6 +309274,9 @@
xref: MetaCyc:SS-BUTANEDIOL-DEHYDROGENASE-RXN
xref: RHEA:12184
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.76
+property_value: skos:exactMatch RHEA:12184
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047513
@@ -298820,6 +309291,9 @@
xref: MetaCyc:12-ALPHA-L-FUCOSIDASE-RXN
xref: RHEA:10816
is_a: GO:0004560 ! alpha-L-fucosidase activity
+property_value: skos:exactMatch EC:3.2.1.63
+property_value: skos:exactMatch RHEA:10816
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047514
@@ -298834,6 +309308,8 @@
xref: EC:2.4.1.97
xref: MetaCyc:13-BETA-GLUCAN-PHOSPHORYLASE-RXN
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.97
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047515
@@ -298847,6 +309323,9 @@
xref: MetaCyc:13-BETA-OLIGOGLUCAN-PHOSPHORYLASE-RXN
xref: RHEA:16041
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.30
+property_value: skos:exactMatch RHEA:16041
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047516
@@ -298862,6 +309341,9 @@
xref: MetaCyc:13-PROPANEDIOL-DEHYDROGENASE-RXN
xref: RHEA:23188
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.202
+property_value: skos:exactMatch RHEA:23188
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047517
@@ -298878,6 +309360,9 @@
xref: RHEA:15289
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.24
+property_value: skos:exactMatch RHEA:15289
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047518
@@ -298891,6 +309376,9 @@
xref: MetaCyc:1-METHYLADENOSINE-NUCLEOSIDASE-RXN
xref: RHEA:12865
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.2.13
+property_value: skos:exactMatch RHEA:12865
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047519
@@ -298905,6 +309393,9 @@
xref: MetaCyc:1.1.99.25-RXN
xref: RHEA:23672
is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.1.5.8
+property_value: skos:exactMatch RHEA:23672
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047520
@@ -298921,6 +309412,9 @@
xref: RHEA:19697
is_a: GO:0052689 ! carboxylic ester hydrolase activity
relationship: part_of GO:0042572 ! retinol metabolic process
+property_value: skos:exactMatch EC:3.1.1.63
+property_value: skos:exactMatch RHEA:19697
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047521
@@ -298936,6 +309430,9 @@
xref: MetaCyc:12-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN
xref: RHEA:21424
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.238
+property_value: skos:exactMatch RHEA:21424
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047522
@@ -298947,9 +309444,19 @@
synonym: "15-oxoprostaglandin 13-oxidase [NAD(P)+] activity" EXACT []
synonym: "15-oxoprostaglandin 13-oxidase activity" EXACT []
xref: EC:1.3.1.48
+xref: KEGG_REACTION:R04556
+xref: KEGG_REACTION:R04557
xref: MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN
xref: Reactome:R-HSA-2161692 "15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1"
+xref: RHEA:11912
+xref: RHEA:11916
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.48
+property_value: skos:exactMatch MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN
+property_value: skos:narrowMatch KEGG_REACTION:R04556
+property_value: skos:narrowMatch KEGG_REACTION:R04557
+property_value: skos:narrowMatch RHEA:11912
+property_value: skos:narrowMatch RHEA:11916
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28134" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
@@ -298963,6 +309470,9 @@
xref: MetaCyc:16-HYDROXYSTEROID-EPIMERASE-RXN
xref: RHEA:15829
is_a: GO:0016854 ! racemase and epimerase activity
+property_value: skos:exactMatch EC:5.1.99.2
+property_value: skos:exactMatch RHEA:15829
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047525
@@ -298978,6 +309488,9 @@
xref: MetaCyc:RXN-4502
xref: RHEA:17145
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.51
+property_value: skos:exactMatch RHEA:17145
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047526
@@ -298992,6 +309505,9 @@
xref: MetaCyc:RXN-3562
xref: RHEA:22560
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.45
+property_value: skos:exactMatch RHEA:22560
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047527
@@ -299005,6 +309521,9 @@
xref: MetaCyc:ENTMULTI-RXN
xref: RHEA:30571
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.14
+property_value: skos:exactMatch RHEA:30571
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047528
@@ -299017,6 +309536,9 @@
xref: MetaCyc:23-DIHYDROXYINDOLE-23-DIOXYGENASE-RXN
xref: RHEA:19445
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.23
+property_value: skos:exactMatch RHEA:19445
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047529
@@ -299031,6 +309553,9 @@
xref: MetaCyc:23-DIMETHYLMALATE-LYASE-RXN
xref: RHEA:10472
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.32
+property_value: skos:exactMatch RHEA:10472
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047530
@@ -299042,6 +309567,8 @@
xref: EC:1.4.1.12
xref: MetaCyc:24-DIAMINOPENTANOATE-DEHYDROGENASE-RXN
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.12
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047531
@@ -299066,6 +309593,9 @@
xref: MetaCyc:25-DIOXOPIPERAZINE-HYDROLASE-RXN
xref: RHEA:21808
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.13
+property_value: skos:exactMatch RHEA:21808
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047533
@@ -299079,6 +309609,9 @@
xref: MetaCyc:25-DIOXOVALERATE-DEHYDROGENASE-RXN
xref: RHEA:11296
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.26
+property_value: skos:exactMatch RHEA:11296
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047534
@@ -299092,6 +309625,9 @@
xref: MetaCyc:2-ACETOLACTATE-MUTASE-RXN
xref: RHEA:16361
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.3
+property_value: skos:exactMatch RHEA:16361
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047535
@@ -299104,6 +309640,9 @@
xref: MetaCyc:2-ALKYN-1-OL-DEHYDROGENASE-RXN
xref: RHEA:19101
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.165
+property_value: skos:exactMatch RHEA:19101
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047536
@@ -299123,6 +309662,9 @@
xref: Reactome:R-HSA-70952 "alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate"
xref: RHEA:12601
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.39
+property_value: skos:exactMatch RHEA:12601
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047537
@@ -299139,6 +309681,9 @@
xref: MetaCyc:2-AMINOHEXANOATE-AMINOTRANSFERASE-RXN
xref: RHEA:23600
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.67
+property_value: skos:exactMatch RHEA:23600
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047538
@@ -299153,6 +309698,9 @@
xref: MetaCyc:2-CARBOXY-D-ARABINITOL-1-PHOSPHATASE-RXN
xref: RHEA:17837
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.63
+property_value: skos:exactMatch RHEA:17837
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047539
@@ -299166,6 +309714,9 @@
xref: MetaCyc:2-DEOXYGLUCOSIDASE-RXN
xref: RHEA:15317
is_a: GO:0015926 ! glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.112
+property_value: skos:exactMatch RHEA:15317
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047540
@@ -299178,6 +309729,9 @@
xref: MetaCyc:2-ENOATE-REDUCTASE-RXN
xref: RHEA:10200
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.31
+property_value: skos:exactMatch RHEA:10200
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047541
@@ -299192,6 +309746,9 @@
xref: RHEA:19269
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.31
+property_value: skos:exactMatch RHEA:19269
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047542
@@ -299208,6 +309765,9 @@
xref: MetaCyc:2-FUROYL-COA-DEHYDROGENASE-RXN
xref: RHEA:21480
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.99.8
+property_value: skos:exactMatch RHEA:21480
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047543
@@ -299221,6 +309781,9 @@
xref: MetaCyc:2-HEXADECENAL-REDUCTASE-RXN
xref: RHEA:12444
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.27
+property_value: skos:exactMatch RHEA:12444
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047544
@@ -299230,8 +309793,18 @@
synonym: "2-hydroxybiphenyl,NADH:oxygen oxidoreductase (3-hydroxylating)" RELATED [EC:1.14.13.44]
xref: EC:1.14.13.44
xref: KEGG_REACTION:R03964
+xref: MetaCyc:2-HYDROXYBIPHENYL-3-MONOOXYGENASE-RXN
+xref: MetaCyc:RXN-13150
+xref: RHEA:11996
+xref: RHEA:63512
xref: UM-BBD_reactionID:r1423
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.44
+property_value: skos:exactMatch KEGG_REACTION:R03964
+property_value: skos:narrowMatch MetaCyc:2-HYDROXYBIPHENYL-3-MONOOXYGENASE-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-13150
+property_value: skos:narrowMatch RHEA:11996
+property_value: skos:narrowMatch RHEA:63512
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -299254,6 +309827,9 @@
xref: Reactome:R-HSA-880050 "(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2"
xref: RHEA:21252
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.2
+property_value: skos:exactMatch RHEA:21252
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30707" xsd:anyURI
[Term]
@@ -299269,6 +309845,9 @@
xref: RHEA:16973
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.26
+property_value: skos:exactMatch RHEA:16973
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047547
@@ -299284,6 +309863,9 @@
xref: MetaCyc:2-METHYLCITRATE-DEHYDRATASE-RXN
xref: RHEA:17725
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.79
+property_value: skos:exactMatch RHEA:17725
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047548
@@ -299297,6 +309879,9 @@
xref: MetaCyc:2-METHYLENEGLUTARATE-MUTASE-RXN
xref: RHEA:13793
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.4
+property_value: skos:exactMatch RHEA:13793
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047549
@@ -299312,6 +309897,9 @@
xref: RHEA:19457
xref: UM-BBD_reactionID:r1494
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.31
+property_value: skos:exactMatch RHEA:19457
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047550
@@ -299326,6 +309914,9 @@
xref: MetaCyc:2-OXOADIPATE-REDUCTASE-RXN
xref: RHEA:14793
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.172
+property_value: skos:exactMatch RHEA:14793
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047551
@@ -299344,6 +309935,9 @@
xref: RHEA:22276
xref: Wikipedia:2-oxoaldehyde_dehydrogenase_(NAD+)
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.23
+property_value: skos:exactMatch RHEA:22276
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047552
@@ -299360,6 +309954,9 @@
xref: MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NADP+-RXN
xref: RHEA:18129
is_a: GO:0033721 ! aldehyde dehydrogenase (NADP+) activity
+property_value: skos:exactMatch EC:1.2.1.49
+property_value: skos:exactMatch RHEA:18129
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047553
@@ -299378,6 +309975,9 @@
xref: MetaCyc:2-OXOGLUTARATE-SYNTHASE-RXN
xref: RHEA:17297
is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.2.7.3
+property_value: skos:exactMatch RHEA:17297
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047554
@@ -299390,6 +309990,9 @@
xref: MetaCyc:RXN-2462
xref: RHEA:10644
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.57
+property_value: skos:exactMatch RHEA:10644
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047555
@@ -299414,6 +310017,9 @@
xref: Reactome:R-HSA-74059 "PDE6 hydrolyses cGMP to GMP"
xref: RHEA:16957
is_a: GO:0004114 ! 3',5'-cyclic-nucleotide phosphodiesterase activity
+property_value: skos:exactMatch EC:3.1.4.35
+property_value: skos:exactMatch RHEA:16957
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047556
@@ -299430,6 +310036,9 @@
xref: RHEA:18601
xref: UM-BBD_reactionID:r1447
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.69
+property_value: skos:exactMatch RHEA:18601
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047557
@@ -299443,6 +310052,9 @@
xref: MetaCyc:3-ACI-NITROPROPANOATE-OXIDASE-RXN
xref: RHEA:22372
is_a: GO:0016663 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.7.3.5
+property_value: skos:exactMatch RHEA:22372
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047558
@@ -299460,6 +310072,9 @@
xref: MetaCyc:3-CYANOALANINE-HYDRATASE-RXN
xref: RHEA:15385
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.65
+property_value: skos:exactMatch RHEA:15385
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047559
@@ -299473,6 +310088,8 @@
xref: EC:1.1.1.130
xref: MetaCyc:3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.130
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047560
@@ -299494,6 +310111,9 @@
xref: Reactome:R-HSA-428123 "KDSR reduces 3-ketosphingoid"
xref: RHEA:22640
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.102
+property_value: skos:exactMatch RHEA:22640
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047561
@@ -299507,6 +310127,9 @@
xref: MetaCyc:3-HYDROXYANTHRANILATE-OXIDASE-RXN
xref: RHEA:17245
is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.10.3.5
+property_value: skos:exactMatch RHEA:17245
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047562
@@ -299523,7 +310146,10 @@
xref: MetaCyc:RXN-11769
xref: RHEA:14377
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.14
+property_value: skos:exactMatch RHEA:14377
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047563
@@ -299539,6 +310165,9 @@
xref: RHEA:14193
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.23
+property_value: skos:exactMatch RHEA:14193
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047564
@@ -299551,6 +310180,9 @@
xref: MetaCyc:3-HYDROXYCYCLOHEXANONE-DEHYDROGENASE-RXN
xref: RHEA:15905
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.26
+property_value: skos:exactMatch RHEA:15905
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047565
@@ -299563,6 +310195,9 @@
xref: MetaCyc:3-HYDROXYPROPIONATE-DEHYDROGENASE-RXN
xref: RHEA:13357
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.59
+property_value: skos:exactMatch RHEA:13357
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047566
@@ -299578,6 +310213,9 @@
xref: MetaCyc:3-KETOVALIDOXYLAMINE-C-N-LYASE-RXN
xref: RHEA:22768
is_a: GO:0016843 ! amine-lyase activity
+property_value: skos:exactMatch EC:4.3.3.1
+property_value: skos:exactMatch RHEA:22768
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047567
@@ -299591,6 +310229,9 @@
xref: MetaCyc:3-METHYLENEOXINDOLE-REDUCTASE-RXN
xref: RHEA:20257
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.17
+property_value: skos:exactMatch RHEA:20257
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047568
@@ -299605,6 +310246,9 @@
xref: MetaCyc:3-OXO-5-BETA-STEROID-4-DEHYDROGENASE-RXN
xref: RHEA:24172
is_a: GO:0033765 ! steroid dehydrogenase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.99.6
+property_value: skos:exactMatch RHEA:24172
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047569
@@ -299620,6 +310264,9 @@
xref: RHEA:12048
xref: UM-BBD_reactionID:r1050
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.6
+property_value: skos:exactMatch RHEA:12048
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047570
@@ -299636,6 +310283,9 @@
xref: MetaCyc:3-OXOADIPATE-ENOL-LACTONASE-RXN
xref: RHEA:10184
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.24
+property_value: skos:exactMatch RHEA:10184
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047571
@@ -299656,6 +310306,9 @@
xref: MetaCyc:3-OXOSTEROID-1-DEHYDROGENASE-RXN
xref: RHEA:13329
is_a: GO:0033765 ! steroid dehydrogenase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.99.4
+property_value: skos:exactMatch RHEA:13329
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047572
@@ -299670,6 +310323,9 @@
xref: MetaCyc:3-PHOSPHOGLYCERATE-PHOSPHATASE-RXN
xref: RHEA:12412
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.38
+property_value: skos:exactMatch RHEA:12412
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047573
@@ -299682,6 +310338,9 @@
xref: RHEA:15897
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0019213 ! deacetylase activity
+property_value: skos:exactMatch EC:3.5.1.63
+property_value: skos:exactMatch RHEA:15897
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047574
@@ -299697,6 +310356,9 @@
xref: RHEA:22928
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0019213 ! deacetylase activity
+property_value: skos:exactMatch EC:3.5.1.51
+property_value: skos:exactMatch RHEA:22928
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047575
@@ -299712,6 +310374,9 @@
xref: MetaCyc:4-CARBOXYMUCONOLACTONE-DECARBOXYLASE-RXN
xref: RHEA:23348
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.44
+property_value: skos:exactMatch RHEA:23348
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047576
@@ -299724,7 +310389,10 @@
xref: KEGG_REACTION:R01307
xref: MetaCyc:4-CHLOROBENZOATE-DEHALOGENASE-RXN
xref: RHEA:23440
-is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds
+is_a: GO:0019120 ! hydrolase activity, acting on halide bonds, in C-halide compounds
+property_value: skos:exactMatch EC:3.8.1.6
+property_value: skos:exactMatch RHEA:23440
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047577
@@ -299738,6 +310406,9 @@
xref: MetaCyc:4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN
xref: RHEA:23948
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.61
+property_value: skos:exactMatch RHEA:23948
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047578
@@ -299751,6 +310422,9 @@
xref: Reactome:R-HSA-6784393 "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)"
xref: RHEA:10480
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.23
+property_value: skos:exactMatch RHEA:10480
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047579
@@ -299764,6 +310438,9 @@
xref: MetaCyc:4-HYDROXYMANDELATE-OXIDASE-RXN
xref: RHEA:15833
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.19
+property_value: skos:exactMatch RHEA:15833
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047580
@@ -299779,6 +310456,9 @@
xref: MetaCyc:4-HYDROXYPROLINE-EPIMERASE-RXN
xref: RHEA:21152
is_a: GO:0047661 ! amino-acid racemase activity
+property_value: skos:exactMatch EC:5.1.1.8
+property_value: skos:exactMatch RHEA:21152
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047581
@@ -299792,6 +310472,9 @@
xref: MetaCyc:4-METHYLENEGLUTAMATE--AMMONIA-LIGASE-RXN
xref: RHEA:13853
is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity
+property_value: skos:exactMatch EC:6.3.1.7
+property_value: skos:exactMatch RHEA:13853
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047582
@@ -299806,6 +310489,9 @@
xref: MetaCyc:4-METHYLENEGLUTAMINASE-RXN
xref: RHEA:14741
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.67
+property_value: skos:exactMatch RHEA:14741
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047583
@@ -299818,6 +310504,9 @@
xref: MetaCyc:4-METHYLOXALOACETATE-ESTERASE-RXN
xref: RHEA:10564
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.44
+property_value: skos:exactMatch RHEA:10564
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047584
@@ -299835,6 +310524,9 @@
xref: MetaCyc:RXN-2463
xref: RHEA:17401
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.83
+property_value: skos:exactMatch RHEA:17401
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047585
@@ -299847,6 +310539,9 @@
xref: MetaCyc:4-PYRIDOXOLACTONASE-RXN
xref: RHEA:14301
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.27
+property_value: skos:exactMatch RHEA:14301
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047586
@@ -299859,6 +310554,9 @@
xref: MetaCyc:5-ACYLPHOSPHOADENOSINE-HYDROLASE-RXN
xref: RHEA:16837
is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
+property_value: skos:exactMatch EC:3.6.1.20
+property_value: skos:exactMatch RHEA:16837
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047587
@@ -299873,6 +310571,9 @@
xref: MetaCyc:5-ALPHA-HYDROXYSTEROID-DEHYDRATASE-RXN
xref: RHEA:22064
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.62
+property_value: skos:exactMatch RHEA:22064
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047588
@@ -299886,6 +310587,9 @@
xref: MetaCyc:5-AMINOPENTANAMIDASE-RXN
xref: RHEA:15677
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.30
+property_value: skos:exactMatch RHEA:15677
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047589
@@ -299901,6 +310605,9 @@
xref: MetaCyc:VAGL-RXN
xref: RHEA:10212
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.48
+property_value: skos:exactMatch RHEA:10212
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047590
@@ -299916,6 +310623,9 @@
xref: RHEA:13497
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.92
+property_value: skos:exactMatch RHEA:13497
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047591
@@ -299930,6 +310640,9 @@
xref: MetaCyc:5-HYDROXYPENTANOATE-COA-TRANSFERASE-RXN
xref: RHEA:23496
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.14
+property_value: skos:exactMatch RHEA:23496
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047592
@@ -299942,7 +310655,10 @@
xref: MetaCyc:5-PYRIDOXATE-DIOXYGENASE-RXN
xref: RHEA:11152
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.241
+property_value: skos:exactMatch RHEA:11152
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047593
@@ -299957,6 +310673,9 @@
xref: RHEA:18485
is_a: GO:0019213 ! deacetylase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.33
+property_value: skos:exactMatch RHEA:18485
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047594
@@ -299971,6 +310690,9 @@
xref: MetaCyc:6-BETA-HYDROXYHYOSCYAMINE-EPOXIDASE-RXN
xref: RHEA:12797
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.20.13
+property_value: skos:exactMatch RHEA:12797
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047595
@@ -299987,6 +310709,9 @@
xref: MetaCyc:6-HYDROXYNICOTINATE-REDUCTASE-RXN
xref: RHEA:17225
is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.3.7.1
+property_value: skos:exactMatch RHEA:17225
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047596
@@ -300002,6 +310727,9 @@
xref: MetaCyc:6-METHYLSALICYLATE-DECARBOXYLASE-RXN
xref: RHEA:23112
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.52
+property_value: skos:exactMatch RHEA:23112
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047597
@@ -300015,6 +310743,9 @@
xref: MetaCyc:6-OXOCINEOLE-DEHYDROGENASE-RXN
xref: RHEA:24324
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.51
+property_value: skos:exactMatch RHEA:24324
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047598
@@ -300031,6 +310762,9 @@
xref: Reactome:R-HSA-6807055 "DHCR7 reduces 7-dehydroCHOL to CHOL"
xref: RHEA:23984
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.21
+property_value: skos:exactMatch RHEA:23984
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047599
@@ -300044,6 +310778,9 @@
xref: MetaCyc:8-OXOCOFORMYCIN-REDUCTASE-RXN
xref: RHEA:23168
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.235
+property_value: skos:exactMatch RHEA:23168
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047600
@@ -300056,6 +310793,9 @@
xref: MetaCyc:ABEQUOSYLTRANSFERASE-RXN
xref: RHEA:34183
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.60
+property_value: skos:exactMatch RHEA:34183
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047601
@@ -300071,6 +310811,9 @@
xref: RHEA:24276
is_a: GO:0016301 ! kinase activity
is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor
+property_value: skos:exactMatch EC:2.7.2.12
+property_value: skos:exactMatch RHEA:24276
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047602
@@ -300085,6 +310828,9 @@
xref: MetaCyc:ACETOACETATE-DECARBOXYLASE-RXN
xref: RHEA:19729
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.4
+property_value: skos:exactMatch RHEA:19729
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047603
@@ -300099,6 +310845,9 @@
xref: MetaCyc:ACETOACETYL-COA-HYDROLASE-RXN
xref: RHEA:15673
is_a: GO:0016289 ! acyl-CoA hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.11
+property_value: skos:exactMatch RHEA:15673
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047604
@@ -300111,6 +310860,9 @@
xref: MetaCyc:ACETOIN-RACEMASE-RXN
xref: RHEA:12092
is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives
+property_value: skos:exactMatch EC:5.1.2.4
+property_value: skos:exactMatch RHEA:12092
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047605
@@ -300124,6 +310876,9 @@
xref: MetaCyc:ACETOLACTATE-DECARBOXYLASE-RXN
xref: RHEA:21580
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.5
+property_value: skos:exactMatch RHEA:21580
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047606
@@ -300137,8 +310892,10 @@
synonym: "oxynitrilase activity" RELATED []
xref: EC:4.1.2.47
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.47
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16166" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047608
@@ -300150,6 +310907,9 @@
xref: MetaCyc:ACETYLINDOXYL-OXIDASE-RXN
xref: RHEA:16941
is_a: GO:0016663 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.7.3.2
+property_value: skos:exactMatch RHEA:16941
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047609
@@ -300163,6 +310923,9 @@
xref: RHEA:23412
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0019213 ! deacetylase activity
+property_value: skos:exactMatch EC:3.5.1.62
+property_value: skos:exactMatch RHEA:23412
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047610
@@ -300179,6 +310942,9 @@
xref: RHEA:11752
is_a: GO:0019213 ! deacetylase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.55
+property_value: skos:exactMatch RHEA:11752
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047611
@@ -300201,6 +310967,9 @@
xref: RHEA:23928
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0019213 ! deacetylase activity
+property_value: skos:exactMatch EC:3.5.1.48
+property_value: skos:exactMatch RHEA:23928
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047612
@@ -300215,6 +310984,9 @@
xref: MetaCyc:ACID--COA-LIGASE-GDP-FORMING-RXN
xref: RHEA:10968
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.10
+property_value: skos:exactMatch RHEA:10968
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047613
@@ -300230,6 +311002,9 @@
xref: MetaCyc:ACONITATE-DECARBOXYLASE-RXN
xref: RHEA:15253
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.6
+property_value: skos:exactMatch RHEA:15253
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047614
@@ -300244,6 +311019,9 @@
xref: MetaCyc:ACONITATE-DELTA-ISOMERASE-RXN
xref: RHEA:17265
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.7
+property_value: skos:exactMatch RHEA:17265
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047615
@@ -300254,6 +311032,8 @@
xref: EC:3.1.1.39
xref: MetaCyc:ACTINOMYCIN-LACTONASE-RXN
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.39
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047616
@@ -300269,6 +311049,9 @@
xref: MetaCyc:ACYL-COA-DEHYDROGENASE-NADP+-RXN
xref: RHEA:22460
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.8
+property_value: skos:exactMatch RHEA:22460
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047617
@@ -300295,7 +311078,10 @@
xref: Reactome:R-HSA-5690066 "ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA"
xref: RHEA:16781
is_a: GO:0016289 ! acyl-CoA hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.20
+property_value: skos:exactMatch RHEA:16781
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26441" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047618
@@ -300310,6 +311096,9 @@
xref: MetaCyc:ACYLAGMATINE-AMIDASE-RXN
xref: RHEA:15065
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.40
+property_value: skos:exactMatch RHEA:15065
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047619
@@ -300328,6 +311117,9 @@
xref: MetaCyc:ACYLCARNITINE-HYDROLASE-RXN
xref: RHEA:17101
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.28
+property_value: skos:exactMatch RHEA:17101
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047620
@@ -300347,6 +311139,9 @@
xref: RHEA:19293
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.94
+property_value: skos:exactMatch RHEA:19293
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047621
@@ -300358,7 +311153,10 @@
xref: MetaCyc:ACYLPYRUVATE-HYDROLASE-RXN
xref: RHEA:19009
xref: UM-BBD_reactionID:r1401
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.5
+property_value: skos:exactMatch RHEA:19009
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047622
@@ -300374,6 +311172,9 @@
xref: MetaCyc:ADENOSINE-NUCLEOSIDASE-RXN
xref: RHEA:18669
is_a: GO:0008477 ! purine nucleosidase activity
+property_value: skos:exactMatch EC:3.2.2.7
+property_value: skos:exactMatch RHEA:18669
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047623
@@ -300387,17 +311188,22 @@
xref: EC:3.5.4.17
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.17
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047624
name: adenosine-tetraphosphatase activity
namespace: molecular_function
-def: "Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = ATP + phosphate." [EC:3.6.1.14, MetaCyc:ADENOSINE-TETRAPHOSPHATASE-RXN]
+def: "Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = phosphate + ATP + H+." [RHEA:24500]
synonym: "adenosine-tetraphosphate phosphohydrolase activity" RELATED [EC:3.6.1.14]
xref: EC:3.6.1.14
xref: MetaCyc:ADENOSINE-TETRAPHOSPHATASE-RXN
xref: RHEA:24500
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.14
+property_value: skos:exactMatch RHEA:24500
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047625
@@ -300412,7 +311218,10 @@
xref: MetaCyc:ADENOSYLMETHIONINE-CYCLOTRANSFERASE-RXN
xref: RHEA:21932
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.42
+property_value: skos:exactMatch RHEA:21932
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047626
@@ -300438,6 +311247,9 @@
xref: MetaCyc:ADENYLYLSULFATASE-RXN
xref: RHEA:17041
is_a: GO:0016819 ! hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides
+property_value: skos:exactMatch EC:3.6.2.1
+property_value: skos:exactMatch RHEA:17041
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047628
@@ -300452,6 +311264,9 @@
xref: RHEA:13413
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.118
+property_value: skos:exactMatch RHEA:13413
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047629
@@ -300465,6 +311280,9 @@
xref: MetaCyc:ADP-DEAMINASE-RXN
xref: RHEA:12741
is_a: GO:0047623 ! adenosine-phosphate deaminase activity
+property_value: skos:exactMatch EC:3.5.4.7
+property_value: skos:exactMatch RHEA:12741
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047630
@@ -300479,6 +311297,9 @@
xref: MetaCyc:ADP-PHOSPHOGLYCERATE-PHOSPHATASE-RXN
xref: RHEA:15861
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.28
+property_value: skos:exactMatch RHEA:15861
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047631
@@ -300486,8 +311307,6 @@
namespace: molecular_function
def: "Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate." [EC:3.6.1.13]
synonym: "adenosine diphosphoribose pyrophosphatase activity" EXACT []
-synonym: "ADP-ribose phosphohydrolase activity" EXACT []
-synonym: "ADP-ribose pyrophosphatase activity" EXACT []
synonym: "ADP-ribose ribophosphohydrolase activity" RELATED [EC:3.6.1.13]
synonym: "ADPR-PPase activity" EXACT []
synonym: "ADPribose diphosphatase activity" RELATED [EC:3.6.1.13]
@@ -300499,6 +311318,9 @@
xref: Reactome:R-HSA-5696049 "ADPRM hydrolyses ADP-ribose to R5P and AMP"
xref: RHEA:10412
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.13
+property_value: skos:exactMatch RHEA:10412
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047632
@@ -300511,6 +311333,9 @@
xref: MetaCyc:AGMATINE-DEIMINASE-RXN
xref: RHEA:18037
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.12
+property_value: skos:exactMatch RHEA:18037
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047633
@@ -300526,6 +311351,9 @@
xref: RHEA:15953
is_a: GO:0016301 ! kinase activity
is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor
+property_value: skos:exactMatch EC:2.7.3.10
+property_value: skos:exactMatch RHEA:15953
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047634
@@ -300541,6 +311369,9 @@
xref: MetaCyc:AGMATINE-N4-COUMAROYLTRANSFERASE-RXN
xref: RHEA:13405
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.64
+property_value: skos:exactMatch RHEA:13405
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047635
@@ -300558,6 +311389,9 @@
xref: MetaCyc:ALANINE--OXO-ACID-AMINOTRANSFERASE-RXN
xref: RHEA:19953
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.12
+property_value: skos:exactMatch RHEA:19953
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047636
@@ -300576,6 +311410,9 @@
xref: MetaCyc:ALANOPINE-DEHYDROGENASE-RXN
xref: RHEA:17589
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.17
+property_value: skos:exactMatch RHEA:17589
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047637
@@ -300587,7 +311424,10 @@
xref: MetaCyc:ALANYLPHOSPHATIDYLGLYCEROL-SYNTHASE-RXN
xref: RHEA:20489
is_a: GO:0016755 ! aminoacyltransferase activity
+property_value: skos:exactMatch EC:2.3.2.11
+property_value: skos:exactMatch RHEA:20489
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047638
@@ -300602,6 +311442,9 @@
xref: MetaCyc:ALBENDAZOLE-MONOOXYGENASE-RXN
xref: RHEA:10796
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.32
+property_value: skos:exactMatch RHEA:10796
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047639
@@ -300613,8 +311456,13 @@
synonym: "ethanol oxidase activity" RELATED [EC:1.1.3.13]
xref: EC:1.1.3.13
xref: MetaCyc:ALCOHOL-OXIDASE-RXN
+xref: MetaCyc:METHANOL-OXIDASE-RXN
xref: RHEA:19829
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.13
+property_value: skos:exactMatch MetaCyc:ALCOHOL-OXIDASE-RXN
+property_value: skos:exactMatch RHEA:19829
+property_value: skos:narrowMatch MetaCyc:METHANOL-OXIDASE-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -300629,6 +311477,9 @@
xref: MetaCyc:ALDOSE-1-DEHYDROGENASE-RXN
xref: RHEA:15917
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.121
+property_value: skos:exactMatch RHEA:15917
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047641
@@ -300648,6 +311499,9 @@
xref: MetaCyc:ALDOSE-6-PHOSPHATE-REDUCTASE-NADPH-RXN
xref: RHEA:20037
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.200
+property_value: skos:exactMatch RHEA:20037
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047642
@@ -300659,6 +311513,8 @@
xref: EC:2.4.1.162
xref: MetaCyc:ALDOSE-BETA-FRUCTOSYLTRANSFERASE-RXN
is_a: GO:0050738 ! fructosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.162
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047643
@@ -300671,6 +311527,9 @@
xref: MetaCyc:ALGINATE-SYNTHASE-RXN
xref: RHEA:46876
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.33
+property_value: skos:exactMatch RHEA:46876
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047644
@@ -300686,6 +311545,9 @@
xref: MetaCyc:ALIZARIN-2-BETA-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:20677
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.103
+property_value: skos:exactMatch RHEA:20677
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047645
@@ -300699,6 +311561,9 @@
xref: MetaCyc:ALKAN-1-OL-DEHYDROGENASE-ACCEPTOR-RXN
xref: RHEA:14685
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.20
+property_value: skos:exactMatch RHEA:14685
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047646
@@ -300713,6 +311578,9 @@
xref: MetaCyc:ALKANAL-MONOOXYGENASE-FMN-LINKED-RXN
xref: RHEA:17181
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.3
+property_value: skos:exactMatch RHEA:17181
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047647
@@ -300727,6 +311595,9 @@
xref: MetaCyc:ALKYLACETYLGLYCEROPHOSPHATASE-RXN
xref: RHEA:18221
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.59
+property_value: skos:exactMatch RHEA:18221
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047648
@@ -300739,6 +311610,9 @@
xref: MetaCyc:ALKYLAMIDASE-RXN
xref: RHEA:20081
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.39
+property_value: skos:exactMatch RHEA:20081
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047649
@@ -300756,6 +311630,9 @@
xref: RHEA:16937
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.93
+property_value: skos:exactMatch RHEA:16937
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047650
@@ -300771,6 +311648,9 @@
xref: RHEA:23088
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.84
+property_value: skos:exactMatch RHEA:23088
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047651
@@ -300782,7 +311662,9 @@
synonym: "halogenase activity" RELATED []
xref: KEGG_REACTION:R03523
xref: RHEA:13765
-is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds
+is_a: GO:0019120 ! hydrolase activity, acting on halide bonds, in C-halide compounds
+property_value: skos:exactMatch RHEA:13765
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047652
@@ -300795,6 +311677,9 @@
xref: MetaCyc:ALLANTOATE-DEIMINASE-RXN
xref: RHEA:27485
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.9
+property_value: skos:exactMatch RHEA:27485
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047653
@@ -300806,6 +311691,9 @@
xref: MetaCyc:ALLANTOIN-RACEMASE-RXN
xref: RHEA:10804
is_a: GO:0016854 ! racemase and epimerase activity
+property_value: skos:exactMatch EC:5.1.99.3
+property_value: skos:exactMatch RHEA:10804
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047654
@@ -300824,6 +311712,9 @@
xref: MetaCyc:ALLIIN-LYASE-RXN
xref: RHEA:20141
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.4
+property_value: skos:exactMatch RHEA:20141
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047655
@@ -300836,6 +311727,9 @@
xref: MetaCyc:ALLYL-ALCOHOL-DEHYDROGENASE-RXN
xref: RHEA:12168
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.54
+property_value: skos:exactMatch RHEA:12168
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047656
@@ -300849,6 +311743,9 @@
xref: MetaCyc:ALPHAALPHA-TREHALOSE-PHOSPHORYLASE-RXN
xref: RHEA:23512
is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity
+property_value: skos:exactMatch EC:2.4.1.64
+property_value: skos:exactMatch RHEA:23512
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047657
@@ -300866,6 +311763,9 @@
xref: RHEA:19749
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.183
+property_value: skos:exactMatch RHEA:19749
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047658
@@ -300881,6 +311781,9 @@
xref: Reactome:R-HSA-6784959 "BPHL hydrolyses VACV to ACV"
xref: RHEA:17241
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.43
+property_value: skos:exactMatch RHEA:17241
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047659
@@ -300892,6 +311795,8 @@
xref: EC:1.3.1.47
xref: MetaCyc:ALPHA-SANTONIN-12-REDUCTASE-RXN
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.47
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047660
@@ -300905,6 +311810,9 @@
xref: MetaCyc:AMIDINOASPARTASE-RXN
xref: RHEA:14849
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.14
+property_value: skos:exactMatch RHEA:14849
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047661
@@ -300916,6 +311824,9 @@
xref: MetaCyc:AMINO-ACID-RACEMASE-RXN
xref: RHEA:18317
is_a: GO:0016855 ! racemase and epimerase activity, acting on amino acids and derivatives
+property_value: skos:exactMatch EC:5.1.1.10
+property_value: skos:exactMatch RHEA:18317
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047662
@@ -300928,6 +311839,9 @@
xref: MetaCyc:AMINOBENZOATE-DECARBOXYLASE-RXN
xref: RHEA:24200
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.24
+property_value: skos:exactMatch RHEA:24200
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047663
@@ -300946,6 +311860,9 @@
xref: MetaCyc:AMINOGLYCOSIDE-N6-ACETYLTRANSFERASE-RXN
xref: RHEA:16449
is_a: GO:0034069 ! aminoglycoside N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.82
+property_value: skos:exactMatch RHEA:16449
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047664
@@ -300958,6 +311875,9 @@
xref: MetaCyc:R13-RXN
xref: RHEA:22348
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
+property_value: skos:exactMatch EC:3.5.4.8
+property_value: skos:exactMatch RHEA:22348
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047665
@@ -300987,6 +311907,9 @@
xref: MetaCyc:AMINOLEVULINATE-AMINOTRANSFERASE-RXN
xref: RHEA:12480
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.43
+property_value: skos:exactMatch RHEA:12480
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047666
@@ -301002,6 +311925,9 @@
xref: RHEA:11024
is_a: GO:0016301 ! kinase activity
is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor
+property_value: skos:exactMatch EC:2.7.3.8
+property_value: skos:exactMatch RHEA:11024
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047667
@@ -301020,6 +311946,9 @@
xref: RHEA:14913
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.114
+property_value: skos:exactMatch RHEA:14913
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047668
@@ -301038,6 +311967,9 @@
xref: MetaCyc:AMYGDALIN-BETA-GLUCOSIDASE-RXN
xref: RHEA:14177
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.117
+property_value: skos:exactMatch RHEA:14177
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047669
@@ -301051,6 +311983,9 @@
xref: MetaCyc:AMYLOSUCRASE-RXN
xref: RHEA:24572
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.4
+property_value: skos:exactMatch RHEA:24572
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047670
@@ -301065,6 +312000,9 @@
xref: MetaCyc:ANHYDROTETRACYCLINE-MONOOXYGENASE-RXN
xref: RHEA:11976
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.38
+property_value: skos:exactMatch RHEA:11976
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047671
@@ -301078,7 +312016,10 @@
xref: MetaCyc:RXN-13989
xref: RHEA:35091
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.40
+property_value: skos:exactMatch RHEA:35091
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25980" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047672
@@ -301091,6 +312032,9 @@
xref: MetaCyc:ANTHRANILATE-N-BENZOYLTRANSFERASE-RXN
xref: RHEA:21600
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.144
+property_value: skos:exactMatch RHEA:21600
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047673
@@ -301103,6 +312047,9 @@
xref: MetaCyc:ANTHRANILATE-N-MALONYLTRANSFERASE-RXN
xref: RHEA:17557
is_a: GO:0050735 ! N-malonyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.113
+property_value: skos:exactMatch RHEA:17557
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047674
@@ -301117,6 +312064,9 @@
xref: MetaCyc:APIOSE-1-REDUCTASE-RXN
xref: RHEA:15301
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.114
+property_value: skos:exactMatch RHEA:15301
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047675
@@ -301130,6 +312080,9 @@
xref: MetaCyc:ARABINONATE-DEHYDRATASE-RXN
xref: RHEA:21836
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.5
+property_value: skos:exactMatch RHEA:21836
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047676
@@ -301143,6 +312096,9 @@
xref: MetaCyc:ARACHIDONATE--COA-LIGASE-RXN
xref: RHEA:19713
is_a: GO:0004467 ! long-chain fatty acid-CoA ligase activity
+property_value: skos:exactMatch EC:6.2.1.15
+property_value: skos:exactMatch RHEA:19713
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047677
@@ -301159,6 +312115,9 @@
xref: MetaCyc:ARACHIDONATE-8-LIPOXYGENASE-RXN
xref: RHEA:14985
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.40
+property_value: skos:exactMatch RHEA:14985
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047678
@@ -301174,6 +312133,9 @@
xref: MetaCyc:ARGININE-2-MONOOXYGENASE-RXN
xref: RHEA:10548
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
+property_value: skos:exactMatch EC:1.13.12.1
+property_value: skos:exactMatch RHEA:10548
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047679
@@ -301184,6 +312146,9 @@
xref: MetaCyc:ARGININE-RACEMASE-RXN
xref: RHEA:18069
is_a: GO:0047661 ! amino-acid racemase activity
+property_value: skos:exactMatch EC:5.1.1.9
+property_value: skos:exactMatch RHEA:18069
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047680
@@ -301200,6 +312165,9 @@
xref: MetaCyc:ARYL-ACYLAMIDASE-RXN
xref: RHEA:20297
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.13
+property_value: skos:exactMatch RHEA:20297
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047681
@@ -301213,6 +312181,9 @@
xref: MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-NADP+-RXN
xref: RHEA:17761
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.91
+property_value: skos:exactMatch RHEA:17761
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047682
@@ -301227,6 +312198,9 @@
xref: MetaCyc:ARYL-ALCOHOL-OXIDASE-RXN
xref: RHEA:17541
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.7
+property_value: skos:exactMatch RHEA:17541
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047683
@@ -301239,6 +312213,9 @@
xref: MetaCyc:1.2.1.30-RXN
xref: RHEA:19229
is_a: GO:0033721 ! aldehyde dehydrogenase (NADP+) activity
+property_value: skos:exactMatch EC:1.2.1.30
+property_value: skos:exactMatch RHEA:19229
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047684
@@ -301252,6 +312229,8 @@
xref: EC:2.4.1.71
xref: MetaCyc:ARYLAMINE-GLUCOSYLTRANSFERASE-RXN
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.71
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047685
@@ -301266,6 +312245,9 @@
xref: MetaCyc:ARYLAMINE-SULFOTRANSFERASE-RXN
xref: RHEA:24136
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.3
+property_value: skos:exactMatch RHEA:24136
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047686
@@ -301281,6 +312263,9 @@
xref: MetaCyc:ARYLSULFATE-SULFOTRANSFERASE-RXN
xref: RHEA:51072
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.22
+property_value: skos:exactMatch RHEA:51072
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047687
@@ -301313,6 +312298,9 @@
xref: MetaCyc:ASPARTATE-4-DECARBOXYLASE-RXN
xref: RHEA:12621
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.12
+property_value: skos:exactMatch RHEA:12621
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047689
@@ -301325,6 +312313,9 @@
xref: MetaCyc:ASPARTATE-RACEMASE-RXN
xref: RHEA:14973
is_a: GO:0047661 ! amino-acid racemase activity
+property_value: skos:exactMatch EC:5.1.1.13
+property_value: skos:exactMatch RHEA:14973
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047690
@@ -301350,6 +312341,9 @@
xref: MetaCyc:ASPULVINONE-DIMETHYLALLYLTRANSFERASE-RXN
xref: RHEA:13809
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.35
+property_value: skos:exactMatch RHEA:13809
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047692
@@ -301362,6 +312356,9 @@
xref: MetaCyc:ATP-DEAMINASE-RXN
xref: RHEA:13037
is_a: GO:0047623 ! adenosine-phosphate deaminase activity
+property_value: skos:exactMatch EC:3.5.4.18
+property_value: skos:exactMatch RHEA:13037
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047693
@@ -301376,6 +312373,9 @@
xref: MetaCyc:ATP-PYROPHOSPHATASE-RXN
xref: RHEA:14245
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:exactMatch EC:3.6.1.8
+property_value: skos:exactMatch RHEA:14245
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047694
@@ -301387,6 +312387,9 @@
xref: MetaCyc:BARBITURASE-RXN
xref: RHEA:18653
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.1
+property_value: skos:exactMatch RHEA:18653
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047695
@@ -301403,6 +312406,9 @@
xref: MetaCyc:BENZOIN-ALDOLASE-RXN
xref: RHEA:21460
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.38
+property_value: skos:exactMatch RHEA:21460
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047696
@@ -301436,6 +312442,9 @@
xref: Reactome:R-HSA-8866268 "ADBRK1,2 phosphorylate AVPR2"
xref: RHEA:19429
is_a: GO:0004672 ! protein kinase activity
+property_value: skos:exactMatch EC:2.7.11.15
+property_value: skos:exactMatch RHEA:19429
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047697
@@ -301449,6 +312458,9 @@
xref: MetaCyc:BETA-ALANOPINE-DEHYDROGENASE-RXN
xref: RHEA:21684
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.26
+property_value: skos:exactMatch RHEA:21684
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047698
@@ -301462,6 +312474,9 @@
xref: MetaCyc:BETA-ALANYL-COA-AMMONIA-LYASE-RXN
xref: RHEA:12416
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.6
+property_value: skos:exactMatch RHEA:12416
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047699
@@ -301475,7 +312490,10 @@
xref: KEGG_REACTION:R03781
xref: MetaCyc:BETA-DIKETONE-HYDROLASE-RXN
xref: RHEA:11908
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.7
+property_value: skos:exactMatch RHEA:11908
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047700
@@ -301490,6 +312508,9 @@
xref: RHEA:21944
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.85
+property_value: skos:exactMatch RHEA:21944
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047701
@@ -301502,6 +312523,8 @@
xref: EC:3.2.1.88
xref: MetaCyc:BETA-L-ARABINOSIDASE-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.88
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047702
@@ -301526,6 +312549,9 @@
xref: MetaCyc:BETA-NITROACRYLATE-REDUCTASE-RXN
xref: RHEA:23892
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.16
+property_value: skos:exactMatch RHEA:23892
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047704
@@ -301544,6 +312570,9 @@
xref: MetaCyc:BILE-SALT-SULFOTRANSFERASE-RXN
xref: RHEA:14013
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.14
+property_value: skos:exactMatch RHEA:14013
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047705
@@ -301557,6 +312586,9 @@
xref: MetaCyc:BILIRUBIN-OXIDASE-RXN
xref: RHEA:20980
is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.3.3.5
+property_value: skos:exactMatch RHEA:20980
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047706
@@ -301569,6 +312601,9 @@
xref: MetaCyc:BIOCHANIN-A-REDUCTASE-RXN
xref: RHEA:12817
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.46
+property_value: skos:exactMatch RHEA:12817
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047707
@@ -301584,6 +312619,9 @@
xref: RHEA:19681
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.11
+property_value: skos:exactMatch RHEA:19681
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047708
@@ -301600,6 +312638,9 @@
xref: Reactome:R-HSA-4225086 "Defective mitochondrial BTD does not hydrolyse BCTN"
xref: RHEA:13081
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.12
+property_value: skos:exactMatch RHEA:13081
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047709
@@ -301613,6 +312654,9 @@
xref: MetaCyc:BIS2-ETHYLHEXYLPHTHALATE-ESTERASE-RXN
xref: RHEA:15529
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.60
+property_value: skos:exactMatch RHEA:15529
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047710
@@ -301634,7 +312678,10 @@
xref: MetaCyc:BIS5-ADENOSYL-TRIPHOSPHATASE-RXN
xref: RHEA:13893
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.29
+property_value: skos:exactMatch RHEA:13893
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047711
@@ -301647,6 +312694,9 @@
xref: RHEA:10148
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.23
+property_value: skos:exactMatch RHEA:10148
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047712
@@ -301663,6 +312713,9 @@
xref: RHEA:22760
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
is_a: GO:0045289 ! luciferin monooxygenase activity
+property_value: skos:exactMatch EC:1.13.12.6
+property_value: skos:exactMatch RHEA:22760
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047713
@@ -301675,6 +312728,9 @@
xref: RHEA:20685
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
is_a: GO:0031320 ! hexitol dehydrogenase activity
+property_value: skos:exactMatch EC:1.1.1.16
+property_value: skos:exactMatch RHEA:20685
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047714
@@ -301690,6 +312746,9 @@
xref: RHEA:13189
is_a: GO:0016298 ! lipase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.26
+property_value: skos:exactMatch MetaCyc:GALACTOLIPASE-RXN
+property_value: skos:exactMatch RHEA:13189
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28339" xsd:anyURI
[Term]
@@ -301704,6 +312763,9 @@
xref: RHEA:24008
is_a: GO:0016301 ! kinase activity
is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor
+property_value: skos:exactMatch EC:2.7.3.6
+property_value: skos:exactMatch RHEA:24008
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047716
@@ -301718,6 +312780,9 @@
xref: MetaCyc:IMIDAZOLE-N-ACETYLTRANSFERASE-RXN
xref: RHEA:15813
is_a: GO:0008080 ! N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.2
+property_value: skos:exactMatch RHEA:15813
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047717
@@ -301733,6 +312798,9 @@
xref: MetaCyc:IMIDAZOLEACETATE-4-MONOOXYGENASE-RXN
xref: RHEA:19425
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.5
+property_value: skos:exactMatch RHEA:19425
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047718
@@ -301743,6 +312811,8 @@
xref: EC:1.1.1.112
xref: MetaCyc:INDANOL-DEHYDROGENASE-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.112
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047719
@@ -301759,6 +312829,9 @@
xref: MetaCyc:INDOLE-23-DIOXYGENASE-RXN
xref: RHEA:11212
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.17
+property_value: skos:exactMatch RHEA:11212
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047720
@@ -301775,7 +312848,10 @@
xref: MetaCyc:RXN-19838
xref: RHEA:23156
is_a: GO:0141122 ! nitrogen-oxygen lyase activity
+property_value: skos:exactMatch EC:4.8.1.3
+property_value: skos:exactMatch RHEA:23156
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24927" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047721
@@ -301792,6 +312868,9 @@
xref: MetaCyc:INDOLEACETATE--LYSINE-LIGASE-RXN
xref: RHEA:14857
is_a: GO:0010279 ! indole-3-acetic acid amido synthetase activity
+property_value: skos:exactMatch EC:6.3.2.20
+property_value: skos:exactMatch RHEA:14857
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047722
@@ -301805,6 +312884,8 @@
xref: MetaCyc:INDOLELACTATE-DEHYDROGENASE-RXN
xref: RHEA:20133
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.1.1.110
+property_value: skos:exactMatch RHEA:20133
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
@@ -301819,6 +312900,9 @@
xref: MetaCyc:INOSINATE-NUCLEOSIDASE-RXN
xref: RHEA:20469
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.2.12
+property_value: skos:exactMatch RHEA:20469
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047724
@@ -301832,6 +312916,9 @@
xref: MetaCyc:INOSINE-NUCLEOSIDASE-RXN
xref: RHEA:16657
is_a: GO:0008477 ! purine nucleosidase activity
+property_value: skos:exactMatch EC:3.2.2.2
+property_value: skos:exactMatch RHEA:16657
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047725
@@ -301845,6 +312932,9 @@
xref: MetaCyc:RXN-15518
xref: RHEA:15745
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.9
+property_value: skos:exactMatch RHEA:15745
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047726
@@ -301857,6 +312947,9 @@
xref: MetaCyc:IRON--CYTOCHROME-C-REDUCTASE-RXN
xref: RHEA:15617
is_a: GO:0016675 ! oxidoreductase activity, acting on a heme group of donors
+property_value: skos:exactMatch EC:1.9.98.1
+property_value: skos:exactMatch RHEA:15617
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047727
@@ -301871,6 +312964,9 @@
xref: MetaCyc:ISOBUTYRYL-COA-MUTASE-RXN
xref: RHEA:13141
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.13
+property_value: skos:exactMatch RHEA:13141
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047728
@@ -301883,6 +312979,9 @@
xref: MetaCyc:CARNITINE-3-DEHYDROGENASE-RXN
xref: RHEA:19265
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.108
+property_value: skos:exactMatch RHEA:19265
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047729
@@ -301896,6 +312995,9 @@
xref: MetaCyc:CARNITINE-DECARBOXYLASE-RXN
xref: RHEA:21576
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.42
+property_value: skos:exactMatch RHEA:21576
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047730
@@ -301909,9 +313011,21 @@
synonym: "L-histidine:beta-alanine ligase (AMP-forming)" RELATED [EC:6.3.2.11]
xref: EC:6.3.2.11
xref: MetaCyc:CARNOSINE-SYNTHASE-RXN
+xref: MetaCyc:RXN-11222
xref: Reactome:R-HSA-6786245 "CARNS1 transforms ATP, L-His, b-Ala to CARN"
xref: RHEA:19297
+xref: RHEA:59568
+xref: RHEA:59584
+xref: RHEA:59588
+xref: RHEA:59592
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.11
+property_value: skos:exactMatch RHEA:19297
+property_value: skos:narrowMatch MetaCyc:RXN-11222
+property_value: skos:narrowMatch RHEA:59568
+property_value: skos:narrowMatch RHEA:59584
+property_value: skos:narrowMatch RHEA:59588
+property_value: skos:narrowMatch RHEA:59592
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29764" xsd:anyURI
[Term]
@@ -301924,6 +313038,9 @@
xref: MetaCyc:CATECHOL-OXIDASE-DIMERIZING-RXN
xref: RHEA:12809
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.14
+property_value: skos:exactMatch RHEA:12809
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047732
@@ -301944,6 +313061,9 @@
xref: MetaCyc:RXN-9160
xref: RHEA:21656
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.10
+property_value: skos:exactMatch RHEA:21656
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047733
@@ -301960,6 +313080,9 @@
xref: MetaCyc:CDP-GLUCOSE-46-DEHYDRATASE-RXN
xref: RHEA:17153
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.45
+property_value: skos:exactMatch RHEA:17153
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047734
@@ -301977,6 +313100,9 @@
xref: MetaCyc:CDP-GLYCEROL-PYROPHOSPHATASE-RXN
xref: RHEA:21692
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.16
+property_value: skos:exactMatch RHEA:21692
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047735
@@ -301999,6 +313125,9 @@
xref: MetaCyc:CELLOBIOSE-DEHYDROGENASE-ACCEPTOR-RXN
xref: RHEA:23484
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.18
+property_value: skos:exactMatch RHEA:23484
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047736
@@ -302010,6 +313139,9 @@
xref: MetaCyc:CELLOBIOSE-EPIMERASE-RXN
xref: RHEA:23384
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.11
+property_value: skos:exactMatch RHEA:23384
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047738
@@ -302021,6 +313153,8 @@
xref: MetaCyc:CELLOBIOSE-PHOSPHORYLASE-RXN
xref: RHEA:19493
is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity
+property_value: skos:exactMatch EC:2.4.1.20
+property_value: skos:exactMatch RHEA:19493
[Term]
id: GO:0047739
@@ -302040,6 +313174,9 @@
xref: RHEA:22596
is_a: GO:0019213 ! deacetylase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.41
+property_value: skos:exactMatch RHEA:22596
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047740
@@ -302054,6 +313191,9 @@
xref: MetaCyc:CEPHALOSPORIN-C-TRANSAMINASE-RXN
xref: RHEA:14553
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.74
+property_value: skos:exactMatch RHEA:14553
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047741
@@ -302066,6 +313206,9 @@
xref: MetaCyc:CETRAXATE-BENZYLESTERASE-RXN
xref: RHEA:23460
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.70
+property_value: skos:exactMatch RHEA:23460
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047742
@@ -302077,6 +313220,9 @@
xref: MetaCyc:CHENODEOXYCHOLOYLTAURINE-HYDROLASE-RXN
xref: RHEA:16309
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.74
+property_value: skos:exactMatch RHEA:16309
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047743
@@ -302090,6 +313236,9 @@
xref: MetaCyc:CHLORDECONE-REDUCTASE-RXN
xref: RHEA:14401
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.225
+property_value: skos:exactMatch RHEA:14401
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047744
@@ -302102,6 +313251,9 @@
xref: MetaCyc:CHLORIDAZON-CATECHOL-DIOXYGENASE-RXN
xref: RHEA:20449
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.36
+property_value: skos:exactMatch RHEA:20449
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047745
@@ -302115,6 +313267,9 @@
xref: MetaCyc:CHLOROGENATE-HYDROLASE-RXN
xref: RHEA:20689
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.42
+property_value: skos:exactMatch RHEA:20689
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047746
@@ -302126,6 +313281,8 @@
xref: MetaCyc:CHLOROPHYLLASE-RXN
xref: RHEA:19605
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.14
+property_value: skos:exactMatch RHEA:19605
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -302159,8 +313316,20 @@
synonym: "trihydroxycoprostanoyl-CoA synthetase activity" RELATED [EC:6.2.1.7]
xref: EC:6.2.1.7
xref: MetaCyc:CHOLATE--COA-LIGASE-RXN
+xref: RHEA:22976
+xref: RHEA:23532
+xref: RHEA:43764
+xref: RHEA:47128
+xref: RHEA:47136
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.7
+property_value: skos:narrowMatch RHEA:22976
+property_value: skos:narrowMatch RHEA:23532
+property_value: skos:narrowMatch RHEA:43764
+property_value: skos:narrowMatch RHEA:47128
+property_value: skos:narrowMatch RHEA:47136
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047748
@@ -302175,6 +313344,9 @@
xref: MetaCyc:RXN-13690
xref: RHEA:34631
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.15.15
+property_value: skos:exactMatch MetaCyc:RXN-13690
+property_value: skos:exactMatch RHEA:34631
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
@@ -302201,6 +313373,9 @@
xref: MetaCyc:RXN66-25
xref: RHEA:15281
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.5
+property_value: skos:exactMatch RHEA:15281
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047751
@@ -302221,9 +313396,18 @@
xref: EC:1.3.1.22
xref: KEGG_REACTION:R02610
xref: MetaCyc:1.3.99.5-RXN
+xref: MetaCyc:CHOLESTENONE-5-ALPHA-REDUCTASE-RXN
+xref: MetaCyc:RXN-4229
+xref: MetaCyc:RXN-711
xref: RHEA:54384
is_a: GO:0003865 ! 3-oxo-5-alpha-steroid 4-dehydrogenase activity
is_a: GO:0035671 ! enone reductase activity
+property_value: skos:exactMatch EC:1.3.1.22
+property_value: skos:exactMatch MetaCyc:1.3.99.5-RXN
+property_value: skos:exactMatch RHEA:54384
+property_value: skos:narrowMatch MetaCyc:CHOLESTENONE-5-ALPHA-REDUCTASE-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-4229
+property_value: skos:narrowMatch MetaCyc:RXN-711
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25314" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
@@ -302239,6 +313423,9 @@
xref: MetaCyc:CHOLINE-SULFATASE-RXN
xref: RHEA:20820
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.6
+property_value: skos:exactMatch RHEA:20820
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047754
@@ -302253,6 +313440,9 @@
xref: MetaCyc:CHOLINE-SULFOTRANSFERASE-RXN
xref: RHEA:21984
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.6
+property_value: skos:exactMatch RHEA:21984
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047755
@@ -302265,6 +313455,9 @@
xref: MetaCyc:ISOCITRATE-EPIMERASE-RXN
xref: RHEA:10820
is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives
+property_value: skos:exactMatch EC:5.1.2.6
+property_value: skos:exactMatch RHEA:10820
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047756
@@ -302275,9 +313468,12 @@
synonym: "chondroitin 4-sulphotransferase activity" EXACT []
xref: EC:2.8.2.5
xref: MetaCyc:CHONDROITIN-4-SULFOTRANSFERASE-RXN
-xref: Reactome:R-HSA-1971483 "CHST11,12,13,9 transfer sulfate to (4-)GalNAc"
+xref: Reactome:R-HSA-1971483 "Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13"
xref: RHEA:16101
is_a: GO:0034481 ! chondroitin sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.5
+property_value: skos:exactMatch RHEA:16101
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047757
@@ -302291,9 +313487,12 @@
synonym: "urunosyl C-5 epimerase activity" RELATED [EC:5.1.3.19]
xref: EC:5.1.3.19
xref: MetaCyc:CHONDROITIN-GLUCURONATE-5-EPIMERASE-RXN
-xref: Reactome:R-HSA-2022052 "DSE converts GlcA to IdoA"
+xref: Reactome:R-HSA-2022052 "Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS)"
xref: RHEA:21084
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.19
+property_value: skos:exactMatch RHEA:21084
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047758
@@ -302313,6 +313512,9 @@
xref: RHEA:24156
is_a: GO:0016301 ! kinase activity
is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor
+property_value: skos:exactMatch EC:2.7.2.14
+property_value: skos:exactMatch RHEA:24156
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047759
@@ -302324,6 +313526,8 @@
xref: EC:1.2.1.57
xref: MetaCyc:BUTANAL-DEHYDROGENASE-RXN
is_a: GO:0004030 ! aldehyde dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.2.1.57
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30270" xsd:anyURI
[Term]
@@ -302348,6 +313552,9 @@
xref: RHEA:13585
is_a: GO:0016301 ! kinase activity
is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor
+property_value: skos:exactMatch EC:2.7.2.7
+property_value: skos:exactMatch RHEA:13585
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047762
@@ -302360,6 +313567,9 @@
xref: MetaCyc:CAFFEATE-34-DIOXYGENASE-RXN
xref: RHEA:22216
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.22
+property_value: skos:exactMatch RHEA:22216
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047763
@@ -302374,6 +313584,9 @@
xref: MetaCyc:RXN-1104
xref: RHEA:20225
is_a: GO:0008171 ! O-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.68
+property_value: skos:exactMatch RHEA:20225
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047764
@@ -302407,6 +313620,9 @@
xref: MetaCyc:CARBAMOYL-SERINE-AMMONIA-LYASE-RXN
xref: RHEA:15445
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.13
+property_value: skos:exactMatch RHEA:15445
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047768
@@ -302422,6 +313638,9 @@
xref: RHEA:14977
is_a: GO:0009975 ! cyclase activity
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.5
+property_value: skos:exactMatch RHEA:14977
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047769
@@ -302435,6 +313654,9 @@
xref: MetaCyc:CARBOXYCYCLOHEXADIENYL-DEHYDRATASE-RXN
xref: RHEA:12536
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.91
+property_value: skos:exactMatch RHEA:12536
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047770
@@ -302447,6 +313669,8 @@
xref: EC:1.2.99.6
xref: MetaCyc:CARBOXYLATE-REDUCTASE-RXN
is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors
+property_value: skos:exactMatch EC:1.2.99.6
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047771
@@ -302460,6 +313684,9 @@
xref: MetaCyc:CARBOXYMETHYLHYDANTOINASE-RXN
xref: RHEA:12028
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.4
+property_value: skos:exactMatch RHEA:12028
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047772
@@ -302473,6 +313700,9 @@
xref: MetaCyc:CARBOXYMETHYLOXYSUCCINATE-LYASE-RXN
xref: RHEA:12336
is_a: GO:0016835 ! carbon-oxygen lyase activity
+property_value: skos:exactMatch EC:4.2.99.12
+property_value: skos:exactMatch RHEA:12336
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047773
@@ -302488,6 +313718,9 @@
xref: MetaCyc:CARNITINAMIDASE-RXN
xref: RHEA:17537
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.73
+property_value: skos:exactMatch RHEA:17537
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047774
@@ -302501,6 +313734,8 @@
xref: EC:1.3.1.37
xref: MetaCyc:CIS-2-ENOYL-COA-REDUCTASE-NADPH-RXN
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.37
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047775
@@ -302512,6 +313747,9 @@
xref: MetaCyc:CITRAMALATE-COA-TRANSFERASE-RXN
xref: RHEA:17621
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.11
+property_value: skos:exactMatch RHEA:17621
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047776
@@ -302532,6 +313770,9 @@
xref: MetaCyc:CITRAMALATE-LYASE-RXN
xref: RHEA:15545
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.22
+property_value: skos:exactMatch RHEA:15545
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047777
@@ -302549,6 +313790,9 @@
xref: MetaCyc:CITRAMALYL-COA-LYASE-RXN
xref: RHEA:22612
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.25
+property_value: skos:exactMatch RHEA:22612
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047778
@@ -302565,6 +313809,9 @@
xref: MetaCyc:CITRATE-PRO-3S-LYASE-THIOLESTERASE-RXN
xref: RHEA:13657
is_a: GO:0016790 ! thiolester hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.16
+property_value: skos:exactMatch RHEA:13657
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047779
@@ -302580,6 +313827,9 @@
xref: MetaCyc:CITRATE--COA-LIGASE-RXN
xref: RHEA:21472
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.18
+property_value: skos:exactMatch RHEA:21472
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047780
@@ -302608,6 +313858,9 @@
xref: MetaCyc:CITRULLINASE-RXN
xref: RHEA:11940
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.20
+property_value: skos:exactMatch RHEA:11940
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047782
@@ -302621,6 +313874,9 @@
xref: MetaCyc:CONIFERIN-BETA-GLUCOSIDASE-RXN
xref: RHEA:12252
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.126
+property_value: skos:exactMatch RHEA:12252
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047783
@@ -302634,6 +313890,9 @@
xref: MetaCyc:RXN66-360
xref: RHEA:11872
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.15.5
+property_value: skos:exactMatch RHEA:11872
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047784
@@ -302649,6 +313908,9 @@
xref: MetaCyc:CORTISOL-O-ACETYLTRANSFERASE-RXN
xref: RHEA:17073
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.27
+property_value: skos:exactMatch RHEA:17073
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047785
@@ -302664,6 +313926,9 @@
xref: MetaCyc:CORTISOL-SULFOTRANSFERASE-RXN
xref: RHEA:11884
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.18
+property_value: skos:exactMatch RHEA:11884
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047786
@@ -302718,9 +313983,18 @@
synonym: "testosterone 5-beta-reductase activity" NARROW [EC:1.3.1.3]
synonym: "testosterone 5beta-reductase activity" NARROW [EC:1.3.1.3]
xref: EC:1.3.1.3
+xref: MetaCyc:CHOLESTENONE-5-BETA-REDUCTASE-RXN
+xref: MetaCyc:CORTISONE-BETA-REDUCTASE-RXN
xref: MetaCyc:RXN-23672
+xref: MetaCyc:RXN-9726
xref: RHEA:54412
is_a: GO:0035671 ! enone reductase activity
+property_value: skos:exactMatch EC:1.3.1.3
+property_value: skos:exactMatch MetaCyc:RXN-23672
+property_value: skos:exactMatch RHEA:54412
+property_value: skos:narrowMatch MetaCyc:CHOLESTENONE-5-BETA-REDUCTASE-RXN
+property_value: skos:narrowMatch MetaCyc:CORTISONE-BETA-REDUCTASE-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-9726
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27695" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -302737,6 +314011,9 @@
xref: MetaCyc:COUMARATE-REDUCTASE-RXN
xref: RHEA:21444
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.11
+property_value: skos:exactMatch RHEA:21444
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047789
@@ -302750,6 +314027,9 @@
xref: MetaCyc:CREATININASE-RXN
xref: RHEA:14533
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.10
+property_value: skos:exactMatch RHEA:14533
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047790
@@ -302764,6 +314044,9 @@
xref: RHEA:12681
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.21
+property_value: skos:exactMatch RHEA:12681
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047791
@@ -302796,7 +314079,10 @@
xref: MetaCyc:RXN-743
xref: RHEA:12853
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.85
+property_value: skos:exactMatch RHEA:12853
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047793
@@ -302811,6 +314097,9 @@
xref: MetaCyc:CYCLOEUCALENOL-CYCLOISOMERASE-RXN
xref: RHEA:22800
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.9
+property_value: skos:exactMatch RHEA:22800
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047794
@@ -302827,6 +314116,9 @@
xref: MetaCyc:CYCLOHEXADIENYL-DEHYDROGENASE-RXN
xref: RHEA:12256
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.43
+property_value: skos:exactMatch RHEA:12256
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047795
@@ -302838,6 +314130,9 @@
xref: MetaCyc:CYCLOHEXANE-12-DIOL-DEHYDROGENASE-RXN
xref: RHEA:18141
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.174
+property_value: skos:exactMatch RHEA:18141
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047796
@@ -302850,7 +314145,10 @@
xref: KEGG_REACTION:R03211
xref: MetaCyc:CYCLOHEXANE-13-DIONE-HYDROLASE-RXN
xref: RHEA:16473
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.10
+property_value: skos:exactMatch RHEA:16473
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047797
@@ -302864,6 +314162,9 @@
xref: MetaCyc:CYCLOHEXANONE-DEHYDROGENASE-RXN
xref: RHEA:21780
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.99.14
+property_value: skos:exactMatch RHEA:21780
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047798
@@ -302878,6 +314179,9 @@
xref: MetaCyc:CYCLOMALTODEXTRINASE-RXN
xref: RHEA:23980
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.54
+property_value: skos:exactMatch RHEA:23980
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047799
@@ -302892,6 +314196,9 @@
xref: MetaCyc:CYCLOPENTANONE-MONOOXYGENASE-RXN
xref: RHEA:15737
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.16
+property_value: skos:exactMatch RHEA:15737
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047800
@@ -302908,6 +314215,9 @@
xref: Reactome:R-HSA-6814153 "ADO oxidises 2AET to HTAU"
xref: RHEA:14409
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.19
+property_value: skos:exactMatch RHEA:14409
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047801
@@ -302922,6 +314232,9 @@
xref: Reactome:R-HSA-9012597 "GOT2 dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu"
xref: RHEA:17441
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.3
+property_value: skos:exactMatch RHEA:17441
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047802
@@ -302936,6 +314249,9 @@
xref: MetaCyc:CYSTEINE-CONJUGATE-TRANSAMINASE-RXN
xref: RHEA:13485
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.75
+property_value: skos:exactMatch RHEA:13485
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047803
@@ -302949,6 +314265,9 @@
xref: MetaCyc:CYSTEINE-LYASE-RXN
xref: RHEA:20916
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.10
+property_value: skos:exactMatch RHEA:20916
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047804
@@ -302964,9 +314283,14 @@
synonym: "L-cysteine-S-conjugate thiol-lyase (deaminating; pyruvate-forming)" RELATED [EC:4.4.1.13]
synonym: "S-alkylcysteine lyase activity" RELATED [EC:4.4.1.13]
xref: EC:4.4.1.13
+xref: MetaCyc:CYSTATHIONINE-BETA-LYASE-RXN
xref: MetaCyc:RXN-6763
xref: RHEA:18121
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.13
+property_value: skos:exactMatch MetaCyc:RXN-6763
+property_value: skos:exactMatch RHEA:18121
+property_value: skos:narrowMatch MetaCyc:CYSTATHIONINE-BETA-LYASE-RXN
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27673" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -302989,6 +314313,9 @@
is_a: GO:0009975 ! cyclase activity
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
relationship: part_of GO:0009190 ! cyclic nucleotide biosynthetic process
+property_value: skos:exactMatch EC:4.6.1.6
+property_value: skos:exactMatch RHEA:14737
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047806
@@ -303004,6 +314331,9 @@
xref: MetaCyc:CYTOCHROME-C3-HYDROGENASE-RXN
xref: RHEA:20625
is_a: GO:0016697 ! oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.12.2.1
+property_value: skos:exactMatch RHEA:20625
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047807
@@ -303021,6 +314351,9 @@
xref: MetaCyc:CYTOKININ-7-BETA-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:23272
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.118
+property_value: skos:exactMatch RHEA:23272
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047808
@@ -303035,6 +314368,9 @@
xref: MetaCyc:D--TARTRATE-DEHYDRATASE-RXN
xref: RHEA:18289
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.81
+property_value: skos:exactMatch RHEA:18289
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047809
@@ -303051,7 +314387,10 @@
xref: RHEA:15089
is_a: GO:0004457 ! lactate dehydrogenase activity
is_a: GO:0033719 ! (2R)-oxo-acid reductase activity
+property_value: skos:exactMatch EC:1.1.99.6
+property_value: skos:exactMatch RHEA:15089
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30132" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047810
@@ -303071,6 +314410,9 @@
xref: MetaCyc:D-ALANINE-AMINOTRANSFERASE-RXN
xref: RHEA:15869
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.21
+property_value: skos:exactMatch RHEA:15869
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047811
@@ -303083,6 +314425,9 @@
xref: MetaCyc:D-ALANINE-GAMMA-GLUTAMYLTRANSFERASE-RXN
xref: RHEA:23556
is_a: GO:0016755 ! aminoacyltransferase activity
+property_value: skos:exactMatch EC:2.3.2.14
+property_value: skos:exactMatch RHEA:23556
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047812
@@ -303096,6 +314441,9 @@
xref: MetaCyc:D-AMINO-ACID-N-ACETYLTRANSFERASE-RXN
xref: RHEA:20704
is_a: GO:0008080 ! N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.36
+property_value: skos:exactMatch RHEA:20704
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047813
@@ -303106,6 +314454,9 @@
xref: MetaCyc:D-ARABINITOL-4-DEHYDROGENASE-RXN
xref: RHEA:17921
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.11
+property_value: skos:exactMatch RHEA:17921
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047814
@@ -303120,6 +314471,9 @@
xref: RHEA:24588
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.54
+property_value: skos:exactMatch RHEA:24588
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047815
@@ -303132,6 +314486,9 @@
xref: MetaCyc:D-ARABINONOLACTONASE-RXN
xref: RHEA:23108
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.30
+property_value: skos:exactMatch RHEA:23108
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047816
@@ -303145,6 +314502,9 @@
xref: MetaCyc:D-ARABINOSE-1-DEHYDROGENASE-RXN
xref: RHEA:20457
is_a: GO:0045290 ! D-arabinose 1-dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.1.1.116
+property_value: skos:exactMatch RHEA:20457
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047817
@@ -303157,6 +314517,9 @@
xref: MetaCyc:D-ARGINASE-RXN
xref: RHEA:12901
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.10
+property_value: skos:exactMatch RHEA:12901
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047818
@@ -303171,6 +314534,9 @@
xref: MetaCyc:D-FUCONATE-HYDRATASE-RXN
xref: RHEA:12949
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.67
+property_value: skos:exactMatch RHEA:12949
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047819
@@ -303183,7 +314549,11 @@
synonym: "D-monoaminodicarboxylic acid oxidase activity" RELATED [EC:1.4.3.15]
xref: EC:1.4.3.15
is_a: GO:0003884 ! D-amino-acid oxidase activity
+property_value: skos:broadMatch MetaCyc:D-ASPARTATE-OXIDASE-RXN
+property_value: skos:broadMatch MetaCyc:D-GLUTAMATE-OXIDASE-RXN
+property_value: skos:exactMatch EC:1.4.3.15
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047820
@@ -303198,6 +314568,9 @@
xref: RHEA:22360
is_a: GO:0009975 ! cyclase activity
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.48
+property_value: skos:exactMatch RHEA:22360
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047821
@@ -303211,7 +314584,11 @@
xref: KEGG_REACTION:R00279
xref: RHEA:10028
is_a: GO:0003884 ! D-amino-acid oxidase activity
+property_value: skos:broadMatch MetaCyc:D-GLUTAMATE-OXIDASE-RXN
+property_value: skos:exactMatch EC:1.4.3.7
+property_value: skos:exactMatch RHEA:10028
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047822
@@ -303223,6 +314600,8 @@
xref: Reactome:R-HSA-1655453 "FMO1:FAD oxidizes HTAU to TAU"
xref: RHEA:69819
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:broadMatch EC:1.14.13.8
+property_value: skos:exactMatch RHEA:69819
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23931" xsd:anyURI
[Term]
@@ -303237,7 +314616,10 @@
xref: MetaCyc:D-GLUTAMYLTRANSFERASE-RXN
xref: RHEA:35623
is_a: GO:0016755 ! aminoacyltransferase activity
+property_value: skos:exactMatch EC:2.3.2.1
+property_value: skos:exactMatch RHEA:35623
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047824
@@ -303248,6 +314630,9 @@
xref: RHEA:12725
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
is_a: GO:0031320 ! hexitol dehydrogenase activity
+property_value: skos:broadMatch EC:1.1.1.15
+property_value: skos:exactMatch RHEA:12725
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047825
@@ -303261,6 +314646,9 @@
xref: MetaCyc:D-LACTATE-2-SULFATASE-RXN
xref: RHEA:20337
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.17
+property_value: skos:exactMatch RHEA:20337
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047826
@@ -303271,11 +314659,23 @@
synonym: "lysine 5,6-aminomutase activity" RELATED []
xref: EC:5.4.3.3
xref: KEGG_REACTION:R02852
+xref: KEGG_REACTION:R03275
xref: MetaCyc:BETA-LYSINE-56-AMINOMUTASE-RXN
+xref: MetaCyc:D-LYSINE-56-AMINOMUTASE-RXN
+xref: RHEA:18241
+xref: RHEA:21736
is_a: GO:0016869 ! intramolecular aminotransferase activity
+property_value: skos:exactMatch EC:5.4.3.3
+property_value: skos:exactMatch KEGG_REACTION:R02852
+property_value: skos:exactMatch MetaCyc:BETA-LYSINE-56-AMINOMUTASE-RXN
+property_value: skos:narrowMatch KEGG_REACTION:R03275
+property_value: skos:narrowMatch MetaCyc:D-LYSINE-56-AMINOMUTASE-RXN
+property_value: skos:narrowMatch RHEA:18241
+property_value: skos:narrowMatch RHEA:21736
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24927" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27672" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047827
@@ -303292,6 +314692,9 @@
xref: MetaCyc:D-LYSOPINE-DEHYDROGENASE-RXN
xref: RHEA:17625
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.16
+property_value: skos:exactMatch RHEA:17625
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047828
@@ -303305,6 +314708,9 @@
xref: MetaCyc:D-LYXOSE-KETOL-ISOMERASE-RXN
xref: RHEA:14201
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.15
+property_value: skos:exactMatch RHEA:14201
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047829
@@ -303321,6 +314727,9 @@
xref: MetaCyc:D-NOPALINE-DEHYDROGENASE-RXN
xref: RHEA:19637
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.19
+property_value: skos:exactMatch RHEA:19637
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047830
@@ -303337,6 +314746,9 @@
xref: MetaCyc:D-OCTOPINE-DEHYDROGENASE-RXN
xref: RHEA:16285
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.11
+property_value: skos:exactMatch RHEA:16285
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047831
@@ -303350,6 +314762,9 @@
xref: MetaCyc:ORNMUTST-RXN
xref: RHEA:14893
is_a: GO:0016869 ! intramolecular aminotransferase activity
+property_value: skos:exactMatch EC:5.4.3.5
+property_value: skos:exactMatch RHEA:14893
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047832
@@ -303363,6 +314778,9 @@
xref: MetaCyc:D-PINITOL-DEHYDROGENASE-RXN
xref: RHEA:20437
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.142
+property_value: skos:exactMatch RHEA:20437
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047833
@@ -303376,6 +314794,9 @@
xref: MetaCyc:D-SORBITOL-DEHYDROGENASE-RXN
xref: RHEA:21320
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.21
+property_value: skos:exactMatch RHEA:21320
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047834
@@ -303391,6 +314812,9 @@
xref: MetaCyc:D-THREO-ALDOSE-1-DEHYDROGENASE-RXN
xref: RHEA:19645
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.122
+property_value: skos:exactMatch RHEA:19645
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047835
@@ -303405,6 +314829,9 @@
xref: MetaCyc:D-TRYPTOPHAN-N-ACETYLTRANSFERASE-RXN
xref: RHEA:10060
is_a: GO:0047812 ! D-amino-acid N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.34
+property_value: skos:exactMatch RHEA:10060
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047836
@@ -303417,6 +314844,9 @@
xref: MetaCyc:D-TRYPTOPHAN-N-MALONYLTRANSFERASE-RXN
xref: RHEA:23320
is_a: GO:0050735 ! N-malonyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.112
+property_value: skos:exactMatch RHEA:23320
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047837
@@ -303432,6 +314862,9 @@
xref: MetaCyc:D-XYLOSE-1-DEHYDROGENASE-NADP+-RXN
xref: RHEA:22000
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.179
+property_value: skos:exactMatch RHEA:22000
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047838
@@ -303449,7 +314882,10 @@
xref: MetaCyc:D-XYLOSE-1-DEHYDROGENASE-RXN
xref: RHEA:13861
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.175
+property_value: skos:exactMatch RHEA:13861
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047839
@@ -303462,6 +314898,8 @@
xref: MetaCyc:DATPDGTP--DNA-PURINE-TRANSFERASE-RXN
is_a: GO:0016769 ! transferase activity, transferring nitrogenous groups
is_a: GO:0140097 ! catalytic activity, acting on DNA
+property_value: skos:exactMatch EC:2.6.99.1
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047840
@@ -303479,6 +314917,9 @@
xref: Reactome:R-HSA-6786257 "DCTPP1 hydrolyses 5idCTP"
xref: RHEA:22636
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:exactMatch EC:3.6.1.12
+property_value: skos:exactMatch RHEA:22636
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047841
@@ -303497,6 +314938,9 @@
xref: RHEA:10788
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.13
+property_value: skos:exactMatch RHEA:10788
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047842
@@ -303513,6 +314957,9 @@
xref: Reactome:R-HSA-5662473 "KGPDC decarboxylates 3-dehydro-L-gulonate to L-xylulose"
xref: RHEA:11084
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.34
+property_value: skos:exactMatch RHEA:11084
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047843
@@ -303529,6 +314976,9 @@
xref: MetaCyc:DEHYDROGLUCONATE-DEHYDROGENASE-RXN
xref: RHEA:12368
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.4
+property_value: skos:exactMatch RHEA:12368
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047844
@@ -303552,6 +315002,9 @@
xref: MetaCyc:DEOXYLIMONATE-A-RING-LACTONASE-RXN
xref: RHEA:14997
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.46
+property_value: skos:exactMatch RHEA:14997
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047846
@@ -303565,6 +315018,9 @@
xref: MetaCyc:DEOXYNUCLEOTIDE-3-PHOSPHATASE-RXN
xref: RHEA:10092
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.34
+property_value: skos:exactMatch RHEA:10092
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047847
@@ -303574,6 +315030,10 @@
xref: MetaCyc:URA-PHOSPH-RXN
xref: RHEA:22824
is_a: GO:0016154 ! pyrimidine-nucleoside phosphorylase activity
+property_value: skos:broadMatch EC:2.4.2.2
+property_value: skos:broadMatch EC:2.4.2.3
+property_value: skos:exactMatch MetaCyc:URA-PHOSPH-RXN
+property_value: skos:exactMatch RHEA:22824
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25966" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
@@ -303608,7 +315068,15 @@
xref: EC:2.4.1.5
xref: MetaCyc:2.4.1.125-RXN
xref: RHEA:18825
+xref: RHEA:57036
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:broadMatch EC:2.4.1.125
+property_value: skos:broadMatch EC:2.4.1.140
+property_value: skos:broadMatch MetaCyc:2.4.1.140-RXN
+property_value: skos:exactMatch EC:2.4.1.5
+property_value: skos:exactMatch MetaCyc:2.4.1.125-RXN
+property_value: skos:exactMatch RHEA:18825
+property_value: skos:narrowMatch RHEA:57036
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
[Term]
@@ -303625,6 +315093,9 @@
xref: MetaCyc:DIAMINOPIMELATE-DEHYDROGENASE-RXN
xref: RHEA:13561
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.16
+property_value: skos:exactMatch RHEA:13561
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047851
@@ -303637,6 +315108,9 @@
xref: MetaCyc:DICARBOXYLATE--COA-LIGASE-RXN
xref: RHEA:14289
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.23
+property_value: skos:exactMatch RHEA:14289
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047852
@@ -303651,6 +315125,9 @@
xref: MetaCyc:DIFFERIC-TRANSFERRIN-REDUCTASE-RXN
xref: RHEA:13841
is_a: GO:0016723 ! oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.16.1.2
+property_value: skos:exactMatch RHEA:13841
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047853
@@ -303663,6 +315140,9 @@
xref: MetaCyc:DIFRUCTOSE-ANHYDRIDE-SYNTHASE-RXN
xref: RHEA:15041
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:4.2.1.179
+property_value: skos:exactMatch RHEA:15041
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047854
@@ -303675,6 +315155,9 @@
xref: MetaCyc:DIGUANIDINOBUTANASE-RXN
xref: RHEA:13597
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.20
+property_value: skos:exactMatch RHEA:13597
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047855
@@ -303688,6 +315171,9 @@
xref: MetaCyc:DIHYDROBUNOLOL-DEHYDROGENASE-RXN
xref: RHEA:15925
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.160
+property_value: skos:exactMatch RHEA:15925
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047856
@@ -303702,6 +315188,9 @@
xref: MetaCyc:DIHYDROCOUMARIN-LIPASE-RXN
xref: RHEA:10360
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.35
+property_value: skos:exactMatch RHEA:10360
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047857
@@ -303714,6 +315203,9 @@
xref: MetaCyc:DIHYDROURACIL-OXIDASE-RXN
xref: RHEA:12384
is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.3.3.7
+property_value: skos:exactMatch RHEA:12384
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047858
@@ -303727,6 +315219,9 @@
xref: MetaCyc:DIHYDROXYFUMARATE-DECARBOXYLASE-RXN
xref: RHEA:13845
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.54
+property_value: skos:exactMatch RHEA:13845
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047859
@@ -303754,7 +315249,10 @@
xref: MetaCyc:DIIODOPHENYLPYRUVATE-REDUCTASE-RXN
xref: RHEA:20293
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.96
+property_value: skos:exactMatch RHEA:20293
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30138" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047861
@@ -303770,6 +315268,9 @@
xref: MetaCyc:DIIODOTYROSINE-AMINOTRANSFERASE-RXN
xref: RHEA:19781
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.24
+property_value: skos:exactMatch RHEA:19781
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047862
@@ -303793,8 +315294,11 @@
xref: KEGG_REACTION:R01533
xref: MetaCyc:DIISOPROPYL-FLUOROPHOSPHATASE-RXN
xref: RHEA:24100
-is_a: GO:0016824 ! hydrolase activity, acting on acid halide bonds
+is_a: GO:0016824 ! hydrolase activity, acting on halide bonds
+property_value: skos:exactMatch EC:3.8.2.2
+property_value: skos:exactMatch RHEA:24100
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28006" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047863
@@ -303808,7 +315312,10 @@
xref: MetaCyc:DIMETHYLALLYLCISTRANSFERASE-RXN
xref: RHEA:11328
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.28
+property_value: skos:exactMatch RHEA:11328
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047864
@@ -303824,6 +315331,9 @@
xref: MetaCyc:DIMETHYLANILINE-N-OXIDE-ALDOLASE-RXN
xref: RHEA:19321
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.24
+property_value: skos:exactMatch RHEA:19321
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047865
@@ -303840,6 +315350,9 @@
xref: Reactome:R-HSA-6797653 "DMGDH:FAD oxidatively demethylates DMGLY to SARC"
xref: RHEA:52856
is_a: GO:0046997 ! oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor
+property_value: skos:exactMatch EC:1.5.8.4
+property_value: skos:exactMatch RHEA:52856
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047866
@@ -303852,6 +315365,9 @@
xref: MetaCyc:DIMETHYLGLYCINE-OXIDASE-RXN
xref: RHEA:17077
is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.5.3.10
+property_value: skos:exactMatch RHEA:17077
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047867
@@ -303865,6 +315381,9 @@
xref: MetaCyc:DIMETHYLMALATE-DEHYDROGENASE-RXN
xref: RHEA:13321
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.84
+property_value: skos:exactMatch RHEA:13321
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047868
@@ -303878,6 +315397,9 @@
xref: MetaCyc:DIMETHYLMALEATE-HYDRATASE-RXN
xref: RHEA:20253
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.85
+property_value: skos:exactMatch RHEA:20253
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047869
@@ -303892,6 +315414,9 @@
xref: MetaCyc:DIMETHYLPROPIOTHETIN-DETHIOMETHYLASE-RXN
xref: RHEA:19965
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.3
+property_value: skos:exactMatch RHEA:19965
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047870
@@ -303906,6 +315431,9 @@
xref: MetaCyc:DISCADENINE-SYNTHASE-RXN
xref: RHEA:19581
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.24
+property_value: skos:exactMatch RHEA:19581
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047871
@@ -303921,6 +315449,9 @@
xref: MetaCyc:DISULFOGLUCOSAMINE-6-SULFATASE-RXN
xref: RHEA:15517
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.11
+property_value: skos:exactMatch RHEA:15517
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047872
@@ -303933,6 +315464,9 @@
xref: MetaCyc:DOLICHOL-O-ACYLTRANSFERASE-RXN
xref: RHEA:16685
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.123
+property_value: skos:exactMatch RHEA:16685
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047873
@@ -303954,6 +315488,9 @@
xref: MetaCyc:DOLICHYL-PHOSPHATASE-RXN
xref: RHEA:13797
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.51
+property_value: skos:exactMatch RHEA:13797
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047874
@@ -303969,6 +315506,8 @@
xref: Reactome:R-HSA-446200 "DOLPP1 dephosphorylates DOLDP to DOLP"
xref: RHEA:14385
is_a: GO:0120556 ! polyprenyl diphosphate phosphatase activity
+property_value: skos:exactMatch EC:3.6.1.43
+property_value: skos:exactMatch RHEA:14385
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30245" xsd:anyURI
[Term]
@@ -303983,6 +315522,9 @@
xref: MetaCyc:ECDYSONE-OXIDASE-RXN
xref: RHEA:11796
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.16
+property_value: skos:exactMatch RHEA:11796
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047876
@@ -303998,6 +315540,9 @@
xref: MetaCyc:ENDOGLYCOSYLCERAMIDASE-RXN
xref: RHEA:22288
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.123
+property_value: skos:exactMatch RHEA:22288
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047877
@@ -304010,6 +315555,9 @@
xref: MetaCyc:EPHEDRINE-DEHYDROGENASE-RXN
xref: RHEA:16289
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.18
+property_value: skos:exactMatch RHEA:16289
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047878
@@ -304024,6 +315572,9 @@
xref: RHEA:20708
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.27
+property_value: skos:exactMatch RHEA:20708
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047879
@@ -304036,6 +315587,9 @@
xref: MetaCyc:ERYTHRONOLIDE-SYNTHASE-RXN
xref: RHEA:23068
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.94
+property_value: skos:exactMatch RHEA:23068
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047880
@@ -304049,7 +315603,10 @@
xref: MetaCyc:RXN-17773
xref: RHEA:18005
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.162
+property_value: skos:exactMatch RHEA:18005
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047881
@@ -304066,8 +315623,14 @@
synonym: "estradiol 17alpha-oxidoreductase activity" RELATED [EC:1.1.1.148]
xref: EC:1.1.1.148
xref: MetaCyc:ESTRADIOL-17-ALPHA-DEHYDROGENASE-RXN
+xref: RHEA:16701
+xref: RHEA:16705
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.148
+property_value: skos:narrowMatch RHEA:16701
+property_value: skos:narrowMatch RHEA:16705
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047882
@@ -304086,7 +315649,10 @@
xref: RHEA:19137
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.11
+property_value: skos:exactMatch RHEA:19137
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29311" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047883
@@ -304098,6 +315664,9 @@
xref: MetaCyc:ETHANOLAMINE-OXIDASE-RXN
xref: RHEA:18581
is_a: GO:0052595 ! aliphatic amine oxidase activity
+property_value: skos:exactMatch EC:1.4.3.8
+property_value: skos:exactMatch RHEA:18581
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047884
@@ -304115,6 +315684,9 @@
xref: MetaCyc:FAD-PYROPHOSPHATASE-RXN
xref: RHEA:13889
is_a: GO:0004551 ! dinucleotide phosphatase activity
+property_value: skos:exactMatch EC:3.6.1.18
+property_value: skos:exactMatch RHEA:13889
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047885
@@ -304128,6 +315700,9 @@
xref: MetaCyc:FARNESOL-2-ISOMERASE-RXN
xref: RHEA:13401
is_a: GO:0016859 ! cis-trans isomerase activity
+property_value: skos:exactMatch EC:5.2.1.9
+property_value: skos:exactMatch RHEA:13401
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047886
@@ -304142,6 +315717,9 @@
xref: MetaCyc:FARNESOL-DEHYDROGENASE-RXN
xref: RHEA:14697
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.216
+property_value: skos:exactMatch RHEA:14697
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047887
@@ -304157,6 +315735,9 @@
xref: RHEA:21544
is_a: GO:0016301 ! kinase activity
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
+property_value: skos:exactMatch EC:2.7.4.18
+property_value: skos:exactMatch RHEA:21544
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047888
@@ -304171,6 +315752,9 @@
xref: MetaCyc:FATTY-ACID-PEROXIDASE-RXN
xref: RHEA:23960
is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch EC:1.11.1.3
+property_value: skos:exactMatch RHEA:23960
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047889
@@ -304186,6 +315770,8 @@
xref: RHEA:21828
is_a: GO:0008940 ! nitrate reductase activity
is_a: GO:0016664 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.7.7.2
+property_value: skos:exactMatch RHEA:21828
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25967" xsd:anyURI
[Term]
@@ -304199,6 +315785,9 @@
xref: MetaCyc:FLAVANONE-4-REDUCTASE-RXN
xref: RHEA:11228
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.234
+property_value: skos:exactMatch RHEA:11228
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047891
@@ -304218,6 +315807,9 @@
xref: MetaCyc:FLAVONE-7-O-BETA-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:19577
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.81
+property_value: skos:exactMatch RHEA:19577
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047892
@@ -304232,6 +315824,9 @@
xref: RHEA:19153
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.25
+property_value: skos:exactMatch RHEA:19153
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047893
@@ -304249,6 +315844,9 @@
xref: MetaCyc:FLAVONOL-3-O-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:22300
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.91
+property_value: skos:exactMatch RHEA:22300
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047894
@@ -304263,6 +315861,9 @@
xref: MetaCyc:FLAVONOL-3-SULFOTRANSFERASE-RXN
xref: RHEA:13453
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.25
+property_value: skos:exactMatch RHEA:13453
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047895
@@ -304277,6 +315878,9 @@
xref: MetaCyc:RXN-11453
xref: RHEA:19221
is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors
+property_value: skos:exactMatch EC:1.2.98.1
+property_value: skos:exactMatch RHEA:19221
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047896
@@ -304291,6 +315895,9 @@
xref: MetaCyc:FORMALDEHYDE-TRANSKETOLASE-RXN
xref: RHEA:24264
is_a: GO:0016744 ! transketolase or transaldolase activity
+property_value: skos:exactMatch EC:2.2.1.3
+property_value: skos:exactMatch RHEA:24264
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047897
@@ -304305,6 +315912,9 @@
xref: MetaCyc:FORMATE--DIHYDROFOLATE-LIGASE-RXN
xref: RHEA:24328
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.17
+property_value: skos:exactMatch RHEA:24328
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047898
@@ -304317,6 +315927,9 @@
xref: MetaCyc:FORMATE-DEHYDROGENASE-CYTOCHROME-RXN
xref: RHEA:21520
is_a: GO:0016622 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.2.2.1
+property_value: skos:exactMatch RHEA:21520
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047899
@@ -304330,6 +315943,9 @@
xref: MetaCyc:FORMATE-DEHYDROGENASE-NADP+-RXN
xref: RHEA:12000
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.17.1.10
+property_value: skos:exactMatch RHEA:12000
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047900
@@ -304343,6 +315959,9 @@
xref: RHEA:16009
is_a: GO:0016301 ! kinase activity
is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor
+property_value: skos:exactMatch EC:2.7.2.6
+property_value: skos:exactMatch RHEA:16009
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047901
@@ -304366,6 +315985,9 @@
xref: MetaCyc:FORMYLASPARTATE-DEFORMYLASE-RXN
xref: RHEA:22040
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.8
+property_value: skos:exactMatch RHEA:22040
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047903
@@ -304383,6 +316005,9 @@
xref: MetaCyc:FRUCTOSE-5-DEHYDROGENASE-NADP+-RXN
xref: RHEA:14069
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.124
+property_value: skos:exactMatch RHEA:14069
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047904
@@ -304395,7 +316020,10 @@
xref: MetaCyc:FRUCTOSE-5-DEHYDROGENASE-RXN
xref: RHEA:22304
is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.1.5.14
+property_value: skos:exactMatch RHEA:22304
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24927" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047905
@@ -304408,6 +316036,9 @@
xref: MetaCyc:FRUCTOSE-6-PHOSPHATE-PHOSPHOKETOLASE-RXN
xref: RHEA:12196
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.22
+property_value: skos:exactMatch RHEA:12196
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047906
@@ -304421,6 +316052,9 @@
xref: MetaCyc:FUCOSTEROL-EPOXIDE-LYASE-RXN
xref: RHEA:10884
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.33
+property_value: skos:exactMatch RHEA:10884
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047907
@@ -304433,6 +316067,9 @@
xref: MetaCyc:FURYLFURAMIDE-ISOMERASE-RXN
xref: RHEA:21848
is_a: GO:0016859 ! cis-trans isomerase activity
+property_value: skos:exactMatch EC:5.2.1.6
+property_value: skos:exactMatch RHEA:21848
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047908
@@ -304446,6 +316083,9 @@
xref: MetaCyc:FUSARININE-C-ORNITHINESTERASE-RXN
xref: RHEA:20165
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.48
+property_value: skos:exactMatch RHEA:20165
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047909
@@ -304457,6 +316097,8 @@
xref: EC:2.3.1.134
xref: MetaCyc:GALACTOLIPID-O-ACYLTRANSFERASE-RXN
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.134
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047910
@@ -304469,6 +316111,9 @@
xref: MetaCyc:GALACTOSE-1-DEHYDROGENASE-NADP+-RXN
xref: RHEA:18625
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.120
+property_value: skos:exactMatch RHEA:18625
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047911
@@ -304487,6 +316132,9 @@
xref: MetaCyc:GALACTURAN-14-ALPHA-GALACTURONIDASE-RXN
xref: RHEA:14117
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.67
+property_value: skos:exactMatch RHEA:14117
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047912
@@ -304501,6 +316149,9 @@
xref: RHEA:12965
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.44
+property_value: skos:exactMatch RHEA:12965
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047913
@@ -304519,6 +316170,9 @@
xref: MetaCyc:GALLATE-1-BETA-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:15249
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.136
+property_value: skos:exactMatch RHEA:15249
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047914
@@ -304533,6 +316187,9 @@
xref: MetaCyc:GAMMA-GLUTAMYLHISTAMINE-SYNTHASE-RXN
xref: RHEA:18881
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.18
+property_value: skos:exactMatch RHEA:18881
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047915
@@ -304554,6 +316211,9 @@
xref: MetaCyc:GANGLIOSIDE-GALACTOSYLTRANSFERASE-RXN
xref: RHEA:16773
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.62
+property_value: skos:exactMatch RHEA:16773
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047916
@@ -304565,6 +316225,8 @@
xref: EC:1.1.1.135
xref: MetaCyc:GDP-6-DEOXY-D-TALOSE-4-DEHYDROGENASE-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.135
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047917
@@ -304581,6 +316243,9 @@
xref: MetaCyc:GDP-GLUCOSIDASE-RXN
xref: RHEA:15049
is_a: GO:0015926 ! glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.42
+property_value: skos:exactMatch RHEA:15049
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047918
@@ -304592,8 +316257,14 @@
synonym: "guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate L-galactose epimerase activity" RELATED [EC:5.1.3.18]
xref: EC:5.1.3.18
xref: MetaCyc:RXN-7772
+xref: RHEA:63800
+xref: RHEA:63804
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.18
+property_value: skos:narrowMatch RHEA:63800
+property_value: skos:narrowMatch RHEA:63804
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23098" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047919
@@ -304610,6 +316281,9 @@
xref: MetaCyc:GDP-MANNOSE-6-DEHYDROGENASE-RXN
xref: RHEA:21728
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.132
+property_value: skos:exactMatch RHEA:21728
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047920
@@ -304622,6 +316296,9 @@
xref: MetaCyc:GEISSOSCHIZINE-DEHYDROGENASE-RXN
xref: RHEA:11376
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.36
+property_value: skos:exactMatch RHEA:11376
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047921
@@ -304639,6 +316316,9 @@
xref: MetaCyc:GENTAMICIN-2-N-ACETYLTRANSFERASE-RXN
xref: RHEA:24516
is_a: GO:0034069 ! aminoglycoside N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.59
+property_value: skos:exactMatch RHEA:24516
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047922
@@ -304655,6 +316335,9 @@
xref: MetaCyc:GENTISATE-12-DIOXYGENASE-RXN
xref: RHEA:18237
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.4
+property_value: skos:exactMatch RHEA:18237
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047923
@@ -304669,6 +316352,9 @@
xref: MetaCyc:GENTISATE-DECARBOXYLASE-RXN
xref: RHEA:21312
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.62
+property_value: skos:exactMatch RHEA:21312
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047924
@@ -304681,6 +316367,9 @@
xref: RHEA:14521
xref: UM-BBD_reactionID:r1163
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.183
+property_value: skos:exactMatch RHEA:14521
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047925
@@ -304696,6 +316385,9 @@
xref: RHEA:17701
xref: UM-BBD_reactionID:r1166
is_a: GO:0016421 ! CoA carboxylase activity
+property_value: skos:exactMatch EC:6.4.1.5
+property_value: skos:exactMatch RHEA:17701
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047926
@@ -304713,6 +316405,9 @@
xref: RHEA:18209
is_a: GO:0009975 ! cyclase activity
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.8
+property_value: skos:exactMatch RHEA:18209
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047927
@@ -304738,6 +316433,9 @@
xref: MetaCyc:GIBBERELLIN-BETA-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:20025
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.176
+property_value: skos:exactMatch RHEA:20025
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047929
@@ -304752,6 +316450,9 @@
xref: MetaCyc:GLUCONATE-DEHYDRATASE-RXN
xref: RHEA:21612
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.39
+property_value: skos:exactMatch RHEA:21612
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047930
@@ -304774,6 +316475,9 @@
xref: MetaCyc:4.3.1.21-RXN
xref: RHEA:12488
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.9
+property_value: skos:exactMatch RHEA:12488
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047931
@@ -304789,7 +316493,10 @@
xref: RHEA:10948
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.8
+property_value: skos:exactMatch RHEA:10948
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27918" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047932
@@ -304804,6 +316511,9 @@
xref: MetaCyc:GLUCOSAMINE-N-ACETYLTRANSFERASE-RXN
xref: RHEA:21332
is_a: GO:0008080 ! N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.3
+property_value: skos:exactMatch RHEA:21332
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047933
@@ -304821,6 +316531,9 @@
xref: RHEA:16769
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.106
+property_value: skos:exactMatch RHEA:16769
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047934
@@ -304834,7 +316547,10 @@
xref: MetaCyc:GLUCOSE-1-DEHYDROGENASE-NAD+-RXN
xref: RHEA:14293
is_a: GO:0047936 ! glucose 1-dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.1.1.118
+property_value: skos:exactMatch RHEA:14293
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25441" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047935
@@ -304849,7 +316565,10 @@
xref: MetaCyc:GLUCOSE-1-DEHYDROGENASE-NADP+-RXN
xref: RHEA:14405
is_a: GO:0047936 ! glucose 1-dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.1.1.119
+property_value: skos:exactMatch RHEA:14405
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25441" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047936
@@ -304864,8 +316583,10 @@
xref: MetaCyc:GLUCOSE-1-DEHYDROGENASE-RXN
is_a: GO:0004344 ! glucose dehydrogenase activity
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.47
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22585" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25441" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047937
@@ -304880,6 +316601,9 @@
xref: RHEA:16397
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.41
+property_value: skos:exactMatch RHEA:16397
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047938
@@ -304892,6 +316616,9 @@
xref: MetaCyc:GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXN
xref: RHEA:16249
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.15
+property_value: skos:exactMatch RHEA:16249
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047939
@@ -304911,6 +316638,9 @@
xref: Reactome:R-HSA-5661256 "AKR1A1 reduces D-glucuronate to L-gulonate"
xref: RHEA:14909
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.19
+property_value: skos:exactMatch RHEA:14909
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047940
@@ -304926,6 +316656,9 @@
xref: RHEA:17005
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.43
+property_value: skos:exactMatch RHEA:17005
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047941
@@ -304937,6 +316670,9 @@
xref: MetaCyc:GLUCURONOLACTONE-REDUCTASE-RXN
xref: RHEA:18925
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.20
+property_value: skos:exactMatch RHEA:18925
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047942
@@ -304953,6 +316689,9 @@
xref: MetaCyc:RXN-12905
xref: RHEA:20525
is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity
+property_value: skos:exactMatch EC:6.3.1.6
+property_value: skos:exactMatch RHEA:20525
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047943
@@ -304966,6 +316705,9 @@
xref: MetaCyc:GLUTAMATE--METHYLAMINE-LIGASE-RXN
xref: RHEA:17117
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.12
+property_value: skos:exactMatch RHEA:17117
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047944
@@ -304999,6 +316741,9 @@
xref: Reactome:R-HSA-893616 "glutamine + pyruvate => 2-oxoglutaramate + alanine"
xref: RHEA:10400
is_a: GO:0070548 ! L-glutamine aminotransferase activity
+property_value: skos:exactMatch EC:2.6.1.15
+property_value: skos:exactMatch RHEA:10400
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047946
@@ -305010,6 +316755,9 @@
xref: MetaCyc:GLUTAMINE-N-ACYLTRANSFERASE-RXN
xref: RHEA:18469
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.68
+property_value: skos:exactMatch RHEA:18469
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047947
@@ -305023,6 +316771,9 @@
xref: MetaCyc:GLUTAMINE-N-PHENYLACETYLTRANSFERASE-RXN
xref: RHEA:21844
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.14
+property_value: skos:exactMatch RHEA:21844
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047948
@@ -305037,6 +316788,9 @@
xref: MetaCyc:GLUTARATE--COA-LIGASE-RXN
xref: RHEA:14169
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.6
+property_value: skos:exactMatch RHEA:14169
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047949
@@ -305060,6 +316814,9 @@
xref: MetaCyc:GLUTATHIONE-OXIDASE-RXN
xref: RHEA:24112
is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.8.3.3
+property_value: skos:exactMatch RHEA:24112
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047951
@@ -305074,6 +316831,9 @@
xref: MetaCyc:GLUTATHIONE-THIOESTERASE-RXN
xref: RHEA:22708
is_a: GO:0016790 ! thiolester hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.7
+property_value: skos:exactMatch RHEA:22708
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047952
@@ -305096,6 +316856,7 @@
xref: MetaCyc:GLYC3PDEHYDROGBIOSYN-RXN
xref: Reactome:R-HSA-75889 "DHAP is converted to G3P by GPD1/GPD1L"
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.94
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21790" xsd:anyURI
created_by: bf
creation_date: 2013-09-30T10:37:46Z
@@ -305115,6 +316876,8 @@
xref: MetaCyc:GLYCEROL-2-DEHYDROGENASE-NADP+-RXN
xref: RHEA:12753
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.156
+property_value: skos:exactMatch RHEA:12753
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
[Term]
@@ -305131,6 +316894,9 @@
xref: MetaCyc:GLYCEROL-2-PHOSPHATASE-RXN
xref: RHEA:13105
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.19
+property_value: skos:exactMatch RHEA:13105
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047955
@@ -305144,6 +316910,9 @@
xref: MetaCyc:GLYCEROL-DEHYDROGENASE-ACCEPTOR-RXN
xref: RHEA:17493
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.22
+property_value: skos:exactMatch RHEA:17493
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047956
@@ -305156,7 +316925,10 @@
xref: MetaCyc:GLYCEROL-DEHYDROGENASE-NADP+-RXN
xref: RHEA:23592
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.72
+property_value: skos:exactMatch RHEA:23592
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047957
@@ -305169,6 +316941,9 @@
xref: MetaCyc:ISOFLAVONE-2-HYDROXYLASE-RXN
xref: RHEA:12388
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.89
+property_value: skos:exactMatch RHEA:12388
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047958
@@ -305186,6 +316961,9 @@
xref: MetaCyc:GLYCINE-AMINOTRANSFERASE-RXN
xref: RHEA:14089
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.4
+property_value: skos:exactMatch RHEA:14089
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047959
@@ -305199,6 +316977,9 @@
xref: MetaCyc:GLYCINE-DEHYDROGENASE-CYTOCHROME-RXN
xref: RHEA:16909
is_a: GO:0016640 ! oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.4.2.1
+property_value: skos:exactMatch RHEA:16909
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047960
@@ -305210,6 +316991,9 @@
xref: MetaCyc:GLYCINE-DEHYDROGENASE-RXN
xref: RHEA:15721
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.10
+property_value: skos:exactMatch RHEA:15721
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047961
@@ -305224,6 +317008,9 @@
xref: Reactome:R-HSA-2534040 "Unknown NAT N-acylates Gly in GNAT1"
xref: RHEA:19869
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.13
+property_value: skos:exactMatch RHEA:19869
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047962
@@ -305241,6 +317028,9 @@
xref: Reactome:R-HSA-9750001 "GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid"
xref: RHEA:18493
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.71
+property_value: skos:exactMatch RHEA:18493
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047963
@@ -305259,6 +317049,9 @@
xref: MetaCyc:GLYCINE-N-CHOLOYLTRANSFERASE-RXN
xref: RHEA:14001
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.65
+property_value: skos:exactMatch RHEA:14001
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047964
@@ -305272,7 +317065,10 @@
xref: MetaCyc:GLYCOLATE-REDUCTASE-RXN
xref: RHEA:18229
is_a: GO:0106345 ! glyoxylate reductase activity
+property_value: skos:exactMatch EC:1.1.1.26
+property_value: skos:exactMatch RHEA:18229
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047965
@@ -305285,6 +317081,8 @@
xref: MetaCyc:GLYCOPROTEIN-O-FATTY-ACYLTRANSFERASE-RXN
is_a: GO:0016416 ! O-palmitoyltransferase activity
is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein
+property_value: skos:exactMatch EC:2.3.1.142
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047966
@@ -305299,6 +317097,9 @@
xref: MetaCyc:GLYCOSULFATASE-RXN
xref: RHEA:19145
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.3
+property_value: skos:exactMatch RHEA:19145
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047967
@@ -305315,6 +317116,9 @@
xref: MetaCyc:GLYCYRRHIZINATE-BETA-GLUCURONIDASE-RXN
xref: RHEA:17369
is_a: GO:0046574 ! glucuronidase activity
+property_value: skos:exactMatch EC:3.2.1.128
+property_value: skos:exactMatch RHEA:17369
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30698" xsd:anyURI
[Term]
@@ -305328,6 +317132,9 @@
xref: MetaCyc:GLYOXYLATE-DEHYDROGENASE-ACYLATING-RXN
xref: RHEA:21024
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.17
+property_value: skos:exactMatch RHEA:21024
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047969
@@ -305341,6 +317148,9 @@
xref: Reactome:R-HSA-389862 "Conversion of glyoxylate to oxalate"
xref: RHEA:14837
is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.2.3.5
+property_value: skos:exactMatch RHEA:14837
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047970
@@ -305354,6 +317164,9 @@
xref: MetaCyc:GUANIDINOACETASE-RXN
xref: RHEA:23268
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.2
+property_value: skos:exactMatch RHEA:23268
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047971
@@ -305372,6 +317185,9 @@
xref: MetaCyc:GUANIDINOBUTYRASE-RXN
xref: RHEA:19501
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.7
+property_value: skos:exactMatch RHEA:19501
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047972
@@ -305386,6 +317202,9 @@
xref: MetaCyc:GUANIDINOPROPIONASE-RXN
xref: RHEA:16029
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.17
+property_value: skos:exactMatch RHEA:16029
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047973
@@ -305401,6 +317220,9 @@
xref: RHEA:14145
is_a: GO:0016301 ! kinase activity
is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor
+property_value: skos:exactMatch EC:2.7.3.1
+property_value: skos:exactMatch RHEA:14145
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047974
@@ -305414,18 +317236,25 @@
xref: RHEA:12861
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.15
+property_value: skos:exactMatch RHEA:12861
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047975
name: guanosine phosphorylase activity
namespace: molecular_function
-def: "Catalysis of the reaction: guanosine + phosphate = guanine + D-ribose 1-phosphate." [EC:2.4.2.15]
+def: "Catalysis of the reaction: guanosine + phosphate = alpha-D-ribose 1-phosphate + guanine." [RHEA:13233]
synonym: "guanosine:phosphate alpha-D-ribosyltransferase activity" RELATED [EC:2.4.2.15]
synonym: "guanosine:phosphate D-ribosyltransferase activity" RELATED [EC:2.4.2.15]
xref: EC:2.4.2.15
xref: MetaCyc:RXN0-5199
xref: RHEA:13233
-is_a: GO:0016763 ! pentosyltransferase activity
+is_a: GO:0004731 ! purine-nucleoside phosphorylase activity
+property_value: skos:exactMatch EC:2.4.2.15
+property_value: skos:exactMatch MetaCyc:RXN0-5199
+property_value: skos:exactMatch RHEA:13233
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30947" xsd:anyURI
[Term]
id: GO:0047976
@@ -305442,6 +317271,9 @@
xref: RHEA:22796
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.102
+property_value: skos:exactMatch RHEA:22796
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047977
@@ -305458,7 +317290,10 @@
xref: Reactome:R-HSA-2161949 "HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH"
xref: RHEA:16665
is_a: GO:0004301 ! epoxide hydrolase activity
+property_value: skos:exactMatch EC:3.3.2.7
+property_value: skos:exactMatch RHEA:16665
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27074" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047978
@@ -305471,7 +317306,10 @@
xref: MetaCyc:HEXADECANOL-DEHYDROGENASE-RXN
xref: RHEA:22056
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.164
+property_value: skos:exactMatch RHEA:22056
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047979
@@ -305480,7 +317318,14 @@
def: "Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202." [EC:1.1.3.5]
synonym: "D-hexose:oxygen 1-oxidoreductase activity" RELATED [EC:1.1.3.5]
xref: EC:1.1.3.5
+xref: MetaCyc:RXN-13740
+xref: MetaCyc:RXN-13741
+xref: MetaCyc:RXN-17229
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.5
+property_value: skos:narrowMatch MetaCyc:RXN-13740
+property_value: skos:narrowMatch MetaCyc:RXN-13741
+property_value: skos:narrowMatch MetaCyc:RXN-17229
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
[Term]
@@ -305496,6 +317341,9 @@
xref: MetaCyc:HIPPURATE-HYDROLASE-RXN
xref: RHEA:10424
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.32
+property_value: skos:exactMatch RHEA:10424
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047981
@@ -305511,6 +317359,9 @@
xref: MetaCyc:HISTIDINE-N-ACETYLTRANSFERASE-RXN
xref: RHEA:24596
is_a: GO:0140085 ! L-amino-acid N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.33
+property_value: skos:exactMatch RHEA:24596
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047982
@@ -305525,6 +317376,9 @@
xref: Reactome:R-HSA-1614631 "Homocysteine is degraded to oxobutanoate and H2S"
xref: RHEA:14501
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.2
+property_value: skos:exactMatch RHEA:14501
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047983
@@ -305539,6 +317393,9 @@
xref: MetaCyc:HOMOGLUTATHIONE-SYNTHASE-RXN
xref: RHEA:17993
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.23
+property_value: skos:exactMatch RHEA:17993
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047985
@@ -305555,6 +317412,9 @@
xref: MetaCyc:HYDROGEN-DEHYDROGENASE-RXN
xref: RHEA:24636
is_a: GO:0016696 ! oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.12.1.2
+property_value: skos:exactMatch RHEA:24636
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047986
@@ -305569,6 +317429,9 @@
xref: MetaCyc:HYDROGEN-SULFIDE-S-ACETYLTRANSFERASE-RXN
xref: RHEA:16625
is_a: GO:0016418 ! S-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.10
+property_value: skos:exactMatch RHEA:16625
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047988
@@ -305582,6 +317445,8 @@
xref: Reactome:R-HSA-880002 "(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate"
xref: Reactome:R-HSA-880033 "2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde"
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.24
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047989
@@ -305595,6 +317460,9 @@
xref: MetaCyc:HYDROXYBUTYRATE-DIMER-HYDROLASE-RXN
xref: RHEA:10172
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.22
+property_value: skos:exactMatch RHEA:10172
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047990
@@ -305608,6 +317476,9 @@
xref: MetaCyc:HYDROXYGLUTAMATE-DECARBOXYLASE-RXN
xref: RHEA:14073
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.16
+property_value: skos:exactMatch RHEA:14073
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047991
@@ -305622,7 +317493,10 @@
xref: MetaCyc:RXN-13595
xref: RHEA:19969
is_a: GO:0016663 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.7.3.6
+property_value: skos:exactMatch RHEA:19969
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047992
@@ -305639,6 +317513,9 @@
xref: RHEA:19049
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019202 ! amino acid kinase activity
+property_value: skos:exactMatch EC:2.7.1.81
+property_value: skos:exactMatch RHEA:19049
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047993
@@ -305651,6 +317528,9 @@
xref: MetaCyc:HYDROXYMALONATE-DEHYDROGENASE-RXN
xref: RHEA:11284
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.167
+property_value: skos:exactMatch RHEA:11284
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047994
@@ -305668,6 +317548,9 @@
xref: MetaCyc:HYDROXYMETHYLGLUTARYL-COA-HYDROLASE-RXN
xref: RHEA:16305
is_a: GO:0016289 ! acyl-CoA hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.5
+property_value: skos:exactMatch RHEA:16305
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047995
@@ -305678,8 +317561,14 @@
synonym: "HPRP" RELATED [EC:1.1.1.237]
xref: EC:1.1.1.237
xref: MetaCyc:HYDROXYPHENYLPYRUVATE-REDUCTASE-RXN
+xref: RHEA:10776
+xref: RHEA:10780
is_a: GO:0140175 ! (2R)-2-hydroxyacid dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.237
+property_value: skos:narrowMatch RHEA:10776
+property_value: skos:narrowMatch RHEA:10780
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30138" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047996
@@ -305692,6 +317581,9 @@
xref: MetaCyc:HYDROXYPHYTANATE-OXIDASE-RXN
xref: RHEA:21680
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.27
+property_value: skos:exactMatch RHEA:21680
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047997
@@ -305705,6 +317597,9 @@
xref: MetaCyc:HYDROXYPYRUVATE-DECARBOXYLASE-RXN
xref: RHEA:20561
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.40
+property_value: skos:exactMatch RHEA:20561
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047998
@@ -305722,6 +317617,9 @@
xref: MetaCyc:HYOSCYAMINE-6-DIOXYGENASE-RXN
xref: RHEA:12629
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.11
+property_value: skos:exactMatch RHEA:12629
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0047999
@@ -305736,6 +317634,9 @@
xref: MetaCyc:HYPONITRITE-REDUCTASE-RXN
xref: RHEA:19337
is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.7.1.5
+property_value: skos:exactMatch RHEA:19337
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0048000
@@ -305748,6 +317649,9 @@
xref: MetaCyc:RXN-3762
xref: RHEA:22960
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.88
+property_value: skos:exactMatch RHEA:22960
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0048001
@@ -305766,6 +317670,9 @@
xref: MetaCyc:ERYTH4PDEHYDROG-RXN
xref: RHEA:12056
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.72
+property_value: skos:exactMatch RHEA:12056
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0048002
@@ -305936,8 +317843,8 @@
synonym: "receptor agonist activity" RELATED [GOC:molecular_function_refactoring]
synonym: "signaling molecule" BROAD []
synonym: "signaling receptor ligand activity" EXACT []
+xref: Reactome:R-HSA-163625 "Glucagon binds to Glucagon receptor"
xref: Reactome:R-HSA-381612 "GLP1R binds GLP1"
-xref: Reactome:R-HSA-8848663 "ADIPOQ trimer binds ADIPOR dimers"
is_a: GO:0005102 ! signaling receptor binding
is_a: GO:0030546 ! signaling receptor activator activity
relationship: part_of GO:0007165 ! signal transduction
@@ -306216,6 +318123,9 @@
xref: Reactome:R-HSA-8863761 "UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose"
xref: RHEA:23916
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.35
+property_value: skos:exactMatch RHEA:23916
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0048041
@@ -306786,6 +318696,7 @@
synonym: "calcium- and calmodulin-regulated cyclic-GMP phosphodiesterase activity" EXACT []
synonym: "calcium/calmodulin-regulated cGMP-specific phosphodiesterase activity" EXACT []
is_a: GO:0047555 ! 3',5'-cyclic-GMP phosphodiesterase activity
+property_value: skos:broadMatch EC:3.1.4.35
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22791" xsd:anyURI
[Term]
@@ -307813,6 +319724,9 @@
xref: Reactome:R-HSA-389639 "phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2"
xref: RHEA:16065
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.18
+property_value: skos:exactMatch RHEA:16065
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0048245
@@ -308430,6 +320344,9 @@
xref: RHEA:18041
is_a: GO:0016664 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor
is_a: GO:0098809 ! nitrite reductase activity
+property_value: skos:exactMatch EC:1.7.7.1
+property_value: skos:exactMatch RHEA:18041
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0048308
@@ -309846,6 +321763,9 @@
xref: MetaCyc:4.1.1.81-RXN
xref: RHEA:11492
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.81
+property_value: skos:exactMatch RHEA:11492
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0048473
@@ -310145,7 +322065,10 @@
xref: TC:3.A.1.19.1
is_a: GO:0015234 ! thiamine transmembrane transporter activity
is_a: GO:0140394 ! ABC-type azole transporter activity
+property_value: skos:exactMatch EC:7.6.2.15
+property_value: skos:exactMatch RHEA:29811
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0048503
@@ -310459,6 +322382,9 @@
xref: EC:1.14.13.81
xref: RHEA:33235
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.81
+property_value: skos:exactMatch RHEA:33235
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0048530
@@ -312974,15 +324900,13 @@
[Term]
id: GO:0048784
-name: pigment biosynthetic process involved in pigment granule maturation
+name: obsolete pigment biosynthetic process involved in pigment granule maturation
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state." [GOC:jid]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state." [GOC:jid]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM.
synonym: "pigment biosynthetic process during pigment granule maturation" RELATED [GOC:dph, GOC:tb]
-is_a: GO:0043324 ! pigment metabolic process involved in developmental pigmentation
-is_a: GO:0043477 ! pigment biosynthetic process involved in pigment accumulation
-intersection_of: GO:0046148 ! pigment biosynthetic process
-intersection_of: part_of GO:0048757 ! pigment granule maturation
-relationship: part_of GO:0048757 ! pigment granule maturation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31228" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0048785
@@ -314446,6 +326370,9 @@
xref: MetaCyc:D-GLUTAMINASE-RXN
xref: RHEA:22840
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.35
+property_value: skos:exactMatch RHEA:22840
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050002
@@ -314458,6 +326385,9 @@
xref: MetaCyc:1.21.4.1-RXN
xref: RHEA:12737
is_a: GO:0050485 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor
+property_value: skos:exactMatch EC:1.21.4.1
+property_value: skos:exactMatch RHEA:12737
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050003
@@ -314472,6 +326402,9 @@
xref: MetaCyc:DEOXYCYTIDYLATE-C-METHYLTRANSFERASE-RXN
xref: RHEA:11568
is_a: GO:0008169 ! C-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.54
+property_value: skos:exactMatch RHEA:11568
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050004
@@ -314487,6 +326420,9 @@
xref: MetaCyc:ISOFLAVONE-7-O-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:56344
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.170
+property_value: skos:exactMatch RHEA:56344
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050005
@@ -314504,6 +326440,9 @@
xref: RHEA:24144
xref: UM-BBD_reactionID:r1167
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.57
+property_value: skos:exactMatch RHEA:24144
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050006
@@ -314518,6 +326457,9 @@
xref: MetaCyc:ISOMALTULOSE-SYNTHASE-RXN
xref: RHEA:24032
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.11
+property_value: skos:exactMatch RHEA:24032
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050007
@@ -314531,6 +326473,9 @@
xref: MetaCyc:ISONOCARDICIN-SYNTHASE-RXN
xref: RHEA:19845
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.38
+property_value: skos:exactMatch RHEA:19845
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050008
@@ -314544,6 +326489,9 @@
xref: MetaCyc:ISOPIPERITENONE-DELTA-ISOMERASE-RXN
xref: RHEA:21516
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.11
+property_value: skos:exactMatch RHEA:21516
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050009
@@ -314556,6 +326504,9 @@
xref: MetaCyc:ISOPROPANOL-DEHYDROGENASE-NADP+-RXN
xref: RHEA:21792
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.80
+property_value: skos:exactMatch RHEA:21792
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050010
@@ -314571,6 +326522,9 @@
xref: MetaCyc:ISOVITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:19529
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.106
+property_value: skos:exactMatch RHEA:19529
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050011
@@ -314584,6 +326538,9 @@
xref: MetaCyc:ITACONYL-COA-HYDRATASE-RXN
xref: RHEA:13785
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.56
+property_value: skos:exactMatch RHEA:13785
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050012
@@ -314599,7 +326556,10 @@
xref: MetaCyc:JUGLONE-3-MONOOXYGENASE-RXN
xref: RHEA:18745
is_a: GO:0016727 ! oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor
+property_value: skos:exactMatch EC:1.17.3.4
+property_value: skos:exactMatch RHEA:18745
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050013
@@ -314613,6 +326573,9 @@
xref: MetaCyc:KETOPANTOALDOLASE-RXN
xref: RHEA:23276
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.12
+property_value: skos:exactMatch RHEA:23276
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050014
@@ -314629,6 +326592,9 @@
xref: MetaCyc:KETOTETROSE-PHOSPHATE-ALDOLASE-RXN
xref: RHEA:20932
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.2
+property_value: skos:exactMatch RHEA:20932
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050015
@@ -314643,6 +326609,9 @@
xref: MetaCyc:KIEVITONE-HYDRATASE-RXN
xref: RHEA:23604
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.95
+property_value: skos:exactMatch RHEA:23604
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050016
@@ -314658,6 +326627,9 @@
xref: RHEA:11968
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.2
+property_value: skos:exactMatch RHEA:11968
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050017
@@ -314673,6 +326645,9 @@
xref: MetaCyc:L-3-CYANOALANINE-SYNTHASE-RXN
xref: RHEA:17821
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.9
+property_value: skos:exactMatch RHEA:17821
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050018
@@ -314684,6 +326659,9 @@
xref: MetaCyc:L-AMINO-ACID-DEHYDROGENASE-RXN
xref: RHEA:10396
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.5
+property_value: skos:exactMatch RHEA:10396
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050019
@@ -314695,6 +326673,9 @@
xref: MetaCyc:L-ARABINITOL-4-DEHYDROGENASE-RXN
xref: RHEA:16381
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.12
+property_value: skos:exactMatch RHEA:16381
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050020
@@ -314710,6 +326691,9 @@
xref: MetaCyc:L-ARABINONATE-DEHYDRATASE-RXN
xref: RHEA:20968
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.25
+property_value: skos:exactMatch RHEA:20968
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050021
@@ -314722,6 +326706,9 @@
xref: MetaCyc:L-ARABINONOLACTONASE-RXN
xref: RHEA:16217
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.15
+property_value: skos:exactMatch RHEA:16217
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050022
@@ -314734,6 +326721,9 @@
xref: MetaCyc:L-ARABINOSE-1-DEHYDROGENASE-RXN
xref: RHEA:17925
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.46
+property_value: skos:exactMatch RHEA:17925
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050023
@@ -314748,6 +326738,9 @@
xref: MetaCyc:L-FUCONATE-HYDRATASE-RXN
xref: RHEA:22772
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.68
+property_value: skos:exactMatch RHEA:22772
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050024
@@ -314764,6 +326757,9 @@
xref: RHEA:20617
is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.3.3.12
+property_value: skos:exactMatch RHEA:20617
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050025
@@ -314780,6 +326776,9 @@
xref: MetaCyc:L-GLUTAMATE-OXIDASE-RXN
xref: RHEA:20728
is_a: GO:0001716 ! L-amino-acid oxidase activity
+property_value: skos:exactMatch EC:1.4.3.11
+property_value: skos:exactMatch RHEA:20728
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050026
@@ -314793,6 +326792,8 @@
xref: EC:1.1.1.185
xref: MetaCyc:L-GLYCOL-DEHYDROGENASE-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.185
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050027
@@ -314825,6 +326826,9 @@
xref: MetaCyc:L-LYSINE-LACTAMASE-RXN
xref: RHEA:21388
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.11
+property_value: skos:exactMatch RHEA:21388
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050029
@@ -314840,6 +326844,11 @@
xref: MetaCyc:L-LYSINE-OXIDASE-RXN
xref: RHEA:14437
is_a: GO:0001716 ! L-amino-acid oxidase activity
+property_value: skos:exactMatch EC:1.4.3.14
+property_value: skos:exactMatch KEGG_REACTION:R00447
+property_value: skos:exactMatch MetaCyc:L-LYSINE-OXIDASE-RXN
+property_value: skos:exactMatch RHEA:14437
+property_value: skos:relatedMatch MetaCyc:PWY-5311
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -314853,6 +326862,9 @@
xref: MetaCyc:L-PIPECOLATE-DEHYDROGENASE-RXN
xref: RHEA:19777
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.99.3
+property_value: skos:exactMatch RHEA:19777
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050031
@@ -314867,6 +326879,9 @@
xref: Reactome:R-HSA-6783880 "PIPOX oxidises PPCA to P6C"
xref: RHEA:11992
is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.5.3.7
+property_value: skos:exactMatch RHEA:11992
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050032
@@ -314880,6 +326895,9 @@
xref: MetaCyc:L-RHAMNONATE-DEHYDRATASE-RXN
xref: RHEA:23080
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.90
+property_value: skos:exactMatch RHEA:23080
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050033
@@ -314894,6 +326912,9 @@
xref: MetaCyc:L-RHAMNONO-14-LACTONASE-RXN
xref: RHEA:10288
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.65
+property_value: skos:exactMatch RHEA:10288
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050034
@@ -314906,6 +326927,9 @@
xref: MetaCyc:L-RHAMNOSE-1-DEHYDROGENASE-RXN
xref: RHEA:12649
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.173
+property_value: skos:exactMatch RHEA:12649
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050035
@@ -314918,6 +326942,9 @@
xref: MetaCyc:L-SORBOSE-OXIDASE-RXN
xref: RHEA:17853
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.11
+property_value: skos:exactMatch RHEA:17853
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050036
@@ -314932,6 +326959,9 @@
xref: MetaCyc:L-THREONATE-3-DEHYDROGENASE-RXN
xref: RHEA:23376
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.129
+property_value: skos:exactMatch RHEA:23376
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050037
@@ -314946,6 +326976,9 @@
xref: MetaCyc:L-XYLOSE-1-DEHYDROGENASE-RXN
xref: RHEA:15789
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.113
+property_value: skos:exactMatch RHEA:15789
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050038
@@ -314960,7 +326993,10 @@
xref: Reactome:R-HSA-5662851 "Defective DCXR does not reduce L-xylulose to xylitol"
xref: RHEA:17025
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.10
+property_value: skos:exactMatch RHEA:17025
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050039
@@ -314977,6 +327013,9 @@
xref: MetaCyc:RXN-15744
xref: RHEA:15885
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.55
+property_value: skos:exactMatch RHEA:15885
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050040
@@ -314997,7 +327036,10 @@
xref: MetaCyc:RXN-19631
xref: RHEA:16513
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
+property_value: skos:exactMatch EC:1.13.12.4
+property_value: skos:exactMatch RHEA:16513
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050041
@@ -315012,6 +327054,9 @@
xref: MetaCyc:LACTATE-ALDOLASE-RXN
xref: RHEA:17909
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.36
+property_value: skos:exactMatch RHEA:17909
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050042
@@ -315025,6 +327070,9 @@
xref: MetaCyc:LACTATE-MALATE-TRANSHYDROGENASE-RXN
xref: RHEA:10984
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.7
+property_value: skos:exactMatch RHEA:10984
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050043
@@ -315039,6 +327087,9 @@
xref: MetaCyc:LACTATE-RACEMASE-RXN
xref: RHEA:10960
is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives
+property_value: skos:exactMatch EC:5.1.2.1
+property_value: skos:exactMatch RHEA:10960
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050044
@@ -315052,6 +327103,9 @@
xref: MetaCyc:LACTOSE-6-PHOSPHATE-ISOMERASE-RXN
xref: RHEA:13033
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.26
+property_value: skos:exactMatch RHEA:13033
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050045
@@ -315063,6 +327117,9 @@
xref: MetaCyc:LAMINARIBIOSE-PHOSPHORYLASE-RXN
xref: RHEA:16617
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.31
+property_value: skos:exactMatch RHEA:16617
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050046
@@ -315077,8 +327134,13 @@
synonym: "lathosterol oxidase activity" EXACT []
xref: EC:1.14.19.20
xref: MetaCyc:RXN-16378
+xref: MetaCyc:RXN-4209
xref: RHEA:54320
is_a: GO:0070704 ! sterol desaturase activity
+property_value: skos:exactMatch EC:1.14.19.20
+property_value: skos:exactMatch MetaCyc:RXN-16378
+property_value: skos:exactMatch RHEA:54320
+property_value: skos:narrowMatch MetaCyc:RXN-4209
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21133" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27381" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
@@ -315096,6 +327158,9 @@
xref: MetaCyc:LEUCINE-23-AMINOMUTASE-RXN
xref: RHEA:10284
is_a: GO:0016869 ! intramolecular aminotransferase activity
+property_value: skos:exactMatch EC:5.4.3.7
+property_value: skos:exactMatch RHEA:10284
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050048
@@ -315121,6 +327186,9 @@
xref: MetaCyc:LEUCINE-DEHYDROGENASE-RXN
xref: RHEA:12220
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.9
+property_value: skos:exactMatch RHEA:12220
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050050
@@ -315134,6 +327202,9 @@
xref: MetaCyc:LEUCINE-N-ACETYLTRANSFERASE-RXN
xref: RHEA:20089
is_a: GO:0140085 ! L-amino-acid N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.66
+property_value: skos:exactMatch RHEA:20089
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050051
@@ -315152,6 +327223,9 @@
xref: RHEA:22176
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
relationship: part_of GO:0036101 ! leukotriene B4 catabolic process
+property_value: skos:exactMatch EC:1.14.14.94
+property_value: skos:exactMatch RHEA:22176
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050052
@@ -315167,6 +327241,9 @@
xref: MetaCyc:LEUKOTRIENE-E4-20-MONOOXYGENASE-RXN
xref: RHEA:24120
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.34
+property_value: skos:exactMatch RHEA:24120
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050053
@@ -315182,6 +327259,9 @@
xref: MetaCyc:LEVANSUCRASE-RXN
xref: RHEA:13653
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.10
+property_value: skos:exactMatch RHEA:13653
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050054
@@ -315196,6 +327276,9 @@
xref: MetaCyc:LIGNOSTILBENE-ALPHA-BETA-DIOXYGENASE-RXN
xref: RHEA:21340
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.43
+property_value: skos:exactMatch RHEA:21340
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050055
@@ -315209,6 +327292,9 @@
xref: MetaCyc:LIMONIN-D-RING-LACTONASE-RXN
xref: RHEA:10896
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.36
+property_value: skos:exactMatch RHEA:10896
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050056
@@ -315221,6 +327307,9 @@
xref: MetaCyc:LINALOOL-8-MONOOXYGENASE-RXN
xref: RHEA:32635
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.84
+property_value: skos:exactMatch RHEA:32635
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050057
@@ -315239,6 +327328,9 @@
xref: RHEA:20009
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.63
+property_value: skos:exactMatch RHEA:20009
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050058
@@ -315252,6 +327344,9 @@
xref: MetaCyc:LINOLEATE-ISOMERASE-RXN
xref: RHEA:17381
is_a: GO:0016859 ! cis-trans isomerase activity
+property_value: skos:exactMatch EC:5.2.1.5
+property_value: skos:exactMatch RHEA:17381
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050059
@@ -315264,6 +327359,9 @@
xref: RHEA:23292
is_a: GO:0016301 ! kinase activity
is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor
+property_value: skos:exactMatch EC:2.7.3.5
+property_value: skos:exactMatch RHEA:23292
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050060
@@ -315277,6 +327375,9 @@
xref: MetaCyc:LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN
xref: RHEA:17977
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.192
+property_value: skos:exactMatch RHEA:17977
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050061
@@ -315293,7 +327394,10 @@
xref: RHEA:10652
xref: UM-BBD_reactionID:r1404
is_a: GO:0102673 ! fatty aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.48
+property_value: skos:exactMatch RHEA:10652
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28142" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050062
@@ -315309,6 +327413,8 @@
xref: MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN
xref: RHEA:15437
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.50
+property_value: skos:exactMatch RHEA:15437
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25060" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25804" xsd:anyURI
@@ -315337,6 +327443,9 @@
xref: MetaCyc:LUTEOLIN-7-O-GLUCORONOSYLTRANSFERASE-RXN
xref: RHEA:10568
is_a: GO:0015020 ! glucuronosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.189
+property_value: skos:exactMatch RHEA:10568
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050065
@@ -315353,6 +327462,11 @@
xref: MetaCyc:LYSINE--PYRUVATE-6-AMINOTRANSFERASE-RXN
xref: RHEA:19393
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.71
+property_value: skos:exactMatch KEGG_REACTION:R00453
+property_value: skos:exactMatch MetaCyc:LYSINE--PYRUVATE-6-AMINOTRANSFERASE-RXN
+property_value: skos:exactMatch RHEA:19393
+property_value: skos:relatedMatch MetaCyc:PWY-5324
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -315366,6 +327480,9 @@
xref: MetaCyc:LYSINE-23-AMINOMUTASE-RXN
xref: RHEA:19177
is_a: GO:0016869 ! intramolecular aminotransferase activity
+property_value: skos:exactMatch EC:5.4.3.2
+property_value: skos:exactMatch RHEA:19177
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050067
@@ -315381,6 +327498,9 @@
xref: MetaCyc:LYSINE-2-MONOOXYGENASE-RXN
xref: RHEA:14601
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
+property_value: skos:exactMatch EC:1.13.12.2
+property_value: skos:exactMatch RHEA:14601
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050068
@@ -315394,6 +327514,9 @@
xref: MetaCyc:LYSINE-CARBAMOYLTRANSFERASE-RXN
xref: RHEA:17121
is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity
+property_value: skos:exactMatch EC:2.1.3.8
+property_value: skos:exactMatch RHEA:17121
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050069
@@ -315405,6 +327528,9 @@
xref: MetaCyc:LYSINE-DEHYDROGENASE-RXN
xref: RHEA:18505
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.15
+property_value: skos:exactMatch RHEA:18505
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050070
@@ -315418,6 +327544,9 @@
xref: MetaCyc:LYSOLECITHIN-ACYLMUTASE-RXN
xref: RHEA:24356
is_a: GO:0016867 ! intramolecular acyltransferase activity
+property_value: skos:exactMatch EC:5.4.1.1
+property_value: skos:exactMatch RHEA:24356
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050071
@@ -315430,7 +327559,10 @@
xref: MetaCyc:LYSYLTRANSFERASE-RXN
xref: RHEA:10668
is_a: GO:0016755 ! aminoacyltransferase activity
+property_value: skos:exactMatch EC:2.3.2.3
+property_value: skos:exactMatch RHEA:10668
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050072
@@ -315456,6 +327588,9 @@
xref: RHEA:18333
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.136
+property_value: skos:exactMatch RHEA:18333
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050074
@@ -315470,6 +327605,9 @@
xref: MetaCyc:MALATE--COA-LIGASE-RXN
xref: RHEA:26193
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.9
+property_value: skos:exactMatch RHEA:26193
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050075
@@ -315485,6 +327623,9 @@
xref: MetaCyc:MALEATE-HYDRATASE-RXN
xref: RHEA:23692
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.31
+property_value: skos:exactMatch RHEA:23692
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050076
@@ -315497,6 +327638,9 @@
xref: MetaCyc:MALEATE-ISOMERASE-RXN
xref: RHEA:13169
is_a: GO:0016859 ! cis-trans isomerase activity
+property_value: skos:exactMatch EC:5.2.1.1
+property_value: skos:exactMatch RHEA:13169
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050077
@@ -315508,6 +327652,9 @@
xref: MetaCyc:MALEYLPYRUVATE-ISOMERASE-RXN
xref: RHEA:17393
is_a: GO:0016859 ! cis-trans isomerase activity
+property_value: skos:exactMatch EC:5.2.1.4
+property_value: skos:exactMatch RHEA:17393
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050078
@@ -315521,6 +327668,9 @@
xref: MetaCyc:MALONATE-COA-TRANSFERASE-RXN
xref: RHEA:18817
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.3
+property_value: skos:exactMatch RHEA:18817
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050079
@@ -315540,6 +327690,9 @@
xref: MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDRATASE-RXN
xref: RHEA:17957
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.27
+property_value: skos:exactMatch MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDRATASE-RXN
+property_value: skos:exactMatch RHEA:17957
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -315556,6 +327709,9 @@
xref: Reactome:R-HSA-977317 "malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome"
xref: RHEA:18781
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.9
+property_value: skos:exactMatch RHEA:18781
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050081
@@ -315568,6 +327724,9 @@
xref: MetaCyc:MALTOSE-6-PHOSPHATE-GLUCOSIDASE-RXN
xref: RHEA:20421
is_a: GO:0015926 ! glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.122
+property_value: skos:exactMatch RHEA:20421
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050082
@@ -315579,6 +327738,9 @@
xref: MetaCyc:MALTOSE-PHOSPHORYLASE-RXN
xref: RHEA:21116
is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity
+property_value: skos:exactMatch EC:2.4.1.8
+property_value: skos:exactMatch RHEA:21116
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050083
@@ -315591,7 +327753,10 @@
xref: MetaCyc:MALYL-COA-LYASE-RXN
xref: RHEA:16629
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:broadMatch EC:4.1.3.24
+property_value: skos:exactMatch RHEA:16629
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050084
@@ -315605,6 +327770,9 @@
xref: MetaCyc:MANNITOL-1-PHOSPHATASE-RXN
xref: RHEA:19537
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.22
+property_value: skos:exactMatch RHEA:19537
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050085
@@ -315618,6 +327786,9 @@
xref: MetaCyc:MANNITOL-2-DEHYDROGENASE-NADP+-RXN
xref: RHEA:16765
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.138
+property_value: skos:exactMatch RHEA:16765
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050086
@@ -315630,6 +327801,9 @@
xref: MetaCyc:MANNITOL-2-DEHYDROGENASE-RXN
xref: RHEA:12084
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.67
+property_value: skos:exactMatch RHEA:12084
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050087
@@ -315642,6 +327816,9 @@
xref: MetaCyc:MANNITOL-DEHYDROGENASE-CYTOCHROME-RXN
xref: RHEA:17597
is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.1.2.2
+property_value: skos:exactMatch RHEA:17597
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050088
@@ -315660,6 +327837,9 @@
xref: MetaCyc:MANNOSE-6-PHOSPHATE-6-REDUCTASE-RXN
xref: RHEA:14925
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.224
+property_value: skos:exactMatch RHEA:14925
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050089
@@ -315674,6 +327854,9 @@
xref: MetaCyc:MANNOSE-ISOMERASE-RXN
xref: RHEA:22604
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.7
+property_value: skos:exactMatch RHEA:22604
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050090
@@ -315688,6 +327871,8 @@
xref: EC:1.1.1.131
xref: MetaCyc:MANNURONATE-REDUCTASE-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.131
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050091
@@ -315704,6 +327889,9 @@
xref: MetaCyc:MELILOTATE-3-MONOOXYGENASE-RXN
xref: RHEA:17669
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.4
+property_value: skos:exactMatch RHEA:17669
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050092
@@ -315716,6 +327904,9 @@
xref: MetaCyc:MESO-TARTRATE-DEHYDROGENASE-RXN
xref: RHEA:18553
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.7
+property_value: skos:exactMatch RHEA:18553
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050093
@@ -315729,7 +327920,10 @@
xref: MetaCyc:METHANOL-DEHYDROGENASE-RXN
xref: RHEA:19401
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.244
+property_value: skos:exactMatch RHEA:19401
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050094
@@ -315744,6 +327938,9 @@
xref: MetaCyc:METHIONINE--GLYOXYLATE-TRANSAMINASE-RXN
xref: RHEA:22884
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.73
+property_value: skos:exactMatch RHEA:22884
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050095
@@ -315758,6 +327955,9 @@
xref: MetaCyc:METHIONINE-DECARBOXYLASE-RXN
xref: RHEA:17757
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.57
+property_value: skos:exactMatch RHEA:17757
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050096
@@ -315773,6 +327973,9 @@
xref: MetaCyc:METHYLASPARTATE-AMMONIA-LYASE-RXN
xref: RHEA:12829
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.2
+property_value: skos:exactMatch RHEA:12829
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050097
@@ -315794,6 +327997,9 @@
xref: MetaCyc:METHYLASPARTATE-MUTASE-RXN
xref: RHEA:12857
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.1
+property_value: skos:exactMatch RHEA:12857
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050098
@@ -315807,6 +328013,9 @@
xref: MetaCyc:METHYLGUANIDINASE-RXN
xref: RHEA:11764
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.16
+property_value: skos:exactMatch RHEA:11764
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050099
@@ -315821,6 +328030,9 @@
xref: MetaCyc:METHYLGUTAMATE-DEHYDROGENASE-RXN
xref: RHEA:22572
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.99.5
+property_value: skos:exactMatch RHEA:22572
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050100
@@ -315835,6 +328047,9 @@
xref: MetaCyc:METHYLITACONATE-DELTA-ISOMERASE-RXN
xref: RHEA:23480
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.6
+property_value: skos:exactMatch RHEA:23480
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050101
@@ -315847,7 +328062,10 @@
xref: MetaCyc:MIMOSINASE-RXN
xref: RHEA:75355
is_a: GO:0016843 ! amine-lyase activity
+property_value: skos:exactMatch EC:4.3.3.8
+property_value: skos:exactMatch RHEA:75355
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24852" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050102
@@ -315860,6 +328078,9 @@
xref: MetaCyc:CELLODEXTRIN-PHOSPHORYLASE-RXN
xref: RHEA:23024
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.49
+property_value: skos:exactMatch RHEA:23024
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050103
@@ -315873,6 +328094,9 @@
xref: MetaCyc:DEXTRIN-DEXTRANASE-RXN
xref: RHEA:14625
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.2
+property_value: skos:exactMatch RHEA:14625
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050104
@@ -315892,6 +328116,9 @@
xref: Reactome:R-HSA-5661290 "CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate"
xref: RHEA:12889
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.45
+property_value: skos:exactMatch RHEA:12889
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050105
@@ -315907,6 +328134,9 @@
xref: MetaCyc:L-GULONOLACTONE-OXIDASE-RXN
xref: RHEA:32363
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.8
+property_value: skos:exactMatch RHEA:32363
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050106
@@ -315920,6 +328150,9 @@
xref: MetaCyc:MONOMETHYL-SULFATASE-RXN
xref: RHEA:14221
is_a: GO:0008484 ! sulfuric ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.6.16
+property_value: skos:exactMatch RHEA:14221
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050107
@@ -315931,6 +328164,8 @@
xref: EC:2.3.1.69
xref: MetaCyc:MONOTERPENOL-O-ACETYLTRANSFERASE-RXN
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.69
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050108
@@ -315944,6 +328179,8 @@
xref: MetaCyc:MONOTERPENYL-PYROPHOSPHATASE-RXN
xref: RHEA:81371
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:broadMatch EC:3.1.7.3
+property_value: skos:exactMatch RHEA:81371
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27990" xsd:anyURI
[Term]
@@ -315957,6 +328194,8 @@
xref: EC:1.1.1.218
xref: MetaCyc:MORPHINE-6-DEHYDROGENASE-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.218
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050110
@@ -315980,6 +328219,9 @@
xref: MetaCyc:MYCOCEROSATE-SYNTHASE-RXN
xref: RHEA:10588
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.111
+property_value: skos:exactMatch RHEA:10588
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050112
@@ -315994,7 +328236,10 @@
xref: MetaCyc:MYO-INOSITOL-2-DEHYDROGENASE-RXN
xref: RHEA:16949
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.18
+property_value: skos:exactMatch RHEA:16949
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050113
@@ -316012,6 +328257,9 @@
xref: RHEA:23696
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
+property_value: skos:exactMatch EC:1.13.99.1
+property_value: skos:exactMatch RHEA:23696
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050114
@@ -316027,6 +328275,9 @@
xref: MetaCyc:MYO-INOSOSE-2-DEHYDRATASE-RXN
xref: RHEA:14065
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.44
+property_value: skos:exactMatch RHEA:14065
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050115
@@ -316043,6 +328294,8 @@
xref: MetaCyc:MYOSIN-LIGHT-CHAIN-PHOSPHATASE-RXN
xref: Reactome:R-HSA-419232 "Myosin phosphatase dephosphorylates myosin regulatory light chain"
is_a: GO:0004721 ! phosphoprotein phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.53
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050116
@@ -316057,6 +328310,9 @@
xref: MetaCyc:NN-DIMETHYLFORMAMIDASE-RXN
xref: RHEA:19517
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.56
+property_value: skos:exactMatch RHEA:19517
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050117
@@ -316070,6 +328326,9 @@
xref: RHEA:23212
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0019213 ! deacetylase activity
+property_value: skos:exactMatch EC:3.5.1.21
+property_value: skos:exactMatch RHEA:23212
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050118
@@ -316086,6 +328345,8 @@
xref: RHEA:20405
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0019213 ! deacetylase activity
+property_value: skos:exactMatch EC:3.5.1.47
+property_value: skos:exactMatch RHEA:20405
[Term]
id: GO:0050119
@@ -316102,6 +328363,9 @@
xref: RHEA:20593
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0019213 ! deacetylase activity
+property_value: skos:exactMatch EC:3.5.1.33
+property_value: skos:exactMatch RHEA:20593
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050120
@@ -316116,6 +328380,9 @@
xref: MetaCyc:N-ACETYLHEXOSAMINE-1-DEHYDROGENASE-RXN
xref: RHEA:23144
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.240
+property_value: skos:exactMatch RHEA:23144
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050121
@@ -316132,6 +328399,9 @@
xref: Reactome:R-HSA-6803761 "RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc"
xref: RHEA:19033
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.8
+property_value: skos:exactMatch RHEA:19033
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050122
@@ -316146,6 +328416,9 @@
xref: MetaCyc:N-ACYLHEXOSAMINE-OXIDASE-RXN
xref: RHEA:13029
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.29
+property_value: skos:exactMatch RHEA:13029
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050123
@@ -316161,6 +328434,9 @@
xref: MetaCyc:N-ACYLMANNOSAMINE-1-DEHYDROGENASE-RXN
xref: RHEA:11540
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.233
+property_value: skos:exactMatch RHEA:11540
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050124
@@ -316176,6 +328452,9 @@
xref: Reactome:R-HSA-4084989 "NANP dephosphorylates Neu5Ac-9-P to Neu5Ac"
xref: RHEA:13057
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.29
+property_value: skos:exactMatch RHEA:13057
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050125
@@ -316192,6 +328471,9 @@
xref: MetaCyc:N-BENZYLOXYCARBONYLGLYCINE-HYDROLASE-RXN
xref: RHEA:20900
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.58
+property_value: skos:exactMatch RHEA:20900
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050126
@@ -316206,6 +328488,9 @@
xref: MetaCyc:N-CARBAMOYLPUTRESCINE-AMIDASE-RXN
xref: RHEA:22284
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.53
+property_value: skos:exactMatch RHEA:22284
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050127
@@ -316220,6 +328505,9 @@
xref: MetaCyc:N-CARBAMOYLSARCOSINE-AMIDASE-RXN
xref: RHEA:20057
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.59
+property_value: skos:exactMatch RHEA:20057
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050128
@@ -316233,6 +328521,9 @@
xref: MetaCyc:N-FERULOYLGLYCINE-DEACYLASE-RXN
xref: RHEA:10484
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.71
+property_value: skos:exactMatch RHEA:10484
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050129
@@ -316252,6 +328543,9 @@
xref: MetaCyc:N-FORMYLGLUTAMATE-DEFORMYLASE-RXN
xref: RHEA:12476
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.68
+property_value: skos:exactMatch RHEA:12476
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050130
@@ -316265,6 +328559,9 @@
xref: MetaCyc:N-METHYL-2-OXOGLUTARAMATE-HYDROLASE-RXN
xref: RHEA:24108
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.36
+property_value: skos:exactMatch RHEA:24108
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050131
@@ -316277,6 +328574,9 @@
xref: MetaCyc:N-METHYL-L-AMINO-ACID-OXIDASE-RXN
xref: RHEA:11472
is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.5.3.2
+property_value: skos:exactMatch RHEA:11472
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050132
@@ -316289,6 +328589,9 @@
xref: MetaCyc:N-METHYLALANINE-DEHYDROGENASE-RXN
xref: RHEA:21768
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.17
+property_value: skos:exactMatch RHEA:21768
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050133
@@ -316305,6 +328608,9 @@
xref: MetaCyc:N6-HYDROXYLYSINE-O-ACETYLTRANSFERASE-RXN
xref: RHEA:22388
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.102
+property_value: skos:exactMatch RHEA:22388
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050134
@@ -316323,6 +328629,9 @@
xref: MetaCyc:N6-METHYL-LYSINE-OXIDASE-RXN
xref: RHEA:23200
is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.5.3.4
+property_value: skos:exactMatch RHEA:23200
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050135
@@ -316336,6 +328645,7 @@
synonym: "NADPase activity" RELATED []
xref: RHEA:19849
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch RHEA:19849
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26011" xsd:anyURI
[Term]
@@ -316350,6 +328660,8 @@
xref: RHEA:46160
is_a: GO:0003954 ! NADH dehydrogenase activity
is_a: GO:0003955 ! NAD(P)H dehydrogenase (quinone) activity
+property_value: skos:exactMatch EC:1.6.5.9
+property_value: skos:exactMatch RHEA:46160
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25784" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30272" xsd:anyURI
@@ -316370,6 +328682,9 @@
xref: MetaCyc:NADPH-PEROXIDASE-RXN
xref: RHEA:15173
is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch EC:1.11.1.2
+property_value: skos:exactMatch RHEA:15173
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050138
@@ -316384,7 +328699,10 @@
xref: MetaCyc:RXN-7637
xref: RHEA:12236
is_a: GO:0016726 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.17.1.5
+property_value: skos:exactMatch RHEA:12236
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050139
@@ -316401,6 +328719,9 @@
xref: MetaCyc:NICOTINATE-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:19437
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.196
+property_value: skos:exactMatch RHEA:19437
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050140
@@ -316414,6 +328735,8 @@
xref: RHEA:12909
is_a: GO:0008940 ! nitrate reductase activity
is_a: GO:0016677 ! oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor
+property_value: skos:exactMatch EC:1.9.6.1
+property_value: skos:exactMatch RHEA:12909
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25967" xsd:anyURI
[Term]
@@ -316437,7 +328760,10 @@
xref: RHEA:15645
is_a: GO:0016738 ! oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor
relationship: part_of GO:0009399 ! nitrogen fixation
+property_value: skos:exactMatch EC:1.19.6.1
+property_value: skos:exactMatch RHEA:15645
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27215" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050143
@@ -316449,7 +328775,11 @@
xref: KEGG_REACTION:R03073
xref: MetaCyc:NOCARDICIN-A-EPIMERASE-RXN
xref: RHEA:22792
+xref: RHEA:42132
is_a: GO:0016855 ! racemase and epimerase activity, acting on amino acids and derivatives
+property_value: skos:exactMatch EC:5.1.1.14
+property_value: skos:exactMatch RHEA:22792
+property_value: skos:narrowMatch RHEA:42132
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
[Term]
@@ -316469,6 +328799,8 @@
xref: EC:2.4.2.6
xref: MetaCyc:NUCLEOSIDE-DEOXYRIBOSYLTRANSFERASE-RXN
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.6
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050145
@@ -316494,7 +328826,10 @@
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
is_a: GO:0019205 ! nucleobase-containing compound kinase activity
relationship: part_of GO:0046940 ! nucleoside monophosphate phosphorylation
+property_value: skos:exactMatch EC:2.7.4.4
+property_value: skos:exactMatch RHEA:24036
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29533" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050146
@@ -316512,6 +328847,9 @@
xref: RHEA:19961
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0019205 ! nucleobase-containing compound kinase activity
+property_value: skos:exactMatch EC:2.7.1.77
+property_value: skos:exactMatch RHEA:19961
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050147
@@ -316523,6 +328861,8 @@
xref: EC:2.4.2.5
xref: MetaCyc:NUCLEOSIDE-RIBOSYLTRANSFERASE-RXN
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.5
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050148
@@ -316538,6 +328878,9 @@
xref: MetaCyc:NUCLEOTIDE-PYROPHOSPHOKINASE-RXN
xref: RHEA:12713
is_a: GO:0016778 ! diphosphotransferase activity
+property_value: skos:exactMatch EC:2.7.6.4
+property_value: skos:exactMatch RHEA:12713
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050149
@@ -316553,6 +328896,9 @@
xref: MetaCyc:O-AMINOPHENOL-OXIDASE-RXN
xref: RHEA:40963
is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.10.3.4
+property_value: skos:exactMatch RHEA:40963
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050150
@@ -316571,6 +328917,9 @@
xref: RHEA:21492
xref: UM-BBD_reactionID:r0579
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.46
+property_value: skos:exactMatch RHEA:21492
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050151
@@ -316584,19 +328933,28 @@
xref: MetaCyc:OLEATE-HYDRATASE-RXN
xref: RHEA:21852
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.53
+property_value: skos:exactMatch RHEA:21852
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050152
name: omega-amidase activity
namespace: molecular_function
-def: "Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3." [EC:3.5.1.3, MetaCyc:OMEGA-AMIDASE-RXN]
+def: "Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH4+. Substrates include 2-oxosuccinamate and 2-oxoglutaramate, which get converted to oxaloacetate and 2-oxoglutarate, respectively." [RHEA:11716]
synonym: "alpha-keto acid-omega-amidase activity" RELATED [EC:3.5.1.3]
synonym: "omega-amidodicarboxylate amidohydrolase activity" RELATED [EC:3.5.1.3]
synonym: "w-amidase activity" EXACT []
xref: EC:3.5.1.3
xref: MetaCyc:OMEGA-AMIDASE-RXN
xref: RHEA:11716
+xref: RHEA:59412
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.3
+property_value: skos:exactMatch RHEA:11716
+property_value: skos:narrowMatch RHEA:59412
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30663" xsd:anyURI
[Term]
id: GO:0050153
@@ -316610,6 +328968,9 @@
xref: MetaCyc:OMEGA-HYDROXYDECANOATE-DEHYDROGENASE-RXN
xref: RHEA:20880
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.66
+property_value: skos:exactMatch RHEA:20880
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050154
@@ -316623,6 +328984,9 @@
xref: RHEA:17553
is_a: GO:0016301 ! kinase activity
is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor
+property_value: skos:exactMatch EC:2.7.3.7
+property_value: skos:exactMatch RHEA:17553
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050155
@@ -316650,6 +329014,9 @@
xref: MetaCyc:ORNITHINE-N-BENZOYLTRANSFERASE-RXN
xref: RHEA:16929
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.127
+property_value: skos:exactMatch RHEA:16929
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050157
@@ -316660,6 +329027,9 @@
xref: MetaCyc:ORNITHINE-RACEMASE-RXN
xref: RHEA:11584
is_a: GO:0047661 ! amino-acid racemase activity
+property_value: skos:exactMatch EC:5.1.1.12
+property_value: skos:exactMatch RHEA:11584
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050158
@@ -316677,8 +329047,11 @@
xref: RHEA:14861
is_a: GO:0004152 ! dihydroorotate dehydrogenase activity
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.15
+property_value: skos:exactMatch RHEA:14861
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23786" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050159
@@ -316692,6 +329065,9 @@
xref: MetaCyc:ORSELLINATE-DECARBOXYLASE-RXN
xref: RHEA:16733
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.58
+property_value: skos:exactMatch RHEA:16733
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050160
@@ -316704,21 +329080,26 @@
xref: MetaCyc:ORSELLINATE-DEPSIDE-HYDROLASE-RXN
xref: RHEA:19549
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.40
+property_value: skos:exactMatch RHEA:19549
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050161
-name: succinyl-CoA:oxalate CoA-transferase
+name: succinyl-CoA:oxalate CoA-transferase activity
namespace: molecular_function
-def: "Catalysis of the reaction: oxalate + succinyl-CoA = oxalyl-CoA + succinate." [EC:2.8.3.2, RHEA:23588]
+def: "Catalysis of the reaction: oxalate + succinyl-CoA = oxalyl-CoA + succinate." [RHEA:23588]
synonym: "oxalate CoA-transferase activity" RELATED [EC:2.8.3.2]
synonym: "oxalate coenzyme A-transferase activity" RELATED [EC:2.8.3.2]
synonym: "succinyl-beta-ketoacyl-CoA transferase activity" RELATED [EC:2.8.3.2]
-synonym: "succinyl-CoA:oxalate CoA-transferase activity" RELATED [EC:2.8.3.2]
xref: EC:2.8.3.2
xref: KEGG_REACTION:R01559
xref: MetaCyc:OXALATE-COA-TRANSFERASE-RXN
xref: RHEA:23588
is_a: GO:0008410 ! CoA-transferase activity
+property_value: skos:exactMatch EC:2.8.3.2
+property_value: skos:exactMatch RHEA:23588
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050162
@@ -316733,6 +329114,9 @@
xref: MetaCyc:OXALATE-OXIDASE-RXN
xref: RHEA:21880
is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.2.3.4
+property_value: skos:exactMatch RHEA:21880
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050163
@@ -316747,6 +329131,9 @@
xref: MetaCyc:OXALOACETATE-TAUTOMERASE-RXN
xref: RHEA:16021
is_a: GO:0016862 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups
+property_value: skos:exactMatch EC:5.3.2.2
+property_value: skos:exactMatch RHEA:16021
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050164
@@ -316769,6 +329156,9 @@
xref: RHEA:22472
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.34
+property_value: skos:exactMatch RHEA:22472
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050166
@@ -316784,6 +329174,9 @@
xref: MetaCyc:PANTOATE-4-DEHYDROGENASE-RXN
xref: RHEA:23000
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.106
+property_value: skos:exactMatch RHEA:23000
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050167
@@ -316799,6 +329192,9 @@
xref: MetaCyc:PANTOTHENOYLCYSTEINE-DECARBOXYLASE-RXN
xref: RHEA:15077
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.30
+property_value: skos:exactMatch RHEA:15077
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050168
@@ -316812,6 +329208,9 @@
xref: MetaCyc:PENTANAMIDASE-RXN
xref: RHEA:10000
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.50
+property_value: skos:exactMatch RHEA:10000
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050169
@@ -316835,6 +329234,9 @@
xref: MetaCyc:PEPTIDYL-GLUTAMINASE-RXN
xref: RHEA:10032
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.43
+property_value: skos:exactMatch RHEA:10032
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050171
@@ -316852,6 +329254,8 @@
xref: EC:2.4.1.35
xref: MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.35
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050172
@@ -316868,6 +329272,9 @@
xref: MetaCyc:PHENYLALANINE-2-MONOOXYGENASE-RXN
xref: RHEA:10712
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
+property_value: skos:exactMatch EC:1.13.12.9
+property_value: skos:exactMatch RHEA:10712
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050173
@@ -316894,6 +329301,9 @@
xref: MetaCyc:PHENYLALANINE-DECARBOXYLASE-RXN
xref: RHEA:19717
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.53
+property_value: skos:exactMatch RHEA:19717
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050175
@@ -316908,6 +329318,9 @@
xref: MetaCyc:PHENYLALANINE-DEHYDROGENASE-RXN
xref: RHEA:21408
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.20
+property_value: skos:exactMatch RHEA:21408
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050176
@@ -316922,6 +329335,9 @@
xref: MetaCyc:PHENYLALANINE-N-ACETYLTRANSFERASE-RXN
xref: RHEA:17801
is_a: GO:0140085 ! L-amino-acid N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.53
+property_value: skos:exactMatch RHEA:17801
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050177
@@ -316934,6 +329350,9 @@
xref: MetaCyc:PHENYLPYRUVATE-DECARBOXYLASE-RXN
xref: RHEA:14185
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.43
+property_value: skos:exactMatch RHEA:14185
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050178
@@ -316947,6 +329366,9 @@
xref: MetaCyc:PHENYLPYRUVATE-TAUTOMERASE-RXN
xref: RHEA:17097
is_a: GO:0016862 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups
+property_value: skos:exactMatch EC:5.3.2.1
+property_value: skos:exactMatch RHEA:17097
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050179
@@ -316960,6 +329382,9 @@
xref: MetaCyc:PHENYLSERINE-ALDOLASE-RXN
xref: RHEA:21712
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.26
+property_value: skos:exactMatch RHEA:21712
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050180
@@ -316972,7 +329397,10 @@
xref: KEGG_REACTION:R02901
xref: MetaCyc:PHLORETIN-HYDROLASE-RXN
xref: RHEA:23396
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.4
+property_value: skos:exactMatch RHEA:23396
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050181
@@ -316988,6 +329416,9 @@
xref: MetaCyc:PHORBOL-DIESTER-HYDROLASE-RXN
xref: RHEA:21316
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.51
+property_value: skos:exactMatch RHEA:21316
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050182
@@ -317001,6 +329432,9 @@
xref: MetaCyc:PHOSPHATE-BUTYRYLTRANSFERASE-RXN
xref: RHEA:20892
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.19
+property_value: skos:exactMatch RHEA:20892
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050183
@@ -317018,6 +329452,8 @@
xref: MetaCyc:PHOSPHATIDYLCHOLINE-12-MONOOXYGENASE-RXN
xref: RHEA:46360
is_a: GO:0016716 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.18.4
+property_value: skos:exactMatch RHEA:46360
[Term]
id: GO:0050184
@@ -317042,9 +329478,28 @@
synonym: "phosphatidylcholine desaturase activity" RELATED [EC:1.14.19.22]
xref: EC:1.14.19.22
xref: KEGG_REACTION:R03475
+xref: MetaCyc:PHOSPHATIDYLCHOLINE-DESATURASE-RXN
+xref: MetaCyc:RXN-8320
+xref: MetaCyc:RXN-8322
+xref: MetaCyc:RXN-8324
+xref: MetaCyc:RXN-8327
+xref: MetaCyc:RXN-8328
+xref: MetaCyc:RXN-8330
+xref: MetaCyc:RXN-8360
xref: MetaCyc:RXN-9669
xref: RHEA:46332
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.22
+property_value: skos:exactMatch MetaCyc:RXN-9669
+property_value: skos:exactMatch RHEA:46332
+property_value: skos:narrowMatch MetaCyc:PHOSPHATIDYLCHOLINE-DESATURASE-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-8320
+property_value: skos:narrowMatch MetaCyc:RXN-8322
+property_value: skos:narrowMatch MetaCyc:RXN-8324
+property_value: skos:narrowMatch MetaCyc:RXN-8327
+property_value: skos:narrowMatch MetaCyc:RXN-8328
+property_value: skos:narrowMatch MetaCyc:RXN-8330
+property_value: skos:narrowMatch MetaCyc:RXN-8360
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23540" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -317061,6 +329516,9 @@
xref: MetaCyc:PHOSPHATIDYLINOSITOL-DEACYLASE-RXN
xref: RHEA:18001
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.52
+property_value: skos:exactMatch RHEA:18001
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050186
@@ -317076,6 +329534,9 @@
xref: MetaCyc:PHOSPHOADENYLYLSULFATASE-RXN
xref: RHEA:11232
is_a: GO:0016819 ! hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides
+property_value: skos:exactMatch EC:3.6.2.2
+property_value: skos:exactMatch RHEA:11232
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050187
@@ -317088,7 +329549,10 @@
xref: KEGG_REACTION:R01882
xref: MetaCyc:PHOSPHOAMIDASE-RXN
xref: RHEA:12977
-is_a: GO:0016825 ! hydrolase activity, acting on acid phosphorus-nitrogen bonds
+is_a: GO:0016825 ! hydrolase activity, acting on phosphorus-nitrogen bonds
+property_value: skos:exactMatch EC:3.9.1.1
+property_value: skos:exactMatch RHEA:12977
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050188
@@ -317106,6 +329570,9 @@
xref: MetaCyc:PHOSPHOENOLPYRUVATE-MUTASE-RXN
xref: RHEA:17013
is_a: GO:0016868 ! intramolecular phosphotransferase activity
+property_value: skos:exactMatch EC:5.4.2.9
+property_value: skos:exactMatch RHEA:17013
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050189
@@ -317119,6 +329586,9 @@
xref: MetaCyc:PHOSPHOENOLPYRUVATE-PHOSPHATASE-RXN
xref: RHEA:19997
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.60
+property_value: skos:exactMatch RHEA:19997
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050190
@@ -317135,6 +329605,9 @@
xref: RHEA:13377
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.10
+property_value: skos:exactMatch RHEA:13377
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050191
@@ -317148,6 +329621,9 @@
xref: RHEA:23332
is_a: GO:0016301 ! kinase activity
is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor
+property_value: skos:exactMatch EC:2.7.2.10
+property_value: skos:exactMatch RHEA:23332
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050192
@@ -317162,6 +329638,9 @@
xref: MetaCyc:PHOSPHOGLYCERATE-PHOSPHATASE-RXN
xref: RHEA:21156
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.20
+property_value: skos:exactMatch RHEA:21156
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050193
@@ -317175,6 +329654,9 @@
xref: MetaCyc:PHOSPHOKETOLASE-RXN
xref: RHEA:10468
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.9
+property_value: skos:exactMatch RHEA:10468
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050194
@@ -317189,7 +329671,10 @@
xref: KEGG_REACTION:R00747
xref: MetaCyc:PHOSPHONOACETALDEHYDE-HYDROLASE-RXN
xref: RHEA:18905
-is_a: GO:0016827 ! hydrolase activity, acting on acid carbon-phosphorus bonds
+is_a: GO:0016827 ! hydrolase activity, acting on carbon-phosphorus bonds
+property_value: skos:exactMatch EC:3.11.1.1
+property_value: skos:exactMatch RHEA:18905
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050195
@@ -317204,6 +329689,9 @@
xref: RHEA:21216
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.18
+property_value: skos:exactMatch RHEA:21216
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050196
@@ -317220,6 +329708,8 @@
xref: EC:3.1.3.17
xref: MetaCyc:PHOSPHORYLASE-PHOSPHATASE-RXN
is_a: GO:0004721 ! phosphoprotein phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.17
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050197
@@ -317235,6 +329725,9 @@
xref: RHEA:21380
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.24
+property_value: skos:exactMatch RHEA:21380
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050198
@@ -317249,6 +329742,9 @@
xref: MetaCyc:PINOSYLVIN-SYNTHASE-RXN
xref: RHEA:12552
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.146
+property_value: skos:exactMatch RHEA:12552
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050199
@@ -317263,6 +329759,9 @@
xref: MetaCyc:PIPERIDINE-N-PIPEROYLTRANSFERASE-RXN
xref: RHEA:14561
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.145
+property_value: skos:exactMatch RHEA:14561
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050200
@@ -317296,6 +329795,9 @@
xref: RHEA:13241
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.52
+property_value: skos:exactMatch RHEA:13241
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050202
@@ -317310,6 +329812,9 @@
xref: MetaCyc:OCTOPAMINE-DEHYDRATASE-RXN
xref: RHEA:18173
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.87
+property_value: skos:exactMatch RHEA:18173
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050203
@@ -317325,6 +329830,9 @@
xref: RHEA:18293
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch EC:6.2.1.8
+property_value: skos:exactMatch RHEA:18293
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050204
@@ -317338,6 +329846,9 @@
xref: MetaCyc:OXALOMALATE-LYASE-RXN
xref: RHEA:22032
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.13
+property_value: skos:exactMatch RHEA:22032
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050205
@@ -317351,6 +329862,9 @@
xref: MetaCyc:OXAMATE-CARBAMOYLTRANSFERASE-RXN
xref: RHEA:22984
is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity
+property_value: skos:exactMatch EC:2.1.3.5
+property_value: skos:exactMatch RHEA:22984
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050206
@@ -317368,6 +329882,9 @@
xref: MetaCyc:OXIMINOTRANSFERASE-RXN
xref: RHEA:11624
is_a: GO:0016769 ! transferase activity, transferring nitrogenous groups
+property_value: skos:exactMatch EC:2.6.3.1
+property_value: skos:exactMatch RHEA:11624
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050207
@@ -317382,7 +329899,10 @@
xref: MetaCyc:RXN-17732
xref: RHEA:22956
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.77
+property_value: skos:exactMatch RHEA:22956
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24969" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050208
@@ -317394,6 +329914,9 @@
xref: MetaCyc:POLYSIALIC-ACID-O-ACETYLTRANSFERASE-RXN
xref: RHEA:11604
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.136
+property_value: skos:exactMatch RHEA:11604
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050209
@@ -317407,6 +329930,9 @@
xref: MetaCyc:POLYVINYL-ALCOHOL-OXIDASE-RXN
xref: RHEA:21688
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.30
+property_value: skos:exactMatch RHEA:21688
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050210
@@ -317421,6 +329947,9 @@
xref: MetaCyc:PRENYL-PYROPHOSPHATASE-RXN
xref: RHEA:21496
is_a: GO:0016794 ! diphosphoric monoester hydrolase activity
+property_value: skos:exactMatch EC:3.1.7.1
+property_value: skos:exactMatch RHEA:21496
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050211
@@ -317442,6 +329971,9 @@
xref: RHEA:12637
is_a: GO:0035250 ! UDP-galactosyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.4.1.50
+property_value: skos:exactMatch RHEA:12637
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050212
@@ -317459,7 +329991,10 @@
xref: PMID:39766209
xref: RHEA:18205
is_a: GO:0050214 ! progesterone monooxygenase activity
+property_value: skos:exactMatch EC:1.14.99.14
+property_value: skos:exactMatch RHEA:18205
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29311" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050213
@@ -317489,6 +330024,9 @@
xref: RHEA:11984
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.4
+property_value: skos:exactMatch RHEA:11984
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050215
@@ -317511,6 +330049,9 @@
xref: MetaCyc:PROPANEDIOL-DEHYDRATASE-RXN
xref: RHEA:14569
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.28
+property_value: skos:exactMatch RHEA:14569
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050216
@@ -317522,6 +330063,9 @@
xref: MetaCyc:PROPANEDIOL-PHOSPHATE-DEHYDROGENASE-RXN
xref: RHEA:21584
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.7
+property_value: skos:exactMatch RHEA:21584
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050217
@@ -317536,6 +330080,9 @@
xref: MetaCyc:PROPIOIN-SYNTHASE-RXN
xref: RHEA:11100
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.35
+property_value: skos:exactMatch RHEA:11100
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050218
@@ -317548,7 +330095,10 @@
xref: MetaCyc:PROPIONATE--COA-LIGASE-RXN
xref: RHEA:20373
is_a: GO:0031955 ! short-chain fatty acid-CoA ligase activity
+property_value: skos:exactMatch EC:6.2.1.17
+property_value: skos:exactMatch RHEA:20373
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26440" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050219
@@ -317563,6 +330113,9 @@
xref: MetaCyc:PROSTAGLANDIN-A1-DELTA-ISOMERASE-RXN
xref: RHEA:10460
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.9
+property_value: skos:exactMatch RHEA:10460
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050220
@@ -317587,6 +330140,9 @@
xref: Reactome:R-HSA-265295 "Prostaglandin E synthase isomerizes PGH2 to PGE2"
xref: RHEA:12893
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:exactMatch EC:5.3.99.3
+property_value: skos:exactMatch RHEA:12893
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050221
@@ -317614,6 +330170,9 @@
xref: Reactome:R-HSA-2161651 "PGE2 is converted to PGF2a by CBR1"
xref: RHEA:24508
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.189
+property_value: skos:exactMatch RHEA:24508
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050223
@@ -317629,6 +330188,9 @@
xref: MetaCyc:PROTOCATECHUATE-DECARBOXYLASE-RXN
xref: RHEA:22416
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.63
+property_value: skos:exactMatch RHEA:22416
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050224
@@ -317643,6 +330205,9 @@
xref: MetaCyc:PRUNASIN-BETA-GLUCOSIDASE-RXN
xref: RHEA:16489
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.118
+property_value: skos:exactMatch RHEA:16489
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050225
@@ -317657,6 +330222,9 @@
xref: RHEA:22448
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.83
+property_value: skos:exactMatch RHEA:22448
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050226
@@ -317671,6 +330239,9 @@
xref: MetaCyc:PSYCHOSINE-SULFOTRANSFERASE-RXN
xref: RHEA:14137
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.13
+property_value: skos:exactMatch RHEA:14137
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050227
@@ -317682,6 +330253,9 @@
xref: MetaCyc:PTERIDINE-OXIDASE-RXN
xref: RHEA:12777
is_a: GO:0016727 ! oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor
+property_value: skos:exactMatch EC:1.17.3.1
+property_value: skos:exactMatch RHEA:12777
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050228
@@ -317695,7 +330269,10 @@
xref: RHEA:36055
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.11
+property_value: skos:exactMatch RHEA:36055
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30157" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050229
@@ -317722,6 +330299,8 @@
xref: MetaCyc:PURINE-IMIDAZOLE-RING-CYCLASE-RXN
is_a: GO:0009975 ! cyclase activity
is_a: GO:0016842 ! amidine-lyase activity
+property_value: skos:exactMatch EC:4.3.2.4
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050231
@@ -317737,6 +330316,9 @@
xref: MetaCyc:PUTRESCINE-CARBAMOYLTRANSFERASE-RXN
xref: RHEA:21936
is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity
+property_value: skos:exactMatch EC:2.1.3.6
+property_value: skos:exactMatch RHEA:21936
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050232
@@ -317748,6 +330330,8 @@
xref: MetaCyc:PUTRESCINE-OXIDASE-RXN
xref: RHEA:18273
is_a: GO:0052597 ! diamine oxidase activity
+property_value: skos:exactMatch EC:1.4.3.10
+property_value: skos:exactMatch RHEA:18273
[Term]
id: GO:0050233
@@ -317762,6 +330346,9 @@
xref: MetaCyc:PYRANOSE-OXIDASE-RXN
xref: RHEA:10552
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.10
+property_value: skos:exactMatch RHEA:10552
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050234
@@ -317776,6 +330363,9 @@
xref: MetaCyc:PYRAZOLYLALANINE-SYNTHASE-RXN
xref: RHEA:24512
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.50
+property_value: skos:exactMatch RHEA:24512
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050235
@@ -317789,6 +330379,9 @@
xref: MetaCyc:PYRIDOXAL-4-DEHYDROGENASE-RXN
xref: RHEA:21336
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.107
+property_value: skos:exactMatch RHEA:21336
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050236
@@ -317807,6 +330400,8 @@
xref: MetaCyc:PYRIDOXINE-4-DEHYDROGENASE-RXN
xref: RHEA:16129
is_a: GO:0008106 ! alcohol dehydrogenase (NADP+) activity
+property_value: skos:exactMatch EC:1.1.1.65
+property_value: skos:exactMatch RHEA:16129
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28532" xsd:anyURI
[Term]
@@ -317821,6 +330416,9 @@
xref: MetaCyc:PYRIDOXINE-4-OXIDASE-RXN
xref: RHEA:15033
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.12
+property_value: skos:exactMatch RHEA:15033
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050238
@@ -317837,6 +330435,9 @@
xref: MetaCyc:PYRIDOXINE-5-DEHYDROGENASE-RXN
xref: RHEA:14497
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.9
+property_value: skos:exactMatch RHEA:14497
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050239
@@ -317849,6 +330450,9 @@
xref: RHEA:14537
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.20
+property_value: skos:exactMatch RHEA:14537
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050240
@@ -317862,6 +330466,9 @@
xref: MetaCyc:PYROGALLOL-12-OXYGENASE-RXN
xref: RHEA:19673
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.35
+property_value: skos:exactMatch RHEA:19673
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050241
@@ -317873,6 +330480,8 @@
xref: EC:1.5.1.1
xref: MetaCyc:PYRROLINE-2-CARBOXYLATE-REDUCTASE-RXN
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.1
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050242
@@ -317896,6 +330505,9 @@
xref: MetaCyc:PYRUVATEORTHOPHOSPHATE-DIKINASE-RXN
xref: RHEA:10756
is_a: GO:0016781 ! phosphotransferase activity, paired acceptors
+property_value: skos:exactMatch EC:2.7.9.1
+property_value: skos:exactMatch RHEA:10756
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050243
@@ -317910,6 +330522,8 @@
xref: MetaCyc:PYRUVATE-DEHYDROGENASE-NADP+-RXN
xref: RHEA:17425
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.51
+property_value: skos:exactMatch RHEA:17425
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24350" xsd:anyURI
[Term]
@@ -317923,6 +330537,9 @@
xref: MetaCyc:PYRUVATE-OXIDASE-COA-ACETYLATING-RXN
xref: RHEA:21912
is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.2.3.6
+property_value: skos:exactMatch RHEA:21912
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050245
@@ -317946,6 +330563,9 @@
xref: MetaCyc:QUESTIN-MONOOXYGENASE-RXN
xref: RHEA:10836
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.43
+property_value: skos:exactMatch RHEA:10836
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050247
@@ -317961,6 +330581,9 @@
xref: MetaCyc:RAUCAFFRICINE-BETA-GLUCOSIDASE-RXN
xref: RHEA:14557
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.125
+property_value: skos:exactMatch RHEA:14557
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050248
@@ -317977,6 +330600,9 @@
xref: RHEA:14765
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
is_a: GO:0045289 ! luciferin monooxygenase activity
+property_value: skos:exactMatch EC:1.13.12.5
+property_value: skos:exactMatch RHEA:14765
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050249
@@ -317993,6 +330619,9 @@
xref: MetaCyc:RENILLA-LUCIFERIN-SULFOTRANSFERASE-RXN
xref: RHEA:20481
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.10
+property_value: skos:exactMatch RHEA:20481
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050251
@@ -318005,6 +330634,8 @@
xref: Reactome:R-HSA-2465926 "An atROL isomerase isomerises atROL to 11cROL"
xref: RHEA:19141
is_a: GO:0016859 ! cis-trans isomerase activity
+property_value: skos:exactMatch RHEA:19141
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050252
@@ -318021,6 +330652,9 @@
xref: RHEA:11488
is_a: GO:0008374 ! O-acyltransferase activity
relationship: part_of GO:0042572 ! retinol metabolic process
+property_value: skos:exactMatch EC:2.3.1.76
+property_value: skos:exactMatch RHEA:11488
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050253
@@ -318039,8 +330673,10 @@
xref: RHEA:21508
is_a: GO:0052689 ! carboxylic ester hydrolase activity
relationship: part_of GO:0042572 ! retinol metabolic process
+property_value: skos:exactMatch RHEA:21508
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24923" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050254
@@ -318057,7 +330693,11 @@
xref: Reactome:R-HSA-2581474 "GRK1,4,7 phosphorylate MII to p-MII"
xref: RHEA:23356
is_a: GO:0004703 ! G protein-coupled receptor kinase activity
+property_value: skos:exactMatch EC:2.7.11.14
+property_value: skos:exactMatch RHEA:23356
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23314" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0050255
@@ -318074,6 +330714,9 @@
xref: MetaCyc:RIBITOL-2-DEHYDROGENASE-RXN
xref: RHEA:20053
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.56
+property_value: skos:exactMatch RHEA:20053
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050256
@@ -318084,7 +330727,12 @@
synonym: "dehydrogenase, ribitol 5-phosphate" RELATED [EC:1.1.1.137]
xref: EC:1.1.1.137
xref: MetaCyc:RIBITOL-5-PHOSPHATE-2-DEHYDROGENASE-RXN
+xref: RHEA:19921
+xref: RHEA:19925
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.137
+property_value: skos:narrowMatch RHEA:19921
+property_value: skos:narrowMatch RHEA:19925
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
[Term]
@@ -318102,6 +330750,9 @@
xref: RHEA:20409
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.42
+property_value: skos:exactMatch RHEA:20409
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050258
@@ -318114,6 +330765,9 @@
xref: MetaCyc:RIBOFLAVINASE-RXN
xref: RHEA:11408
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch EC:3.5.99.1
+property_value: skos:exactMatch RHEA:11408
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050259
@@ -318128,6 +330782,9 @@
xref: MetaCyc:RIBOSE-1-DEHYDROGENASE-NADP+-RXN
xref: RHEA:11676
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.115
+property_value: skos:exactMatch RHEA:11676
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050260
@@ -318143,6 +330800,9 @@
xref: MetaCyc:RIBOSE-5-PHOSPHATE--AMMONIA-LIGASE-RXN
xref: RHEA:13777
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
+property_value: skos:exactMatch EC:6.3.4.7
+property_value: skos:exactMatch RHEA:13777
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050261
@@ -318157,6 +330817,9 @@
xref: MetaCyc:RIBOSE-ISOMERASE-RXN
xref: RHEA:20796
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.20
+property_value: skos:exactMatch RHEA:20796
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050262
@@ -318175,7 +330838,11 @@
xref: RHEA:14017
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.22
+property_value: skos:exactMatch MetaCyc:RIBOSYLNICOTINAMIDE-KINASE-RXN
+property_value: skos:exactMatch RHEA:14017
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29467" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0050263
@@ -318193,6 +330860,9 @@
xref: MetaCyc:RIBOSYLPYRIMIDINE-NUCLEOSIDASE-RXN
xref: RHEA:56816
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.2.8
+property_value: skos:exactMatch RHEA:56816
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050264
@@ -318207,6 +330877,9 @@
xref: MetaCyc:RIFAMYCIN-B-OXIDASE-RXN
xref: RHEA:11292
is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.10.3.6
+property_value: skos:exactMatch RHEA:11292
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050265
@@ -318224,6 +330897,9 @@
xref: RHEA:14785
is_a: GO:0070569 ! uridylyltransferase activity
is_a: GO:0140098 ! catalytic activity, acting on RNA
+property_value: skos:exactMatch EC:2.7.7.52
+property_value: skos:exactMatch RHEA:14785
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050266
@@ -318238,6 +330914,9 @@
xref: MetaCyc:RXN-7633
xref: RHEA:22344
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.140
+property_value: skos:exactMatch RHEA:22344
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050267
@@ -318255,6 +330934,8 @@
xref: MetaCyc:2.5.1.20-RXN
xref: RHEA:18801
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.20
+property_value: skos:exactMatch RHEA:18801
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
[Term]
@@ -318267,7 +330948,10 @@
xref: MetaCyc:RXN-2602
xref: RHEA:22444
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.194
+property_value: skos:exactMatch RHEA:22444
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050269
@@ -318277,7 +330961,13 @@
synonym: "coniferyl aldehyde:NAD(P)+ oxidoreductase activity" RELATED [EC:1.2.1.68]
xref: EC:1.2.1.68
xref: MetaCyc:RXN-1241
+xref: RHEA:23964
+xref: RHEA:23968
is_a: GO:0004030 ! aldehyde dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.2.1.68
+property_value: skos:narrowMatch RHEA:23964
+property_value: skos:narrowMatch RHEA:23968
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050270
@@ -318292,6 +330982,9 @@
xref: RHEA:20716
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.28
+property_value: skos:exactMatch RHEA:20716
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050271
@@ -318316,6 +331009,9 @@
xref: MetaCyc:S-CARBOXYMETHYLCYSTEINE-SYNTHASE-RXN
xref: RHEA:22868
is_a: GO:0016848 ! carbon-halide lyase activity
+property_value: skos:exactMatch EC:4.5.1.5
+property_value: skos:exactMatch RHEA:22868
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050273
@@ -318327,6 +331023,9 @@
xref: MetaCyc:S-SUCCINYLGLUTATHIONE-HYDROLASE-RXN
xref: RHEA:16713
is_a: GO:0016790 ! thiolester hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.13
+property_value: skos:exactMatch RHEA:16713
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050274
@@ -318344,6 +331043,9 @@
xref: MetaCyc:SALICYL-ALCOHOL-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:11512
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.172
+property_value: skos:exactMatch RHEA:11512
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050275
@@ -318360,6 +331062,9 @@
xref: MetaCyc:SCOPOLETIN-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:20453
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.128
+property_value: skos:exactMatch RHEA:20453
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050276
@@ -318376,6 +331081,9 @@
xref: RHEA:18605
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.65
+property_value: skos:exactMatch RHEA:18605
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050277
@@ -318392,6 +331100,9 @@
xref: RHEA:23844
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.14
+property_value: skos:exactMatch RHEA:23844
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050278
@@ -318410,6 +331121,9 @@
xref: MetaCyc:SEDOHEPTULOSE-BISPHOSPHATASE-RXN
xref: RHEA:17461
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.37
+property_value: skos:exactMatch RHEA:17461
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050279
@@ -318422,6 +331136,9 @@
xref: RHEA:14025
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.24
+property_value: skos:exactMatch RHEA:14025
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050280
@@ -318434,6 +331151,9 @@
xref: MetaCyc:SEQUOYITOL-DEHYDROGENASE-RXN
xref: RHEA:11300
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.143
+property_value: skos:exactMatch RHEA:11300
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050281
@@ -318447,6 +331167,9 @@
xref: MetaCyc:SERINE--GLYOXYLATE-AMINOTRANSFERASE-RXN
xref: RHEA:19125
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.45
+property_value: skos:exactMatch RHEA:19125
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050282
@@ -318460,6 +331183,9 @@
xref: MetaCyc:SERINE-DEHYDROGENASE-RXN
xref: RHEA:20884
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.7
+property_value: skos:exactMatch RHEA:20884
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050283
@@ -318473,6 +331199,9 @@
xref: MetaCyc:SERINE-SULFATE-AMMONIA-LYASE-RXN
xref: RHEA:15605
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:exactMatch EC:4.3.1.10
+property_value: skos:exactMatch RHEA:15605
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050284
@@ -318488,6 +331217,9 @@
xref: MetaCyc:SINAPATE-1-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:13305
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.120
+property_value: skos:exactMatch RHEA:13305
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050285
@@ -318501,6 +331233,9 @@
xref: MetaCyc:SINAPINE-ESTERASE-RXN
xref: RHEA:10016
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.49
+property_value: skos:exactMatch RHEA:10016
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050286
@@ -318514,6 +331249,9 @@
xref: MetaCyc:SORBITOL-6-PHOSPHATASE-RXN
xref: RHEA:24580
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.50
+property_value: skos:exactMatch RHEA:24580
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050287
@@ -318530,6 +331268,9 @@
xref: MetaCyc:SORBOSE-5-DEHYDROGENASE-NADP+-RXN
xref: RHEA:15001
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.123
+property_value: skos:exactMatch RHEA:15001
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050288
@@ -318543,6 +331284,9 @@
xref: MetaCyc:SORBOSE-DEHYDROGENASE-RXN
xref: RHEA:14713
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.12
+property_value: skos:exactMatch RHEA:14713
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050289
@@ -318555,6 +331299,9 @@
xref: MetaCyc:SPERMIDINE-DEHYDROGENASE-RXN
xref: RHEA:14273
is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors
+property_value: skos:exactMatch EC:1.5.99.6
+property_value: skos:exactMatch RHEA:14273
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050290
@@ -318567,8 +331314,10 @@
xref: KEGG_REACTION:R02542
xref: MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-D-RXN
xref: RHEA:20984
-is_a: GO:0004620 ! phospholipase activity
-is_a: GO:0008081 ! phosphoric diester hydrolase activity
+is_a: GO:0004767 ! sphingomyelin phosphodiesterase activity
+property_value: skos:exactMatch EC:3.1.4.41
+property_value: skos:exactMatch RHEA:20984
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050291
@@ -318585,6 +331334,9 @@
xref: Reactome:R-HSA-428185 "Ceramide synthases transfer acyl-CoA onto sphingoid"
xref: RHEA:23768
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.24
+property_value: skos:exactMatch RHEA:23768
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050292
@@ -318602,6 +331354,9 @@
xref: RHEA:19557
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.24
+property_value: skos:exactMatch RHEA:19557
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050293
@@ -318614,6 +331369,9 @@
xref: MetaCyc:STEROID-LACTONASE-RXN
xref: RHEA:13721
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.37
+property_value: skos:exactMatch RHEA:13721
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050294
@@ -318631,7 +331389,10 @@
xref: Reactome:R-HSA-176631 "dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP"
xref: RHEA:68460
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.15
+property_value: skos:exactMatch RHEA:68460
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050295
@@ -318645,6 +331406,9 @@
xref: MetaCyc:STERYL-BETA-GLUCOSIDASE-RXN
xref: RHEA:11956
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.104
+property_value: skos:exactMatch RHEA:11956
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050296
@@ -318658,6 +331422,9 @@
xref: MetaCyc:STIPITATONATE-DECARBOXYLASE-RXN
xref: RHEA:13885
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.60
+property_value: skos:exactMatch RHEA:13885
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050297
@@ -318670,7 +331437,10 @@
xref: MetaCyc:RXN-8460
xref: RHEA:21220
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.29
+property_value: skos:exactMatch RHEA:21220
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28192" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050298
@@ -318682,6 +331452,9 @@
xref: MetaCyc:STIZOLOBINATE-SYNTHASE-RXN
xref: RHEA:18465
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.30
+property_value: skos:exactMatch RHEA:18465
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050299
@@ -318696,6 +331469,9 @@
xref: MetaCyc:STREPTOMYCIN-3-KINASE-RXN
xref: RHEA:18377
is_a: GO:0034071 ! aminoglycoside phosphotransferase activity
+property_value: skos:exactMatch EC:2.7.1.87
+property_value: skos:exactMatch RHEA:18377
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050300
@@ -318716,6 +331492,9 @@
xref: MetaCyc:STREPTOMYCIN-6-KINASE-RXN
xref: RHEA:22268
is_a: GO:0034071 ! aminoglycoside phosphotransferase activity
+property_value: skos:exactMatch EC:2.7.1.72
+property_value: skos:exactMatch RHEA:22268
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050301
@@ -318731,6 +331510,9 @@
xref: MetaCyc:STREPTOMYCIN-6-PHOSPHATASE-RXN
xref: RHEA:10688
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.39
+property_value: skos:exactMatch RHEA:10688
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050302
@@ -318748,6 +331530,9 @@
xref: MetaCyc:INDOLE-3-ACETALDEHYDE-OXIDASE-RXN
xref: RHEA:16277
is_a: GO:0018488 ! aryl-aldehyde oxidase activity
+property_value: skos:exactMatch EC:1.2.3.7
+property_value: skos:exactMatch RHEA:16277
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050303
@@ -318763,6 +331548,10 @@
xref: MetaCyc:LYSINE-6-DEHYDROGENASE-RXN
xref: RHEA:12408
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.18
+property_value: skos:exactMatch MetaCyc:LYSINE-6-DEHYDROGENASE-RXN
+property_value: skos:exactMatch RHEA:12408
+property_value: skos:relatedMatch MetaCyc:PWY-5314
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -318779,6 +331568,9 @@
xref: MetaCyc:RXN-12130
xref: RHEA:43108
is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.7.2.4
+property_value: skos:exactMatch RHEA:43108
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050305
@@ -318793,6 +331585,9 @@
xref: MetaCyc:STROMBINE-DEHYDROGENASE-RXN
xref: RHEA:14061
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.22
+property_value: skos:exactMatch RHEA:14061
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050306
@@ -318811,6 +331606,9 @@
xref: MetaCyc:RXN-1781
xref: RHEA:23312
is_a: GO:0050738 ! fructosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.99
+property_value: skos:exactMatch RHEA:23312
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050307
@@ -318825,6 +331623,9 @@
xref: MetaCyc:SUCROSE-PHOSPHATASE-RXN
xref: RHEA:19289
is_a: GO:0050308 ! sugar-phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.24
+property_value: skos:exactMatch RHEA:19289
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050308
@@ -318837,6 +331638,8 @@
xref: KEGG_REACTION:R00804
xref: MetaCyc:SUGAR-PHOSPHATASE-RXN
is_a: GO:0019203 ! carbohydrate phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.23
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050309
@@ -318847,6 +331650,8 @@
synonym: "xylitol-5-phosphatase activity" NARROW [EC:3.1.3.58]
xref: EC:3.1.3.58
is_a: GO:0050308 ! sugar-phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.58
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050310
@@ -318861,6 +331666,9 @@
xref: MetaCyc:SULFITE-DEHYDROGENASE-RXN
xref: RHEA:14281
is_a: GO:0016669 ! oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.8.2.1
+property_value: skos:exactMatch RHEA:14281
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050311
@@ -318874,6 +331682,9 @@
xref: MetaCyc:SULFITE-REDUCTASE-FERREDOXIN-RXN
xref: RHEA:23132
is_a: GO:0016673 ! oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.8.7.1
+property_value: skos:exactMatch RHEA:23132
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050312
@@ -318900,7 +331711,10 @@
xref: Reactome:R-HSA-1614605 "Persulfide sulfur is dioxygenated"
xref: RHEA:12981
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.18
+property_value: skos:exactMatch RHEA:12981
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25809" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050314
@@ -318913,6 +331727,9 @@
xref: MetaCyc:SYM-NORSPERMIDINE-SYNTHASE-RXN
xref: RHEA:23244
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.23
+property_value: skos:exactMatch RHEA:23244
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050315
@@ -318925,6 +331742,9 @@
xref: MetaCyc:SYNEPHRINE-DEHYDRATASE-RXN
xref: RHEA:32203
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.88
+property_value: skos:exactMatch RHEA:32203
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050316
@@ -318936,6 +331756,9 @@
xref: MetaCyc:GMKALT-RXN
xref: RHEA:12697
is_a: GO:0047507 ! deoxynucleoside phosphate kinase activity, ATP as phosphate donor
+property_value: skos:broadMatch EC:2.7.4.12
+property_value: skos:exactMatch MetaCyc:GMKALT-RXN
+property_value: skos:exactMatch RHEA:12697
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29533" xsd:anyURI
[Term]
@@ -318952,6 +331775,9 @@
xref: RHEA:15513
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.101
+property_value: skos:exactMatch RHEA:15513
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050318
@@ -318966,6 +331792,9 @@
xref: MetaCyc:TANNASE-RXN
xref: RHEA:16365
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.20
+property_value: skos:exactMatch RHEA:16365
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050319
@@ -318979,6 +331808,9 @@
xref: MetaCyc:TARTRATE-DECARBOXYLASE-RXN
xref: RHEA:13317
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.73
+property_value: skos:exactMatch RHEA:13317
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050320
@@ -318991,6 +331823,9 @@
xref: MetaCyc:TARTRATE-EPIMERASE-RXN
xref: RHEA:22212
is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives
+property_value: skos:exactMatch EC:5.1.2.5
+property_value: skos:exactMatch RHEA:22212
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050321
@@ -319017,7 +331852,13 @@
synonym: "TTK" RELATED [EC:2.7.11.26]
xref: EC:2.7.11.26
xref: MetaCyc:TAU-PROTEIN-KINASE-RXN
+xref: RHEA:12801
+xref: RHEA:53904
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:exactMatch EC:2.7.11.26
+property_value: skos:exactMatch MetaCyc:TAU-PROTEIN-KINASE-RXN
+property_value: skos:narrowMatch RHEA:12801
+property_value: skos:narrowMatch RHEA:53904
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29107" xsd:anyURI
[Term]
@@ -319034,6 +331875,9 @@
xref: MetaCyc:RXN-2301
xref: RHEA:16353
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.55
+property_value: skos:exactMatch RHEA:16353
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050323
@@ -319047,6 +331891,9 @@
xref: MetaCyc:TAURINE-DEHYDROGENASE-RXN
xref: RHEA:18709
is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors
+property_value: skos:exactMatch EC:1.4.99.2
+property_value: skos:exactMatch RHEA:18709
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050324
@@ -319062,6 +331909,9 @@
xref: RHEA:22516
is_a: GO:0016301 ! kinase activity
is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor
+property_value: skos:exactMatch EC:2.7.3.4
+property_value: skos:exactMatch RHEA:22516
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050325
@@ -319075,6 +331925,9 @@
xref: MetaCyc:TAUROPINE-DEHYDROGENASE-RXN
xref: RHEA:12580
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.23
+property_value: skos:exactMatch RHEA:12580
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050326
@@ -319086,6 +331939,8 @@
xref: EC:1.14.13.19
xref: MetaCyc:TAXIFOLIN-8-MONOOXYGENASE-RXN
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.19
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050328
@@ -319099,6 +331954,9 @@
xref: MetaCyc:TETRAHYDROBERBERINE-OXIDASE-RXN
xref: RHEA:13489
is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.3.3.8
+property_value: skos:exactMatch RHEA:13489
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050329
@@ -319111,6 +331969,9 @@
xref: MetaCyc:TETRAHYDROXYPTERIDINE-CYCLOISOMERASE-RXN
xref: RHEA:18097
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.3
+property_value: skos:exactMatch RHEA:18097
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050330
@@ -319125,6 +331986,9 @@
xref: MetaCyc:THEANINE-HYDROLASE-RXN
xref: RHEA:18013
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.65
+property_value: skos:exactMatch RHEA:18013
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050331
@@ -319146,6 +332010,9 @@
xref: RHEA:11240
is_a: GO:0016301 ! kinase activity
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
+property_value: skos:exactMatch EC:2.7.4.15
+property_value: skos:exactMatch RHEA:11240
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050332
@@ -319166,6 +332033,9 @@
xref: MetaCyc:THIAMIN-PYRIDINYLASE-RXN
xref: RHEA:17697
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.2
+property_value: skos:exactMatch RHEA:17697
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050333
@@ -319184,6 +332054,9 @@
xref: Reactome:R-HSA-965067 "THTPA:Mg2+ hydrolyzes ThTP to TDP"
xref: RHEA:11744
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.28
+property_value: skos:exactMatch RHEA:11744
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050334
@@ -319196,6 +332069,9 @@
xref: MetaCyc:THIAMINASE-RXN
xref: RHEA:17509
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch EC:3.5.99.2
+property_value: skos:exactMatch RHEA:17509
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050335
@@ -319220,6 +332096,9 @@
xref: MetaCyc:THIOETHANOLAMINE-S-ACETYLTRANSFERASE-RXN
xref: RHEA:23280
is_a: GO:0016418 ! S-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.11
+property_value: skos:exactMatch RHEA:23280
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050337
@@ -319236,6 +332115,9 @@
xref: Reactome:R-HSA-1655879 "Thiosulfate can transfer its sulfur atom to glutathione"
xref: RHEA:14505
is_a: GO:0016783 ! sulfurtransferase activity
+property_value: skos:exactMatch EC:2.8.1.3
+property_value: skos:exactMatch RHEA:14505
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050338
@@ -319252,6 +332134,9 @@
xref: MetaCyc:THIOSULFATE-DEHYDROGENASE-RXN
xref: RHEA:20549
is_a: GO:0016669 ! oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.8.2.2
+property_value: skos:exactMatch RHEA:20549
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050339
@@ -319268,6 +332153,9 @@
xref: MetaCyc:THYMIDINE-TRIPHOSPHATASE-RXN
xref: RHEA:19013
is_a: GO:0017111 ! ribonucleoside triphosphate phosphatase activity
+property_value: skos:exactMatch EC:3.6.1.39
+property_value: skos:exactMatch RHEA:19013
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050340
@@ -319302,6 +332190,9 @@
xref: MetaCyc:THYMINE-DIOXYGENASE-RXN
xref: RHEA:10316
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.6
+property_value: skos:exactMatch RHEA:10316
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050342
@@ -319313,7 +332204,17 @@
synonym: "tocopherol O-methyltransferase activity" EXACT []
xref: EC:2.1.1.95
xref: MetaCyc:TOCOPHEROL-O-METHYLTRANSFERASE-RXN
+xref: RHEA:24012
+xref: RHEA:37991
+xref: RHEA:38091
+xref: RHEA:38095
is_a: GO:0008171 ! O-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.95
+property_value: skos:narrowMatch RHEA:24012
+property_value: skos:narrowMatch RHEA:37991
+property_value: skos:narrowMatch RHEA:38091
+property_value: skos:narrowMatch RHEA:38095
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050343
@@ -319325,7 +332226,10 @@
xref: MetaCyc:TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN
xref: RHEA:18177
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.44
+property_value: skos:exactMatch RHEA:18177
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050344
@@ -319343,6 +332247,9 @@
xref: MetaCyc:TRANS-CINNAMATE-2-MONOOXYGENASE-RXN
xref: RHEA:10956
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.14
+property_value: skos:exactMatch RHEA:10956
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050345
@@ -319357,6 +332264,9 @@
xref: MetaCyc:TRANS-EPOXYSUCCINATE-HYDROLASE-RXN
xref: RHEA:20740
is_a: GO:0016803 ! ether hydrolase activity
+property_value: skos:exactMatch EC:3.3.2.4
+property_value: skos:exactMatch RHEA:20740
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050346
@@ -319370,6 +332280,9 @@
xref: MetaCyc:TRANS-L-3-HYDROXYPROLINE-DEHYDRATASE-RXN
xref: RHEA:10320
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.77
+property_value: skos:exactMatch RHEA:10320
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050348
@@ -319383,6 +332296,9 @@
xref: MetaCyc:RXN1G-874
xref: RHEA:23472
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.122
+property_value: skos:exactMatch RHEA:23472
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050349
@@ -319399,6 +332315,9 @@
xref: MetaCyc:RXN-20777
xref: RHEA:22260
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.38
+property_value: skos:exactMatch RHEA:22260
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050350
@@ -319412,6 +332331,9 @@
xref: MetaCyc:RXN-87
xref: RHEA:11936
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.95
+property_value: skos:exactMatch RHEA:11936
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050351
@@ -319425,6 +332347,9 @@
xref: MetaCyc:TRIMETAPHOSPHATASE-RXN
xref: RHEA:11088
is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
+property_value: skos:exactMatch EC:3.6.1.2
+property_value: skos:exactMatch RHEA:11088
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050352
@@ -319442,6 +332367,9 @@
xref: RHEA:20217
xref: UM-BBD_reactionID:r1409
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.32
+property_value: skos:exactMatch RHEA:20217
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050353
@@ -319463,6 +332391,9 @@
xref: Reactome:R-HSA-71241 "TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA"
xref: RHEA:14181
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.8
+property_value: skos:exactMatch RHEA:14181
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050354
@@ -319480,6 +332411,9 @@
xref: RHEA:13941
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.28
+property_value: skos:exactMatch RHEA:13941
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050355
@@ -319495,7 +332429,10 @@
xref: MetaCyc:TRIPHOSPHATASE-RXN
xref: RHEA:14157
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.25
+property_value: skos:exactMatch RHEA:14157
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050356
@@ -319508,6 +332445,9 @@
xref: MetaCyc:TROPINE-DEHYDROGENASE-RXN
xref: RHEA:18357
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.206
+property_value: skos:exactMatch RHEA:18357
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050357
@@ -319524,6 +332464,9 @@
xref: MetaCyc:TROPINESTERASE-RXN
xref: RHEA:23304
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.10
+property_value: skos:exactMatch RHEA:23304
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050358
@@ -319539,6 +332482,9 @@
xref: MetaCyc:TROPINONE-REDUCTASE-RXN
xref: RHEA:24244
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.236
+property_value: skos:exactMatch RHEA:24244
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050359
@@ -319572,6 +332518,9 @@
xref: MetaCyc:TRYPTOPHAN-2-DIOXYGENASE-RXN
xref: RHEA:22620
is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
+property_value: skos:exactMatch EC:1.13.99.3
+property_value: skos:exactMatch RHEA:22620
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050361
@@ -319584,6 +332533,9 @@
xref: MetaCyc:TRYPTOPHAN-2-MONOOXYGENASE-RXN
xref: RHEA:16165
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
+property_value: skos:exactMatch EC:1.13.12.3
+property_value: skos:exactMatch RHEA:16165
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050362
@@ -319601,6 +332553,9 @@
xref: MetaCyc:TRYPTOPHAN-AMINOTRANSFERASE-RXN
xref: RHEA:14093
is_a: GO:0070529 ! L-tryptophan aminotransferase activity
+property_value: skos:exactMatch EC:2.6.1.27
+property_value: skos:exactMatch RHEA:14093
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050363
@@ -319616,6 +332571,8 @@
xref: EC:1.4.1.19
xref: MetaCyc:TRYPTOPHAN-DEHYDROGENASE-RXN
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.19
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050364
@@ -319632,6 +332589,9 @@
xref: MetaCyc:TRYPTOPHAN-DIMETHYLALLYLTRANSFERASE-RXN
xref: RHEA:14173
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.34
+property_value: skos:exactMatch RHEA:14173
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050365
@@ -319646,6 +332606,9 @@
xref: MetaCyc:TRYPTOPHANAMIDASE-RXN
xref: RHEA:11012
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.57
+property_value: skos:exactMatch RHEA:11012
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050366
@@ -319661,6 +332624,9 @@
xref: MetaCyc:TYRAMINE-N-FERULOYLTRANSFERASE-RXN
xref: RHEA:19685
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.110
+property_value: skos:exactMatch RHEA:19685
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050367
@@ -319677,6 +332643,9 @@
xref: MetaCyc:TYROSINE--ARGININE-LIGASE-RXN
xref: RHEA:15345
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.24
+property_value: skos:exactMatch RHEA:15345
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050368
@@ -319690,6 +332659,9 @@
xref: MetaCyc:TYROSINE-23-AMINOMUTASE-RXN
xref: RHEA:15781
is_a: GO:0016869 ! intramolecular aminotransferase activity
+property_value: skos:exactMatch EC:5.4.3.6
+property_value: skos:exactMatch RHEA:15781
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050369
@@ -319705,19 +332677,28 @@
xref: MetaCyc:2.7.11.6-RXN
xref: RHEA:17133
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:exactMatch EC:2.7.11.6
+property_value: skos:exactMatch RHEA:17133
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29107" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0050370
name: tyrosine N-monooxygenase activity
namespace: molecular_function
-def: "Catalysis of the reaction: tyrosine + O2 + NADPH + H+ = N-hydroxytyrosine + NADP+ + H2O." [MetaCyc:TYROSINE-N-MONOOXYGENASE-RXN]
+def: "Catalysis of the reaction: L-tyrosine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = (E)-4-hydroxyphenylacetaldehyde oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H+." [RHEA:32311]
synonym: "CYP79A1 activity" NARROW []
synonym: "L-tyrosine,NADPH:oxygen oxidoreductase (N-hydroxylating)" EXACT []
synonym: "tyrosine N-hydroxylase activity" EXACT []
-xref: MetaCyc:TYROSINE-N-MONOOXYGENASE-RXN
-xref: RHEA:22464
-is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+xref: EC:1.14.14.36
+xref: MetaCyc:RXN-13187
+xref: RHEA:32311
+is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.36
+property_value: skos:exactMatch MetaCyc:RXN-13187
+property_value: skos:exactMatch RHEA:32311
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0050371
@@ -319732,6 +332713,9 @@
xref: MetaCyc:TYROSINE-PHENOL-LYASE-RXN
xref: RHEA:21704
is_a: GO:0016830 ! carbon-carbon lyase activity
+property_value: skos:exactMatch EC:4.1.99.2
+property_value: skos:exactMatch RHEA:21704
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050372
@@ -319764,6 +332748,9 @@
xref: MetaCyc:UDP-ARABINOSE-4-EPIMERASE-RXN
xref: RHEA:11320
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.5
+property_value: skos:exactMatch RHEA:11320
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050374
@@ -319780,6 +332767,9 @@
xref: MetaCyc:UDP-GALACTURONATE-DECARBOXYLASE-RXN
xref: RHEA:19725
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.67
+property_value: skos:exactMatch RHEA:19725
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050376
@@ -319792,6 +332782,9 @@
xref: MetaCyc:UDP-GLUCOSAMINE-EPIMERASE-RXN
xref: RHEA:23492
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.16
+property_value: skos:exactMatch RHEA:23492
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050377
@@ -319809,6 +332802,9 @@
xref: MetaCyc:UDP-GLUCOSE-46-DEHYDRATASE-RXN
xref: RHEA:21500
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.76
+property_value: skos:exactMatch RHEA:21500
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050378
@@ -319828,6 +332824,11 @@
xref: MetaCyc:UDP-GLUCURONATE-4-EPIMERASE-RXN
xref: RHEA:11404
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.6
+property_value: skos:exactMatch KEGG_REACTION:R01385
+property_value: skos:exactMatch MetaCyc:UDP-GLUCURONATE-4-EPIMERASE-RXN
+property_value: skos:exactMatch RHEA:11404
+property_value: skos:relatedMatch MetaCyc:PWY-4861
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -319860,6 +332861,8 @@
xref: MetaCyc:UNDECAPRENYL-DIPHOSPHATASE-RXN
xref: RHEA:28094
is_a: GO:0120556 ! polyprenyl diphosphate phosphatase activity
+property_value: skos:exactMatch EC:3.6.1.27
+property_value: skos:exactMatch RHEA:28094
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21789" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30245" xsd:anyURI
@@ -319876,6 +332879,9 @@
xref: MetaCyc:URACIL-5-CARBOXYLATE-DECARBOXYLASE-RXN
xref: RHEA:17685
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.66
+property_value: skos:exactMatch RHEA:17685
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050383
@@ -319885,6 +332891,8 @@
xref: MetaCyc:URACIL-DEHYDROGENASE-RXN
xref: RHEA:22752
is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups
+property_value: skos:broadMatch EC:1.17.99.4
+property_value: skos:exactMatch RHEA:22752
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -319900,6 +332908,9 @@
xref: MetaCyc:URATE-RIBONUCLEOTIDE-PHOSPHORYLASE-RXN
xref: RHEA:13909
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.16
+property_value: skos:exactMatch RHEA:13909
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050385
@@ -319917,6 +332928,9 @@
xref: MetaCyc:UREIDOGLYCOLATE-LYASE-RXN
xref: RHEA:11304
is_a: GO:0016842 ! amidine-lyase activity
+property_value: skos:exactMatch EC:4.3.2.3
+property_value: skos:exactMatch RHEA:11304
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050386
@@ -319929,6 +332943,9 @@
xref: MetaCyc:UREIDOSUCCINASE-RXN
xref: RHEA:14365
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.7
+property_value: skos:exactMatch RHEA:14365
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050387
@@ -319942,6 +332959,9 @@
xref: MetaCyc:URETHANASE-RXN
xref: RHEA:21372
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.75
+property_value: skos:exactMatch RHEA:21372
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050388
@@ -319956,6 +332976,9 @@
xref: MetaCyc:URONATE-DEHYDROGENASE-RXN
xref: RHEA:22404
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.203
+property_value: skos:exactMatch RHEA:22404
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050389
@@ -319968,6 +332991,9 @@
xref: MetaCyc:URONOLACTONASE-RXN
xref: RHEA:13337
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.19
+property_value: skos:exactMatch RHEA:13337
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050390
@@ -319983,6 +333009,9 @@
xref: RHEA:18989
xref: UM-BBD_reactionID:r1052
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.14
+property_value: skos:exactMatch RHEA:18989
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050391
@@ -319996,7 +333025,10 @@
xref: MetaCyc:VALINE-DEHYDROGENASE-NADP+-RXN
xref: RHEA:11156
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.8
+property_value: skos:exactMatch RHEA:11156
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050392
@@ -320011,6 +333043,9 @@
xref: MetaCyc:VICIANIN-BETA-GLUCOSIDASE-RXN
xref: RHEA:14041
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.119
+property_value: skos:exactMatch RHEA:14041
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050393
@@ -320027,6 +333062,9 @@
xref: MetaCyc:VINYLACETYL-COA-DELTA-ISOMERASE-RXN
xref: RHEA:10572
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.3
+property_value: skos:exactMatch RHEA:10572
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050394
@@ -320041,6 +333079,9 @@
xref: RHEA:20509
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.103
+property_value: skos:exactMatch RHEA:20509
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050395
@@ -320056,6 +333097,9 @@
xref: MetaCyc:VITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:21956
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.105
+property_value: skos:exactMatch RHEA:21956
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050396
@@ -320068,6 +333112,9 @@
xref: MetaCyc:VOMIFOLIOL-4-DEHYDROGENASE-RXN
xref: RHEA:22804
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.221
+property_value: skos:exactMatch RHEA:22804
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050397
@@ -320082,6 +333129,9 @@
xref: RHEA:18057
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
is_a: GO:0045289 ! luciferin monooxygenase activity
+property_value: skos:exactMatch EC:1.13.12.8
+property_value: skos:exactMatch RHEA:18057
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050398
@@ -320095,6 +333145,9 @@
xref: MetaCyc:WAX-ESTER-HYDROLASE-RXN
xref: RHEA:13577
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.50
+property_value: skos:exactMatch RHEA:13577
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050399
@@ -320107,6 +333160,9 @@
xref: MetaCyc:XANTHOMMATIN-REDUCTASE-RXN
xref: RHEA:13417
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.41
+property_value: skos:exactMatch RHEA:13417
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050400
@@ -320121,6 +333177,9 @@
xref: RHEA:20209
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.122
+property_value: skos:exactMatch RHEA:20209
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050401
@@ -320136,6 +333195,9 @@
xref: MetaCyc:XYLONATE-DEHYDRATASE-RXN
xref: RHEA:19157
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.82
+property_value: skos:exactMatch RHEA:19157
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050402
@@ -320149,6 +333211,9 @@
xref: MetaCyc:RXN-19753
xref: RHEA:18341
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.68
+property_value: skos:exactMatch RHEA:18341
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050403
@@ -320166,6 +333231,9 @@
xref: MetaCyc:RXN-4723
xref: RHEA:23224
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.203
+property_value: skos:exactMatch RHEA:23224
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050404
@@ -320181,6 +333249,9 @@
xref: MetaCyc:ZEATIN-O-BETA-D-XYLOSYLTRANSFERASE-RXN
xref: RHEA:14721
is_a: GO:0035252 ! UDP-xylosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.40
+property_value: skos:exactMatch RHEA:14721
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050405
@@ -320218,6 +333289,9 @@
xref: MetaCyc:ACETYL-COA-CARBOXYLASE-PHOSPHATASE-RXN
xref: RHEA:17125
is_a: GO:0004721 ! phosphoprotein phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.44
+property_value: skos:exactMatch RHEA:17125
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050407
@@ -320239,6 +333313,8 @@
xref: EC:3.1.3.42
xref: MetaCyc:GLYCOGEN-SYNTHASE-D-PHOSPHATASE-RXN
is_a: GO:0004721 ! phosphoprotein phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.42
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050408
@@ -320251,6 +333327,8 @@
xref: EC:3.1.3.49
xref: MetaCyc:PYRUVATE-KINASE-PHOSPHATASE-RXN
is_a: GO:0004721 ! phosphoprotein phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.49
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050409
@@ -320266,6 +333344,9 @@
xref: RHEA:19505
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0052636 ! arabinosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.34
+property_value: skos:exactMatch RHEA:19505
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050410
@@ -320281,6 +333362,8 @@
xref: MetaCyc:3-OXOLAURATE-DECARBOXYLASE-RXN
xref: RHEA:13385
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.56
+property_value: skos:exactMatch RHEA:13385
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -320311,6 +333394,9 @@
xref: MetaCyc:CINNAMATE-GLUCOSYLTRANSFERASE-RXN
xref: RHEA:13437
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.177
+property_value: skos:exactMatch RHEA:13437
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050413
@@ -320325,6 +333411,9 @@
xref: MetaCyc:D-ALANINE-HYDROXYMETHYLTRANSFERASE-RXN
xref: RHEA:10064
is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity
+property_value: skos:exactMatch EC:2.1.2.7
+property_value: skos:exactMatch RHEA:10064
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050414
@@ -320337,6 +333426,9 @@
xref: MetaCyc:FORMIMINOASPARTATE-DEIMINASE-RXN
xref: RHEA:13661
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.5
+property_value: skos:exactMatch RHEA:13661
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050415
@@ -320353,6 +333445,9 @@
xref: MetaCyc:FORMIMINOGLUTAMASE-RXN
xref: RHEA:22492
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.8
+property_value: skos:exactMatch RHEA:22492
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050416
@@ -320366,6 +333461,9 @@
xref: MetaCyc:FORMIMINOGLUTAMATE-DEIMINASE-RXN
xref: RHEA:22832
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.13
+property_value: skos:exactMatch RHEA:22832
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050417
@@ -320379,7 +333477,11 @@
synonym: "L-glutamine(L-asparagine) amidohydrolase activity" RELATED [EC:3.5.1.38]
xref: EC:3.5.1.38
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:broadMatch MetaCyc:ASPARAGHYD-RXN
+property_value: skos:broadMatch MetaCyc:GLUTAMIN-RXN
+property_value: skos:exactMatch EC:3.5.1.38
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050418
@@ -320393,6 +333495,9 @@
xref: MetaCyc:HYDROXYLAMINE-REDUCTASE-RXN
xref: RHEA:22052
is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors
+property_value: skos:exactMatch EC:1.7.99.1
+property_value: skos:exactMatch RHEA:22052
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050419
@@ -320407,7 +333512,10 @@
xref: MetaCyc:HYDROXYMANDELONITRILE-LYASE-RXN
xref: RHEA:15977
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.11
+property_value: skos:exactMatch RHEA:15977
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050420
@@ -320419,6 +333527,9 @@
xref: MetaCyc:MALTOSE-SYNTHASE-RXN
xref: RHEA:22320
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.139
+property_value: skos:exactMatch RHEA:22320
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050421
@@ -320442,6 +333553,8 @@
xref: RHEA:15233
is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor
is_a: GO:0098809 ! nitrite reductase activity
+property_value: skos:exactMatch EC:1.7.2.1
+property_value: skos:exactMatch RHEA:15233
[Term]
id: GO:0050422
@@ -320455,6 +333568,9 @@
xref: MetaCyc:STRICTOSIDINE-BETA-GLUCOSIDASE-RXN
xref: RHEA:12917
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.105
+property_value: skos:exactMatch RHEA:12917
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050423
@@ -320470,6 +333586,9 @@
xref: MetaCyc:THIAMIN-OXIDASE-RXN
xref: RHEA:21280
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.23
+property_value: skos:exactMatch RHEA:21280
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050424
@@ -320557,11 +333676,14 @@
[Term]
id: GO:0050429
-name: calcium-dependent phospholipase C activity
+name: obsolete calcium-dependent phospholipase C activity
namespace: molecular_function
-def: "Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate. This reaction requires Ca2+." [PMID:25769297, PMID:9426125]
-is_a: GO:0004629 ! phospholipase C activity
+def: "OBSOLETE. Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate. This reaction requires Ca2+." [PMID:25769297, PMID:9426125]
+comment: This term was made obsolete because it represents information outside the scope of GO.
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23316" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31061" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0140324
[Term]
id: GO:0050431
@@ -320619,7 +333741,7 @@
synonym: "amyloid-beta metabolism" EXACT []
synonym: "beta-amyloid metabolic process" EXACT []
synonym: "beta-amyloid metabolism" EXACT []
-is_a: GO:0043603 ! amide metabolic process
+is_a: GO:0008152 ! metabolic process
[Term]
id: GO:0050436
@@ -320643,6 +333765,9 @@
xref: MetaCyc:4.2.3.10-RXN
xref: RHEA:20565
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.10
+property_value: skos:exactMatch RHEA:20565
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050438
@@ -320659,6 +333784,9 @@
xref: MetaCyc:2-ETHYLMALATE-SYNTHASE-RXN
xref: RHEA:23040
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.6
+property_value: skos:exactMatch RHEA:23040
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050439
@@ -320676,6 +333804,9 @@
xref: MetaCyc:2-HYDROXY-3-OXOADIPATE-SYNTHASE-RXN
xref: RHEA:14341
is_a: GO:0016744 ! transketolase or transaldolase activity
+property_value: skos:exactMatch EC:2.2.1.5
+property_value: skos:exactMatch RHEA:14341
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050440
@@ -320692,6 +333823,9 @@
xref: MetaCyc:2-METHYLCITRATE-SYNTHASE-RXN
xref: RHEA:23780
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.5
+property_value: skos:exactMatch RHEA:23780
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050441
@@ -320706,6 +333840,9 @@
xref: MetaCyc:3-ETHYLMALATE-SYNTHASE-RXN
xref: RHEA:10500
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.7
+property_value: skos:exactMatch RHEA:10500
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050442
@@ -320722,6 +333859,9 @@
xref: MetaCyc:3-PROPYLMALATE-SYNTHASE-RXN
xref: RHEA:14457
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.12
+property_value: skos:exactMatch RHEA:14457
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050444
@@ -320749,6 +333889,9 @@
xref: MetaCyc:ASPARAGUSATE-REDUCTASE-NADH-RXN
xref: RHEA:14881
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:exactMatch EC:1.8.1.11
+property_value: skos:exactMatch RHEA:14881
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050446
@@ -320781,6 +333924,9 @@
xref: RHEA:16269
xref: UM-BBD_reactionID:r0808
is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.7.1.6
+property_value: skos:exactMatch RHEA:16269
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050447
@@ -320801,6 +333947,9 @@
xref: MetaCyc:BETA-9-CYTOKININ-ALANINE-SYNTHASE-RXN
xref: RHEA:17333
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.50
+property_value: skos:exactMatch RHEA:17333
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050448
@@ -320817,6 +333966,9 @@
xref: MetaCyc:BETA-CYCLOPIAZONATE-DEHYDROGENASE-RXN
xref: RHEA:14525
is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond
+property_value: skos:exactMatch EC:1.21.99.1
+property_value: skos:exactMatch RHEA:14525
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050449
@@ -320831,6 +333983,9 @@
xref: MetaCyc:CASBENE-SYNTHASE-RXN
xref: RHEA:14901
is_a: GO:0010333 ! terpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.8
+property_value: skos:exactMatch RHEA:14901
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050450
@@ -320864,8 +334019,11 @@
xref: RHEA:14705
is_a: GO:0015036 ! disulfide oxidoreductase activity
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:exactMatch EC:1.8.1.14
+property_value: skos:exactMatch RHEA:14705
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25492" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050452
@@ -320883,7 +334041,10 @@
xref: MetaCyc:COA-GLUTATHIONE-REDUCTASE-NADPH-RXN
xref: RHEA:14617
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:exactMatch EC:1.8.1.10
+property_value: skos:exactMatch RHEA:14617
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050453
@@ -320910,6 +334071,9 @@
xref: MetaCyc:COENZYME-F420-HYDROGENASE-RXN
xref: RHEA:23760
is_a: GO:0046995 ! oxidoreductase activity, acting on hydrogen as donor, with other known acceptors
+property_value: skos:exactMatch EC:1.12.98.1
+property_value: skos:exactMatch RHEA:23760
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050455
@@ -320923,6 +334087,9 @@
xref: MetaCyc:COLUMBAMINE-OXIDASE-RXN
xref: RHEA:23564
is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
+property_value: skos:exactMatch EC:1.21.3.2
+property_value: skos:exactMatch RHEA:23564
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050456
@@ -320941,6 +334108,9 @@
xref: MetaCyc:CYSTINE-REDUCTASE-NADH-RXN
xref: RHEA:20597
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:exactMatch EC:1.8.1.6
+property_value: skos:exactMatch RHEA:20597
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050457
@@ -320956,6 +334126,9 @@
xref: MetaCyc:DECYLCITRATE-SYNTHASE-RXN
xref: RHEA:16605
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.2
+property_value: skos:exactMatch RHEA:16605
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050458
@@ -320971,6 +334144,9 @@
xref: MetaCyc:DECYLHOMOCITRATE-SYNTHASE-RXN
xref: RHEA:10364
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.4
+property_value: skos:exactMatch RHEA:10364
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050459
@@ -320988,6 +334164,9 @@
xref: Reactome:R-HSA-5696415 "PXLP-K278-ETNPPL tetramer hydrolyses PETA"
xref: RHEA:17889
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.2
+property_value: skos:exactMatch RHEA:17889
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050460
@@ -321005,6 +334184,9 @@
xref: MetaCyc:HYDROXYLAMINE-REDUCTASE-NADH-RXN
xref: RHEA:20581
is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.7.1.10
+property_value: skos:exactMatch RHEA:20581
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050461
@@ -321020,12 +334202,14 @@
xref: MetaCyc:RXN-7461
xref: RHEA:12693
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.52
+property_value: skos:exactMatch RHEA:12693
[Term]
id: GO:0050462
name: N-acetylneuraminate synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate." [EC:2.5.1.56, MetaCyc:N-ACETYLNEURAMINATE-SYNTHASE-RXN]
+def: "Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate." [EC:2.5.1.56]
synonym: "(NANA)condensing enzyme activity" RELATED [EC:2.5.1.56]
synonym: "N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating) activity" RELATED [EC:2.5.1.56]
synonym: "N-acetylneuraminic acid synthase activity" RELATED [EC:2.5.1.56]
@@ -321035,6 +334219,9 @@
xref: MetaCyc:N-ACETYLNEURAMINATE-SYNTHASE-RXN
xref: RHEA:19273
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.56
+property_value: skos:exactMatch RHEA:19273
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050463
@@ -321054,6 +334241,7 @@
xref: EC:1.7.1.2
is_a: GO:0008940 ! nitrate reductase activity
is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.7.1.2
[Term]
id: GO:0050464
@@ -321074,6 +334262,8 @@
xref: MetaCyc:NITRATE-REDUCTASE-NADPH-RXN
xref: RHEA:19061
is_a: GO:0050463 ! nitrate reductase [NAD(P)H] activity
+property_value: skos:exactMatch EC:1.7.1.3
+property_value: skos:exactMatch RHEA:19061
[Term]
id: GO:0050465
@@ -321087,7 +334277,12 @@
synonym: "NAD(P)H:4-nitroquinoline-N-oxide oxidoreductase activity" RELATED [EC:1.7.1.9]
xref: EC:1.7.1.9
xref: MetaCyc:1.7.1.9-RXN
+xref: RHEA:22476
+xref: RHEA:22480
is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.7.1.9
+property_value: skos:narrowMatch RHEA:22476
+property_value: skos:narrowMatch RHEA:22480
[Term]
id: GO:0050466
@@ -321112,6 +334307,9 @@
xref: MetaCyc:PENTALENENE-SYNTHASE-RXN
xref: RHEA:18081
is_a: GO:0010334 ! sesquiterpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.7
+property_value: skos:exactMatch RHEA:18081
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050468
@@ -321128,7 +334326,10 @@
xref: MetaCyc:RETICULINE-OXIDASE-RXN
xref: RHEA:19885
is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
+property_value: skos:exactMatch EC:1.21.3.3
+property_value: skos:exactMatch RHEA:19885
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28942" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050469
@@ -321142,6 +334343,9 @@
xref: MetaCyc:4.2.3.11-RXN
xref: RHEA:19565
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.11
+property_value: skos:exactMatch RHEA:19565
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050470
@@ -321155,6 +334359,9 @@
xref: RHEA:11864
xref: UM-BBD_enzymeID:r1378
is_a: GO:0046997 ! oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor
+property_value: skos:exactMatch EC:1.5.8.2
+property_value: skos:exactMatch RHEA:11864
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050471
@@ -321171,6 +334378,8 @@
xref: MetaCyc:RXN-7541
xref: RHEA:11496
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.53
+property_value: skos:exactMatch RHEA:11496
[Term]
id: GO:0050472
@@ -321183,6 +334392,9 @@
xref: MetaCyc:ZEATIN-REDUCTASE-RXN
xref: RHEA:12757
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.69
+property_value: skos:exactMatch RHEA:12757
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050473
@@ -321208,6 +334420,9 @@
xref: Reactome:R-HSA-9026003 "ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3"
xref: RHEA:16869
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.33
+property_value: skos:exactMatch RHEA:16869
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050474
@@ -321222,7 +334437,10 @@
xref: MetaCyc:S-NORLAUDANOSOLINE-SYNTHASE-RXN
xref: RHEA:16173
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch EC:3.5.99.14
+property_value: skos:exactMatch RHEA:16173
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28647" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050476
@@ -321237,6 +334455,9 @@
xref: MetaCyc:4.1.1.78-RXN
xref: RHEA:17733
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.78
+property_value: skos:exactMatch RHEA:17733
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050477
@@ -321250,6 +334471,9 @@
xref: MetaCyc:ACYL-LYSINE-DEACYLASE-RXN
xref: RHEA:24548
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.17
+property_value: skos:exactMatch RHEA:24548
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050478
@@ -321278,6 +334502,9 @@
xref: Reactome:R-HSA-5696119 "AGMO cleaves alkylglycerol into fatty aldehyde and glycerol"
xref: RHEA:36255
is_a: GO:0016714 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.16.5
+property_value: skos:exactMatch RHEA:36255
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050480
@@ -321293,6 +334520,9 @@
xref: MetaCyc:IMIDAZOLONEPROPIONASE-RXN
xref: RHEA:23660
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.7
+property_value: skos:exactMatch RHEA:23660
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050481
@@ -321307,6 +334537,9 @@
xref: MetaCyc:MANDELATE-4-MONOOXYGENASE-RXN
xref: RHEA:21716
is_a: GO:0016714 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.16.6
+property_value: skos:exactMatch RHEA:21716
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050482
@@ -321353,6 +334586,8 @@
synonym: "oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulphide as acceptor" EXACT []
xref: EC:1.21.4.-
is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond
+property_value: skos:exactMatch EC:1.21.4.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050486
@@ -321362,7 +334597,9 @@
synonym: "intramolecular transferase activity, transferring hydroxy groups" EXACT []
xref: EC:5.4.4.-
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.4.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26155" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050487
@@ -321377,6 +334614,9 @@
xref: MetaCyc:RXN-2364
xref: RHEA:24204
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
+property_value: skos:exactMatch EC:2.3.3.15
+property_value: skos:exactMatch RHEA:24204
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050488
@@ -321398,6 +334638,9 @@
xref: MetaCyc:14-LACTONASE-RXN
xref: RHEA:12745
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.25
+property_value: skos:exactMatch RHEA:12745
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050491
@@ -321410,6 +334653,9 @@
xref: MetaCyc:1.1.1.260-RXN
xref: RHEA:24484
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.260
+property_value: skos:exactMatch RHEA:24484
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050492
@@ -321420,6 +334666,8 @@
xref: EC:1.1.1.261
xref: MetaCyc:1.1.1.261-RXN
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.261
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050493
@@ -321475,6 +334723,8 @@
synonym: "transferase activity, transferring alkylthio groups" EXACT []
xref: EC:2.8.4.-
is_a: GO:0016782 ! transferase activity, transferring sulphur-containing groups
+property_value: skos:exactMatch EC:2.8.4.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050498
@@ -321483,6 +334733,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and the latter donor is dehydrogenated." [EC:1.14.20.-]
xref: EC:1.14.20.-
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.20.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
[Term]
@@ -321492,6 +334744,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a NAD(P)+ to NAD(P)H." [GOC:mah]
xref: EC:1.20.1.-
is_a: GO:0030613 ! oxidoreductase activity, acting on phosphorus or arsenic in donors
+property_value: skos:exactMatch EC:1.20.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050500
@@ -321505,6 +334759,9 @@
xref: MetaCyc:2.4.1.211-RXN
xref: RHEA:20285
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.211
+property_value: skos:exactMatch RHEA:20285
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050501
@@ -321518,10 +334775,13 @@
synonym: "spHAS" RELATED [EC:2.4.1.212]
xref: EC:2.4.1.212
xref: MetaCyc:2.4.1.212-RXN
-xref: Reactome:R-HSA-2160851 "HAS1,2,3 mediate the polymerization and export of HA"
+xref: Reactome:R-HSA-2160851 "HAS1,2,3 mediate the polymerization of HA"
xref: RHEA:12528
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.212
+property_value: skos:exactMatch RHEA:12528
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050502
@@ -321536,6 +334796,9 @@
xref: MetaCyc:RXN-4735
xref: RHEA:20681
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.215
+property_value: skos:exactMatch RHEA:20681
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050503
@@ -321547,6 +334810,9 @@
xref: MetaCyc:2.4.1.216-RXN
xref: RHEA:20864
is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity
+property_value: skos:exactMatch EC:2.4.1.216
+property_value: skos:exactMatch RHEA:20864
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050504
@@ -321560,6 +334826,9 @@
xref: MetaCyc:2.4.1.217-RXN
xref: RHEA:13537
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.217
+property_value: skos:exactMatch RHEA:13537
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050505
@@ -321575,6 +334844,9 @@
xref: MetaCyc:2.4.1.218-RXN
xref: RHEA:12560
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.218
+property_value: skos:exactMatch RHEA:12560
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050506
@@ -321590,6 +334862,9 @@
xref: MetaCyc:2.4.1.219-RXN
xref: RHEA:19385
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.219
+property_value: skos:exactMatch RHEA:19385
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050507
@@ -321603,6 +334878,9 @@
xref: MetaCyc:2.4.1.220-RXN
xref: RHEA:12004
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.220
+property_value: skos:exactMatch RHEA:12004
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050508
@@ -321615,12 +334893,18 @@
synonym: "UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity" RELATED [EC:2.4.1.224]
xref: EC:2.4.1.224
xref: MetaCyc:2.4.1.224-RXN
-xref: Reactome:R-HSA-2022851 "EXT1:EXT2 transfers GlcNAc to the heparan chain"
+xref: Reactome:R-HSA-2022851 "EXT1:EXT2 transfer GlcNAc to the heparan chain"
+xref: Reactome:R-HSA-2022919 "EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue"
xref: Reactome:R-HSA-3656254 "Defective EXT2 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain"
xref: Reactome:R-HSA-3656261 "Defective EXT1 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain"
+xref: Reactome:R-HSA-9036283 "Defective EXT1 (in EXT1:EXT2) does not transfer GlcNAc to the terminal GlcA residue"
+xref: Reactome:R-HSA-9036290 "Defective EXT2 (in EXT1:EXT2) does not transfer GlcNAc to heparan"
xref: RHEA:16213
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.224
+property_value: skos:exactMatch RHEA:16213
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28762" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050509
@@ -321633,7 +334917,7 @@
synonym: "UDP-alpha-D-glucuronate:N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 4-beta-glucuronosyltransferase activity" RELATED [EC:2.4.1.225]
xref: EC:2.4.1.225
xref: MetaCyc:2.4.1.225-RXN
-xref: Reactome:R-HSA-2022856 "EXT1:EXT2 transfers GlcA to heparan"
+xref: Reactome:R-HSA-2022856 "EXT1:EXT2 transfers GlcNAc to heparan"
xref: Reactome:R-HSA-2076392 "EXT1:EXT2 transfers GlcA to heparan"
xref: Reactome:R-HSA-3656257 "Defective EXT1 (in EXT1:EXT2) does not transfer GlcA to heparan"
xref: Reactome:R-HSA-3656267 "Defective EXT2 (in EXT1:EXT2) does not transfer GlcA to heparan"
@@ -321641,7 +334925,10 @@
xref: Reactome:R-HSA-9036289 "Defective EXT2 (in EXT1:EXT2) does not transfer GlcA to heparan"
xref: RHEA:20908
is_a: GO:0015020 ! glucuronosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.225
+property_value: skos:exactMatch RHEA:20908
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28762" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050510
@@ -321653,9 +334940,12 @@
synonym: "N-acetylgalactosaminyl-proteoglycan 3-b-glucuronosyltransferase activity" EXACT []
xref: EC:2.4.1.226
xref: MetaCyc:RXN-16324
-xref: Reactome:R-HSA-1971491 "Chondroitin polymerase complex transfers GlcA to CS chain"
+xref: Reactome:R-HSA-1971491 "CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin"
xref: Reactome:R-HSA-3595178 "Defective CHSY1 does not transfer GlcA to chondroitin"
+xref: Reactome:R-HSA-9632034 "CHSY1 transfers GlcA to chondroitin"
is_a: GO:0015020 ! glucuronosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.226
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050511
@@ -321670,6 +334960,8 @@
xref: MetaCyc:RXN-8976
xref: RHEA:23192
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:broadMatch EC:2.4.1.227
+property_value: skos:exactMatch RHEA:23192
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -321689,6 +334981,9 @@
xref: Reactome:R-HSA-9846477 "A4GALT transfers galactose to LacCer"
xref: RHEA:11924
is_a: GO:0035250 ! UDP-galactosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.228
+property_value: skos:exactMatch RHEA:11924
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050513
@@ -321703,17 +334998,23 @@
xref: MetaCyc:2.4.2.38-RXN
xref: RHEA:10612
is_a: GO:0035252 ! UDP-xylosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.38
+property_value: skos:exactMatch RHEA:10612
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050514
name: homospermidine synthase (spermidine-specific) activity
namespace: molecular_function
-def: "Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine." [EC:2.5.1.45, MetaCyc:2.5.1.45-RXN]
+def: "Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine." [EC:2.5.1.45]
synonym: "spermidine:putrescine 4-aminobutyltransferase (propane-1,3-diamine-forming)" RELATED [EC:2.5.1.45]
xref: EC:2.5.1.45
xref: MetaCyc:2.5.1.45-RXN
xref: RHEA:11236
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.45
+property_value: skos:exactMatch RHEA:11236
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050515
@@ -321732,6 +335033,9 @@
xref: RHEA:18437
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.148
+property_value: skos:exactMatch RHEA:18437
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050516
@@ -321770,6 +335074,9 @@
xref: MetaCyc:2.7.7.60-RXN
xref: RHEA:13429
is_a: GO:0070567 ! cytidylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.60
+property_value: skos:exactMatch RHEA:13429
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050519
@@ -321785,6 +335092,9 @@
xref: MetaCyc:2.7.7.61-RXN
xref: RHEA:16333
is_a: GO:0016779 ! nucleotidyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.61
+property_value: skos:exactMatch RHEA:16333
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050520
@@ -321800,6 +335110,9 @@
xref: MetaCyc:2.7.8.24-RXN
xref: RHEA:14597
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.24
+property_value: skos:exactMatch RHEA:14597
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050521
@@ -321816,6 +335129,8 @@
xref: RHEA:11668
is_a: GO:0016301 ! kinase activity
is_a: GO:0016781 ! phosphotransferase activity, paired acceptors
+property_value: skos:exactMatch EC:2.7.9.4
+property_value: skos:exactMatch RHEA:11668
[Term]
id: GO:0050522
@@ -321853,6 +335168,9 @@
xref: RHEA:12532
xref: UM-BBD_reactionID:r0356
is_a: GO:0050497 ! alkylthioltransferase activity
+property_value: skos:exactMatch EC:2.8.4.1
+property_value: skos:exactMatch RHEA:12532
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050525
@@ -321863,6 +335181,8 @@
xref: EC:3.1.1.74
xref: MetaCyc:3.1.1.74-RXN
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.74
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050526
@@ -321881,6 +335201,9 @@
xref: MetaCyc:3.1.1.75-RXN
xref: RHEA:11248
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.75
+property_value: skos:exactMatch RHEA:11248
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050527
@@ -321901,6 +335224,8 @@
xref: EC:3.1.1.76
xref: MetaCyc:3.1.1.76-RXN
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.76
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050528
@@ -321911,6 +335236,9 @@
xref: MetaCyc:3.1.1.77-RXN
xref: RHEA:12032
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.77
+property_value: skos:exactMatch RHEA:12032
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050529
@@ -321925,6 +335253,9 @@
xref: MetaCyc:3.1.1.78-RXN
xref: RHEA:17501
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.78
+property_value: skos:exactMatch RHEA:17501
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050530
@@ -321939,6 +335270,9 @@
xref: MetaCyc:3.1.3.69-RXN
xref: RHEA:22652
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.69
+property_value: skos:exactMatch RHEA:22652
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050531
@@ -321951,6 +335285,9 @@
xref: MetaCyc:3.1.3.70-RXN
xref: RHEA:19309
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.70
+property_value: skos:exactMatch RHEA:19309
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050532
@@ -321966,6 +335303,9 @@
xref: MetaCyc:R229-RXN
xref: RHEA:23416
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.71
+property_value: skos:exactMatch RHEA:23416
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050533
@@ -321978,7 +335318,10 @@
xref: MetaCyc:3.1.3.72-RXN
xref: RHEA:13001
is_a: GO:0004446 ! inositol hexakisphosphate phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.72
+property_value: skos:exactMatch RHEA:13001
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25949" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050534
@@ -321990,6 +335333,7 @@
xref: EC:3.2.1.144
xref: MetaCyc:RXN-11916
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.144
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30557" xsd:anyURI
[Term]
@@ -322003,7 +335347,10 @@
xref: MetaCyc:3.2.1.149-RXN
xref: RHEA:24480
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.149
+property_value: skos:exactMatch RHEA:24480
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050536
@@ -322017,6 +335364,9 @@
xref: MetaCyc:3.5.1.85-RXN
xref: RHEA:23952
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.85
+property_value: skos:exactMatch RHEA:23952
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050537
@@ -322030,6 +335380,9 @@
xref: MetaCyc:3.5.1.86-RXN
xref: RHEA:22876
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.86
+property_value: skos:exactMatch RHEA:22876
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050538
@@ -322042,6 +335395,9 @@
xref: MetaCyc:3.5.1.87-RXN
xref: RHEA:17581
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.87
+property_value: skos:exactMatch RHEA:17581
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050539
@@ -322057,6 +335413,9 @@
xref: MetaCyc:3.5.2.16-RXN
xref: RHEA:24476
is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
+property_value: skos:exactMatch EC:3.5.2.16
+property_value: skos:exactMatch RHEA:24476
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050540
@@ -322069,6 +335428,9 @@
xref: MetaCyc:3.5.99.5-RXN
xref: RHEA:20996
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.99.5
+property_value: skos:exactMatch RHEA:20996
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050541
@@ -322117,6 +335479,9 @@
xref: MetaCyc:R231-RXN
xref: RHEA:20948
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.79
+property_value: skos:exactMatch RHEA:20948
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050546
@@ -322130,6 +335495,9 @@
xref: MetaCyc:4.1.1.80-RXN
xref: RHEA:18697
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.80
+property_value: skos:exactMatch RHEA:18697
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050547
@@ -322142,9 +335510,16 @@
xref: EC:4.1.2.61
xref: KEGG_REACTION:R12566
xref: MetaCyc:RXN-21004
+xref: RHEA:36307
xref: RHEA:62412
+xref: RHEA:62416
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.61
+property_value: skos:exactMatch RHEA:62412
+property_value: skos:narrowMatch RHEA:36307
+property_value: skos:narrowMatch RHEA:62416
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27660" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050548
@@ -322172,6 +335547,9 @@
xref: RHEA:18197
xref: UM-BBD_reactionID:r1029
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.103
+property_value: skos:exactMatch RHEA:18197
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050550
@@ -322182,7 +335560,31 @@
synonym: "alpha-pinene synthase activity" NARROW [EC:4.2.3.119]
synonym: "beta-geraniolene synthase activity" RELATED [EC:4.2.3.120]
synonym: "beta-pinene synthase activity" NARROW [EC:4.2.3.120]
+xref: EC:4.2.3.119
+xref: EC:4.2.3.120
+xref: EC:4.2.3.121
+xref: EC:4.2.3.122
+xref: MetaCyc:RXN-5106
+xref: MetaCyc:RXN-5107
+xref: MetaCyc:RXN-8563
+xref: MetaCyc:RXN-8564
+xref: RHEA:25488
+xref: RHEA:25496
+xref: RHEA:32575
+xref: RHEA:32579
is_a: GO:0010333 ! terpene synthase activity
+property_value: skos:narrowMatch EC:4.2.3.119
+property_value: skos:narrowMatch EC:4.2.3.120
+property_value: skos:narrowMatch EC:4.2.3.121
+property_value: skos:narrowMatch EC:4.2.3.122
+property_value: skos:narrowMatch MetaCyc:RXN-5106
+property_value: skos:narrowMatch MetaCyc:RXN-5107
+property_value: skos:narrowMatch MetaCyc:RXN-8563
+property_value: skos:narrowMatch MetaCyc:RXN-8564
+property_value: skos:narrowMatch RHEA:25488
+property_value: skos:narrowMatch RHEA:25496
+property_value: skos:narrowMatch RHEA:32575
+property_value: skos:narrowMatch RHEA:32579
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26207" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
@@ -322197,6 +335599,9 @@
xref: MetaCyc:RXN-5110
xref: RHEA:16965
is_a: GO:0010333 ! terpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.15
+property_value: skos:exactMatch RHEA:16965
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050552
@@ -322212,6 +335617,9 @@
xref: MetaCyc:4.2.3.16-RXN
xref: RHEA:12869
is_a: GO:0010333 ! terpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.16
+property_value: skos:exactMatch RHEA:12869
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050553
@@ -322226,6 +335634,9 @@
xref: MetaCyc:4.2.3.17-RXN
xref: RHEA:20912
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.17
+property_value: skos:exactMatch RHEA:20912
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050554
@@ -322240,6 +335651,9 @@
xref: MetaCyc:4.2.3.18-RXN
xref: RHEA:13873
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.18
+property_value: skos:exactMatch RHEA:13873
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050555
@@ -322259,10 +335673,16 @@
synonym: "epoxypropyl:CoM transferase activity" RELATED [EC:4.4.1.23]
xref: EC:4.4.1.23
xref: MetaCyc:4.2.99.19-RXN
+xref: RHEA:19421
+xref: RHEA:20904
xref: UM-BBD_enzymeID:r0851
xref: UM-BBD_enzymeID:r0858
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.23
+property_value: skos:narrowMatch RHEA:19421
+property_value: skos:narrowMatch RHEA:20904
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050556
@@ -322276,7 +335696,10 @@
xref: MetaCyc:4.3.3.3-RXN
xref: RHEA:21756
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch EC:3.5.99.15
+property_value: skos:exactMatch RHEA:21756
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28647" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050557
@@ -322290,7 +335713,10 @@
xref: MetaCyc:4.3.3.4-RXN
xref: RHEA:12296
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch EC:3.5.99.16
+property_value: skos:exactMatch RHEA:12296
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28647" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050558
@@ -322303,6 +335729,8 @@
xref: MetaCyc:5.1.3.21-RXN
xref: RHEA:21228
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.21
+property_value: skos:exactMatch RHEA:21228
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
[Term]
@@ -322317,6 +335745,9 @@
xref: MetaCyc:RXN-4861
xref: RHEA:24316
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.12
+property_value: skos:exactMatch RHEA:24316
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050560
@@ -322330,6 +335761,9 @@
xref: MetaCyc:6.1.1.23-RXN
xref: RHEA:18349
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.23
+property_value: skos:exactMatch RHEA:18349
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050561
@@ -322343,6 +335777,9 @@
xref: MetaCyc:6.1.1.24-RXN
xref: RHEA:18397
is_a: GO:0004812 ! aminoacyl-tRNA ligase activity
+property_value: skos:exactMatch EC:6.1.1.24
+property_value: skos:exactMatch RHEA:18397
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050562
@@ -322366,7 +335803,12 @@
synonym: "trans-feruloyl-CoA synthetase activity" RELATED [EC:6.2.1.34]
xref: EC:6.2.1.34
xref: MetaCyc:6.2.1.34-RXN
+xref: RHEA:19389
+xref: RHEA:36251
is_a: GO:0016405 ! CoA-ligase activity
+property_value: skos:exactMatch EC:6.2.1.34
+property_value: skos:narrowMatch RHEA:19389
+property_value: skos:narrowMatch RHEA:36251
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
created_by: hjd
creation_date: 2020-07-30T15:20:51Z
@@ -322386,7 +335828,10 @@
xref: MetaCyc:6.3.2.26-RXN
xref: RHEA:23196
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.26
+property_value: skos:exactMatch RHEA:23196
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29594" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050565
@@ -322395,9 +335840,15 @@
def: "Catalysis of the reaction: ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine = aerobactin + AMP + diphosphate + H+." [RHEA:32167]
synonym: "citrate:6-N-acetyl-6-N-hydroxy-L-lysine ligase (ADP-forming)" EXACT []
synonym: "citrate:N6-acetyl-N6-hydroxy-L-lysine ligase (ADP-forming)" EXACT []
+xref: EC:6.3.2.39
+xref: MetaCyc:RXN-13056
xref: RHEA:32167
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.39
+property_value: skos:exactMatch MetaCyc:RXN-13056
+property_value: skos:exactMatch RHEA:32167
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23472" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0050566
@@ -322418,6 +335869,9 @@
xref: Wikipedia:Asparaginyl-tRNA_synthase_(glutamine-hydrolysing)
is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:6.3.5.6
+property_value: skos:exactMatch RHEA:14513
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050567
@@ -322440,6 +335894,9 @@
xref: Wikipedia:Glutaminyl-tRNA_synthase_(glutamine-hydrolysing)
is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:6.3.5.7
+property_value: skos:exactMatch RHEA:17521
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050568
@@ -322457,6 +335914,9 @@
xref: RHEA:16441
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:3.5.1.44
+property_value: skos:exactMatch RHEA:16441
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050569
@@ -322470,6 +335930,9 @@
xref: MetaCyc:GLYCOLALD-DEHYDROG-RXN
xref: RHEA:20001
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.21
+property_value: skos:exactMatch RHEA:20001
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050570
@@ -322483,7 +335946,10 @@
xref: MetaCyc:RXN-13179
xref: RHEA:32275
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.262
+property_value: skos:exactMatch RHEA:32275
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25977" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050571
@@ -322495,9 +335961,11 @@
xref: EC:1.1.1.263
xref: KEGG_REACTION:R05682
xref: MetaCyc:1.1.1.263-RXN
-xref: Reactome:R-HSA-9773976 "AKR1E2 reduces 1,5-aF to 1,5-aG"
xref: RHEA:20665
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.263
+property_value: skos:exactMatch RHEA:20665
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050572
@@ -322507,8 +335975,12 @@
synonym: "L-idonate:NAD(P)+ oxidoreductase activity" RELATED [EC:1.1.1.264]
xref: EC:1.1.1.264
xref: MetaCyc:1.1.1.264-RXN
+xref: RHEA:21176
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.264
+property_value: skos:narrowMatch RHEA:21176
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27573" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050573
@@ -322522,6 +335994,9 @@
xref: MetaCyc:1.1.1.266-RXN
xref: RHEA:36583
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.266
+property_value: skos:exactMatch RHEA:36583
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050574
@@ -322536,6 +336011,9 @@
xref: RHEA:13249
xref: UM-BBD_reactionID:r0852
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.268
+property_value: skos:exactMatch RHEA:13249
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050575
@@ -322550,6 +336028,9 @@
xref: RHEA:21052
xref: UM-BBD_reactionID:r0853
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.269
+property_value: skos:exactMatch RHEA:21052
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050577
@@ -322565,6 +336046,9 @@
xref: RHEA:18885
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
relationship: part_of GO:0042350 ! GDP-L-fucose biosynthetic process
+property_value: skos:exactMatch EC:1.1.1.271
+property_value: skos:exactMatch RHEA:18885
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050578
@@ -322580,6 +336064,8 @@
xref: RHEA:35735
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
is_a: GO:0033719 ! (2R)-oxo-acid reductase activity
+property_value: skos:exactMatch EC:1.1.1.272
+property_value: skos:exactMatch RHEA:35735
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30138" xsd:anyURI
[Term]
@@ -322593,6 +336079,9 @@
xref: MetaCyc:1.1.1.273-RXN
xref: RHEA:20029
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.273
+property_value: skos:exactMatch RHEA:20029
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050580
@@ -322606,6 +336095,9 @@
xref: MetaCyc:1.1.1.274-RXN
xref: RHEA:23828
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.274
+property_value: skos:exactMatch RHEA:23828
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050581
@@ -322620,6 +336112,9 @@
xref: MetaCyc:1.1.3.40-RXN
xref: RHEA:18513
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.40
+property_value: skos:exactMatch RHEA:18513
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050582
@@ -322629,7 +336124,12 @@
synonym: "xylitol:oxygen oxidoreductase activity" RELATED [EC:1.1.3.41]
xref: EC:1.1.3.41
xref: MetaCyc:1.1.3.41-RXN
+xref: RHEA:22308
+xref: RHEA:25908
is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.1.3.41
+property_value: skos:narrowMatch RHEA:22308
+property_value: skos:narrowMatch RHEA:25908
[Term]
id: GO:0050583
@@ -322643,6 +336143,9 @@
xref: MetaCyc:1.12.1.3-RXN
xref: RHEA:18637
is_a: GO:0016696 ! oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.12.1.3
+property_value: skos:exactMatch RHEA:18637
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050584
@@ -322657,6 +336160,9 @@
xref: MetaCyc:1.13.11.45-RXN
xref: RHEA:18993
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.45
+property_value: skos:exactMatch RHEA:18993
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050585
@@ -322670,6 +336176,9 @@
xref: Reactome:R-HSA-9856718 "HPDL dioxygenates HPPA"
xref: RHEA:21376
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.46
+property_value: skos:exactMatch RHEA:21376
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050586
@@ -322686,6 +336195,9 @@
xref: MetaCyc:1.13.11.48-RXN
xref: RHEA:21572
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.48
+property_value: skos:exactMatch RHEA:21572
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050587
@@ -322701,6 +336213,9 @@
xref: RHEA:21404
xref: UM-BBD_reactionID:r0982
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.49
+property_value: skos:exactMatch RHEA:21404
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050588
@@ -322714,6 +336229,9 @@
xref: MetaCyc:1.13.12.12-RXN
xref: RHEA:26023
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
+property_value: skos:exactMatch EC:1.13.11.67
+property_value: skos:exactMatch RHEA:26023
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050589
@@ -322728,6 +336246,8 @@
xref: EC:1.14.20.4
xref: MetaCyc:RXN-602
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.20.4
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050590
@@ -322745,6 +336265,9 @@
xref: MetaCyc:1.14.11.20-RXN
xref: RHEA:18973
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.20
+property_value: skos:exactMatch RHEA:18973
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050591
@@ -322759,6 +336282,9 @@
xref: MetaCyc:1.14.13.67-RXN
xref: RHEA:20149
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.55
+property_value: skos:exactMatch RHEA:20149
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050592
@@ -322777,6 +336303,9 @@
xref: MetaCyc:1.14.13.68-RXN
xref: RHEA:18401
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.37
+property_value: skos:exactMatch RHEA:18401
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050593
@@ -322792,6 +336321,9 @@
xref: MetaCyc:1.14.13.71-RXN
xref: RHEA:16649
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.102
+property_value: skos:exactMatch RHEA:16649
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050594
@@ -322804,6 +336336,9 @@
xref: MetaCyc:1.14.13.73-RXN
xref: RHEA:14133
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.103
+property_value: skos:exactMatch RHEA:14133
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050595
@@ -322813,7 +336348,10 @@
xref: MetaCyc:1.14.13.74-RXN
xref: RHEA:11452
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:broadMatch EC:1.14.14.85
+property_value: skos:exactMatch RHEA:11452
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24838" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050596
@@ -322826,6 +336364,9 @@
xref: MetaCyc:1.14.13.75-RXN
xref: RHEA:17257
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.104
+property_value: skos:exactMatch RHEA:17257
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050597
@@ -322841,6 +336382,9 @@
xref: MetaCyc:1.14.13.76-RXN
xref: RHEA:15241
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.105
+property_value: skos:exactMatch RHEA:15241
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050598
@@ -322855,6 +336399,9 @@
xref: MetaCyc:1.14.13.77-RXN
xref: RHEA:18949
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.106
+property_value: skos:exactMatch RHEA:18949
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050599
@@ -322873,6 +336420,9 @@
xref: MetaCyc:1.14.20.1-RXN
xref: RHEA:20748
is_a: GO:0050498 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated
+property_value: skos:exactMatch EC:1.14.20.1
+property_value: skos:exactMatch RHEA:20748
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050600
@@ -322885,8 +336435,11 @@
xref: MetaCyc:1.14.99.31-RXN
xref: RHEA:46396
is_a: GO:0016215 ! acyl-CoA desaturase activity
+property_value: skos:exactMatch EC:1.14.19.24
+property_value: skos:exactMatch RHEA:46396
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22050" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24103" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050602
@@ -322913,6 +336466,9 @@
xref: UM-BBD_reactionID:r1235
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.35
+property_value: skos:exactMatch RHEA:18929
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050604
@@ -322928,6 +336484,9 @@
xref: RHEA:14049
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.14.176
+property_value: skos:exactMatch RHEA:14049
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050605
@@ -322942,6 +336501,9 @@
xref: RHEA:21324
is_a: GO:0016209 ! antioxidant activity
is_a: GO:0016721 ! oxidoreductase activity, acting on superoxide radicals as acceptor
+property_value: skos:exactMatch EC:1.15.1.2
+property_value: skos:exactMatch RHEA:21324
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050606
@@ -322957,6 +336519,9 @@
xref: MetaCyc:1.2.1.45-RXN
xref: RHEA:29587
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.312
+property_value: skos:exactMatch RHEA:29587
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050607
@@ -322969,6 +336534,9 @@
xref: MetaCyc:1.2.1.66-RXN
xref: RHEA:28502
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.306
+property_value: skos:exactMatch RHEA:28502
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050608
@@ -322981,6 +336549,9 @@
xref: MetaCyc:1.2.1.67-RXN
xref: RHEA:13309
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.67
+property_value: skos:exactMatch RHEA:13309
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050609
@@ -322997,6 +336568,9 @@
xref: RHEA:13173
xref: UM-BBD_reactionID:r1055
is_a: GO:0050499 ! oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor
+property_value: skos:exactMatch EC:1.20.1.1
+property_value: skos:exactMatch RHEA:13173
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050610
@@ -323012,6 +336586,9 @@
xref: RHEA:15969
xref: UM-BBD_reactionID:r0837
is_a: GO:0030614 ! oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor
+property_value: skos:exactMatch EC:1.20.4.2
+property_value: skos:exactMatch RHEA:15969
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050611
@@ -323026,6 +336603,9 @@
xref: RHEA:18701
xref: UM-BBD_reactionID:r0634
is_a: GO:0052882 ! oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor
+property_value: skos:exactMatch EC:1.20.9.1
+property_value: skos:exactMatch RHEA:18701
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050612
@@ -323053,9 +336633,11 @@
xref: MetaCyc:RXN66-14
xref: Reactome:R-HSA-194674 "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]"
xref: Reactome:R-HSA-194698 "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2]"
-xref: Reactome:R-HSA-9946140 "TM7SF2 reduces 4,4-diMeCholesta-8,14-dien-3-ol to 4,4-diMe5-cholest-8-en-3-ol"
xref: RHEA:18561
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.70
+property_value: skos:exactMatch RHEA:18561
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050614
@@ -323073,6 +336655,9 @@
xref: Reactome:R-HSA-9755937 "DHCR24 reduces LAN to 24,25-dhLAN"
xref: RHEA:13685
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.72
+property_value: skos:exactMatch RHEA:13685
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050615
@@ -323085,6 +336670,9 @@
xref: MetaCyc:1.3.1.73-RXN
xref: RHEA:12320
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.73
+property_value: skos:exactMatch RHEA:12320
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050616
@@ -323096,6 +336684,9 @@
xref: MetaCyc:1.3.3.9-RXN
xref: RHEA:20585
is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.14.19.62
+property_value: skos:exactMatch RHEA:20585
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050617
@@ -323107,6 +336698,9 @@
xref: MetaCyc:1.3.7.2-RXN
xref: RHEA:10168
is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.3.7.2
+property_value: skos:exactMatch RHEA:10168
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050618
@@ -323119,6 +336713,9 @@
xref: MetaCyc:1.3.7.3-RXN
xref: RHEA:22092
is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.3.7.3
+property_value: skos:exactMatch RHEA:22092
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050619
@@ -323135,6 +336732,9 @@
xref: MetaCyc:1.3.7.4-RXN
xref: RHEA:16377
is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.3.7.4
+property_value: skos:exactMatch RHEA:16377
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050620
@@ -323146,6 +336746,9 @@
xref: MetaCyc:1.3.7.5-RXN
xref: RHEA:15309
is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.3.7.5
+property_value: skos:exactMatch RHEA:15309
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050621
@@ -323162,6 +336765,9 @@
xref: MetaCyc:1.4.3.17-RXN
xref: RHEA:19901
is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.3.3.10
+property_value: skos:exactMatch RHEA:19901
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050622
@@ -323175,6 +336781,9 @@
xref: MetaCyc:1.4.99.5-RXN
xref: RHEA:15821
is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors
+property_value: skos:exactMatch EC:1.4.99.5
+property_value: skos:exactMatch RHEA:15821
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050623
@@ -323188,6 +336797,9 @@
xref: MetaCyc:1.5.1.31-RXN
xref: RHEA:21268
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.31
+property_value: skos:exactMatch RHEA:21268
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050624
@@ -323200,6 +336812,9 @@
xref: MetaCyc:1.5.1.32-RXN
xref: RHEA:16409
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.32
+property_value: skos:exactMatch RHEA:16409
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050625
@@ -323219,6 +336834,8 @@
xref: RHEA:12428
xref: UM-BBD_reactionID:r0667
is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.6.5.7
+property_value: skos:exactMatch RHEA:12428
[Term]
id: GO:0050626
@@ -323233,6 +336850,9 @@
xref: RHEA:24236
xref: Wikipedia:Trimethylamine_N-oxide_reductase
is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.7.2.3
+property_value: skos:exactMatch RHEA:24236
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050627
@@ -323244,6 +336864,8 @@
xref: EC:1.8.1.15
xref: MetaCyc:1.8.1.15-RXN
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:exactMatch EC:1.8.1.15
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050628
@@ -323260,6 +336882,9 @@
xref: RHEA:16977
xref: UM-BBD_reactionID:r0854
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:exactMatch EC:1.8.1.5
+property_value: skos:exactMatch RHEA:16977
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050629
@@ -323272,6 +336897,9 @@
xref: MetaCyc:1.97.1.8-RXN
xref: RHEA:20353
is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond
+property_value: skos:exactMatch EC:1.21.99.5
+property_value: skos:exactMatch RHEA:20353
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050630
@@ -323284,6 +336912,9 @@
xref: MetaCyc:2.1.1.146-RXN
xref: RHEA:17081
is_a: GO:0008171 ! O-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.146
+property_value: skos:exactMatch RHEA:17081
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050631
@@ -323296,6 +336927,9 @@
xref: MetaCyc:2.1.1.147-RXN
xref: RHEA:14773
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.147
+property_value: skos:exactMatch RHEA:14773
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050632
@@ -323322,6 +336956,8 @@
xref: Reactome:R-HSA-390224 "3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA"
xref: RHEA:10408
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:broadMatch EC:2.3.1.176
+property_value: skos:exactMatch RHEA:10408
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -323338,6 +336974,9 @@
xref: RHEA:18161
is_a: GO:0016408 ! C-acyltransferase activity
is_a: GO:0019107 ! myristoyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.155
+property_value: skos:exactMatch RHEA:18161
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050634
@@ -323351,6 +336990,9 @@
xref: MetaCyc:2.3.1.156-RXN
xref: RHEA:23572
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.156
+property_value: skos:exactMatch RHEA:23572
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050635
@@ -323363,6 +337005,9 @@
xref: MetaCyc:2.3.1.159-RXN
xref: RHEA:22224
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.159
+property_value: skos:exactMatch RHEA:22224
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050636
@@ -323375,6 +337020,9 @@
xref: MetaCyc:2.3.1.160-RXN
xref: RHEA:24016
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.160
+property_value: skos:exactMatch RHEA:24016
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050637
@@ -323387,6 +337035,9 @@
xref: MetaCyc:2.3.1.161-RXN
xref: RHEA:18565
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.161
+property_value: skos:exactMatch RHEA:18565
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050638
@@ -323405,6 +337056,9 @@
xref: MetaCyc:2.3.1.162-RXN
xref: RHEA:22028
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.162
+property_value: skos:exactMatch RHEA:22028
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050639
@@ -323419,6 +337073,9 @@
xref: MetaCyc:2.3.1.163-RXN
xref: RHEA:18837
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.163
+property_value: skos:exactMatch RHEA:18837
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050640
@@ -323436,6 +337093,9 @@
xref: MetaCyc:2.3.1.164-RXN
xref: RHEA:20720
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.164
+property_value: skos:exactMatch RHEA:20720
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050641
@@ -323450,6 +337110,9 @@
xref: MetaCyc:2.3.1.165-RXN
xref: RHEA:12240
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.165
+property_value: skos:exactMatch RHEA:12240
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050642
@@ -323467,6 +337130,9 @@
xref: MetaCyc:2.3.1.166-RXN
xref: RHEA:18741
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.166
+property_value: skos:exactMatch RHEA:18741
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050643
@@ -323479,6 +337145,9 @@
xref: MetaCyc:2.3.1.167-RXN
xref: RHEA:20137
is_a: GO:0016413 ! O-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.167
+property_value: skos:exactMatch RHEA:20137
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050644
@@ -323491,6 +337160,9 @@
xref: MetaCyc:2.4.1.209-RXN
xref: RHEA:13129
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.209
+property_value: skos:exactMatch RHEA:13129
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050645
@@ -323504,6 +337176,9 @@
xref: MetaCyc:2.4.1.210-RXN
xref: RHEA:11256
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.210
+property_value: skos:exactMatch RHEA:11256
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050646
@@ -323542,6 +337217,7 @@
synonym: "testosterone 6b-hydroxylase activity" EXACT []
xref: RHEA:46296
is_a: GO:0008395 ! steroid hydroxylase activity
+property_value: skos:exactMatch RHEA:46296
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29080" xsd:anyURI
[Term]
@@ -323685,10 +337361,23 @@
synonym: "GalNAc4S-6ST" RELATED [EC:2.8.2.33]
synonym: "N-acetylgalactosamine 4-sulfate 6-O-sulphotransferase activity" RELATED [EC:2.8.2.33]
xref: EC:2.8.2.33
-xref: Reactome:R-HSA-2018659 "CHST15 transfers sulfate to (6-)GalNAc-4-sulfate"
-xref: Reactome:R-HSA-9941312 "CHST15 transfers sulfate to (6-)GalNAc-4-sulfate"
+xref: KEGG_REACTION:R10868
+xref: KEGG_REACTION:R10869
+xref: MetaCyc:RXN-7953
+xref: MetaCyc:RXN-7954
+xref: Reactome:R-HSA-2018659 "Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15"
+xref: RHEA:54300
+xref: RHEA:54304
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.33
+property_value: skos:narrowMatch KEGG_REACTION:R10868
+property_value: skos:narrowMatch KEGG_REACTION:R10869
+property_value: skos:narrowMatch MetaCyc:RXN-7953
+property_value: skos:narrowMatch MetaCyc:RXN-7954
+property_value: skos:narrowMatch RHEA:54300
+property_value: skos:narrowMatch RHEA:54304
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050660
@@ -323726,6 +337415,8 @@
synonym: "oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor" RELATED []
xref: EC:1.6.3.-
is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H
+property_value: skos:exactMatch EC:1.6.3.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050665
@@ -324096,6 +337787,9 @@
xref: RHEA:23368
xref: UM-BBD_reactionID:r1049
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.7
+property_value: skos:exactMatch RHEA:23368
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050696
@@ -324123,7 +337817,9 @@
xref: UM-BBD_enzymeID:r0350
xref: UM-BBD_enzymeID:r0932
is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond
+property_value: skos:exactMatch RHEA:67992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050698
@@ -324133,6 +337829,7 @@
synonym: "proteoglycan sulfate transfer" RELATED []
synonym: "proteoglycan sulphotransferase activity" EXACT []
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:broadMatch EC:2.8.2.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28380" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
@@ -324459,7 +338156,6 @@
def: "Binding to a low-density lipoprotein receptor." [GOC:ai]
synonym: "LDL receptor binding" EXACT []
synonym: "low-density lipoprotein receptor binding" EXACT [GOC:dph]
-xref: Reactome:R-HSA-2423785 "CR:atREs binds apoE and HSPG"
is_a: GO:0070325 ! lipoprotein particle receptor binding
[Term]
@@ -324530,7 +338226,7 @@
def: "The chemical reactions and pathways involving depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively." [GOC:go_curators]
subset: goslim_pir
synonym: "depsipeptide metabolism" EXACT []
-is_a: GO:0043603 ! amide metabolic process
+is_a: GO:0008152 ! metabolic process
[Term]
id: GO:0050762
@@ -324552,7 +338248,7 @@
synonym: "depsipeptide biosynthesis" EXACT []
synonym: "depsipeptide formation" EXACT []
synonym: "depsipeptide synthesis" EXACT []
-is_a: GO:0043604 ! amide biosynthetic process
+is_a: GO:0009058 ! biosynthetic process
is_a: GO:0050761 ! depsipeptide metabolic process
[Term]
@@ -324810,6 +338506,7 @@
synonym: "galactose, glucose uniporter activity" BROAD []
is_a: GO:0005354 ! galactose transmembrane transporter activity
is_a: GO:0008516 ! hexose uniporter activity
+property_value: skos:broadMatch RHEA:34915
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
[Term]
@@ -324981,6 +338678,9 @@
xref: MetaCyc:RXN-8850
xref: RHEA:29043
is_a: GO:0042083 ! 5,10-methylenetetrahydrofolate-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.148
+property_value: skos:exactMatch RHEA:29043
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0050798
@@ -325169,7 +338869,6 @@
is_a: GO:0009889 ! regulation of biosynthetic process
is_a: GO:0019217 ! regulation of fatty acid metabolic process
is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0042762 ! regulation of sulfur metabolic process
is_a: GO:0051174 ! regulation of phosphorus metabolic process
intersection_of: GO:0065007 ! biological regulation
@@ -327467,6 +341166,8 @@
def: "Catalysis of the joining of a metal ion to a molecule via a nitrogen-metal bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6.6.-.-]
xref: EC:6.6.-.-
is_a: GO:0016874 ! ligase activity
+property_value: skos:exactMatch EC:6.6.-.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051003
@@ -327475,6 +341176,8 @@
def: "Catalysis of the ligation of two substances via a nitrogen-metal bond, forming a coordination complex." [EC:6.6.1.-]
xref: EC:6.6.1.-
is_a: GO:0051002 ! ligase activity, forming nitrogen-metal bonds
+property_value: skos:exactMatch EC:6.6.1.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051004
@@ -327528,6 +341231,9 @@
xref: RHEA:17637
is_a: GO:0016866 ! intramolecular transferase activity
is_a: GO:0034072 ! squalene cyclase activity
+property_value: skos:exactMatch EC:5.4.99.17
+property_value: skos:exactMatch RHEA:17637
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051008
@@ -327546,7 +341252,9 @@
xref: RHEA:27822
is_a: GO:0003961 ! O-acetylhomoserine aminocarboxypropyltransferase activity
is_a: GO:0016835 ! carbon-oxygen lyase activity
+property_value: skos:exactMatch RHEA:27822
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28681" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051010
@@ -328107,6 +341815,8 @@
xref: EC:3.2.1.41
xref: MetaCyc:RXN-1824
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.41
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051061
@@ -328117,6 +341827,8 @@
xref: MetaCyc:ADPREDUCT-RXN
xref: RHEA:28034
is_a: GO:0004748 ! ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
+property_value: skos:exactMatch RHEA:28034
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051062
@@ -328127,6 +341839,8 @@
xref: MetaCyc:UDPREDUCT-RXN
xref: RHEA:28026
is_a: GO:0004748 ! ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
+property_value: skos:exactMatch RHEA:28026
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051063
@@ -328191,7 +341905,6 @@
synonym: "dihydrothioctamide metabolic process" EXACT []
synonym: "dihydrothioctamide metabolism" EXACT []
is_a: GO:0006790 ! sulfur compound metabolic process
-is_a: GO:0043603 ! amide metabolic process
[Term]
id: GO:0051069
@@ -328256,6 +341969,9 @@
xref: MetaCyc:COBALAMINSYN-RXN
xref: RHEA:16049
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.26
+property_value: skos:exactMatch RHEA:16049
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051074
@@ -328278,6 +341994,9 @@
is_a: GO:0016757 ! glycosyltransferase activity
is_a: GO:0016853 ! isomerase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.4.99.17
+property_value: skos:exactMatch RHEA:32155
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051077
@@ -328434,31 +342153,28 @@
[Term]
id: GO:0051090
-name: regulation of DNA-binding transcription factor activity
+name: obsolete regulation of DNA-binding transcription factor activity
namespace: biological_process
alt_id: GO:1904167
alt_id: GO:2000823
-def: "Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:ai]
-subset: gocheck_obsoletion_candidate
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:ai]
+comment: The reason for obsoletion is that this term represents a molecular function.
synonym: "regulation of androgen receptor activity" NARROW []
synonym: "regulation of DNA binding transcription factor activity" EXACT []
synonym: "regulation of sequence-specific DNA binding transcription factor activity" EXACT []
synonym: "regulation of thyroid hormone receptor activity" NARROW []
synonym: "regulation of transcription factor activity" BROAD [GOC:dph, GOC:tb]
xref: Reactome:R-HSA-9708530 "Regulation of BACH1 activity"
-is_a: GO:0006355 ! regulation of DNA-templated transcription
-is_a: GO:0065009 ! regulation of molecular function
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0003700 ! DNA-binding transcription factor activity
-relationship: regulates GO:0003700 ! DNA-binding transcription factor activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30856" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0051091
-name: positive regulation of DNA-binding transcription factor activity
+name: obsolete positive regulation of DNA-binding transcription factor activity
namespace: biological_process
alt_id: GO:1904169
-def: "Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:ai]
-subset: gocheck_obsoletion_candidate
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:ai]
+comment: The reason for obsoletion is that this term represents a molecular function.
synonym: "activation of transcription factor activity" NARROW []
synonym: "positive regulation of DNA binding transcription factor activity" EXACT []
synonym: "positive regulation of sequence-specific DNA binding transcription factor activity" EXACT []
@@ -328468,24 +342184,22 @@
synonym: "up regulation of transcription factor activity" EXACT []
synonym: "up-regulation of transcription factor activity" EXACT []
synonym: "upregulation of transcription factor activity" EXACT []
-is_a: GO:0044093 ! positive regulation of molecular function
-is_a: GO:0051090 ! regulation of DNA-binding transcription factor activity
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0003700 ! DNA-binding transcription factor activity
-relationship: positively_regulates GO:0003700 ! DNA-binding transcription factor activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30856" xsd:anyURI
+is_obsolete: true
created_by: rph
creation_date: 2015-04-22T12:22:16Z
[Term]
id: GO:0051092
-name: positive regulation of NF-kappaB transcription factor activity
+name: obsolete positive regulation of NF-kappaB transcription factor activity
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB." [GOC:dph, GOC:tb, PMID:15087454, PMID:15170030]
-subset: gocheck_obsoletion_candidate
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB." [GOC:dph, GOC:tb, PMID:15087454, PMID:15170030]
+comment: The reason for obsoletion is that this term represents a molecular function.
synonym: "activation of NF-kappaB" EXACT []
synonym: "activation of NF-kappaB transcription factor" EXACT [GOC:dph, GOC:tb]
synonym: "NF-kappaB activation" EXACT []
-is_a: GO:0051091 ! positive regulation of DNA-binding transcription factor activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30856" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0051093
@@ -328693,6 +342407,8 @@
xref: RHEA:30543
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch RHEA:30543
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051109
@@ -328704,6 +342420,8 @@
xref: MetaCyc:CROTCOALIG-RXN
xref: RHEA:30079
is_a: GO:0016405 ! CoA-ligase activity
+property_value: skos:exactMatch RHEA:30079
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051110
@@ -328778,6 +342496,9 @@
xref: MetaCyc:R342-RXN
xref: RHEA:15341
is_a: GO:0051003 ! ligase activity, forming nitrogen-metal bonds, forming coordination complexes
+property_value: skos:exactMatch EC:6.6.1.2
+property_value: skos:exactMatch RHEA:15341
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051117
@@ -328801,7 +342522,9 @@
xref: EC:3.2.1.59
xref: MetaCyc:3.2.1.59-RXN
is_a: GO:0090599 ! alpha-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.59
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28262" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051119
@@ -328820,6 +342543,8 @@
namespace: molecular_function
def: "OBSOLETE. Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3." [PMID:15123652]
comment: The reason for obsoletion is that this term is equivalent to hydroperoxy icosatetraenoate isomerase activity.
+xref: Reactome:R-HSA-2161794 "Arachidonate is converted to HXA3/B3 by ALOX12"
+xref: Reactome:R-HSA-8942208 "ALOXE3 isomerises 12R-HpETE to HXA3"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29695" xsd:anyURI
is_obsolete: true
replaced_by: GO:0106255
@@ -329925,8 +343650,10 @@
synonym: "protein insertion into mitochondrion membrane" EXACT []
synonym: "protein-mitochondrial membrane insertion" EXACT []
synonym: "protein-mitochondrion membrane insertion" EXACT []
+is_a: GO:0007006 ! mitochondrial membrane organization
is_a: GO:0051205 ! protein insertion into membrane
-is_a: GO:0090151 ! establishment of protein localization to mitochondrial membrane
+is_a: GO:0051649 ! establishment of localization in cell
+is_a: GO:0072594 ! establishment of protein localization to organelle
relationship: part_of GO:0070585 ! protein localization to mitochondrion
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/15800" xsd:anyURI
@@ -330696,6 +344423,9 @@
xref: MetaCyc:SIROHEME-FERROCHELAT-RXN
xref: RHEA:24360
is_a: GO:0004325 ! ferrochelatase activity
+property_value: skos:exactMatch EC:4.99.1.4
+property_value: skos:exactMatch RHEA:24360
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051267
@@ -330723,6 +344453,7 @@
def: "Catalysis of the reaction: alpha-ketoester + H+ + NADPH = (R)-hydroxy ester + NADP+." [PMID:15564669, RHEA:80767]
xref: RHEA:80767
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:80767
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28345" xsd:anyURI
[Term]
@@ -332206,10 +345937,12 @@
xref: RHEA:53876
is_a: GO:0008080 ! N-acetyltransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch RHEA:53876
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26617" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29506" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30121" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30124" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051393
@@ -333409,20 +347142,19 @@
[Term]
id: GO:0051484
-name: isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
+name: obsolete isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway that contributes to terpenoid biosynthesis. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate." [GOC:ai]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway that contributes to terpenoid biosynthesis. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate." [GOC:ai]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM.
synonym: "isopentenyl diphosphate anabolism, mevalonate-independent pathway, during terpenoid anabolism" RELATED []
synonym: "isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway involved in terpenoid biosynthetic process" RELATED []
synonym: "isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway, during terpenoid biosynthetic process" RELATED [GOC:dph, GOC:tb]
synonym: "isopentenyl diphosphate formation, mevalonate-independent pathway, during terpenoid biosynthesis" RELATED []
synonym: "isopentenyl diphosphate formation, mevalonate-independent pathway, during terpenoid formation" RELATED []
synonym: "isopentenyl diphosphate synthesis, mevalonate-independent pathway, during terpenoid synthesis" RELATED []
-is_a: GO:0019288 ! isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
-intersection_of: GO:0019288 ! isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
-intersection_of: part_of GO:0016114 ! terpenoid biosynthetic process
-relationship: part_of GO:0051483 ! terpenoid biosynthetic process, mevalonate-independent
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31228" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0051485
@@ -333438,18 +347170,17 @@
[Term]
id: GO:0051486
-name: isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process
+name: obsolete isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates." [GOC:ai]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates." [GOC:ai]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM.
synonym: "isopentenyl diphosphate anabolism, mevalonate pathway, during terpenoid anabolism" RELATED []
synonym: "isopentenyl diphosphate biosynthetic process, mevalonate pathway, during terpenoid biosynthetic process" RELATED [GOC:dph, GOC:tb]
synonym: "isopentenyl diphosphate formation, mevalonate pathway, during terpenoid biosynthesis" RELATED []
synonym: "isopentenyl diphosphate formation, mevalonate pathway, during terpenoid formation" RELATED []
synonym: "isopentenyl diphosphate synthesis, mevalonate pathway, during terpenoid synthesis" RELATED []
-is_a: GO:0019287 ! isopentenyl diphosphate biosynthetic process, mevalonate pathway
-intersection_of: GO:0019287 ! isopentenyl diphosphate biosynthetic process, mevalonate pathway
-intersection_of: part_of GO:0016114 ! terpenoid biosynthetic process
-relationship: part_of GO:0051485 ! terpenoid biosynthetic process, mevalonate-dependent
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31228" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0051489
@@ -333606,6 +347337,9 @@
xref: MetaCyc:RXN-8528
xref: RHEA:25524
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.14
+property_value: skos:exactMatch RHEA:25524
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051499
@@ -333616,7 +347350,10 @@
xref: MetaCyc:RXN-15041
xref: RHEA:13953
is_a: GO:0002161 ! aminoacyl-tRNA deacylase activity
+property_value: skos:exactMatch EC:3.1.1.96
+property_value: skos:exactMatch RHEA:13953
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29746" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051500
@@ -333625,6 +347362,8 @@
def: "Catalysis of the reaction: D-tyrosyl-tRNATyr + H2O = D-tyrosine + tRNATyr. Removal of a D-tyrosine from a charged tRNA(Tyr)." [PMID:14527667, RHEA:25347]
xref: RHEA:25347
is_a: GO:0051499 ! D-aminoacyl-tRNA deacylase activity
+property_value: skos:broadMatch EC:3.1.1.96
+property_value: skos:exactMatch RHEA:25347
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -334381,6 +348120,7 @@
xref: RHEA:76255
is_a: GO:0016835 ! carbon-oxygen lyase activity
is_a: GO:0140097 ! catalytic activity, acting on DNA
+property_value: skos:exactMatch RHEA:76255
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29090" xsd:anyURI
[Term]
@@ -334591,11 +348331,30 @@
synonym: "methylglyoxal breakdown" EXACT []
synonym: "methylglyoxal catabolism" EXACT []
synonym: "methylglyoxal degradation" EXACT []
+xref: MetaCyc:METHGLYUT-PWY
xref: MetaCyc:Methylglyoxal-Detoxification
+xref: MetaCyc:PWY-5386-1
+xref: MetaCyc:PWY-5453
+xref: MetaCyc:PWY-5456
+xref: MetaCyc:PWY-5458
+xref: MetaCyc:PWY-5459
+xref: MetaCyc:PWY-5462
+xref: MetaCyc:PWY-8458
+xref: MetaCyc:PWY8J2-23
is_a: GO:0009438 ! methylglyoxal metabolic process
is_a: GO:0042182 ! ketone catabolic process
is_a: GO:0046185 ! aldehyde catabolic process
is_a: GO:0140041 ! cellular detoxification of methylglyoxal
+property_value: skos:exactMatch MetaCyc:Methylglyoxal-Detoxification
+property_value: skos:narrowMatch MetaCyc:METHGLYUT-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-5386-1
+property_value: skos:narrowMatch MetaCyc:PWY-5453
+property_value: skos:narrowMatch MetaCyc:PWY-5456
+property_value: skos:narrowMatch MetaCyc:PWY-5458
+property_value: skos:narrowMatch MetaCyc:PWY-5459
+property_value: skos:narrowMatch MetaCyc:PWY-5462
+property_value: skos:narrowMatch MetaCyc:PWY-8458
+property_value: skos:narrowMatch MetaCyc:PWY8J2-23
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30239" xsd:anyURI
@@ -334664,10 +348423,10 @@
[Term]
id: GO:0051603
-name: proteolysis involved in protein catabolic process
+name: obsolete proteolysis involved in protein catabolic process
namespace: biological_process
-def: "The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells." [GOC:ai, GOC:dph, GOC:tb]
-subset: goslim_yeast
+def: "OBSOLETE. The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells." [GOC:ai, GOC:dph, GOC:tb]
+comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
synonym: "peptidolysis during cellular protein catabolic process" RELATED []
synonym: "peptidolysis during cellular protein catabolism" RELATED []
synonym: "peptidolysis involved in cellular protein catabolic process" EXACT []
@@ -334675,11 +348434,10 @@
synonym: "proteolysis during cellular protein catabolic process" RELATED []
synonym: "proteolysis during cellular protein catabolism" RELATED []
synonym: "proteolysis involved in cellular protein catabolic process" EXACT []
-is_a: GO:0006508 ! proteolysis
-intersection_of: GO:0006508 ! proteolysis
-intersection_of: part_of GO:0030163 ! protein catabolic process
-relationship: part_of GO:0030163 ! protein catabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31208" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0030163
[Term]
id: GO:0051604
@@ -335487,6 +349245,8 @@
xref: EC:3.2.1.80
xref: MetaCyc:3.2.1.80-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.80
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051670
@@ -335501,6 +349261,8 @@
xref: EC:3.2.1.7
xref: MetaCyc:3.2.1.7-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.7
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051671
@@ -335569,6 +349331,8 @@
xref: EC:3.2.1.57
xref: MetaCyc:3.2.1.57-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.57
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051676
@@ -335778,6 +349542,8 @@
xref: EC:1.5.3.18
xref: RHEA:28210
is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.5.3.18
+property_value: skos:exactMatch RHEA:28210
[Term]
id: GO:0051699
@@ -336032,6 +349798,8 @@
xref: Reactome:R-HSA-1855205 "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol"
xref: RHEA:77155
is_a: GO:0052743 ! inositol tetrakisphosphate phosphatase activity
+property_value: skos:exactMatch MetaCyc:3.1.3.62-RXN
+property_value: skos:exactMatch RHEA:77155
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -336056,6 +349824,7 @@
xref: Reactome:R-HSA-5334152 "DNMT3A:DNMT3L methylates cytosine in DNA"
xref: Reactome:R-HSA-9845308 "DNMT3A:DNMT3L in nascent RNA transcript:MeR-PIWIL4:2'-O-methyl-piRNA:SPOCD1:DNMT3A:DNMT3L methylates cytosine in DNA"
is_a: GO:0003886 ! DNA (cytosine-5-)-methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.37
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28396" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -336065,6 +349834,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG." [PMID:15689527]
is_a: GO:0003886 ! DNA (cytosine-5-)-methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.37
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28396" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -336083,6 +349853,7 @@
def: "OBSOLETE. Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol." [PMID:10318862, PMID:8650216]
comment: This seems to be outside the scope of GO: it represent a specific protein and a 'domain.
synonym: "protein phosphatase methylesterase activity" NARROW []
+xref: Reactome:R-HSA-8856951 "PP2A demethylation by PPME1"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27558" xsd:anyURI
is_obsolete: true
replaced_by: GO:0051723
@@ -336096,10 +349867,15 @@
synonym: "protein carboxyl methylesterase activity" RELATED [EC:2.7.1.-]
synonym: "protein carboxylic ester hydrolase activity" EXACT []
synonym: "protein methyl-esterase activity" RELATED [EC:2.7.1.-]
+xref: EC:3.1.1.89
+xref: MetaCyc:RXN-12322
xref: Reactome:R-HSA-5367022 "DPH7 hydrolyzes a methyl group on Me-diphthine EEF2"
-xref: Reactome:R-HSA-8856951 "PP2A demethylation by PPME1"
+xref: RHEA:48548
is_a: GO:0052689 ! carboxylic ester hydrolase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:narrowMatch EC:3.1.1.89
+property_value: skos:narrowMatch MetaCyc:RXN-12322
+property_value: skos:narrowMatch RHEA:48548
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27558" xsd:anyURI
[Term]
@@ -336119,7 +349895,6 @@
synonym: "oxidized nicotinamide adenine dinucleotide transmembrane transporter activity" EXACT []
synonym: "reduced NAD transporter activity" EXACT []
synonym: "reduced nicotinamide adenine dinucleotide transmembrane transporter activity" EXACT []
-xref: Reactome:R-HSA-9938195 "SLC25A51 mediates mitochondrial uptake of NAD+"
is_a: GO:0000295 ! adenine nucleotide transmembrane transporter activity
relationship: part_of GO:0035352 ! NAD transmembrane transport
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21577" xsd:anyURI
@@ -336283,8 +350058,10 @@
synonym: "polynucleotide kinase activity" BROAD []
xref: EC:2.7.1.78
is_a: GO:0051731 ! polynucleotide 5'-hydroxyl-kinase activity
+property_value: skos:exactMatch EC:2.7.1.78
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21619" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25049" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051735
@@ -336305,7 +350082,9 @@
synonym: "polyribonucleotide 5'-hydroxyl-kinase activity" BROAD []
xref: RHEA:54580
is_a: GO:0051734 ! ATP-dependent polynucleotide 5'-hydroxyl-kinase activity
+property_value: skos:exactMatch RHEA:54580
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25049" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051737
@@ -336342,6 +350121,8 @@
xref: MetaCyc:RXN-2542
xref: RHEA:37979
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch RHEA:37979
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051742
@@ -336352,16 +350133,23 @@
xref: MetaCyc:RXN-2762
xref: RHEA:37999
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch RHEA:37999
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051743
name: red chlorophyll catabolite reductase activity
namespace: molecular_function
-def: "Catalysis of the reaction: red chlorophyll catabolite + reduced ferredoxin + 2 H+ = primary fluorescent catabolite + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence." [PMID:10743659]
+def: "Catalysis of the reaction: primary fluorescent chlorophyll catabolite + 2 oxidized [2Fe-2S]-[ferredoxin] = red chlorophyll catabolite + 2 reduced [2Fe-2S]-[ferredoxin] + 3 H+. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence." [PMID:10743659, RHEA:24752]
synonym: "RCC reductase activity" EXACT []
+xref: EC:1.3.7.12
xref: MetaCyc:RXN-7741
xref: RHEA:24752
is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.3.7.12
+property_value: skos:exactMatch MetaCyc:RXN-7741
+property_value: skos:exactMatch RHEA:24752
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0051744
@@ -336383,8 +350171,14 @@
xref: EC:1.17.7.4
xref: KEGG_REACTION:R05884
xref: MetaCyc:ISPH2-RXN
+xref: RHEA:24488
+xref: RHEA:24825
is_a: GO:0052592 ! oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.17.7.4
+property_value: skos:narrowMatch RHEA:24488
+property_value: skos:narrowMatch RHEA:24825
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27696" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051746
@@ -336394,6 +350188,9 @@
xref: EC:5.4.99.31
xref: RHEA:26160
is_a: GO:0031559 ! oxidosqualene cyclase activity
+property_value: skos:exactMatch EC:5.4.99.31
+property_value: skos:exactMatch RHEA:26160
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051747
@@ -336420,6 +350217,9 @@
xref: MetaCyc:2.7.7.64-RXN
xref: RHEA:13205
is_a: GO:0070569 ! uridylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.64
+property_value: skos:exactMatch RHEA:13205
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051749
@@ -336441,6 +350241,9 @@
xref: EC:5.3.3.21
xref: RHEA:45240
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.21
+property_value: skos:exactMatch RHEA:45240
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051751
@@ -336462,6 +350265,8 @@
xref: RHEA:10256
is_a: GO:0016301 ! kinase activity
is_a: GO:0016781 ! phosphotransferase activity, paired acceptors
+property_value: skos:exactMatch EC:2.7.9.5
+property_value: skos:exactMatch RHEA:10256
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -336736,7 +350541,10 @@
xref: EC:1.14.14.107
xref: RHEA:33219
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.107
+property_value: skos:exactMatch RHEA:33219
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051778
@@ -336857,6 +350665,9 @@
xref: RHEA:19193
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
relationship: part_of GO:0042572 ! retinol metabolic process
+property_value: skos:exactMatch EC:1.3.99.23
+property_value: skos:exactMatch RHEA:19193
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051787
@@ -337243,10 +351054,14 @@
[Term]
id: GO:0051838
-name: cytolysis by host of symbiont cells
+name: obsolete cytolysis by host of symbiont cells
namespace: biological_process
-def: "The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:add]
-is_a: GO:0051873 ! killing by host of symbiont cells
+def: "OBSOLETE. The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:add]
+comment: This term was obsoleted because it is redundant with other more specific processes, such as\ninnate immune response ; GO:0045087, and natural killer cell mediated cytotoxicity ; GO:0042267.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31230" xsd:anyURI
+is_obsolete: true
+consider: GO:0042267
+consider: GO:0045087
[Term]
id: GO:0051839
@@ -337256,7 +351071,6 @@
comment: This term was obsoleted because it has been used inconsistently.
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/13041" xsd:anyURI
is_obsolete: true
-consider: GO:0051873
[Term]
id: GO:0051840
@@ -337284,7 +351098,6 @@
synonym: "upregulation by host of cytolysis of symbiont cells" EXACT []
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/13041" xsd:anyURI
is_obsolete: true
-consider: GO:0051873
[Term]
id: GO:0051842
@@ -337531,7 +351344,6 @@
namespace: molecular_function
def: "Binding to methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA." [GOC:nln]
is_a: GO:0031406 ! carboxylic acid binding
-is_a: GO:0033218 ! amide binding
is_a: GO:1901363 ! heterocyclic compound binding
[Term]
@@ -337560,15 +351372,16 @@
[Term]
id: GO:0051873
-name: killing by host of symbiont cells
+name: obsolete killing by host of symbiont cells
namespace: biological_process
-alt_id: GO:0051852
-def: "Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:add]
+def: "OBSOLETE. Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:add]
+comment: This term was obsoleted because it is redundant with other more specific processes, such as\ninnate immune response ; GO:0045087, and natural killer cell mediated cytotoxicity ; GO:0042267.
synonym: "disruption by host of symbiont cells" BROAD []
-is_a: GO:0031640 ! killing of cells of another organism
-is_a: GO:0051702 ! biological process involved in interaction with symbiont
-is_a: GO:0140546 ! defense response to symbiont
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18719" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31230" xsd:anyURI
+is_obsolete: true
+consider: GO:0042267
+consider: GO:0045087
[Term]
id: GO:0051874
@@ -338004,7 +351817,9 @@
xref: Reactome:R-HSA-5692237 "ADH5 oxidises S-HMGSH to S-FGSH"
xref: UM-BBD_reactionID:r1146
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.284
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27135" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051904
@@ -338049,6 +351864,9 @@
xref: RHEA:22488
xref: UM-BBD_reactionID:r1145
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch EC:4.4.1.22
+property_value: skos:exactMatch RHEA:22488
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051908
@@ -338060,7 +351878,9 @@
xref: EC:3.1.11.3
is_a: GO:0008309 ! double-stranded DNA exodeoxyribonuclease activity
is_a: GO:0035312 ! 5'-3' DNA exonuclease activity
+property_value: skos:exactMatch EC:3.1.11.3
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26645" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051909
@@ -338089,6 +351909,9 @@
xref: MetaCyc:RXN-7733
xref: RHEA:24436
is_a: GO:0046995 ! oxidoreductase activity, acting on hydrogen as donor, with other known acceptors
+property_value: skos:exactMatch EC:1.12.98.3
+property_value: skos:exactMatch RHEA:24436
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051912
@@ -338105,6 +351928,9 @@
xref: MetaCyc:1.8.98.1-RXN
xref: RHEA:18085
is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors
+property_value: skos:exactMatch EC:1.8.98.1
+property_value: skos:exactMatch RHEA:18085
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051913
@@ -338197,7 +352023,7 @@
name: peroxiredoxin activity
namespace: molecular_function
def: "Catalysis of the reaction: [protein]-dithol + ROOH = [protein]-disulfide + H2O + ROH." [RHEA:10008]
-comment: Includes redox chemistry as part of the catalytic reaction (2 R'-SH = R'-S-S-R'), where R' refers to peroxiredoxin itself). Not to be confused with GO:0004601 (peroxidase activity, EC:1.11.1.7), which has a different reaction mechanism.
+comment: Includes redox chemistry as part of the catalytic reaction (2 R'-SH = R'-S-S-R'), where R' refers to peroxiredoxin itself).
synonym: "PRDX activity" EXACT []
synonym: "Prx activity" EXACT []
xref: Reactome:R-HSA-1222431 "Peroxynitrite is reduced to nitrite by AhpC"
@@ -338205,8 +352031,11 @@
xref: Reactome:R-HSA-1500804 "Peroxynitrite is reduced by AhpE"
xref: RHEA:10008
is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch RHEA:10008
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22598" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23121" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31239" xsd:anyURI
[Term]
id: GO:0051921
@@ -338224,6 +352053,9 @@
xref: MetaCyc:R345-RXN
xref: RHEA:23256
is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor
+property_value: skos:exactMatch EC:6.3.5.10
+property_value: skos:exactMatch RHEA:23256
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051922
@@ -338232,7 +352064,9 @@
def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + cholesterol = adenosine 3',5'-bisphosphate + cholesterol sulfate + H+." [PMID:11416019, PMID:12145317, PMID:12730293, RHEA:52368]
xref: RHEA:52368
is_a: GO:0004027 ! alcohol sulfotransferase activity
+property_value: skos:exactMatch RHEA:52368
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23438" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051923
@@ -338575,9 +352409,10 @@
[Term]
id: GO:0051947
-name: regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse
+name: obsolete regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell." [GOC:ai]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell." [GOC:ai]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "regulation of 4-aminobutyrate reuptake" EXACT []
synonym: "regulation of 4-aminobutyrate uptake during transmission of nerve impulse" EXACT []
synonym: "regulation of GABA reuptake" EXACT []
@@ -338585,17 +352420,16 @@
synonym: "regulation of gamma-aminobutyric acid reuptake" EXACT []
synonym: "regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb]
synonym: "regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse" EXACT [GOC:dph]
-is_a: GO:0032890 ! regulation of organic acid transport
-is_a: GO:0051941 ! regulation of amino acid uptake involved in synaptic transmission
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0051936 ! gamma-aminobutyric acid reuptake
-relationship: regulates GO:0051936 ! gamma-aminobutyric acid reuptake
+is_obsolete: true
+consider: GO:0019226
+consider: GO:0051936
[Term]
id: GO:0051948
-name: negative regulation of glutamate uptake involved in transmission of nerve impulse
+name: obsolete negative regulation of glutamate uptake involved in transmission of nerve impulse
namespace: biological_process
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell." [GOC:ai]
+def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell." [GOC:ai]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of glutamate uptake during transmission of nerve impulse" EXACT []
synonym: "down-regulation of glutamate uptake during transmission of nerve impulse" EXACT []
synonym: "downregulation of glutamate uptake during transmission of nerve impulse" EXACT []
@@ -338603,18 +352437,17 @@
synonym: "negative regulation of glutamate reuptake" EXACT []
synonym: "negative regulation of glutamate uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb]
synonym: "negative regulation of glutamate uptake involved in conduction of nerve impulse" RELATED [GOC:dph]
-is_a: GO:0002037 ! negative regulation of L-glutamate import across plasma membrane
-is_a: GO:0051942 ! negative regulation of amino acid uptake involved in synaptic transmission
-is_a: GO:0051946 ! regulation of glutamate uptake involved in transmission of nerve impulse
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0051935 ! glutamate reuptake
-relationship: negatively_regulates GO:0051935 ! glutamate reuptake
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0002037
+consider: GO:0019226
[Term]
id: GO:0051949
-name: negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse
+name: obsolete negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse
namespace: biological_process
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell." [GOC:ai]
+def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell." [GOC:ai]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" EXACT []
synonym: "down-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" EXACT []
synonym: "downregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" EXACT []
@@ -338626,18 +352459,17 @@
synonym: "negative regulation of gamma-aminobutyric acid reuptake" EXACT []
synonym: "negative regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb]
synonym: "negative regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse" EXACT [GOC:dph]
-is_a: GO:0032891 ! negative regulation of organic acid transport
-is_a: GO:0051942 ! negative regulation of amino acid uptake involved in synaptic transmission
-is_a: GO:0051947 ! regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0051936 ! gamma-aminobutyric acid reuptake
-relationship: negatively_regulates GO:0051936 ! gamma-aminobutyric acid reuptake
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0019226
+consider: GO:0051936
[Term]
id: GO:0051950
-name: positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse
+name: obsolete positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse
namespace: biological_process
-def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell." [GOC:ai]
+def: "OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell." [GOC:ai]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of gamma-aminobutyric acid uptake during transmission of nerve impulse" NARROW []
synonym: "positive regulation of 4-aminobutyrate reuptake" EXACT []
synonym: "positive regulation of 4-aminobutyrate uptake during transmission of nerve impulse" EXACT []
@@ -338650,12 +352482,10 @@
synonym: "up regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" EXACT []
synonym: "up-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" EXACT []
synonym: "upregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" EXACT []
-is_a: GO:0032892 ! positive regulation of organic acid transport
-is_a: GO:0051943 ! positive regulation of amino acid uptake involved in synaptic transmission
-is_a: GO:0051947 ! regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0051936 ! gamma-aminobutyric acid reuptake
-relationship: positively_regulates GO:0051936 ! gamma-aminobutyric acid reuptake
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0019226
+consider: GO:0051936
[Term]
id: GO:0051951
@@ -338767,7 +352597,7 @@
namespace: biological_process
def: "The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase." [GOC:ai]
is_a: GO:0006835 ! dicarboxylic acid transport
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
[Term]
id: GO:0051959
@@ -339000,23 +352830,25 @@
[Term]
id: GO:0051975
-name: lysine biosynthetic process via alpha-aminoadipate and saccharopine
+name: L-lysine biosynthetic process via alpha-aminoadipate and saccharopine
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine." [MetaCyc:LYSINE-AMINOAD-PWY]
+def: "The chemical reactions and pathways resulting in the formation of L-lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine." [MetaCyc:LYSINE-AMINOAD-PWY]
synonym: "lysine biosynthesis via aminoadipic acid and saccharopine" EXACT []
synonym: "lysine biosynthetic process via aminoadipic acid and saccharopine" EXACT []
xref: MetaCyc:LYSINE-AMINOAD-PWY
-is_a: GO:0019878 ! lysine biosynthetic process via aminoadipic acid
+is_a: GO:0019878 ! L-lysine biosynthetic process via aminoadipic acid
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30820" xsd:anyURI
[Term]
id: GO:0051976
-name: lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate
+name: L-lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine." [MetaCyc:PWY-3081]
+def: "The chemical reactions and pathways resulting in the formation of L-lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine." [MetaCyc:PWY-3081]
synonym: "lysine biosynthesis via aminoadipic acid and N2-acetyl-alpha-aminoadipate" EXACT []
synonym: "lysine biosynthetic process via aminoadipic acid and N2-acetyl-alpha-aminoadipate" EXACT []
xref: MetaCyc:PWY-3081
-is_a: GO:0019878 ! lysine biosynthetic process via aminoadipic acid
+is_a: GO:0019878 ! L-lysine biosynthetic process via aminoadipic acid
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30820" xsd:anyURI
[Term]
id: GO:0051977
@@ -339168,6 +353000,9 @@
xref: MetaCyc:HEMN-RXN
xref: RHEA:15425
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.98.3
+property_value: skos:exactMatch RHEA:15425
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0051990
@@ -339181,6 +353016,9 @@
xref: Reactome:R-HSA-880053 "2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1]"
xref: RHEA:38295
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.99.39
+property_value: skos:exactMatch MetaCyc:RXN-14932
+property_value: skos:exactMatch RHEA:38295
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -339191,6 +353029,8 @@
xref: MetaCyc:NACGLCTRANS-RXN
xref: RHEA:31227
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
+property_value: skos:broadMatch EC:2.4.1.227
+property_value: skos:exactMatch RHEA:31227
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
created_by: ai
creation_date: 2010-07-06T11:53:19Z
@@ -339205,6 +353045,8 @@
xref: MetaCyc:PHOSNACMURPENTATRANS-RXN
xref: RHEA:28386
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:broadMatch EC:2.7.8.13
+property_value: skos:exactMatch RHEA:28386
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
created_by: ai
creation_date: 2010-07-06T12:10:01Z
@@ -339219,6 +353061,9 @@
xref: MetaCyc:RXN-11469
xref: RHEA:31347
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.175
+property_value: skos:exactMatch RHEA:31347
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2010-07-16T02:16:59Z
@@ -339254,9 +353099,12 @@
synonym: "squalene synthetase activity" RELATED [EC:2.5.1.21]
xref: EC:2.5.1.21
xref: MetaCyc:RXN66-281
-xref: Reactome:R-HSA-191402 "Reduction of presqualene diphosphate to form squalene"
-xref: Reactome:R-HSA-191405 "Two FPP molecules dimerize to form presqualene diphosphate"
+xref: RHEA:32295
+xref: RHEA:32299
is_a: GO:0004659 ! prenyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.21
+property_value: skos:narrowMatch RHEA:32295
+property_value: skos:narrowMatch RHEA:32299
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28819" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
@@ -339275,7 +353123,10 @@
xref: MetaCyc:RXN-6201
xref: RHEA:26301
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.97
+property_value: skos:exactMatch RHEA:26301
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25283" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2010-07-19T10:47:15Z
@@ -339294,7 +353145,7 @@
id: GO:0051999
name: mannosyl-inositol phosphorylceramide biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative." [GOC:ai]
+def: "The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative." [PMID:20388730]
synonym: "mannose inositol phosphoceramide biosynthetic process" EXACT []
synonym: "mannose-inositol-P-ceramide (MIPC) biosynthetic process" EXACT []
synonym: "mannosyl-inositol phosphorylceramide anabolism" EXACT []
@@ -340986,9 +354837,11 @@
synonym: "up-regulation by symbiont of host apoptosis" EXACT []
synonym: "upregulation by organism of host apoptotic programmed cell death" EXACT []
synonym: "upregulation by symbiont of host apoptosis" EXACT []
+xref: VZ:910 "Activation of host caspases by virus"
is_a: GO:0001907 ! symbiont-mediated killing of host cell
is_a: GO:0052042 ! symbiont-mediated activation of host programmed cell death
is_a: GO:0052150 ! symbiont-mediated perturbation of host apoptosis
+property_value: skos:narrowMatch VZ:910
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25986" xsd:anyURI
[Term]
@@ -342357,7 +356210,6 @@
synonym: "modification by host of symbiont membrane" RELATED []
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24085" xsd:anyURI
is_obsolete: true
-consider: GO:0051873
consider: GO:0061844
[Term]
@@ -342372,7 +356224,6 @@
synonym: "disruption by host of symbiont cell wall" RELATED []
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24085" xsd:anyURI
is_obsolete: true
-consider: GO:0051873
consider: GO:0061844
[Term]
@@ -342740,6 +356591,9 @@
xref: RHEA:26482
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.5.1.75
+property_value: skos:exactMatch RHEA:26482
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30728" xsd:anyURI
creation_date: 2010-07-23T03:07:33Z
@@ -344395,7 +358249,11 @@
xref: MetaCyc:RXN-8562
xref: RHEA:12016
is_a: GO:0010334 ! sesquiterpene synthase activity
+property_value: skos:broadMatch EC:4.2.3.22
+property_value: skos:exactMatch EC:4.2.3.75
+property_value: skos:exactMatch RHEA:12016
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28268" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2010-08-09T01:39:02Z
@@ -344403,11 +358261,16 @@
id: GO:0052578
name: alpha-farnesene synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,E)-alpha-farnesene + diphosphate." [MetaCyc:RXN-8574]
+def: "Catalysis of the reaction: (2E,6E)-farnesyl diphosphate = (3E,6E)-alpha-farnesene + diphosphate." [RHEA:27421]
synonym: "(E,E)-alpha-farnesene synthase activity" EXACT [MetaCyc:RXN-8574]
+xref: EC:4.2.3.46
xref: MetaCyc:RXN-8574
xref: RHEA:27421
is_a: GO:0010334 ! sesquiterpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.46
+property_value: skos:exactMatch MetaCyc:RXN-8574
+property_value: skos:exactMatch RHEA:27421
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: ai
creation_date: 2010-08-09T01:39:42Z
@@ -344418,7 +358281,16 @@
def: "Catalysis of the reaction: (1R,4S)-menthone + NADP+ = (R)-pulegone + H+ + NADPH. Also converts (2R,5R)-isomenthone into (R)-pulegone." [EC:1.3.1.81]
synonym: "(+)-isomenthone:NADP+ oxidoreductase activity" RELATED [EC:1.3.1.81]
xref: EC:1.3.1.81
+xref: MetaCyc:RXN-5163
+xref: MetaCyc:RXN-5164
+xref: RHEA:25641
+xref: RHEA:25645
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.81
+property_value: skos:narrowMatch MetaCyc:RXN-5163
+property_value: skos:narrowMatch MetaCyc:RXN-5164
+property_value: skos:narrowMatch RHEA:25641
+property_value: skos:narrowMatch RHEA:25645
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28161" xsd:anyURI
created_by: ai
creation_date: 2010-08-09T04:28:00Z
@@ -344446,6 +358318,9 @@
xref: MetaCyc:RXN-5161
xref: RHEA:25649
is_a: GO:0035671 ! enone reductase activity
+property_value: skos:exactMatch EC:1.3.1.82
+property_value: skos:exactMatch RHEA:25649
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2010-08-09T04:42:05Z
@@ -344464,6 +358339,9 @@
xref: MetaCyc:1.14.13.104-RXN
xref: RHEA:25658
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.143
+property_value: skos:exactMatch RHEA:25658
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2010-08-09T04:47:42Z
@@ -344520,6 +358398,9 @@
xref: MetaCyc:RXN-11036
xref: RHEA:22900
is_a: GO:0019152 ! acetoin dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.303
+property_value: skos:exactMatch RHEA:22900
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052588
@@ -344532,6 +358413,9 @@
xref: MetaCyc:RXN-11032
xref: RHEA:27286
is_a: GO:0019152 ! acetoin dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.304
+property_value: skos:exactMatch RHEA:27286
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052589
@@ -344571,6 +358455,8 @@
synonym: "oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulphur protein as acceptor" EXACT []
xref: EC:1.17.7.-
is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups
+property_value: skos:exactMatch EC:1.17.7.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052593
@@ -344604,6 +358490,8 @@
xref: MetaCyc:AMINEOXID-RXN
is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
is_a: GO:0030058 ! aliphatic amine dehydrogenase activity
+property_value: skos:broadMatch EC:1.4.3.21
+property_value: skos:broadMatch RHEA:16153
[Term]
id: GO:0052596
@@ -344621,8 +358509,20 @@
namespace: molecular_function
def: "Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH4+ + H2O2." [MetaCyc:RXN-9599]
synonym: "diamine:oxygen oxidoreductase (deaminating) activity" EXACT systematic_synonym [EC:1.4.3.22]
+xref: KEGG_REACTION:R03139
+xref: KEGG_REACTION:R05334
+xref: MetaCyc:RXN-6381
+xref: MetaCyc:RXN-8244
xref: MetaCyc:RXN-9599
+xref: RHEA:30895
is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
+property_value: skos:broadMatch EC:1.4.3.22
+property_value: skos:exactMatch MetaCyc:RXN-9599
+property_value: skos:narrowMatch KEGG_REACTION:R03139
+property_value: skos:narrowMatch KEGG_REACTION:R05334
+property_value: skos:narrowMatch MetaCyc:RXN-6381
+property_value: skos:narrowMatch MetaCyc:RXN-8244
+property_value: skos:narrowMatch RHEA:30895
[Term]
id: GO:0052598
@@ -344637,7 +358537,10 @@
xref: Reactome:R-HSA-5696131 "AOC1 deaminates Hist"
xref: RHEA:25625
is_a: GO:0052597 ! diamine oxidase activity
+property_value: skos:broadMatch EC:1.4.3.22
+property_value: skos:exactMatch RHEA:25625
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052599
@@ -344671,8 +358574,33 @@
synonym: "(S)-limonene,NAD(P)H:oxygen oxidoreductase activity" EXACT systematic_synonym [EC:1.14.13.107]
synonym: "limonene 1,2-monooxygenase activity" EXACT []
xref: EC:1.14.13.107
+xref: KEGG_REACTION:R06398
+xref: KEGG_REACTION:R09385
+xref: KEGG_REACTION:R09389
+xref: KEGG_REACTION:R09393
+xref: MetaCyc:RXN-9407
+xref: MetaCyc:RXN-9408
+xref: MetaCyc:RXN-9409
+xref: RHEA:26085
+xref: RHEA:26089
+xref: RHEA:26093
+xref: RHEA:26097
+xref: UM-BBD_reactionID:r0733
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
is_a: GO:0019113 ! limonene monooxygenase activity
+property_value: skos:exactMatch EC:1.14.13.107
+property_value: skos:narrowMatch KEGG_REACTION:R06398
+property_value: skos:narrowMatch KEGG_REACTION:R09385
+property_value: skos:narrowMatch KEGG_REACTION:R09389
+property_value: skos:narrowMatch KEGG_REACTION:R09393
+property_value: skos:narrowMatch MetaCyc:RXN-9407
+property_value: skos:narrowMatch MetaCyc:RXN-9408
+property_value: skos:narrowMatch MetaCyc:RXN-9409
+property_value: skos:narrowMatch RHEA:26085
+property_value: skos:narrowMatch RHEA:26089
+property_value: skos:narrowMatch RHEA:26093
+property_value: skos:narrowMatch RHEA:26097
+property_value: skos:narrowMatch UM-BBD_reactionID:r0733
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27866" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28129" xsd:anyURI
@@ -344822,7 +358750,10 @@
xref: MetaCyc:RXN0-6444
xref: RHEA:31587
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.99.46
+property_value: skos:exactMatch RHEA:31587
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
creation_date: 2010-08-26T10:11:11Z
[Term]
@@ -344834,6 +358765,8 @@
xref: MetaCyc:1.14.13.78-RXN
xref: RHEA:32323
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.86
+property_value: skos:exactMatch RHEA:32323
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -344865,6 +358798,9 @@
xref: MetaCyc:RXN-8080
xref: RHEA:30555
is_a: GO:0043773 ! coenzyme F420-0 gamma-glutamyl ligase activity
+property_value: skos:exactMatch EC:6.3.2.31
+property_value: skos:exactMatch RHEA:30555
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052619
@@ -344875,6 +358811,9 @@
xref: MetaCyc:RXN-8081
xref: RHEA:30523
is_a: GO:0043773 ! coenzyme F420-0 gamma-glutamyl ligase activity
+property_value: skos:exactMatch EC:6.3.2.34
+property_value: skos:exactMatch RHEA:30523
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052620
@@ -344884,6 +358823,8 @@
xref: MetaCyc:RXN-8646
xref: RHEA:13469
is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups
+property_value: skos:broadMatch EC:1.17.99.4
+property_value: skos:exactMatch RHEA:13469
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -344898,6 +358839,9 @@
xref: MetaCyc:RXN0-5359
xref: RHEA:24898
is_a: GO:0016779 ! nucleotidyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.65
+property_value: skos:exactMatch RHEA:24898
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052622
@@ -344920,7 +358864,20 @@
synonym: "dimethylallyl-diphosphate:ADP dimethylallyltransferase activity" NARROW []
synonym: "dimethylallyl-diphosphate:ATP dimethylallyltransferase activity" NARROW []
xref: EC:2.5.1.112
+xref: KEGG_REACTION:R08051
+xref: KEGG_REACTION:R08052
+xref: MetaCyc:RXN-4303
+xref: MetaCyc:RXN-4305
+xref: RHEA:36327
+xref: RHEA:36331
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.112
+property_value: skos:narrowMatch KEGG_REACTION:R08051
+property_value: skos:narrowMatch KEGG_REACTION:R08052
+property_value: skos:narrowMatch MetaCyc:RXN-4303
+property_value: skos:narrowMatch MetaCyc:RXN-4305
+property_value: skos:narrowMatch RHEA:36327
+property_value: skos:narrowMatch RHEA:36331
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28059" xsd:anyURI
created_by: ai
creation_date: 2010-08-26T10:45:38Z
@@ -344957,7 +358914,10 @@
xref: RHEA:40551
is_a: GO:0008169 ! C-methyltransferase activity
is_a: GO:0008171 ! O-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.329
+property_value: skos:exactMatch RHEA:40551
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2010-08-26T12:00:06Z
@@ -344973,6 +358933,7 @@
synonym: "pABA amino acid synthetase activity" EXACT []
xref: MetaCyc:RXN-10884
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch MetaCyc:RXN-10884
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
[Term]
@@ -344984,6 +358945,7 @@
synonym: "benzoyl amino acid synthetase activity" EXACT []
xref: MetaCyc:RXN-10886
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch MetaCyc:RXN-10886
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
[Term]
@@ -344994,6 +358956,7 @@
synonym: "vanillate amino acid synthetase activity" BROAD []
xref: MetaCyc:RXN-10885
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch MetaCyc:RXN-10885
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
[Term]
@@ -345008,6 +358971,7 @@
synonym: "p-hydroxybenzoyl amino acid synthetase activity" EXACT []
xref: MetaCyc:RXN-10887
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch MetaCyc:RXN-10887
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
[Term]
@@ -345025,6 +358989,9 @@
xref: Reactome:R-HSA-6809944 "PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane"
xref: RHEA:39019
is_a: GO:0106018 ! phosphatidylinositol-3,5-bisphosphate phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.95
+property_value: skos:exactMatch RHEA:39019
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052630
@@ -345044,6 +359011,9 @@
xref: EC:2.7.7.83
xref: RHEA:34363
is_a: GO:0070569 ! uridylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.83
+property_value: skos:exactMatch RHEA:34363
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052631
@@ -345054,8 +359024,18 @@
synonym: "8-sphingolipid desaturase" EXACT [EC:1.14.19.29]
synonym: "sphingolipid delta-8 desaturase activity" EXACT []
xref: EC:1.14.19.29
+xref: MetaCyc:RXN-16375
+xref: MetaCyc:RXN-7798
+xref: RHEA:46268
+xref: RHEA:46272
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.29
+property_value: skos:narrowMatch MetaCyc:RXN-16375
+property_value: skos:narrowMatch MetaCyc:RXN-7798
+property_value: skos:narrowMatch RHEA:46268
+property_value: skos:narrowMatch RHEA:46272
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25968" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052633
@@ -345144,6 +359124,8 @@
xref: MetaCyc:RXN-11655
xref: RHEA:62708
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch RHEA:62708
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052639
@@ -345158,6 +359140,8 @@
xref: MetaCyc:RXN-11659
xref: RHEA:62316
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch RHEA:62316
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052640
@@ -345172,6 +359156,8 @@
xref: MetaCyc:RXN-11658
xref: RHEA:62312
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch RHEA:62312
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052641
@@ -345199,7 +359185,10 @@
xref: Reactome:R-HSA-8878654 "ACP6 hydrolyses MYS-LPA"
xref: RHEA:33155
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.106
+property_value: skos:exactMatch RHEA:33155
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26658" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052643
@@ -345314,7 +359303,10 @@
xref: RHEA:25033
is_a: GO:0008106 ! alcohol dehydrogenase (NADP+) activity
relationship: part_of GO:0042572 ! retinol metabolic process
+property_value: skos:exactMatch EC:1.1.1.300
+property_value: skos:exactMatch RHEA:25033
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052651
@@ -345365,6 +359357,7 @@
xref: MetaCyc:BRANCHED-CHAINAMINOTRANSFERLEU-RXN
xref: RHEA:18321
is_a: GO:0004084 ! branched-chain-amino-acid transaminase activity
+property_value: skos:exactMatch RHEA:18321
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
@@ -345379,6 +359372,7 @@
xref: MetaCyc:BRANCHED-CHAINAMINOTRANSFERVAL-RXN
xref: RHEA:24813
is_a: GO:0004084 ! branched-chain-amino-acid transaminase activity
+property_value: skos:exactMatch RHEA:24813
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -345392,6 +359386,7 @@
xref: MetaCyc:BRANCHED-CHAINAMINOTRANSFERILEU-RXN
xref: RHEA:24801
is_a: GO:0004084 ! branched-chain-amino-acid transaminase activity
+property_value: skos:exactMatch RHEA:24801
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -345415,6 +359410,8 @@
xref: MetaCyc:GUANPRIBOSYLTRAN-RXN
xref: RHEA:25424
is_a: GO:0106130 ! purine phosphoribosyltransferase activity
+property_value: skos:broadMatch EC:2.4.2.8
+property_value: skos:exactMatch RHEA:25424
[Term]
id: GO:0052658
@@ -345443,6 +359440,7 @@
xref: Reactome:R-HSA-1855222 "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane"
xref: RHEA:19797
is_a: GO:0004445 ! inositol-polyphosphate 5-phosphatase activity
+property_value: skos:exactMatch RHEA:19797
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -345463,6 +359461,7 @@
xref: RHEA:11392
is_a: GO:0004445 ! inositol-polyphosphate 5-phosphatase activity
is_a: GO:0052743 ! inositol tetrakisphosphate phosphatase activity
+property_value: skos:exactMatch RHEA:11392
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -345476,6 +359475,8 @@
xref: MetaCyc:RXN-8641
xref: RHEA:23872
is_a: GO:0008912 ! lactaldehyde reductase activity
+property_value: skos:exactMatch RHEA:23872
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052661
@@ -345488,6 +359489,8 @@
xref: MetaCyc:LACTALDREDUCT-RXN
xref: RHEA:15933
is_a: GO:0008912 ! lactaldehyde reductase activity
+property_value: skos:exactMatch RHEA:15933
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052662
@@ -345500,10 +359503,26 @@
synonym: "zea-epoxidase activity" RELATED [EC:1.14.15.21]
synonym: "zeaxanthin epoxidase [overall] activity" RELATED []
xref: EC:1.14.15.21
+xref: KEGG_REACTION:R06946
+xref: KEGG_REACTION:R06947
xref: KEGG_REACTION:R10070
xref: MetaCyc:RXN-13193
+xref: MetaCyc:RXN-7978
+xref: MetaCyc:RXN-7979
+xref: RHEA:14937
+xref: RHEA:24084
xref: RHEA:32443
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.15.21
+property_value: skos:exactMatch KEGG_REACTION:R10070
+property_value: skos:exactMatch MetaCyc:RXN-13193
+property_value: skos:exactMatch RHEA:32443
+property_value: skos:narrowMatch KEGG_REACTION:R06946
+property_value: skos:narrowMatch KEGG_REACTION:R06947
+property_value: skos:narrowMatch MetaCyc:RXN-7978
+property_value: skos:narrowMatch MetaCyc:RXN-7979
+property_value: skos:narrowMatch RHEA:14937
+property_value: skos:narrowMatch RHEA:24084
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28129" xsd:anyURI
@@ -345516,7 +359535,20 @@
synonym: "nitroalkane reductase activity" RELATED [EC:1.7.3.1]
synonym: "nitroalkane:oxygen oxidoreductase activity" RELATED [EC:1.7.3.1]
xref: EC:1.7.3.1
+xref: KEGG_REACTION:R00799
+xref: KEGG_REACTION:R10389
+xref: MetaCyc:NITROETHANE-OXIDASE-RXN
+xref: MetaCyc:RXN-11045
+xref: RHEA:20976
+xref: RHEA:26490
is_a: GO:0016663 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.7.3.1
+property_value: skos:narrowMatch KEGG_REACTION:R00799
+property_value: skos:narrowMatch KEGG_REACTION:R10389
+property_value: skos:narrowMatch MetaCyc:NITROETHANE-OXIDASE-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-11045
+property_value: skos:narrowMatch RHEA:20976
+property_value: skos:narrowMatch RHEA:26490
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
creation_date: 2010-10-11T10:50:59Z
@@ -345648,6 +359680,9 @@
xref: MetaCyc:RXN-9299
xref: RHEA:25544
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.31
+property_value: skos:exactMatch RHEA:25544
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052675
@@ -345663,7 +359698,9 @@
xref: RHEA:18525
is_a: GO:0008106 ! alcohol dehydrogenase (NADP+) activity
is_a: GO:0046568 ! 3-methylbutanal reductase [NAD(P)H] activity
+property_value: skos:exactMatch RHEA:18525
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-04-12T11:19:27Z
@@ -345681,7 +359718,9 @@
xref: RHEA:18529
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
is_a: GO:0046568 ! 3-methylbutanal reductase [NAD(P)H] activity
+property_value: skos:exactMatch RHEA:18529
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-04-12T11:22:42Z
@@ -345708,6 +359747,9 @@
xref: MetaCyc:RXN-8511
xref: RHEA:25548
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.32
+property_value: skos:exactMatch RHEA:25548
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052679
@@ -345719,6 +359761,9 @@
xref: MetaCyc:RXN-9455
xref: RHEA:25617
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.36
+property_value: skos:exactMatch RHEA:25617
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052680
@@ -345731,6 +359776,9 @@
xref: MetaCyc:RXN-9349
xref: RHEA:25992
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.37
+property_value: skos:exactMatch RHEA:25992
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052681
@@ -345744,6 +359792,9 @@
xref: MetaCyc:RXN-8550
xref: RHEA:25436
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.38
+property_value: skos:exactMatch RHEA:25436
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052682
@@ -345758,6 +359809,9 @@
xref: MetaCyc:RXN-10004
xref: RHEA:26115
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.39
+property_value: skos:exactMatch RHEA:26115
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052683
@@ -345769,6 +359823,9 @@
xref: MetaCyc:RXN-10005
xref: RHEA:26081
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.40
+property_value: skos:exactMatch RHEA:26081
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052684
@@ -345782,6 +359839,9 @@
xref: MetaCyc:RXN0-2382
xref: RHEA:26434
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.122
+property_value: skos:exactMatch RHEA:26434
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052685
@@ -345833,7 +359893,7 @@
alt_id: GO:0004302
alt_id: GO:0004759
alt_id: GO:0016789
-def: "Catalysis of the hydrolysis of a carboxylic ester bond." [GOC:curators]
+def: "Catalysis of the hydrolysis of a carboxylic ester bond." [EC:3.1.1.-, GOC:curators]
subset: goslim_drosophila
synonym: "carboxylate esterase activity" RELATED []
synonym: "carboxylic esterase activity" RELATED []
@@ -345845,7 +359905,9 @@
xref: Reactome:R-HSA-9749792 "CES1,CES2 hydrolyze ASA- to ST"
xref: UM-BBD_reactionID:r1025
is_a: GO:0016788 ! hydrolase activity, acting on ester bonds
+property_value: skos:exactMatch EC:3.1.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24654" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052690
@@ -345859,6 +359921,8 @@
xref: RHEA:56832
xref: UM-BBD_reactionID:r0315
is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond
+property_value: skos:exactMatch RHEA:56832
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052691
@@ -345874,6 +359938,9 @@
xref: MetaCyc:RXN-11552
xref: RHEA:28350
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.30
+property_value: skos:exactMatch RHEA:28350
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052692
@@ -345887,7 +359954,9 @@
xref: MetaCyc:RXN-11502
xref: RHEA:70275
is_a: GO:0004557 ! alpha-galactosidase activity
+property_value: skos:exactMatch RHEA:70275
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25223" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052693
@@ -345897,7 +359966,10 @@
xref: EC:1.17.99.6
xref: RHEA:32159
is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups
+property_value: skos:exactMatch EC:1.17.99.6
+property_value: skos:exactMatch RHEA:32159
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052694
@@ -345907,6 +359979,8 @@
xref: MetaCyc:RXN-12421
xref: RHEA:54808
is_a: GO:0004497 ! monooxygenase activity
+property_value: skos:exactMatch RHEA:54808
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052695
@@ -346098,9 +360172,31 @@
synonym: "S-adenosyl-L-methionine:L-histidine Nalpha-methyltransferase activity" EXACT [EC:2.1.1.44]
xref: EC:2.1.1.44
xref: KEGG_REACTION:R01169
+xref: KEGG_REACTION:R04436
+xref: KEGG_REACTION:R10523
+xref: KEGG_REACTION:R10524
+xref: MetaCyc:2.1.1.44-RXN
xref: MetaCyc:RXN-14431
+xref: MetaCyc:RXN-14437
+xref: MetaCyc:RXN-14438
+xref: RHEA:11104
xref: RHEA:38471
+xref: RHEA:38475
+xref: RHEA:38479
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.44
+property_value: skos:exactMatch KEGG_REACTION:R01169
+property_value: skos:exactMatch MetaCyc:RXN-14431
+property_value: skos:exactMatch RHEA:38471
+property_value: skos:narrowMatch KEGG_REACTION:R04436
+property_value: skos:narrowMatch KEGG_REACTION:R10523
+property_value: skos:narrowMatch KEGG_REACTION:R10524
+property_value: skos:narrowMatch MetaCyc:2.1.1.44-RXN
+property_value: skos:narrowMatch MetaCyc:RXN-14437
+property_value: skos:narrowMatch MetaCyc:RXN-14438
+property_value: skos:narrowMatch RHEA:11104
+property_value: skos:narrowMatch RHEA:38475
+property_value: skos:narrowMatch RHEA:38479
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28375" xsd:anyURI
created_by: ai
creation_date: 2011-08-05T11:57:40Z
@@ -346205,7 +360301,11 @@
name: inositol phosphosphingolipid phospholipase activity
namespace: molecular_function
def: "Catalysis of the reaction: inositol phosphosphingolipid + H2O = sphingolipid + phosphorylinositol." [GOC:ai]
-is_a: GO:0004629 ! phospholipase C activity
+xref: RHEA:55688
+is_a: GO:0120570 ! sphingophospholipase activity
+property_value: skos:narrowMatch RHEA:55688
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30258" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31030" xsd:anyURI
created_by: ai
creation_date: 2011-08-05T04:49:13Z
@@ -346249,6 +360349,9 @@
xref: MetaCyc:LACCASE-RXN
xref: RHEA:11276
is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.10.3.2
+property_value: skos:exactMatch RHEA:11276
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-08-11T03:18:19Z
@@ -346261,7 +360364,10 @@
xref: EC:3.5.4.33
xref: RHEA:43168
is_a: GO:0008251 ! tRNA-specific adenosine deaminase activity
+property_value: skos:exactMatch EC:3.5.4.33
+property_value: skos:exactMatch RHEA:43168
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24880" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-08-12T11:48:54Z
@@ -346325,6 +360431,8 @@
xref: MetaCyc:RXN-12186
xref: RHEA:45084
is_a: GO:0004497 ! monooxygenase activity
+property_value: skos:exactMatch RHEA:45084
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-08-15T01:41:07Z
@@ -346337,6 +360445,10 @@
xref: MetaCyc:RXN-10972
xref: RHEA:37459
is_a: GO:0000828 ! inositol hexakisphosphate kinase activity
+property_value: skos:broadMatch EC:2.7.4.21
+property_value: skos:exactMatch KEGG_REACTION:R05799
+property_value: skos:exactMatch MetaCyc:RXN-10972
+property_value: skos:exactMatch RHEA:37459
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
created_by: ai
creation_date: 2011-08-16T11:47:36Z
@@ -346348,6 +360460,7 @@
def: "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate." [MetaCyc:RXN-10971, PMID:18981179]
xref: MetaCyc:RXN-10971
is_a: GO:0000828 ! inositol hexakisphosphate kinase activity
+property_value: skos:exactMatch MetaCyc:RXN-10971
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
created_by: ai
creation_date: 2011-08-16T11:50:48Z
@@ -346369,6 +360482,10 @@
xref: Reactome:R-HSA-2267372 "ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4"
xref: RHEA:20940
is_a: GO:0051766 ! inositol trisphosphate kinase activity
+property_value: skos:broadMatch EC:2.7.1.159
+property_value: skos:exactMatch KEGG_REACTION:R03429
+property_value: skos:exactMatch MetaCyc:2.7.1.133-RXN
+property_value: skos:exactMatch RHEA:20940
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
created_by: ai
creation_date: 2011-08-16T12:42:59Z
@@ -346389,6 +360506,10 @@
xref: Reactome:R-HSA-994140 "ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4"
xref: RHEA:13253
is_a: GO:0051766 ! inositol trisphosphate kinase activity
+property_value: skos:broadMatch EC:2.7.1.159
+property_value: skos:exactMatch KEGG_REACTION:R03428
+property_value: skos:exactMatch MetaCyc:2.7.1.139-RXN
+property_value: skos:exactMatch RHEA:13253
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
created_by: ai
creation_date: 2011-08-16T12:43:11Z
@@ -346404,6 +360525,8 @@
xref: MetaCyc:RXN-7947
xref: RHEA:17373
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:broadMatch EC:5.3.99.8
+property_value: skos:exactMatch RHEA:17373
created_by: ai
creation_date: 2011-08-16T03:09:21Z
@@ -346419,6 +360542,8 @@
xref: MetaCyc:RXN-7946
xref: RHEA:21752
is_a: GO:0016860 ! intramolecular oxidoreductase activity
+property_value: skos:broadMatch EC:5.3.99.8
+property_value: skos:exactMatch RHEA:21752
created_by: ai
creation_date: 2011-08-16T03:09:26Z
@@ -346435,6 +360560,11 @@
xref: RHEA:10072
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.157
+property_value: skos:broadMatch EC:2.1.1.162
+property_value: skos:exactMatch EC:2.1.1.161
+property_value: skos:exactMatch MetaCyc:RXN-9680
+property_value: skos:exactMatch RHEA:10072
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
created_by: ai
@@ -346452,6 +360582,11 @@
xref: RHEA:15453
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.156
+property_value: skos:broadMatch EC:2.1.1.157
+property_value: skos:broadMatch EC:2.1.1.162
+property_value: skos:exactMatch MetaCyc:RXN-9679
+property_value: skos:exactMatch RHEA:15453
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
created_by: ai
@@ -346470,6 +360605,8 @@
xref: Reactome:R-HSA-1483159 "PCho is dephosphorylated to Cho by PHOSPHO1"
xref: RHEA:10492
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.75
+property_value: skos:exactMatch RHEA:10492
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
created_by: ai
creation_date: 2011-08-16T04:09:06Z
@@ -346487,6 +360624,8 @@
xref: Reactome:R-HSA-1483096 "PETA is dephosphorylated to ETA by PHOSPHO1"
xref: RHEA:16089
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.75
+property_value: skos:exactMatch RHEA:16089
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
created_by: ai
creation_date: 2011-08-16T04:09:19Z
@@ -346502,7 +360641,10 @@
xref: KEGG_REACTION:R06846
xref: RHEA:18425
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.1.1.282
+property_value: skos:exactMatch RHEA:18425
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-08-16T04:23:47Z
@@ -346521,7 +360663,10 @@
xref: KEGG_REACTION:R06847
xref: RHEA:17741
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.1.1.282
+property_value: skos:exactMatch RHEA:17741
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-08-16T04:28:23Z
@@ -346539,7 +360684,9 @@
synonym: "tRNA cytosine-3-methyltransferase activity" EXACT []
xref: RHEA:60908
is_a: GO:0016427 ! tRNA (cytidine) methyltransferase activity
+property_value: skos:exactMatch RHEA:60908
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25722" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052736
@@ -346564,6 +360711,9 @@
xref: MetaCyc:RXN-11496
xref: RHEA:27405
is_a: GO:0052738 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.2.5.1
+property_value: skos:exactMatch RHEA:27405
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052738
@@ -346572,6 +360722,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound." [EC:1.2.5.-]
xref: EC:1.2.5.-
is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors
+property_value: skos:exactMatch EC:1.2.5.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052739
@@ -346580,6 +360732,7 @@
def: "OBSOLETE. Catalysis of the reaction: phosphatidylserine + H2O = 2-acyl-sn-glycero-3-phosphoserine + fatty acid." [KEGG_REACTION:R04034]
comment: The reason for obsoletion is that this molecular function is equivalent to phospholipase A1 activity.
xref: KEGG_REACTION:R04034
+xref: Reactome:R-HSA-8869425 "PLA1A hydrolyses PS to 2-acyl LPS"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28816" xsd:anyURI
is_obsolete: true
replaced_by: GO:0008970
@@ -346608,8 +360761,11 @@
xref: RHEA:18957
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
is_a: GO:0019113 ! limonene monooxygenase activity
+property_value: skos:exactMatch EC:1.14.14.53
+property_value: skos:exactMatch RHEA:18957
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27866" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052742
@@ -346688,6 +360844,9 @@
xref: MetaCyc:RXN-11760
xref: RHEA:28130
is_a: GO:0046574 ! glucuronidase activity
+property_value: skos:exactMatch EC:3.2.1.167
+property_value: skos:exactMatch RHEA:28130
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30698" xsd:anyURI
created_by: ai
creation_date: 2011-09-21T12:58:43Z
@@ -346705,20 +360864,26 @@
xref: MetaCyc:RXN-11283
xref: RHEA:27294
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.98.2
+property_value: skos:exactMatch RHEA:27294
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-09-21T01:21:54Z
[Term]
id: GO:0052750
-name: reactive-black-5:hydrogen-peroxide oxidoreductase activity
+name: versatile peroxidase activity
namespace: molecular_function
-def: "Catalysis of the reaction: reactive black 5 + hydrogen peroxide = oxidized reactive black 5 + 2 H2O." [KEGG_REACTION:R07612, MetaCyc:RXN-8666]
-synonym: "versatile peroxidase activity" BROAD [EC:1.11.1.16]
+def: "Catalysis of the reaction: reactive black 5 + hydrogen peroxide = oxidized reactive black 5 + 2 H2O." [RHEA:22396]
+synonym: "reactive-black-5:hydrogen-peroxide oxidoreductase activity" BROAD [EC:1.11.1.16]
xref: EC:1.11.1.16
xref: KEGG_REACTION:R07612
xref: MetaCyc:RXN-8666
xref: RHEA:22396
is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch EC:1.11.1.16
+property_value: skos:exactMatch RHEA:22396
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-09-21T02:33:34Z
@@ -346764,6 +360929,7 @@
synonym: "GTP:coenzyme F420 guanylyltransferase activity" EXACT []
xref: MetaCyc:RXN-18273
is_a: GO:0070568 ! guanylyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-18273
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28503" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
@@ -346782,6 +360948,8 @@
xref: EC:1.1.98.4
xref: RHEA:39663
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch EC:1.1.98.4
+property_value: skos:exactMatch RHEA:39663
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
created_by: ai
creation_date: 2011-09-22T04:08:13Z
@@ -346857,6 +361025,8 @@
xref: KEGG_REACTION:R08715
xref: MetaCyc:3.2.1.165-RXN
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.165
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-09-28T03:30:54Z
@@ -346868,6 +361038,8 @@
xref: EC:4.2.2.25
xref: MetaCyc:RXN-12269
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.25
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-09-29T03:19:25Z
@@ -346887,6 +361059,8 @@
def: "Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends." [GOC:mengo_curators, PMID:20925655]
xref: EC:4.2.2.26
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.26
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-09-29T04:05:44Z
@@ -346901,6 +361075,8 @@
xref: EC:1.5.3.22
xref: RHEA:39711
is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.5.3.22
+property_value: skos:exactMatch RHEA:39711
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
created_by: ai
creation_date: 2011-09-29T04:33:54Z
@@ -347005,6 +361181,9 @@
xref: MetaCyc:RXN-12543
xref: RHEA:62168
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.136
+property_value: skos:exactMatch MetaCyc:RXN-12543
+property_value: skos:exactMatch RHEA:62168
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
created_by: ai
creation_date: 2011-10-03T12:01:05Z
@@ -347346,12 +361525,19 @@
id: GO:0052806
name: sulfite reductase (coenzyme F420) activity
namespace: molecular_function
-def: "Catalysis of the reaction: sulfite + 3 1,5-dihydrocoenzyme F420 = hydrogen sulfide + 3 H2O + 3 coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420." [GOC:mengo_curators, PMID:16048999]
+def: "Catalysis of the reaction: 3 oxidized coenzyme F420-(gamma-L-Glu)(n) + hydrogen sulfide + 3 H2O + 2 H+ = 3 reduced coenzyme F420-(gamma-L-Glu)(n) + sulfite." [PMID:16048999, RHEA:42808]
synonym: "coenzyme F420-dependent sulfite reductase activity" EXACT []
synonym: "coenzyme F420-sulfite reductase activity" EXACT []
synonym: "hydrogen-sulfide:coenzyme F420 oxidoreductase activity" EXACT []
synonym: "sulfite:reduced coenzyme F420 reductase activity" EXACT []
-is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors
+xref: EC:1.8.98.3
+xref: MetaCyc:RXN-15618
+xref: RHEA:42808
+is_a: GO:0016002 ! sulfite reductase activity
+property_value: skos:exactMatch EC:1.8.98.3
+property_value: skos:exactMatch MetaCyc:RXN-15618
+property_value: skos:exactMatch RHEA:42808
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: ai
creation_date: 2011-09-22T04:08:13Z
@@ -347405,7 +361591,9 @@
xref: Reactome:R-HSA-1675866 "PI is phosphorylated to PI5P by PIKFYVE at the late endosome membrane"
xref: RHEA:44680
is_a: GO:0052742 ! phosphatidylinositol kinase activity
+property_value: skos:exactMatch RHEA:44680
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28336" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-10-21T03:37:20Z
@@ -347419,6 +361607,8 @@
xref: Reactome:R-HSA-1676145 "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane"
xref: RHEA:63688
is_a: GO:0052742 ! phosphatidylinositol kinase activity
+property_value: skos:exactMatch MetaCyc:RXN-10957
+property_value: skos:exactMatch RHEA:63688
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28333" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28336" xsd:anyURI
created_by: ai
@@ -347460,8 +361650,10 @@
synonym: "medium-chain-aldehyde:NAD+ oxidoreductase activity" RELATED []
xref: RHEA:69763
is_a: GO:0102673 ! fatty aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch RHEA:69763
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28090" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28142" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
creation_date: 2011-10-25T03:04:41Z
[Term]
@@ -347474,11 +361666,15 @@
synonym: "medium-chain acyl-thioester hydrolase activity" RELATED []
synonym: "medium-chain hydrolase activity" RELATED []
synonym: "medium-chain-acyl-CoA hydrolase activity" RELATED []
+xref: EC:3.1.2.19
xref: MetaCyc:3.1.2.19-RXN
xref: RHEA:68184
is_a: GO:0047617 ! fatty acyl-CoA hydrolase activity
+property_value: skos:exactMatch RHEA:68184
+property_value: skos:narrowMatch EC:3.1.2.19
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26441" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-10-25T05:26:29Z
@@ -347494,8 +361690,10 @@
synonym: "long-chain-acyl-CoA hydrolase activity" RELATED []
xref: RHEA:67680
is_a: GO:0047617 ! fatty acyl-CoA hydrolase activity
+property_value: skos:exactMatch RHEA:67680
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26441" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-10-25T05:31:11Z
@@ -347511,8 +361709,10 @@
synonym: "very long-chain-acyl-CoA hydrolase activity" RELATED []
xref: RHEA:67072
is_a: GO:0047617 ! fatty acyl-CoA hydrolase activity
+property_value: skos:exactMatch RHEA:67072
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26441" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-10-27T12:18:28Z
@@ -347558,6 +361758,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site." [GOC:jl, PMID:16468998]
is_a: GO:0003905 ! alkylbase DNA N-glycosylase activity
+property_value: skos:broadMatch EC:3.2.2.21
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
created_by: ai
@@ -347569,6 +361770,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site." [GOC:elh, PMID:10872450, PMID:9224623]
is_a: GO:0043733 ! DNA-3-methylbase glycosylase activity
+property_value: skos:broadMatch EC:3.2.2.21
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24405" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
@@ -347586,7 +361788,9 @@
xref: MetaCyc:RXN-12070
xref: RHEA:34191
xref: UM-BBD_reactionID:r1622
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:broadMatch EC:3.7.1.14
+property_value: skos:exactMatch RHEA:34191
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
created_by: ai
creation_date: 2011-10-28T03:28:37Z
@@ -347606,6 +361810,7 @@
namespace: molecular_function
def: "OBSOLETE. Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate." [GOC:curators]
comment: The reason for obsoletion is that this term is equivalent to inositol hexakisphosphate 3-phosphatase activity.
+xref: Reactome:R-HSA-1855225 "IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30385" xsd:anyURI
is_obsolete: true
@@ -347630,6 +361835,8 @@
xref: Reactome:R-HSA-1855202 "I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol"
xref: RHEA:43388
is_a: GO:0016312 ! inositol bisphosphate phosphatase activity
+property_value: skos:exactMatch RHEA:43388
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-11-29T09:57:00Z
@@ -347672,7 +361879,9 @@
xref: Reactome:R-HSA-1855210 "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol"
xref: RHEA:30739
is_a: GO:0052834 ! inositol monophosphate phosphatase activity
+property_value: skos:exactMatch RHEA:30739
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-11-29T11:00:09Z
@@ -347688,7 +361897,9 @@
xref: Reactome:R-HSA-1855211 "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol"
xref: RHEA:30735
is_a: GO:0052834 ! inositol monophosphate phosphatase activity
+property_value: skos:exactMatch RHEA:30735
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-11-29T11:02:15Z
@@ -347710,7 +361921,10 @@
xref: MetaCyc:RXN-10949
xref: RHEA:24056
is_a: GO:0052745 ! inositol phosphate phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.25
+property_value: skos:exactMatch RHEA:24056
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-11-29T11:15:58Z
@@ -347729,7 +361943,9 @@
xref: Reactome:R-HSA-1855169 "I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol"
xref: RHEA:70287
is_a: GO:0051766 ! inositol trisphosphate kinase activity
+property_value: skos:exactMatch RHEA:70287
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21631" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-11-29T01:06:01Z
@@ -347854,7 +362070,9 @@
xref: MetaCyc:RXN-10964
xref: RHEA:22384
is_a: GO:0052842 ! inositol diphosphate pentakisphosphate diphosphatase activity
+property_value: skos:exactMatch RHEA:22384
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24181" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-12-05T10:59:20Z
@@ -347890,6 +362108,8 @@
xref: MetaCyc:RXN-10976
xref: RHEA:56312
is_a: GO:0052841 ! inositol bisdiphosphate tetrakisphosphate diphosphatase activity
+property_value: skos:exactMatch RHEA:56312
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2011-12-05T11:02:23Z
@@ -347902,6 +362122,8 @@
xref: MetaCyc:RXN0-6676
xref: RHEA:34815
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.3.1.n3
+property_value: skos:exactMatch RHEA:34815
created_by: ai
creation_date: 2011-12-05T11:03:23Z
@@ -347931,11 +362153,13 @@
xref: KEGG_REACTION:R09541
xref: MetaCyc:RXN0-6555
xref: Reactome:R-HSA-917811 "STEAP3,STEAP4 reduce Fe3+ to Fe2+"
-xref: Reactome:R-HSA-9927945 "YqjH reduces FeEnt"
xref: RHEA:28795
is_a: GO:0000293 ! ferric-chelate reductase activity
is_a: GO:0016723 ! oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.16.1.9
+property_value: skos:exactMatch RHEA:28795
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21029" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
created_by: ai
creation_date: 2011-12-05T11:04:23Z
@@ -347950,7 +362174,12 @@
synonym: "ADP-dependent H(4)NAD(P)OH dehydratase activity" EXACT []
synonym: "ADP-dependent H4NAD(P)OH dehydratase activity" EXACT []
xref: EC:4.2.1.136
+xref: RHEA:32223
+xref: RHEA:32235
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.136
+property_value: skos:narrowMatch RHEA:32223
+property_value: skos:narrowMatch RHEA:32235
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
[Term]
@@ -347961,8 +362190,12 @@
synonym: "NADHX epimerase activity" NARROW []
synonym: "NADPHX epimerase activity" NARROW []
xref: EC:5.1.99.6
-xref: Reactome:R-HSA-6806966 "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX"
+xref: RHEA:32215
+xref: RHEA:32227
is_a: GO:0016854 ! racemase and epimerase activity
+property_value: skos:exactMatch EC:5.1.99.6
+property_value: skos:narrowMatch RHEA:32215
+property_value: skos:narrowMatch RHEA:32227
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -347971,6 +362204,7 @@
namespace: molecular_function
def: "OBSOLETE. Catalysis of the reaction: (R)-NADPHX = (S)-NADPHX." [PMID:21994945]
comment: This term was obsoleted because it represents the same activity as NADHX epimerase activity ; GO:0052856.
+xref: Reactome:R-HSA-6806966 "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
is_obsolete: true
replaced_by: GO:0052856
@@ -348038,6 +362272,7 @@
xref: EC:3.2.1.6
xref: MetaCyc:3.2.1.6-RXN
is_a: GO:0052736 ! beta-glucanase activity
+property_value: skos:exactMatch EC:3.2.1.6
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28308" xsd:anyURI
created_by: ai
creation_date: 2011-12-06T04:49:36Z
@@ -348147,6 +362382,7 @@
xref: MetaCyc:RXN-19677
xref: RHEA:39755
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:39755
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28648" xsd:anyURI
created_by: ai
@@ -348174,7 +362410,9 @@
xref: MetaCyc:RXN-11003
xref: RHEA:45108
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:45108
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27862" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ai
creation_date: 2012-01-30T03:06:27Z
@@ -348202,6 +362440,8 @@
xref: Reactome:R-HSA-1222399 "Iron is reduced and separates from mycobactin"
xref: RHEA:21624
is_a: GO:0008752 ! FMN reductase [NAD(P)H] activity
+property_value: skos:exactMatch EC:1.5.1.38
+property_value: skos:exactMatch RHEA:21624
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16166" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
@@ -348217,6 +362457,8 @@
xref: KEGG_REACTION:R05705
xref: RHEA:21620
is_a: GO:0008752 ! FMN reductase [NAD(P)H] activity
+property_value: skos:exactMatch EC:1.5.1.42
+property_value: skos:exactMatch RHEA:21620
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
[Term]
@@ -348240,7 +362482,10 @@
xref: EC:1.5.1.41
xref: KEGG_REACTION:R09750
xref: MetaCyc:RXN-12445
+xref: RHEA:31455
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.41
+property_value: skos:narrowMatch RHEA:31455
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16166" xsd:anyURI
[Term]
@@ -348258,7 +362503,10 @@
xref: RHEA:30207
xref: UM-BBD_reactionID:r0075
is_a: GO:0052877 ! oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor
+property_value: skos:exactMatch EC:1.4.9.1
+property_value: skos:exactMatch RHEA:30207
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21650" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052877
@@ -348267,6 +362515,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and a copper protein is the acceptor." [GOC:ai]
xref: EC:1.4.9.-
is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors
+property_value: skos:exactMatch EC:1.4.9.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052878
@@ -348283,6 +362533,9 @@
xref: MetaCyc:RXN-12756
xref: RHEA:25395
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.60
+property_value: skos:exactMatch RHEA:25395
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052879
@@ -348297,6 +362550,9 @@
xref: MetaCyc:RXN-12758
xref: RHEA:25399
is_a: GO:0050486 ! intramolecular hydroxytransferase activity
+property_value: skos:exactMatch EC:5.4.4.6
+property_value: skos:exactMatch RHEA:25399
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052880
@@ -348305,6 +362561,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a copper protein." [GOC:jl]
xref: EC:1.10.9.-
is_a: GO:0016679 ! oxidoreductase activity, acting on diphenols and related substances as donors
+property_value: skos:exactMatch EC:1.10.9.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052881
@@ -348323,6 +362581,9 @@
xref: RHEA:30595
xref: UM-BBD_reactionID:r0301
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.9
+property_value: skos:exactMatch RHEA:30595
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052882
@@ -348331,6 +362592,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a copper protein." [GOC:jl]
xref: EC:1.20.9.-
is_a: GO:0030613 ! oxidoreductase activity, acting on phosphorus or arsenic in donors
+property_value: skos:exactMatch EC:1.20.9.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052883
@@ -348343,6 +362606,9 @@
xref: EC:4.3.1.23
xref: RHEA:24906
is_a: GO:0016841 ! ammonia-lyase activity
+property_value: skos:broadMatch EC:4.3.1.25
+property_value: skos:exactMatch EC:4.3.1.23
+property_value: skos:exactMatch RHEA:24906
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
[Term]
@@ -348357,6 +362623,8 @@
xref: Reactome:R-HSA-2453833 "RPE65 isomero-hydrolyses atREs to 11cROL"
xref: RHEA:31775
is_a: GO:0050253 ! retinyl-palmitate esterase activity
+property_value: skos:broadMatch EC:3.1.1.64
+property_value: skos:exactMatch RHEA:31775
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -348374,6 +362642,8 @@
xref: RHEA:31771
is_a: GO:0052689 ! carboxylic ester hydrolase activity
relationship: part_of GO:0042572 ! retinol metabolic process
+property_value: skos:broadMatch EC:3.1.1.64
+property_value: skos:exactMatch RHEA:31771
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -348431,6 +362701,8 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a flavin." [EC:1.3.8.-]
xref: EC:1.3.8.-
is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors
+property_value: skos:exactMatch EC:1.3.8.-
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052891
@@ -348443,7 +362715,11 @@
synonym: "(S)-oxynitrilase activity" BROAD [EC:4.1.2.47]
synonym: "(S)-selective hydroxynitrile lyase activity" BROAD [EC:4.1.2.47]
xref: MetaCyc:RXN-11731
+xref: RHEA:56588
+xref: RHEA:56592
is_a: GO:0047606 ! (S)-hydroxynitrile lyase activity
+property_value: skos:narrowMatch RHEA:56588
+property_value: skos:narrowMatch RHEA:56592
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16166" xsd:anyURI
[Term]
@@ -348455,7 +362731,9 @@
xref: MetaCyc:RXN-11732
xref: RHEA:54660
is_a: GO:0047606 ! (S)-hydroxynitrile lyase activity
+property_value: skos:exactMatch RHEA:54660
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16166" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052893
@@ -348514,6 +362792,8 @@
xref: MetaCyc:RXN-10463
xref: RHEA:25972
is_a: GO:0046592 ! polyamine oxidase activity
+property_value: skos:exactMatch EC:1.5.3.15
+property_value: skos:exactMatch RHEA:25972
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24701" xsd:anyURI
[Term]
@@ -348544,8 +362824,14 @@
synonym: "polyamine oxidase (propane-1,3-diamine-forming) activity" BROAD [EC:1.5.3.14]
xref: EC:1.5.3.14
xref: MetaCyc:RXN-6421
+xref: RHEA:25820
xref: RHEA:25824
+xref: RHEA:25996
is_a: GO:0046592 ! polyamine oxidase activity
+property_value: skos:exactMatch EC:1.5.3.14
+property_value: skos:exactMatch RHEA:25824
+property_value: skos:narrowMatch RHEA:25820
+property_value: skos:narrowMatch RHEA:25996
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24701" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
@@ -348560,7 +362846,11 @@
xref: MetaCyc:RXN-9015
xref: Reactome:R-HSA-141341 "SMOX-3 oxidises SPN to SPM"
xref: RHEA:25804
+xref: RHEA:25816
is_a: GO:0046592 ! polyamine oxidase activity
+property_value: skos:exactMatch EC:1.5.3.16
+property_value: skos:exactMatch RHEA:25804
+property_value: skos:narrowMatch RHEA:25816
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24701" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25837" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28514" xsd:anyURI
@@ -348588,9 +362878,17 @@
xref: EC:1.5.3.13
xref: KEGG_REACTION:R03899
xref: MetaCyc:RXN-12090
-xref: Reactome:R-HSA-141348 "PAO:FAD oxidises NASPM to PTCN"
-xref: Reactome:R-HSA-141351 "PAOX:FAD oxidises NASPN to SPM"
+xref: RHEA:25800
+xref: RHEA:25812
+xref: RHEA:25868
is_a: GO:0046592 ! polyamine oxidase activity
+property_value: skos:exactMatch EC:1.5.3.13
+property_value: skos:exactMatch KEGG_REACTION:R03899
+property_value: skos:exactMatch MetaCyc:RXN-12090
+property_value: skos:narrowMatch RHEA:25800
+property_value: skos:narrowMatch RHEA:25812
+property_value: skos:narrowMatch RHEA:25868
+property_value: skos:relatedMatch MetaCyc:RXN-9940
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24701" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25837" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
@@ -348602,6 +362900,8 @@
namespace: molecular_function
def: "OBSOLETE. Catalysis of the reaction: H2O + N(1)-acetylspermidine + O2 = 3-acetamidopropanal + H2O2 + putrescine." [GOC:curators]
comment: This term was obsoleted because it represents a specific substrate of N(1)-acetylpolyamine oxidase (3-acetamidopropanal-forming) activity ; GO:0052903.
+xref: Reactome:R-HSA-141348 "PAO:FAD oxidises NASPM to PTCN"
+xref: Reactome:R-HSA-141351 "PAOX:FAD oxidises NASPN to SPM"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24701" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
is_obsolete: true
@@ -348626,7 +362926,10 @@
xref: Reactome:R-HSA-6787591 "TRMT10C:HSD17B10 (TRMT10C:SDR5C1) of mitochondrial RNase P methylates guanosine-9 in tRNA yielding 1-methylguanosine-9"
xref: RHEA:43156
is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.221
+property_value: skos:exactMatch RHEA:43156
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26085" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052906
@@ -348644,7 +362947,10 @@
xref: Reactome:R-HSA-6782859 "TRMT5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe)"
xref: RHEA:36899
is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.228
+property_value: skos:exactMatch RHEA:36899
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26085" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052907
@@ -348658,6 +362964,9 @@
xref: MetaCyc:RXN-11596
xref: RHEA:16497
is_a: GO:0008988 ! rRNA (adenine-N6-)-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.181
+property_value: skos:exactMatch RHEA:16497
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052908
@@ -348669,7 +362978,10 @@
xref: MetaCyc:RXN-11633
xref: RHEA:19609
is_a: GO:0000179 ! rRNA (adenine-N6,N6-)-dimethyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.182
+property_value: skos:exactMatch RHEA:19609
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14459" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052909
@@ -348681,7 +362993,10 @@
xref: MetaCyc:RXN-11634
xref: RHEA:42780
is_a: GO:0000179 ! rRNA (adenine-N6,N6-)-dimethyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.183
+property_value: skos:exactMatch RHEA:42780
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14459" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052910
@@ -348695,6 +363010,9 @@
xref: MetaCyc:RXN-11597
xref: RHEA:42784
is_a: GO:0008988 ! rRNA (adenine-N6-)-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.184
+property_value: skos:exactMatch RHEA:42784
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052911
@@ -348711,7 +363029,10 @@
xref: MetaCyc:RXN-11573
xref: RHEA:42900
is_a: GO:0008989 ! rRNA (guanine-N1-)-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.187
+property_value: skos:exactMatch RHEA:42900
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052912
@@ -348723,7 +363044,10 @@
xref: MetaCyc:RXN-11599
xref: RHEA:42904
is_a: GO:0008989 ! rRNA (guanine-N1-)-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.188
+property_value: skos:exactMatch RHEA:42904
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052913
@@ -348734,7 +363058,10 @@
xref: MetaCyc:RXN0-6515
xref: RHEA:23548
is_a: GO:0008990 ! rRNA (guanine-N2-)-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.171
+property_value: skos:exactMatch RHEA:23548
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052914
@@ -348746,7 +363073,10 @@
xref: MetaCyc:RXN-11576
xref: RHEA:42736
is_a: GO:0008990 ! rRNA (guanine-N2-)-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.172
+property_value: skos:exactMatch RHEA:42736
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052915
@@ -348757,7 +363087,10 @@
xref: MetaCyc:RXN-11574
xref: RHEA:42740
is_a: GO:0008990 ! rRNA (guanine-N2-)-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.173
+property_value: skos:exactMatch RHEA:42740
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052916
@@ -348768,7 +363101,10 @@
xref: MetaCyc:RXN-11635
xref: RHEA:42744
is_a: GO:0008990 ! rRNA (guanine-N2-)-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.174
+property_value: skos:exactMatch RHEA:42744
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052917
@@ -348784,7 +363120,10 @@
xref: RHEA:29535
is_a: GO:0000009 ! alpha-1,6-mannosyltransferase activity
is_a: GO:0120562 ! GlcNAc(2)-PP-Dol mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.260
+property_value: skos:exactMatch RHEA:29535
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19075" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30326" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30456" xsd:anyURI
@@ -348799,6 +363138,9 @@
xref: RHEA:29539
is_a: GO:0000026 ! alpha-1,2-mannosyltransferase activity
is_a: GO:0120562 ! GlcNAc(2)-PP-Dol mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.261
+property_value: skos:exactMatch RHEA:29539
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30326" xsd:anyURI
[Term]
@@ -348810,10 +363152,14 @@
synonym: "(R)-hydroxynitrile lyase activity" BROAD [EC:4.1.2.46]
synonym: "(R)-oxynitrilase activity" BROAD [EC:4.1.2.46]
xref: EC:4.1.2.46
+xref: RHEA:28170
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.46
+property_value: skos:narrowMatch RHEA:28170
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16166" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052920
@@ -348849,7 +363195,10 @@
xref: MetaCyc:RXN-11485
xref: RHEA:27555
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.82
+property_value: skos:exactMatch RHEA:27555
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052923
@@ -348878,9 +363227,12 @@
xref: MetaCyc:TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN
xref: RHEA:27563
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.84
+property_value: skos:exactMatch RHEA:27563
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/12432" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23417" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052924
@@ -348895,7 +363247,10 @@
xref: MetaCyc:RXN-11486
xref: RHEA:27594
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.85
+property_value: skos:exactMatch RHEA:27594
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052925
@@ -348910,6 +363265,9 @@
xref: RHEA:29527
is_a: GO:0000033 ! alpha-1,3-mannosyltransferase activity
is_a: GO:0120562 ! GlcNAc(2)-PP-Dol mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.258
+property_value: skos:exactMatch RHEA:29527
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30326" xsd:anyURI
[Term]
@@ -348924,6 +363282,9 @@
xref: RHEA:29531
is_a: GO:0000026 ! alpha-1,2-mannosyltransferase activity
is_a: GO:0120562 ! GlcNAc(2)-PP-Dol mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.259
+property_value: skos:exactMatch RHEA:29531
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30326" xsd:anyURI
[Term]
@@ -348935,9 +363296,14 @@
synonym: "CC-adding tRNA nucleotidyltransferase activity" EXACT []
synonym: "CTP:3'-cytidine-tRNA cytidylyltransferase activity" RELATED []
synonym: "CTP:tRNA cytidylyltransferase activity" EXACT []
+xref: KEGG_REACTION:R09383
+xref: KEGG_REACTION:R09384
xref: RHEA:60008
is_a: GO:0070567 ! cytidylyltransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch RHEA:60008
+property_value: skos:narrowMatch KEGG_REACTION:R09383
+property_value: skos:narrowMatch KEGG_REACTION:R09384
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19854" xsd:anyURI
[Term]
@@ -348951,8 +363317,10 @@
xref: RHEA:60012
is_a: GO:0070566 ! adenylyltransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch RHEA:60012
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17855" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19854" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0052933
@@ -348970,8 +363338,14 @@
xref: EC:1.1.2.7
xref: KEGG_REACTION:R10713
xref: MetaCyc:RXN-11332
+xref: MetaCyc:RXN-2861
xref: RHEA:51004
is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.1.2.7
+property_value: skos:exactMatch KEGG_REACTION:R10713
+property_value: skos:exactMatch MetaCyc:RXN-11332
+property_value: skos:exactMatch RHEA:51004
+property_value: skos:narrowMatch MetaCyc:RXN-2861
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -348997,7 +363371,10 @@
xref: MetaCyc:RXN-11333
xref: RHEA:51020
is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.1.2.8
+property_value: skos:exactMatch RHEA:51020
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0055001
@@ -349407,6 +363784,9 @@
xref: MetaCyc:CYCLOPENTANOL-DEHYDROGENASE-RXN
xref: RHEA:11728
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.163
+property_value: skos:exactMatch RHEA:11728
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0055042
@@ -349535,11 +363915,9 @@
def: "Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other." [GOC:jid, GOC:jsg, GOC:mah]
xref: Reactome:R-HSA-429094 "SLC2A6,8,10,12 transport Glc from extracellular region to cytosol"
xref: Reactome:R-HSA-450095 "GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region"
-xref: Reactome:R-HSA-499981 "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2"
xref: Reactome:R-HSA-5339524 "GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol"
xref: Reactome:R-HSA-5632804 "SLC2A1 tetramer does not transport Glc from extracellular region to cytosol"
xref: Reactome:R-HSA-5632871 "Defective SLC2A10 does not transport Glc from extracellular region to cytosol"
-xref: Reactome:R-HSA-5653873 "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen"
xref: Reactome:R-HSA-8981553 "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol"
xref: Reactome:R-HSA-8981564 "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol"
xref: Reactome:R-HSA-8981570 "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol"
@@ -349905,7 +364283,7 @@
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus." [GOC:BHF, GOC:rl]
synonym: "response to lipoprotein particle stimulus" EXACT [GOC:dos]
is_a: GO:0009719 ! response to endogenous stimulus
-is_a: GO:1901698 ! response to nitrogen compound
+is_a: GO:0042221 ! response to chemical
[Term]
id: GO:0055095
@@ -350008,11 +364386,13 @@
[Term]
id: GO:0055108
-name: Golgi to transport vesicle transport
+name: obsolete Golgi to transport vesicle transport
namespace: biological_process
-def: "The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis." [GOC:jid]
-is_a: GO:0046907 ! intracellular transport
-relationship: part_of GO:0048193 ! Golgi vesicle transport
+def: "OBSOLETE. The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis." [GOC:jid]
+comment: The reason for obsoletion is that this term is equivalent to Golgi to plasma membrane transport.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31204" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0006893
[Term]
id: GO:0055109
@@ -350044,13 +364424,14 @@
[Term]
id: GO:0055112
-name: delamination involved in gastrulation with mouth forming second
+name: obsolete delamination involved in gastrulation with mouth forming second
namespace: biological_process
-def: "The splitting or migration of one epithelial sheet into two involved in the process of deuterostomic gastrulation." [ISBN:0878932437]
-is_a: GO:0060232 ! delamination
-intersection_of: GO:0060232 ! delamination
-intersection_of: part_of GO:0001702 ! gastrulation with mouth forming second
-relationship: part_of GO:0001702 ! gastrulation with mouth forming second
+def: "OBSOLETE. The splitting or migration of one epithelial sheet into two involved in the process of deuterostomic gastrulation." [ISBN:0878932437]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001702
+consider: GO:0060232
[Term]
id: GO:0055113
@@ -350197,9 +364578,15 @@
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins." [GOC:ecd]
synonym: "pyrrolidine-2-carboxylic acid biosynthetic process" BROAD []
+xref: MetaCyc:PROSYN-PWY
+xref: MetaCyc:PWY-3341
xref: MetaCyc:PWY-4281 {status="skos:narrowMatch"}
-is_a: GO:0006560 ! proline metabolic process
-is_a: GO:0009084 ! glutamine family amino acid biosynthetic process
+xref: MetaCyc:PWY-4981
+is_a: GO:0006560 ! L-proline metabolic process
+is_a: GO:0009084 ! L-glutamine family amino acid biosynthetic process
+property_value: skos:narrowMatch MetaCyc:PROSYN-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-3341
+property_value: skos:narrowMatch MetaCyc:PWY-4981
created_by: jid
creation_date: 2009-10-22T01:59:56Z
@@ -350209,7 +364596,6 @@
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of D-alanine, the D-enantiomer of the amino acid alanine." [GOC:ecd]
synonym: "(2R)-2-aminopropanoic acid catabolic process" EXACT []
-is_a: GO:0006524 ! alanine catabolic process
is_a: GO:0019478 ! D-amino acid catabolic process
is_a: GO:0046436 ! D-alanine metabolic process
created_by: jid
@@ -351092,7 +365478,6 @@
synonym: "binding, bridging" EXACT []
synonym: "protein complex scaffold activity" BROAD []
synonym: "protein-containing complex scaffold activity" BROAD []
-xref: Reactome:R-HSA-2564826 "4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold"
is_a: GO:0003674 ! molecular_function
relationship: has_part GO:0005488 ! binding
@@ -351970,8 +366355,10 @@
is_a: GO:0005030 ! neurotrophin receptor activity
relationship: has_part GO:0048403 ! brain-derived neurotrophic factor binding
relationship: part_of GO:0031547 ! brain-derived neurotrophic factor receptor signaling pathway
+property_value: skos:broadMatch EC:2.7.10.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23056" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
[Term]
id: GO:0060176
@@ -352466,14 +366853,15 @@
[Term]
id: GO:0060227
-name: Notch signaling pathway involved in camera-type eye photoreceptor fate commitment
+name: obsolete Notch signaling pathway involved in camera-type eye photoreceptor fate commitment
namespace: biological_process
-def: "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate." [GOC:dph]
+def: "OBSOLETE. The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate." [GOC:dph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "Notch signalling pathway involved in camera-type eye photoreceptor fate commitment" EXACT [GOC:mah]
-is_a: GO:0007219 ! Notch signaling pathway
-intersection_of: GO:0007219 ! Notch signaling pathway
-intersection_of: part_of GO:0060220 ! camera-type eye photoreceptor cell fate commitment
-relationship: part_of GO:0060220 ! camera-type eye photoreceptor cell fate commitment
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007219
+consider: GO:0060220
[Term]
id: GO:0060228
@@ -352489,7 +366877,6 @@
name: lipase activator activity
namespace: molecular_function
def: "Binds to and increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid." [GOC:BHF, GOC:dph, GOC:tb]
-xref: Reactome:R-HSA-163549 "phosphorylated HSL dimer + FABP4 -> phosphorylated HSL dimer:FABP4 complex"
is_a: GO:0008047 ! enzyme activator activity
relationship: positively_regulates GO:0016298 ! lipase activity
@@ -353546,11 +367933,13 @@
[Term]
id: GO:0060329
-name: cytoplasmic actin-based contraction involved in rearward cell motility
+name: obsolete cytoplasmic actin-based contraction involved in rearward cell motility
namespace: biological_process
-def: "The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell." [GOC:dph]
+def: "OBSOLETE. The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell." [GOC:dph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "cytoplasmic actin-based contraction involved in rearward cell locomotion" RELATED []
-is_a: GO:0060327 ! cytoplasmic actin-based contraction involved in cell motility
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0060330
@@ -353918,14 +368307,14 @@
[Term]
id: GO:0060362
-name: flight involved in flight behavior
+name: obsolete flight involved in flight behavior
namespace: biological_process
-def: "Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight." [GOC:dph]
-is_a: GO:0031987 ! locomotion involved in locomotory behavior
-is_a: GO:0060361 ! flight
-intersection_of: GO:0060361 ! flight
-intersection_of: part_of GO:0007629 ! flight behavior
-relationship: part_of GO:0007629 ! flight behavior
+def: "OBSOLETE. Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight." [GOC:dph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007629
+consider: GO:0060361
[Term]
id: GO:0060363
@@ -354511,6 +368900,7 @@
name: peptidyl-dipeptidase inhibitor activity
namespace: molecular_function
def: "Binds to and stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain." [GOC:dph, GOC:tb]
+xref: Wikipedia:ACE_inhibitor
is_a: GO:0030414 ! peptidase inhibitor activity
relationship: negatively_regulates GO:0008241 ! peptidyl-dipeptidase activity
@@ -355186,16 +369576,15 @@
[Term]
id: GO:0060493
-name: mesenchymal-endodermal cell signaling involved in lung induction
+name: obsolete mesenchymal-endodermal cell signaling involved in lung induction
namespace: biological_process
-def: "Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud." [GOC:dph, GOC:mtg_lung]
+def: "OBSOLETE. Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud." [GOC:dph, GOC:mtg_lung]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "mesenchymal-endodermal cell signalling involved in lung induction" EXACT [GOC:mah]
-is_a: GO:0060494 ! inductive mesenchymal-endodermal cell signaling
-is_a: GO:0060496 ! mesenchymal-epithelial cell signaling involved in lung development
-is_a: GO:0060497 ! mesenchymal-endodermal cell signaling
-intersection_of: GO:0060497 ! mesenchymal-endodermal cell signaling
-intersection_of: part_of GO:0060492 ! lung induction
-relationship: part_of GO:0060492 ! lung induction
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060492
+consider: GO:0060497
[Term]
id: GO:0060494
@@ -355300,15 +369689,14 @@
[Term]
id: GO:0060504
-name: positive regulation of epithelial cell proliferation involved in lung bud dilation
+name: obsolete positive regulation of epithelial cell proliferation involved in lung bud dilation
namespace: biological_process
-def: "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially." [GOC:dph]
-is_a: GO:0048639 ! positive regulation of developmental growth
-is_a: GO:0060501 ! positive regulation of epithelial cell proliferation involved in lung morphogenesis
-is_a: GO:0061047 ! positive regulation of branching involved in lung morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0060505 ! epithelial cell proliferation involved in lung bud dilation
-relationship: positively_regulates GO:0060505 ! epithelial cell proliferation involved in lung bud dilation
+def: "OBSOLETE. Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially." [GOC:dph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0050679
+consider: GO:0060425
[Term]
id: GO:0060505
@@ -355335,14 +369723,15 @@
[Term]
id: GO:0060507
-name: epidermal growth factor receptor signaling pathway involved in lung development
+name: obsolete epidermal growth factor receptor signaling pathway involved in lung development
namespace: biological_process
-def: "The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development." [GOC:dph, GOC:mtg_lung]
+def: "OBSOLETE. The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development." [GOC:dph, GOC:mtg_lung]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "epidermal growth factor receptor signalling pathway involved in lung development" EXACT [GOC:mah]
-is_a: GO:0007173 ! epidermal growth factor receptor signaling pathway
-intersection_of: GO:0007173 ! epidermal growth factor receptor signaling pathway
-intersection_of: part_of GO:0030324 ! lung development
-relationship: part_of GO:0060495 ! cell-cell signaling involved in lung development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007173
+consider: GO:0030324
[Term]
id: GO:0060508
@@ -355450,21 +369839,23 @@
[Term]
id: GO:0060518
-name: cell migration involved in prostatic bud elongation
+name: obsolete cell migration involved in prostatic bud elongation
namespace: biological_process
-def: "The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud." [GOC:dph, PMID:18977204]
-is_a: GO:0010631 ! epithelial cell migration
-intersection_of: GO:0010631 ! epithelial cell migration
-intersection_of: part_of GO:0060516 ! primary prostatic bud elongation
-relationship: part_of GO:0060516 ! primary prostatic bud elongation
+def: "OBSOLETE. The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud." [GOC:dph, PMID:18977204]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0010631
+consider: GO:0060516
[Term]
id: GO:0060519
-name: cell adhesion involved in prostatic bud elongation
+name: obsolete cell adhesion involved in prostatic bud elongation
namespace: biological_process
-def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud." [GOC:dph, PMID:18977204]
-is_a: GO:0007155 ! cell adhesion
-relationship: part_of GO:0060516 ! primary prostatic bud elongation
+def: "OBSOLETE. The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud." [GOC:dph, PMID:18977204]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0060520
@@ -355480,15 +369871,15 @@
[Term]
id: GO:0060521
-name: mesenchymal-epithelial cell signaling involved in prostate induction
+name: obsolete mesenchymal-epithelial cell signaling involved in prostate induction
namespace: biological_process
-def: "Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate." [GOC:dph, PMID:18977204]
+def: "OBSOLETE. Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate." [GOC:dph, PMID:18977204]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "mesenchymal-epithelial cell signalling involved in prostate induction" EXACT [GOC:mah]
-is_a: GO:0060522 ! inductive mesenchymal to epithelial cell signaling
-is_a: GO:0060739 ! mesenchymal-epithelial cell signaling involved in prostate gland development
-intersection_of: GO:0060638 ! mesenchymal-epithelial cell signaling
-intersection_of: part_of GO:0060514 ! prostate induction
-relationship: part_of GO:0060514 ! prostate induction
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060514
+consider: GO:0060638
[Term]
id: GO:0060522
@@ -355564,25 +369955,25 @@
[Term]
id: GO:0060530
-name: smooth muscle cell differentiation involved in prostate glandular acinus development
+name: obsolete smooth muscle cell differentiation involved in prostate glandular acinus development
namespace: biological_process
-def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus." [GOC:dph, PMID:18977204]
-is_a: GO:0003006 ! developmental process involved in reproduction
-is_a: GO:0051145 ! smooth muscle cell differentiation
-intersection_of: GO:0051145 ! smooth muscle cell differentiation
-intersection_of: part_of GO:0060525 ! prostate glandular acinus development
-relationship: part_of GO:0060525 ! prostate glandular acinus development
+def: "OBSOLETE. The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus." [GOC:dph, PMID:18977204]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0051145
+consider: GO:0060525
[Term]
id: GO:0060531
-name: neuroendocrine cell differentiation involved in prostate gland acinus development
+name: obsolete neuroendocrine cell differentiation involved in prostate gland acinus development
namespace: biological_process
-def: "The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus." [GOC:dph, PMID:18977204]
-is_a: GO:0060742 ! epithelial cell differentiation involved in prostate gland development
-is_a: GO:0061101 ! neuroendocrine cell differentiation
-intersection_of: GO:0061101 ! neuroendocrine cell differentiation
-intersection_of: part_of GO:0060525 ! prostate glandular acinus development
-relationship: part_of GO:0060525 ! prostate glandular acinus development
+def: "OBSOLETE. The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus." [GOC:dph, PMID:18977204]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060525
+consider: GO:0061101
[Term]
id: GO:0060532
@@ -355977,7 +370368,6 @@
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:dph, GOC:tb]
is_a: GO:0032350 ! regulation of hormone metabolic process
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0070613 ! regulation of protein processing
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0016486 ! peptide hormone processing
@@ -355992,7 +370382,6 @@
def: "Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:dph, GOC:tb]
is_a: GO:0010954 ! positive regulation of protein processing
is_a: GO:0032352 ! positive regulation of hormone metabolic process
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0060568 ! regulation of peptide hormone processing
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0016486 ! peptide hormone processing
@@ -356007,7 +370396,6 @@
def: "Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:dph, GOC:tb]
is_a: GO:0010955 ! negative regulation of protein processing
is_a: GO:0032351 ! negative regulation of hormone metabolic process
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0060568 ! regulation of peptide hormone processing
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0016486 ! peptide hormone processing
@@ -356471,14 +370859,15 @@
[Term]
id: GO:0060610
-name: mesenchymal cell differentiation involved in mammary gland development
+name: obsolete mesenchymal cell differentiation involved in mammary gland development
namespace: biological_process
-def: "The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts." [GOC:dph]
+def: "OBSOLETE. The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts." [GOC:dph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "mammary gland mesenchymal cell differentiation" EXACT [GOC:dph]
-is_a: GO:0048762 ! mesenchymal cell differentiation
-intersection_of: GO:0048762 ! mesenchymal cell differentiation
-intersection_of: part_of GO:0030879 ! mammary gland development
-relationship: part_of GO:0030879 ! mammary gland development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0030879
+consider: GO:0048762
created_by: dph
creation_date: 2009-05-15T12:17:06Z
@@ -356575,13 +370964,14 @@
[Term]
id: GO:0060619
-name: cell migration involved in mammary placode formation
+name: obsolete cell migration involved in mammary placode formation
namespace: biological_process
-def: "The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode." [GOC:dph, PMID:12558599]
-is_a: GO:0010631 ! epithelial cell migration
-intersection_of: GO:0016477 ! cell migration
-intersection_of: part_of GO:0060596 ! mammary placode formation
-relationship: part_of GO:0060596 ! mammary placode formation
+def: "OBSOLETE. The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode." [GOC:dph, PMID:12558599]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0016477
+consider: GO:0060596
created_by: dph
creation_date: 2009-05-18T09:41:49Z
@@ -356854,13 +371244,14 @@
[Term]
id: GO:0060642
-name: white fat cell differentiation involved in mammary gland fat development
+name: obsolete white fat cell differentiation involved in mammary gland fat development
namespace: biological_process
-def: "The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole." [GOC:dph, PMID:12558599]
-is_a: GO:0050872 ! white fat cell differentiation
-intersection_of: GO:0050872 ! white fat cell differentiation
-intersection_of: part_of GO:0060611 ! mammary gland fat development
-relationship: part_of GO:0060611 ! mammary gland fat development
+def: "OBSOLETE. The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole." [GOC:dph, PMID:12558599]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0050872
+consider: GO:0060611
created_by: dph
creation_date: 2009-05-27T05:50:56Z
@@ -356906,13 +371297,14 @@
[Term]
id: GO:0060647
-name: mesenchymal cell condensation involved in mammary fat development
+name: obsolete mesenchymal cell condensation involved in mammary fat development
namespace: biological_process
-def: "The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development." [GOC:dph, PMID:12558599]
-is_a: GO:0098609 ! cell-cell adhesion
-intersection_of: GO:0098609 ! cell-cell adhesion
-intersection_of: part_of GO:0060611 ! mammary gland fat development
-relationship: part_of GO:0060611 ! mammary gland fat development
+def: "OBSOLETE. The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development." [GOC:dph, PMID:12558599]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060611
+consider: GO:0098609
created_by: dph
creation_date: 2009-05-29T08:33:29Z
@@ -356950,14 +371342,14 @@
[Term]
id: GO:0060651
-name: regulation of epithelial cell proliferation involved in mammary gland bud elongation
+name: obsolete regulation of epithelial cell proliferation involved in mammary gland bud elongation
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud." [GOC:dph, PMID:12558599]
-is_a: GO:0033599 ! regulation of mammary gland epithelial cell proliferation
-is_a: GO:2000027 ! regulation of animal organ morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0060650 ! epithelial cell proliferation involved in mammary gland bud elongation
-relationship: regulates GO:0060650 ! epithelial cell proliferation involved in mammary gland bud elongation
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud." [GOC:dph, PMID:12558599]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060650
+consider: GO:0065007
created_by: dph
creation_date: 2009-05-29T08:57:18Z
@@ -356974,14 +371366,15 @@
[Term]
id: GO:0060653
-name: epithelial cell differentiation involved in mammary gland cord morphogenesis
+name: obsolete epithelial cell differentiation involved in mammary gland cord morphogenesis
namespace: biological_process
-def: "The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified." [GOC:dph, PMID:12558599]
+def: "OBSOLETE. The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified." [GOC:dph, PMID:12558599]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "epithelial cell differentiation involved in mammary gland sprout morphogenesis" RELATED [GOC:dph]
-is_a: GO:0060644 ! mammary gland epithelial cell differentiation
-intersection_of: GO:0030855 ! epithelial cell differentiation
-intersection_of: part_of GO:0060652 ! mammary gland cord morphogenesis
-relationship: part_of GO:0060652 ! mammary gland cord morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0030855
+consider: GO:0060652
created_by: dph
creation_date: 2009-05-29T09:17:16Z
@@ -357009,13 +371402,13 @@
[Term]
id: GO:0060656
-name: regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling
+name: obsolete regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling
namespace: biological_process
-def: "Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell." [GOC:dph, PMID:12558599]
+def: "OBSOLETE. Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell." [GOC:dph, PMID:12558599]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signalling" EXACT [GOC:mah]
-is_a: GO:0007267 ! cell-cell signaling
-is_a: GO:0060762 ! regulation of branching involved in mammary gland duct morphogenesis
-relationship: regulates GO:0060655 ! branching involved in mammary gland cord morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2009-05-29T09:34:31Z
@@ -357054,13 +371447,14 @@
[Term]
id: GO:0060660
-name: epidermis morphogenesis involved in nipple formation
+name: obsolete epidermis morphogenesis involved in nipple formation
namespace: biological_process
-def: "The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection." [GOC:dph, PMID:12558599]
-is_a: GO:0048730 ! epidermis morphogenesis
-intersection_of: GO:0048730 ! epidermis morphogenesis
-intersection_of: part_of GO:0060658 ! nipple morphogenesis
-relationship: part_of GO:0060658 ! nipple morphogenesis
+def: "OBSOLETE. The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection." [GOC:dph, PMID:12558599]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0048730
+consider: GO:0060658
created_by: dph
creation_date: 2009-05-29T11:04:04Z
@@ -357087,15 +371481,16 @@
[Term]
id: GO:0060663
-name: apoptotic process involved in salivary gland cavitation
+name: obsolete apoptotic process involved in salivary gland cavitation
namespace: biological_process
-def: "Any apoptotic process in which the solid core of the gland is hollowed out to form the duct." [GOC:dph, GOC:mtg_apoptosis, PMID:17336109]
+def: "OBSOLETE. Any apoptotic process in which the solid core of the gland is hollowed out to form the duct." [GOC:dph, GOC:mtg_apoptosis, PMID:17336109]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "apoptosis involved in salivary gland cavitation" NARROW []
-is_a: GO:0060609 ! apoptotic process involved in tube lumen cavitation
-intersection_of: GO:0006915 ! apoptotic process
-intersection_of: part_of GO:0060662 ! salivary gland cavitation
-relationship: part_of GO:0060662 ! salivary gland cavitation
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24751" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0006915
+consider: GO:0060662
created_by: dph
creation_date: 2009-06-01T08:27:16Z
@@ -357207,14 +371602,15 @@
[Term]
id: GO:0060673
-name: cell-cell signaling involved in placenta development
+name: obsolete cell-cell signaling involved in placenta development
namespace: biological_process
-def: "Any process that mediates the transfer of information from one cell to another." [GOC:dph, PMID:16916377]
+def: "OBSOLETE. Any process that mediates the transfer of information from one cell to another." [GOC:dph, PMID:16916377]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "cell-cell signalling involved in placenta development" EXACT [GOC:mah]
-is_a: GO:0007267 ! cell-cell signaling
-intersection_of: GO:0007267 ! cell-cell signaling
-intersection_of: part_of GO:0001890 ! placenta development
-relationship: part_of GO:0001892 ! embryonic placenta development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001890
+consider: GO:0007267
created_by: dph
creation_date: 2009-06-02T12:58:03Z
@@ -357284,13 +371680,14 @@
[Term]
id: GO:0060680
-name: lateral sprouting involved in ureteric bud morphogenesis
+name: obsolete lateral sprouting involved in ureteric bud morphogenesis
namespace: biological_process
-def: "The process in which a branch forms along the side of a ureteric bud." [GOC:dph, PMID:16916378]
-is_a: GO:0060601 ! lateral sprouting from an epithelium
-intersection_of: GO:0060601 ! lateral sprouting from an epithelium
-intersection_of: part_of GO:0001658 ! branching involved in ureteric bud morphogenesis
-relationship: part_of GO:0001658 ! branching involved in ureteric bud morphogenesis
+def: "OBSOLETE. The process in which a branch forms along the side of a ureteric bud." [GOC:dph, PMID:16916378]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001658
+consider: GO:0060601
created_by: dph
creation_date: 2009-06-02T02:44:27Z
@@ -357432,13 +371829,14 @@
[Term]
id: GO:0060692
-name: mesenchymal cell differentiation involved in salivary gland development
+name: obsolete mesenchymal cell differentiation involved in salivary gland development
namespace: biological_process
-def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph]
-is_a: GO:0048762 ! mesenchymal cell differentiation
-is_a: GO:0060689 ! cell differentiation involved in salivary gland development
-intersection_of: GO:0048762 ! mesenchymal cell differentiation
-intersection_of: part_of GO:0007431 ! salivary gland development
+def: "OBSOLETE. The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007431
+consider: GO:0048762
created_by: dph
creation_date: 2009-06-08T01:08:44Z
@@ -357580,25 +371978,27 @@
[Term]
id: GO:0060704
-name: acinar cell differentiation involved in salivary gland development
+name: obsolete acinar cell differentiation involved in salivary gland development
namespace: biological_process
-def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland." [GOC:dph, GOC:tb]
-is_a: GO:0060690 ! epithelial cell differentiation involved in salivary gland development
-is_a: GO:0090425 ! acinar cell differentiation
-intersection_of: GO:0090425 ! acinar cell differentiation
-intersection_of: part_of GO:0007431 ! salivary gland development
+def: "OBSOLETE. The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland." [GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007431
+consider: GO:0090425
created_by: dph
creation_date: 2009-06-09T09:32:46Z
[Term]
id: GO:0060705
-name: neuron differentiation involved in salivary gland development
+name: obsolete neuron differentiation involved in salivary gland development
namespace: biological_process
-def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland." [GOC:dph]
-is_a: GO:0030182 ! neuron differentiation
-is_a: GO:0060689 ! cell differentiation involved in salivary gland development
-intersection_of: GO:0030182 ! neuron differentiation
-intersection_of: part_of GO:0007431 ! salivary gland development
+def: "OBSOLETE. The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland." [GOC:dph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007431
+consider: GO:0030182
created_by: dph
creation_date: 2009-06-09T09:35:52Z
@@ -358778,14 +373178,14 @@
[Term]
id: GO:0060808
-name: positive regulation of mesodermal to mesenchymal transition involved in gastrulation
+name: obsolete positive regulation of mesodermal to mesenchymal transition involved in gastrulation
namespace: biological_process
-def: "Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb]
-is_a: GO:0010718 ! positive regulation of epithelial to mesenchymal transition
-is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0060809 ! mesodermal to mesenchymal transition involved in gastrulation
-relationship: positively_regulates GO:0060809 ! mesodermal to mesenchymal transition involved in gastrulation
+def: "OBSOLETE. Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007369
+consider: GO:0010718
created_by: dph
creation_date: 2009-08-06T02:32:53Z
@@ -358858,13 +373258,14 @@
[Term]
id: GO:0060815
-name: regulation of translation involved in anterior/posterior axis specification
+name: obsolete regulation of translation involved in anterior/posterior axis specification
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb]
-is_a: GO:0006417 ! regulation of translation
-intersection_of: GO:0006417 ! regulation of translation
-intersection_of: part_of GO:0009948 ! anterior/posterior axis specification
-relationship: part_of GO:0009948 ! anterior/posterior axis specification
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0006417
+consider: GO:0009948
created_by: dph
creation_date: 2009-08-07T10:02:31Z
@@ -359071,15 +373472,16 @@
[Term]
id: GO:0060830
-name: ciliary receptor clustering involved in smoothened signaling pathway
+name: obsolete ciliary receptor clustering involved in smoothened signaling pathway
namespace: biological_process
-def: "Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway." [GOC:cilia, GOC:dph, GOC:sdb_2009, GOC:tb]
+def: "OBSOLETE. Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway." [GOC:cilia, GOC:dph, GOC:sdb_2009, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "ciliary receptor clustering involved in hedgehog signaling pathway" EXACT [GOC:bf, GOC:ecd]
synonym: "ciliary receptor clustering involved in hh signaling pathway" EXACT [GOC:bf, GOC:ecd]
synonym: "ciliary receptor clustering involved in smoothened signalling pathway" EXACT [GOC:mah]
-is_a: GO:0043113 ! receptor clustering
-relationship: occurs_in GO:0005929 ! cilium
-relationship: part_of GO:0007224 ! smoothened signaling pathway
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0043113
created_by: dph
creation_date: 2009-08-11T02:06:33Z
@@ -359299,14 +373701,15 @@
[Term]
id: GO:0060851
-name: vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment
+name: obsolete vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment
namespace: biological_process
-def: "The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate." [GOC:dph, GOC:sdb_2009, GOC:tb]
+def: "OBSOLETE. The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate." [GOC:dph, GOC:sdb_2009, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "vascular endothelial growth factor receptor signalling pathway involved in lymphatic endothelial cell fate commitment" EXACT [GOC:mah]
-is_a: GO:0048010 ! vascular endothelial growth factor receptor signaling pathway
-intersection_of: GO:0048010 ! vascular endothelial growth factor receptor signaling pathway
-intersection_of: part_of GO:0060838 ! lymphatic endothelial cell fate commitment
-relationship: part_of GO:0060838 ! lymphatic endothelial cell fate commitment
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0048010
+consider: GO:0060838
created_by: dph
creation_date: 2009-08-12T11:45:19Z
@@ -359528,13 +373931,14 @@
[Term]
id: GO:0060870
-name: cell wall disassembly involved in floral organ abscission
+name: obsolete cell wall disassembly involved in floral organ abscission
namespace: biological_process
-def: "A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:tb]
-is_a: GO:0009830 ! cell wall modification involved in abscission
-intersection_of: GO:0044277 ! cell wall disassembly
-intersection_of: part_of GO:0010227 ! floral organ abscission
-relationship: part_of GO:0010227 ! floral organ abscission
+def: "OBSOLETE. A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0010227
+consider: GO:0044277
created_by: dph
creation_date: 2009-08-12T07:15:36Z
@@ -359622,27 +374026,28 @@
[Term]
id: GO:0060880
-name: cell morphogenesis involved in semicircular canal fusion
+name: obsolete cell morphogenesis involved in semicircular canal fusion
namespace: biological_process
-def: "The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion." [GOC:dph, GOC:sdb_2009, GOC:tb]
-is_a: GO:0000902 ! cell morphogenesis
-is_a: GO:0048598 ! embryonic morphogenesis
-intersection_of: GO:0000902 ! cell morphogenesis
-intersection_of: part_of GO:0060879 ! semicircular canal fusion
-relationship: part_of GO:0060879 ! semicircular canal fusion
+def: "OBSOLETE. The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion." [GOC:dph, GOC:sdb_2009, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0000902
+consider: GO:0060879
created_by: dph
creation_date: 2009-08-13T10:13:25Z
[Term]
id: GO:0060882
-name: basement membrane disassembly involved in semicircular canal fusion
+name: obsolete basement membrane disassembly involved in semicircular canal fusion
namespace: biological_process
-def: "A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion." [GOC:dph, GOC:sdb_2009, GOC:tb]
+def: "OBSOLETE. A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion." [GOC:dph, GOC:sdb_2009, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "basal lamina disassembly involved in semicircular canal fusion" RELATED []
-is_a: GO:0034769 ! basement membrane disassembly
-intersection_of: GO:0034769 ! basement membrane disassembly
-intersection_of: part_of GO:0060879 ! semicircular canal fusion
-relationship: part_of GO:0060879 ! semicircular canal fusion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0034769
+consider: GO:0060879
created_by: dph
creation_date: 2009-08-13T11:29:52Z
@@ -359970,11 +374375,12 @@
[Term]
id: GO:0060910
-name: negative regulation of DNA replication initiation involved in plasmid copy number maintenance
+name: obsolete negative regulation of DNA replication initiation involved in plasmid copy number maintenance
namespace: biological_process
-def: "Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance." [GOC:dph, GOC:tb]
-is_a: GO:0032297 ! negative regulation of DNA-templated DNA replication initiation
-is_a: GO:0060909 ! regulation of DNA replication initiation involved in plasmid copy number maintenance
+def: "OBSOLETE. Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance." [GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2009-09-04T02:56:29Z
@@ -360534,7 +374940,7 @@
namespace: molecular_function
def: "Binds to and stops, prevents or reduces the activity of phospholipase D." [GOC:dph, GOC:tb]
is_a: GO:0004859 ! phospholipase inhibitor activity
-relationship: negatively_regulates GO:0004630 ! phospholipase D activity
+relationship: negatively_regulates GO:0004630 ! D-type glycerophospholipase activity
created_by: dph
creation_date: 2009-10-05T02:47:26Z
@@ -362201,6 +376607,7 @@
is_a: GO:0002085 ! inhibition of neuroepithelial cell differentiation
is_a: GO:0045665 ! negative regulation of neuron differentiation
is_a: GO:0061105 ! regulation of stomach neuroendocrine cell differentiation
+is_a: GO:7770019 ! negative regulation of enteroendocrine cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0061102 ! stomach neuroendocrine cell differentiation
relationship: negatively_regulates GO:0061102 ! stomach neuroendocrine cell differentiation
@@ -362250,27 +376657,27 @@
[Term]
id: GO:0061111
-name: epithelial-mesenchymal cell signaling involved in lung development
+name: obsolete epithelial-mesenchymal cell signaling involved in lung development
namespace: biological_process
-def: "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ." [GOC:dph]
+def: "OBSOLETE. Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ." [GOC:dph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "epithelial-mesenchymal cell signalling involved in lung development" EXACT [GOC:mah]
-is_a: GO:0060495 ! cell-cell signaling involved in lung development
-is_a: GO:0060684 ! epithelial-mesenchymal cell signaling
-intersection_of: GO:0060684 ! epithelial-mesenchymal cell signaling
-intersection_of: part_of GO:0030324 ! lung development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0030324
+consider: GO:0060684
created_by: dph
creation_date: 2010-05-05T11:14:38Z
[Term]
id: GO:0061112
-name: negative regulation of bud outgrowth involved in lung branching
+name: obsolete negative regulation of bud outgrowth involved in lung branching
namespace: biological_process
-def: "Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching." [GOC:dph]
-is_a: GO:0048640 ! negative regulation of developmental growth
-is_a: GO:0061048 ! negative regulation of branching involved in lung morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0060447 ! bud outgrowth involved in lung branching
-relationship: negatively_regulates GO:0060447 ! bud outgrowth involved in lung branching
+def: "OBSOLETE. Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching." [GOC:dph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060447
created_by: dph
creation_date: 2010-05-05T11:20:42Z
@@ -362520,7 +376927,6 @@
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome." [GOC:dph, GOC:tb]
is_a: GO:0042176 ! regulation of protein catabolic process
-is_a: GO:1903050 ! regulation of proteolysis involved in protein catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010498 ! proteasomal protein catabolic process
relationship: regulates GO:0010498 ! proteasomal protein catabolic process
@@ -362578,11 +376984,13 @@
[Term]
id: GO:0061142
-name: mesothelial-mesenchymal cell signaling involved in early lung development
+name: obsolete mesothelial-mesenchymal cell signaling involved in early lung development
namespace: biological_process
-def: "Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung." [GOC:dph]
+def: "OBSOLETE. Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung." [GOC:dph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "mesothelial-mesenchymal cell signalling involved in early lung development" EXACT [GOC:mah]
-is_a: GO:0060495 ! cell-cell signaling involved in lung development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2010-05-25T09:35:32Z
@@ -363331,14 +377739,15 @@
[Term]
id: GO:0061210
-name: cell-cell signaling involved in mesonephros development
+name: obsolete cell-cell signaling involved in mesonephros development
namespace: biological_process
-def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10]
+def: "OBSOLETE. Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "cell-cell signalling involved in mesonephros development" EXACT [GOC:mah]
-is_a: GO:0060995 ! cell-cell signaling involved in kidney development
-intersection_of: GO:0007267 ! cell-cell signaling
-intersection_of: part_of GO:0001823 ! mesonephros development
-relationship: part_of GO:0001823 ! mesonephros development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001823
+consider: GO:0007267
created_by: dph
creation_date: 2010-08-17T03:24:08Z
@@ -363464,12 +377873,12 @@
[Term]
id: GO:0061222
-name: mesonephric mesenchymal cell proliferation involved in mesonephros development
+name: obsolete mesonephric mesenchymal cell proliferation involved in mesonephros development
namespace: biological_process
-def: "The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population." [GOC:mtg_kidney_jan10]
-is_a: GO:0061209 ! cell proliferation involved in mesonephros development
-is_a: GO:0072135 ! kidney mesenchymal cell proliferation
-relationship: part_of GO:0061219 ! mesonephric mesenchyme development
+def: "OBSOLETE. The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2010-08-19T01:20:14Z
@@ -363496,14 +377905,14 @@
[Term]
id: GO:0061225
-name: mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development
+name: obsolete mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development
namespace: biological_process
-def: "The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa." [GOC:mtg_kidney_jan10]
+def: "OBSOLETE. The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "mesonephric Goormaghtigh proliferation" RELATED [GOC:mtg_kidney_jan10]
synonym: "mesonephric lacis cell proliferation" RELATED [GOC:mtg_kidney_jan10]
-is_a: GO:0061209 ! cell proliferation involved in mesonephros development
-is_a: GO:0072122 ! extraglomerular mesangial cell proliferation
-relationship: part_of GO:0061215 ! mesonephric nephron development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2010-08-19T01:34:59Z
@@ -363639,25 +378048,26 @@
[Term]
id: GO:0061238
-name: establishment of planar polarity involved in mesonephric nephron morphogenesis
+name: obsolete establishment of planar polarity involved in mesonephric nephron morphogenesis
namespace: biological_process
-def: "Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros." [GOC:mtg_kidney_jan10]
+def: "OBSOLETE. Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "establishment of planar cell polarity involved in mesonephric nephron morphogenesis" NARROW [GOC:mtg_kidney_jan10]
-is_a: GO:0072046 ! establishment of planar polarity involved in nephron morphogenesis
-intersection_of: GO:0001736 ! establishment of planar polarity
-intersection_of: part_of GO:0061228 ! mesonephric nephron morphogenesis
-relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001736
+consider: GO:0061228
created_by: dph
creation_date: 2010-08-19T03:04:40Z
[Term]
id: GO:0061239
-name: mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis
+name: obsolete mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis
namespace: biological_process
-def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10]
-is_a: GO:0061208 ! cell differentiation involved in mesonephros development
-is_a: GO:0072037 ! mesenchymal stem cell differentiation involved in nephron morphogenesis
-relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis
+def: "OBSOLETE. The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2010-08-19T03:06:46Z
@@ -363998,14 +378408,14 @@
[Term]
id: GO:0061271
-name: mesenchymal to epithelial transition involved in mesonephric renal vesicle formation
+name: obsolete mesenchymal to epithelial transition involved in mesonephric renal vesicle formation
namespace: biological_process
-def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle." [GOC:mtg_kidney_jan10]
-is_a: GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
-is_a: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation
-intersection_of: GO:0060231 ! mesenchymal to epithelial transition
-intersection_of: part_of GO:0061262 ! mesonephric renal vesicle formation
-relationship: part_of GO:0061262 ! mesonephric renal vesicle formation
+def: "OBSOLETE. A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060231
+consider: GO:0061262
created_by: dph
creation_date: 2010-08-30T03:26:30Z
@@ -364087,27 +378497,27 @@
[Term]
id: GO:0061279
-name: epithelial cell migration involved in mesonephric distal tubule morphogenesis
+name: obsolete epithelial cell migration involved in mesonephric distal tubule morphogenesis
namespace: biological_process
-def: "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis." [GOC:mtg_kidney_jan10]
-is_a: GO:0061278 ! epithelial cell migration involved in mesonephric nephron tubule morphogenesis
-is_a: GO:0072157 ! epithelial cell migration involved in distal tubule morphogenesis
-intersection_of: GO:0010631 ! epithelial cell migration
-intersection_of: part_of GO:0061273 ! mesonephric distal tubule morphogenesis
-relationship: part_of GO:0061273 ! mesonephric distal tubule morphogenesis
+def: "OBSOLETE. The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0010631
+consider: GO:0061273
created_by: dph
creation_date: 2010-09-02T01:20:56Z
[Term]
id: GO:0061280
-name: epithelial cell migration involved in mesonephric proximal tubule morphogenesis
+name: obsolete epithelial cell migration involved in mesonephric proximal tubule morphogenesis
namespace: biological_process
-def: "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis." [GOC:mtg_kidney_jan10]
-is_a: GO:0061278 ! epithelial cell migration involved in mesonephric nephron tubule morphogenesis
-is_a: GO:0072159 ! epithelial cell migration involved in proximal tubule morphogenesis
-intersection_of: GO:0010631 ! epithelial cell migration
-intersection_of: part_of GO:0061276 ! mesonephric proximal tubule morphogenesis
-relationship: part_of GO:0061276 ! mesonephric proximal tubule morphogenesis
+def: "OBSOLETE. The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0010631
+consider: GO:0061276
created_by: dph
creation_date: 2010-09-02T01:23:43Z
@@ -364289,50 +378699,39 @@
[Term]
id: GO:0061295
-name: regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
+name: obsolete regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
namespace: biological_process
-def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
+def: "OBSOLETE. Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
synonym: "regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW []
synonym: "regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT []
-is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
-relationship: regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis
-relationship: regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2010-09-06T09:48:56Z
[Term]
id: GO:0061296
-name: negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
+name: obsolete negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
namespace: biological_process
-def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
+def: "OBSOLETE. Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
synonym: "negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW []
synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT []
-is_a: GO:0061218 ! negative regulation of mesonephros development
-is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
-is_a: GO:0072040 ! negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
-relationship: negatively_regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis
-relationship: negatively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0001822
created_by: dph
creation_date: 2010-09-06T09:54:49Z
[Term]
id: GO:0061297
-name: positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
+name: obsolete positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
namespace: biological_process
-def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
+def: "OBSOLETE. Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW []
synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT []
-is_a: GO:0061213 ! positive regulation of mesonephros development
-is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
-is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
-relationship: positively_regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis
-relationship: positively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2010-09-06T09:58:59Z
@@ -364511,14 +378910,15 @@
[Term]
id: GO:0061313
-name: fibroblast growth factor receptor signaling pathway involved in heart development
+name: obsolete fibroblast growth factor receptor signaling pathway involved in heart development
namespace: biological_process
-def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time." [GOC:mtg_heart]
+def: "OBSOLETE. The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time." [GOC:mtg_heart]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "fibroblast growth factor receptor signalling pathway involved in heart development" EXACT [GOC:mah]
-is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway
-is_a: GO:0061311 ! cell surface receptor signaling pathway involved in heart development
-intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway
-intersection_of: part_of GO:0007507 ! heart development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007507
+consider: GO:0008543
created_by: dph
creation_date: 2010-09-24T08:15:08Z
@@ -364771,14 +379171,14 @@
[Term]
id: GO:0061335
-name: cell growth involved in Malpighian tubule morphogenesis
+name: obsolete cell growth involved in Malpighian tubule morphogenesis
namespace: biological_process
-def: "The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]
-is_a: GO:0048588 ! developmental cell growth
-is_a: GO:0060560 ! developmental growth involved in morphogenesis
-intersection_of: GO:0048588 ! developmental cell growth
-intersection_of: part_of GO:0007443 ! Malpighian tubule morphogenesis
-relationship: part_of GO:0007443 ! Malpighian tubule morphogenesis
+def: "OBSOLETE. The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007443
+consider: GO:0048588
created_by: dph
creation_date: 2010-09-28T02:08:25Z
@@ -364891,11 +379291,12 @@
[Term]
id: GO:0061345
-name: planar cell polarity pathway involved in cardiac muscle cell fate commitment
+name: obsolete planar cell polarity pathway involved in cardiac muscle cell fate commitment
namespace: biological_process
-def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate." [GOC:dph, GOC:mtg_heart, PMID:16860783]
-is_a: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway
-is_a: GO:0061341 ! non-canonical Wnt signaling pathway involved in heart development
+def: "OBSOLETE. The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate." [GOC:dph, GOC:mtg_heart, PMID:16860783]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2010-09-30T12:39:05Z
@@ -365104,14 +379505,13 @@
[Term]
id: GO:0061363
-name: negative regulation of progesterone biosynthesis involved in luteolysis
+name: obsolete negative regulation of progesterone biosynthesis involved in luteolysis
namespace: biological_process
-def: "Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis." [GOC:dph]
+def: "OBSOLETE. Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis." [GOC:dph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM.
synonym: "functional luteolysis" EXACT [GOC:dph]
-is_a: GO:2000183 ! negative regulation of progesterone biosynthetic process
-intersection_of: GO:2000183 ! negative regulation of progesterone biosynthetic process
-intersection_of: part_of GO:0001554 ! luteolysis
-relationship: part_of GO:0001554 ! luteolysis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31228" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2010-10-14T03:08:41Z
@@ -365336,13 +379736,14 @@
[Term]
id: GO:0061385
-name: fibroblast proliferation involved in heart morphogenesis
+name: obsolete fibroblast proliferation involved in heart morphogenesis
namespace: biological_process
-def: "The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart." [GOC:dph]
-is_a: GO:0048144 ! fibroblast proliferation
-is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis
-intersection_of: GO:0048144 ! fibroblast proliferation
-intersection_of: part_of GO:0003007 ! heart morphogenesis
+def: "OBSOLETE. The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart." [GOC:dph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003007
+consider: GO:0048144
created_by: dph
creation_date: 2011-02-10T01:41:59Z
@@ -366144,20 +380545,23 @@
[Term]
id: GO:0061456
-name: mesenchymal stem cell migration involved in uteric bud morphogenesis
+name: obsolete mesenchymal stem cell migration involved in uteric bud morphogenesis
namespace: biological_process
-def: "The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:dph, GOC:tb]
-is_a: GO:0035787 ! cell migration involved in kidney development
-relationship: part_of GO:0060675 ! ureteric bud morphogenesis
+def: "OBSOLETE. The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2012-08-22T17:19:22Z
[Term]
id: GO:0061457
-name: mesonephric cell migration involved in male gonad development
+name: obsolete mesonephric cell migration involved in male gonad development
namespace: biological_process
-def: "The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development." [GOC:dph, GOC:tb]
-is_a: GO:0016477 ! cell migration
+def: "OBSOLETE. The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development." [GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2012-08-22T17:31:00Z
@@ -366213,8 +380617,13 @@
namespace: molecular_function
def: "Catalysis of the reaction O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate. Removes the acetyl group from either the 2'' or 3'' position of O-acetyl-ADP-ribose." [EC:3.1.1.106]
xref: EC:3.1.1.106
+xref: RHEA:57060
+xref: RHEA:59244
is_a: GO:0019213 ! deacetylase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.106
+property_value: skos:narrowMatch RHEA:57060
+property_value: skos:narrowMatch RHEA:59244
created_by: dph
creation_date: 2012-10-05T11:05:06Z
@@ -366308,6 +380717,7 @@
def: "Catalysis of the reaction: L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate (murein tripeptide) + H2O = L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate." [PMID:22970852, RHEA:28398]
xref: RHEA:28398
is_a: GO:0004181 ! metallocarboxypeptidase activity
+property_value: skos:exactMatch RHEA:28398
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16802" xsd:anyURI
created_by: dph
creation_date: 2012-11-06T12:23:39Z
@@ -366526,7 +380936,10 @@
xref: Reactome:R-HSA-3244614 "cGAS produces cyclic GMP-AMP"
xref: RHEA:42064
is_a: GO:0140699 ! cyclic GMP-AMP synthase activity
+property_value: skos:exactMatch EC:2.7.7.86
+property_value: skos:exactMatch RHEA:42064
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21980" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2013-01-04T07:17:57Z
@@ -366543,7 +380956,7 @@
[Term]
id: GO:0061503
-name: tRNA threonylcarbamoyladenosine dehydratase
+name: tRNA threonylcarbamoyladenosine dehydratase activity
namespace: molecular_function
def: "Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A." [GOC:dph, PMID:23242255]
is_a: GO:0016836 ! hydro-lyase activity
@@ -366658,7 +381071,9 @@
xref: RHEA:71535
is_a: GO:0015152 ! glucose-6-phosphate transmembrane transporter activity
is_a: GO:0015526 ! hexose-phosphate:phosphate antiporter activity
+property_value: skos:exactMatch RHEA:71535
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2013-04-17T08:47:40Z
@@ -366745,7 +381160,10 @@
xref: EC:3.1.2.28
xref: RHEA:26309
is_a: GO:0016289 ! acyl-CoA hydrolase activity
+property_value: skos:exactMatch EC:3.1.2.28
+property_value: skos:exactMatch RHEA:26309
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26441" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2013-04-18T14:37:32Z
@@ -366927,10 +381345,8 @@
name: octopamine secretion
namespace: biological_process
def: "The controlled release of octopamine by a cell." [GOC:dph]
-is_a: GO:0015695 ! organic cation transport
-is_a: GO:0015850 ! organic hydroxy compound transport
is_a: GO:0032940 ! secretion by cell
-is_a: GO:0071705 ! nitrogen compound transport
+is_a: GO:7770033 ! octopamine transport
created_by: dph
creation_date: 2013-06-21T16:24:02Z
@@ -366973,8 +381389,11 @@
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
relationship: part_of GO:0006744 ! ubiquinone biosynthetic process
+property_value: skos:exactMatch EC:2.1.1.64
+property_value: skos:exactMatch RHEA:44380
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25680" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29420" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2013-06-25T08:01:46Z
@@ -367005,9 +381424,8 @@
name: tyramine secretion
namespace: biological_process
def: "The regulated release of a tyramine by a cell." [GOC:dph]
-is_a: GO:0015844 ! monoamine transport
-is_a: GO:0015850 ! organic hydroxy compound transport
is_a: GO:0061531 ! primary amine secretion
+is_a: GO:7770032 ! tyramine transport
created_by: dph
creation_date: 2013-06-25T09:14:07Z
@@ -367388,6 +381806,9 @@
xref: EC:2.3.1.184
xref: RHEA:10096
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.184
+property_value: skos:exactMatch RHEA:10096
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
created_by: dph
creation_date: 2013-11-15T19:48:23Z
@@ -367520,11 +381941,12 @@
[Term]
id: GO:0061592
-name: phosphatidylserine exposure on osteoblast involved in bone mineralization
+name: obsolete phosphatidylserine exposure on osteoblast involved in bone mineralization
namespace: biological_process
-def: "A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization." [GOC:krc, PMID:22936354]
-is_a: GO:0017121 ! plasma membrane phospholipid scrambling
-relationship: part_of GO:0030282 ! bone mineralization
+def: "OBSOLETE. A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization." [GOC:krc, PMID:22936354]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2014-02-05T15:27:39Z
@@ -367536,6 +381958,8 @@
xref: EC:5.3.1.31
xref: RHEA:40439
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.31
+property_value: skos:exactMatch RHEA:40439
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29695" xsd:anyURI
created_by: dph
creation_date: 2014-02-10T09:56:04Z
@@ -367549,6 +381973,9 @@
xref: MetaCyc:RXN-15297
xref: RHEA:40443
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.184
+property_value: skos:exactMatch RHEA:40443
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2014-02-10T09:59:26Z
@@ -367570,6 +381997,9 @@
xref: MetaCyc:RXN-15299
xref: RHEA:40511
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.373
+property_value: skos:exactMatch RHEA:40511
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2014-02-10T10:09:43Z
@@ -367591,6 +382021,9 @@
xref: EC:2.7.7.75
xref: RHEA:31331
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.75
+property_value: skos:exactMatch RHEA:31331
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2014-02-10T14:14:06Z
@@ -367603,6 +382036,9 @@
xref: Reactome:R-HSA-947531 "Molybdenum ion transfer onto molybdopterin"
xref: RHEA:35047
is_a: GO:0016740 ! transferase activity
+property_value: skos:exactMatch EC:2.10.1.1
+property_value: skos:exactMatch RHEA:35047
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2014-02-10T14:30:31Z
@@ -367614,6 +382050,9 @@
xref: EC:2.7.7.76
xref: RHEA:31335
is_a: GO:0070567 ! cytidylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.76
+property_value: skos:exactMatch RHEA:31335
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2014-02-10T14:46:38Z
@@ -367625,6 +382064,9 @@
xref: EC:2.7.7.77
xref: RHEA:34243
is_a: GO:0070568 ! guanylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.77
+property_value: skos:exactMatch RHEA:34243
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2014-02-10T14:54:36Z
@@ -367636,6 +382078,9 @@
xref: EC:2.8.1.11
xref: RHEA:48612
is_a: GO:0016783 ! sulfurtransferase activity
+property_value: skos:exactMatch EC:2.8.1.11
+property_value: skos:exactMatch RHEA:48612
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2014-02-11T11:56:16Z
@@ -367647,6 +382092,9 @@
xref: EC:2.7.7.80
xref: RHEA:43616
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.80
+property_value: skos:exactMatch RHEA:43616
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2014-02-11T12:01:32Z
@@ -367678,7 +382126,6 @@
namespace: molecular_function
def: "Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein." [GOC:dph, GOC:pg, GOC:vw, PMID:28713609, Wikipedia:Nuclear_transport]
synonym: "importin activity" RELATED []
-xref: Reactome:R-HSA-2065550 "SREBP1A,1C,2 binds Importin beta-1"
is_a: GO:0140142 ! nucleocytoplasmic carrier activity
intersection_of: GO:0140142 ! nucleocytoplasmic carrier activity
intersection_of: part_of GO:0051170 ! import into nucleus
@@ -367697,22 +382144,24 @@
xref: Reactome:R-HSA-70342 "ALDOB tetramer cleaves Fru-1-P to GA and DHAP"
xref: RHEA:30851
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch RHEA:30851
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27617" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2014-03-28T08:54:24Z
[Term]
id: GO:0061610
-name: glycerol to glycerone phosphate metabolic process
+name: glycerol catabolic process to glycerone phosphate
namespace: biological_process
-def: "The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate." [GOC:dph, ISBN:0201090910]
+def: "The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate." [PMID:30930107]
synonym: "glycerol metabolism to DHAP" EXACT [GOC:dph]
synonym: "glycerol metabolism to dihydroxyacetone phosphate" EXACT [GOC:dph]
synonym: "glycerol metabolism to glycerone phosphate" EXACT [GOC:dph]
synonym: "glycerol to DHAP metabolic process" EXACT [GOC:dph]
synonym: "glycerol to dihydroxyacetone phosphate metabolic process" EXACT [GOC:dph]
-is_a: GO:0006071 ! glycerol metabolic process
is_a: GO:0006796 ! phosphate-containing compound metabolic process
+is_a: GO:0019563 ! glycerol catabolic process
is_a: GO:0019637 ! organophosphate metabolic process
is_a: GO:0034308 ! primary alcohol metabolic process
is_a: GO:0042180 ! ketone metabolic process
@@ -367720,6 +382169,7 @@
relationship: has_part GO:0004370 ! glycerol kinase activity
relationship: has_part GO:0141152 ! glycerol-3-phosphate dehydrogenase (NAD+) activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26974" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31218" xsd:anyURI
created_by: dph
creation_date: 2014-04-03T13:26:21Z
@@ -367729,10 +382179,14 @@
namespace: biological_process
def: "The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate." [GOC:dph, ISBN:0201090910, ISBN:0879010479]
synonym: "mannose metabolism to fructose-6-phosphate" EXACT [GOC:dph]
+xref: MetaCyc:MANNCAT-PWY
+xref: MetaCyc:PWY3O-1743
is_a: GO:0006002 ! fructose 6-phosphate metabolic process
is_a: GO:0019309 ! mannose catabolic process
relationship: has_part GO:0004476 ! mannose-6-phosphate isomerase activity
relationship: has_part GO:0019158 ! mannokinase activity
+property_value: skos:narrowMatch MetaCyc:MANNCAT-PWY
+property_value: skos:narrowMatch MetaCyc:PWY3O-1743
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27638" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
created_by: dph
@@ -367752,13 +382206,14 @@
[Term]
id: GO:0061613
-name: glycolytic process from glycerol
+name: obsolete glycolytic process from glycerol
namespace: biological_process
-def: "The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH." [GOC:dph, ISBN:0201090910]
-is_a: GO:0006096 ! glycolytic process
-is_a: GO:0019563 ! glycerol catabolic process
-relationship: has_part GO:0004807 ! triose-phosphate isomerase activity
-relationship: has_part GO:0061610 ! glycerol to glycerone phosphate metabolic process
+def: "OBSOLETE. The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH." [GOC:dph, ISBN:0201090910]
+comment: This term was obsoleted because it does not represent a glycolytic pathway, it describes how precursors for glycolysis are produced from glycerol.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31214" xsd:anyURI
+is_obsolete: true
+consider: GO:0019589
+consider: GO:0061610
created_by: dph
creation_date: 2014-04-04T08:26:57Z
@@ -367949,7 +382404,10 @@
xref: Reactome:R-HSA-5696838 "BHMT2 tetramer transfers CH3 group from SMM to LHCYS"
xref: RHEA:26337
is_a: GO:0008172 ! S-methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.10
+property_value: skos:exactMatch RHEA:26337
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25824" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2014-05-14T14:32:02Z
@@ -367997,6 +382455,11 @@
synonym: "ER-associated E3 ligase" RELATED [PMID:24019521]
synonym: "protein ubiquitination activity" EXACT [GOC:dph]
synonym: "ubiquitin ligase activity" EXACT [GOC:dph]
+xref: EC:2.3.2.26
+xref: EC:2.3.2.27
+xref: EC:2.3.2.31
+xref: EC:2.3.2.33
+xref: EC:2.3.2.36
xref: Reactome:R-HSA-1225956 "Inefficient ubiquitination of ligand-responsive p-6Y-EGFR mutants by p-Y371-CBL"
xref: Reactome:R-HSA-1504190 "DVL is ubiquitinated by CUL3:KLHL12:RBX1"
xref: Reactome:R-HSA-183036 "Ubiquitination of stimulated EGFR (CBL:GRB2)"
@@ -368090,15 +382553,13 @@
xref: Reactome:R-HSA-9762091 "NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1"
xref: Reactome:R-HSA-9766645 "CUL3:RBX1 ubiquitinates KEAP1"
xref: Reactome:R-HSA-990526 "Recruitment of ITCH and K48 ubiquitination of MAVS"
-xref: Reactome:R-HSA-9929490 "CD274 ubiquitination by SPOP:CUL3:RBX1 complex"
-xref: Reactome:R-HSA-9931298 "Ubiquitination of CD274 by ERAD complex"
-xref: Reactome:R-HSA-9931430 "MIB2-mediated K63-ubiquitination of CD274"
-xref: Reactome:R-HSA-9932510 "BTRC:CUL1:SKP1:RBX1 (SCF-beta-TrCP1) ubiquitinylates phosphorylated PER1,2,3"
-xref: Reactome:R-HSA-9932512 "FBXL3:CUL1:SKP1:RBX1 ubiquitinylates phosphorylated CRY1,2"
-xref: Reactome:R-HSA-9948362 "LTN1 K48 polyubiquitinates the nascent peptide in NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide"
-xref: Reactome:R-HSA-9954737 "RCHY1 K48 polyubiquitinates alanine-tailed nascent peptide"
is_a: GO:0004842 ! ubiquitin-protein transferase activity
is_a: GO:0061659 ! ubiquitin-like protein ligase activity
+property_value: skos:narrowMatch EC:2.3.2.26
+property_value: skos:narrowMatch EC:2.3.2.27
+property_value: skos:narrowMatch EC:2.3.2.31
+property_value: skos:narrowMatch EC:2.3.2.33
+property_value: skos:narrowMatch EC:2.3.2.36
created_by: dph
creation_date: 2014-05-18T09:11:21Z
@@ -368110,8 +382571,13 @@
synonym: "E2" BROAD [GOC:dph]
synonym: "HECT E3" RELATED [GOC:dph]
xref: EC:2.3.2.23
+xref: EC:2.3.2.24
+xref: EC:2.3.2.25
is_a: GO:0004842 ! ubiquitin-protein transferase activity
is_a: GO:0061650 ! ubiquitin-like protein conjugating enzyme activity
+property_value: skos:exactMatch EC:2.3.2.23
+property_value: skos:narrowMatch EC:2.3.2.24
+property_value: skos:narrowMatch EC:2.3.2.25
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30261" xsd:anyURI
created_by: dph
creation_date: 2014-05-18T09:25:19Z
@@ -368141,12 +382607,14 @@
[Term]
id: GO:0061634
-name: alpha-D-xyloside xylohydrolase
+name: alpha-D-xyloside xylohydrolase activity
namespace: molecular_function
def: "Catalysis of the hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose." [EC:3.2.1.177]
synonym: "alpha-xylosidase" RELATED [EC:3.2.1.177]
xref: EC:3.2.1.177
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.177
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2014-07-28T08:12:39Z
@@ -368334,6 +382802,7 @@
xref: EC:2.3.2.34
is_a: GO:0019788 ! NEDD8 transferase activity
is_a: GO:0061650 ! ubiquitin-like protein conjugating enzyme activity
+property_value: skos:exactMatch EC:2.3.2.34
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23338" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25078" xsd:anyURI
created_by: dph
@@ -368433,8 +382902,10 @@
namespace: molecular_function
def: "Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S = X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph]
synonym: "E3" BROAD [GOC:dph]
+xref: EC:2.3.2.32
is_a: GO:0019788 ! NEDD8 transferase activity
is_a: GO:0061659 ! ubiquitin-like protein ligase activity
+property_value: skos:narrowMatch EC:2.3.2.32
created_by: dph
creation_date: 2014-11-06T13:57:00Z
@@ -368572,7 +383043,6 @@
name: importin-alpha family protein binding
namespace: molecular_function
def: "Binding to a member of the importin-alpha family." [PMID:15350979, PMID:17170104, PMID:23734157]
-xref: Reactome:R-HSA-2065539 "SREBP1A,1C,2:Importin beta-1 dissociates"
is_a: GO:0005515 ! protein binding
created_by: dph
creation_date: 2015-01-10T18:25:22Z
@@ -368589,6 +383059,9 @@
xref: MetaCyc:DHDOGALDOL-RXN
xref: RHEA:35583
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.51
+property_value: skos:exactMatch RHEA:35583
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2015-01-15T13:46:25Z
@@ -368696,6 +383169,9 @@
xref: EC:3.1.1.97
xref: RHEA:42656
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.97
+property_value: skos:exactMatch RHEA:42656
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2015-03-04T16:00:21Z
@@ -368710,8 +383186,11 @@
xref: RHEA:42704
is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
relationship: part_of GO:0140479 ! ergothioneine biosynthesis from histidine via hercynylcysteine sulfoxide synthase
+property_value: skos:exactMatch EC:1.21.3.10
+property_value: skos:exactMatch RHEA:42704
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/11163" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24051" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2015-03-06T15:08:51Z
@@ -368755,7 +383234,10 @@
xref: Reactome:R-HSA-9861626 "SIRT4 cleaves lipoyl from DLAT"
xref: RHEA:76519
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.138
+property_value: skos:exactMatch RHEA:76519
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2015-05-05T10:06:49Z
@@ -368790,6 +383272,9 @@
xref: MetaCyc:RXN0-6732
xref: RHEA:34679
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.37
+property_value: skos:exactMatch RHEA:34679
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2015-05-06T10:04:04Z
@@ -368830,7 +383315,9 @@
comment: This reaction is the removal of a glutaryl group from a glutarylated lysine residue of a protein or peptide.
xref: RHEA:47664
is_a: GO:0141218 ! NAD-dependent protein lysine deacylase activity
+property_value: skos:exactMatch RHEA:47664
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28920" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2015-05-07T10:55:53Z
@@ -368945,15 +383432,18 @@
[Term]
id: GO:0061708
-name: tRNA-5-taurinomethyluridine 2-sulfurtransferase
+name: tRNA-5-taurinomethyluridine 2-sulfurtransferase activity
namespace: molecular_function
-def: "Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+." [GOC:dph, PMID:15509579, RHEA:47040]
+def: "Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+." [PMID:15509579, RHEA:47040]
xref: EC:2.8.1.14
xref: MetaCyc:RXN-16821
xref: Reactome:R-HSA-6787447 "TRMU (MTO2, MTU1) transfers a sulfur atom to 5-taurinomethyluridine-34 in tRNA"
xref: RHEA:47040
is_a: GO:0016783 ! sulfurtransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.8.1.14
+property_value: skos:exactMatch RHEA:47040
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30500" xsd:anyURI
created_by: dph
creation_date: 2015-06-16T09:02:23Z
@@ -368978,14 +383468,16 @@
[Term]
id: GO:0061710
-name: L-threonylcarbamoyladenylate synthase
+name: L-threonylcarbamoyladenylate synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H2O." [EC:2.7.7.87]
+def: "Catalysis of the reaction: L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O." [RHEA:36407]
xref: EC:2.7.7.87
xref: MetaCyc:RXN-14569
-xref: Reactome:R-HSA-9611218 "YRDC synthesizes threonylcarbamoyladenylate"
xref: RHEA:36407
is_a: GO:0016779 ! nucleotidyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.87
+property_value: skos:exactMatch RHEA:36407
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2015-06-23T08:25:14Z
@@ -368998,11 +383490,13 @@
synonym: "t6A synthase activity" EXACT []
xref: EC:2.3.1.234
xref: MetaCyc:RXN-14570
-xref: Reactome:R-HSA-6784494 "KEOPS (EKC) complex threonylcarbamoylates A37 of tRNAs"
-xref: Reactome:R-HSA-9611197 "OSGEPL1 threonylcarbamoylates adenosine-37 in tRNA"
+xref: Reactome:R-HSA-6784494 "EKC complex threonylcarbamoylates A37 of tRNAs"
xref: RHEA:37059
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.3.1.234
+property_value: skos:exactMatch RHEA:37059
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2015-06-23T08:34:44Z
@@ -369034,7 +383528,6 @@
namespace: molecular_function
def: "Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis." [GOC:BHF, GOC:hal]
synonym: "folate receptor activity" EXACT []
-xref: Reactome:R-HSA-8940134 "FOLR2 binds FOLA"
is_a: GO:0038024 ! cargo receptor activity
relationship: has_part GO:0005542 ! folic acid binding
relationship: part_of GO:0015884 ! folic acid transport
@@ -369293,9 +383786,10 @@
xref: Reactome:R-HSA-9701531 "p-Y705,S727 STAT3 is acetylated"
xref: Reactome:R-HSA-9756494 "CREBBP acetylates SARS-CoV-2 N at K375"
xref: Reactome:R-HSA-9825747 "CREBBP acetylates HINT1 dimer"
-xref: Reactome:R-HSA-9920716 "CLOCK acetylates BMAL1 on lysine-538"
xref: RHEA:45948
is_a: GO:0034212 ! protein N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.48
+property_value: skos:exactMatch RHEA:45948
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
created_by: dph
creation_date: 2015-09-10T10:22:19Z
@@ -369448,6 +383942,7 @@
namespace: molecular_function
def: "Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis." [GOC:dph, PMID:26277776]
is_a: GO:0003678 ! DNA helicase activity
+property_value: skos:broadMatch EC:3.6.4.12
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: dph
creation_date: 2015-11-11T13:10:51Z
@@ -369693,6 +384188,9 @@
xref: RHEA:25568
is_a: GO:0016301 ! kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.173
+property_value: skos:exactMatch MetaCyc:RXN-8443
+property_value: skos:exactMatch RHEA:25568
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30725" xsd:anyURI
created_by: dph
creation_date: 2016-05-05T14:41:44Z
@@ -369757,6 +384255,7 @@
def: "Facilitating a conformational change to load a cohesin complex around sister chromatids." [GOC:vw, PMID:26687354]
synonym: "cohesin loading activity" EXACT []
is_a: GO:0140097 ! catalytic activity, acting on DNA
+property_value: skos:broadMatch RHEA:13065
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14205" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21700" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23400" xsd:anyURI
@@ -370009,6 +384508,9 @@
xref: MetaCyc:RXN-8340
xref: RHEA:49576
is_a: GO:0016830 ! carbon-carbon lyase activity
+property_value: skos:exactMatch EC:4.1.99.22
+property_value: skos:exactMatch RHEA:49576
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2016-10-06T14:26:11Z
@@ -370021,6 +384523,9 @@
xref: MetaCyc:RXN-17809
xref: RHEA:49580
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
+property_value: skos:exactMatch EC:4.6.1.17
+property_value: skos:exactMatch RHEA:49580
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2016-10-06T14:36:56Z
@@ -370028,19 +384533,22 @@
id: GO:0061800
name: fibronectin fibril
namespace: cellular_component
-def: "A supramolecular fiber formed from fibronectin molecules. The fibrils are 5 to 25nm in diameter and can form branched meshworks." [GOC:dph, PMID:20690820]
+def: "A supramolecular fiber formed from fibronectin molecules. The fibrils are 5 to 25nm in diameter and can form branched meshworks." [PMID:20690820, PMID:26041410, PMID:34572092]
is_a: GO:0099512 ! supramolecular fiber
-relationship: part_of GO:0031012 ! extracellular matrix
+relationship: part_of GO:0140149 ! non-collagenous component of interstitial matrix
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31066" xsd:anyURI
created_by: dph
creation_date: 2016-10-24T14:04:21Z
[Term]
id: GO:0061801
-name: laminin-5B complex
+name: laminin-3B32 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha3B, beta3 and gamma2 polypeptide chains." [GOC:dph, PMID:15979864]
+def: "A laminin complex composed of alpha3B, beta3 and gamma2 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
synonym: "laminin 3B32 complex" EXACT [PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+synonym: "laminin-5B complex" EXACT []
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
created_by: dph
creation_date: 2016-10-26T15:05:15Z
@@ -370144,8 +384652,15 @@
xref: Reactome:R-HSA-8870346 "BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose"
xref: Reactome:R-HSA-8938076 "CD38 hydrolyses NAD+ to NAM and ADP-ribose"
xref: Reactome:R-HSA-9637699 "CpnT hydrolyses NAD+"
+xref: RHEA:38611
+xref: RHEA:38615
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:broadMatch RHEA:16301
+property_value: skos:exactMatch EC:3.2.2.6
+property_value: skos:narrowMatch RHEA:38611
+property_value: skos:narrowMatch RHEA:38615
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26011" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2016-11-11T13:14:13Z
@@ -370636,7 +385151,7 @@
[Term]
id: GO:0061863
-name: microtubule plus end polymerase
+name: microtubule plus end polymerase activity
namespace: molecular_function
def: "Catalysis of the transfer of tubulin dimers to the plus end of a microtubule. The reaction is reversible depending on the availability of dimers." [PMID:27872152]
is_a: GO:0016740 ! transferase activity
@@ -370941,6 +385456,8 @@
def: "Catalysis of the reaction: all-trans-retinol + 2 H+ + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinol + 2 H2O + 2 oxidized [adrenodoxin]." [PMID:27059013]
xref: RHEA:50292
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch RHEA:50292
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2017-06-12T14:49:30Z
@@ -371174,6 +385691,8 @@
def: "Catalysis of the reaction: propionyl-CoA + lysine in peptide = CoA + N-propionyl-lysine-peptide." [PMID:17267393]
xref: RHEA:54020
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch RHEA:54020
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2017-08-02T13:35:22Z
@@ -371201,9 +385720,16 @@
id: GO:0061923
name: (2S,3R,6S,9S)-(-)-protoillud-7-ene synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (2S,3R,6S,9S)-(-)-protoillud-7-ene." [PMID:27862766]
+def: "Catalysis of the reaction: (2E,6E)-farnesyl diphosphate = (2S,3R,6S,9S)-(-)-protoillud-7-ene + diphosphate." [PMID:27862766, RHEA:53628]
synonym: "protoillud-7-ene synthase activity" RELATED []
+xref: EC:4.2.3.160
+xref: MetaCyc:RXN-18787
+xref: RHEA:53628
is_a: GO:0010334 ! sesquiterpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.160
+property_value: skos:exactMatch MetaCyc:RXN-18787
+property_value: skos:exactMatch RHEA:53628
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: dph
creation_date: 2017-08-02T15:48:21Z
@@ -371270,9 +385796,11 @@
namespace: molecular_function
def: "Catalysis of the reaction: glutathione = 5-oxoproline + L-cysteinylglycine." [PMID:23070364, PMID:27913623]
xref: EC:4.3.2.7
-xref: Reactome:R-HSA-6785928 "CHAC1,2 cleaves GSH to OPRO and CysGly"
xref: RHEA:47724
is_a: GO:0016842 ! amidine-lyase activity
+property_value: skos:exactMatch EC:4.3.2.7
+property_value: skos:exactMatch RHEA:47724
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2017-08-29T14:55:30Z
@@ -371284,6 +385812,9 @@
xref: EC:4.3.2.8
xref: RHEA:16961
is_a: GO:0016842 ! amidine-lyase activity
+property_value: skos:exactMatch EC:4.3.2.8
+property_value: skos:exactMatch RHEA:16961
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2017-08-29T14:57:39Z
@@ -371514,12 +386045,6 @@
name: mRNA (adenine-N1-)-methyltransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: S-adenosyl-L-methionine + adenine in mRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine in mRNA." [PMID:29072297]
-xref: Reactome:R-HSA-9937508 "TRMT61B methylates adenosine-1472 of MT-CO1 mRNA"
-xref: Reactome:R-HSA-9937512 "TRMT61B methylates adenosine-371 of MT-ND1 mRNA"
-xref: Reactome:R-HSA-9937518 "TRMT61B methylates adenosine-333, adenosine-458, and adenosine-707 of MT-CO3 mRNA"
-xref: Reactome:R-HSA-9937521 "TRMT61B methylates adenosine-185 of MT-CO2 mRNA"
-xref: Reactome:R-HSA-9937529 "TRMT61B methylates adenosine-616 and adenosine-617 of MT-CYB mRNA"
-xref: Reactome:R-HSA-9937535 "TRMT61B methylates adenosine-252 of MT-ND4L mRNA"
is_a: GO:0008174 ! mRNA methyltransferase activity
created_by: dph
creation_date: 2017-11-08T13:26:35Z
@@ -371884,6 +386409,8 @@
xref: MetaCyc:RXN-13613
xref: RHEA:42264
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.207
+property_value: skos:exactMatch RHEA:42264
created_by: dph
creation_date: 2018-02-15T22:29:03Z
@@ -372336,7 +386863,7 @@
[Term]
id: GO:0062045
-name: L-lysine alpha-aminotransferase
+name: L-lysine alpha-aminotransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: L-lysine + pyruvate= epsilon-amino-alpha-ketocaproic acid (KAC) + alanine." [PMID:27758894, PMID:28330936]
is_a: GO:0008483 ! transaminase activity
@@ -372345,7 +386872,7 @@
[Term]
id: GO:0062046
-name: dehydropipecolic acid reductase
+name: dehydropipecolic acid reductase activity
namespace: molecular_function
def: "Catalysis of the reaction: dehydropipecolic acid + NAD(P)H + H+ = L-pipecolic acid + NAD(P)+." [PMID:27758894, PMID:28330936]
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
@@ -372354,7 +386881,7 @@
[Term]
id: GO:0062047
-name: pipecolic acid N-hydroxylase
+name: pipecolic acid N-hydroxylase activity
namespace: molecular_function
def: "Catalysis of the reaction: L-pipecolic acid + NAD(P)H + O2 + H+ = N-hydroxypipecolic acid + NAD(P)+ + H2O." [PMID:27758894, PMID:28330936]
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
@@ -372628,9 +387155,15 @@
synonym: "acyl-CoA delta(5)-desaturase activity" EXACT []
synonym: "acyl-CoA delta5-desaturase activity" EXACT []
xref: EC:1.14.19.44
+xref: RHEA:46420
+xref: RHEA:46424
is_a: GO:0016215 ! acyl-CoA desaturase activity
+property_value: skos:exactMatch EC:1.14.19.44
+property_value: skos:narrowMatch RHEA:46420
+property_value: skos:narrowMatch RHEA:46424
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24103" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29820" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2018-09-24T15:33:59Z
@@ -372919,7 +387452,10 @@
xref: RHEA:11508
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:1.14.11.16
+property_value: skos:exactMatch RHEA:11508
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17842" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2018-12-06T14:01:15Z
@@ -372950,6 +387486,8 @@
xref: RHEA:58956
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008173 ! RNA methyltransferase activity
+property_value: skos:exactMatch RHEA:58956
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-01-23T14:23:00Z
@@ -373020,7 +387558,6 @@
synonym: "FAPA biosynthesis" EXACT []
synonym: "FAPA biosynthetic process" EXACT []
synonym: "fatty acid amide biosynthesis" EXACT []
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0062126 ! fatty acid primary amide metabolic process
is_a: GO:1901570 ! fatty acid derivative biosynthetic process
created_by: dph
@@ -373139,7 +387676,6 @@
namespace: biological_process
def: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform primary fatty amides." [PMID:11128635]
synonym: "primary fatty amide metabolic process" EXACT []
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:1901568 ! fatty acid derivative metabolic process
created_by: dph
creation_date: 2019-05-30T18:23:02Z
@@ -373198,6 +387734,8 @@
xref: MetaCyc:RXNQT-4343
xref: RHEA:60628
is_a: GO:0051213 ! dioxygenase activity
+property_value: skos:exactMatch RHEA:60628
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-06-24T16:45:18Z
@@ -373324,6 +387862,8 @@
def: "Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate = chloride + H+ + L-propargylglycine." [PMID:30867596, RHEA:59892]
xref: RHEA:59892
is_a: GO:0016848 ! carbon-halide lyase activity
+property_value: skos:exactMatch RHEA:59892
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-09-02T16:48:52Z
@@ -373334,6 +387874,8 @@
def: "Catalysis of the reaction: ATP + L-glutamate + L-propargylglycine = ADP + H+ + L-gamma-glutamyl-L-propargylglycine + phosphate." [PMID:30867596, RHEA:59896]
xref: RHEA:59896
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch RHEA:59896
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-09-02T16:56:59Z
@@ -373344,6 +387886,8 @@
def: "Catalysis of the reaction: 4-chloro-L-lysine + AH2 + O2 = A + formaldehyde + H2O + L-2-amino-4-chloropent-4-enoate + NH4(+)." [PMID:30867596, RHEA:59888]
xref: RHEA:59888
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch RHEA:59888
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-09-02T16:59:30Z
@@ -373354,6 +387898,8 @@
def: "Catalysis of the reaction: 2-oxoglutarate + chloride + H+ + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate." [PMID:30867596, RHEA:59884]
xref: RHEA:59884
is_a: GO:0050498 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated
+property_value: skos:exactMatch RHEA:59884
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-09-02T17:01:46Z
@@ -373364,6 +387910,8 @@
def: "Catalysis of the reaction: 2-oxoglutarate + L-gamma-glutamyl-L-propargylglycine + O2 = CO2 + L-gamma-glutamyl-(3R)-L-beta-ethynylserine + succinate." [PMID:30867596, RHEA:59900]
xref: RHEA:59900
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch RHEA:59900
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-09-02T17:04:43Z
@@ -373387,6 +387935,9 @@
xref: EC:1.14.14.114
xref: RHEA:32999
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:exactMatch EC:1.14.14.114
+property_value: skos:exactMatch RHEA:32999
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-09-13T14:48:12Z
@@ -373407,6 +387958,8 @@
synonym: "mRNA (cytosine-5-)-methyltransferase activity" EXACT []
xref: RHEA:61464
is_a: GO:0008174 ! mRNA methyltransferase activity
+property_value: skos:exactMatch RHEA:61464
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-09-18T14:40:32Z
@@ -373436,8 +387989,10 @@
xref: Reactome:R-HSA-9731661 "ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine"
xref: RHEA:16001
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch RHEA:16001
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19833" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21501" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-09-20T13:16:37Z
@@ -373753,6 +388308,8 @@
def: "Catalysis of the reaction: calcidiol + 2 H+ + O2 + 2 reduced [adrenodoxin] = (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin]." [PMID:22100522, PMID:30205156, RHEA:46616]
xref: RHEA:46616
is_a: GO:0062179 ! vitamin D 23-hydroxylase activity
+property_value: skos:exactMatch RHEA:46616
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-11-26T17:12:22Z
@@ -373763,6 +388320,8 @@
def: "Catatlysis of the reaction: calcitriol + 2 H+ + O2 + 2 reduced [adrenodoxin] = 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]." [PMID:22100522, PMID:30205156, RHEA:49192]
xref: RHEA:49192
is_a: GO:0062179 ! vitamin D 23-hydroxylase activity
+property_value: skos:exactMatch RHEA:49192
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-11-26T17:16:39Z
@@ -373773,6 +388332,8 @@
def: "Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-(4S)-hydroxyretinoate + H+ + H2O + oxidized [NADPH--hemoprotein reductase]." [PMID:9250660, PMID:9716180, RHEA:51492]
xref: RHEA:51492
is_a: GO:0008401 ! retinoic acid 4-hydroxylase activity
+property_value: skos:exactMatch RHEA:51492
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-11-26T18:36:06Z
@@ -373783,6 +388344,8 @@
def: "Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H+ + H2O + oxidized [NADPH--hemoprotein reductase]." [PMID:22020119, RHEA:55856]
xref: RHEA:55856
is_a: GO:0004497 ! monooxygenase activity
+property_value: skos:exactMatch RHEA:55856
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-11-26T18:41:32Z
@@ -373793,7 +388356,9 @@
def: "Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H+ + H2O + oxidized [NADPH--hemoprotein reductase]." [PMID:21289075, RHEA:46304]
xref: RHEA:46304
is_a: GO:0008395 ! steroid hydroxylase activity
+property_value: skos:exactMatch RHEA:46304
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29311" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-11-26T18:43:43Z
@@ -373804,6 +388369,8 @@
def: "Catalysis of the reaction:2 H+ + O2 + 2 reduced [adrenodoxin] + secalciferol = calcitetrol + H2O + 2 oxidized [adrenodoxin]." [PMID:10518789, RHEA:49064]
xref: RHEA:49064
is_a: GO:0004497 ! monooxygenase activity
+property_value: skos:exactMatch RHEA:49064
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-11-26T18:46:18Z
@@ -373824,6 +388391,8 @@
def: "Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]." [PMID:21289075, RHEA:53140]
xref: RHEA:53140
is_a: GO:0062186 ! anandamide epoxidase activity
+property_value: skos:exactMatch RHEA:53140
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-11-26T18:51:34Z
@@ -373834,6 +388403,8 @@
def: "Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + N-(11,12-epoxy-5Z,8Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]." [PMID:21289075, RHEA:53144]
xref: RHEA:53144
is_a: GO:0062186 ! anandamide epoxidase activity
+property_value: skos:exactMatch RHEA:53144
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-11-26T18:53:52Z
@@ -373844,6 +388415,8 @@
def: "Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + N-(14,15-epoxy-5Z,8Z,11Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]." [PMID:21289075, RHEA:53148]
xref: RHEA:53148
is_a: GO:0062186 ! anandamide epoxidase activity
+property_value: skos:exactMatch RHEA:53148
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-11-26T18:57:55Z
@@ -373870,6 +388443,9 @@
xref: EC:5.1.3.32
xref: RHEA:25584
is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
+property_value: skos:exactMatch EC:5.1.3.32
+property_value: skos:exactMatch RHEA:25584
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2019-12-09T16:45:45Z
@@ -373879,7 +388455,12 @@
namespace: molecular_function
def: "Catalysis of the reactions: beta-D-ribopyranose = beta-D-ribofuranose, and beta-allofuranose = beta-allopyranose." [EC:5.4.99.62]
xref: EC:5.4.99.62
+xref: RHEA:25432
+xref: RHEA:25609
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.62
+property_value: skos:narrowMatch RHEA:25432
+property_value: skos:narrowMatch RHEA:25609
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
created_by: dph
creation_date: 2019-12-09T16:49:07Z
@@ -373969,6 +388550,8 @@
def: "Catalysis of the reaction: peregrinol diphosphate = diphosphate + labd-13(16),14-diene-9-ol." [PMID:29315936, RHEA:62184]
xref: RHEA:62184
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch RHEA:62184
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2020-01-02T15:46:00Z
@@ -373979,6 +388562,8 @@
def: "Catalysis of the reaction: H2O + peregrinol diphosphate = diphosphate + viteagnusin D." [PMID:29315936, RHEA:62180]
xref: RHEA:62180
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch RHEA:62180
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2020-01-02T18:25:47Z
@@ -373989,6 +388574,8 @@
def: "Catalysis of the reaction:9alpha-copalyl diphosphate + H2O = (13S)-vitexifolin A + diphosphate." [PMID:29315936, RHEA:40027]
xref: RHEA:40027
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch RHEA:40027
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2020-01-03T13:24:50Z
@@ -374003,6 +388590,9 @@
xref: MetaCyc:RXN-13338
xref: RHEA:33983
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.131
+property_value: skos:exactMatch RHEA:33983
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2020-01-03T14:05:49Z
@@ -374014,6 +388604,9 @@
xref: EC:4.2.3.190
xref: RHEA:54516
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.190
+property_value: skos:exactMatch RHEA:54516
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2020-01-03T14:48:52Z
@@ -374095,6 +388688,8 @@
def: "Catalysis of the reaction: peroxynitrite = nitrate." [PMID:30524950, RHEA:63116]
xref: RHEA:63116
is_a: GO:0016853 ! isomerase activity
+property_value: skos:exactMatch RHEA:63116
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dph
creation_date: 2020-02-22T13:57:50Z
@@ -374843,6 +389438,7 @@
is_a: GO:0016435 ! rRNA (guanine) methyltransferase activity
is_a: GO:0062105 ! RNA 2'-O-methyltransferase activity
relationship: part_of GO:0000451 ! rRNA 2'-O-methylation
+property_value: skos:broadMatch RHEA:58956
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -374855,6 +389451,8 @@
xref: RHEA:42916
is_a: GO:0008169 ! C-methyltransferase activity
is_a: GO:0016433 ! rRNA (adenine) methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.192
+property_value: skos:exactMatch RHEA:42916
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26114" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/9902" xsd:anyURI
@@ -375668,6 +390266,7 @@
synonym: "type III TGFbeta receptor activity" EXACT []
synonym: "type III transforming growth factor beta receptor activity" EXACT []
is_a: GO:0005024 ! transforming growth factor beta receptor activity
+property_value: skos:broadMatch EC:2.7.11.30
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -376485,6 +391084,9 @@
xref: MetaCyc:2.5.1.64-RXN
xref: RHEA:25593
is_a: GO:0016744 ! transketolase or transaldolase activity
+property_value: skos:exactMatch EC:2.2.1.9
+property_value: skos:exactMatch RHEA:25593
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0070205
@@ -376501,6 +391103,9 @@
xref: MetaCyc:RXN-9310
xref: RHEA:25597
is_a: GO:0016835 ! carbon-oxygen lyase activity
+property_value: skos:exactMatch EC:4.2.99.20
+property_value: skos:exactMatch RHEA:25597
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0070206
@@ -376701,11 +391306,15 @@
comment: Note that EC:1.8.5.4 describes this reaction as bacterial-specific, but it has also been observed in eukaryotes (PMID:22852582, PMID:10224084).
synonym: "sulfide-quinone reductase activity" EXACT [MetaCyc:MONOMER-12314]
synonym: "sulphide:quinone oxidoreductase activity" EXACT [GOC:mah]
+xref: EC:1.8.5.4
xref: MetaCyc:R17-RXN
xref: Reactome:R-HSA-1614665 "SQR oxidizes sulfide to bound persulfide"
xref: RHEA:30239
is_a: GO:0016672 ! oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor
+property_value: skos:exactMatch RHEA:30239
+property_value: skos:narrowMatch EC:1.8.5.4
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23325" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0070225
@@ -376718,6 +391327,9 @@
xref: MetaCyc:RXN-8156
xref: RHEA:30223
is_a: GO:0016669 ! oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.8.2.3
+property_value: skos:exactMatch RHEA:30223
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0070226
@@ -377126,6 +391738,8 @@
xref: RHEA:47264
is_a: GO:0016405 ! CoA-ligase activity
is_a: GO:0016878 ! acid-thiol ligase activity
+property_value: skos:exactMatch RHEA:47264
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0070252
@@ -377428,6 +392042,8 @@
xref: EC:4.1.99.17
xref: RHEA:24840
is_a: GO:0016830 ! carbon-carbon lyase activity
+property_value: skos:exactMatch EC:4.1.99.17
+property_value: skos:exactMatch RHEA:24840
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29695" xsd:anyURI
[Term]
@@ -377478,7 +392094,7 @@
id: GO:0070290
name: N-acylphosphatidylethanolamine-specific phospholipase D activity
namespace: molecular_function
-def: "Catalysis of the reaction: H2O + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine (NAPE) = a 1,2-diacyl-sn-glycero-3-phosphate + an N-acylethanolamine (NAE) + H+." [PMID:14634025, PMID:15878693, RHEA:33159]
+def: "Catalysis of the reaction: an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine (NAPE) + H2O = an N-acylethanolamine (NAE) + a 1,2-diacyl-sn-glycero-3-phosphate + H+." [PMID:14634025, PMID:15878693, RHEA:33159]
subset: goslim_chembl
synonym: "N-acyl-phosphatidylethanolamine-specific phospholipase D activity" EXACT []
synonym: "NAPE-specific phospholipase D activity" EXACT []
@@ -377486,9 +392102,11 @@
xref: MetaCyc:RXN-12116
xref: Reactome:R-HSA-2466831 "A2PE hydrolyses to A2E"
xref: RHEA:33159
-is_a: GO:0004620 ! phospholipase activity
-is_a: GO:0008081 ! phosphoric diester hydrolase activity
+is_a: GO:0004630 ! D-type glycerophospholipase activity
+property_value: skos:exactMatch EC:3.1.4.54
+property_value: skos:exactMatch RHEA:33159
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27559" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0070291
@@ -377508,7 +392126,6 @@
synonym: "N-acylphosphatidylethanolamine metabolism" EXACT [GOC:elh, PMID:14634025, PMID:15878693]
synonym: "NAPE metabolic process" EXACT [GOC:elh, PMID:14634025, PMID:15878693]
synonym: "NAPE metabolism" EXACT [GOC:elh, PMID:14634025, PMID:15878693]
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0046337 ! phosphatidylethanolamine metabolic process
[Term]
@@ -377923,7 +392540,12 @@
def: "Catalysis of the reaction: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + testosterone = 17beta-estradiol + formate + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]. Also converts androst-4-ene-3,17-dione into estrone." [EC:1.14.14.14]
synonym: "estrogen synthetase activity" NARROW []
xref: EC:1.14.14.14
+xref: RHEA:38191
+xref: RHEA:38195
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.14
+property_value: skos:narrowMatch RHEA:38191
+property_value: skos:narrowMatch RHEA:38195
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28295" xsd:anyURI
[Term]
@@ -379177,6 +393799,8 @@
xref: RHEA:25633
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.267
+property_value: skos:exactMatch RHEA:25633
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -379699,12 +394323,16 @@
id: GO:0070497
name: 6-carboxytetrahydropterin synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+." [GOC:imk, PMID:19231875, RHEA:27966]
+def: "Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+." [PMID:19231875, RHEA:27966]
synonym: "6-carboxy-5,6,7,8-tetrahydropterin synthase activity" EXACT []
xref: EC:4.1.2.50
xref: MetaCyc:RXN0-5507
xref: RHEA:27966
-is_a: GO:0016836 ! hydro-lyase activity
+is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.50
+property_value: skos:exactMatch RHEA:27966
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31104" xsd:anyURI
[Term]
id: GO:0070498
@@ -379960,10 +394588,10 @@
name: 11-beta-hydroxysteroid dehydrogenase (NAD+) activity
namespace: molecular_function
def: "Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+." [PMID:15761036, RHEA:53116]
-xref: Reactome:R-HSA-194023 "HSD11B2,HSD11B1 dimer oxidise CORT to COR"
xref: RHEA:53116
xref: Wikipedia:11beta-hydroxysteroid_dehydrogenase
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:53116
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21915" xsd:anyURI
[Term]
@@ -379980,6 +394608,9 @@
xref: RHEA:11388
xref: Wikipedia:11beta-hydroxysteroid_dehydrogenase
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.146
+property_value: skos:exactMatch MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN
+property_value: skos:exactMatch RHEA:11388
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28173" xsd:anyURI
@@ -380374,7 +395005,6 @@
name: adenylyltransferase activity
namespace: molecular_function
def: "Catalysis of the transfer of an adenylyl group to an acceptor." [GOC:mah]
-xref: Reactome:R-HSA-9935837 "The TRAMP:RNA exosome oligoadenylates pre-rRNA 5' external transcribed spacer (5'ETS) fragment"
is_a: GO:0016779 ! nucleotidyltransferase activity
created_by: mah
creation_date: 2009-04-15T11:04:22Z
@@ -380460,9 +395090,9 @@
def: "Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE]
synonym: "metallo-exo-dipeptidase activity" EXACT [GOC:rb]
synonym: "metalloexodipeptidase activity" EXACT [GOC:mah]
-xref: Reactome:R-HSA-2022398 "ACE:Zn2+ hydrolyzes AGT(25-33) (Angiotensin-(1-9)) to AGT(25-31) (Angiotensin-(1-7))"
-xref: Reactome:R-HSA-2022405 "ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8))"
-xref: Reactome:R-HSA-2065355 "Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8))"
+xref: Reactome:R-HSA-2022398 "ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7)"
+xref: Reactome:R-HSA-2022405 "ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)"
+xref: Reactome:R-HSA-2065355 "Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)"
is_a: GO:0008235 ! metalloexopeptidase activity
is_a: GO:0016805 ! dipeptidase activity
created_by: mah
@@ -380486,7 +395116,7 @@
name: obsolete peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation
namespace: biological_process
def: "OBSOLETE. The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation." [GOC:mah]
-comment: The reason for obsoletion is that this term represents a GO-CAM model.
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "peptide mating pheromone formation involved in pheromone-induced unidirectional conjugation" EXACT [GOC:mah]
synonym: "peptide mating pheromone processing involved in pheromone-induced unidirectional conjugation" EXACT [GOC:mah]
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30459" xsd:anyURI
@@ -380504,7 +395134,9 @@
synonym: "ergocalciferol 24-hydroxylase activity" NARROW [GOC:rl]
synonym: "vitamin D2 24-hydroxylase activity" NARROW [GOC:rl]
synonym: "vitamin D3 24-hydroxylase activity" NARROW [GOC:rl]
+xref: EC:1.14.15.16
is_a: GO:0008395 ! steroid hydroxylase activity
+property_value: skos:narrowMatch EC:1.14.15.16
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28340" xsd:anyURI
created_by: mah
creation_date: 2009-04-21T02:20:52Z
@@ -380546,9 +395178,16 @@
xref: Reactome:R-HSA-5220990 "TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine"
xref: Reactome:R-HSA-5221014 "TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine"
xref: Reactome:R-HSA-9817458 "TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3"
+xref: RHEA:52636
+xref: RHEA:53828
+xref: RHEA:53832
xref: WIkipedia:DNA_demethylation
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0140097 ! catalytic activity, acting on DNA
+property_value: skos:exactMatch EC:1.14.11.80
+property_value: skos:narrowMatch RHEA:52636
+property_value: skos:narrowMatch RHEA:53828
+property_value: skos:narrowMatch RHEA:53832
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23312" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24855" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26656" xsd:anyURI
@@ -381001,6 +395640,9 @@
synonym: "histone-H3R2 methyltransferase activity" EXACT []
is_a: GO:0016274 ! protein-arginine N-methyltransferase activity
is_a: GO:0140938 ! histone H3 methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.319
+property_value: skos:broadMatch EC:2.1.1.320
+property_value: skos:broadMatch RHEA:48108
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: mah
@@ -381019,6 +395661,7 @@
synonym: "histone-H2AR3 methyltransferase activity" EXACT []
is_a: GO:0016274 ! protein-arginine N-methyltransferase activity
is_a: GO:0140940 ! histone H2A methyltransferase activity
+property_value: skos:broadMatch RHEA:48108
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: mah
creation_date: 2009-04-29T02:06:45Z
@@ -381209,6 +395852,8 @@
xref: Reactome:R-HSA-73828 "adenylosuccinate => adenosine 5'-monophosphate + fumarate"
xref: RHEA:23920
is_a: GO:0016842 ! amidine-lyase activity
+property_value: skos:broadMatch EC:4.3.2.2
+property_value: skos:exactMatch RHEA:23920
created_by: mah
creation_date: 2009-05-01T04:13:49Z
@@ -381801,6 +396446,7 @@
def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine." [GOC:mah, PMID:19400805]
is_a: GO:0016434 ! rRNA (cytosine) methyltransferase activity
is_a: GO:0062105 ! RNA 2'-O-methyltransferase activity
+property_value: skos:broadMatch RHEA:58956
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: mah
creation_date: 2009-05-29T03:37:53Z
@@ -381938,7 +396584,6 @@
xref: MetaCyc:PWY-5436
is_a: GO:0006084 ! acetyl-CoA metabolic process
is_a: GO:0006567 ! L-threonine catabolic process
-is_a: GO:0043605 ! amide catabolic process
created_by: mah
creation_date: 2009-06-03T01:40:22Z
@@ -381989,6 +396634,7 @@
xref: Reactome:R-HSA-8953339 "DNPH1 hydrolyses dGMP"
xref: RHEA:77099
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch RHEA:77099
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29145" xsd:anyURI
created_by: mah
creation_date: 2009-06-04T03:06:57Z
@@ -382393,7 +397039,14 @@
synonym: "AMPylator" RELATED [GOC:mah]
synonym: "protein adenylyltransferase activity" RELATED []
xref: EC:2.7.7.108
+xref: RHEA:54288
+xref: RHEA:54292
+xref: RHEA:58120
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.108
+property_value: skos:narrowMatch RHEA:54288
+property_value: skos:narrowMatch RHEA:54292
+property_value: skos:narrowMatch RHEA:58120
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25168" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25802" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28233" xsd:anyURI
@@ -382424,7 +397077,9 @@
xref: RHEA:67180
is_a: GO:0016881 ! acid-amino acid ligase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch RHEA:67180
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25720" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2009-06-19T01:51:21Z
@@ -382455,6 +397110,7 @@
def: "Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin." [GOC:mah, PMID:19524510]
synonym: "tubulin glycylase activity" EXACT [GOC:mah]
is_a: GO:0070735 ! protein-glycine ligase activity
+property_value: skos:broadMatch RHEA:67180
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: mah
creation_date: 2009-06-19T02:02:01Z
@@ -382482,7 +397138,9 @@
xref: Reactome:R-HSA-8865774 "TTLLs polyglutamylate tubulin"
xref: Reactome:R-HSA-8955869 "Polyglutamylase complex (TTLL1) polyglutamylates alpha subunits of tubulin"
is_a: GO:0070739 ! protein-glutamic acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.61
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23409" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2009-06-19T02:26:15Z
@@ -382856,7 +397514,10 @@
xref: RHEA:50680
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:3.5.1.122
+property_value: skos:exactMatch RHEA:50680
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23341" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2009-06-30T11:34:08Z
@@ -382866,6 +397527,7 @@
namespace: molecular_function
def: "OBSOLETE. Catalysis of the reaction: a phytoceramide + H2O = a fatty acid + phytosphingosine." [GOC:pde, PMID:11356846]
comment: The reason for obsoletion is that this term represents a specific substrate of GO:0017040 N-acylsphingosine amidohydrolase activity.
+xref: Reactome:R-HSA-428262 "ACER3 hydrolyzes phytoceramide"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28294" xsd:anyURI
is_obsolete: true
replaced_by: GO:0017040
@@ -382938,7 +397600,9 @@
xref: MetaCyc:DHS-PHOSPHATASE-RXN
xref: RHEA:27514
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch RHEA:27514
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28183" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2009-07-02T02:13:49Z
@@ -383381,6 +398045,7 @@
xref: RHEA:58360
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch RHEA:58360
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29801" xsd:anyURI
created_by: mah
creation_date: 2009-07-09T11:42:07Z
@@ -383434,6 +398099,7 @@
synonym: "protoporphyrinogen-IX:menaquinone oxidoreductase activity" EXACT [GOC:mah]
is_a: GO:0016635 ! oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor
is_a: GO:0070818 ! protoporphyrinogen oxidase activity
+property_value: skos:broadMatch EC:1.3.3.4
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24056" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: mah
@@ -384454,6 +399120,8 @@
is_a: GO:0015297 ! antiporter activity
is_a: GO:0015556 ! C4-dicarboxylate transmembrane transporter activity
is_a: GO:0022858 ! alanine transmembrane transporter activity
+property_value: skos:exactMatch RHEA:33139
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2009-09-04T03:44:15Z
@@ -384747,7 +399415,7 @@
synonym: "co-translational protein tagging" EXACT [GOC:jh2, GOC:jsg]
synonym: "cotranslational protein tagging" EXACT [GOC:mah]
synonym: "protein modification by trans-translation" EXACT [GOC:mah]
-is_a: GO:0072344 ! rescue of stalled ribosome
+is_a: GO:0072344 ! rescue of stalled cytosolic ribosome
relationship: has_part GO:0070929 ! trans-translation
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/8059" xsd:anyURI
created_by: mah
@@ -384894,7 +399562,7 @@
namespace: biological_process
def: "The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:add, ISBN:0781765196]
synonym: "neutrophil mediated killing of symbiont cell" EXACT []
-is_a: GO:0051873 ! killing by host of symbiont cells
+is_a: GO:0031640 ! killing of cells of another organism
is_a: GO:0070942 ! neutrophil mediated cytotoxicity
created_by: mah
creation_date: 2009-10-01T01:52:03Z
@@ -384962,9 +399630,6 @@
name: regulation of neutrophil mediated killing of symbiont cell
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil." [GOC:add, GOC:mah]
-is_a: GO:0002831 ! regulation of response to biotic stimulus
-is_a: GO:0031347 ! regulation of defense response
-is_a: GO:0032101 ! regulation of response to external stimulus
is_a: GO:0043903 ! regulation of biological process involved in symbiotic interaction
is_a: GO:0051709 ! regulation of killing of cells of another organism
is_a: GO:0070948 ! regulation of neutrophil mediated cytotoxicity
@@ -385051,9 +399716,6 @@
synonym: "down-regulation of neutrophil mediated killing of symbiont cell" EXACT [GOC:mah]
synonym: "downregulation of neutrophil mediated killing of symbiont cell" EXACT [GOC:mah]
synonym: "inhibition of neutrophil mediated killing of symbiont cell" NARROW [GOC:mah]
-is_a: GO:0002832 ! negative regulation of response to biotic stimulus
-is_a: GO:0031348 ! negative regulation of defense response
-is_a: GO:0032102 ! negative regulation of response to external stimulus
is_a: GO:0051711 ! negative regulation of killing of cells of another organism
is_a: GO:0070949 ! regulation of neutrophil mediated killing of symbiont cell
is_a: GO:0070954 ! negative regulation of neutrophil mediated cytotoxicity
@@ -385161,9 +399823,6 @@
synonym: "up regulation of neutrophil mediated killing of symbiont cell" EXACT [GOC:mah]
synonym: "up-regulation of neutrophil mediated killing of symbiont cell" EXACT [GOC:mah]
synonym: "upregulation of neutrophil mediated killing of symbiont cell" EXACT [GOC:mah]
-is_a: GO:0002833 ! positive regulation of response to biotic stimulus
-is_a: GO:0031349 ! positive regulation of defense response
-is_a: GO:0032103 ! positive regulation of response to external stimulus
is_a: GO:0051712 ! positive regulation of killing of cells of another organism
is_a: GO:0070949 ! regulation of neutrophil mediated killing of symbiont cell
is_a: GO:0070960 ! positive regulation of neutrophil mediated cytotoxicity
@@ -385399,7 +400058,6 @@
synonym: "L-asparagine formation" EXACT [GOC:mah]
synonym: "L-asparagine synthesis" EXACT [GOC:mah]
is_a: GO:0009067 ! aspartate family amino acid biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0070982 ! L-asparagine metabolic process
created_by: mah
creation_date: 2009-10-27T12:59:42Z
@@ -385411,7 +400069,6 @@
def: "The chemical reactions and pathways involving L-asparagine, (2S)-2-amino-3-carbamoylpropanoic acid." [GOC:mah]
synonym: "L-asparagine metabolism" EXACT [GOC:mah]
is_a: GO:0006528 ! asparagine metabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0170033 ! L-amino acid metabolic process
is_a: GO:0170039 ! proteinogenic amino acid metabolic process
created_by: mah
@@ -385514,6 +400171,9 @@
xref: MetaCyc:RXN-11734
xref: RHEA:14477
is_a: GO:0003995 ! acyl-CoA dehydrogenase activity
+property_value: skos:exactMatch EC:1.3.8.7
+property_value: skos:exactMatch MetaCyc:RXN-11734
+property_value: skos:exactMatch RHEA:14477
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23273" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
created_by: mah
@@ -385598,14 +400258,14 @@
[Term]
id: GO:0070999
-name: detection of mechanical stimulus involved in sensory perception of gravity
+name: obsolete detection of mechanical stimulus involved in sensory perception of gravity
namespace: biological_process
-def: "The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal." [GOC:dos, GOC:mah]
-is_a: GO:0009590 ! detection of gravity
-is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception
-intersection_of: GO:0050982 ! detection of mechanical stimulus
-intersection_of: part_of GO:0070998 ! sensory perception of gravity
-relationship: part_of GO:0070998 ! sensory perception of gravity
+def: "OBSOLETE. The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal." [GOC:dos, GOC:mah]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0050982
+consider: GO:0070998
created_by: mah
creation_date: 2009-11-03T03:27:30Z
@@ -386391,9 +401051,10 @@
[Term]
id: GO:0071066
-name: detection of mechanical stimulus involved in sensory perception of wind
+name: obsolete detection of mechanical stimulus involved in sensory perception of wind
namespace: biological_process
-def: "The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal." [GOC:dos, GOC:mah, PMID:19279637]
+def: "OBSOLETE. The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal." [GOC:dos, GOC:mah, PMID:19279637]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "detection of mechanical stimulus involved in sensory perception of air flow" EXACT [GOC:mah]
synonym: "detection of wind" EXACT [GOC:mah]
synonym: "perception of wind, detection of mechanical stimulus" EXACT [GOC:mah]
@@ -386402,11 +401063,10 @@
synonym: "sensory detection of mechanical stimulus during perception of wind" EXACT [GOC:mah]
synonym: "sensory transduction of mechanical stimulus during perception of wind" EXACT [GOC:mah]
synonym: "sensory transduction of wind" EXACT [GOC:mah]
-is_a: GO:0050877 ! nervous system process
-is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception
-intersection_of: GO:0050982 ! detection of mechanical stimulus
-intersection_of: part_of GO:0071063 ! sensory perception of wind
-relationship: part_of GO:0071063 ! sensory perception of wind
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0050982
+consider: GO:0071063
created_by: mah
creation_date: 2009-11-04T02:47:36Z
@@ -386917,6 +401577,9 @@
xref: MetaCyc:RXN0-4181
xref: RHEA:24902
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.52
+property_value: skos:exactMatch RHEA:24902
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2009-11-13T02:10:39Z
@@ -387314,6 +401977,9 @@
xref: EC:6.3.2.29
xref: RHEA:13277
is_a: GO:0043860 ! cyanophycin synthetase activity
+property_value: skos:exactMatch EC:6.3.2.29
+property_value: skos:exactMatch RHEA:13277
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2009-11-17T05:18:17Z
@@ -387325,6 +401991,9 @@
xref: EC:6.3.2.30
xref: RHEA:23888
is_a: GO:0043860 ! cyanophycin synthetase activity
+property_value: skos:exactMatch EC:6.3.2.30
+property_value: skos:exactMatch RHEA:23888
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2009-11-17T05:19:54Z
@@ -387366,9 +402035,17 @@
synonym: "RNA trimethylguanosine synthase activity" EXACT []
synonym: "small nuclear RNA methyltransferase activity" RELATED [GOC:rl]
synonym: "snRNA methyltransferase activity" RELATED [GOC:rl]
+xref: RHEA:78471
+xref: RHEA:78475
+xref: RHEA:78479
+xref: RHEA:78507
is_a: GO:0008173 ! RNA methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
relationship: part_of GO:0036261 ! 7-methylguanosine cap hypermethylation
+property_value: skos:narrowMatch RHEA:78471
+property_value: skos:narrowMatch RHEA:78475
+property_value: skos:narrowMatch RHEA:78479
+property_value: skos:narrowMatch RHEA:78507
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25717" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26934" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28404" xsd:anyURI
@@ -387458,8 +402135,15 @@
id: GO:0071172
name: dihydromonapterin reductase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+." [GOC:imk, PMID:19897652]
+def: "Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+." [PMID:19897652, RHEA:34847]
+xref: EC:1.5.1.50
+xref: MetaCyc:RXN0-6367
+xref: RHEA:34847
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.50
+property_value: skos:exactMatch MetaCyc:RXN0-6367
+property_value: skos:exactMatch RHEA:34847
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: mah
creation_date: 2009-11-23T11:10:17Z
@@ -388512,12 +403196,15 @@
id: GO:0071265
name: L-methionine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid." [GOC:ecd]
+def: "The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid." [GOC:ecd, MetaCyc:Methionine-De-novo-Biosynthesis]
synonym: "L-methionine anabolism" EXACT [GOC:mah]
synonym: "L-methionine biosynthesis" EXACT [GOC:mah]
synonym: "L-methionine formation" EXACT [GOC:mah]
synonym: "L-methionine synthesis" EXACT [GOC:mah]
-is_a: GO:0009086 ! methionine biosynthetic process
+is_a: GO:0000097 ! sulfur amino acid biosynthetic process
+is_a: GO:0006555 ! methionine metabolic process
+is_a: GO:0009067 ! aspartate family amino acid biosynthetic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31068" xsd:anyURI
created_by: mah
creation_date: 2009-12-09T04:28:15Z
@@ -388547,17 +403234,17 @@
[Term]
id: GO:0071268
-name: homocysteine biosynthetic process
+name: obsolete homocysteine biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid." [GOC:ecd, GOC:mah]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid." [GOC:ecd, GOC:mah]
+comment: The reason for obsoletion is that more specific terms were created.
synonym: "homocysteine anabolism" EXACT [GOC:mah]
synonym: "homocysteine biosynthesis" EXACT [GOC:mah]
synonym: "homocysteine formation" EXACT [GOC:mah]
synonym: "homocysteine synthesis" EXACT [GOC:mah]
-is_a: GO:0000097 ! sulfur amino acid biosynthetic process
-is_a: GO:0050667 ! homocysteine metabolic process
-is_a: GO:0170043 ! non-proteinogenic amino acid biosynthetic process
-is_a: GO:1901607 ! alpha-amino acid biosynthetic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31068" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0071269
created_by: mah
creation_date: 2009-12-09T05:32:48Z
@@ -388570,9 +403257,11 @@
synonym: "L-homocysteine biosynthesis" EXACT [GOC:mah]
synonym: "L-homocysteine formation" EXACT [GOC:mah]
synonym: "L-homocysteine synthesis" EXACT [GOC:mah]
+is_a: GO:0000097 ! sulfur amino acid biosynthetic process
is_a: GO:0009070 ! serine family amino acid biosynthetic process
-is_a: GO:0071268 ! homocysteine biosynthetic process
+is_a: GO:0050667 ! homocysteine metabolic process
is_a: GO:0170034 ! L-amino acid biosynthetic process
+is_a: GO:0170043 ! non-proteinogenic amino acid biosynthetic process
created_by: mah
creation_date: 2009-12-09T05:36:37Z
@@ -390348,6 +405037,8 @@
xref: RHEA:62520
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0016434 ! rRNA (cytosine) methyltransferase activity
+property_value: skos:exactMatch RHEA:62520
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2009-12-15T03:46:52Z
@@ -391474,11 +406165,17 @@
id: GO:0071518
name: autoinducer-2 kinase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP." [GOC:imk, PMID:17274596, PMID:20025244]
+def: "Catalysis of the reaction: (S)-4,5-dihydroxypentane-2,3-dione + ATP = (2S)-2-hydroxy-3,4-dioxopentyl phosphate + ADP + H+." [PMID:17274596, PMID:20025244, RHEA:15377]
synonym: "4,5-dihydroxy-pentane-2,3-dione kinase activity" EXACT [CHEBI:29484, GOC:mah]
+xref: EC:2.7.1.189
xref: MetaCyc:RXN0-5461
xref: RHEA:15377
is_a: GO:0016301 ! kinase activity
+is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.189
+property_value: skos:exactMatch MetaCyc:RXN0-5461
+property_value: skos:exactMatch RHEA:15377
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: mah
creation_date: 2010-01-06T05:08:17Z
@@ -391530,6 +406227,9 @@
xref: MetaCyc:URUR-RXN
xref: RHEA:25241
is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
+property_value: skos:exactMatch EC:3.5.3.26
+property_value: skos:exactMatch RHEA:25241
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2010-01-07T01:43:58Z
@@ -391555,7 +406255,6 @@
synonym: "pyrrolysine synthesis" EXACT [GOC:mah]
is_a: GO:0008652 ! amino acid biosynthetic process
is_a: GO:0042398 ! modified amino acid biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0170038 ! proteinogenic amino acid biosynthetic process
created_by: mah
creation_date: 2010-01-07T02:40:24Z
@@ -391975,6 +406674,9 @@
xref: RHEA:60224
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0141052 ! histone H3 demethylase activity
+property_value: skos:exactMatch EC:1.14.11.68
+property_value: skos:exactMatch RHEA:60224
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: mah
creation_date: 2010-01-15T11:33:17Z
@@ -392685,7 +407387,6 @@
synonym: "acyl-CoA formation" EXACT [GOC:mah]
synonym: "acyl-CoA synthesis" EXACT [GOC:mah]
is_a: GO:0006637 ! acyl-CoA metabolic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0044272 ! sulfur compound biosynthetic process
is_a: GO:0072522 ! purine-containing compound biosynthetic process
is_a: GO:1901293 ! nucleoside phosphate biosynthetic process
@@ -394058,7 +408759,6 @@
synonym: "bacterial lipopeptide binding" NARROW [GOC:add]
synonym: "bacterial lipoprotein binding" RELATED [GOC:add]
is_a: GO:0008289 ! lipid binding
-is_a: GO:0033218 ! amide binding
created_by: mah
creation_date: 2010-03-17T02:13:21Z
@@ -394660,10 +409360,17 @@
synonym: "aldehyde decarbonylase activity" EXACT []
synonym: "decarbonylase activity" EXACT [GOC:kad, GOC:mah]
xref: EC:4.1.99.5
+xref: MetaCyc:OCTADECANAL-DECARBONYLASE-RXN
xref: MetaCyc:RXN-13262
xref: RHEA:21440
+xref: RHEA:30415
is_a: GO:0016830 ! carbon-carbon lyase activity
+property_value: skos:exactMatch EC:4.1.99.5
+property_value: skos:exactMatch RHEA:21440
+property_value: skos:narrowMatch MetaCyc:OCTADECANAL-DECARBONYLASE-RXN
+property_value: skos:narrowMatch RHEA:30415
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25056" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2010-04-01T12:02:50Z
@@ -395441,13 +410148,14 @@
[Term]
id: GO:0071854
-name: cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly
+name: obsolete cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly
namespace: biological_process
-def: "The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall." [GOC:mah]
-is_a: GO:0070910 ! cell wall macromolecule catabolic process involved in cell wall disassembly
-intersection_of: GO:0016998 ! cell wall macromolecule catabolic process
-intersection_of: part_of GO:0071853 ! fungal-type cell wall disassembly
-relationship: part_of GO:0071853 ! fungal-type cell wall disassembly
+def: "OBSOLETE. The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall." [GOC:mah]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0016998
+consider: GO:0071853
created_by: mah
creation_date: 2010-09-10T03:12:08Z
@@ -395799,8 +410507,10 @@
xref: EC:2.1.1.244
is_a: GO:0008276 ! protein methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.244
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22688" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23337" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2010-09-13T04:53:57Z
@@ -396545,7 +411255,6 @@
def: "Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes." [GOC:mah]
synonym: "oxidized flavin adenine dinucleotide binding" EXACT [GOC:mah]
synonym: "oxidized flavine-adenine dinucleotide binding" EXACT [GOC:mah]
-xref: Reactome:R-HSA-9854672 "FAD attaches to SDHA"
is_a: GO:0050660 ! flavin adenine dinucleotide binding
created_by: mah
creation_date: 2010-10-07T12:30:28Z
@@ -396584,11 +411293,12 @@
id: GO:0071953
name: elastic fiber
namespace: cellular_component
-def: "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." [GOC:BHF, GOC:mah, PMID:20236620]
+def: "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." [GOC:BHF, PMID:12082143, PMID:16893474, PMID:20236620]
synonym: "elastic fibre" EXACT [GOC:mah]
synonym: "elastin fiber" EXACT [GOC:BHF]
is_a: GO:0099512 ! supramolecular fiber
-relationship: part_of GO:0031012 ! extracellular matrix
+relationship: part_of GO:0140149 ! non-collagenous component of interstitial matrix
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31135" xsd:anyURI
created_by: mah
creation_date: 2010-10-11T11:44:57Z
@@ -396735,6 +411445,8 @@
xref: MetaCyc:RXN0-5122
xref: RHEA:29923
is_a: GO:0008920 ! lipopolysaccharide heptosyltransferase activity
+property_value: skos:exactMatch RHEA:29923
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2010-10-14T05:13:31Z
@@ -396746,6 +411458,8 @@
xref: MetaCyc:RXN0-5127
xref: RHEA:30019
is_a: GO:0008920 ! lipopolysaccharide heptosyltransferase activity
+property_value: skos:exactMatch RHEA:30019
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2010-10-14T05:15:22Z
@@ -397003,7 +411717,7 @@
def: "The directed movement of a phytochelatin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes." [GOC:mah, ISBN:0198506732]
synonym: "cadystin transport" RELATED [GOC:vw, Wikipedia:Phytochelatin#History]
is_a: GO:0015711 ! organic anion transport
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
created_by: mah
creation_date: 2010-10-25T01:57:55Z
@@ -397534,11 +412248,12 @@
[Term]
id: GO:0072042
-name: regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis
+name: obsolete regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron." [GOC:mtg_kidney_jan10]
-is_a: GO:1902460 ! regulation of mesenchymal stem cell proliferation
-relationship: regulates GO:0072090 ! mesenchymal stem cell proliferation involved in nephron morphogenesis
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: mah
creation_date: 2010-01-25T03:11:26Z
@@ -398103,14 +412818,13 @@
[Term]
id: GO:0072096
-name: negative regulation of branch elongation involved in ureteric bud branching
+name: obsolete negative regulation of branch elongation involved in ureteric bud branching
namespace: biological_process
-def: "Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis." [GOC:mtg_kidney_jan10]
-is_a: GO:0048640 ! negative regulation of developmental growth
-is_a: GO:0072095 ! regulation of branch elongation involved in ureteric bud branching
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0060681 ! branch elongation involved in ureteric bud branching
-relationship: negatively_regulates GO:0060681 ! branch elongation involved in ureteric bud branching
+def: "OBSOLETE. Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060681
created_by: mah
creation_date: 2010-02-10T01:52:09Z
@@ -398124,7 +412838,6 @@
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25535" xsd:anyURI
is_obsolete: true
consider: GO:0030509
-consider: GO:0072096
created_by: mah
creation_date: 2010-02-10T02:00:34Z
@@ -399311,14 +414024,15 @@
[Term]
id: GO:0072204
-name: cell-cell signaling involved in metanephros development
+name: obsolete cell-cell signaling involved in metanephros development
namespace: biological_process
-def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10]
+def: "OBSOLETE. Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "cell-cell signalling involved in metanephros development" EXACT [GOC:mah]
-is_a: GO:0060995 ! cell-cell signaling involved in kidney development
-intersection_of: GO:0007267 ! cell-cell signaling
-intersection_of: part_of GO:0001656 ! metanephros development
-relationship: part_of GO:0001656 ! metanephros development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001656
+consider: GO:0007267
created_by: mah
creation_date: 2010-03-18T10:54:36Z
@@ -399937,14 +414651,14 @@
[Term]
id: GO:0072261
-name: metanephric extraglomerular mesangial cell proliferation involved in metanephros development
+name: obsolete metanephric extraglomerular mesangial cell proliferation involved in metanephros development
namespace: biological_process
-def: "The multiplication or reproduction of extraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa." [GOC:mtg_kidney_jan10]
+def: "OBSOLETE. The multiplication or reproduction of extraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "metanephric Goormaghtigh proliferation" RELATED [GOC:mtg_kidney_jan10]
synonym: "metanephric lacis cell proliferation" RELATED [GOC:mtg_kidney_jan10]
-is_a: GO:0072122 ! extraglomerular mesangial cell proliferation
-is_a: GO:0072203 ! cell proliferation involved in metanephros development
-relationship: part_of GO:0072210 ! metanephric nephron development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: mah
creation_date: 2010-03-30T02:14:17Z
@@ -400149,28 +414863,28 @@
[Term]
id: GO:0072280
-name: establishment of planar polarity involved in metanephric nephron morphogenesis
+name: obsolete establishment of planar polarity involved in metanephric nephron morphogenesis
namespace: biological_process
-def: "Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros." [GOC:mtg_kidney_jan10]
+def: "OBSOLETE. Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "establishment of planar cell polarity involved in metanephric nephron morphogenesis" NARROW [GOC:mtg_kidney_jan10]
-is_a: GO:0072046 ! establishment of planar polarity involved in nephron morphogenesis
-intersection_of: GO:0001736 ! establishment of planar polarity
-intersection_of: part_of GO:0072273 ! metanephric nephron morphogenesis
-relationship: part_of GO:0072273 ! metanephric nephron morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001736
+consider: GO:0072273
created_by: mah
creation_date: 2010-04-01T03:17:18Z
[Term]
id: GO:0072281
-name: mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis
+name: obsolete mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis
namespace: biological_process
-def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10]
-is_a: GO:0061208 ! cell differentiation involved in mesonephros development
-is_a: GO:0072037 ! mesenchymal stem cell differentiation involved in nephron morphogenesis
-is_a: GO:0072202 ! cell differentiation involved in metanephros development
-intersection_of: GO:0072497 ! mesenchymal stem cell differentiation
-intersection_of: part_of GO:0072273 ! metanephric nephron morphogenesis
-relationship: part_of GO:0072273 ! metanephric nephron morphogenesis
+def: "OBSOLETE. The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0072273
+consider: GO:0072497
created_by: mah
creation_date: 2010-04-01T03:22:06Z
@@ -400278,27 +414992,27 @@
[Term]
id: GO:0072291
-name: epithelial cell migration involved in metanephric distal tubule morphogenesis
+name: obsolete epithelial cell migration involved in metanephric distal tubule morphogenesis
namespace: biological_process
-def: "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis." [GOC:mtg_kidney_jan10]
-is_a: GO:0072157 ! epithelial cell migration involved in distal tubule morphogenesis
-is_a: GO:0072290 ! epithelial cell migration involved in metanephric nephron tubule morphogenesis
-intersection_of: GO:0010631 ! epithelial cell migration
-intersection_of: part_of GO:0072287 ! metanephric distal tubule morphogenesis
-relationship: part_of GO:0072287 ! metanephric distal tubule morphogenesis
+def: "OBSOLETE. The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0010631
+consider: GO:0072287
created_by: mah
creation_date: 2010-04-09T03:53:37Z
[Term]
id: GO:0072292
-name: epithelial cell migration involved in metanephric proximal tubule morphogenesis
+name: obsolete epithelial cell migration involved in metanephric proximal tubule morphogenesis
namespace: biological_process
-def: "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis." [GOC:mtg_kidney_jan10]
-is_a: GO:0072159 ! epithelial cell migration involved in proximal tubule morphogenesis
-is_a: GO:0072290 ! epithelial cell migration involved in metanephric nephron tubule morphogenesis
-intersection_of: GO:0010631 ! epithelial cell migration
-intersection_of: part_of GO:0072288 ! metanephric proximal tubule morphogenesis
-relationship: part_of GO:0072288 ! metanephric proximal tubule morphogenesis
+def: "OBSOLETE. The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0010631
+consider: GO:0072288
created_by: mah
creation_date: 2010-04-09T03:54:28Z
@@ -400473,18 +415187,14 @@
[Term]
id: GO:0072306
-name: positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
+name: obsolete positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
namespace: biological_process
-def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
+def: "OBSOLETE. Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW []
synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT []
-is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
-is_a: GO:0072304 ! regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
-is_a: GO:1900213 ! positive regulation of mesenchymal cell apoptotic process involved in metanephros development
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
-relationship: positively_regulates GO:0072309 ! mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis
-relationship: positively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: mah
creation_date: 2010-04-09T05:03:41Z
@@ -400841,7 +415551,6 @@
def: "The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." [GOC:mah]
synonym: "cellular lactam metabolic process" EXACT []
synonym: "cellular lactam metabolism" EXACT [GOC:mah]
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0044281 ! small molecule metabolic process
created_by: mah
creation_date: 2010-11-04T04:31:21Z
@@ -400856,7 +415565,7 @@
synonym: "cellular lactam biosynthetic process" EXACT []
synonym: "cellular lactam formation" EXACT [GOC:mah]
synonym: "cellular lactam synthesis" EXACT [GOC:mah]
-is_a: GO:0043604 ! amide biosynthetic process
+is_a: GO:0009058 ! biosynthetic process
is_a: GO:0072338 ! lactam metabolic process
created_by: mah
creation_date: 2010-11-04T04:33:01Z
@@ -400905,13 +415614,15 @@
[Term]
id: GO:0072344
-name: rescue of stalled ribosome
+name: rescue of stalled cytosolic ribosome
namespace: biological_process
-def: "A process of translational elongation that takes place when a ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex." [GOC:jh2, GOC:mah, PMID:18557701, PMID:19170872, PMID:20117091, PMID:20185543]
-is_a: GO:0006414 ! translational elongation
+def: "A process of cytosolic translational elongation that takes place when a cytosolic ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex." [GOC:jh2, GOC:mah, PMID:18557701, PMID:19170872, PMID:20117091, PMID:20185543]
+is_a: GO:0002182 ! cytoplasmic translational elongation
is_a: GO:0032790 ! ribosome disassembly
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22227" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26238" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30547" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31124" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/6481" xsd:anyURI
created_by: mah
creation_date: 2010-11-10T11:54:26Z
@@ -401032,6 +415743,7 @@
synonym: "histone-threonine kinase activity (H3-T3 specific)" EXACT [GOC:mah]
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0140996 ! histone H3 kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: mah
@@ -401212,18 +415924,17 @@
[Term]
id: GO:0072371
-name: obsolete histone H2AS121 kinase activity
+name: histone H2A1S121 kinase activity
namespace: molecular_function
-def: "OBSOLETE. Catalysis of the reaction: histone H2A-serine (position 121) + ATP = histone H2A-phosphoserine (position 121) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 121 of histone H2A." [GOC:mah, PMID:19965387]
-comment: This term was obsoleted because it correponds to the position of histone H2AT120 kinase activity ; GO:1990244 in yeast and Tetrahymena.
+def: "Catalysis of the reaction: histone H2A1-serine (position 121) + ATP = histone H2A-phosphoserine (position 121) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 121 of histone H2A. This serine residue is only present in S. pombe histone H2A1." [GOC:mah, PMID:19965387]
synonym: "histone H2A-S121 kinase activity" EXACT []
synonym: "histone kinase activity (H2A-S121 specific)" EXACT []
synonym: "histone serine kinase activity (H2A-S121 specific)" EXACT [GOC:mah]
synonym: "histone-serine kinase activity (H2A-S121 specific)" EXACT [GOC:mah]
+is_a: GO:0035173 ! histone kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30583" xsd:anyURI
-is_obsolete: true
-replaced_by: GO:1990244
created_by: mah
creation_date: 2010-11-16T03:42:59Z
@@ -401245,7 +415956,16 @@
namespace: molecular_function
def: "Catalysis of the reaction: alpha-carotene + O2 + reduced [NADPH--hemoprotein reductase] = alpha-cryptoxanthin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. Zeinoxanthin may also be used as the substrate, in which case lutein is produced." [EC:1.14.14.158, PMID:8837513]
xref: EC:1.14.14.158
+xref: MetaCyc:RXN-12226
+xref: MetaCyc:RXN-5962
+xref: RHEA:30399
+xref: RHEA:57352
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.158
+property_value: skos:narrowMatch MetaCyc:RXN-12226
+property_value: skos:narrowMatch MetaCyc:RXN-5962
+property_value: skos:narrowMatch RHEA:30399
+property_value: skos:narrowMatch RHEA:57352
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28365" xsd:anyURI
created_by: mah
creation_date: 2010-11-19T03:57:55Z
@@ -402490,6 +417210,7 @@
synonym: "Rho-associated protein kinase activity" EXACT [GOC:ecd]
synonym: "ROCK kinase activity" EXACT [GOC:ecd]
is_a: GO:0004674 ! protein serine/threonine kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: mah
creation_date: 2010-12-22T11:07:29Z
@@ -403167,7 +417888,9 @@
def: "Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+." [GOC:kad, PMID:17074428]
xref: RHEA:69284
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:69284
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21791" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2011-02-07T01:54:21Z
@@ -403204,6 +417927,8 @@
xref: MetaCyc:RXN0-363
xref: RHEA:27994
is_a: GO:0008477 ! purine nucleosidase activity
+property_value: skos:exactMatch RHEA:27994
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2011-02-08T04:38:31Z
@@ -403535,12 +418260,15 @@
[Term]
id: GO:0072655
-name: establishment of protein localization to mitochondrion
+name: obsolete establishment of protein localization to mitochondrion
namespace: biological_process
-def: "The directed movement of a protein to the mitochondrion or a part of the mitochondrion." [GOC:mah]
+def: "OBSOLETE. The directed movement of a protein to the mitochondrion or a part of the mitochondrion." [GOC:mah]
+comment: The reason for obsoletion is that this term was added in error.
synonym: "establishment of protein localisation to mitochondrion" EXACT [GOC:mah]
synonym: "establishment of protein localization in mitochondrion" EXACT []
-is_a: GO:0072594 ! establishment of protein localization to organelle
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30349" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0070585
created_by: mah
creation_date: 2011-02-14T02:28:54Z
@@ -408513,8 +423241,10 @@
xref: MetaCyc:RXN-17884
xref: RHEA:78371
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:78371
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23357" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27135" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0080008
@@ -408553,6 +423283,9 @@
xref: MetaCyc:RXN-9685
xref: RHEA:31987
is_a: GO:0031559 ! oxidosqualene cyclase activity
+property_value: skos:exactMatch EC:5.4.99.57
+property_value: skos:exactMatch RHEA:31987
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0080012
@@ -408567,10 +423300,15 @@
id: GO:0080013
name: (E,E)-geranyllinalool synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: all-trans-geranyl-geranyl diphosphate + H2O = (E,E)-geranyllinalool + diphosphate." [MetaCyc:RXN-10441, PMID:18398052]
+def: "Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = (6E,10E)-geranyllinalool + diphosphate." [PMID:18398052, RHEA:38155]
+xref: EC:4.2.3.144
xref: MetaCyc:RXN-10441
xref: RHEA:38155
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.144
+property_value: skos:exactMatch MetaCyc:RXN-10441
+property_value: skos:exactMatch RHEA:38155
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0080014
@@ -408591,7 +423329,9 @@
xref: RHEA:68636
is_a: GO:0009975 ! cyclase activity
is_a: GO:0010333 ! terpene synthase activity
+property_value: skos:exactMatch RHEA:68636
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28063" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0080016
@@ -408603,6 +423343,9 @@
xref: RHEA:28294
is_a: GO:0009975 ! cyclase activity
is_a: GO:0010334 ! sesquiterpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.57
+property_value: skos:exactMatch RHEA:28294
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0080017
@@ -408614,6 +423357,9 @@
xref: RHEA:31895
is_a: GO:0009975 ! cyclase activity
is_a: GO:0010334 ! sesquiterpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.104
+property_value: skos:exactMatch RHEA:31895
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0080018
@@ -408631,8 +423377,11 @@
synonym: "fatty acyl CoA reductase (alcohol-forming) activity" EXACT []
synonym: "fatty acyl-CoA reductase (alcohol-forming) activity" EXACT [GOC:mah]
synonym: "fatty-acyl-CoA reductase (alcohol-forming) activity" RELATED []
+xref: MetaCyc:RXNQT-4192
xref: RHEA:81751
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch MetaCyc:RXNQT-4192
+property_value: skos:exactMatch RHEA:81751
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24250" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29086" xsd:anyURI
@@ -408644,7 +423393,6 @@
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzyme A." [PMID:18621975]
is_a: GO:0009889 ! regulation of biosynthetic process
is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0042762 ! regulation of sulfur metabolic process
is_a: GO:0051174 ! regulation of phosphorus metabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
@@ -408678,6 +423426,9 @@
xref: MetaCyc:RXN-7699
xref: RHEA:26526
is_a: GO:0018812 ! 3-hydroxyacyl-CoA dehydratase activity
+property_value: skos:exactMatch EC:4.2.1.119
+property_value: skos:exactMatch MetaCyc:RXN-7699
+property_value: skos:exactMatch RHEA:26526
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24738" xsd:anyURI
[Term]
@@ -408749,6 +423500,8 @@
xref: MetaCyc:RXN-10711
xref: RHEA:32919
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch MetaCyc:RXN-10711
+property_value: skos:exactMatch RHEA:32919
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21843" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
@@ -408764,6 +423517,8 @@
xref: MetaCyc:RXNQT-4366
xref: RHEA:33611
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch MetaCyc:RXNQT-4366
+property_value: skos:exactMatch RHEA:33611
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -408777,6 +423532,8 @@
xref: MetaCyc:RXN-10767
xref: RHEA:55372
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch MetaCyc:RXN-10767
+property_value: skos:exactMatch RHEA:55372
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -408861,17 +423618,22 @@
[Term]
id: GO:0080041
-name: ADP-ribose pyrophosphohydrolase activity
+name: ADP-ribose pyrophosphatase activity
namespace: molecular_function
def: "Catalysis of the reaction: ADP-ribose + H2O = AMP + ribose-1-phosphate." [GOC:tb]
-is_a: GO:0019144 ! ADP-sugar diphosphatase activity
+synonym: "ADP-ribose pyrophosphohydrolase activity" EXACT []
+is_a: GO:0019144 ! ADP-sugar pyrophosphatase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31141" xsd:anyURI
[Term]
id: GO:0080042
-name: ADP-glucose pyrophosphohydrolase activity
+name: ADP-glucose pyrophosphatase activity
namespace: molecular_function
def: "Catalysis of the reaction: ADP-glucose + H2O = AMP + glucose-1-phosphate." [GOC:tb]
-is_a: GO:0019144 ! ADP-sugar diphosphatase activity
+synonym: "ADP-glucose pyrophosphohydrolase activity" EXACT []
+is_a: GO:0019144 ! ADP-sugar pyrophosphatase activity
+property_value: term_tracker_item "ADP-glucose diphosphatase activity" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31141" xsd:anyURI
[Term]
id: GO:0080043
@@ -408914,7 +423676,10 @@
xref: MetaCyc:RXNQT-4141
xref: RHEA:27698
is_a: GO:0070568 ! guanylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.69
+property_value: skos:exactMatch RHEA:27698
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23283" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0080048
@@ -408928,7 +423693,10 @@
xref: MetaCyc:RXN-12486
xref: RHEA:30387
is_a: GO:0070568 ! guanylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.78
+property_value: skos:exactMatch RHEA:30387
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23283" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0080049
@@ -408938,7 +423706,9 @@
xref: MetaCyc:RXN-1439
xref: RHEA:47248
is_a: GO:0016632 ! oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor
+property_value: skos:exactMatch RHEA:47248
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25865" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0080050
@@ -409042,6 +423812,7 @@
xref: MetaCyc:RXN-1404
xref: RHEA:45776
is_a: GO:0000257 ! nitrilase activity
+property_value: skos:exactMatch RHEA:45776
created_by: dhl
creation_date: 2009-04-13T03:30:42Z
@@ -409223,7 +423994,9 @@
xref: MetaCyc:RXN-10773
xref: RHEA:30679
is_a: GO:0008422 ! beta-glucosidase activity
+property_value: skos:exactMatch RHEA:30679
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22615" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dhl
creation_date: 2009-04-14T04:07:16Z
@@ -409289,7 +424062,7 @@
name: spermidine hydroxycinnamate conjugate biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of spermidine hydroxycinnamate conjugates." [PMID:19077165]
-is_a: GO:0043604 ! amide biosynthetic process
+is_a: GO:0009058 ! biosynthetic process
created_by: dhl
creation_date: 2009-04-22T03:24:03Z
@@ -409390,6 +424163,9 @@
xref: MetaCyc:RXN-10139
xref: RHEA:27586
is_a: GO:0070529 ! L-tryptophan aminotransferase activity
+property_value: skos:exactMatch EC:2.6.1.99
+property_value: skos:exactMatch RHEA:27586
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dhl
creation_date: 2009-04-23T03:45:23Z
@@ -409402,6 +424178,7 @@
synonym: "L-tyrosine:pyruvate aminotransferase activity" EXACT []
xref: MetaCyc:RXN3O-4157
is_a: GO:0008793 ! aromatic-amino-acid transaminase activity
+property_value: skos:broadMatch EC:2.6.1.58
created_by: dhl
creation_date: 2009-04-23T03:47:53Z
@@ -409612,6 +424389,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: a brassinosteroid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated brassinosteroid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a brassinosteroid acceptor, producing the sulfated brassinosteroid derivative." [PMID:10409637, PMID:17039368]
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:broadMatch EC:2.8.2.-
created_by: dhl
creation_date: 2009-04-27T03:39:36Z
@@ -409680,9 +424458,18 @@
synonym: "jasmonic acid-amino synthetase activity" EXACT []
synonym: "jasmonyl-amino synthetase activity" EXACT []
xref: EC:6.3.2.52
+xref: MetaCyc:RXN-10435
+xref: MetaCyc:RXN-10457
+xref: MetaCyc:RXN-10459
xref: RHEA:55772
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.52
+property_value: skos:exactMatch RHEA:55772
+property_value: skos:narrowMatch MetaCyc:RXN-10435
+property_value: skos:narrowMatch MetaCyc:RXN-10457
+property_value: skos:narrowMatch MetaCyc:RXN-10459
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26578" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dhl
creation_date: 2009-04-28T04:08:35Z
@@ -409761,7 +424548,11 @@
xref: MetaCyc:RXN-10814
xref: RHEA:25152
is_a: GO:0008793 ! aromatic-amino-acid transaminase activity
+property_value: skos:broadMatch EC:2.6.1.5
+property_value: skos:broadMatch EC:2.6.1.57
+property_value: skos:exactMatch RHEA:25152
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31139" xsd:anyURI
created_by: dhl
creation_date: 2009-04-29T03:42:47Z
@@ -409780,8 +424571,15 @@
synonym: "OHJA sulfotransferase activity" EXACT []
xref: EC:2.8.2.39
xref: MetaCyc:RXN-10451
+xref: RHEA:52728
+xref: RHEA:52732
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.39
+property_value: skos:exactMatch MetaCyc:RXN-10451
+property_value: skos:narrowMatch RHEA:52728
+property_value: skos:narrowMatch RHEA:52732
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dhl
creation_date: 2009-04-29T03:47:12Z
@@ -409931,11 +424729,19 @@
id: GO:0080146
name: L-cysteine desulfhydrase activity
namespace: molecular_function
-def: "Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+." [MetaCyc:LCYSDESULF-RXN, PMID:19955263]
+def: "Catalysis of the reaction: L-cysteine + H2O = hydrogen sulfide + pyruvate + NH4+ + H+." [PMID:19955263, RHEA:24931]
+xref: EC:4.4.1.28
xref: MetaCyc:LCYSDESULF-RXN
+xref: Reactome:R-HSA-1614591 "Excess cysteine yields lanthionine and H2S"
+xref: Reactome:R-HSA-1614614 "Cysteine is degraded to serine and H2S"
xref: RHEA:24931
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:broadMatch EC:4.4.1.1
+property_value: skos:exactMatch EC:4.4.1.28
+property_value: skos:exactMatch MetaCyc:LCYSDESULF-RXN
+property_value: skos:exactMatch RHEA:24931
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30959" xsd:anyURI
created_by: dhl
creation_date: 2010-01-27T04:50:43Z
@@ -409979,6 +424785,8 @@
xref: MetaCyc:RXN-6722
xref: RHEA:36099
is_a: GO:0008171 ! O-methyltransferase activity
+property_value: skos:exactMatch RHEA:36099
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dhl
creation_date: 2010-03-26T04:19:39Z
@@ -411286,33 +426094,35 @@
[Term]
id: GO:0086030
-name: adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation
+name: obsolete adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation
namespace: biological_process
-def: "An adrenergic receptor signaling pathway that contributes to a reduction in cardiac muscle contraction. Beta-adrenergic receptor-induced cardiac relaxation is achieved by a GPCR-activated adenylate cyclase generating cAMP; cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the sarcoplasmic reticulum (SR) membrane protein PLB. In its non-phosphorylated state, PLB acts as an inhibitor of the ATPase Ca(2+) pump of the cardiac SR (SERCA2a); inhibition of the pump is relieved upon phosphorylation. The pump removes Ca(2+) from the cytoplasm, thereby preventing cytosolic Ca(2+)-dependent activation of contractile proteins, leading to enhanced muscle relaxation." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:10571541]
+def: "OBSOLETE. An adrenergic receptor signaling pathway that contributes to a reduction in cardiac muscle contraction. Beta-adrenergic receptor-induced cardiac relaxation is achieved by a GPCR-activated adenylate cyclase generating cAMP; cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the sarcoplasmic reticulum (SR) membrane protein PLB. In its non-phosphorylated state, PLB acts as an inhibitor of the ATPase Ca(2+) pump of the cardiac SR (SERCA2a); inhibition of the pump is relieved upon phosphorylation. The pump removes Ca(2+) from the cytoplasm, thereby preventing cytosolic Ca(2+)-dependent activation of contractile proteins, leading to enhanced muscle relaxation." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:10571541]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "adrenergic receptor signaling pathway involved in cardiac muscle relaxation" EXACT []
synonym: "adrenergic receptor signaling pathway involved in cardiac muscle relaxation via activation of AC" RELATED [GOC:mtg_cardiac_conduct_nov11]
synonym: "adrenergic receptor-induced cardiac relaxation" RELATED [PMID:10571541]
synonym: "Gs-coupled adrenergic receptor signaling pathway involved in cardiac muscle relaxation" EXACT [GOC:mtg_cardiac_conduct_nov11]
-is_a: GO:0086023 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
-intersection_of: GO:0071880 ! adenylate cyclase-activating adrenergic receptor signaling pathway
-intersection_of: part_of GO:0055119 ! relaxation of cardiac muscle
-relationship: part_of GO:0055119 ! relaxation of cardiac muscle
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0055119
+consider: GO:0071880
created_by: tb
creation_date: 2011-11-11T02:53:24Z
[Term]
id: GO:0086033
-name: G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate
+name: obsolete G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate
namespace: biological_process
-def: "A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the alpha subunit of a coupled G-protein binding to GTP. This results in the separation of the beta-gamma complex from the alpha subunit. Both the alpha subunit, and the beta-gamma complex can continue to signal to bring about membrane hyperpolarization and a reduction in heart rate." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, Wikipedia:G_protein-gated_ion_channel]
+def: "OBSOLETE. A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the alpha subunit of a coupled G-protein binding to GTP. This results in the separation of the beta-gamma complex from the alpha subunit. Both the alpha subunit, and the beta-gamma complex can continue to signal to bring about membrane hyperpolarization and a reduction in heart rate." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, Wikipedia:G_protein-gated_ion_channel]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate" EXACT []
synonym: "M2 receptor signalling pathway involved in negative regulation of heart rate" EXACT []
synonym: "muscarinic acetylcholine receptor signaling pathway involved in negative regulation of heart rate" EXACT []
synonym: "muscarinic receptor signalling pathway involved in negative regulation of heart rate" EXACT []
-is_a: GO:0086093 ! G protein-coupled acetylcholine receptor signaling pathway involved in heart process
-intersection_of: GO:0007213 ! G protein-coupled acetylcholine receptor signaling pathway
-intersection_of: part_of GO:0010459 ! negative regulation of heart rate
-relationship: part_of GO:0003063 ! negative regulation of heart rate by acetylcholine
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007213
+consider: GO:0010459
created_by: tb
creation_date: 2011-11-11T03:11:58Z
@@ -411327,13 +426137,13 @@
[Term]
id: GO:0086037
-name: P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential
+name: obsolete P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential
namespace: molecular_function
-def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in), that contributes to regulating the membrane potential of a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
-is_a: GO:0005391 ! P-type sodium:potassium-exchanging transporter activity
-intersection_of: GO:0005391 ! P-type sodium:potassium-exchanging transporter activity
-intersection_of: part_of GO:0086036 ! regulation of cardiac muscle cell membrane potential
-relationship: part_of GO:0086036 ! regulation of cardiac muscle cell membrane potential
+def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in), that contributes to regulating the membrane potential of a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
+comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31205" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0005391
created_by: tb
creation_date: 2011-11-11T03:33:44Z
@@ -411364,14 +426174,15 @@
[Term]
id: GO:0086040
-name: sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential
+name: obsolete sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential
namespace: molecular_function
-def: "Enables the transfer of a solute or solutes from one side of a cardiac muscle cell membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). This transfer contributes to the regulation of the cardiac muscle cell plasma membrane potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
+def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a cardiac muscle cell membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). This transfer contributes to the regulation of the cardiac muscle cell plasma membrane potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "sodium:hydrogen antiporter activity involved in regulation of cardiac muscle cell membrane potential" EXACT []
-is_a: GO:0015385 ! sodium:proton antiporter activity
-intersection_of: GO:0015385 ! sodium:proton antiporter activity
-intersection_of: part_of GO:0086036 ! regulation of cardiac muscle cell membrane potential
-relationship: part_of GO:0086036 ! regulation of cardiac muscle cell membrane potential
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0015385
+consider: GO:0086036
created_by: tb
creation_date: 2011-11-11T03:33:44Z
@@ -411594,13 +426405,14 @@
[Term]
id: GO:0086058
-name: voltage-gated calcium channel activity involved in Purkinje myocyte cell action potential
+name: obsolete voltage-gated calcium channel activity involved in Purkinje myocyte cell action potential
namespace: molecular_function
-def: "Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an Purkinje myocyte cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
-is_a: GO:0086007 ! voltage-gated calcium channel activity involved in cardiac muscle cell action potential
-intersection_of: GO:0005245 ! voltage-gated calcium channel activity
-intersection_of: part_of GO:0086017 ! Purkinje myocyte action potential
-relationship: part_of GO:0086047 ! membrane depolarization during Purkinje myocyte cell action potential
+def: "OBSOLETE. Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an Purkinje myocyte cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0005245
+consider: GO:0086017
created_by: dph
creation_date: 2011-11-17T12:35:02Z
@@ -411884,15 +426696,16 @@
[Term]
id: GO:0086081
-name: cell adhesive protein binding involved in atrial cardiac muscle cell-AV node cell communication
+name: obsolete cell adhesive protein binding involved in atrial cardiac muscle cell-AV node cell communication
namespace: molecular_function
-def: "Binding to a protein or protein complex that results in the connection of an atrial cardiomyocyte with an AV node cell and contributes to the communication between the two cells." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
+def: "OBSOLETE. Binding to a protein or protein complex that results in the connection of an atrial cardiomyocyte with an AV node cell and contributes to the communication between the two cells." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "cell adhesive protein binding involved in atrial cardiomyocyte-atrioventricular node cell communication" EXACT []
synonym: "cell adhesive protein binding involved in atrial cardiomyocyte-AV node cell communication" EXACT []
-is_a: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion
-intersection_of: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion
-intersection_of: part_of GO:0086071 ! atrial cardiac muscle cell-AV node cell adhesion involved in cell communication
-relationship: part_of GO:0086071 ! atrial cardiac muscle cell-AV node cell adhesion involved in cell communication
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0086071
+consider: GO:0086080
created_by: dph
creation_date: 2011-11-22T11:00:47Z
@@ -411923,38 +426736,41 @@
[Term]
id: GO:0086084
-name: cell adhesive protein binding involved in Purkinje myocyte-ventricular cardiac muscle cell communication
+name: obsolete cell adhesive protein binding involved in Purkinje myocyte-ventricular cardiac muscle cell communication
namespace: molecular_function
-def: "Binding to a protein or protein complex that results in the connection of a Purkinje myocyte with an ventricular cardiac muscle cell and contributes to the communication between the two cells." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
-is_a: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion
-intersection_of: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion
-intersection_of: part_of GO:0086074 ! Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication
-relationship: part_of GO:0086074 ! Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication
+def: "OBSOLETE. Binding to a protein or protein complex that results in the connection of a Purkinje myocyte with an ventricular cardiac muscle cell and contributes to the communication between the two cells." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0086074
+consider: GO:0086080
created_by: dph
creation_date: 2011-11-22T11:13:16Z
[Term]
id: GO:0086085
-name: cell adhesive protein binding involved in SA cardiac muscle cell-atrial cardiac muscle cell communication
+name: obsolete cell adhesive protein binding involved in SA cardiac muscle cell-atrial cardiac muscle cell communication
namespace: molecular_function
-def: "Binding to a protein or protein complex that results in the connection of an SA cardiomyocyte with an atrial cardiomyocyte and contributes to the communication between the two cells." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
+def: "OBSOLETE. Binding to a protein or protein complex that results in the connection of an SA cardiomyocyte with an atrial cardiomyocyte and contributes to the communication between the two cells." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "cell adhesive protein binding involved in SA cardiomyocyte-atrial cardiomyocyte communication" EXACT []
-is_a: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion
-intersection_of: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion
-intersection_of: part_of GO:0086022 ! SA node cell-atrial cardiac muscle cell adhesion involved in cell communication
-relationship: part_of GO:0086022 ! SA node cell-atrial cardiac muscle cell adhesion involved in cell communication
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0086022
+consider: GO:0086080
created_by: dph
creation_date: 2011-11-22T11:15:07Z
[Term]
id: GO:0086086
-name: voltage-gated potassium channel activity involved in AV node cell action potential repolarization
+name: obsolete voltage-gated potassium channel activity involved in AV node cell action potential repolarization
namespace: molecular_function
-def: "Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
+def: "OBSOLETE. Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "voltage-gated potassium channel activity involved in atrioventricular node cardiac muscle cell action potential" EXACT []
synonym: "voltage-gated potassium channel activity involved in AV node cardiac muscle cell action potential repolarization" EXACT []
-is_a: GO:0086008 ! voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
-relationship: part_of GO:0086049 ! membrane repolarization during AV node cell action potential
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2011-11-22T01:26:32Z
@@ -411970,11 +426786,12 @@
[Term]
id: GO:0086088
-name: voltage-gated potassium channel activity involved in Purkinje myocyte action potential repolarization
+name: obsolete voltage-gated potassium channel activity involved in Purkinje myocyte action potential repolarization
namespace: molecular_function
-def: "Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
-is_a: GO:0086008 ! voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
-relationship: part_of GO:0086051 ! membrane repolarization during Purkinje myocyte action potential
+def: "OBSOLETE. Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: dph
creation_date: 2011-11-22T01:32:02Z
@@ -412109,18 +426926,19 @@
[Term]
id: GO:0086099
-name: phospholipase C-activating angiotensin-activated signaling pathway involved in heart process
+name: obsolete phospholipase C-activating angiotensin-activated signaling pathway involved in heart process
namespace: biological_process
-def: "An angiotensin-mediated signaling pathway that contributes to a circulatory system process carried out by the heart, where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:17376402]
+def: "OBSOLETE. An angiotensin-mediated signaling pathway that contributes to a circulatory system process carried out by the heart, where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:17376402]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "angiotensin receptor signaling pathway via activation of phospholipase C involved in heart process" EXACT [GOC:bf]
synonym: "cardiac angiotensin receptor signaling pathway via activation of PLC" EXACT [GOC:bf]
synonym: "Gq-coupled angiotensin receptor signaling pathway involved in heart process" EXACT [PMID:17376402]
synonym: "phospholipase C-activating angiotensin-mediated signaling pathway involved in heart process" RELATED []
synonym: "PLC-activating angiotensin receptor signaling pathway involved in heart process" EXACT [GOC:bf]
-is_a: GO:0086097 ! phospholipase C-activating angiotensin-activated signaling pathway
-is_a: GO:0086098 ! angiotensin-activated signaling pathway involved in heart process
-intersection_of: GO:0086097 ! phospholipase C-activating angiotensin-activated signaling pathway
-intersection_of: part_of GO:0003015 ! heart process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003015
+consider: GO:0086097
created_by: bf
[Term]
@@ -412208,6 +427026,8 @@
xref: EC:2.7.8.31
xref: RHEA:28126
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.31
+property_value: skos:exactMatch RHEA:28126
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
[Term]
@@ -412293,6 +427113,9 @@
xref: EC:1.1.1.336
xref: RHEA:25780
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.336
+property_value: skos:exactMatch RHEA:25780
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0089715
@@ -412306,7 +427129,9 @@
xref: MetaCyc:RXN0-7114
xref: RHEA:70027
is_a: GO:0016426 ! tRNA (adenine) methyltransferase activity
+property_value: skos:exactMatch RHEA:70027
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25829" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0089716
@@ -412673,10 +427498,6 @@
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion." [GOC:dph, GOC:tb]
is_a: GO:0010969 ! regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
-is_a: GO:0060239 ! positive regulation of signal transduction involved in conjugation with cellular fusion
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0000750 ! pheromone-dependent signal transduction involved in conjugation with cellular fusion
-relationship: positively_regulates GO:0000750 ! pheromone-dependent signal transduction involved in conjugation with cellular fusion
created_by: tb
creation_date: 2009-08-03T10:25:27Z
@@ -414072,29 +428893,30 @@
[Term]
id: GO:0090151
-name: establishment of protein localization to mitochondrial membrane
+name: obsolete establishment of protein localization to mitochondrial membrane
namespace: biological_process
-def: "The directed movement of a protein to a specific location in the mitochondrial membrane." [GOC:ascb_2009, GOC:dph, GOC:tb]
+def: "OBSOLETE. The directed movement of a protein to a specific location in the mitochondrial membrane." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: The reason for obsoletion is that this term was added in error.
synonym: "establishment of protein localisation in mitochondrial membrane" EXACT [GOC:mah]
synonym: "establishment of protein localization in mitochondrial membrane" EXACT []
-is_a: GO:0007006 ! mitochondrial membrane organization
-is_a: GO:0051649 ! establishment of localization in cell
-is_a: GO:0072655 ! establishment of protein localization to mitochondrion
-is_a: GO:0090150 ! establishment of protein localization to membrane
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30349" xsd:anyURI
+is_obsolete: true
+consider: GO:0045039
+consider: GO:0045040
created_by: tb
creation_date: 2009-12-08T03:18:51Z
[Term]
id: GO:0090152
-name: establishment of protein localization to mitochondrial membrane involved in mitochondrial fission
+name: obsolete establishment of protein localization to mitochondrial membrane involved in mitochondrial fission
namespace: biological_process
-def: "The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission." [GOC:ascb_2009, GOC:dph, GOC:tb]
+def: "OBSOLETE. The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: The reason for obsoletion is that this term was added in error.
synonym: "establishment of protein localisation in mitochondrial membrane involved in mitochondrial fission" EXACT [GOC:mah]
synonym: "establishment of protein localization in mitochondrial membrane involved in mitochondrial fission" EXACT []
-is_a: GO:0090151 ! establishment of protein localization to mitochondrial membrane
-intersection_of: GO:0090151 ! establishment of protein localization to mitochondrial membrane
-intersection_of: part_of GO:0000266 ! mitochondrial fission
-relationship: part_of GO:0000266 ! mitochondrial fission
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30349" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0070585
created_by: tb
creation_date: 2009-12-08T03:18:51Z
@@ -414106,7 +428928,6 @@
is_a: GO:0010556 ! regulation of macromolecule biosynthetic process
is_a: GO:0044087 ! regulation of cellular component biogenesis
is_a: GO:0046890 ! regulation of lipid biosynthetic process
-is_a: GO:1905038 ! regulation of membrane lipid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030148 ! sphingolipid biosynthetic process
relationship: regulates GO:0030148 ! sphingolipid biosynthetic process
@@ -414165,14 +428986,13 @@
[Term]
id: GO:0090159
-name: sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization
+name: obsolete sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of sphingolipids that contributes to endoplasmic reticulum membrane organization." [GOC:ascb_2009, GOC:dph, GOC:tb]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of sphingolipids that contributes to endoplasmic reticulum membrane organization." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM.
synonym: "sphingolipid biosynthesis involved in endoplasmic reticulum membrane organisation" EXACT [GOC:mah]
-is_a: GO:0030148 ! sphingolipid biosynthetic process
-intersection_of: GO:0030148 ! sphingolipid biosynthetic process
-intersection_of: part_of GO:0090158 ! endoplasmic reticulum membrane organization
-relationship: part_of GO:0090158 ! endoplasmic reticulum membrane organization
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31228" xsd:anyURI
+is_obsolete: true
created_by: tb
creation_date: 2009-12-08T08:31:13Z
@@ -415261,13 +430081,13 @@
[Term]
id: GO:0090250
-name: cell-cell adhesion involved in establishment of planar polarity
+name: obsolete cell-cell adhesion involved in establishment of planar polarity
namespace: biological_process
-def: "The attachment of one cell to another cell via adhesion molecules that contributes to the establishment of planar cell polarity." [GOC:ascb_2009, GOC:dph, GOC:tb]
-is_a: GO:0098609 ! cell-cell adhesion
-intersection_of: GO:0098609 ! cell-cell adhesion
-intersection_of: part_of GO:0001736 ! establishment of planar polarity
-relationship: part_of GO:0001736 ! establishment of planar polarity
+def: "OBSOLETE. The attachment of one cell to another cell via adhesion molecules that contributes to the establishment of planar cell polarity." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001736
created_by: tb
creation_date: 2010-01-22T11:28:03Z
@@ -415286,13 +430106,14 @@
[Term]
id: GO:0090252
-name: epithelium migration involved in imaginal disc-derived wing morphogenesis
+name: obsolete epithelium migration involved in imaginal disc-derived wing morphogenesis
namespace: biological_process
-def: "The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis." [GOC:ascb_2009, GOC:dph, GOC:tb]
-is_a: GO:0090132 ! epithelium migration
-intersection_of: GO:0090132 ! epithelium migration
-intersection_of: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis
-relationship: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis
+def: "OBSOLETE. The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis." [GOC:ascb_2009, GOC:dph, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007476
+consider: GO:0090132
created_by: tb
creation_date: 2010-01-22T11:40:46Z
@@ -417047,13 +431868,14 @@
[Term]
id: GO:0090388
-name: phagosome-lysosome docking involved in apoptotic cell clearance
+name: obsolete phagosome-lysosome docking involved in apoptotic cell clearance
namespace: biological_process
-def: "The initial attachment of a phagosome membrane to a lysosome membrane that occurs as a part of apoptotic cell clearance. Docking requires only that the proteins come close enough to interact and adhere." [GOC:kmv, GOC:tb]
-is_a: GO:0090384 ! phagosome-lysosome docking
-intersection_of: GO:0090384 ! phagosome-lysosome docking
-intersection_of: part_of GO:0090387 ! phagolysosome assembly involved in apoptotic cell clearance
-relationship: part_of GO:0090387 ! phagolysosome assembly involved in apoptotic cell clearance
+def: "OBSOLETE. The initial attachment of a phagosome membrane to a lysosome membrane that occurs as a part of apoptotic cell clearance. Docking requires only that the proteins come close enough to interact and adhere." [GOC:kmv, GOC:tb]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0090384
+consider: GO:0090387
created_by: tb
creation_date: 2010-10-27T10:57:39Z
@@ -417282,7 +432104,10 @@
xref: MetaCyc:RXN-12359
xref: RHEA:32139
is_a: GO:0016405 ! CoA-ligase activity
+property_value: skos:exactMatch EC:6.2.1.76
+property_value: skos:exactMatch RHEA:32139
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24054" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: tb
creation_date: 2011-06-10T01:51:16Z
@@ -417346,7 +432171,10 @@
xref: EC:1.17.7.2
xref: RHEA:53544
is_a: GO:0052592 ! oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.17.7.2
+property_value: skos:exactMatch RHEA:53544
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27696" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: tb
creation_date: 2011-10-03T12:08:27Z
@@ -417355,7 +432183,7 @@
name: nicotinate transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of nicotinate from one side of a membrane to the other." [GOC:tb]
-xref: Reactome:R-HSA-8869603 "SLC22A13 exchanges extracellular NCA for cytosolic urate"
+xref: Reactome:R-HSA-8869603 "SLC22A13 transports NCA from extracellular region to cytosol"
is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity
relationship: part_of GO:2001142 ! nicotinate transport
created_by: tb
@@ -417549,7 +432377,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA." [GOC:al, PMID:18071249]
synonym: "palmitoyl-CoA synthetase activity" EXACT []
-xref: Reactome:R-HSA-434382 "ACSL3,4 ligates coenzyme A (CoA-SH) to a long chain fatty acid yielding fatty acyl-coenzyme A"
+xref: Reactome:R-HSA-434382 "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell"
is_a: GO:0004467 ! long-chain fatty acid-CoA ligase activity
created_by: tb
creation_date: 2012-07-25T03:31:31Z
@@ -417598,9 +432426,16 @@
id: GO:0090438
name: camelliol C synthase activity
namespace: molecular_function
-def: "Catalyzes the reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = camelliol C." [GOC:tb, PMID:17985917]
+def: "Catalyzes the reaction: (S)-2,3-epoxysqualene = camelliol C." [PMID:17985917, RHEA:31011]
synonym: "(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, camelliol-C-forming)" EXACT []
+xref: EC:5.4.99.38
+xref: MetaCyc:RXN-12330
+xref: RHEA:31011
is_a: GO:0016866 ! intramolecular transferase activity
+property_value: skos:exactMatch EC:5.4.99.38
+property_value: skos:exactMatch MetaCyc:RXN-12330
+property_value: skos:exactMatch RHEA:31011
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: tb
creation_date: 2012-08-08T15:41:45Z
@@ -417611,6 +432446,7 @@
def: "Catalyzes the reaction: 7-hydroxylauroyl-CoA + 3 malonyl-CoA + 2 H+ = 2-(8-hydroxy-2-oxotridecyl)-6-oxopyran-4-olate + 3 CO2 + 4 coenzyme A." [MetaCyc:RXN-16407, PMID:21193570]
xref: MetaCyc:RXN-16407
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch MetaCyc:RXN-16407
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
created_by: tb
@@ -417710,6 +432546,9 @@
xref: EC:2.3.1.198
xref: RHEA:33559
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.198
+property_value: skos:exactMatch RHEA:33559
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: tb
creation_date: 2012-08-31T09:23:12Z
@@ -417897,6 +432736,9 @@
xref: MetaCyc:RXN-11354
xref: RHEA:30967
is_a: GO:0016859 ! cis-trans isomerase activity
+property_value: skos:exactMatch EC:5.2.1.12
+property_value: skos:exactMatch MetaCyc:RXN-11354
+property_value: skos:exactMatch RHEA:30967
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
created_by: tb
creation_date: 2012-09-24T16:29:49Z
@@ -418009,7 +432851,10 @@
xref: EC:2.1.1.386
xref: RHEA:37887
is_a: GO:0062105 ! RNA 2'-O-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.386
+property_value: skos:exactMatch RHEA:37887
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24842" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: tb
creation_date: 2012-10-15T16:32:49Z
@@ -418046,7 +432891,10 @@
xref: KEGG_REACTION:R08160
xref: RHEA:33279
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.156
+property_value: skos:exactMatch RHEA:33279
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: tb
creation_date: 2012-10-16T16:22:19Z
@@ -418159,6 +433007,9 @@
xref: MetaCyc:RXN-11483
xref: RHEA:42700
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.85
+property_value: skos:exactMatch MetaCyc:RXN-11483
+property_value: skos:exactMatch RHEA:42700
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
created_by: tb
creation_date: 2012-10-19T12:10:01Z
@@ -418416,6 +433267,7 @@
synonym: "cytochrome-b5 reductase activity" BROAD []
xref: RHEA:64576
is_a: GO:0004128 ! cytochrome-b5 reductase activity, acting on NAD(P)H
+property_value: skos:exactMatch RHEA:64576
created_by: tb
creation_date: 2013-01-11T12:21:41Z
@@ -418436,6 +433288,8 @@
xref: MetaCyc:CYTOCHROME-B5-REDUCTASE-RXN
xref: RHEA:46680
is_a: GO:0004128 ! cytochrome-b5 reductase activity, acting on NAD(P)H
+property_value: skos:exactMatch EC:1.6.2.2
+property_value: skos:exactMatch RHEA:46680
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
created_by: tb
creation_date: 2013-01-11T12:21:50Z
@@ -418696,6 +433550,9 @@
xref: RHEA:38583
is_a: GO:0008525 ! phosphatidylcholine transporter activity
is_a: GO:0140328 ! floppase activity
+property_value: skos:broadMatch RHEA:66132
+property_value: skos:exactMatch RHEA:38583
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: tb
creation_date: 2013-10-24T16:07:20Z
@@ -418710,6 +433567,7 @@
synonym: "phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaflet)" EXACT []
synonym: "phosphatidylethanolamine-translocating ATPase activity" RELATED []
is_a: GO:0140333 ! glycerophospholipid flippase activity
+property_value: skos:broadMatch RHEA:66132
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28937" xsd:anyURI
created_by: tb
creation_date: 2013-10-24T16:07:20Z
@@ -418726,6 +433584,9 @@
xref: RHEA:38567
is_a: GO:0005548 ! phospholipid transporter activity
is_a: GO:0140328 ! floppase activity
+property_value: skos:broadMatch RHEA:66132
+property_value: skos:exactMatch RHEA:38567
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: tb
creation_date: 2013-10-24T16:07:20Z
@@ -418766,7 +433627,10 @@
xref: Reactome:R-HSA-5358494 "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2"
xref: RHEA:36783
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.108
+property_value: skos:exactMatch RHEA:36783
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22469" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: tb
creation_date: 2014-03-27T14:58:50Z
@@ -419086,7 +433950,7 @@
[Term]
id: GO:0090595
-name: L-lysine N6-acetyltransferase
+name: L-lysine N6-acetyltransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: acetyl-CoA + L-lysine = CoA + H+ + N(6)-acetyl-L-lysine." [RHEA:69476]
synonym: "acetyl-CoA:L-lysine N6-acetyltransferase" EXACT []
@@ -419094,6 +433958,9 @@
xref: MetaCyc:LYSACET-RXN
xref: RHEA:69476
is_a: GO:0140085 ! L-amino-acid N-acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.306
+property_value: skos:exactMatch MetaCyc:LYSACET-RXN
+property_value: skos:exactMatch RHEA:69476
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
created_by: tb
creation_date: 2014-08-21T17:19:06Z
@@ -419235,7 +434102,7 @@
name: ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination." [PMID:22547407]
-is_a: GO:0051603 ! proteolysis involved in protein catabolic process
+is_a: GO:0030163 ! protein catabolic process
relationship: has_part GO:0007039 ! protein catabolic process in the vacuole
relationship: has_part GO:0071985 ! multivesicular body sorting pathway
created_by: tb
@@ -419251,7 +434118,10 @@
xref: RHEA:22908
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.46
+property_value: skos:exactMatch RHEA:22908
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19833#top" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: tb
creation_date: 2014-10-23T15:46:42Z
@@ -419264,6 +434134,8 @@
xref: RHEA:42892
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.41
+property_value: skos:exactMatch RHEA:42892
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19833#top" xsd:anyURI
created_by: tb
creation_date: 2014-10-23T15:59:38Z
@@ -419277,7 +434149,10 @@
xref: RHEA:25025
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.4.31
+property_value: skos:exactMatch RHEA:25025
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19833#top" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: tb
creation_date: 2014-10-23T15:59:38Z
@@ -420247,6 +435122,9 @@
xref: MetaCyc:RXN-10067
xref: RHEA:40955
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.99
+property_value: skos:exactMatch MetaCyc:RXN-10067
+property_value: skos:exactMatch RHEA:40955
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
created_by: tb
creation_date: 2016-10-21T15:59:34Z
@@ -420261,7 +435139,10 @@
xref: MetaCyc:RXN0-5187
xref: RHEA:35587
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.102
+property_value: skos:exactMatch RHEA:35587
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27934" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: tb
creation_date: 2016-10-21T16:27:34Z
@@ -420484,15 +435365,15 @@
id: GO:0090733
name: tenascin complex
namespace: cellular_component
-def: "A extracellular matrix complex involved in cell adhesion and cell migration. Typically homotrimeric or homohexameric. In mammals, four complexes exist: Tenascin-C, Tenascin-N (also known as Tenascin-W), Tenascin-X and Tenascin-R." [GOC:bhm, PMID:11731446, PMID:12845616, PMID:17909022, PMID:23658023]
-comment: An example is Tenascin-N (Q9UQP3) in PMID:17909022 (IDA).
+def: "A homotrimeric or homohexameric extracellular matrix complex involved in cell adhesion and cell migration. In mammals, four complexes exist: Tenascin-C, Tenascin-N (also known as Tenascin-W), Tenascin-X and Tenascin-R." [PMID:10842355, PMID:11731446, PMID:12845616, PMID:17909022, PMID:23658023]
synonym: "Tenascin-C" NARROW []
synonym: "Tenascin-N" NARROW []
synonym: "Tenascin-R" NARROW []
synonym: "Tenascin-W" NARROW []
synonym: "Tenascin-X" NARROW []
is_a: GO:0098637 ! protein complex involved in cell-matrix adhesion
-relationship: part_of GO:0031012 ! extracellular matrix
+relationship: part_of GO:0140149 ! non-collagenous component of interstitial matrix
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31064" xsd:anyURI
created_by: tb
creation_date: 2017-02-01T16:29:55Z
@@ -420589,7 +435470,6 @@
name: ceramide binding
namespace: molecular_function
def: "Binding to a ceramide, a class of lipids composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes." [GOC:sart]
-is_a: GO:0033218 ! amide binding
is_a: GO:0046625 ! sphingolipid binding
created_by: pr
creation_date: 2011-03-09T11:34:09Z
@@ -420658,6 +435538,8 @@
xref: MetaCyc:RXN-8620
xref: RHEA:13545
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:13545
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2011-03-16T04:37:20Z
@@ -420843,6 +435725,8 @@
def: "Catalysis of the reaction: D-fructose-6-phosphate = dihydroxyacetone + D-glyceraldehyde-3-phosphate." [GOC:imk, PMID:11120740, PMID:21290439]
xref: RHEA:28002
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch RHEA:28002
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2011-03-29T04:54:05Z
@@ -421184,6 +436068,7 @@
synonym: "L-glutamate formation" EXACT []
synonym: "L-glutamate synthesis" EXACT []
is_a: GO:0006537 ! glutamate biosynthetic process
+property_value: skos:broadMatch MetaCyc:PWY-5505
created_by: pr
creation_date: 2011-05-24T04:30:38Z
@@ -422234,6 +437119,7 @@
comment: The reason for obsoletion is that this term represents a GO-CAM model.
synonym: "caspase activity" BROAD []
synonym: "metacaspase activity" NARROW [GOC:mtg_apoptosis]
+xref: Reactome:R-HSA-6800797 "The PIDDosome activates CASP2"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28468" xsd:anyURI
is_obsolete: true
replaced_by: GO:0004197
@@ -422295,6 +437181,7 @@
namespace: molecular_function
def: "OBSOLETE. Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure." [GOC:sjw, PMID:7583672]
comment: The reason for obsoletion is that this term was an unnecessary grouping term.
+xref: Reactome:R-HSA-1497796 "BH2 binding can lead to eNOS uncoupling"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29143" xsd:anyURI
is_obsolete: true
created_by: pr
@@ -423407,8 +438294,11 @@
comment: This enzymatic activity is usually negligible, but may become prominent when phenylalanine levels are abnormally high as in the human disease phenylketonuria (PKU).
xref: RHEA:38351
is_a: GO:0140175 ! (2R)-2-hydroxyacid dehydrogenase (NAD+) activity
+property_value: skos:broadMatch EC:1.1.1.110
+property_value: skos:exactMatch RHEA:38351
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2012-03-07T11:39:39Z
@@ -423421,6 +438311,8 @@
xref: Reactome:R-HSA-2161567 "LTB4 is oxidised to 12-oxoLTB4 by PTGR1"
xref: RHEA:50608
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch RHEA:50608
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2012-03-07T02:07:41Z
@@ -423435,6 +438327,8 @@
xref: RHEA:48668
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+property_value: skos:exactMatch RHEA:48668
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2012-03-07T03:37:53Z
@@ -423447,6 +438341,8 @@
xref: Reactome:R-HSA-2161979 "20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH"
xref: RHEA:48672
is_a: GO:0004497 ! monooxygenase activity
+property_value: skos:exactMatch RHEA:48672
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2012-03-07T03:40:05Z
@@ -423456,6 +438352,7 @@
namespace: molecular_function
def: "OBSOLETE. Catalysis of the reaction: leukotriene A4 = eoxin A4." [GOC:mw, PMID:18184802, PMID:18647347]
comment: The reason for obsoletion is that this term is equivalent to leukotriene-C4 synthase activity.
+xref: Reactome:R-HSA-2162019 "LTA4 is converted to EXA4 by ALOX15"
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29695" xsd:anyURI
is_obsolete: true
replaced_by: GO:0004464
@@ -423528,6 +438425,9 @@
xref: KEGG_REACTION:R09838
xref: RHEA:32171
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.149
+property_value: skos:exactMatch RHEA:32171
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2012-03-13T09:22:47Z
@@ -423569,8 +438469,11 @@
xref: Reactome:R-HSA-2162253 "PDSS1,2 ligates FPP to IPPP"
xref: RHEA:27802
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.91
+property_value: skos:exactMatch RHEA:27802
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2012-03-20T01:00:23Z
@@ -424560,38 +439463,43 @@
synonym: "protein O-GlcNAc transferase activity" EXACT []
synonym: "UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase" EXACT []
xref: EC:2.4.1.255
-xref: Reactome:R-HSA-8879117 "POMGNT2 transfers GlcNAc to Man-DAG1"
xref: Reactome:R-HSA-9687828 "O-GlcNAcylation of RIPK3 (TLR4 signaling)"
+xref: RHEA:48904
+xref: RHEA:48908
is_a: GO:0008375 ! acetylglucosaminyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.4.1.255
+property_value: skos:narrowMatch RHEA:48904
+property_value: skos:narrowMatch RHEA:48908
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23320" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2012-07-24T01:46:51Z
[Term]
id: GO:0097364
-name: stretch-activated, monoatomic cation-selective, calcium channel activity involved in regulation of action potential
+name: obsolete stretch-activated, monoatomic cation-selective, calcium channel activity involved in regulation of action potential
namespace: molecular_function
-def: "Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:21290758]
+def: "OBSOLETE. Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:21290758]
+comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
synonym: "stretch-activated, cation-selective, calcium channel activity involved in regulation of action potential" BROAD []
-is_a: GO:0015275 ! stretch-activated, monoatomic cation-selective, calcium channel activity
-intersection_of: GO:0015275 ! stretch-activated, monoatomic cation-selective, calcium channel activity
-intersection_of: regulates GO:0001508 ! action potential
-relationship: regulates GO:0001508 ! action potential
-property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31205" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0015275
created_by: pr
creation_date: 2012-07-25T04:08:33Z
[Term]
id: GO:0097365
-name: stretch-activated, monoatomic cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential
+name: obsolete stretch-activated, monoatomic cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential
namespace: molecular_function
-def: "Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:21290758]
+def: "OBSOLETE. OBSOLETE. Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:21290758]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "stretch-activated, cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential" BROAD []
-is_a: GO:0097364 ! stretch-activated, monoatomic cation-selective, calcium channel activity involved in regulation of action potential
-intersection_of: GO:0015275 ! stretch-activated, monoatomic cation-selective, calcium channel activity
-intersection_of: regulates GO:0086001 ! cardiac muscle cell action potential
-relationship: regulates GO:0086001 ! cardiac muscle cell action potential
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31205" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0015275
created_by: pr
creation_date: 2012-07-26T02:39:10Z
@@ -424662,6 +439570,7 @@
synonym: "NAD-dependent histone H3K18 deacetylase activity" EXACT []
is_a: GO:0017136 ! histone deacetylase activity, NAD-dependent
is_a: GO:0141050 ! histone H3K deacetylase activity
+property_value: skos:broadMatch EC:2.3.1.286
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22836" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pr
@@ -424776,6 +439685,8 @@
xref: Reactome:R-HSA-2509793 "NUDT16 hydrolyses dIDP to dIMP"
xref: RHEA:35211
is_a: GO:0017110 ! nucleoside diphosphate phosphatase activity
+property_value: skos:exactMatch RHEA:35211
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2012-10-11T16:04:40Z
@@ -425325,7 +440236,9 @@
xref: RHEA:29303
is_a: GO:0015141 ! succinate transmembrane transporter activity
is_a: GO:0015295 ! solute:proton symporter activity
+property_value: skos:exactMatch RHEA:29303
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2012-11-26T18:19:42Z
@@ -425861,7 +440774,7 @@
name: multivesicular body, internal vesicle
namespace: cellular_component
def: "A membrane-bounded vesicle wholly contained within a multivesicular body." [GOC:pde, PMID:21183070]
-is_a: GO:0031410 ! cytoplasmic vesicle
+is_a: GO:0160313 ! endosomal intralumenal vesicle
relationship: part_of GO:0005771 ! multivesicular body
created_by: pr
creation_date: 2013-07-08T20:34:51Z
@@ -425871,8 +440784,7 @@
name: multivesicular body, internal vesicle membrane
namespace: cellular_component
def: "The lipid bilayer surrounding a multivesicular body internal vesicle." [GOC:pde, PMID:21183070]
-is_a: GO:0030659 ! cytoplasmic vesicle membrane
-is_a: GO:0098588 ! bounding membrane of organelle
+is_a: GO:0160314 ! endosomal intralumenal vesicle membrane
relationship: part_of GO:0097487 ! multivesicular body, internal vesicle
created_by: pr
creation_date: 2013-07-08T20:36:33Z
@@ -425883,7 +440795,7 @@
namespace: cellular_component
def: "The volume enclosed by the membrane of the multivesicular body internal vesicle." [GOC:pde, PMID:21183070]
is_a: GO:0031983 ! vesicle lumen
-is_a: GO:0070013 ! intracellular organelle lumen
+is_a: GO:0160315 ! endosomal intralumenal vesicle lumen
relationship: part_of GO:0097487 ! multivesicular body, internal vesicle
created_by: pr
creation_date: 2013-07-08T20:38:36Z
@@ -427413,11 +442325,17 @@
id: GO:0097620
name: (R)-mandelate dehydrogenase activity
namespace: molecular_function
-def: "Catalysis of the reaction: (R)-2-hydroxy-2-phenylacetate + acceptor = phenylglyoxylate + reduced acceptor." [GOC:pr, PMID:1731758, RHEA:43112]
+def: "Catalysis of the reaction: (R)-mandelate + NAD+ = phenylglyoxylate + NADH + H+." [PMID:1731758, RHEA:43112]
comment: In the yeast Rhodotorula graminis, (R)-mandelate dehydrogenase is the first enzyme of the mandelate pathway, and catalyzes the NAD-dependent oxidation of (R)-mandelate to phenylglyoxylate.
synonym: "D-mandelate dehydrogenase activity" EXACT []
+xref: EC:1.1.1.379
+xref: MetaCyc:RXN-15840
xref: RHEA:43112
-is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors
+is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.379
+property_value: skos:exactMatch MetaCyc:RXN-15840
+property_value: skos:exactMatch RHEA:43112
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: pr
creation_date: 2014-07-30T09:53:23Z
@@ -427429,7 +442347,10 @@
comment: Acts on primary amines, and also on some secondary and tertiary amines. It differs from EC:1.4.3.21, primary amine oxidase as it can oxidize secondary and tertiary amines but not methylamine.
synonym: "amine:oxygen oxidoreductase (deaminating) activity" EXACT []
xref: EC:1.4.3.4
+xref: RHEA:26414
is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.4.3.4
+property_value: skos:narrowMatch RHEA:26414
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22282" xsd:anyURI
created_by: pr
creation_date: 2014-07-30T10:23:57Z
@@ -427662,12 +442583,18 @@
id: GO:0097641
name: alpha-ketoglutarate-dependent xanthine dioxygenase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 2-oxoglutarate (alpha-ketoglutarate) + O2 + xanthine = CO2 + succinate + urate." [GOC:vw, PMID:15948966, PMID:17429948, RHEA:43120]
+def: "Catalysis of the reaction: xanthine + 2-oxoglutarate + O2 = urate + succinate + CO2." [PMID:15948966, PMID:17429948, RHEA:43120]
synonym: "2-oxoglutarate-dependent xanthine dioxygenase activity" EXACT []
synonym: "alpha-ketoglutarate- and Fe(II)-dependent xanthine dioxygenase activity" RELATED []
synonym: "alpha-ketoglutarate- and Fe(II)-dependent xanthine hydroxylase activity" RELATED []
+xref: EC:1.14.11.48
+xref: MetaCyc:RXN-15841
xref: RHEA:43120
-is_a: GO:0051213 ! dioxygenase activity
+is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.48
+property_value: skos:exactMatch MetaCyc:RXN-15841
+property_value: skos:exactMatch RHEA:43120
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: pr
creation_date: 2014-09-03T14:55:42Z
@@ -427832,6 +442759,9 @@
xref: EC:3.1.3.97
xref: RHEA:43532
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.97
+property_value: skos:exactMatch RHEA:43532
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2014-09-25T11:21:39Z
@@ -428221,7 +443151,9 @@
synonym: "tRNA 5-carboxymethoxyuridine methyltransferase activity" RELATED []
xref: RHEA:54080
is_a: GO:0016300 ! tRNA (uridine) methyltransferase activity
+property_value: skos:exactMatch RHEA:54080
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26117" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2016-01-07T10:36:46Z
@@ -428802,6 +443734,8 @@
def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 5'-end." [GOC:pf, PMID:22456265, PMID:27484477, PMID:30917604]
xref: RHEA:57528
is_a: GO:0097747 ! RNA polymerase activity
+property_value: skos:exactMatch RHEA:57528
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2016-12-02T11:51:31Z
@@ -429392,27 +444326,27 @@
[Term]
id: GO:0098514
-name: detection of high humidity stimulus involved in sensory perception
+name: obsolete detection of high humidity stimulus involved in sensory perception
namespace: biological_process
-def: "The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of high humidity." [GOC:dos, PMID:18269908]
-is_a: GO:0098512 ! detection of humidity stimulus involved in sensory perception
-is_a: GO:0098516 ! detection of high humidity
-intersection_of: GO:0098516 ! detection of high humidity
-intersection_of: part_of GO:0098510 ! sensory perception of high humidity
-relationship: part_of GO:0098510 ! sensory perception of high humidity
+def: "OBSOLETE. The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of high humidity." [GOC:dos, PMID:18269908]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0098510
+consider: GO:0098516
created_by: dos
creation_date: 2013-09-25T14:20:54Z
[Term]
id: GO:0098515
-name: detection of low humidity stimulus involved in sensory perception
+name: obsolete detection of low humidity stimulus involved in sensory perception
namespace: biological_process
-def: "The series of events in which a low humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of low humidity." [GOC:dos, PMID:18269908]
-is_a: GO:0098512 ! detection of humidity stimulus involved in sensory perception
-is_a: GO:0098517 ! detection of low humidity
-intersection_of: GO:0098517 ! detection of low humidity
-intersection_of: part_of GO:0098511 ! sensory perception of low humidity
-relationship: part_of GO:0098511 ! sensory perception of low humidity
+def: "OBSOLETE. The series of events in which a low humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of low humidity." [GOC:dos, PMID:18269908]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0098511
+consider: GO:0098517
created_by: dos
creation_date: 2013-09-25T14:24:29Z
@@ -430267,6 +445201,8 @@
xref: Reactome:R-HSA-2408551 "SeMet is converted to AdoSeMet by MAT"
xref: RHEA:31211
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch RHEA:31211
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
created_by: dos
creation_date: 2014-04-15T15:15:03Z
@@ -430310,6 +445246,8 @@
xref: Reactome:R-HSA-2408543 "SeCysta is hydrolysed to Sec by PXLP-K212-CTH"
xref: RHEA:31151
is_a: GO:0016846 ! carbon-sulfur lyase activity
+property_value: skos:exactMatch RHEA:31151
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
created_by: dos
creation_date: 2014-04-16T11:20:00Z
@@ -430443,6 +445381,9 @@
xref: RHEA:25041
is_a: GO:0016785 ! selenotransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.9.1.2
+property_value: skos:exactMatch RHEA:25041
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
@@ -430456,6 +445397,7 @@
xref: RHEA:34927
is_a: GO:0015036 ! disulfide oxidoreductase activity
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
+property_value: skos:exactMatch RHEA:34927
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
[Term]
@@ -430503,8 +445445,11 @@
xref: EC:3.9.1.2
xref: RHEA:43380
is_a: GO:0004721 ! phosphoprotein phosphatase activity
-is_a: GO:0016825 ! hydrolase activity, acting on acid phosphorus-nitrogen bonds
+is_a: GO:0016825 ! hydrolase activity, acting on phosphorus-nitrogen bonds
+property_value: skos:exactMatch EC:3.9.1.2
+property_value: skos:exactMatch RHEA:43380
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21517" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: dos
creation_date: 2014-04-17T17:57:39Z
@@ -430650,15 +445595,16 @@
def: "A collagen trimer that forms networks." [PMID:21421911]
is_a: GO:0005581 ! collagen trimer
intersection_of: GO:0005581 ! collagen trimer
-intersection_of: part_of GO:0098645 ! collagen network
-relationship: part_of GO:0098645 ! collagen network
+intersection_of: part_of GO:0098645 ! complex of network-forming collagens
+relationship: part_of GO:0098645 ! complex of network-forming collagens
[Term]
id: GO:0098643
-name: fibrillar collagen
+name: fibrillar collagen complex
namespace: cellular_component
def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:20386646, PMID:21421911, PMID:29853175]
synonym: "banded collagen fibril" EXACT []
+synonym: "fibrillar collagen" EXACT []
is_a: GO:0098644 ! complex of collagen trimers
relationship: part_of GO:0140152 ! collagenous component of interstitial matrix
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29474" xsd:anyURI
@@ -430677,10 +445623,12 @@
[Term]
id: GO:0098645
-name: collagen network
+name: complex of network-forming collagens
namespace: cellular_component
def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911]
+synonym: "collagen network" EXACT []
is_a: GO:0098644 ! complex of collagen trimers
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30938" xsd:anyURI
[Term]
id: GO:0098646
@@ -430688,7 +445636,7 @@
namespace: cellular_component
def: "A hexagonal shaped collagen network formed by collagen type X trimer, mostly found in the cartilage hyaline matrix, which located in the interstitial area." [PMID:21421911, PMID:34948124]
synonym: "collagen hexagonal network" EXACT [PMID:21421911]
-is_a: GO:0098645 ! collagen network
+is_a: GO:0098645 ! complex of network-forming collagens
relationship: part_of GO:0140152 ! collagenous component of interstitial matrix
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29415" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30146" xsd:anyURI
@@ -430743,10 +445691,13 @@
[Term]
id: GO:0098652
-name: collagen type VII anchoring fibril
+name: obsolete collagen type VII anchoring fibril
namespace: cellular_component
-def: "An antiparallel dimer of two collagen VII trimers, one end of which is embedded in the lamina densa while the other end attaches to banded collagen fibrils in the dermis." [PMID:19693541]
-is_a: GO:0098648 ! collagen anchoring fibril
+def: "OBSOLETE. An antiparallel dimer of two collagen VII trimers, one end of which is embedded in the lamina densa while the other end attaches to banded collagen fibrils in the dermis." [PMID:19693541]
+comment: This term was obsoleted because it was redundant with collagen type VII trimer ; GO:0005590.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30939" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0005590
[Term]
id: GO:0098653
@@ -431036,7 +445987,7 @@
[Term]
id: GO:0098680
-name: template-free RNA nucleotidyltransferase
+name: template-free RNA nucleotidyltransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the addition of a terminal nucleotide to an RNA molecule in the absence of a nucleic acid template." [GOC:BHF, GOC:BHF_telomere, GOC:dos, GOC:nc, PMID:15994230]
is_a: GO:0016779 ! nucleotidyltransferase activity
@@ -431233,14 +446184,14 @@
[Term]
id: GO:0098697
-name: ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels
+name: obsolete obsolete ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels
namespace: molecular_function
-def: "Any ryanodine-sensitive calcium-release channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration." [GOC:dos]
-subset: goslim_synapse
-is_a: GO:0005219 ! ryanodine-sensitive calcium-release channel activity
-is_a: GO:1905058 ! calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration
-intersection_of: GO:0005219 ! ryanodine-sensitive calcium-release channel activity
-intersection_of: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration
+def: "OBSOLETE. OBSOLETE. Any ryanodine-sensitive calcium-release channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration." [GOC:dos]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31205" xsd:anyURI
+is_obsolete: true
+consider: GO:0005219
+consider: GO:0099566
created_by: dos
creation_date: 2017-04-04T17:11:38Z
@@ -431622,11 +446573,12 @@
[Term]
id: GO:0098731
-name: skeletal muscle satellite stem cell maintenance involved in skeletal muscle regeneration
+name: obsolete skeletal muscle satellite stem cell maintenance involved in skeletal muscle regeneration
namespace: biological_process
-def: "Any process by which the number of skeletal muscle satellite stem cells in a skeletal muscle is maintained during skeletal muscle regeneration. There are at least two mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells." [PMID:23303905]
-is_a: GO:0014834 ! skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
-is_a: GO:0035019 ! somatic stem cell population maintenance
+def: "OBSOLETE. Any process by which the number of skeletal muscle satellite stem cells in a skeletal muscle is maintained during skeletal muscle regeneration. There are at least two mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells." [PMID:23303905]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0098732
@@ -431709,7 +446661,6 @@
name: 1-phosphatidylinositol 4-kinase activator activity
namespace: molecular_function
def: "Binds to and increases the activity of 1-phosphatidylinositol 4-kinase." [PMID:21288895]
-xref: Reactome:R-HSA-1676152 "PI4KB binds to ARF1/3:GTP at the Golgi membrane"
is_a: GO:0019209 ! kinase activator activity
relationship: positively_regulates GO:0004430 ! 1-phosphatidylinositol 4-kinase activity
@@ -432419,6 +447370,7 @@
def: "Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity." [GOC:BHF, GOC:dos]
is_a: GO:0004675 ! transmembrane receptor protein serine/threonine kinase activity
relationship: part_of GO:0030509 ! BMP signaling pathway
+property_value: skos:broadMatch EC:2.7.11.30
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
[Term]
@@ -432694,6 +447646,9 @@
xref: EC:4.7.1.1
xref: RHEA:34707
is_a: GO:0018835 ! carbon phosphorus lyase activity
+property_value: skos:exactMatch EC:4.7.1.1
+property_value: skos:exactMatch RHEA:34707
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0098849
@@ -432918,16 +447873,15 @@
[Term]
id: GO:0098872
-name: G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
+name: obsolete G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
namespace: molecular_function
-def: "A G protein-coupled neurotransmitter receptor activity occurring in the postsynaptic membrane, that is involved in regulating the cytosolic concentration of calcium ions in the postsynapse." [GOC:dos]
-subset: goslim_synapse
+def: "OBSOLETE. A G protein-coupled neurotransmitter receptor activity occurring in the postsynaptic membrane, that is involved in regulating the cytosolic concentration of calcium ions in the postsynapse." [GOC:dos]
+comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
synonym: "G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT []
synonym: "G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels" EXACT syngo_official_label []
-is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity
-is_a: GO:0099583 ! neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
-intersection_of: GO:0099528 ! G protein-coupled neurotransmitter receptor activity
-intersection_of: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31205" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0099528
[Term]
id: GO:0098873
@@ -434645,6 +449599,7 @@
synonym: "ceramide-translocating ATPase activity" BROAD []
is_a: GO:0046623 ! sphingolipid floppase activity
relationship: part_of GO:0099040 ! ceramide translocation
+property_value: skos:broadMatch RHEA:66132
[Term]
id: GO:0099039
@@ -435215,14 +450170,14 @@
[Term]
id: GO:0099102
-name: G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential
+name: obsolete G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential
namespace: molecular_function
-def: "Any G-protein gated potassium channel activity that is involved regulation of postsynaptic membrane potential." [GOC:dos, PMID:9429760]
-subset: goslim_synapse
-is_a: GO:0099101 ! G-protein gated potassium channel activity
-intersection_of: GO:0099101 ! G-protein gated potassium channel activity
-intersection_of: part_of GO:0060078 ! regulation of postsynaptic membrane potential
-relationship: part_of GO:0060078 ! regulation of postsynaptic membrane potential
+def: "OBSOLETE. Any G-protein gated potassium channel activity that is involved regulation of postsynaptic membrane potential." [GOC:dos, PMID:9429760]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060078
+consider: GO:0099101
[Term]
id: GO:0099103
@@ -435239,7 +450194,6 @@
name: potassium channel activator activity
namespace: molecular_function
def: "Binds to and increases the activity of a potassium channel, resulting in its opening." [GOC:dos]
-xref: Reactome:R-HSA-400063 "Low conductance potassium channels in pancreatic beta cells open in response to epinephrine"
is_a: GO:0015459 ! potassium channel regulator activity
is_a: GO:0099103 ! channel activator activity
relationship: positively_regulates GO:0005267 ! potassium channel activity
@@ -435454,7 +450408,7 @@
id: GO:0099126
name: transforming growth factor beta complex
namespace: cellular_component
-def: "A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerization and dissociation of the LAP." [GOC:bhm, PMID:22943793]
+def: "A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerization and dissociation of the LAP." [PMID:22943793, PMID:25960420, PMID:27252363, PMID:29217273]
synonym: "TGF-beta complex" EXACT []
synonym: "TGF-beta dimer" EXACT []
synonym: "TGFB complex" EXACT []
@@ -435462,7 +450416,9 @@
synonym: "TGFbeta complex" EXACT []
synonym: "TGFbeta dimer" EXACT []
is_a: GO:0032991 ! protein-containing complex
-relationship: part_of GO:0031012 ! extracellular matrix
+relationship: part_of GO:0005576 ! extracellular region
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31130" xsd:anyURI
+created_by: bhm
[Term]
id: GO:0099127
@@ -436483,29 +451439,27 @@
[Term]
id: GO:0099520
-name: monoatomic ion antiporter activity involved in regulation of presynaptic membrane potential
+name: obsolete monoatomic ion antiporter activity involved in regulation of presynaptic membrane potential
namespace: molecular_function
-def: "Any ion antiporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential." [GOC:dos]
-subset: goslim_synapse
+def: "OBSOLETE. Any ion antiporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential." [GOC:dos]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "ion antiporter activity involved in regulation of pre-synaptic membrane potential" EXACT []
synonym: "ion antiporter activity involved in regulation of presynaptic membrane potential" EXACT []
-is_a: GO:0015297 ! antiporter activity
-relationship: occurs_in GO:0042734 ! presynaptic membrane
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0099521
-name: ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential
+name: obsolete ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential
namespace: molecular_function
-def: "Any ATPase coupled ion transmembrane transporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential." [GOC:dos, PMID:17220883]
-subset: goslim_synapse
+def: "OBSOLETE. Any ATPase coupled ion transmembrane transporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential." [GOC:dos, PMID:17220883]
+comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
synonym: "ATPase coupled ion transmembrane transporter activity involved in regulation of pre-synaptic membrane potential" EXACT []
synonym: "ATPase-coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential" EXACT []
-is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity
-intersection_of: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity
-intersection_of: part_of GO:0099505 ! regulation of presynaptic membrane potential
-relationship: occurs_in GO:0042734 ! presynaptic membrane
-relationship: part_of GO:0099505 ! regulation of presynaptic membrane potential
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31205" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0042625
[Term]
id: GO:0099522
@@ -437102,55 +452056,50 @@
[Term]
id: GO:0099579
-name: G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
+name: obsolete G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
namespace: molecular_function
-def: "A G protein-coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane, involved in regulation of postsynaptic membrane potential." [GOC:dos]
-subset: goslim_synapse
+def: "OBSOLETE. A G protein-coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane, involved in regulation of postsynaptic membrane potential." [GOC:dos]
+comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
synonym: "G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential" EXACT []
-is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity
-is_a: GO:0099529 ! neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
-is_a: GO:0099530 ! G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential
-intersection_of: GO:0099528 ! G protein-coupled neurotransmitter receptor activity
-intersection_of: part_of GO:0060078 ! regulation of postsynaptic membrane potential
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31205" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0099528
[Term]
id: GO:0099580
-name: monoatomic ion antiporter activity involved in regulation of postsynaptic membrane potential
+name: obsolete monoatomic ion antiporter activity involved in regulation of postsynaptic membrane potential
namespace: molecular_function
-def: "Any ion antiporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential." [GOC:dos]
-subset: goslim_synapse
+def: "OBSOLETE. Any ion antiporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential." [GOC:dos]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "ion antiporter activity involved in regulation of post-synaptic membrane potential" EXACT []
synonym: "ion antiporter activity involved in regulation of postsynaptic membrane potential" EXACT []
-is_a: GO:0015297 ! antiporter activity
-relationship: occurs_in GO:0045211 ! postsynaptic membrane
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
[Term]
id: GO:0099581
-name: ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential
+name: obsolete ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential
namespace: molecular_function
-def: "Any ATPase coupled ion transmembrane transporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential." [GOC:dos]
-subset: goslim_synapse
+def: "OBSOLETE. Any ATPase coupled ion transmembrane transporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential." [GOC:dos]
+comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
synonym: "ATPase coupled ion transmembrane transporter activity involved in regulation of post-synaptic membrane potential" EXACT []
synonym: "ATPase-coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential" EXACT []
-is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity
-intersection_of: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity
-intersection_of: part_of GO:0060078 ! regulation of postsynaptic membrane potential
-relationship: occurs_in GO:0045211 ! postsynaptic membrane
-relationship: part_of GO:0060078 ! regulation of postsynaptic membrane potential
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31205" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0042625
[Term]
id: GO:0099582
-name: neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration
+name: obsolete neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration
namespace: molecular_function
-def: "Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the presynaptic cytosol." [GOC:dos]
-subset: goslim_synapse
+def: "OBSOLETE. Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the presynaptic cytosol." [GOC:dos]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels" EXACT syngo_official_label []
-is_a: GO:0030594 ! neurotransmitter receptor activity
-intersection_of: GO:0030594 ! neurotransmitter receptor activity
-intersection_of: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration
-relationship: occurs_in GO:0042734 ! presynaptic membrane
-relationship: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0030594
+consider: GO:0099509
[Term]
id: GO:0099583
@@ -437264,10 +452213,6 @@
name: ligand-gated calcium channel activity
namespace: molecular_function
def: "Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts." [GOC:dos]
-xref: Reactome:R-HSA-1168376 "STIM1 oligomerizes"
-xref: Reactome:R-HSA-169680 "IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel"
-xref: Reactome:R-HSA-169683 "IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol"
-xref: Reactome:R-HSA-4420052 "Decreasing cGMP concentration promotes intracellular Ca2+ release in response to WNT"
is_a: GO:0005262 ! calcium channel activity
is_a: GO:0099094 ! ligand-gated monoatomic cation channel activity
relationship: part_of GO:0019722 ! calcium-mediated signaling
@@ -437365,6 +452310,9 @@
xref: MetaCyc:RXN-18432
xref: RHEA:51608
is_a: GO:0051990 ! (R)-2-hydroxyglutarate dehydrogenase activity
+property_value: skos:exactMatch EC:1.1.99.40
+property_value: skos:exactMatch MetaCyc:RXN-18432
+property_value: skos:exactMatch RHEA:51608
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30707" xsd:anyURI
[Term]
@@ -437396,6 +452344,9 @@
xref: MetaCyc:RXN0-1861
xref: RHEA:24702
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.305
+property_value: skos:exactMatch MetaCyc:RXN0-1861
+property_value: skos:exactMatch RHEA:24702
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29382" xsd:anyURI
[Term]
@@ -437409,12 +452360,15 @@
xref: EC:2.1.2.13
xref: RHEA:24706
is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity
+property_value: skos:exactMatch EC:2.1.2.13
+property_value: skos:exactMatch RHEA:24706
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0099620
-name: UDP-4-amino-4-deoxy-L-arabinose aminotransferase
+name: UDP-4-amino-4-deoxy-L-arabinose aminotransferase activity
namespace: molecular_function
-def: "Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinopyranose + 2-oxoglutarate = UDP-beta-L-threo-pentapyranos-4-ulose + L-glutamate." [GOC:al, GOC:dos, PMID:12429098, PMID:12704196]
+def: "Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinose + 2-oxoglutarate = UDP-beta-L-threo-pentopyranos-4-ulose + L-glutamate." [PMID:12429098, PMID:12704196, RHEA:24710]
synonym: "UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase" EXACT []
synonym: "UDP-4-amino-4-deoxy-beta-L-arabinose:2-oxoglutarate aminotransferase" EXACT []
synonym: "UDP-4-amino-4-deoxy-L-arabinose---oxoglutarate aminotransferase" EXACT []
@@ -437423,6 +452377,9 @@
xref: EC:2.6.1.87
xref: RHEA:24710
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.87
+property_value: skos:exactMatch RHEA:24710
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0099621
@@ -437437,6 +452394,9 @@
xref: MetaCyc:RXN0-3521
xref: RHEA:27722
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.53
+property_value: skos:exactMatch RHEA:27722
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0099622
@@ -438482,7 +453442,6 @@
comment: There are two main classes of deubiquitinating enzymes: cysteine proteases (i.e., thiol dependent) and metalloproteases.
synonym: "ubiquitinyl hydrolase activity" EXACT []
xref: Reactome:R-HSA-9674127 "USP30 deubiquitinates ATM dimer:Ub-p-PEX5"
-xref: Reactome:R-HSA-9929353 "Deubiquitination of CD274"
is_a: GO:0019783 ! ubiquitin-like protein peptidase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17398" xsd:anyURI
created_by: mec
@@ -438497,9 +453456,15 @@
comment: This eukaryotic enzyme dephosphorylates phosphorylated histidine residues within proteins and peptides. The enzyme acts on phosphate groups attached to both the pros- (RHEA:47964) and tele- (RHEA:47960) nitrogen atoms, but the pros- position is somewhat preferred (by a factor of two at the most) (EC:3.9.1.3).
synonym: "phosphohistidine phosphatase activity" BROAD []
xref: EC:3.9.1.3
+xref: RHEA:47960
+xref: RHEA:47964
is_a: GO:0004721 ! phosphoprotein phosphatase activity
-is_a: GO:0016825 ! hydrolase activity, acting on acid phosphorus-nitrogen bonds
+is_a: GO:0016825 ! hydrolase activity, acting on phosphorus-nitrogen bonds
+property_value: skos:exactMatch EC:3.9.1.3
+property_value: skos:narrowMatch RHEA:47960
+property_value: skos:narrowMatch RHEA:47964
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21517" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0101007
@@ -438597,8 +453562,12 @@
namespace: molecular_function
def: "Catalysis of the reaction: estrogen + reduced [NADPH--hemoprotein reductase] + O2 = 16-alpha-hydroxyestrogen + oxidized [NADPH--hemoprotein reductase] + H2O." [GOC:BHF]
synonym: "oestrogen 16-alpha-hydroxylase activity" EXACT []
+xref: RHEA:47204
+xref: RHEA:47332
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:narrowMatch RHEA:47204
+property_value: skos:narrowMatch RHEA:47332
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29025" xsd:anyURI
[Term]
@@ -438607,8 +453576,12 @@
namespace: molecular_function
def: "Catalysis of the reaction: estrogen + reduced [NADPH--hemoprotein reductase] + O2 = 2-hydroxyestrogen + H+ + H2O + oxidized [NADPH--hemoprotein reductase]." [GOC:BHF, GOC:rl, PMID:14559847]
synonym: "oestrogen 2-hydroxylase activity" EXACT []
+xref: RHEA:47208
+xref: RHEA:47212
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:narrowMatch RHEA:47208
+property_value: skos:narrowMatch RHEA:47212
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29035" xsd:anyURI
[Term]
@@ -438705,6 +453678,9 @@
xref: MetaCyc:1.14.13.117-RXN
xref: RHEA:28602
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.39
+property_value: skos:exactMatch RHEA:28602
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102002
@@ -438715,6 +453691,9 @@
xref: MetaCyc:1.14.13.118-RXN
xref: RHEA:28606
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.38
+property_value: skos:exactMatch RHEA:28606
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102003
@@ -438725,8 +453704,18 @@
synonym: "Delta(8)-desaturase" EXACT [EC:1.14.19.4]
synonym: "Delta8-sphingolipid desaturase activity" EXACT []
xref: EC:1.14.19.4
+xref: MetaCyc:RXN-16099
+xref: MetaCyc:RXN-16101
+xref: RHEA:46792
+xref: RHEA:46796
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.4
+property_value: skos:narrowMatch MetaCyc:RXN-16099
+property_value: skos:narrowMatch MetaCyc:RXN-16101
+property_value: skos:narrowMatch RHEA:46792
+property_value: skos:narrowMatch RHEA:46796
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25968" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102004
@@ -438759,6 +453748,9 @@
xref: Reactome:R-HSA-9756177 "PON1,3 hydrolyse ATVL to ATV"
xref: RHEA:22576
is_a: GO:0046573 ! lactonohydrolase activity
+property_value: skos:exactMatch EC:3.1.1.81
+property_value: skos:exactMatch RHEA:22576
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102009
@@ -438769,7 +453761,10 @@
xref: MetaCyc:3.4.13.9-RXN
xref: RHEA:76407
is_a: GO:0016805 ! dipeptidase activity
+property_value: skos:exactMatch EC:3.4.13.9
+property_value: skos:exactMatch RHEA:76407
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28173" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102013
@@ -438780,6 +453775,8 @@
xref: MetaCyc:ABC-13-RXN
xref: RHEA:29035
is_a: GO:0015426 ! ATPase-coupled polar amino acid-transporter activity
+property_value: skos:exactMatch RHEA:29035
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
@@ -438789,8 +453786,10 @@
def: "Catalysis of the reaction: ATP(4-) + beta-D-galactoside + H2O = ADP(3-) + hydrogenphosphate + beta-D-galactoside + H+." [RHEA:30011]
xref: RHEA:30011
is_a: GO:0015407 ! ABC-type monosaccharide transporter activity
+property_value: skos:exactMatch RHEA:30011
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102025
@@ -438805,6 +453804,8 @@
xref: RHEA:29871
is_a: GO:0015117 ! thiosulfate transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:broadMatch EC:7.3.2.3
+property_value: skos:exactMatch RHEA:29871
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14642" xsd:anyURI
[Term]
@@ -438838,7 +453839,10 @@
xref: RHEA:51468
is_a: GO:0047809 ! D-lactate dehydrogenase activity
is_a: GO:1990464 ! (2R)-hydroxyacid dehydrogenase (quinone) activity
+property_value: skos:exactMatch EC:1.1.5.12
+property_value: skos:exactMatch RHEA:51468
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30138" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102030
@@ -438858,6 +453862,9 @@
xref: MetaCyc:FUC4NACTRANS-RXN
xref: RHEA:28759
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.325
+property_value: skos:exactMatch RHEA:28759
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102033
@@ -438870,8 +453877,11 @@
xref: MetaCyc:RXN-16394
xref: RHEA:56748
is_a: GO:0120250 ! fatty acid omega-hydroxylase activity
+property_value: skos:exactMatch EC:1.14.14.80
+property_value: skos:exactMatch RHEA:56748
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14194" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19899" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102035
@@ -438892,6 +453902,9 @@
xref: MetaCyc:METHCOCLTH-RXN
xref: RHEA:45200
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.258
+property_value: skos:exactMatch RHEA:45200
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102037
@@ -438920,6 +453933,9 @@
xref: Reactome:R-HSA-1222526 "AhpC reduces peroxidated lipids"
xref: RHEA:62628
is_a: GO:0051920 ! peroxiredoxin activity
+property_value: skos:exactMatch EC:1.11.1.26
+property_value: skos:exactMatch RHEA:62628
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102040
@@ -438934,13 +453950,16 @@
[Term]
id: GO:0102041
-name: 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase
+name: 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphoric acid." [GOC:pz, RHEA:35951]
+def: "Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphoric acid." [RHEA:35951]
xref: EC:2.5.1.105
xref: MetaCyc:RXN-10009
xref: RHEA:35951
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.105
+property_value: skos:exactMatch RHEA:35951
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102042
@@ -438951,6 +453970,9 @@
xref: MetaCyc:RXN-10032
xref: RHEA:25956
is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.4.1.24
+property_value: skos:exactMatch RHEA:25956
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102043
@@ -438961,6 +453983,9 @@
xref: MetaCyc:RXN-10068
xref: RHEA:33963
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
+property_value: skos:exactMatch EC:2.7.4.26
+property_value: skos:exactMatch RHEA:33963
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102044
@@ -439055,7 +454080,10 @@
xref: EC:3.7.1.23
xref: MetaCyc:RXN-10447
xref: RHEA:47956
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.23
+property_value: skos:exactMatch RHEA:47956
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102055
@@ -439113,6 +454141,9 @@
xref: MetaCyc:RXN-10481
xref: RHEA:27810
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.92
+property_value: skos:exactMatch MetaCyc:RXN-10481
+property_value: skos:exactMatch RHEA:27810
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -439126,6 +454157,9 @@
xref: MetaCyc:RXN-10482
xref: RHEA:30471
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.54
+property_value: skos:exactMatch RHEA:30471
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102061
@@ -439139,6 +454173,9 @@
xref: MetaCyc:RXN-10483
xref: RHEA:30467
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.53
+property_value: skos:exactMatch RHEA:30467
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102062
@@ -439149,6 +454186,9 @@
xref: MetaCyc:RXN-10567
xref: RHEA:30463
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.50
+property_value: skos:exactMatch RHEA:30463
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102063
@@ -439168,6 +454208,9 @@
xref: MetaCyc:RXN-10599
xref: RHEA:32031
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.94
+property_value: skos:exactMatch RHEA:32031
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102065
@@ -439196,6 +454239,9 @@
xref: MetaCyc:RXN-10625
xref: RHEA:26229
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.83
+property_value: skos:exactMatch RHEA:26229
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102068
@@ -439206,6 +454252,9 @@
xref: MetaCyc:RXN-10628
xref: RHEA:32491
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.113
+property_value: skos:exactMatch RHEA:32491
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102069
@@ -439216,6 +454265,9 @@
xref: MetaCyc:RXN-10629
xref: RHEA:32327
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.326
+property_value: skos:exactMatch RHEA:32327
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102070
@@ -439285,6 +454337,9 @@
xref: MetaCyc:RXN-10741
xref: RHEA:26389
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.71
+property_value: skos:exactMatch RHEA:26389
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102080
@@ -439295,6 +454350,9 @@
xref: MetaCyc:RXN-10821
xref: RHEA:27850
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.192
+property_value: skos:exactMatch RHEA:27850
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102081
@@ -439314,6 +454372,9 @@
xref: MetaCyc:RXN-10847
xref: RHEA:27353
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.164
+property_value: skos:exactMatch RHEA:27353
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102083
@@ -439403,6 +454464,7 @@
xref: RHEA:41147
is_a: GO:0034595 ! phosphatidylinositol phosphate 5-phosphatase activity
is_a: GO:0052744 ! phosphatidylinositol monophosphate phosphatase activity
+property_value: skos:exactMatch RHEA:41147
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24252" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30249" xsd:anyURI
@@ -439434,6 +454496,9 @@
xref: MetaCyc:RXN-11070
xref: RHEA:34487
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.289
+property_value: skos:exactMatch RHEA:34487
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102097
@@ -439443,7 +454508,12 @@
synonym: "(22S)-22-hydroxy-5alpha-campestan-3-one C-23 hydroxylase activity" EXACT []
xref: EC:1.14.14.147
xref: MetaCyc:RXN-11101
+xref: RHEA:27321
+xref: RHEA:27325
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.147
+property_value: skos:narrowMatch RHEA:27321
+property_value: skos:narrowMatch RHEA:27325
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -439455,6 +454525,9 @@
xref: MetaCyc:RXN-11151
xref: RHEA:26345
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.365
+property_value: skos:exactMatch RHEA:26345
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102099
@@ -439465,6 +454538,9 @@
xref: MetaCyc:RXN-11186
xref: RHEA:27329
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.113
+property_value: skos:exactMatch RHEA:27329
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102100
@@ -439475,6 +454551,9 @@
xref: MetaCyc:RXN-11187
xref: RHEA:27349
is_a: GO:0050497 ! alkylthioltransferase activity
+property_value: skos:exactMatch EC:2.8.4.2
+property_value: skos:exactMatch RHEA:27349
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102102
@@ -439490,7 +454569,16 @@
namespace: molecular_function
def: "Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + 4-coumaryl-CoA + H2O = bisdemethoxycurcumin + 2 coenzyme A + carbon dioxide." [EC:2.3.1.219]
xref: EC:2.3.1.219
+xref: MetaCyc:RXN-11223
+xref: MetaCyc:RXN-11225
+xref: RHEA:35119
+xref: RHEA:35139
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.219
+property_value: skos:narrowMatch MetaCyc:RXN-11223
+property_value: skos:narrowMatch MetaCyc:RXN-11225
+property_value: skos:narrowMatch RHEA:35119
+property_value: skos:narrowMatch RHEA:35139
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -439522,6 +454610,9 @@
xref: MetaCyc:RXN-11226
xref: RHEA:34823
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.217
+property_value: skos:exactMatch RHEA:34823
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102109
@@ -439578,6 +454669,9 @@
xref: MetaCyc:RXN-11358
xref: RHEA:36119
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.275
+property_value: skos:exactMatch RHEA:36119
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102118
@@ -439588,6 +454682,9 @@
xref: MetaCyc:RXN-11359
xref: RHEA:36107
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.276
+property_value: skos:exactMatch RHEA:36107
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102119
@@ -439664,6 +454761,9 @@
xref: MetaCyc:RXN-11455
xref: RHEA:32067
is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
+property_value: skos:exactMatch EC:3.5.4.32
+property_value: skos:exactMatch RHEA:32067
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102128
@@ -439684,6 +454784,9 @@
xref: MetaCyc:RXN-11475
xref: RHEA:17105
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.197
+property_value: skos:exactMatch RHEA:17105
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102131
@@ -439780,6 +454883,7 @@
xref: RHEA:70587
is_a: GO:0019213 ! deacetylase activity
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch RHEA:70587
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
[Term]
@@ -439810,7 +454914,16 @@
synonym: "carboxynorspermidine dehydrogenase I activity" NARROW []
synonym: "carboxynorspermidine dehydrogenase II activity" NARROW []
xref: EC:1.5.1.43
+xref: MetaCyc:RXN-11565
+xref: MetaCyc:RXN-11566
+xref: RHEA:34111
+xref: RHEA:34115
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.43
+property_value: skos:narrowMatch MetaCyc:RXN-11565
+property_value: skos:narrowMatch MetaCyc:RXN-11566
+property_value: skos:narrowMatch RHEA:34111
+property_value: skos:narrowMatch RHEA:34115
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28857" xsd:anyURI
[Term]
@@ -439832,6 +454945,9 @@
xref: MetaCyc:RXN-11575
xref: RHEA:27534
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.49
+property_value: skos:exactMatch RHEA:27534
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102146
@@ -439841,6 +454957,8 @@
xref: MetaCyc:RXN-11582
xref: RHEA:27493
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch RHEA:27493
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102147
@@ -439871,6 +454989,9 @@
xref: MetaCyc:RXN-11623
xref: RHEA:30231
is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.8.3.6
+property_value: skos:exactMatch RHEA:30231
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102150
@@ -439920,6 +455041,9 @@
xref: MetaCyc:RXN-11689
xref: RHEA:28194
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.310
+property_value: skos:exactMatch RHEA:28194
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102156
@@ -439948,8 +455072,11 @@
xref: MetaCyc:RXN-11750
xref: RHEA:45812
is_a: GO:0080023 ! (2E)-enoyl-CoA hydratase activity
+property_value: skos:exactMatch EC:4.2.1.134
+property_value: skos:exactMatch RHEA:45812
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24738" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25805" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102159
@@ -439959,6 +455086,8 @@
xref: MetaCyc:RXN-11755
xref: RHEA:28314
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:broadMatch EC:2.4.1.253
+property_value: skos:exactMatch RHEA:28314
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -439971,6 +455100,9 @@
xref: MetaCyc:RXN-11756
xref: RHEA:28258
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.254
+property_value: skos:exactMatch RHEA:28258
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102161
@@ -439981,6 +455113,9 @@
xref: MetaCyc:RXN-11772
xref: RHEA:32703
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.133
+property_value: skos:exactMatch RHEA:32703
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102162
@@ -439991,6 +455126,9 @@
xref: MetaCyc:RXN-11783
xref: RHEA:26385
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.75
+property_value: skos:exactMatch RHEA:26385
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102163
@@ -440010,6 +455148,9 @@
xref: MetaCyc:RXN-11849
xref: RHEA:37871
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.182
+property_value: skos:exactMatch RHEA:37871
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102165
@@ -440020,6 +455161,9 @@
xref: MetaCyc:RXN-11852
xref: RHEA:28254
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.195
+property_value: skos:exactMatch RHEA:28254
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102166
@@ -440050,6 +455194,9 @@
xref: MetaCyc:RXN-11897
xref: RHEA:49112
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.327
+property_value: skos:exactMatch MetaCyc:RXN-11897
+property_value: skos:exactMatch RHEA:49112
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -440059,7 +455206,16 @@
def: "Catalysis of the reaction: 5-methyl-phenazine-1-carboxylate + 2 H+ + NADH + O2 = CO2 + H2O + NAD+ + pyocyanin. Also converts phenazine-1-carboxylate into 1-hydroxyphenazine." [EC:1.14.13.218, PMID:11591691]
synonym: "pyocyanin hydroxylase activity" RELATED []
xref: EC:1.14.13.218
+xref: MetaCyc:RXN-11898
+xref: MetaCyc:RXN-17175
+xref: RHEA:48976
+xref: RHEA:53868
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.218
+property_value: skos:narrowMatch MetaCyc:RXN-11898
+property_value: skos:narrowMatch MetaCyc:RXN-17175
+property_value: skos:narrowMatch RHEA:48976
+property_value: skos:narrowMatch RHEA:53868
[Term]
id: GO:0102170
@@ -440070,6 +455226,9 @@
xref: MetaCyc:RXN-11908
xref: RHEA:28226
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.149
+property_value: skos:exactMatch RHEA:28226
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102171
@@ -440080,6 +455239,9 @@
xref: MetaCyc:RXN-11911
xref: RHEA:55424
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.59
+property_value: skos:exactMatch MetaCyc:RXN-11911
+property_value: skos:exactMatch RHEA:55424
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -440090,6 +455252,8 @@
xref: MetaCyc:RXN-11925
xref: RHEA:58860
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:58860
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102173
@@ -440118,6 +455282,8 @@
xref: MetaCyc:RXN-11928
xref: RHEA:34775
is_a: GO:0000252 ! 3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity
+property_value: skos:exactMatch EC:1.1.1.418
+property_value: skos:exactMatch RHEA:34775
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29311" xsd:anyURI
[Term]
@@ -440139,6 +455305,9 @@
xref: MetaCyc:RXN-11930
xref: RHEA:58872
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.18.11
+property_value: skos:exactMatch RHEA:58872
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102178
@@ -440166,6 +455335,8 @@
xref: MetaCyc:RXN-11936
xref: RHEA:59036
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:59036
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102181
@@ -440281,6 +455452,9 @@
xref: RHEA:48432
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.7.1.172
+property_value: skos:exactMatch RHEA:48432
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102194
@@ -440294,6 +455468,9 @@
xref: RHEA:59832
is_a: GO:0016301 ! kinase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.7.1.171
+property_value: skos:exactMatch RHEA:59832
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102195
@@ -440304,6 +455481,9 @@
xref: MetaCyc:RXN-12042
xref: RHEA:25273
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.37
+property_value: skos:exactMatch RHEA:25273
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102196
@@ -440313,7 +455493,9 @@
xref: MetaCyc:RXN-12085
xref: RHEA:68616
is_a: GO:0070524 ! 11-beta-hydroxysteroid dehydrogenase (NADP+) activity
+property_value: skos:exactMatch RHEA:68616
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102197
@@ -440333,6 +455515,8 @@
xref: MetaCyc:RXN-12107
xref: RHEA:21172
is_a: GO:0050572 ! L-idonate 5-dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.1.1.366
+property_value: skos:exactMatch RHEA:21172
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27573" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
@@ -440345,7 +455529,12 @@
synonym: "nitric oxide reductase activity (NAD(P)H-dependent) activity" EXACT []
xref: EC:1.7.1.14
xref: MetaCyc:RXN-12112
+xref: RHEA:29607
+xref: RHEA:29611
is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.7.1.14
+property_value: skos:narrowMatch RHEA:29607
+property_value: skos:narrowMatch RHEA:29611
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
[Term]
@@ -440362,9 +455551,15 @@
id: GO:0102201
name: (+)-2-epi-prezizaene synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 2-cis,6-trans-farnesyl diphosphate = (+)-2-epi-prezizaene + diphosphoric acid." [GOC:pz, PMID:20175559, PMID:20201526]
+def: "Catalysis of the reaction: (2Z,6E)-farnesyl diphosphate = (+)-2-epi-prezizaene + diphosphate." [PMID:20175559, PMID:20201526, RHEA:31415]
+xref: EC:4.2.3.226
xref: MetaCyc:RXN-12117
+xref: RHEA:31415
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.226
+property_value: skos:exactMatch MetaCyc:RXN-12117
+property_value: skos:exactMatch RHEA:31415
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0102202
@@ -440420,7 +455615,10 @@
xref: MetaCyc:RXN-12160
xref: RHEA:31411
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.222
+property_value: skos:exactMatch RHEA:31411
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28942" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102209
@@ -440431,6 +455629,9 @@
xref: MetaCyc:RXN-12167
xref: RHEA:30283
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.88
+property_value: skos:exactMatch RHEA:30283
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102210
@@ -440440,6 +455641,8 @@
xref: EC:4.2.2.23
xref: MetaCyc:RXN-12173
is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides
+property_value: skos:exactMatch EC:4.2.2.23
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102211
@@ -440450,6 +455653,9 @@
xref: MetaCyc:RXN-12174
xref: RHEA:30927
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.172
+property_value: skos:exactMatch RHEA:30927
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102212
@@ -440460,6 +455666,9 @@
xref: MetaCyc:RXN-12177
xref: RHEA:31647
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.180
+property_value: skos:exactMatch RHEA:31647
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102213
@@ -440490,6 +455699,9 @@
xref: MetaCyc:RXN-12189
xref: RHEA:28014
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.n4
+property_value: skos:exactMatch MetaCyc:RXN-12189
+property_value: skos:exactMatch RHEA:28014
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -440541,6 +455753,9 @@
xref: MetaCyc:RXN-12215
xref: RHEA:30279
is_a: GO:0016696 ! oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.12.1.4
+property_value: skos:exactMatch RHEA:30279
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102222
@@ -440553,7 +455768,7 @@
[Term]
id: GO:0102223
-name: 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)
+name: 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) activity
namespace: molecular_function
alt_id: GO:0102225
alt_id: GO:0102961
@@ -440565,8 +455780,15 @@
synonym: "4,4'-diapophytofluene desaturase activity" NARROW []
xref: EC:1.3.8.2
xref: MetaCyc:RXN-12224
+xref: MetaCyc:RXN-15614
xref: RHEA:31391
+xref: RHEA:42800
is_a: GO:0052890 ! oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
+property_value: skos:exactMatch EC:1.3.8.2
+property_value: skos:exactMatch MetaCyc:RXN-12224
+property_value: skos:exactMatch RHEA:31391
+property_value: skos:narrowMatch MetaCyc:RXN-15614
+property_value: skos:narrowMatch RHEA:42800
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23557" xsd:anyURI
[Term]
@@ -440577,6 +455799,9 @@
xref: MetaCyc:RXN-12236
xref: RHEA:46316
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:broadMatch EC:3.2.1.184
+property_value: skos:exactMatch MetaCyc:RXN-12236
+property_value: skos:exactMatch RHEA:46316
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -440664,6 +455889,9 @@
xref: MetaCyc:RXN-12319
xref: RHEA:31487
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.272
+property_value: skos:exactMatch RHEA:31487
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102241
@@ -440674,6 +455902,9 @@
xref: MetaCyc:RXN-12320
xref: RHEA:31491
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.273
+property_value: skos:exactMatch RHEA:31491
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102243
@@ -440683,8 +455914,10 @@
comment: The reason for obsoletion is that it more specific than the specificity of any known gene product.
synonym: "ATP:geranylgeraniol phosphotransferase activity" EXACT []
xref: RHEA:61664
+property_value: skos:exactMatch RHEA:61664
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16475" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
is_obsolete: true
replaced_by: GO:0052673
@@ -440696,7 +455929,9 @@
xref: MetaCyc:RXN-12332
xref: RHEA:30695
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch RHEA:30695
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102245
@@ -440707,6 +455942,9 @@
xref: MetaCyc:RXN-12338
xref: RHEA:31351
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.128
+property_value: skos:exactMatch RHEA:31351
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102246
@@ -440717,6 +455955,9 @@
xref: MetaCyc:RXN-12346
xref: RHEA:33079
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.2.30
+property_value: skos:exactMatch RHEA:33079
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102247
@@ -440763,6 +456004,9 @@
xref: MetaCyc:RXN-12393
xref: RHEA:26401
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.70
+property_value: skos:exactMatch RHEA:26401
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102252
@@ -440772,6 +456016,8 @@
xref: EC:3.2.1.176
xref: MetaCyc:RXN-12420
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.176
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102253
@@ -440853,7 +456099,10 @@
xref: MetaCyc:RXN-12450
xref: RHEA:31363
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.5.1.40
+property_value: skos:exactMatch RHEA:31363
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102262
@@ -440861,7 +456110,12 @@
namespace: molecular_function
def: "Catalysis of the reaction: a 5,6-dihydrouracil16 in tRNA + NAD(P) = H+ + a uracil16 in tRNA + NAD(P)H." [GOC:pz]
xref: MetaCyc:RXN-12454
+xref: RHEA:53376
+xref: RHEA:53380
is_a: GO:0017150 ! tRNA dihydrouridine synthase activity
+property_value: skos:broadMatch EC:1.3.1.88
+property_value: skos:narrowMatch RHEA:53376
+property_value: skos:narrowMatch RHEA:53380
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25028" xsd:anyURI
[Term]
@@ -440870,7 +456124,12 @@
namespace: molecular_function
def: "Catalysis of the reaction: a 5,6-dihydrouracil17 in tRNA + NAD(P) = H+ + a uracil17 in tRNA + NAD(P)H." [GOC:pz]
xref: MetaCyc:RXN-12455
+xref: RHEA:53368
+xref: RHEA:53372
is_a: GO:0017150 ! tRNA dihydrouridine synthase activity
+property_value: skos:broadMatch EC:1.3.1.88
+property_value: skos:narrowMatch RHEA:53368
+property_value: skos:narrowMatch RHEA:53372
[Term]
id: GO:0102264
@@ -440880,6 +456139,8 @@
xref: EC:1.3.1.91
xref: MetaCyc:RXN-12456
is_a: GO:0017150 ! tRNA dihydrouridine synthase activity
+property_value: skos:exactMatch EC:1.3.1.91
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102265
@@ -440889,6 +456150,8 @@
xref: EC:1.3.1.89
xref: MetaCyc:RXN-12457
is_a: GO:0017150 ! tRNA dihydrouridine synthase activity
+property_value: skos:exactMatch EC:1.3.1.89
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102266
@@ -440896,7 +456159,14 @@
namespace: molecular_function
def: "Catalysis of the reaction: a 5,6-dihydrouracil20a in tRNA + NAD(P) = H+ + a uracil20a in tRNA + NAD(P)H." [GOC:pz]
xref: EC:1.3.1.90
+xref: RHEA:53344
+xref: RHEA:53348
is_a: GO:0017150 ! tRNA dihydrouridine synthase activity
+property_value: skos:broadMatch MetaCyc:RXN-12475
+property_value: skos:exactMatch EC:1.3.1.90
+property_value: skos:narrowMatch RHEA:53344
+property_value: skos:narrowMatch RHEA:53348
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102267
@@ -440904,7 +456174,12 @@
namespace: molecular_function
def: "Catalysis of the reaction: a 5,6-dihydrouracil20b in tRNA + NAD(P) = H+ + a uracil20b in tRNA + NAD(P)H." [GOC:pz]
xref: MetaCyc:RXN-12476
+xref: RHEA:53352
+xref: RHEA:53356
is_a: GO:0017150 ! tRNA dihydrouridine synthase activity
+property_value: skos:broadMatch EC:1.3.1.90
+property_value: skos:narrowMatch RHEA:53352
+property_value: skos:narrowMatch RHEA:53356
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25028" xsd:anyURI
[Term]
@@ -440934,7 +456209,10 @@
xref: MetaCyc:RXN-12532
xref: RHEA:60448
is_a: GO:0004181 ! metallocarboxypeptidase activity
+property_value: skos:exactMatch EC:3.4.17.25
+property_value: skos:exactMatch RHEA:60448
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28557" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102275
@@ -440954,6 +456232,9 @@
xref: MetaCyc:RXN-12538
xref: RHEA:31523
is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
+property_value: skos:exactMatch EC:1.13.12.19
+property_value: skos:exactMatch RHEA:31523
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102277
@@ -440963,6 +456244,8 @@
xref: MetaCyc:RXN-12544
xref: RHEA:62164
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch RHEA:62164
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102278
@@ -441042,6 +456325,9 @@
xref: MetaCyc:RXN-12654
xref: RHEA:34635
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.170
+property_value: skos:exactMatch RHEA:34635
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102286
@@ -441070,6 +456356,9 @@
xref: MetaCyc:RXN-12680
xref: RHEA:31711
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.152
+property_value: skos:exactMatch MetaCyc:RXN-12680
+property_value: skos:exactMatch RHEA:31711
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -441120,7 +456409,9 @@
xref: MetaCyc:RXN-12693
xref: RHEA:35459
is_a: GO:0003854 ! 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity
+property_value: skos:exactMatch RHEA:35459
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27382" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102295
@@ -441139,7 +456430,10 @@
xref: EC:3.7.1.17
xref: MetaCyc:RXN-12718
xref: RHEA:32035
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.17
+property_value: skos:exactMatch RHEA:32035
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102297
@@ -441165,7 +456459,16 @@
namespace: molecular_function
def: "Catalysis of the reaction: (9Z,12Z,15Z)-octadecatrienoate + O2 = (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate. Also converts linoleate to (9R,10E,12Z)-9- hydroperoxyoctadeca-10,12-dienoate." [EC:1.13.11.61]
xref: EC:1.13.11.61
+xref: MetaCyc:RXN-12759
+xref: MetaCyc:RXN-12760
+xref: RHEA:31687
+xref: RHEA:31691
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.61
+property_value: skos:narrowMatch MetaCyc:RXN-12759
+property_value: skos:narrowMatch MetaCyc:RXN-12760
+property_value: skos:narrowMatch RHEA:31687
+property_value: skos:narrowMatch RHEA:31691
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -441197,6 +456500,9 @@
xref: MetaCyc:RXN-12801
xref: RHEA:31643
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.238
+property_value: skos:exactMatch RHEA:31643
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102303
@@ -441207,6 +456513,9 @@
xref: MetaCyc:RXN-12805
xref: RHEA:32103
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.240
+property_value: skos:exactMatch RHEA:32103
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102304
@@ -441217,6 +456526,9 @@
xref: MetaCyc:RXN-12838
xref: RHEA:31991
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.102
+property_value: skos:exactMatch RHEA:31991
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102305
@@ -441227,6 +456539,9 @@
xref: MetaCyc:RXN-12892
xref: RHEA:32075
is_a: GO:0016794 ! diphosphoric monoester hydrolase activity
+property_value: skos:exactMatch EC:3.1.7.10
+property_value: skos:exactMatch RHEA:32075
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102306
@@ -441245,7 +456560,16 @@
synonym: "erythromycin C 3''-o-methyltransferase activity" NARROW []
synonym: "erythromycin D 3''-o-methyltransferase activity" NARROW []
xref: EC:2.1.1.254
+xref: MetaCyc:RXN-12923
+xref: MetaCyc:RXN-12924
+xref: RHEA:32647
+xref: RHEA:32651
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.254
+property_value: skos:narrowMatch MetaCyc:RXN-12923
+property_value: skos:narrowMatch MetaCyc:RXN-12924
+property_value: skos:narrowMatch RHEA:32647
+property_value: skos:narrowMatch RHEA:32651
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -441284,6 +456608,9 @@
xref: MetaCyc:RXN-12961
xref: RHEA:32659
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.324
+property_value: skos:exactMatch RHEA:32659
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102312
@@ -441294,6 +456621,9 @@
xref: MetaCyc:RXN-12963
xref: RHEA:57868
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.62
+property_value: skos:exactMatch RHEA:57868
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102313
@@ -441304,6 +456634,9 @@
xref: MetaCyc:RXN-12980
xref: RHEA:32543
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.108
+property_value: skos:exactMatch RHEA:32543
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102317
@@ -441314,6 +456647,9 @@
xref: MetaCyc:RXN-13067
xref: RHEA:33907
is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.5.3.19
+property_value: skos:exactMatch RHEA:33907
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102318
@@ -441324,6 +456660,9 @@
xref: MetaCyc:RXN-13121
xref: RHEA:34063
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.284
+property_value: skos:exactMatch RHEA:34063
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102319
@@ -441334,6 +456673,9 @@
xref: MetaCyc:RXN-13122
xref: RHEA:33947
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.283
+property_value: skos:exactMatch RHEA:33947
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102320
@@ -441344,6 +456686,9 @@
xref: MetaCyc:RXN-4342
xref: RHEA:32895
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.56
+property_value: skos:exactMatch RHEA:32895
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102321
@@ -441363,6 +456708,8 @@
xref: MetaCyc:RXN-13151
xref: RHEA:63524
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:63524
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102323
@@ -441372,6 +456719,8 @@
xref: MetaCyc:RXN-13152
xref: RHEA:63520
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:63520
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102324
@@ -441391,6 +456740,8 @@
xref: MetaCyc:RXN-13169
xref: RHEA:63516
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:63516
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102326
@@ -441476,6 +456827,9 @@
xref: MetaCyc:RXN-13269
xref: RHEA:34515
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.36
+property_value: skos:exactMatch RHEA:34515
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102335
@@ -441486,6 +456840,9 @@
xref: MetaCyc:RXN-13274
xref: RHEA:34511
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.290
+property_value: skos:exactMatch RHEA:34511
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102336
@@ -441665,6 +457022,7 @@
xref: MetaCyc:RXN-13363
xref: RHEA:54912
is_a: GO:0008106 ! alcohol dehydrogenase (NADP+) activity
+property_value: skos:exactMatch RHEA:54912
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30275" xsd:anyURI
[Term]
@@ -441676,6 +457034,9 @@
xref: MetaCyc:RXN-13371
xref: RHEA:33967
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.91
+property_value: skos:exactMatch RHEA:33967
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102356
@@ -441693,6 +457054,7 @@
def: "Catalysis of the reaction: mithramycin DK + NADPH + H+ = iso-mithramycin + NADP+. Note that iso-mithramycin (iso-MTM) is a C2-epimer of mithramycin. This intermediate appears to be biologically important because it is non-toxic, then exported out of the cell and finally spontaneously epimerized into the toxic mithramycin. This could represent a self-resistance mechanism against MTM toxicity." [PMID:31702856]
xref: MetaCyc:RXN-13385
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30329" xsd:anyURI
[Term]
@@ -441703,6 +457065,8 @@
xref: MetaCyc:RXN-13448
xref: RHEA:68960
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13448
+property_value: skos:exactMatch RHEA:68960
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -441760,7 +457124,16 @@
def: "Catalysis of the reaction: taxusin + NADPH + O2 + H+ = 2-alpha-hydroxytaxusin + NADP + H2O. Also converts 7beta-hydroxytaxusin to 2alpha,7beta-dihydroxytaxusin." [EC:1.14.14.183, PMID:15178487]
synonym: "taxusin 2-alpha-hydroxylase activity" EXACT []
xref: EC:1.14.14.183
+xref: MetaCyc:RXN-13486
+xref: MetaCyc:RXN-13487
+xref: RHEA:71399
+xref: RHEA:71407
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.183
+property_value: skos:narrowMatch MetaCyc:RXN-13486
+property_value: skos:narrowMatch MetaCyc:RXN-13487
+property_value: skos:narrowMatch RHEA:71399
+property_value: skos:narrowMatch RHEA:71407
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28220" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -441840,6 +457213,9 @@
xref: MetaCyc:RXN-13509
xref: RHEA:43068
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.126
+property_value: skos:exactMatch MetaCyc:RXN-13509
+property_value: skos:exactMatch RHEA:43068
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -441862,6 +457238,9 @@
xref: MetaCyc:RXN-13506
xref: RHEA:35499
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.115
+property_value: skos:exactMatch RHEA:35499
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102376
@@ -441880,6 +457259,8 @@
xref: MetaCyc:RXN-13511
xref: RHEA:61732
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13511
+property_value: skos:exactMatch RHEA:61732
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -441890,6 +457271,8 @@
xref: MetaCyc:RXN-13512
xref: RHEA:61736
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13512
+property_value: skos:exactMatch RHEA:61736
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -441900,6 +457283,8 @@
xref: MetaCyc:RXN-13514
xref: RHEA:61744
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13514
+property_value: skos:exactMatch RHEA:61744
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -441910,6 +457295,8 @@
xref: MetaCyc:RXN-13516
xref: RHEA:61752
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13516
+property_value: skos:exactMatch RHEA:61752
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -441920,6 +457307,8 @@
xref: MetaCyc:RXN-13517
xref: RHEA:61756
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13517
+property_value: skos:exactMatch RHEA:61756
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -441930,6 +457319,8 @@
xref: MetaCyc:RXN-13518
xref: RHEA:61760
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13518
+property_value: skos:exactMatch RHEA:61760
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -441967,6 +457358,7 @@
xref: MetaCyc:RXN-13536
xref: RHEA:63736
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:63736
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30249" xsd:anyURI
[Term]
@@ -441988,6 +457380,9 @@
xref: MetaCyc:RXN-13574
xref: RHEA:34491
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.184
+property_value: skos:exactMatch RHEA:34491
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102389
@@ -441996,7 +457391,9 @@
def: "Catalysis of the reaction: NADP + a ditrans,polycis-dolichol = NADPH + H+ + a di-trans, poly-cis-polyprenol." [GOC:pz, RHEA:34279]
xref: RHEA:34279
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:34279
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28566" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102390
@@ -442007,6 +457404,9 @@
xref: MetaCyc:RXN-13605
xref: RHEA:34179
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.93
+property_value: skos:exactMatch RHEA:34179
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102391
@@ -442016,7 +457416,9 @@
xref: MetaCyc:RXN-13614
xref: RHEA:33627
is_a: GO:0031956 ! medium-chain fatty acid-CoA ligase activity
+property_value: skos:exactMatch RHEA:33627
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18967" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102392
@@ -442055,6 +457457,9 @@
xref: MetaCyc:RXN-13642
xref: RHEA:34399
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.68
+property_value: skos:exactMatch RHEA:34399
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102396
@@ -442065,6 +457470,9 @@
xref: MetaCyc:RXN-13643
xref: RHEA:34403
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.69
+property_value: skos:exactMatch RHEA:34403
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102398
@@ -442121,6 +457529,8 @@
xref: MetaCyc:RXN-13718
xref: RHEA:61116
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:61116
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102406
@@ -442131,6 +457541,9 @@
xref: MetaCyc:RXN-13728
xref: RHEA:26470
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.188
+property_value: skos:exactMatch RHEA:26470
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102407
@@ -442189,6 +457602,9 @@
xref: MetaCyc:RXN-13769
xref: RHEA:34467
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.139
+property_value: skos:exactMatch RHEA:34467
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102413
@@ -442198,6 +457614,8 @@
xref: MetaCyc:RXN-13791
xref: RHEA:78891
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch MetaCyc:RXN-13791
+property_value: skos:exactMatch RHEA:78891
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -442356,8 +457774,17 @@
synonym: "alpha-linolenate delta5 desaturase activity" NARROW []
synonym: "linoleate delta5 desaturase activity" RELATED []
xref: EC:1.14.19.12
+xref: MetaCyc:RXN-13857
+xref: MetaCyc:RXN-13858
+xref: RHEA:38039
+xref: RHEA:46236
is_a: GO:0004497 ! monooxygenase activity
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.12
+property_value: skos:narrowMatch MetaCyc:RXN-13857
+property_value: skos:narrowMatch MetaCyc:RXN-13858
+property_value: skos:narrowMatch RHEA:38039
+property_value: skos:narrowMatch RHEA:46236
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24100" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -442369,6 +457796,8 @@
xref: MetaCyc:RXN-13906
xref: RHEA:73115
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13906
+property_value: skos:exactMatch RHEA:73115
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442397,6 +457826,8 @@
xref: MetaCyc:RXN-13910
xref: RHEA:74719
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13910
+property_value: skos:exactMatch RHEA:74719
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442425,6 +457856,8 @@
xref: MetaCyc:RXN-13916
xref: RHEA:74739
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13916
+property_value: skos:exactMatch RHEA:74739
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442435,6 +457868,8 @@
xref: MetaCyc:RXN-13918
xref: RHEA:74771
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13918
+property_value: skos:exactMatch RHEA:74771
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442445,6 +457880,8 @@
xref: MetaCyc:RXN-13919
xref: RHEA:74735
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13919
+property_value: skos:exactMatch RHEA:74735
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442455,6 +457892,8 @@
xref: MetaCyc:RXN-13920
xref: RHEA:74767
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13920
+property_value: skos:exactMatch RHEA:74767
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442466,6 +457905,9 @@
xref: MetaCyc:RXN-13927
xref: RHEA:34555
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.337
+property_value: skos:exactMatch RHEA:34555
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102444
@@ -442475,6 +457917,8 @@
xref: MetaCyc:RXN-13929
xref: RHEA:74759
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13929
+property_value: skos:exactMatch RHEA:74759
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442485,6 +457929,8 @@
xref: MetaCyc:RXN-13930
xref: RHEA:74715
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13930
+property_value: skos:exactMatch RHEA:74715
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442495,6 +457941,8 @@
xref: MetaCyc:RXN-13932
xref: RHEA:74763
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13932
+property_value: skos:exactMatch RHEA:74763
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442505,6 +457953,8 @@
xref: MetaCyc:RXN-13933
xref: RHEA:73271
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13933
+property_value: skos:exactMatch RHEA:73271
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442515,6 +457965,8 @@
xref: MetaCyc:RXN-13934
xref: RHEA:74731
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13934
+property_value: skos:exactMatch RHEA:74731
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442525,6 +457977,8 @@
xref: MetaCyc:RXN-13935
xref: RHEA:74743
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13935
+property_value: skos:exactMatch RHEA:74743
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442535,6 +457989,8 @@
xref: MetaCyc:RXN-13936
xref: RHEA:74775
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13936
+property_value: skos:exactMatch RHEA:74775
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442545,6 +458001,8 @@
xref: MetaCyc:RXN-13937
xref: RHEA:74755
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-13937
+property_value: skos:exactMatch RHEA:74755
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -442556,6 +458014,9 @@
xref: MetaCyc:RXN-13958
xref: RHEA:34803
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.211
+property_value: skos:exactMatch RHEA:34803
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102453
@@ -442566,6 +458027,9 @@
xref: MetaCyc:RXN-13959
xref: RHEA:35411
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.215
+property_value: skos:exactMatch RHEA:35411
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102454
@@ -442576,6 +458040,9 @@
xref: MetaCyc:RXN-13960
xref: RHEA:35631
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.294
+property_value: skos:exactMatch RHEA:35631
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102455
@@ -442586,6 +458053,9 @@
xref: MetaCyc:RXN-13965
xref: RHEA:35419
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.297
+property_value: skos:exactMatch RHEA:35419
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102456
@@ -442607,6 +458077,9 @@
xref: MetaCyc:RXN-13969
xref: RHEA:35431
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.300
+property_value: skos:exactMatch RHEA:35431
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102458
@@ -442697,6 +458170,8 @@
xref: MetaCyc:RXN-14058
xref: RHEA:28318
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:broadMatch EC:2.4.1.253
+property_value: skos:exactMatch RHEA:28318
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -442707,6 +458182,8 @@
xref: MetaCyc:RXN-14060
xref: RHEA:28322
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:broadMatch EC:2.4.1.253
+property_value: skos:exactMatch RHEA:28322
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -442717,6 +458194,8 @@
xref: MetaCyc:RXN-14069
xref: RHEA:57588
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch MetaCyc:RXN-14069
+property_value: skos:exactMatch RHEA:57588
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -442805,6 +458284,9 @@
xref: MetaCyc:RXN-14089
xref: RHEA:36051
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.185
+property_value: skos:exactMatch RHEA:36051
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102479
@@ -442834,7 +458316,10 @@
xref: EC:3.7.1.22
xref: MetaCyc:RXN-14149
xref: RHEA:25836
-is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
+is_a: GO:0016823 ! hydrolase activity, acting on carbon-carbon bonds, in ketonic substances
+property_value: skos:exactMatch EC:3.7.1.22
+property_value: skos:exactMatch RHEA:25836
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102482
@@ -442845,6 +458330,9 @@
xref: MetaCyc:RXN-14150
xref: RHEA:25840
is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses
+property_value: skos:exactMatch EC:5.3.1.30
+property_value: skos:exactMatch RHEA:25840
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102483
@@ -442993,6 +458481,9 @@
xref: MetaCyc:RXN-14347
xref: RHEA:39063
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.371
+property_value: skos:exactMatch RHEA:39063
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102498
@@ -443070,7 +458561,10 @@
xref: MetaCyc:RXN-13967
xref: RHEA:35427
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.299
+property_value: skos:exactMatch RHEA:35427
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102507
@@ -443178,7 +458672,9 @@
xref: MetaCyc:RXN-14487
xref: RHEA:55956
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:55956
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28851" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102518
@@ -443209,6 +458705,9 @@
xref: RHEA:36347
is_a: GO:0016833 ! oxo-acid-lyase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:4.1.3.44
+property_value: skos:exactMatch RHEA:36347
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102522
@@ -443220,6 +458719,9 @@
xref: RHEA:36355
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.5.1.114
+property_value: skos:exactMatch RHEA:36355
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102523
@@ -443230,6 +458732,9 @@
xref: MetaCyc:RXN-14536
xref: RHEA:36591
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.103
+property_value: skos:exactMatch RHEA:36591
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102524
@@ -443242,6 +458747,9 @@
xref: RHEA:37899
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:1.14.11.42
+property_value: skos:exactMatch RHEA:37899
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102525
@@ -443252,6 +458760,9 @@
xref: MetaCyc:RXN-14542
xref: RHEA:36607
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.41
+property_value: skos:exactMatch RHEA:36607
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102526
@@ -443262,6 +458773,9 @@
xref: MetaCyc:RXN-14543
xref: RHEA:36651
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.284
+property_value: skos:exactMatch RHEA:36651
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102527
@@ -443272,6 +458786,9 @@
xref: MetaCyc:RXN-14547
xref: RHEA:36699
is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity
+property_value: skos:exactMatch EC:6.3.1.15
+property_value: skos:exactMatch RHEA:36699
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102528
@@ -443290,6 +458807,8 @@
xref: MetaCyc:RXN-14661
xref: RHEA:73071
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-14661
+property_value: skos:exactMatch RHEA:73071
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -443299,9 +458818,17 @@
def: "Catalysis of the reaction: aclacinomycin T(1+) + H2O = 15-demethylaclacinomycin T + methanol + H+." [EC:3.1.1.95, GOC:pz]
xref: EC:3.1.1.95
xref: MetaCyc:RXN-14703
+xref: MetaCyc:RXN-14863
+xref: MetaCyc:RXN-14865
xref: RHEA:37891
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.95
+property_value: skos:exactMatch MetaCyc:RXN-14703
+property_value: skos:exactMatch RHEA:37891
+property_value: skos:narrowMatch MetaCyc:RXN-14863
+property_value: skos:narrowMatch MetaCyc:RXN-14865
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27860" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102531
@@ -443310,7 +458837,16 @@
def: "Catalysis of the reaction: H2O + an ecdysteroid 22-phosphate = phosphate + an ecdysteroid. Also has activity towards other ecdysteriod phosphates including 20-hydroxyecdysone 22-phosphate (20E22P) and 2-deoxyecdysone 22-phosphate (2dE22P)." [MetaCyc:RXN-14734, PMID:12721294]
synonym: "ecdysone-phosphate phosphatase activity" NARROW []
xref: MetaCyc:RXN-14734
+xref: MetaCyc:RXN-14766
+xref: RHEA:63576
+xref: RHEA:63580
+xref: RHEA:63584
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch MetaCyc:RXN-14734
+property_value: skos:narrowMatch MetaCyc:RXN-14766
+property_value: skos:narrowMatch RHEA:63576
+property_value: skos:narrowMatch RHEA:63580
+property_value: skos:narrowMatch RHEA:63584
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28862" xsd:anyURI
[Term]
@@ -443321,6 +458857,8 @@
xref: MetaCyc:RXN-14748
xref: RHEA:73427
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch MetaCyc:RXN-14748
+property_value: skos:exactMatch RHEA:73427
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -443331,6 +458869,8 @@
xref: MetaCyc:RXN-14750
xref: RHEA:73263
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-14750
+property_value: skos:exactMatch RHEA:73263
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -443341,6 +458881,8 @@
xref: MetaCyc:RXN-14751
xref: RHEA:73435
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch MetaCyc:RXN-14751
+property_value: skos:exactMatch RHEA:73435
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -443351,6 +458893,8 @@
xref: MetaCyc:RXN-14752
xref: RHEA:73247
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-14752
+property_value: skos:exactMatch RHEA:73247
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -443361,6 +458905,8 @@
xref: MetaCyc:RXN-14754
xref: RHEA:73431
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch MetaCyc:RXN-14754
+property_value: skos:exactMatch RHEA:73431
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -443377,9 +458923,17 @@
id: GO:0102538
name: UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase activity
namespace: molecular_function
-def: "Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H." [GOC:pz, PMID:10627048, PMID:24817117]
+def: "Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H." [EC:1.1.1.426, PMID:10627048, PMID:24817117]
+xref: EC:1.1.1.426
xref: MetaCyc:RXN-14767
+xref: RHEA:68552
+xref: RHEA:68556
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.426
+property_value: skos:exactMatch MetaCyc:RXN-14767
+property_value: skos:narrowMatch RHEA:68552
+property_value: skos:narrowMatch RHEA:68556
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0102539
@@ -443439,14 +458993,21 @@
[Term]
id: GO:0102545
-name: phospholipase B activity
+name: B-type glycerophospholipase activity
namespace: molecular_function
-def: "Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + 2 H2O = sn-glycerol 3-phosphocholine + 2 a carboxylate + 2 H+." [RHEA:32907]
+def: "A glycerophospholipase activity that cleaves both fatty acisd attached to the sn-1 and the sn-2 position of the glycerol group of a glycerophospholipid. Substrates include phosphatidylcholine and phosphatidylethanolamine." [PMID:30109646]
+synonym: "B-type phospholipase activity" EXACT []
synonym: "phosphatidyl phospholipase B activity" EXACT []
+synonym: "phospholipase B activity" EXACT []
xref: MetaCyc:RXN-14899
xref: RHEA:32907
-is_a: GO:0004620 ! phospholipase activity
+is_a: GO:0004620 ! glycerophospholipase activity
+is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:narrowMatch RHEA:32907
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27557" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30258" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31049" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31198" xsd:anyURI
[Term]
id: GO:0102546
@@ -443457,6 +459018,9 @@
xref: MetaCyc:RXN-14900
xref: RHEA:58456
is_a: GO:0016803 ! ether hydrolase activity
+property_value: skos:exactMatch EC:3.2.1.170
+property_value: skos:exactMatch MetaCyc:RXN-14900
+property_value: skos:exactMatch RHEA:58456
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -443468,6 +459032,9 @@
xref: MetaCyc:RXN-14901
xref: RHEA:32059
is_a: GO:0016803 ! ether hydrolase activity
+property_value: skos:exactMatch EC:3.2.1.208
+property_value: skos:exactMatch MetaCyc:RXN-14901
+property_value: skos:exactMatch RHEA:32059
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -443489,6 +459056,9 @@
xref: MetaCyc:RXN-14917
xref: RHEA:38007
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.295
+property_value: skos:exactMatch RHEA:38007
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102551
@@ -443540,6 +459110,9 @@
xref: MetaCyc:RXN-14975
xref: RHEA:38579
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.120
+property_value: skos:exactMatch RHEA:38579
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102557
@@ -443550,6 +459123,9 @@
xref: MetaCyc:RXN-14978
xref: RHEA:22272
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.121
+property_value: skos:exactMatch RHEA:22272
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102559
@@ -443561,6 +459137,8 @@
xref: MetaCyc:RXN-14992
xref: RHEA:42896
is_a: GO:0036009 ! protein-glutamine N-methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.297
+property_value: skos:exactMatch RHEA:42896
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29860" xsd:anyURI
[Term]
@@ -443583,7 +459161,12 @@
synonym: "D-ribose 2,5-bisphosphate 2-phosphohydrolase activity" RELATED []
xref: EC:3.1.4.57
xref: MetaCyc:RXN-14996
+xref: RHEA:41612
+xref: RHEA:41616
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.57
+property_value: skos:narrowMatch RHEA:41612
+property_value: skos:narrowMatch RHEA:41616
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -443649,9 +459232,15 @@
def: "Catalysis of the reaction: 3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl/L-threonyl-[protein] + H2O = L-seryl//L-threonyl-[protein] + N-acetyl-D-glucosamine." [EC:3.2.1.169]
xref: EC:3.2.1.169
xref: MetaCyc:RXN-15215
+xref: RHEA:48876
+xref: RHEA:48892
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:3.2.1.169
+property_value: skos:narrowMatch RHEA:48876
+property_value: skos:narrowMatch RHEA:48892
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27560" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102572
@@ -443661,6 +459250,8 @@
xref: MetaCyc:RXN-15251
xref: RHEA:50684
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch RHEA:50684
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102573
@@ -443671,6 +459262,9 @@
xref: MetaCyc:RXN-15264
xref: RHEA:33075
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.120
+property_value: skos:exactMatch RHEA:33075
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102574
@@ -443721,6 +459315,9 @@
xref: MetaCyc:RXN-15326
xref: RHEA:35443
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.51
+property_value: skos:exactMatch RHEA:35443
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102581
@@ -443767,6 +459364,8 @@
xref: MetaCyc:RXN-15331
xref: RHEA:72871
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch MetaCyc:RXN-15331
+property_value: skos:exactMatch RHEA:72871
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -443869,6 +459468,9 @@
xref: MetaCyc:RXN-15379
xref: RHEA:41464
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.70
+property_value: skos:exactMatch RHEA:41464
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102597
@@ -443879,6 +459481,9 @@
xref: MetaCyc:RXN-15381
xref: RHEA:41468
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.122
+property_value: skos:exactMatch RHEA:41468
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102598
@@ -443889,6 +459494,9 @@
xref: MetaCyc:RXN-15382
xref: RHEA:41472
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.123
+property_value: skos:exactMatch RHEA:41472
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102599
@@ -443916,8 +459524,14 @@
synonym: "cytochrome P450 dependent beta-amyrin 16beta-hydroxylase activity" EXACT []
xref: EC:1.14.14.63
xref: MetaCyc:RXN-15385
+xref: RHEA:55440
+xref: RHEA:55444
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.63
+property_value: skos:narrowMatch RHEA:55440
+property_value: skos:narrowMatch RHEA:55444
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28011" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102602
@@ -444005,6 +459619,8 @@
xref: MetaCyc:RXN-15454
xref: RHEA:48992
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:48992
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102614
@@ -444015,6 +459631,9 @@
xref: MetaCyc:RXN-15460
xref: RHEA:57964
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.168
+property_value: skos:exactMatch MetaCyc:RXN-15460
+property_value: skos:exactMatch RHEA:57964
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -444101,6 +459720,8 @@
xref: MetaCyc:RXN-15528
xref: RHEA:73243
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-15528
+property_value: skos:exactMatch RHEA:73243
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -444111,6 +459732,8 @@
xref: MetaCyc:RXN-15529
xref: RHEA:73239
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-15529
+property_value: skos:exactMatch RHEA:73239
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -444121,6 +459744,8 @@
xref: MetaCyc:RXN-15530
xref: RHEA:73251
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch MetaCyc:RXN-15530
+property_value: skos:exactMatch RHEA:73251
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -444131,7 +459756,9 @@
xref: MetaCyc:RXN-15531
xref: RHEA:61320
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:61320
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102627
@@ -444141,6 +459768,8 @@
xref: MetaCyc:RXN-15532
xref: RHEA:61328
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch MetaCyc:RXN-15532
+property_value: skos:exactMatch RHEA:61328
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -444188,7 +459817,10 @@
xref: MetaCyc:RXN-15538
xref: RHEA:50364
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.73
+property_value: skos:exactMatch RHEA:50364
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
[Term]
@@ -444216,6 +459848,8 @@
xref: MetaCyc:RXN-15607
xref: RHEA:47716
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:47716
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102636
@@ -444374,8 +460008,17 @@
synonym: "1-18:1-2-16:0-phosphatidylglycerol trans-3 desaturase activity" RELATED []
xref: EC:1.14.19.43
xref: MetaCyc:RXN-16053
+xref: MetaCyc:RXN-1725
+xref: MetaCyc:RXN-8318
+xref: MetaCyc:RXN-8319
xref: RHEA:46764
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.43
+property_value: skos:exactMatch MetaCyc:RXN-16053
+property_value: skos:exactMatch RHEA:46764
+property_value: skos:narrowMatch MetaCyc:RXN-1725
+property_value: skos:narrowMatch MetaCyc:RXN-8318
+property_value: skos:narrowMatch MetaCyc:RXN-8319
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28362" xsd:anyURI
@@ -444525,6 +460168,9 @@
xref: MetaCyc:RXN-3624
xref: RHEA:31371
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.212
+property_value: skos:exactMatch RHEA:31371
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102671
@@ -444535,6 +460181,9 @@
xref: MetaCyc:RXN-4002
xref: RHEA:35471
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.270
+property_value: skos:exactMatch RHEA:35471
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102672
@@ -444546,6 +460195,9 @@
xref: MetaCyc:RXN-4121
xref: RHEA:63508
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.92
+property_value: skos:exactMatch MetaCyc:RXN-4121
+property_value: skos:exactMatch RHEA:63508
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -444557,6 +460209,7 @@
xref: MetaCyc:RXN-4142
xref: RHEA:49832
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch RHEA:49832
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28142" xsd:anyURI
[Term]
@@ -444642,7 +460295,10 @@
xref: MetaCyc:RXN-4313
xref: RHEA:48560
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.2.n1
+property_value: skos:exactMatch RHEA:48560
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26539" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102684
@@ -444653,6 +460309,9 @@
xref: MetaCyc:RXN-4602
xref: RHEA:33263
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.40
+property_value: skos:exactMatch RHEA:33263
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102685
@@ -444780,6 +460439,9 @@
xref: MetaCyc:RXN-4781
xref: RHEA:28635
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.61
+property_value: skos:exactMatch RHEA:28635
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102699
@@ -444808,6 +460470,9 @@
xref: MetaCyc:RXN-5121
xref: RHEA:32687
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.105
+property_value: skos:exactMatch RHEA:32687
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102702
@@ -444826,6 +460491,9 @@
xref: MetaCyc:RXN-5142
xref: RHEA:25484
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.117
+property_value: skos:exactMatch RHEA:25484
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102704
@@ -444837,8 +460505,11 @@
xref: RHEA:29519
is_a: GO:0000009 ! alpha-1,6-mannosyltransferase activity
is_a: GO:0120562 ! GlcNAc(2)-PP-Dol mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.257
+property_value: skos:exactMatch RHEA:29519
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22675" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24984" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30326" xsd:anyURI
[Term]
@@ -444849,6 +460520,8 @@
xref: MetaCyc:RXN-5641
xref: RHEA:45824
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch RHEA:45824
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102706
@@ -444897,6 +460570,9 @@
xref: MetaCyc:RXN-6501
xref: RHEA:26188
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.250
+property_value: skos:exactMatch RHEA:26188
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102711
@@ -444973,6 +460649,9 @@
xref: MetaCyc:RXN-6685
xref: RHEA:32115
is_a: GO:0050498 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated
+property_value: skos:exactMatch EC:1.14.11.59
+property_value: skos:exactMatch RHEA:32115
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102718
@@ -444983,6 +460662,9 @@
xref: MetaCyc:RXN-6687
xref: RHEA:32099
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.241
+property_value: skos:exactMatch RHEA:32099
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102719
@@ -445000,7 +460682,14 @@
namespace: molecular_function
def: "Catalysis of the reaction: acetyl-CoA + benzyl alcohol = benzyl acetate + CoA. Also converts (E)-cinnamyl alcohol into (E)-cinnamyl acetate." [EC:2.3.1.224]
xref: EC:2.3.1.224
+xref: MetaCyc:RXN-6762
+xref: RHEA:36147
+xref: RHEA:36151
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.224
+property_value: skos:narrowMatch MetaCyc:RXN-6762
+property_value: skos:narrowMatch RHEA:36147
+property_value: skos:narrowMatch RHEA:36151
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -445012,6 +460701,9 @@
xref: MetaCyc:RXN-6883
xref: RHEA:30255
is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.10.3.11
+property_value: skos:exactMatch RHEA:30255
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102722
@@ -445058,6 +460750,9 @@
xref: MetaCyc:RXN-7082
xref: RHEA:33975
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.182
+property_value: skos:exactMatch RHEA:33975
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102727
@@ -445105,6 +460800,7 @@
synonym: "D-myo-inositol (1,3,4,6)-tetrakisphosphate 2-kinase activity" EXACT []
xref: MetaCyc:RXN-7185
is_a: GO:0051765 ! inositol tetrakisphosphate kinase activity
+property_value: skos:exactMatch MetaCyc:RXN-7185
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
[Term]
@@ -445117,6 +460813,8 @@
synonym: "inositol-pentakisphosphate 5-kinase activity" BROAD []
xref: MetaCyc:RXN-7186
is_a: GO:0120517 ! inositol pentakisphosphate kinase activity
+property_value: skos:broadMatch EC:2.7.1.140
+property_value: skos:exactMatch MetaCyc:RXN-7186
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28385" xsd:anyURI
[Term]
@@ -445135,7 +460833,15 @@
def: "Catalysis of the reaction: castasterone + O2 + reduced [NADPH--hemoprotein reductase] = brassinolide + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. Broad specificity for several brassinosteroids, including castasterone, teasterone, and typhasterol." [EC:1.14.14.180]
xref: EC:1.14.14.180
xref: MetaCyc:RXN-720
+xref: RHEA:69923
+xref: RHEA:70015
+xref: RHEA:70019
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.180
+property_value: skos:exactMatch MetaCyc:RXN-720
+property_value: skos:narrowMatch RHEA:69923
+property_value: skos:narrowMatch RHEA:70015
+property_value: skos:narrowMatch RHEA:70019
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -445147,6 +460853,9 @@
xref: MetaCyc:RXN-7481
xref: RHEA:35143
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.220
+property_value: skos:exactMatch RHEA:35143
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102737
@@ -445197,7 +460906,18 @@
synonym: "paraxanthine:S-adenosyl-L-methionine 3-N-methyltransferase activity" NARROW []
synonym: "theobromine:S-adenosyl-L-methionine 1-N-methyltransferase activity" NARROW []
xref: EC:2.1.1.160
+xref: MetaCyc:RXN-7599
+xref: MetaCyc:RXN-7601
+xref: RHEA:10280
+xref: RHEA:20944
+xref: RHEA:24604
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.160
+property_value: skos:narrowMatch MetaCyc:RXN-7599
+property_value: skos:narrowMatch MetaCyc:RXN-7601
+property_value: skos:narrowMatch RHEA:10280
+property_value: skos:narrowMatch RHEA:20944
+property_value: skos:narrowMatch RHEA:24604
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -445350,6 +461070,8 @@
xref: MetaCyc:RXN-7703
xref: RHEA:60664
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.108
+property_value: skos:exactMatch RHEA:60664
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -445361,8 +461083,11 @@
xref: MetaCyc:RXN-7711
xref: RHEA:14473
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.93
+property_value: skos:exactMatch RHEA:14473
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25304" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25805" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102759
@@ -445392,6 +461117,8 @@
xref: MetaCyc:RXN-7753
xref: RHEA:60948
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch RHEA:60948
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102762
@@ -445409,7 +461136,9 @@
xref: MetaCyc:RXN-7763
xref: RHEA:38099
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
+property_value: skos:exactMatch RHEA:38099
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102764
@@ -445428,7 +461157,9 @@
xref: MetaCyc:RXN-7770
xref: RHEA:70523
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch RHEA:70523
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30235" xsd:anyURI
[Term]
@@ -445440,6 +461171,9 @@
xref: MetaCyc:RXN-7773
xref: RHEA:31539
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.232
+property_value: skos:exactMatch RHEA:31539
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102767
@@ -445450,7 +461184,10 @@
xref: MetaCyc:RXN-12719
xref: RHEA:31743
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.231
+property_value: skos:exactMatch RHEA:31743
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102768
@@ -445478,6 +461215,7 @@
def: "Catalysis of the reaction: an L-1-phosphatidyl-inositol + a dihydroceramide = an inositol phosphodihydroceramide + a 1,2-diacyl-sn-glycerol." [MetaCyc:RXN-7795]
xref: MetaCyc:RXN-7795
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch MetaCyc:RXN-7795
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -445491,6 +461229,9 @@
xref: MetaCyc:RXN-7796
xref: RHEA:46512
is_a: GO:0080132 ! fatty acid 2-hydroxylase activity
+property_value: skos:exactMatch EC:1.14.18.7
+property_value: skos:exactMatch MetaCyc:RXN-7796
+property_value: skos:exactMatch RHEA:46512
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27540" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27541" xsd:anyURI
@@ -445502,10 +461243,12 @@
synonym: "sphingolipid long-chain base 4-hydroxylase activity" RELATED []
xref: EC:1.14.18.5
xref: MetaCyc:RXN-14250
-xref: Reactome:R-HSA-428260 "DEGS2 oxygenates dihydroceramide"
xref: RHEA:55808
is_a: GO:0016716 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.18.5
+property_value: skos:exactMatch RHEA:55808
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25981" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102773
@@ -445563,6 +461306,9 @@
xref: MetaCyc:RXN-7854
xref: RHEA:34135
is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
+property_value: skos:exactMatch EC:1.21.3.7
+property_value: skos:exactMatch RHEA:34135
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102779
@@ -445573,6 +461319,9 @@
xref: MetaCyc:RXN-7855
xref: RHEA:34411
is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
+property_value: skos:exactMatch EC:1.21.3.8
+property_value: skos:exactMatch RHEA:34411
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102780
@@ -445703,6 +461452,9 @@
xref: MetaCyc:RXN-8086
xref: RHEA:31475
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.262
+property_value: skos:exactMatch RHEA:31475
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102794
@@ -445782,6 +461534,9 @@
xref: MetaCyc:RXN-8139
xref: RHEA:35515
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.214
+property_value: skos:exactMatch RHEA:35515
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102802
@@ -445792,6 +461547,9 @@
xref: MetaCyc:RXN-8147
xref: RHEA:27477
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.31
+property_value: skos:exactMatch MetaCyc:RXN-8147
+property_value: skos:exactMatch RHEA:27477
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -445822,7 +461580,12 @@
xref: EC:1.14.11.32
xref: MetaCyc:RXN-8152
xref: RHEA:27413
+xref: RHEA:75955
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.32
+property_value: skos:exactMatch RHEA:27413
+property_value: skos:narrowMatch RHEA:75955
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102806
@@ -445869,7 +461632,10 @@
xref: MetaCyc:RXN-8182
xref: RHEA:57832
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.20
+property_value: skos:exactMatch RHEA:57832
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25447" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102811
@@ -445880,6 +461646,9 @@
xref: MetaCyc:RXN-8197
xref: RHEA:32495
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.83
+property_value: skos:exactMatch RHEA:32495
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102812
@@ -445927,6 +461696,9 @@
xref: MetaCyc:RXN-8234
xref: RHEA:35423
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.298
+property_value: skos:exactMatch RHEA:35423
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102817
@@ -445985,6 +461757,9 @@
xref: RHEA:55332
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.267
+property_value: skos:exactMatch EC:2.1.1.42
+property_value: skos:exactMatch RHEA:55332
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -446180,8 +461955,17 @@
synonym: "1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity (SN2-16:1 forming)" EXACT []
xref: EC:1.14.19.42
xref: MetaCyc:RXN-16048
+xref: MetaCyc:RXN-1728
+xref: MetaCyc:RXN-8304
+xref: MetaCyc:RXN-8307
xref: RHEA:46756
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.42
+property_value: skos:exactMatch MetaCyc:RXN-16048
+property_value: skos:exactMatch RHEA:46756
+property_value: skos:narrowMatch MetaCyc:RXN-1728
+property_value: skos:narrowMatch MetaCyc:RXN-8304
+property_value: skos:narrowMatch MetaCyc:RXN-8307
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28363" xsd:anyURI
@@ -446251,8 +462035,28 @@
def: "Catalysis of the reaction: a (9Z)-octadecenoyl-containing glycerolipid + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]." [RHEA:46376]
synonym: "1-18:1-2-16:0-phosphatidylglycerol omega-6 desaturase activity" EXACT []
xref: EC:1.14.19.23
+xref: MetaCyc:RXN-1726
+xref: MetaCyc:RXN-8294
+xref: MetaCyc:RXN-8296
+xref: MetaCyc:RXN-8298
+xref: MetaCyc:RXN-8302
+xref: MetaCyc:RXN-8305
+xref: MetaCyc:RXN-8308
+xref: MetaCyc:RXN-8316
+xref: MetaCyc:RXN-8363
xref: RHEA:46376
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.23
+property_value: skos:exactMatch RHEA:46376
+property_value: skos:narrowMatch MetaCyc:RXN-1726
+property_value: skos:narrowMatch MetaCyc:RXN-8294
+property_value: skos:narrowMatch MetaCyc:RXN-8296
+property_value: skos:narrowMatch MetaCyc:RXN-8298
+property_value: skos:narrowMatch MetaCyc:RXN-8302
+property_value: skos:narrowMatch MetaCyc:RXN-8305
+property_value: skos:narrowMatch MetaCyc:RXN-8308
+property_value: skos:narrowMatch MetaCyc:RXN-8316
+property_value: skos:narrowMatch MetaCyc:RXN-8363
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -446322,8 +462126,23 @@
synonym: "1-18:1-2-18:2-phosphatidylcholine desaturase activity (SN2-18:3 forming)" EXACT []
xref: EC:1.14.19.25
xref: MetaCyc:RXN-16046
+xref: MetaCyc:RXN-8321
+xref: MetaCyc:RXN-8323
+xref: MetaCyc:RXN-8326
+xref: MetaCyc:RXN-8329
+xref: MetaCyc:RXN-8331
+xref: MetaCyc:RXN-8361
xref: RHEA:46404
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.25
+property_value: skos:exactMatch MetaCyc:RXN-16046
+property_value: skos:exactMatch RHEA:46404
+property_value: skos:narrowMatch MetaCyc:RXN-8321
+property_value: skos:narrowMatch MetaCyc:RXN-8323
+property_value: skos:narrowMatch MetaCyc:RXN-8326
+property_value: skos:narrowMatch MetaCyc:RXN-8329
+property_value: skos:narrowMatch MetaCyc:RXN-8331
+property_value: skos:narrowMatch MetaCyc:RXN-8361
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -446365,6 +462184,9 @@
xref: MetaCyc:RXN-8343
xref: RHEA:46536
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.38
+property_value: skos:exactMatch RHEA:46536
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102866
@@ -446375,7 +462197,16 @@
synonym: "Delta(5)-fatty-acid desaturase activity" EXACT []
synonym: "di-homo-gamma-linolenate delta5 desaturase activity" RELATED []
xref: EC:1.14.19.30
+xref: MetaCyc:RXN-8346
+xref: MetaCyc:RXN-8350
+xref: RHEA:46260
+xref: RHEA:46264
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.30
+property_value: skos:narrowMatch MetaCyc:RXN-8346
+property_value: skos:narrowMatch MetaCyc:RXN-8350
+property_value: skos:narrowMatch RHEA:46260
+property_value: skos:narrowMatch RHEA:46264
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -446464,6 +462295,9 @@
xref: MetaCyc:RXN-8386
xref: RHEA:19281
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.141
+property_value: skos:exactMatch RHEA:19281
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102877
@@ -446474,6 +462308,9 @@
xref: MetaCyc:RXN-8416
xref: RHEA:33991
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.133
+property_value: skos:exactMatch RHEA:33991
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102878
@@ -446484,6 +462321,8 @@
xref: MetaCyc:RXN-8417
xref: RHEA:29499
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.69
+property_value: skos:exactMatch RHEA:29499
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28819#issuecomment-2328362565" xsd:anyURI
[Term]
@@ -446495,6 +462334,9 @@
xref: MetaCyc:RXN-8418
xref: RHEA:30375
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.79
+property_value: skos:exactMatch RHEA:30375
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102880
@@ -446513,6 +462355,7 @@
xref: MetaCyc:RXN-8421
xref: RHEA:73983
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch RHEA:73983
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28819" xsd:anyURI
[Term]
@@ -446523,6 +462366,8 @@
xref: MetaCyc:RXN-8423
xref: RHEA:68520
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch MetaCyc:RXN-8423
+property_value: skos:exactMatch RHEA:68520
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
[Term]
@@ -446534,6 +462379,8 @@
xref: MetaCyc:RXN-8424
xref: RHEA:30379
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.78
+property_value: skos:exactMatch RHEA:30379
[Term]
id: GO:0102884
@@ -446544,6 +462391,9 @@
xref: MetaCyc:RXN-8425
xref: RHEA:28643
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.65
+property_value: skos:exactMatch RHEA:28643
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102885
@@ -446554,6 +462404,9 @@
xref: MetaCyc:RXN-8426
xref: RHEA:32027
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.95
+property_value: skos:exactMatch RHEA:32027
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102886
@@ -446573,6 +462426,9 @@
xref: MetaCyc:RXN-8430
xref: RHEA:32699
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.123
+property_value: skos:exactMatch RHEA:32699
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102888
@@ -446599,8 +462455,18 @@
def: "Catalysis of the reaction: UDP-alpha-D-glucose + 2',4,4',6'-tetrahydroxychalcone = UDP + 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H+. Also converts 2',3,4,4',6'-pentahydroxychalcone + UDP-alpha-D-glucose into 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside." [EC:2.4.1.286]
synonym: "naringenin chalcone 4'-O-glucosyltransferase activity" NARROW []
xref: EC:2.4.1.286
+xref: MetaCyc:RXN-8453
+xref: MetaCyc:RXN-8455
+xref: RHEA:34291
+xref: RHEA:34295
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.286
+property_value: skos:narrowMatch MetaCyc:RXN-8453
+property_value: skos:narrowMatch MetaCyc:RXN-8455
+property_value: skos:narrowMatch RHEA:34291
+property_value: skos:narrowMatch RHEA:34295
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102891
@@ -446646,6 +462512,9 @@
xref: MetaCyc:RXN-8496
xref: RHEA:28174
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.121
+property_value: skos:exactMatch RHEA:28174
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102896
@@ -446719,6 +462588,9 @@
xref: MetaCyc:RXN-8547
xref: RHEA:32559
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.114
+property_value: skos:exactMatch RHEA:32559
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102904
@@ -446729,6 +462601,9 @@
xref: MetaCyc:RXN-8561
xref: RHEA:28302
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.60
+property_value: skos:exactMatch RHEA:28302
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102905
@@ -446739,6 +462614,9 @@
xref: MetaCyc:RXN-8608
xref: RHEA:29511
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.73
+property_value: skos:exactMatch RHEA:29511
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102906
@@ -446749,6 +462627,9 @@
xref: MetaCyc:RXN-8609
xref: RHEA:30383
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.86
+property_value: skos:exactMatch RHEA:30383
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102907
@@ -446802,11 +462683,16 @@
id: GO:0102913
name: 3-aminomethylindole N-methyltransferase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 3-(aminomethyl)indole + S-adenosyl-L-methionine = (1H-indol-3-yl)-N-methylmethanamine + H+ + S-adenosyl-L-homocysteine." [RHEA:52268]
-xref: MetaCyc:RXN-8686
-xref: RHEA:52268
+def: "Catalysis of the reaction: 3-(aminomethyl)indole + 2 S-adenosyl-L-methionine = gramine + 2 S-adenosyl-L-homocysteine + 2 H+." [RHEA:52264]
+xref: EC:2.1.1.340
+xref: MetaCyc:RXN-18224
+xref: RHEA:52264
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.340
+property_value: skos:exactMatch MetaCyc:RXN-18224
+property_value: skos:exactMatch RHEA:52264
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
[Term]
id: GO:0102914
@@ -446823,7 +462709,16 @@
namespace: molecular_function
def: "Catalysis of the reaction: H+ + (+)-pinoresinol + NADPH + O2 = (+)-piperitol + NADP + 2 H2O." [EC:1.14.19.74, PMID:16785429]
xref: EC:1.14.19.74
+xref: MetaCyc:RXN-8695
+xref: MetaCyc:RXN-8696
+xref: RHEA:56776
+xref: RHEA:56780
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.19.74
+property_value: skos:narrowMatch MetaCyc:RXN-8695
+property_value: skos:narrowMatch MetaCyc:RXN-8696
+property_value: skos:narrowMatch RHEA:56776
+property_value: skos:narrowMatch RHEA:56780
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -446844,7 +462739,16 @@
synonym: "(R)-reticuline 7-O-methyltransferase activity" EXACT []
synonym: "(S)-reticuline 7-O-methyltransferase activity" EXACT []
xref: EC:2.1.1.291
+xref: MetaCyc:RXN-8700
+xref: MetaCyc:RXN-8701
+xref: RHEA:10444
+xref: RHEA:38907
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.291
+property_value: skos:narrowMatch MetaCyc:RXN-8700
+property_value: skos:narrowMatch MetaCyc:RXN-8701
+property_value: skos:narrowMatch RHEA:10444
+property_value: skos:narrowMatch RHEA:38907
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
@@ -446867,6 +462771,9 @@
xref: MetaCyc:RXN-8771
xref: RHEA:27345
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.79
+property_value: skos:exactMatch RHEA:27345
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102920
@@ -446887,6 +462794,9 @@
xref: MetaCyc:RXN-8849
xref: RHEA:30639
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.269
+property_value: skos:exactMatch RHEA:30639
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102922
@@ -446896,6 +462806,8 @@
xref: MetaCyc:RXN-8857
xref: RHEA:42488
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch MetaCyc:RXN-8857
+property_value: skos:exactMatch RHEA:42488
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -446906,6 +462818,8 @@
xref: MetaCyc:RXN-8859
xref: RHEA:33687
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch MetaCyc:RXN-8859
+property_value: skos:exactMatch RHEA:33687
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -446974,6 +462888,9 @@
xref: MetaCyc:RXN-8920
xref: RHEA:27854
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.93
+property_value: skos:exactMatch RHEA:27854
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102931
@@ -447001,6 +462918,9 @@
xref: MetaCyc:RXN-8953
xref: RHEA:36779
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch EC:2.6.1.102
+property_value: skos:exactMatch RHEA:36779
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102934
@@ -447011,6 +462931,9 @@
xref: MetaCyc:RXN-8971
xref: RHEA:28230
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.150
+property_value: skos:exactMatch RHEA:28230
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102935
@@ -447092,6 +463015,9 @@
xref: MetaCyc:RXN-9031
xref: RHEA:28182
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch EC:5.3.3.17
+property_value: skos:exactMatch RHEA:28182
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102944
@@ -447215,8 +463141,14 @@
xref: EC:1.1.1.295
xref: MetaCyc:RXN-9290
xref: RHEA:25363
+xref: RHEA:25367
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.295
+property_value: skos:exactMatch RHEA:25363
+property_value: skos:narrowMatch RHEA:25363
+property_value: skos:narrowMatch RHEA:25367
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19648" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102963
@@ -447227,7 +463159,10 @@
xref: MetaCyc:RXN-9314
xref: RHEA:51540
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.51
+property_value: skos:exactMatch RHEA:51540
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21133" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102964
@@ -447237,6 +463172,9 @@
xref: MetaCyc:RXN-9315
xref: RHEA:51524
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.337
+property_value: skos:exactMatch MetaCyc:RXN-9315
+property_value: skos:exactMatch RHEA:51524
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -447250,8 +463188,11 @@
xref: MetaCyc:RXN-9344
xref: RHEA:52716
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.84
+property_value: skos:exactMatch RHEA:52716
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24250" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102966
@@ -447271,6 +463212,8 @@
xref: MetaCyc:RXN-9367
xref: RHEA:32607
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:32607
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102968
@@ -447280,6 +463223,8 @@
xref: MetaCyc:RXN-9369
xref: RHEA:32611
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:32611
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102969
@@ -447289,6 +463234,8 @@
xref: MetaCyc:RXN-9370
xref: RHEA:32615
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:32615
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102970
@@ -447299,6 +463246,9 @@
xref: MetaCyc:RXN-9372
xref: RHEA:39895
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.323
+property_value: skos:exactMatch RHEA:39895
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102971
@@ -447309,6 +463259,9 @@
xref: MetaCyc:RXN-9382
xref: RHEA:12597
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.183
+property_value: skos:exactMatch RHEA:12597
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102972
@@ -447331,6 +463284,9 @@
xref: MetaCyc:RXN-9479
xref: RHEA:35179
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.221
+property_value: skos:exactMatch RHEA:35179
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102974
@@ -447340,6 +463296,8 @@
xref: MetaCyc:RXN-9489
xref: RHEA:35691
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.1.1.353
+property_value: skos:exactMatch RHEA:35691
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -447350,6 +463308,8 @@
xref: MetaCyc:RXN-9490
xref: RHEA:35695
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.1.1.353
+property_value: skos:exactMatch RHEA:35695
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -447360,6 +463320,8 @@
xref: MetaCyc:RXN-9491
xref: RHEA:35699
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.1.1.353
+property_value: skos:exactMatch RHEA:35699
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -447379,8 +463341,17 @@
def: "Catalysis of the reaction: 4-hydroxy-2,5-dimethylfuran-3-one + NADP = 4-hydroxy-5-methyl-2-methylenefuran-3-one + NADPH + H+." [EC:1.3.1.105, GOC:pz]
xref: EC:1.3.1.105
xref: MetaCyc:RXN-9563
+xref: MetaCyc:RXN-9564
+xref: MetaCyc:RXN-9565
+xref: MetaCyc:RXN-9567
xref: RHEA:39111
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.105
+property_value: skos:exactMatch MetaCyc:RXN-9563
+property_value: skos:exactMatch RHEA:39111
+property_value: skos:narrowMatch MetaCyc:RXN-9564
+property_value: skos:narrowMatch MetaCyc:RXN-9565
+property_value: skos:narrowMatch MetaCyc:RXN-9567
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
[Term]
@@ -447421,7 +463392,9 @@
xref: MetaCyc:RXN-9578
xref: RHEA:35755
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:35755
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25302" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102983
@@ -447431,6 +463404,8 @@
xref: EC:2.4.2.41
xref: MetaCyc:RXN-9589
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.41
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102984
@@ -447441,6 +463416,9 @@
xref: MetaCyc:RXN-9592
xref: RHEA:25637
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.73
+property_value: skos:exactMatch RHEA:25637
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102985
@@ -447449,7 +463427,16 @@
def: "Catalysis of the introduction of a cis double bond at position 12 of fatty-acyl-CoAs that contain a cis double bond at position 9. Specific reactions include: (9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O; and (9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O." [EC:1.14.19.6]
synonym: "delta12-fatty-acid desaturase activity" EXACT []
xref: EC:1.14.19.6
+xref: MetaCyc:RXN-9601
+xref: MetaCyc:RXN-9616
+xref: RHEA:25856
+xref: RHEA:45096
is_a: GO:0016215 ! acyl-CoA desaturase activity
+property_value: skos:exactMatch EC:1.14.19.6
+property_value: skos:narrowMatch MetaCyc:RXN-9601
+property_value: skos:narrowMatch MetaCyc:RXN-9616
+property_value: skos:narrowMatch RHEA:25856
+property_value: skos:narrowMatch RHEA:45096
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29820" xsd:anyURI
@@ -447463,6 +463450,12 @@
xref: MetaCyc:RXN-9603
xref: RHEA:47416
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.245
+property_value: skos:exactMatch MetaCyc:RXN-9603
+property_value: skos:exactMatch RHEA:47416
+property_value: skos:relatedMatch MetaCyc:PWY-2622
+property_value: skos:relatedMatch MetaCyc:PWY-5983
+property_value: skos:relatedMatch MetaCyc:PWY-5985
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI
[Term]
@@ -447485,8 +463478,11 @@
xref: MetaCyc:RXN-9617
xref: RHEA:46232
is_a: GO:0016215 ! acyl-CoA desaturase activity
+property_value: skos:exactMatch EC:1.14.19.13
+property_value: skos:exactMatch RHEA:46232
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29820" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102989
@@ -447506,6 +463502,9 @@
xref: MetaCyc:RXN-9619
xref: RHEA:26325
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.n7
+property_value: skos:exactMatch MetaCyc:RXN-9619
+property_value: skos:exactMatch RHEA:26325
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -447536,8 +463535,36 @@
comment: Introduces a cis double bond at a location 3 carbons away from the methyl end of the fatty acid. Acts on all 16:2- or 18:2-containing chloroplast membrane lipids, including phosphatidylglycerol, monogalactosyldiacylglycerol, digalactosyldiaclyglycerol, and sulfoquinovosyldiacylglycerol.
synonym: "linolenate delta15 desaturase activity" EXACT []
xref: EC:1.14.19.35
+xref: MetaCyc:RXN-1727
+xref: MetaCyc:RXN-8295
+xref: MetaCyc:RXN-8297
+xref: MetaCyc:RXN-8299
+xref: MetaCyc:RXN-8301
+xref: MetaCyc:RXN-8303
+xref: MetaCyc:RXN-8309
+xref: MetaCyc:RXN-8310
+xref: MetaCyc:RXN-8314
+xref: MetaCyc:RXN-8365
+xref: MetaCyc:RXN-8366
xref: MetaCyc:RXN-9667
+xref: RHEA:46408
+xref: RHEA:46412
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.35
+property_value: skos:exactMatch MetaCyc:RXN-9667
+property_value: skos:narrowMatch MetaCyc:RXN-1727
+property_value: skos:narrowMatch MetaCyc:RXN-8295
+property_value: skos:narrowMatch MetaCyc:RXN-8297
+property_value: skos:narrowMatch MetaCyc:RXN-8299
+property_value: skos:narrowMatch MetaCyc:RXN-8301
+property_value: skos:narrowMatch MetaCyc:RXN-8303
+property_value: skos:narrowMatch MetaCyc:RXN-8309
+property_value: skos:narrowMatch MetaCyc:RXN-8310
+property_value: skos:narrowMatch MetaCyc:RXN-8314
+property_value: skos:narrowMatch MetaCyc:RXN-8365
+property_value: skos:narrowMatch MetaCyc:RXN-8366
+property_value: skos:narrowMatch RHEA:46408
+property_value: skos:narrowMatch RHEA:46412
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -447549,6 +463576,9 @@
xref: MetaCyc:RXN-9689
xref: RHEA:27481
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.148
+property_value: skos:exactMatch RHEA:27481
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102996
@@ -447580,7 +463610,10 @@
xref: RHEA:33711
xref: UM-BBD_reactionID:r0583
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.92
+property_value: skos:exactMatch RHEA:33711
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0102999
@@ -447607,8 +463640,18 @@
def: "Catalysis of the reactions: dimethyl sulfoxide + H+ + NADH + O2 = dimethyl sulfone + H2O + NAD+ and dimethyl sulfide + H+ + NADH + O2 = dimethyl sulfoxide + H2O + NAD+." [EC:1.14.13.245, PMID:9345770]
synonym: "assimilatory dimethylsulfide S-monooxygenase activity" EXACT []
xref: EC:1.14.13.245
+xref: MetaCyc:RXN-20073
+xref: MetaCyc:RXN-9767
+xref: RHEA:57956
+xref: RHEA:57960
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.245
+property_value: skos:narrowMatch MetaCyc:RXN-20073
+property_value: skos:narrowMatch MetaCyc:RXN-9767
+property_value: skos:narrowMatch RHEA:57956
+property_value: skos:narrowMatch RHEA:57960
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27862" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103002
@@ -447661,6 +463704,9 @@
xref: MetaCyc:RXN-9825
xref: RHEA:36131
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.278
+property_value: skos:exactMatch RHEA:36131
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103008
@@ -447700,6 +463746,9 @@
xref: MetaCyc:RXN-9935
xref: RHEA:26039
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.246
+property_value: skos:exactMatch RHEA:26039
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103012
@@ -447712,7 +463761,10 @@
xref: MetaCyc:RXN-9944
xref: RHEA:42336
is_a: GO:0016673 ! oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.8.7.2
+property_value: skos:exactMatch RHEA:42336
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18939" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103014
@@ -447732,6 +463784,9 @@
xref: MetaCyc:RXN0-2001
xref: RHEA:35371
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.43
+property_value: skos:exactMatch RHEA:35371
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103016
@@ -447745,7 +463800,10 @@
xref: RHEA:47032
is_a: GO:0016783 ! sulfurtransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.8.1.13
+property_value: skos:exactMatch RHEA:47032
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27928" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103020
@@ -447755,6 +463813,8 @@
xref: MetaCyc:RXN0-382
xref: RHEA:27990
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch RHEA:27990
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103023
@@ -447765,7 +463825,10 @@
xref: MetaCyc:RXN0-5073
xref: RHEA:28330
is_a: GO:0017111 ! ribonucleoside triphosphate phosphatase activity
+property_value: skos:exactMatch EC:3.6.1.73
+property_value: skos:exactMatch RHEA:28330
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103026
@@ -447775,6 +463838,8 @@
xref: MetaCyc:RXN0-5186
xref: RHEA:35603
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch MetaCyc:RXN0-5186
+property_value: skos:exactMatch RHEA:35603
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
[Term]
@@ -447815,6 +463880,10 @@
xref: MetaCyc:RXN0-5228
xref: RHEA:28394
is_a: GO:0016855 ! racemase and epimerase activity, acting on amino acids and derivatives
+property_value: skos:exactMatch EC:5.1.1.20
+property_value: skos:exactMatch MetaCyc:RXN0-5228
+property_value: skos:exactMatch RHEA:28394
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103032
@@ -447851,6 +463920,8 @@
synonym: "NADH:menaquinone oxidoreductase activity" EXACT []
xref: RHEA:29235
is_a: GO:0050136 ! NADH dehydrogenase (quinone) (non-electrogenic) activity
+property_value: skos:exactMatch RHEA:29235
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30272" xsd:anyURI
[Term]
@@ -447872,6 +463943,9 @@
xref: RHEA:37087
is_a: GO:0035596 ! methylthiotransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:2.8.4.4
+property_value: skos:exactMatch RHEA:37087
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103040
@@ -447890,6 +463964,7 @@
xref: MetaCyc:RXN0-6385
xref: RHEA:83859
is_a: GO:0016783 ! sulfurtransferase activity
+property_value: skos:exactMatch RHEA:83859
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28942" xsd:anyURI
[Term]
@@ -447900,6 +463975,8 @@
xref: MetaCyc:RXN0-6563
xref: RHEA:28779
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch RHEA:28779
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103043
@@ -447911,6 +463988,9 @@
xref: MetaCyc:RXN0-6710
xref: RHEA:34795
is_a: GO:0008081 ! phosphoric diester hydrolase activity
+property_value: skos:exactMatch EC:3.1.4.55
+property_value: skos:exactMatch RHEA:34795
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103044
@@ -447929,7 +464009,9 @@
xref: MetaCyc:RXN0-6948
xref: RHEA:44144
is_a: GO:0140085 ! L-amino-acid N-acetyltransferase activity
+property_value: skos:exactMatch RHEA:44144
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28554" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103046
@@ -448077,6 +464159,9 @@
xref: MetaCyc:RXN3O-663
xref: RHEA:64596
is_a: GO:0000030 ! mannosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.370
+property_value: skos:exactMatch MetaCyc:RXN3O-663
+property_value: skos:exactMatch RHEA:64596
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21803" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23995" xsd:anyURI
@@ -448108,6 +464193,8 @@
xref: EC:2.3.2.2
xref: MetaCyc:RXN66-336
is_a: GO:0016755 ! aminoacyltransferase activity
+property_value: skos:exactMatch EC:2.3.2.2
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103069
@@ -448117,6 +464204,8 @@
xref: MetaCyc:RXN66-356
xref: RHEA:50308
is_a: GO:0004509 ! steroid 21-monooxygenase activity
+property_value: skos:exactMatch RHEA:50308
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103071
@@ -448147,6 +464236,9 @@
xref: MetaCyc:RXN8J2-136
xref: RHEA:37547
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.361
+property_value: skos:exactMatch RHEA:37547
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103075
@@ -448157,6 +464249,9 @@
xref: MetaCyc:RXNDQC-2
xref: RHEA:34331
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.168
+property_value: skos:exactMatch RHEA:34331
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103077
@@ -448453,8 +464548,11 @@
xref: EC:2.7.1.193
xref: RHEA:49240
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.193
+property_value: skos:exactMatch RHEA:49240
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27410" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27694" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103113
@@ -448478,7 +464576,10 @@
is_a: GO:0005354 ! galactose transmembrane transporter activity
is_a: GO:0015407 ! ABC-type monosaccharide transporter activity
relationship: part_of GO:0042875 ! D-galactonate transmembrane transport
+property_value: skos:exactMatch EC:7.5.2.9
+property_value: skos:exactMatch RHEA:61716
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0103117
@@ -448489,6 +464590,8 @@
xref: MetaCyc:UDPACYLGLCNACDEACETYL-RXN
xref: RHEA:67816
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.108
+property_value: skos:exactMatch RHEA:67816
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
[Term]
@@ -448503,7 +464606,10 @@
xref: MetaCyc:RXN-22482
xref: RHEA:53836
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.191
+property_value: skos:exactMatch RHEA:53836
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30153" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
[Term]
id: GO:0104004
@@ -448641,10 +464747,12 @@
id: GO:0106008
name: 2-oxoglutaramate amidase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 2-oxoglutaramate + H2O = 2-oxoglutarate + NH3." [EC:3.5.1.111, PMID:21288482]
+def: "Catalysis of the reaction: 2-oxoglutaramate + H2O = 2-oxoglutarate + NH3." [PMID:21288482, RHEA:32963]
xref: EC:3.5.1.111
xref: RHEA:32963
-is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+is_a: GO:0050152 ! omega-amidase activity
+property_value: skos:exactMatch EC:3.5.1.111
+property_value: skos:exactMatch RHEA:32963
created_by: hjd
creation_date: 2017-04-25T14:10:02Z
@@ -448656,6 +464764,8 @@
xref: EC:4.1.3.42
xref: RHEA:35639
is_a: GO:0016833 ! oxo-acid-lyase activity
+property_value: skos:exactMatch EC:4.1.3.42
+property_value: skos:exactMatch RHEA:35639
created_by: hjd
creation_date: 2017-04-25T14:14:58Z
@@ -448853,6 +464963,8 @@
def: "Catalysis of the reaction: glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H+." [PMID:28362257, RHEA:53744]
xref: RHEA:53744
is_a: GO:0002161 ! aminoacyl-tRNA deacylase activity
+property_value: skos:broadMatch EC:3.1.1.96
+property_value: skos:exactMatch RHEA:53744
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29746" xsd:anyURI
created_by: hjd
creation_date: 2017-06-16T17:13:33Z
@@ -448889,7 +465001,9 @@
xref: RHEA:54572
is_a: GO:0009982 ! pseudouridine synthase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch RHEA:54572
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26797" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2017-06-26T17:37:30Z
@@ -448910,7 +465024,9 @@
xref: RHEA:51124
is_a: GO:0009982 ! pseudouridine synthase activity
is_a: GO:0140098 ! catalytic activity, acting on RNA
+property_value: skos:exactMatch RHEA:51124
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26618" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2017-06-28T17:44:20Z
@@ -449178,8 +465294,11 @@
xref: MetaCyc:RXN-11869
xref: RHEA:42968
is_a: GO:0016427 ! tRNA (cytidine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.206
+property_value: skos:exactMatch RHEA:42968
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24771" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26018" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2017-10-05T19:02:22Z
@@ -449317,7 +465436,10 @@
xref: MetaCyc:RXN-5472
xref: RHEA:29543
is_a: GO:0004583 ! dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.256
+property_value: skos:exactMatch RHEA:29543
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28029" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2017-11-28T19:16:37Z
@@ -449477,11 +465599,12 @@
[Term]
id: GO:0106092
-name: glial cell projection elongation involved in axon ensheathment
+name: obsolete glial cell projection elongation involved in axon ensheathment
namespace: biological_process
-def: "The extension of a glial cell process or projection to wrap around an axon." [GOC:ha, PMID:27131624]
-is_a: GO:0008366 ! axon ensheathment
-is_a: GO:0106091 ! glial cell projection elongation
+def: "OBSOLETE. The extension of a glial cell process or projection to wrap around an axon." [GOC:ha, PMID:27131624]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: hjd
creation_date: 2018-01-26T19:43:00Z
@@ -449560,6 +465683,9 @@
xref: EC:4.1.2.53
xref: RHEA:25784
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.53
+property_value: skos:exactMatch RHEA:25784
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2018-02-15T16:12:17Z
@@ -449567,8 +465693,15 @@
id: GO:0106100
name: beta-pinacene synthase activity
namespace: molecular_function
-def: "Catalysis of the cyclization of geranylgeranyl pyrophosphate (GGPP) to yield the monocyclic diterpene beta-pinacene." [GOC:rjd, PMID:28696553]
+def: "Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate = beta-pinacene + diphosphate." [PMID:28696553, RHEA:58172]
+xref: EC:4.2.3.200
+xref: MetaCyc:RXN-20045
+xref: RHEA:58172
is_a: GO:0010333 ! terpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.200
+property_value: skos:exactMatch MetaCyc:RXN-20045
+property_value: skos:exactMatch RHEA:58172
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: hjd
creation_date: 2018-02-15T16:51:59Z
@@ -449614,6 +465747,7 @@
synonym: "L-alanyl-tRNA(Thr) deacylase" EXACT []
xref: RHEA:17793
is_a: GO:0002161 ! aminoacyl-tRNA deacylase activity
+property_value: skos:exactMatch RHEA:17793
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29746" xsd:anyURI
created_by: hjd
creation_date: 2018-03-14T22:03:29Z
@@ -449624,7 +465758,6 @@
namespace: biological_process
def: "The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature." [PMID:27876809]
synonym: "CIT" RELATED []
-is_a: GO:0001659 ! temperature homeostasis
is_a: GO:1990845 ! adaptive thermogenesis
created_by: hjd
creation_date: 2018-03-21T20:30:52Z
@@ -449998,7 +466131,10 @@
xref: EC:2.5.1.129
xref: RHEA:37743
is_a: GO:0004659 ! prenyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.129
+property_value: skos:exactMatch RHEA:37743
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2018-08-17T18:50:00Z
@@ -450013,6 +466149,9 @@
xref: EC:2.1.1.287
xref: RHEA:43792
is_a: GO:0016433 ! rRNA (adenine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.287
+property_value: skos:exactMatch RHEA:43792
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2018-08-22T20:13:21Z
@@ -450037,6 +466176,9 @@
xref: EC:1.14.14.164
xref: RHEA:57844
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.164
+property_value: skos:exactMatch RHEA:57844
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2018-09-07T18:24:41Z
@@ -450048,6 +466190,9 @@
xref: EC:1.14.11.60
xref: RHEA:57848
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.11.60
+property_value: skos:exactMatch RHEA:57848
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2018-09-07T18:28:16Z
@@ -450086,6 +466231,9 @@
xref: EC:1.14.14.165
xref: RHEA:57864
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.165
+property_value: skos:exactMatch RHEA:57864
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2018-09-10T19:44:15Z
@@ -450142,6 +466290,9 @@
xref: RHEA:57152
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:1.14.11.63
+property_value: skos:exactMatch RHEA:57152
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2018-11-15T20:09:45Z
@@ -450154,6 +466305,8 @@
xref: RHEA:57156
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch RHEA:57156
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2018-11-26T14:59:18Z
@@ -450170,7 +466323,10 @@
xref: RHEA:56744
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch EC:1.14.11.73
+property_value: skos:exactMatch RHEA:56744
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16689" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2018-11-26T15:05:57Z
@@ -450183,7 +466339,9 @@
synonym: "GPACT activity" EXACT []
xref: RHEA:58476
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch RHEA:58476
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16665" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2018-11-26T21:21:03Z
@@ -450227,6 +466385,8 @@
def: "Catalysis of the reaction: a cytidine in mRNA + acetyl-CoA + ATP + H2O = ADP + an N(4)-acetylcytidine in mRNA + CoA + H+ + phosphate." [GOC:sp, PMID:30449621, RHEA:58480]
xref: RHEA:58480
is_a: GO:0008080 ! N-acetyltransferase activity
+property_value: skos:exactMatch RHEA:58480
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2018-12-18T19:19:06Z
@@ -450348,6 +466508,8 @@
def: "Catalysis of the reaction: cyclic GMP-AMP + 2 H2O = AMP + GMP." [GOC:sp, PMID:25344812, RHEA:58808]
xref: RHEA:58808
is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
+property_value: skos:exactMatch RHEA:58808
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-03-07T21:06:24Z
@@ -450633,6 +466795,8 @@
synonym: "5-PP-InsP4 activity" EXACT []
xref: RHEA:59500
is_a: GO:0052840 ! inositol diphosphate tetrakisphosphate diphosphatase activity
+property_value: skos:exactMatch RHEA:59500
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-06-06T19:26:38Z
@@ -450761,7 +466925,10 @@
xref: MetaCyc:RXN-19749
xref: RHEA:30303
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.95
+property_value: skos:exactMatch RHEA:30303
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21412" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-09-06T16:36:25Z
@@ -450783,6 +466950,8 @@
def: "Catalysis of the reaction: 2-hydroxyisobutyryl-CoA + lysine in peptide = CoA + N-2-hydroxyisobutyryl-lysine-peptide." [GOC:sp, PMID:29775581]
xref: RHEA:24180
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch RHEA:24180
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-10-17T18:55:24Z
@@ -450801,9 +466970,10 @@
name: peptide glutaryltransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: glutaryl-CoA + L-lysyl-[protein] = CoA + H+ + N6-glutaryl-L-lysyl-[protein]." [GOC:sp, PMID:31542297]
-xref: Reactome:R-HSA-9858590 "DLST transfers glutaryl to CoA"
xref: RHEA:18009
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch RHEA:18009
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-10-17T18:58:56Z
@@ -450814,6 +466984,7 @@
def: "Catalysis of the reaction: glutaryl-CoA + histone = CoA + H+ + N6-glutaryl-histone." [GOC:sp, PMID:31542297]
is_a: GO:0106228 ! peptide glutaryltransferase activity
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:broadMatch RHEA:18009
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: hjd
creation_date: 2019-10-17T19:01:48Z
@@ -450836,7 +467007,9 @@
comment: This reaction is the removal of a propionyl group from a propionylated lysine residue of a protein or peptide.
xref: RHEA:23500
is_a: GO:0141218 ! NAD-dependent protein lysine deacylase activity
+property_value: skos:exactMatch RHEA:23500
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28920" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-10-18T14:14:47Z
@@ -450881,6 +467054,8 @@
def: "Catalysis of the reaction: ceramide-1-phosphate + H2O = ceramide+ phosphate." [GOC:lb, PMID:10359651]
xref: RHEA:50888
is_a: GO:0042577 ! lipid phosphatase activity
+property_value: skos:exactMatch RHEA:50888
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-11-21T20:40:39Z
@@ -450901,6 +467076,8 @@
def: "Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,10E,12R,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate." [GOC:gap, PMID:10100631, PMID:11256953, RHEA:41336]
xref: RHEA:41336
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch RHEA:41336
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-12-18T21:03:02Z
@@ -450912,6 +467089,9 @@
xref: EC:4.2.1.174
xref: RHEA:54652
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.174
+property_value: skos:exactMatch RHEA:54652
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-12-19T15:28:28Z
@@ -450923,6 +467103,9 @@
xref: EC:4.2.3.189
xref: RHEA:54512
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch EC:4.2.3.189
+property_value: skos:exactMatch RHEA:54512
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-12-19T16:00:49Z
@@ -450933,6 +467116,8 @@
def: "Catalysis of the reaction: O2 + peregrinol + reduced [NADPH--hemoprotein reductase] = H+ + H2O + labd-13Z-ene-9,15,16-triol + oxidized [NADPH--hemoprotein reductase]." [GOC:eab, PMID:29315936, RHEA:62192]
xref: RHEA:62192
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:62192
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-12-19T17:43:00Z
@@ -450944,6 +467129,9 @@
xref: EC:5.5.1.29
xref: RHEA:54676
is_a: GO:0016872 ! intramolecular lyase activity
+property_value: skos:exactMatch EC:5.5.1.29
+property_value: skos:exactMatch RHEA:54676
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-12-19T18:31:00Z
@@ -450954,6 +467142,8 @@
def: "Catalysis of the reaction: 9alpha-copalyl diphosphate = diphosphate + syn-isopimara-7,15-diene." [GOC:emb, PMID:29315936, RHEA:62188]
xref: RHEA:62188
is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates
+property_value: skos:exactMatch RHEA:62188
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-12-19T19:04:32Z
@@ -450965,6 +467155,9 @@
xref: EC:1.14.14.169
xref: RHEA:57972
is_a: GO:0004497 ! monooxygenase activity
+property_value: skos:exactMatch EC:1.14.14.169
+property_value: skos:exactMatch RHEA:57972
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2019-12-20T14:50:15Z
@@ -450976,6 +467169,9 @@
xref: EC:2.7.8.29
xref: RHEA:27606
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch EC:2.7.8.29
+property_value: skos:exactMatch RHEA:27606
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-01-22T15:27:57Z
@@ -451046,19 +467242,19 @@
def: "Catalysis of the reaction N4-acetylcytidine +H2O = cytidine + acetate." [GOC:imk, PMID:31964920, RHEA:62932]
xref: RHEA:62932
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch RHEA:62932
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-02-19T20:31:17Z
[Term]
id: GO:0106253
-name: positive regulation of DNA strand resection involved in replication fork processing
+name: obsolete positive regulation of DNA strand resection involved in replication fork processing
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of DNA strand resection involved in replication fork processing." [GOC:vw, PMID:31575705]
-is_a: GO:0051054 ! positive regulation of DNA metabolic process
-is_a: GO:0110026 ! regulation of DNA strand resection involved in replication fork processing
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0110025 ! DNA strand resection involved in replication fork processing
-relationship: positively_regulates GO:0110025 ! DNA strand resection involved in replication fork processing
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of DNA strand resection involved in replication fork processing." [GOC:vw, PMID:31575705]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: hjd
creation_date: 2020-02-24T15:31:30Z
@@ -451078,10 +467274,11 @@
namespace: molecular_function
def: "A hydroperoxy icosatetraenoate = a hydroxy epoxy icosatrienoate." [PMID:12881489, RHEA:55560]
xref: EC:5.4.4.7
-xref: Reactome:R-HSA-2161794 "Arachidonate is converted to HXA3/B3 by ALOX12"
-xref: Reactome:R-HSA-8942208 "ALOXE3 isomerises 12R-HpETE to HXA3"
xref: RHEA:55560
is_a: GO:0050486 ! intramolecular hydroxytransferase activity
+property_value: skos:exactMatch EC:5.4.4.7
+property_value: skos:exactMatch RHEA:55560
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-03-20T14:00:30Z
@@ -451093,6 +467290,9 @@
xref: EC:4.2.1.152
xref: RHEA:55556
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.152
+property_value: skos:exactMatch RHEA:55556
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-03-20T14:40:16Z
@@ -451103,6 +467303,8 @@
def: "Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline." [PMID:19014349, RHEA:45088]
xref: RHEA:45088
is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups
+property_value: skos:exactMatch RHEA:45088
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-04-21T17:31:56Z
@@ -451142,8 +467344,11 @@
xref: RHEA:61020
is_a: GO:0016407 ! acetyltransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.3.1.311
+property_value: skos:exactMatch RHEA:61020
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24847#event-8410069181" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30124" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-05-08T15:21:51Z
@@ -451155,7 +467360,10 @@
xref: EC:2.3.1.n7
xref: RHEA:32995
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.n7
+property_value: skos:exactMatch RHEA:32995
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27226" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-05-18T15:09:57Z
@@ -451167,7 +467375,10 @@
xref: EC:2.3.1.n6
xref: RHEA:33191
is_a: GO:0008374 ! O-acyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.n6
+property_value: skos:exactMatch RHEA:33191
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27226" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-05-18T15:12:42Z
@@ -451178,6 +467389,7 @@
def: "Catalysis of the reactions: GTP + L-seryl-[protein] = GDP + H+ + O-phospho-L-seryl-[protein]." [GOC:sp, PMID:32322062, RHEA:64020]
xref: RHEA:64020
is_a: GO:0004672 ! protein kinase activity
+property_value: skos:exactMatch RHEA:64020
created_by: hjd
creation_date: 2020-05-28T18:51:18Z
@@ -451189,6 +467401,8 @@
synonym: "polyketide syntase" BROAD []
xref: RHEA:64352
is_a: GO:0016740 ! transferase activity
+property_value: skos:exactMatch RHEA:64352
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-06-02T18:05:33Z
@@ -451199,6 +467413,8 @@
def: "Catalysis of the reaction: 2,4,6-trihydroxyphenylhexan-1-one + chloride + FADH2 + O2 = (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + H+ + 2 H2O." [PMID:20231486, RHEA:64356]
xref: RHEA:64356
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:64356
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-06-02T18:13:44Z
@@ -451209,6 +467425,8 @@
def: "Catalysis of the reaction: (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2 = (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O." [PMID:20231486, RHEA:64360]
xref: RHEA:64360
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:64360
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-06-02T18:16:23Z
@@ -451220,6 +467438,8 @@
synonym: "DIF-1 syntase" RELATED []
xref: RHEA:48396
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch RHEA:48396
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-06-02T18:25:03Z
@@ -451230,6 +467450,7 @@
def: "Catalysis of the reaction: D-arabinose + NADP+ = D-arabinono-1,4-lactone + NADPH." [RHEA:21892]
xref: RHEA:21892
is_a: GO:0045290 ! D-arabinose 1-dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch RHEA:21892
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
created_by: hjd
creation_date: 2020-06-23T18:47:25Z
@@ -451274,7 +467495,10 @@
xref: Reactome:R-HSA-1972385 "ADP-Ribosylation of HNP-1"
xref: RHEA:19149
is_a: GO:1990404 ! NAD+-protein mono-ADP-ribosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.31
+property_value: skos:exactMatch RHEA:19149
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22874" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-07-02T01:37:02Z
@@ -451286,8 +467510,10 @@
synonym: "biliberdin reductase (NAD+) activity" EXACT []
xref: RHEA:15797
is_a: GO:0004074 ! biliverdin reductase [NAD(P)H] activity
+property_value: skos:exactMatch RHEA:15797
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-07-02T01:48:07Z
@@ -451299,8 +467525,10 @@
synonym: "biliverdin reductase (NADP+) activity" EXACT []
xref: RHEA:15793
is_a: GO:0004074 ! biliverdin reductase [NAD(P)H] activity
+property_value: skos:exactMatch RHEA:15793
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-07-02T01:50:24Z
@@ -451373,6 +467601,8 @@
def: "Catalysis of the reaction: chenodeoxycholate + NAD+ = 7-oxolithocholate + H+ + NADH." [PMID:12917011, RHEA:42036]
xref: RHEA:42036
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:42036
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-07-29T17:48:25Z
@@ -451383,6 +467613,8 @@
def: "Catalysis of the reaction: 3-beta,7-beta-dihydroxy-5-beta-cholan-24-oate + NAD+ = 3-beta-hydroxy-7-oxo-5-beta-cholan-24-oate + H+ + NADH." [PMID:12917011, RHEA:42024]
xref: RHEA:42024
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:42024
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-07-29T17:51:00Z
@@ -451393,6 +467625,8 @@
def: "Catalysis of the reaction: NAD+ + ursodeoxycholate = 7-oxolithocholate + H+ + NADH." [PMID:12917011, RHEA:42028]
xref: RHEA:42028
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:42028
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-07-29T17:52:44Z
@@ -451403,6 +467637,8 @@
def: "Catalysis of the reaction: (E)-caffeate + ATP + CoA = (E)-caffeoyl-CoA + AMP + diphosphate." [PMID:22649270, RHEA:36299]
xref: RHEA:36299
is_a: GO:0016405 ! CoA-ligase activity
+property_value: skos:exactMatch RHEA:36299
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-07-30T14:26:08Z
@@ -451438,6 +467674,8 @@
def: "Catalysis of the reaction: (E)-cinnamate + ATP + CoA = (E)-cinnamoyl-CoA + AMP + diphosphate." [PMID:22649270, RHEA:64788]
xref: RHEA:64788
is_a: GO:0016405 ! CoA-ligase activity
+property_value: skos:exactMatch RHEA:64788
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-08-18T16:53:10Z
@@ -451448,6 +467686,8 @@
def: "Catalysis of the reaction: NADH + 2 O2 = H+ + NAD+ + 2 superoxide." [RHEA:63184]
xref: RHEA:63184
is_a: GO:0016175 ! superoxide-generating NAD(P)H oxidase activity
+property_value: skos:exactMatch RHEA:63184
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-08-19T15:56:43Z
@@ -451458,6 +467698,8 @@
def: "Catalysis of the reaction: NADPH + 2 O2 = H+ + NADP+ + 2 superoxide." [RHEA:63180]
xref: RHEA:63180
is_a: GO:0016175 ! superoxide-generating NAD(P)H oxidase activity
+property_value: skos:exactMatch RHEA:63180
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-08-19T15:58:36Z
@@ -451551,7 +467793,9 @@
synonym: "arachidonic acid 5,6-epoxygenase activity" EXACT []
xref: RHEA:49936
is_a: GO:0008392 ! arachidonate epoxygenase activity
+property_value: skos:exactMatch RHEA:49936
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28648" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-08-28T19:08:45Z
@@ -451563,7 +467807,9 @@
synonym: "arachidonic acid 8,9-epoxygenase activity" EXACT []
xref: RHEA:64984
is_a: GO:0008392 ! arachidonate epoxygenase activity
+property_value: skos:exactMatch RHEA:64984
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28648" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-08-28T19:10:07Z
@@ -451617,6 +467863,8 @@
xref: Reactome:R-HSA-193981 "CYP21A2 oxidises 17HPROG"
xref: RHEA:50304
is_a: GO:0004509 ! steroid 21-monooxygenase activity
+property_value: skos:exactMatch RHEA:50304
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-09-21T14:40:30Z
@@ -451635,6 +467883,7 @@
xref: Reactome:R-HSA-9860808 "p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179"
xref: RHEA:17989
is_a: GO:0004672 ! protein kinase activity
+property_value: skos:exactMatch RHEA:17989
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20114" xsd:anyURI
created_by: hjd
creation_date: 2020-09-22T20:01:17Z
@@ -451648,7 +467897,10 @@
xref: MetaCyc:RXN-22438
xref: RHEA:19821
is_a: GO:0004489 ! methylenetetrahydrofolate reductase [NAD(P)H] activity
+property_value: skos:exactMatch EC:1.5.1.54
+property_value: skos:exactMatch RHEA:19821
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27535" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-09-23T14:20:07Z
@@ -451661,7 +467913,10 @@
xref: MetaCyc:RXN-21991
xref: RHEA:19817
is_a: GO:0004489 ! methylenetetrahydrofolate reductase [NAD(P)H] activity
+property_value: skos:exactMatch EC:1.5.1.53
+property_value: skos:exactMatch RHEA:19817
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27535" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-09-23T14:20:27Z
@@ -451672,6 +467927,7 @@
def: "Catalysis of the reaction: ammonium hydroxide + 3 NADP+ + H2O = nitrite + 3 NADPH + 3 H+." [RHEA:24632]
xref: RHEA:24632
is_a: GO:0008942 ! nitrite reductase [NAD(P)H] activity
+property_value: skos:exactMatch RHEA:24632
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26482" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28557" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30026" xsd:anyURI
@@ -451686,6 +467942,8 @@
xref: EC:1.7.1.15
xref: RHEA:24628
is_a: GO:0008942 ! nitrite reductase [NAD(P)H] activity
+property_value: skos:exactMatch EC:1.7.1.15
+property_value: skos:exactMatch RHEA:24628
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28557" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30026" xsd:anyURI
created_by: hjd
@@ -451746,7 +468004,9 @@
def: "Catalysis of the reaction: S-(hydroxymethyl)glutathione + NADP+ = S-formylglutathione + NADPH + H+." [RHEA:19981]
xref: RHEA:19981
is_a: GO:0051903 ! S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch RHEA:19981
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27135" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-09-23T15:26:27Z
@@ -451757,7 +468017,9 @@
def: "Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD+ = S-formylglutathione + NADH + H+." [RHEA:19985]
xref: RHEA:19985
is_a: GO:0051903 ! S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch RHEA:19985
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27135" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-09-23T15:26:40Z
@@ -451840,6 +468102,8 @@
def: "Catalysis of the reaction: H2O + L-phenylalanine + O2 = 3-phenylpyruvate + H2O2 + NH4(+)." [RHEA:61240]
xref: RHEA:61240
is_a: GO:0001716 ! L-amino-acid oxidase activity
+property_value: skos:exactMatch RHEA:61240
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-09-30T19:33:52Z
@@ -451851,6 +468115,8 @@
xref: MetaCyc:RXN-13182
xref: RHEA:22600
is_a: GO:0001681 ! sialate O-acetylesterase activity
+property_value: skos:exactMatch MetaCyc:RXN-13182
+property_value: skos:exactMatch RHEA:22600
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
created_by: hjd
creation_date: 2020-09-30T19:38:44Z
@@ -451863,6 +468129,8 @@
xref: MetaCyc:RXN-13181
xref: RHEA:25564
is_a: GO:0001681 ! sialate O-acetylesterase activity
+property_value: skos:exactMatch MetaCyc:RXN-13181
+property_value: skos:exactMatch RHEA:25564
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
created_by: hjd
creation_date: 2020-09-30T19:40:24Z
@@ -451896,6 +468164,8 @@
xref: RHEA:65764
is_a: GO:0016829 ! lyase activity
is_a: GO:0140097 ! catalytic activity, acting on DNA
+property_value: skos:exactMatch RHEA:65764
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-10-20T19:04:24Z
@@ -451907,7 +468177,10 @@
xref: EC:2.1.1.229
xref: RHEA:43208
is_a: GO:0016300 ! tRNA (uridine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.229
+property_value: skos:exactMatch RHEA:43208
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24975" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-10-27T21:34:30Z
@@ -451931,6 +468204,10 @@
xref: MetaCyc:RXN-11866
xref: RHEA:42932
is_a: GO:0016427 ! tRNA (cytidine) methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.200
+property_value: skos:broadMatch EC:2.1.1.205
+property_value: skos:exactMatch MetaCyc:RXN-11866
+property_value: skos:exactMatch RHEA:42932
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24771" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26018" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26086" xsd:anyURI
@@ -451947,6 +468224,7 @@
def: "Catalysis of the reaction: guanosine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(34) in tRNA + H+ + S-adenosyl-L-homocysteine." [PMID:31943105]
xref: Reactome:R-HSA-9024161 "FTSJ1 2'-O-methylates guanosine-34 in tRNA(Phe)"
is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.205
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25257" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26085" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26086" xsd:anyURI
@@ -451959,9 +468237,15 @@
id: GO:0106341
name: omega-hydroxyceramide transacylase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + N-(30-hydroxytriacontanoyl)-sphing-4-enine = di-(9Z,12Z)-octadecadienoylglycerol + N-[30-(9Z,12Z-octadecadienoyloxy)-triacontanoyl]-sphing-4-enine." [PMID:28248318, RHEA:55264]
-xref: RHEA:55264
+def: "Catalysis of the reaction: an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base + a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol = an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base + a diacylglycerol." [PMID:28248318, RHEA:61528]
+xref: EC:2.3.1.296
+xref: MetaCyc:RXN-20362
+xref: RHEA:61528
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.296
+property_value: skos:exactMatch MetaCyc:RXN-20362
+property_value: skos:exactMatch RHEA:61528
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: hjd
creation_date: 2020-11-17T17:12:43Z
@@ -451971,6 +468255,7 @@
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of omega-hydroxyceramide/acylceramide." [PMID:28248318]
is_a: GO:0046513 ! ceramide biosynthetic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20130" xsd:anyURI
created_by: hjd
creation_date: 2020-11-17T17:15:25Z
@@ -451982,6 +468267,9 @@
xref: EC:1.14.11.64
xref: RHEA:13821
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.64
+property_value: skos:exactMatch RHEA:13821
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-11-17T18:04:10Z
@@ -451992,7 +468280,9 @@
def: "Catalysis of the reaction: 2 Fe(3+) + 4 H2O + L-histidyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + N(6)-(pyridoxal phosphate)-L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] = (2S)-2-amino-5-hydroxy-4-oxopentanoyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 3-oxopropanoate + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 2 Fe(2+) + 2 H+ + L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase]." [PMID:22568620, RHEA:65756]
xref: RHEA:65756
is_a: GO:0016740 ! transferase activity
+property_value: skos:exactMatch RHEA:65756
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20274" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-12-04T14:48:37Z
@@ -452021,6 +468311,8 @@
def: "Catalysis of the reaction: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+." [PMID:31913360, RHEA:62672]
xref: RHEA:62672
is_a: GO:0106346 ! snRNA methyltransferase activity
+property_value: skos:exactMatch RHEA:62672
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2020-12-18T15:11:10Z
@@ -452056,8 +468348,11 @@
xref: EC:2.5.1.90
xref: RHEA:27798
is_a: GO:0120531 ! prenyl diphosphate synthase activity
+property_value: skos:exactMatch EC:2.5.1.90
+property_value: skos:exactMatch RHEA:27798
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29264" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-01-12T15:30:15Z
@@ -452078,6 +468373,8 @@
def: "Catalysis of the reaction: 4-hydroxybenzoate + H+ + NADH + O2 = 3,4-dihydroxybenzoate + H2O + NAD+." [RHEA:19473]
xref: RHEA:19473
is_a: GO:0018671 ! 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity
+property_value: skos:exactMatch RHEA:19473
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-02-02T05:51:36Z
@@ -452089,6 +468386,8 @@
synonym: "4-hydroxybenzoate 3-monooxygenase [NADPH] activity" EXACT []
xref: RHEA:19477
is_a: GO:0018671 ! 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity
+property_value: skos:exactMatch RHEA:19477
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-02-02T05:51:57Z
@@ -452100,6 +468399,8 @@
synonym: "glycerol-1-phosphate dehydrogenase [NAD+] activity" EXACT []
xref: RHEA:21412
is_a: GO:0050492 ! glycerol-1-phosphate dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch RHEA:21412
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-02-02T06:07:55Z
@@ -452111,6 +468412,8 @@
synonym: "glycerol-1-phosphate dehydrogenase [NADP+] activity" EXACT []
xref: RHEA:21416
is_a: GO:0050492 ! glycerol-1-phosphate dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch RHEA:21416
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-02-02T06:08:14Z
@@ -452120,7 +468423,14 @@
namespace: molecular_function
def: "Catalysis of the reaction: a 2-hydroxy fatty acyl-CoA = a fatty aldehyde + formyl-CoA. The reaction acts on 2-hydroxy-3-methyl-branched fatty acyl-CoA and 2-hydroxy-long-chain fatty acyl-CoA." [EC:4.1.2.63, PMID:21708296, PMID:28289220]
xref: EC:4.1.2.63
+xref: RHEA:25375
+xref: RHEA:25379
+xref: RHEA:67444
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:exactMatch EC:4.1.2.63
+property_value: skos:narrowMatch RHEA:25375
+property_value: skos:narrowMatch RHEA:25379
+property_value: skos:narrowMatch RHEA:67444
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20787" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23412" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25060" xsd:anyURI
@@ -452146,6 +468456,8 @@
def: "Catalysis of the reaction: dTDP-beta-L-rhamnose + L-arginyl-[protein] = dTDP + H+ + N(omega)-(L-rhamnosyl)-L-arginyl-[protein]." [GOC:sp, PMID:25686373, PMID:26060278, RHEA:66692]
xref: RHEA:66692
is_a: GO:0046527 ! glucosyltransferase activity
+property_value: skos:exactMatch RHEA:66692
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-02-05T15:39:52Z
@@ -452156,6 +468468,8 @@
def: "Catalysis of the reaction: L-arginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H+ + N(omega)-(N-acetyl-beta-D-glucosaminyl)-L-arginyl-[protein] + UDP." [GOC:sp, PMID:23955153, PMID:30619781, RHEA:66632]
xref: RHEA:66632
is_a: GO:0016262 ! protein N-acetylglucosaminyltransferase activity
+property_value: skos:exactMatch RHEA:66632
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-02-05T15:42:52Z
@@ -452170,6 +468484,8 @@
is_a: GO:0008172 ! S-methyltransferase activity
is_a: GO:0008276 ! protein methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch RHEA:66544
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-02-05T15:44:58Z
@@ -452180,8 +468496,12 @@
def: "Catalysis of the reaction: 4-hydroxy-3-all-trans-polyprenylbenzoate + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3,4-dihydroxy-5-all-trans-polyprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]." [PMID:38425362, RHEA:81195]
synonym: "4-hydroxy-3-all-trans-hexaprenylbenzoate oxygenase activity" NARROW []
xref: EC:1.14.15.45
+xref: MetaCyc:RXN3O-58
xref: RHEA:81195
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.15.45
+property_value: skos:exactMatch RHEA:81195
+property_value: skos:narrowMatch MetaCyc:RXN3O-58
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27952" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29459" xsd:anyURI
created_by: hjd
@@ -452195,6 +468515,9 @@
xref: EC:5.2.1.14
xref: RHEA:34455
is_a: GO:0016859 ! cis-trans isomerase activity
+property_value: skos:exactMatch EC:5.2.1.14
+property_value: skos:exactMatch RHEA:34455
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-02-16T15:32:24Z
@@ -452205,6 +468528,8 @@
def: "Catalysis of the reaction: ATP + guanosine = ADP + GMP." [PMID:10879466, PMID:7665468, RHEA:27710]
xref: RHEA:27710
is_a: GO:0019206 ! nucleoside kinase activity
+property_value: skos:broadMatch EC:2.7.1.73
+property_value: skos:exactMatch RHEA:27710
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27917" xsd:anyURI
created_by: hjd
creation_date: 2021-02-23T21:18:12Z
@@ -452217,6 +468542,8 @@
xref: RHEA:62128
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
is_a: GO:0019205 ! nucleobase-containing compound kinase activity
+property_value: skos:exactMatch RHEA:62128
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-03-11T20:06:53Z
@@ -452228,6 +468555,8 @@
xref: RHEA:62132
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
is_a: GO:0019205 ! nucleobase-containing compound kinase activity
+property_value: skos:exactMatch RHEA:62132
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-03-11T20:09:34Z
@@ -452239,6 +468568,8 @@
xref: RHEA:62124
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
is_a: GO:0019205 ! nucleobase-containing compound kinase activity
+property_value: skos:exactMatch RHEA:62124
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-03-11T20:12:21Z
@@ -452251,6 +468582,8 @@
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0008276 ! protein methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch RHEA:67076
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-03-22T15:13:06Z
@@ -452261,6 +468594,8 @@
def: "Catalysis of the reaction: O2 + primary fluorescent chlorophyll catabolite + reduced [NADPH--hemoprotein reductase] = formate + 2 H+ + oxidized [NADPH--hemoprotein reductase] + primary fluorescent dioxobilin-type chlorophyll catabolite." [PMID:23723324, RHEA:67172]
xref: RHEA:67172
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:67172
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-04-01T16:32:56Z
@@ -452271,6 +468606,8 @@
def: "Catalysis of the reaction: H2O + primary fluorescent dioxobilin-type chlorophyll catabolite = H+ + methanol + O13(4)-desmethyl pFCC." [PMID:23723324, RHEA:67176]
xref: RHEA:67176
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch RHEA:67176
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-04-01T16:53:38Z
@@ -452281,6 +468618,8 @@
def: "Catalysis of the reaction: 3-deoxyglucosone + H2O + NAD+ = 2-dehydro-3-deoxy-D-gluconate + 2 H+ + NADH." [PMID:17175089, RHEA:67244]
xref: RHEA:67244
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch RHEA:67244
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-04-12T14:48:12Z
@@ -452291,6 +468630,8 @@
def: "Catalysis of the reaction: dNTP + H2O = 2'-deoxynucleoside + H+ + triphosphate." [RHEA:46148]
xref: RHEA:46148
is_a: GO:0016793 ! triphosphoric monoester hydrolase activity
+property_value: skos:exactMatch RHEA:46148
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-04-15T20:44:33Z
@@ -452301,7 +468642,9 @@
def: "Catalysis of the reaction: 2-hydroxyphytanoyl-CoA = 2,6,10,14-tetramethylpentadecanal + formyl-CoA." [PMID:10468558, RHEA:25355]
xref: RHEA:25355
is_a: GO:0106359 ! 2-hydroxyacyl-CoA lyase activity
+property_value: skos:exactMatch RHEA:25355
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25060" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-04-16T12:47:53Z
@@ -452313,7 +468656,9 @@
xref: Reactome:R-HSA-2395872 "NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP"
xref: RHEA:67392
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:exactMatch RHEA:67392
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-04-23T00:12:31Z
@@ -452325,7 +468670,9 @@
xref: Reactome:R-HSA-2395818 "NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP"
xref: RHEA:31583
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:exactMatch RHEA:31583
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-04-23T00:14:20Z
@@ -452336,6 +468683,7 @@
def: "Catalysis of the reaction: 8-oxo-(d)RTP + H20 = 8-oxo-(d)RMP + diphosphate + H+." [PMID:11139615]
xref: Reactome:R-HSA-9731228 "NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP"
is_a: GO:0047429 ! nucleoside triphosphate diphosphatase activity
+property_value: skos:broadMatch EC:3.6.1.9
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: hjd
@@ -452402,6 +468750,8 @@
xref: MetaCyc:RXN66-485
xref: RHEA:32711
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.n12
+property_value: skos:exactMatch RHEA:32711
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30577" xsd:anyURI
created_by: hjd
@@ -452424,10 +468774,13 @@
def: "Catalysis of the reaction: N1-methylpseudouridine in small subunit rRNA + S-adenosyl-L-methionine = H+ + N1-methyl-N3-[(3S)-3-amino-3-carboxypropyl]pseudouridine in small subunit rRNA + S-methyl-5'-thioadenosine." [PMID:27084949, RHEA:63296]
synonym: "18S rRNA aminocarboxypropyltransferase activity" NARROW []
xref: EC:2.5.1.157
-xref: RHEA:63296 {comment="skos:exactMatch"}
+xref: RHEA:63296
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
is_a: GO:0140102 ! catalytic activity, acting on a rRNA
+property_value: skos:exactMatch EC:2.5.1.157
+property_value: skos:exactMatch RHEA:63296
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29843" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-07-13T14:01:28Z
@@ -452440,7 +468793,9 @@
xref: MetaCyc:RXN-14755
xref: RHEA:67972
is_a: GO:0016301 ! kinase activity
+property_value: skos:exactMatch RHEA:67972
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21632" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-07-13T14:37:23Z
@@ -452596,7 +468951,12 @@
comment: Trims Glc alpha 1,3 Glc bond in Glc2Man9GlcNAc2 oligosaccharide in inmature glycoproteins.
synonym: "glucosidase II" BROAD []
xref: EC:3.2.1.207
+xref: RHEA:55996
+xref: RHEA:56000
is_a: GO:0090599 ! alpha-glucosidase activity
+property_value: skos:exactMatch EC:3.2.1.207
+property_value: skos:narrowMatch RHEA:55996
+property_value: skos:narrowMatch RHEA:56000
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28029" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28242" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28502" xsd:anyURI
@@ -452613,6 +468973,9 @@
xref: MetaCyc:RXN-14338
xref: RHEA:35655
is_a: GO:0016779 ! nucleotidyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.85
+property_value: skos:exactMatch RHEA:35655
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-10-29T14:53:01Z
@@ -452625,6 +468988,9 @@
xref: MetaCyc:RXN-19814
xref: RHEA:54420
is_a: GO:0016779 ! nucleotidyltransferase activity
+property_value: skos:exactMatch EC:3.1.4.59
+property_value: skos:exactMatch RHEA:54420
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-10-29T14:57:11Z
@@ -452657,7 +469023,11 @@
name: RNA dihydrouridine synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: RNA-uracil + NAD(P)+ = RNA-dihydrouridine + NAD(P)H + H+." [PMID:12581659, PMID:25073379]
+xref: RHEA:69843
+xref: RHEA:69847
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:narrowMatch RHEA:69843
+property_value: skos:narrowMatch RHEA:69847
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27519" xsd:anyURI
created_by: hjd
creation_date: 2021-12-08T16:34:41Z
@@ -452667,7 +469037,11 @@
name: mRNA dihydrouridine synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: mRNA-uracil + NAD(P)+ = mRNA-dihydrouridine + NAD(P)H+ + H+." [PMID:34798057]
+xref: RHEA:69851
+xref: RHEA:69855
is_a: GO:0106413 ! RNA dihydrouridine synthase activity
+property_value: skos:narrowMatch RHEA:69851
+property_value: skos:narrowMatch RHEA:69855
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27519" xsd:anyURI
created_by: hjd
creation_date: 2021-12-08T16:36:19Z
@@ -452680,6 +469054,9 @@
xref: EC:3.4.17.13
xref: RHEA:48688
is_a: GO:0004180 ! carboxypeptidase activity
+property_value: skos:exactMatch EC:3.4.17.13
+property_value: skos:exactMatch RHEA:48688
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2021-12-21T14:33:53Z
@@ -452690,6 +469067,8 @@
def: "Catalysis of the reaction: dopaminechrome = 5,6-dihydroxyindole." [PMID:34388859, RHEA:70199]
xref: RHEA:70199
is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds
+property_value: skos:exactMatch RHEA:70199
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2022-01-06T14:51:16Z
@@ -452702,6 +469081,9 @@
xref: EC:6.3.2.45
xref: RHEA:29563
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.45
+property_value: skos:exactMatch RHEA:29563
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2022-01-18T14:57:30Z
@@ -452714,7 +469096,10 @@
xref: MetaCyc:RXN-22964
xref: RHEA:63640
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch EC:2.3.1.313
+property_value: skos:exactMatch RHEA:63640
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27533" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2022-02-24T17:53:27Z
@@ -452725,6 +469110,7 @@
def: "Catalysis of the reaction: H2O + N6-biotinyl-L-lysyl-[protein] + NAD+ = 2''-O-biotinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide." [PMID:25525879, RHEA:70479]
xref: RHEA:70479
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch RHEA:70479
created_by: hjd
creation_date: 2022-02-24T17:55:29Z
@@ -452747,19 +469133,24 @@
xref: EC:1.13.11.65
xref: RHEA:33931
is_a: GO:0010436 ! carotenoid dioxygenase activity
+property_value: skos:exactMatch EC:1.13.11.65
+property_value: skos:exactMatch RHEA:33931
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23234" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2022-04-29T17:37:22Z
[Term]
id: GO:0106423
-name: tubulin-tyrosine carboxypeptidase
+name: tubulin-tyrosine carboxypeptidase activity
namespace: molecular_function
def: "Catalysis of the reaction: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H2O = C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine." [PMID:29146869, PMID:35482892, RHEA:57444]
synonym: "tubulinyl-Tyr carboxypeptidase" EXACT [EC:3.4.17.17]
xref: EC:3.4.17.17
xref: RHEA:57444
is_a: GO:0004181 ! metallocarboxypeptidase activity
+property_value: skos:exactMatch EC:3.4.17.17
+property_value: skos:exactMatch RHEA:57444
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23419" xsd:anyURI
created_by: hjd
creation_date: 2022-05-31T13:19:27Z
@@ -452773,7 +469164,10 @@
xref: EC:4.1.1.107
xref: RHEA:55524
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.107
+property_value: skos:exactMatch RHEA:55524
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23528" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2022-06-22T13:25:19Z
@@ -452825,6 +469219,8 @@
xref: EC:1.1.1.315
xref: RHEA:55668
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.1.1.315
+property_value: skos:exactMatch RHEA:55668
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23669" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30275" xsd:anyURI
created_by: hjd
@@ -452839,7 +469235,10 @@
xref: RHEA:30187
is_a: GO:0004152 ! dihydroorotate dehydrogenase activity
is_a: GO:0016635 ! oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor
+property_value: skos:exactMatch EC:1.3.5.2
+property_value: skos:exactMatch RHEA:30187
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23786" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2022-07-26T19:27:20Z
@@ -452848,7 +469247,11 @@
name: N6-methyl-(d)ATP hydrolase activity
namespace: molecular_function
def: "Catalysis of the reaction N6-methyl-(d)ATP + H2O = N6-methyl-(d)AMP + diphosphate + H+." [PMID:32144205]
+xref: RHEA:67604
+xref: RHEA:67608
is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
+property_value: skos:narrowMatch RHEA:67604
+property_value: skos:narrowMatch RHEA:67608
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21498" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21499" xsd:anyURI
created_by: hjd
@@ -452863,6 +469266,7 @@
synonym: "tRNA queuosine nucleoside glycosylase" EXACT []
xref: RHEA:75387
is_a: GO:0008477 ! purine nucleosidase activity
+property_value: skos:exactMatch RHEA:75387
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23846" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29892" xsd:anyURI
created_by: hjd
@@ -452875,7 +469279,9 @@
def: "Catalysis of the reaction O6-methyl-dGTP + H2O = O6-methyl-dGMP + diphosphate + H+." [PMID:30304478, RHEA:67600]
xref: RHEA:67600
is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
+property_value: skos:exactMatch RHEA:67600
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21497" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2022-09-16T18:24:35Z
@@ -452912,7 +469318,10 @@
xref: Reactome:R-HSA-9749647 "CES2 hydrolyzes ASA-"
xref: RHEA:21164
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:exactMatch EC:3.1.1.1
+property_value: skos:exactMatch RHEA:21164
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21843" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2022-10-03T21:37:41Z
@@ -452925,7 +469334,10 @@
xref: EC:1.8.5.8
xref: RHEA:55156
is_a: GO:0016672 ! oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.8.5.8
+property_value: skos:exactMatch RHEA:55156
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23325" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2022-10-07T00:15:41Z
@@ -452936,6 +469348,7 @@
def: "Catalytic reaction: ATP + L-glutamate + L-glutamyl-[protein] = ADP + H+ + L-gamma-glutamyl-L-glutamyl-[protein] + phosphate." [PMID:32747782, RHEA:60144]
xref: RHEA:60144
is_a: GO:0070739 ! protein-glutamic acid ligase activity
+property_value: skos:exactMatch RHEA:60144
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21309" xsd:anyURI
created_by: hjd
creation_date: 2022-10-21T21:11:47Z
@@ -452947,6 +469360,7 @@
def: "Catalytic reaction :(L-glutamyl)n-L-gamma-glutamyl-L-glutamyl-[protein] + ATP + L-glutamate = (L-glutamyl)n+1-L-gamma-glutamyl-L-glutamyl-[protein] + ADP + H+ + phosphate." [PMID:32747782, RHEA:60148]
xref: RHEA:60148
is_a: GO:0070739 ! protein-glutamic acid ligase activity
+property_value: skos:exactMatch RHEA:60148
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21309" xsd:anyURI
created_by: hjd
creation_date: 2022-10-21T21:15:15Z
@@ -452961,7 +469375,9 @@
is_a: GO:0015189 ! L-lysine transmembrane transporter activity
is_a: GO:0015297 ! antiporter activity
is_a: GO:0061459 ! L-arginine transmembrane transporter activity
+property_value: skos:exactMatch RHEA:70827
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24324" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2022-11-08T21:55:18Z
@@ -453508,7 +469924,10 @@
xref: EC:3.5.1.128
xref: RHEA:54532
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.128
+property_value: skos:exactMatch RHEA:54532
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23261" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: kmv
creation_date: 2017-08-31T19:19:11Z
@@ -453701,8 +470120,15 @@
id: GO:0110068
name: glucosylglycerate phosphorylase activity
namespace: molecular_function
-def: "Catalysis of the reaction: glucosylglycerate + phosphate = glucose-1-phosphate + D-glycerate." [GOC:imk, PMID:28754708]
+def: "Catalysis of the reaction: (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + phosphate = (R)-glycerate + alpha-D-glucose 1-phosphate." [PMID:28754708, RHEA:55268]
+xref: EC:2.4.1.352
+xref: MetaCyc:RXN-18999
+xref: RHEA:55268
is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity
+property_value: skos:exactMatch EC:2.4.1.352
+property_value: skos:exactMatch MetaCyc:RXN-18999
+property_value: skos:exactMatch RHEA:55268
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: kmv
creation_date: 2017-11-21T21:50:10Z
@@ -453894,15 +470320,13 @@
[Term]
id: GO:0110084
-name: negative regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly
+name: obsolete negative regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly
namespace: biological_process
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly." [GOC:vw, PMID:29343550]
-is_a: GO:0110082 ! regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly
-is_a: GO:1903500 ! negative regulation of mitotic actomyosin contractile ring assembly
-is_a: GO:1903828 ! negative regulation of protein localization
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:1903476 ! protein localization to cell division site involved in mitotic actomyosin contractile ring assembly
-relationship: negatively_regulates GO:1903476 ! protein localization to cell division site involved in mitotic actomyosin contractile ring assembly
+def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly." [GOC:vw, PMID:29343550]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:1903475
created_by: kmv
creation_date: 2018-02-01T19:33:51Z
@@ -454408,6 +470832,8 @@
def: "Catalysis of the reaction: ribitol-5-phosphate + H20 = ribitol + phosphate." [GOC:rn, PMID:30240188]
xref: RHEA:47648
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch RHEA:47648
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: kmv
creation_date: 2018-10-08T19:47:57Z
@@ -454601,7 +471027,6 @@
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29105" xsd:anyURI
is_obsolete: true
replaced_by: GO:0051604
-consider: GO:0170061
created_by: kmv
creation_date: 2019-05-31T14:41:20Z
@@ -454677,8 +471102,10 @@
xref: RHEA:60880
is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
is_a: GO:0140098 ! catalytic activity, acting on RNA
+property_value: skos:exactMatch RHEA:60880
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17594" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: kmv
creation_date: 2019-07-08T15:55:11Z
@@ -454691,8 +471118,10 @@
xref: RHEA:60876
is_a: GO:0016462 ! pyrophosphatase activity
is_a: GO:0140098 ! catalytic activity, acting on RNA
+property_value: skos:exactMatch RHEA:60876
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17594" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23401" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: kmv
creation_date: 2019-07-08T17:15:59Z
@@ -454989,10 +471418,6 @@
def: "Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198]
synonym: "intermembrane lipid transfer activity" EXACT []
synonym: "lipid carrier activity" EXACT []
-xref: Reactome:R-HSA-8856630 "CIDEA:CIDEC binds lipid droplets"
-xref: Reactome:R-HSA-8858270 "HILPDA binds lipid droplets"
-xref: Reactome:R-HSA-8862380 "HSD17B13 binds lipid droplets"
-xref: Reactome:R-HSA-8874705 "TTPA transports alpha-TOH from lysosomal membrane to plasma membrane"
xref: Reactome:R-HSA-9856502 "mito-STARD7 transports Q10 to outer mitochondrial membrane"
xref: Reactome:R-HSA-9856510 "STARD7 transports Q10 to plasma membrane"
is_a: GO:0005319 ! lipid transporter activity
@@ -455056,7 +471481,6 @@
synonym: "ceramide carrier activity" EXACT []
synonym: "ceramide transporter activity" BROAD []
synonym: "intermembrane ceramide transfer activity" NARROW []
-xref: Reactome:R-HSA-9956909 "CERT1-2 transfers CERA from the ER membrane to the Golgi membrane"
is_a: GO:0120016 ! sphingolipid transfer activity
relationship: has_part GO:0097001 ! ceramide binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/12329" xsd:anyURI
@@ -455073,7 +471497,6 @@
xref: Reactome:R-HSA-1483087 "PI is exchanged with PC by PITPNB"
xref: Reactome:R-HSA-1483211 "PC:PITPNB is transported from the Golgi membrane to the ER membrane"
xref: Reactome:R-HSA-1483219 "PC is exchanged with PI by PITPNB"
-xref: Reactome:R-HSA-9956308 "STARD7 transports PC from ER membrane to mitochondrial outer membrane"
is_a: GO:0008525 ! phosphatidylcholine transporter activity
is_a: GO:0120014 ! phospholipid transfer activity
relationship: has_part GO:0031210 ! phosphatidylcholine binding
@@ -455422,8 +471845,11 @@
xref: MetaCyc:RXN-18779
xref: RHEA:52808
is_a: GO:0106346 ! snRNA methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.346
+property_value: skos:exactMatch RHEA:52808
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/13569" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27391" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2017-06-02T20:37:40Z
@@ -455442,7 +471868,6 @@
name: ribitol beta-1,4-xylosyltransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: UDP-D-xylose + D-ribitol 5-phosphate-R = UDP + beta1,4-xylosyl-D-ribitol 5-phosphate-R." [PMID:27733679]
-xref: Reactome:R-HSA-9940805 "RXYLT1 transfers initial Xyl to matriglycan chain"
is_a: GO:0035252 ! UDP-xylosyltransferase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/13641" xsd:anyURI
created_by: krc
@@ -455896,21 +472321,31 @@
id: GO:0120086
name: (3S)-(+)-asterisca-2(9),6-diene synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (3S)-(+)-asterisca-2(9),6-diene." [PMID:27862766]
+def: "Catalysis of the reaction: (2E,6E)-farnesyl diphosphate = (3S)-(+)-asterisca-2(9),6-diene + diphosphate." [PMID:27862766, RHEA:53632]
synonym: "asterisca-2(9),6-diene synthase activity" BROAD []
+xref: EC:4.2.3.161
+xref: MetaCyc:RXN-18788
+xref: RHEA:53632
is_a: GO:0010334 ! sesquiterpene synthase activity
+property_value: skos:exactMatch EC:4.2.3.161
+property_value: skos:exactMatch MetaCyc:RXN-18788
+property_value: skos:exactMatch RHEA:53632
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14003" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: krc
creation_date: 2017-08-02T14:55:38Z
[Term]
id: GO:0120091
-name: jasmonic acid hydrolase
+name: jasmonic acid hydrolase activity
namespace: molecular_function
-def: "Catalyzes the hydroxylation of jasmonic acid to 12OH-jasmonic acid." [PMID:28559313, PMID:28760569]
+def: "Catalysis of the reaction: jasmonate + 2-oxoglutarate + O2 = (1R,2R)-12-hydroxyjasmonate + succinate + CO2." [PMID:28559313, PMID:28760569, RHEA:67144]
synonym: "2-oxoglutarate dioxygenase" BROAD []
+xref: RHEA:67144
is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
+property_value: skos:exactMatch RHEA:67144
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14065" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2017-08-18T23:25:52Z
@@ -455922,8 +472357,10 @@
synonym: "crotonyl-CoA hydratase activity" EXACT []
xref: RHEA:45584
is_a: GO:0018812 ! 3-hydroxyacyl-CoA dehydratase activity
+property_value: skos:exactMatch RHEA:45584
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14109" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29789" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2017-08-22T20:13:55Z
@@ -456109,6 +472546,8 @@
xref: EC:3.6.1.72
xref: RHEA:52140
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.72
+property_value: skos:exactMatch RHEA:52140
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14348" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30724" xsd:anyURI
created_by: krc
@@ -456409,8 +472848,10 @@
synonym: "dUMP-kinase activity" EXACT []
xref: RHEA:30655
is_a: GO:0047507 ! deoxynucleoside phosphate kinase activity, ATP as phosphate donor
+property_value: skos:exactMatch RHEA:30655
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/15447" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29533" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2018-03-21T21:16:06Z
@@ -456543,7 +472984,10 @@
xref: MetaCyc:RXN-16226
xref: RHEA:51152
is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor
+property_value: skos:exactMatch EC:1.8.3.7
+property_value: skos:exactMatch RHEA:51152
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/15520" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2018-04-06T15:38:52Z
@@ -456688,8 +473132,10 @@
xref: RHEA:54568
is_a: GO:0009982 ! pseudouridine synthase activity
is_a: GO:0140098 ! catalytic activity, acting on RNA
+property_value: skos:exactMatch RHEA:54568
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/15632" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26618" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2018-05-11T21:24:19Z
@@ -456713,7 +473159,6 @@
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cold-induced thermogenesis." [PMID:27876809]
synonym: "regulation of CIT" RELATED []
-is_a: GO:0019222 ! regulation of metabolic process
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0106106 ! cold-induced thermogenesis
@@ -456728,7 +473173,6 @@
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis." [PMID:27876809]
synonym: "positive regulation of CIT" RELATED []
-is_a: GO:0009893 ! positive regulation of metabolic process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:0120161 ! regulation of cold-induced thermogenesis
intersection_of: GO:0065007 ! biological regulation
@@ -456744,7 +473188,6 @@
namespace: biological_process
def: "Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis." [PMID:27876809]
synonym: "negative regulation of CIT" RELATED []
-is_a: GO:0009892 ! negative regulation of metabolic process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:0120161 ! regulation of cold-induced thermogenesis
intersection_of: GO:0065007 ! biological regulation
@@ -456878,8 +473321,8 @@
comment: Note, although the SHRED pathway may contain some components in common with ER-associated protein degradation (ERAD) pathways (GO:0036503), such as UBR1, RAD6 and CDC48, other ERAD components, such as HRD1 and DOA10 do not appear to be involved, and as such these pathways are currently considered to be distinct. ERAD pathways target misfolded ER lumenal proteins (ERAD-L), ER membrane proteins (ERAD-M) and ER proteins with misfolded cytosolic domains (ERAD-C) by recognizing aberrant proteins, retrotranslocating these substrates to the cytosol, followed by subsequent substrate ubiquitination and proteosome-mediated degradation. In contrast the SHRED pathway, although inducible by stress, targets diverse ER membrane and cytosolic proteins as well as numerous other native proteins in the absence of stress. In the SHRED pathway an Nma111p serine protease-mediated cleavage results in the generation of a Roq1p fragment that then binds to the type-1 active site of Ubr1p, altering its substrate specificity, and leading to the proteasome-mediated degradation of both misfolded and native proteins. SHRED is also considered to be distinct from the endoplasmic reticulum unfolded protein response (GO:0030968), a process by which ER stress activates the ER membrane protein Ire1p, resulting in splicing of the HAC1 mRNA, followed by Hac1p-mediated up-regulation of UPR genes. Induction of SHRED does not require IRE1 or HAC1, and as such is currently considered to be distinct.
synonym: "SHRED pathway" RELATED [GOC:rn]
is_a: GO:0033554 ! cellular response to stress
+is_a: GO:0042221 ! response to chemical
is_a: GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process
-is_a: GO:1901698 ! response to nitrogen compound
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/15869" xsd:anyURI
created_by: krc
creation_date: 2018-06-07T16:16:43Z
@@ -457287,7 +473730,11 @@
name: methylcytosine to 5-glyceryl-methylcytosine dioxygenase activity
namespace: molecular_function
def: "Catalysis of the reaction: methylcytosine + L-ascorbate + O2 = 5-glyceryl-methylcytosine + glyoxylate + CO2." [PMID:31043749]
+xref: RHEA:60132
+xref: RHEA:60136
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
+property_value: skos:narrowMatch RHEA:60132
+property_value: skos:narrowMatch RHEA:60136
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17267" xsd:anyURI
created_by: krc
creation_date: 2019-05-10T15:58:47Z
@@ -457488,15 +473935,16 @@
id: GO:0120216
name: matrilin complex
namespace: cellular_component
-def: "A cartilage extracellular matrix complex that mediates interactions between major components of the extracellular matrix such as collagens and proteoglycans and contributes to their fibrillar network. Exists as an obligate homotrimer." [GOC:bhm, PMID:10367731, PMID:15075323, PMID:9699631]
+def: "A cartilage extracellular matrix complex that mediates interactions between major components of the extracellular matrix such as collagens and proteoglycans and contributes to their fibrillar network. Exists as an obligate homotrimer." [PMID:10367731, PMID:15075323, PMID:15094109, PMID:9699631]
synonym: "matrilin family complex" RELATED [GOC:bhm]
synonym: "matrilin-1 complex" NARROW [GOC:bhm]
synonym: "matrilin-2 complex" NARROW [GOC:bhm]
synonym: "matrilin-3 complex" NARROW [GOC:bhm]
synonym: "matrilin-4 complex" NARROW [GOC:bhm]
is_a: GO:0032991 ! protein-containing complex
-relationship: part_of GO:0031012 ! extracellular matrix
+relationship: part_of GO:0140149 ! non-collagenous component of interstitial matrix
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17598" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31067" xsd:anyURI
created_by: krc
creation_date: 2019-07-09T22:05:11Z
@@ -457598,7 +474046,6 @@
namespace: molecular_function
def: "Binding to coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester." [GOC:krc, ISBN:0198547684]
synonym: "CoA binding" EXACT []
-is_a: GO:0033218 ! amide binding
is_a: GO:0043168 ! anion binding
is_a: GO:1901265 ! nucleoside phosphate binding
is_a: GO:1901363 ! heterocyclic compound binding
@@ -457625,7 +474072,6 @@
def: "Binding to an acyl-CoA, a thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid." [GOC:krc]
synonym: "acyl binding" BROAD []
synonym: "acyl-coenzyme A binding" EXACT []
-is_a: GO:0033218 ! amide binding
is_a: GO:0043168 ! anion binding
is_a: GO:1901265 ! nucleoside phosphate binding
is_a: GO:1901363 ! heterocyclic compound binding
@@ -457815,7 +474261,7 @@
[Term]
id: GO:0120241
-name: 2-iminobutanoate/2-iminopropanoate deaminase
+name: 2-iminobutanoate/2-iminopropanoate deaminase activity
namespace: molecular_function
def: "Catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17." [EC:3.5.99.10]
comment: This enzyme, which has been found in all species and tissues examined, catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17. The reactions, which can occur spontaneously, are accelerated to minimize the cellular damage that could be caused by these reactive intermediates (from EC:3.5.99.10).
@@ -457825,7 +474271,9 @@
synonym: "imine intermediate deaminase activity" RELATED [] {comment="EC:3.5.99.10"}
xref: EC:3.5.99.10
is_a: GO:0019239 ! deaminase activity
+property_value: skos:exactMatch EC:3.5.99.10
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19832" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2020-07-29T17:28:19Z
@@ -457837,10 +474285,11 @@
synonym: "2-iminobutanoate/2-iminopropanoate deaminase" BROAD [EC:3.5.99.10]
xref: KEGG_REACTION:R11098
xref: MetaCyc:RXN-15123
-xref: Reactome:R-HSA-9014641 "HRSP12 deaminates 2-iminobutanoate to 2OBUTA"
xref: RHEA:39975
-is_a: GO:0120241 ! 2-iminobutanoate/2-iminopropanoate deaminase
+is_a: GO:0120241 ! 2-iminobutanoate/2-iminopropanoate deaminase activity
+property_value: skos:exactMatch RHEA:39975
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19832" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2020-07-29T18:07:00Z
@@ -457853,8 +474302,10 @@
xref: KEGG_REACTION:R11099
xref: MetaCyc:RXN-15127
xref: RHEA:40671
-is_a: GO:0120241 ! 2-iminobutanoate/2-iminopropanoate deaminase
+is_a: GO:0120241 ! 2-iminobutanoate/2-iminopropanoate deaminase activity
+property_value: skos:exactMatch RHEA:40671
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19832" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2020-07-29T19:41:18Z
@@ -457956,9 +474407,12 @@
synonym: "omega-hydroxylase activity" BROAD [EC:1.14.15.3]
xref: RHEA:39023
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:broadMatch EC:1.14.15.3
+property_value: skos:exactMatch RHEA:39023
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19899" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24664" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27756" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2020-09-01T00:19:13Z
@@ -458578,7 +475032,9 @@
def: "Catalysis of the reaction: L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4(+)." [GOC:sp, PMID:14697203]
xref: RHEA:66552
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch RHEA:66552
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20685" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2021-01-19T02:07:56Z
@@ -458589,6 +475045,7 @@
def: "Catalysis of the reaction: L-glutaminyl-[histone] + serotonin = 5-serotonyl-L-glutamyl-[histone] + NH4(+)." [GOC:sp, PMID:30867594]
is_a: GO:0120294 ! peptide serotonyltransferase activity
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:broadMatch RHEA:66552
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20685" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: krc
@@ -458601,7 +475058,9 @@
def: "Catalysis of the reaction: dopamine + L-glutaminyl-[protein] = 5-dopaminyl-L-glutamyl-[protein] + NH4(+)." [GOC:sp, PMID:22858378, PMID:32273471]
xref: RHEA:66556
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch RHEA:66556
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20685" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2021-01-19T02:20:30Z
@@ -458612,6 +475071,7 @@
def: "Catalysis of the reaction: dopamine + L-glutaminyl-[histone] = 5-dopaminyl-L-glutamyl-[histone] + NH4(+)." [GOC:sp, PMID:32273471]
is_a: GO:0120296 ! peptide dopaminyltransferase activity
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:broadMatch RHEA:66556
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20685" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: krc
@@ -458624,7 +475084,9 @@
def: "Catalysis of the reaction: (R)-noradrenaline + L-glutaminyl-[protein] = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4(+)." [GOC:sp, PMID:22858378]
xref: RHEA:66560
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch RHEA:66560
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20685" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2021-01-19T03:20:26Z
@@ -458635,7 +475097,9 @@
def: "Catalysis of the reaction: histamine + L-glutaminyl-[protein] = 5-histaminyl-L-glutamyl-[protein]." [GOC:sp, PMID:23022564, PMID:23797785]
xref: RHEA:66564
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch RHEA:66564
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20685" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2021-01-19T03:23:48Z
@@ -458649,8 +475113,10 @@
synonym: "peptide lactyltransferase activity (CoA-dependent)" BROAD []
xref: RHEA:61996
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch RHEA:61996
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20685" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28015" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2021-01-19T03:35:54Z
@@ -458664,6 +475130,7 @@
synonym: "histone lactyltransferase activity (CoA dependent)" EXACT []
is_a: GO:0120300 ! peptide lactyltransferase (CoA-dependent) activity
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:broadMatch RHEA:61996
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20685" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28015" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -458905,7 +475372,9 @@
synonym: "cytochrome P450 fatty acid omega-1 hydroxylase activity" RELATED []
xref: RHEA:60936
is_a: GO:0120502 ! fatty acid omega-1 hydroxylase activity
+property_value: skos:exactMatch RHEA:60936
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21648" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: krc
creation_date: 2021-06-21T18:31:38Z
@@ -459006,9 +475475,10 @@
xref: RHEA:68984
is_a: GO:0003886 ! DNA (cytosine-5-)-methyltransferase activity
is_a: GO:0008094 ! ATP-dependent activity, acting on DNA
-intersection_of: GO:0003886 ! DNA (cytosine-5-)-methyltransferase activity
-intersection_of: has_part GO:0016887 ! ATP hydrolysis activity
+property_value: skos:exactMatch RHEA:68984
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21872" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
created_by: krc
creation_date: 2021-08-16T21:00:16Z
@@ -459216,7 +475686,10 @@
xref: EC:1.14.13.225
xref: RHEA:51308
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.225
+property_value: skos:exactMatch RHEA:51308
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27530" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2024-04-25T13:46:24Z
@@ -459227,7 +475700,9 @@
def: "Catalysis of the reaction: an (omega-1)-ethyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an (omega-1)-hydroxy fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase]." [RHEA:44548]
xref: RHEA:44548
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch RHEA:44548
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24661" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2024-04-26T10:00:25Z
@@ -459262,7 +475737,9 @@
comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
xref: RHEA:60332
is_a: GO:0031151 ! histone H3K79 methyltransferase activity
+property_value: skos:exactMatch RHEA:60332
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26657" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: sjm
creation_date: 2024-04-30T12:26:45Z
@@ -459310,7 +475787,9 @@
xref: MetaCyc:RXN0-300
xref: RHEA:18657
is_a: GO:0016618 ! hydroxypyruvate reductase [NAD(P)H] activity
+property_value: skos:exactMatch RHEA:18657
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25789" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2024-05-10T14:03:36Z
@@ -459337,7 +475816,10 @@
xref: MetaCyc:RXN-11621
xref: RHEA:43728
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.127
+property_value: skos:exactMatch RHEA:43728
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27938" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2024-05-23T12:38:07Z
@@ -459351,7 +475833,10 @@
xref: MetaCyc:RXN-11770
xref: RHEA:43724
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.128
+property_value: skos:exactMatch RHEA:43724
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27938" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2024-05-23T12:38:32Z
@@ -459375,6 +475860,9 @@
xref: MetaCyc:RXN-18732
xref: RHEA:51504
is_a: GO:0016758 ! hexosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.360
+property_value: skos:exactMatch MetaCyc:RXN-18732
+property_value: skos:exactMatch RHEA:51504
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28159" xsd:anyURI
created_by: sjm
creation_date: 2024-06-18T10:22:10Z
@@ -459388,6 +475876,8 @@
xref: RHEA:38883
is_a: GO:0015645 ! fatty acid ligase activity
is_a: GO:0016405 ! CoA-ligase activity
+property_value: skos:exactMatch MetaCyc:BUTYRATE--COA-LIGASE-RXN
+property_value: skos:exactMatch RHEA:38883
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
created_by: sjm
creation_date: 2024-06-25T12:17:07Z
@@ -459400,6 +475890,9 @@
xref: MetaCyc:RXN-19279
xref: RHEA:32731
is_a: GO:0016298 ! lipase activity
+property_value: skos:broadMatch EC:3.1.1.79
+property_value: skos:exactMatch MetaCyc:RXN-19279
+property_value: skos:exactMatch RHEA:32731
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28339" xsd:anyURI
created_by: sjm
creation_date: 2024-06-28T12:36:24Z
@@ -459421,8 +475914,17 @@
namespace: molecular_function
def: "Catalysis of the reaction: acetyl-CoA + N-terminal L-methionyl-[protein] = CoA + H+ + N-terminal N(alpha)-acetyl-L-methionyl-[protein]." [RHEA:75239]
synonym: "peptide-methionine-alpha-N-acetyltransferase activity" EXACT []
+xref: EC:2.3.1.254
+xref: EC:2.3.1.256
+xref: EC:2.3.1.258
+xref: EC:2.3.1.259
xref: RHEA:75239
is_a: GO:0004596 ! protein-N-terminal amino-acid acetyltransferase activity
+property_value: skos:exactMatch RHEA:75239
+property_value: skos:narrowMatch EC:2.3.1.254
+property_value: skos:narrowMatch EC:2.3.1.256
+property_value: skos:narrowMatch EC:2.3.1.258
+property_value: skos:narrowMatch EC:2.3.1.259
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27532" xsd:anyURI
created_by: sjm
creation_date: 2024-07-10T12:16:39Z
@@ -459438,6 +475940,10 @@
xref: MetaCyc:RXN-22633
xref: RHEA:69607
is_a: GO:0004596 ! protein-N-terminal amino-acid acetyltransferase activity
+property_value: skos:exactMatch EC:2.3.1.308
+property_value: skos:exactMatch KEGG_REACTION:R12978
+property_value: skos:exactMatch MetaCyc:RXN-22633
+property_value: skos:exactMatch RHEA:69607
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27532" xsd:anyURI
created_by: sjm
creation_date: 2024-07-10T12:20:19Z
@@ -459449,6 +475955,7 @@
def: "Catalysis of the reaction: a 1,2-saturated fatty acid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = a (R)-2-hydroxy fatty acid + 2 Fe(III)-[cytochrome b5] + H2O. Note that the substrate is a free fatty acid, not a fatty acyl chain within a sphingolipid." [GOC:sjm, RHEA:38855]
xref: RHEA:38855
is_a: GO:0080132 ! fatty acid 2-hydroxylase activity
+property_value: skos:exactMatch RHEA:38855
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27541" xsd:anyURI
created_by: sjm
creation_date: 2024-07-12T08:40:48Z
@@ -459461,6 +475968,9 @@
xref: MetaCyc:RXN3O-4042
xref: RHEA:46520
is_a: GO:0080132 ! fatty acid 2-hydroxylase activity
+property_value: skos:broadMatch EC:1.14.18.6
+property_value: skos:exactMatch MetaCyc:RXN3O-4042
+property_value: skos:exactMatch RHEA:46520
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27541" xsd:anyURI
created_by: sjm
creation_date: 2024-07-12T08:47:01Z
@@ -459473,7 +475983,9 @@
comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
xref: RHEA:78859
is_a: GO:0003997 ! acyl-CoA oxidase activity
+property_value: skos:exactMatch RHEA:78859
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28733" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2024-08-27T08:19:22Z
@@ -459485,7 +475997,9 @@
comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
xref: RHEA:78855
is_a: GO:0003997 ! acyl-CoA oxidase activity
+property_value: skos:exactMatch RHEA:78855
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28733" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2024-08-27T08:21:49Z
@@ -459497,7 +476011,9 @@
comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
xref: RHEA:78851
is_a: GO:0003997 ! acyl-CoA oxidase activity
+property_value: skos:exactMatch RHEA:78851
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28733" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2024-08-27T08:24:03Z
@@ -459512,6 +476028,11 @@
xref: MetaCyc:RXN-13946
xref: RHEA:35095
is_a: GO:0016840 ! carbon-nitrogen lyase activity
+property_value: skos:exactMatch EC:4.3.99.4
+property_value: skos:exactMatch KEGG_REACTION:R10285
+property_value: skos:exactMatch MetaCyc:RXN-13946
+property_value: skos:exactMatch RHEA:35095
+property_value: skos:relatedMatch MetaCyc:PWY-7167
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28808" xsd:anyURI
created_by: sjm
creation_date: 2024-08-30T13:13:55Z
@@ -459526,6 +476047,10 @@
xref: MetaCyc:RXN-18175
xref: RHEA:51972
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.42
+property_value: skos:exactMatch KEGG_REACTION:R11646
+property_value: skos:exactMatch MetaCyc:RXN-18175
+property_value: skos:exactMatch RHEA:51972
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
created_by: sjm
creation_date: 2024-09-05T07:47:05Z
@@ -459539,6 +476064,9 @@
xref: MetaCyc:RXN-18179
xref: RHEA:52724
is_a: GO:0008146 ! sulfotransferase activity
+property_value: skos:exactMatch EC:2.8.2.38
+property_value: skos:exactMatch MetaCyc:RXN-18179
+property_value: skos:exactMatch RHEA:52724
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
created_by: sjm
creation_date: 2024-09-05T07:53:33Z
@@ -459549,7 +476077,12 @@
namespace: molecular_function
def: "Catalysis of the reactions: a 2-(omega-methylsulfanyl)alkylmalate = a 2-(omega-methylsulfanyl)alkylmaleate + H2O and a 3-(omega-methylsulfanyl)alkylmalate = a 2-(omega-methylsulfanyl)alkylmaleate + H2O." [EC:4.2.1.170]
xref: EC:4.2.1.170
+xref: RHEA:50632
+xref: RHEA:50636
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.170
+property_value: skos:narrowMatch RHEA:50632
+property_value: skos:narrowMatch RHEA:50636
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
created_by: sjm
creation_date: 2024-09-05T08:00:08Z
@@ -459564,6 +476097,10 @@
xref: MetaCyc:RXN-13433
xref: RHEA:33887
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.331
+property_value: skos:exactMatch KEGG_REACTION:R10129
+property_value: skos:exactMatch MetaCyc:RXN-13433
+property_value: skos:exactMatch RHEA:33887
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
created_by: sjm
creation_date: 2024-09-05T08:19:32Z
@@ -459593,6 +476130,7 @@
synonym: "IPPS activity" EXACT [PMID:12135472]
synonym: "isoprenyl pyrophosphate synthase activity" EXACT [PMID:12135472]
is_a: GO:0004659 ! prenyltransferase activity
+property_value: skos:broadMatch EC:2.5.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20661" xsd:anyURI
created_by: sjm
creation_date: 2024-11-22T10:52:31Z
@@ -459625,6 +476163,7 @@
synonym: "non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase activity" BROAD [EC:1.2.1.90]
xref: EC:1.2.1.90
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.2.1.90
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28144" xsd:anyURI
created_by: sjm
creation_date: 2024-11-28T16:08:56Z
@@ -459635,6 +476174,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan sulfate." [GOC:curators]
is_a: GO:0050698 ! proteoglycan sulfotransferase activity
+property_value: skos:broadMatch EC:2.8.2.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28380" xsd:anyURI
created_by: sjm
creation_date: 2024-12-02T12:14:06Z
@@ -459649,7 +476189,10 @@
xref: EC:2.5.1.n9
xref: RHEA:33495
is_a: GO:0004659 ! prenyltransferase activity
+property_value: skos:exactMatch EC:2.5.1.n9
+property_value: skos:exactMatch RHEA:33495
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29426" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2024-12-12T10:57:45Z
@@ -459662,6 +476205,7 @@
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
relationship: part_of GO:0006744 ! ubiquinone biosynthetic process
+property_value: skos:exactMatch RHEA:81215
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29459" xsd:anyURI
created_by: sjm
creation_date: 2024-12-18T09:25:15Z
@@ -459675,6 +476219,8 @@
xref: RHEA:81183
is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
relationship: part_of GO:0006744 ! ubiquinone biosynthetic process
+property_value: skos:exactMatch EC:1.14.15.46
+property_value: skos:exactMatch RHEA:81183
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29459" xsd:anyURI
created_by: sjm
creation_date: 2024-12-18T09:30:52Z
@@ -459685,10 +476231,11 @@
namespace: molecular_function
def: "Catalysis of the reaction: a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + H+ = a 2-methoxy-6-(all-trans-polyprenyl)phenol + CO2." [PMID:38295803, PMID:38425362, RHEA:81179]
xref: EC:4.1.1.130
-xref: Reactome:R-HSA-2162195 "COQ4 decarboxylates MHDB"
xref: RHEA:81179
is_a: GO:0016831 ! carboxy-lyase activity
relationship: part_of GO:0006744 ! ubiquinone biosynthetic process
+property_value: skos:exactMatch EC:4.1.1.130
+property_value: skos:exactMatch RHEA:81179
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29459" xsd:anyURI
created_by: sjm
creation_date: 2024-12-18T09:36:09Z
@@ -459726,7 +476273,9 @@
def: "Catalysis of the reaction: ethanol + NAD+ = acetaldehyde + NADH + H+." [RHEA:25290]
xref: RHEA:25290
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
+property_value: skos:exactMatch RHEA:25290
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29540" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2025-01-16T08:15:42Z
@@ -459737,7 +476286,9 @@
def: "Catalysis of a reaction that alters the macromolecular conformation of a molecule." [EC:5.6.-.-]
xref: EC:5.6.-.-
is_a: GO:0016853 ! isomerase activity
+property_value: skos:exactMatch EC:5.6.-.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29690" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2025-02-11T09:46:30Z
@@ -459748,7 +476299,9 @@
def: "Catalysis of a reaction that alters the conformation or assembly of a polypeptide." [EC:5.6.1.-]
xref: EC:5.6.1.-
is_a: GO:0120543 ! macromolecular conformation isomerase activity
+property_value: skos:exactMatch EC:5.6.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29690" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2025-02-11T09:51:11Z
@@ -459759,7 +476312,9 @@
def: "Catalysis of a reaction that alters the conformation of a nucleic acid." [EC:5.6.2.-]
xref: EC:5.6.2.-
is_a: GO:0120543 ! macromolecular conformation isomerase activity
+property_value: skos:exactMatch EC:5.6.2.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29690" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2025-02-11T09:55:25Z
@@ -459770,7 +476325,9 @@
def: "Catalysis of an oxidation-reduction (redox) reaction in which a reducing C-O-C group acts as acceptor." [EC:1.23.-.-]
xref: EC:1.23.-.-
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch EC:1.23.-.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29701" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: sjm
creation_date: 2025-02-11T18:09:07Z
@@ -459781,9 +476338,11 @@
def: "Catalysis of the reaction: Fe(II)-heme o + 2 acceptor + H2O = Fe(II)-heme a + 2 acceptor-H2. The conversion of heme o to heme a occcurs by two successive hydroxylations of the methyl group at C8 using water as the oxygen source. The first hydroxylation forms heme i, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A." [PMID:30397130, RHEA:63388]
xref: EC:1.17.99.9
xref: MetaCyc:RXN-18399
-xref: Reactome:R-HSA-2995334 "COX15 transforms heme O to heme A"
xref: RHEA:63388
is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups
+property_value: skos:exactMatch EC:1.17.99.9
+property_value: skos:exactMatch MetaCyc:RXN-18399
+property_value: skos:exactMatch RHEA:63388
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29711" xsd:anyURI
created_by: sjm
creation_date: 2025-02-13T12:39:18Z
@@ -459793,9 +476352,12 @@
name: phosphatidylinositol phospholipase C activity
namespace: molecular_function
def: "Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 1D-myo-inositol 1-phosphate + a 1,2-diacyl-sn-glycerol + H+." [RHEA:43484]
+synonym: "phosphatidylinositol phospholipase C-type activity" EXACT []
xref: RHEA:43484
-is_a: GO:0004629 ! phospholipase C activity
+is_a: GO:0004629 ! C-type glycerophospholipase activity
+property_value: skos:exactMatch RHEA:43484
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29643" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30949" xsd:anyURI
created_by: sjm
creation_date: 2025-02-21T10:31:17Z
@@ -459808,6 +476370,7 @@
xref: EC:3.2.1.196
xref: MetaCyc:RXN0-5146
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.196
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29864" xsd:anyURI
created_by: sjm
creation_date: 2025-03-06T06:46:46Z
@@ -459821,8 +476384,11 @@
synonym: "mRNA (nucleoside-2'-O-)-methyltransferase activity" RELATED [EC:2.1.1.296]
xref: EC:2.1.1.296
xref: MetaCyc:RXN-14928 {xref="skos:narrowMatch"}
+xref: RHEA:67024
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008173 ! RNA methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.296
+property_value: skos:narrowMatch RHEA:67024
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27387" xsd:anyURI
created_by: sjm
creation_date: 2025-03-20T17:49:48Z
@@ -459867,6 +476433,9 @@
xref: MetaCyc:RXN-11619
xref: RHEA:24216
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch EC:1.2.1.94
+property_value: skos:exactMatch MetaCyc:RXN-11619
+property_value: skos:exactMatch RHEA:24216
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30259" xsd:anyURI
created_by: sjm
creation_date: 2025-05-15T14:18:24Z
@@ -459879,6 +476448,8 @@
xref: MetaCyc:RXN-20408
xref: RHEA:70223
is_a: GO:0008483 ! transaminase activity
+property_value: skos:exactMatch MetaCyc:RXN-20408
+property_value: skos:exactMatch RHEA:70223
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30260" xsd:anyURI
created_by: sjm
creation_date: 2025-05-15T14:38:07Z
@@ -459890,6 +476461,7 @@
def: "Catalysis of the reaction: a ubiquinone + NADH + H+ = a ubiquinol + NAD+." [RHEA:23152]
xref: RHEA:23152
is_a: GO:0050136 ! NADH dehydrogenase (quinone) (non-electrogenic) activity
+property_value: skos:exactMatch RHEA:23152
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30272" xsd:anyURI
created_by: sjm
creation_date: 2025-05-21T13:00:47Z
@@ -459912,53 +476484,62 @@
xref: MetaCyc:RXN-11776
xref: RHEA:48128
is_a: GO:0120556 ! polyprenyl diphosphate phosphatase activity
+property_value: skos:broadMatch EC:3.6.1.68
+property_value: skos:exactMatch RHEA:48128
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30245" xsd:anyURI
created_by: sjm
creation_date: 2025-05-23T12:00:24Z
[Term]
id: GO:0120558
-name: lysophospholipase activity
+name: lysophospholipase A1 activity
namespace: molecular_function
-def: "Catalysis of the hydrolysis of a lysophospholipid (a phospholipid missing one fatty acid), removing the remaining acyl chain to yield a glycerophospho-compound and a free fatty acid." [GOC:curators]
-is_a: GO:0004620 ! phospholipase activity
-is_a: GO:0052689 ! carboxylic ester hydrolase activity
+def: "Catalysis of the hydrolysis of a lysoglycerophospholipid, removing the acyl chain at the sn-1 position to yield a glycerophospho-compound and a free fatty acid." [GOC:curators]
+is_a: GO:0140322 ! A1-type glycerophospholipase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30258" xsd:anyURI
created_by: sjm
creation_date: 2025-05-23T13:08:06Z
[Term]
id: GO:0120559
-name: phosphatidylethanolamine lysophospholipase activity
+name: phosphatidylethanolamine lysophospholipase A1 activity
namespace: molecular_function
def: "Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O = sn-glycero-3-phosphoethanolamine + a fatty acid + H+." [RHEA:32967]
+synonym: "phosphatidylethanolamine lysophospholipase A1-type activity" EXACT []
+synonym: "phosphatidylethanolamine lysophospholipase activity" BROAD []
xref: RHEA:32967
-is_a: GO:0120558 ! lysophospholipase activity
+is_a: GO:0120558 ! lysophospholipase A1 activity
+property_value: skos:exactMatch RHEA:32967
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30258" xsd:anyURI
created_by: sjm
creation_date: 2025-05-23T13:15:13Z
[Term]
id: GO:0120560
-name: phosphatidylserine lysophospholipase activity
+name: phosphatidylserine lysophospholipase A1 activity
namespace: molecular_function
def: "Catalysis of the reaction: a 1-acyl-sn-glycero-3-phospho-L-serine + H2O = sn-glycero-3-phospho-L-serine + a fatty acid + H+." [RHEA:32979]
+synonym: "phosphatidylserine lysophospholipase A1-type activity" EXACT []
synonym: "phosphatidylserine sn-1 acylhydrolase" RELATED [EC:3.1.1.111]
synonym: "phosphatidylserine-specific phospholipase A1" RELATED [EC:3.1.1.111]
xref: MetaCyc:RXN-20544
xref: RHEA:32979
-is_a: GO:0120558 ! lysophospholipase activity
+is_a: GO:0120558 ! lysophospholipase A1 activity
+property_value: skos:broadMatch EC:3.1.1.111
+property_value: skos:exactMatch RHEA:32979
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30258" xsd:anyURI
created_by: sjm
creation_date: 2025-05-23T13:15:28Z
[Term]
id: GO:0120561
-name: phosphatidylinositol lysophospholipase activity
+name: phosphatidylinositol lysophospholipase A1 activity
namespace: molecular_function
def: "Catalysis of the reaction: a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + a fatty acid + H+." [RHEA:32987]
+synonym: "phosphatidylinositol lysophospholipase A1-type activity" EXACT []
xref: RHEA:32987
-is_a: GO:0120558 ! lysophospholipase activity
+is_a: GO:0120558 ! lysophospholipase A1 activity
+property_value: skos:exactMatch RHEA:32987
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30258" xsd:anyURI
created_by: sjm
creation_date: 2025-05-23T13:15:46Z
@@ -460021,6 +476602,8 @@
xref: MetaCyc:RXN-19669
xref: RHEA:74083
is_a: GO:0004659 ! prenyltransferase activity
+property_value: skos:exactMatch RHEA:74083
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30566" xsd:anyURI
created_by: sjm
creation_date: 2025-07-14T12:21:33Z
@@ -460034,6 +476617,9 @@
xref: MetaCyc:RXN-9896
xref: RHEA:79695
is_a: GO:0016832 ! aldehyde-lyase activity
+property_value: skos:broadMatch EC:2.1.2.1
+property_value: skos:exactMatch MetaCyc:RXN-9896
+property_value: skos:exactMatch RHEA:79695
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30653" xsd:anyURI
created_by: sjm
creation_date: 2025-07-30T15:06:39Z
@@ -460049,11 +476635,34 @@
xref: RHEA:49612
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
is_a: GO:0051990 ! (R)-2-hydroxyglutarate dehydrogenase activity
+property_value: skos:exactMatch EC:1.1.1.399
+property_value: skos:exactMatch MetaCyc:KETOGLUTREDUCT-RXN
+property_value: skos:exactMatch RHEA:49612
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30833" xsd:anyURI
created_by: sjm
creation_date: 2025-09-11T11:32:12Z
[Term]
+id: GO:0120569
+name: phospholipase activity
+namespace: molecular_function
+def: "Catalysis of the hydrolysis of a phospholipid." [PMID:30109646]
+is_a: GO:0016298 ! lipase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31030" xsd:anyURI
+created_by: sjm
+creation_date: 2025-11-21T11:27:46Z
+
+[Term]
+id: GO:0120570
+name: sphingophospholipase activity
+namespace: molecular_function
+def: "Catalysis of the hydrolysis of a sphingophospholipid." [GOC:curators]
+is_a: GO:0120569 ! phospholipase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31030" xsd:anyURI
+created_by: sjm
+creation_date: 2025-11-21T11:32:06Z
+
+[Term]
id: GO:0140001
name: morula formation
namespace: biological_process
@@ -460790,6 +477399,8 @@
synonym: "protein crotonyltransferase activity" RELATED []
xref: RHEA:53908
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch RHEA:53908
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2017-07-20T16:40:57Z
@@ -460801,6 +477412,8 @@
synonym: "protein butyryltransferase activity" RELATED []
xref: RHEA:53912
is_a: GO:0016410 ! N-acyltransferase activity
+property_value: skos:exactMatch RHEA:53912
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2017-07-20T16:46:49Z
@@ -460831,6 +477444,7 @@
def: "Catalysis of the reaction: crotonyl-CoA + histone = CoA + crotonyl-histone." [PMID:25818647]
is_a: GO:0140064 ! peptide crotonyltransferase activity
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:broadMatch RHEA:53908
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pg
creation_date: 2017-07-20T16:55:16Z
@@ -460842,6 +477456,7 @@
def: "Catalysis of the reaction: butyryl-CoA + histone = CoA + butyryl-histone." [PMID:27105113]
is_a: GO:0140065 ! peptide butyryltransferase activity
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:broadMatch RHEA:53912
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pg
creation_date: 2017-07-20T16:56:33Z
@@ -460959,8 +477574,11 @@
xref: Wikipedia:AP_endonuclease
is_a: GO:0003906 ! DNA-(apurinic or apyrimidinic site) endonuclease activity
is_a: GO:0016835 ! carbon-oxygen lyase activity
+property_value: skos:exactMatch EC:4.2.99.18
+property_value: skos:exactMatch RHEA:66592
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22262" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27071" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2017-07-24T11:33:34Z
@@ -461031,6 +477649,7 @@
def: "Catalysis of the reaction: acetyl-CoA + a L-amino acid = CoA + an N-acetyl-L-amino-acid. In some cases acetyl phosphate can be used as a donor." [GOC:pg, RHEA:83863]
xref: RHEA:83863
is_a: GO:0008080 ! N-acetyltransferase activity
+property_value: skos:exactMatch RHEA:83863
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29604" xsd:anyURI
created_by: pg
creation_date: 2025-01-24T10:40:36Z
@@ -461052,7 +477671,9 @@
def: "Catalysis of the reaction: acetaldehyde + NAD+ + H2O = acetate + NADH + 2 H+." [PMID:9473035, RHEA:25294]
xref: RHEA:25294
is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity
+property_value: skos:exactMatch RHEA:25294
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29544" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2025-01-28T07:26:40Z
@@ -461063,7 +477684,9 @@
def: "Catalysis of the reaction: acetaldehyde + NADP+ + H2O = acetate + NADPH + 2 H+." [PMID:15659684, PMID:9473035, RHEA:25298]
xref: RHEA:25298
is_a: GO:0033721 ! aldehyde dehydrogenase (NADP+) activity
+property_value: skos:exactMatch RHEA:25298
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29544" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2025-01-28T07:28:10Z
@@ -461202,6 +477825,7 @@
synonym: "murein lytic endotransglycosylase E activity" NARROW []
xref: EC:4.2.2.n1
is_a: GO:0008933 ! peptidoglycan lytic transglycosylase activity
+property_value: skos:exactMatch EC:4.2.2.n1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21167" xsd:anyURI
created_by: pg
creation_date: 2025-02-05T12:50:17Z
@@ -461250,23 +477874,10 @@
subset: goslim_prokaryote
subset: goslim_prokaryote_ribbon
xref: Reactome:R-HSA-1449687 "Corticosteroids bind to CBG in blood"
-xref: Reactome:R-HSA-196126 "STAR mediates CHOL translocation from cytosol to mitochondrial intermembrane space"
-xref: Reactome:R-HSA-209738 "VD3 binds GC"
-xref: Reactome:R-HSA-209944 "25(OH)D binds GC"
-xref: Reactome:R-HSA-2395764 "atREs binds to nascent CM"
-xref: Reactome:R-HSA-2399913 "atRAL binds to RBP2"
-xref: Reactome:R-HSA-2404142 "atROL binds RBP1"
-xref: Reactome:R-HSA-2855259 "atROL binds RBP1 (parenchymal cell)"
xref: Reactome:R-HSA-3149494 "MMACHC:cob(II)alamin binds MMADHC"
xref: Reactome:R-HSA-3149563 "MMADHC targets transport of cytosolic cob(II)alamin to mitochondria"
xref: Reactome:R-HSA-3159259 "MMAA:MUT binds AdoCbl"
xref: Reactome:R-HSA-3204318 "cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR"
-xref: Reactome:R-HSA-5246478 "APOM binds retinoids"
-xref: Reactome:R-HSA-8870499 "PLEKHA3,8 bind PI4P, ARF1"
-xref: Reactome:R-HSA-8932980 "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane"
-xref: Reactome:R-HSA-8963851 "VD3 dissociates from GC"
-xref: Reactome:R-HSA-9661432 "BIL binds ALB"
-xref: Reactome:R-HSA-9663511 "BIL binds GSTA1, FABP1"
is_a: GO:0003674 ! molecular_function
relationship: has_part GO:0005488 ! binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14221" xsd:anyURI
@@ -461868,7 +478479,7 @@
name: chicken-wire-like collagen network
namespace: cellular_component
def: "Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane." [PMID:21421911, PMID:21421915, PMID:31387942]
-is_a: GO:0098645 ! collagen network
+is_a: GO:0098645 ! complex of network-forming collagens
relationship: part_of GO:0140143 ! collagenous component of basement membrane
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29401" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30149" xsd:anyURI
@@ -461880,7 +478491,7 @@
name: hexagonal collagen network of basement membrane
namespace: cellular_component
def: "Supramolecular structure formed by trimers of collagen VIII and found in the basement membrane." [PMID:21421911, PMID:2376131, PMID:3047147, PMID:31387942]
-is_a: GO:0098645 ! collagen network
+is_a: GO:0098645 ! complex of network-forming collagens
relationship: part_of GO:0140143 ! collagenous component of basement membrane
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29402" xsd:anyURI
created_by: pg
@@ -462030,8 +478641,18 @@
namespace: molecular_function
def: "Catalysis of the reaction: a 3alpha-hydroxysteroid + NAD(P)+ = a 3-oxosteroid + NAD(P)H + H+." [EC:1.1.1.357]
comment: Note that EC distinguishes stereospecific reactions: EC:1.1.1.213 and EC:1.1.1.50. These are out of scope for GO.
+xref: EC:1.1.1.213
xref: EC:1.1.1.357
+xref: EC:1.1.1.50
+xref: RHEA:34779
+xref: RHEA:34783
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch MetaCyc:1.1.1.209-RXN
+property_value: skos:exactMatch EC:1.1.1.357
+property_value: skos:narrowMatch EC:1.1.1.213
+property_value: skos:narrowMatch EC:1.1.1.50
+property_value: skos:narrowMatch RHEA:34779
+property_value: skos:narrowMatch RHEA:34783
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29921" xsd:anyURI
created_by: pg
creation_date: 2025-04-09T15:19:24Z
@@ -462043,6 +478664,7 @@
def: "Catalysis of the reaction: (R)-lactate + FAD + H+ = FADH2 + pyruvate." [RHEA:82479]
xref: RHEA:82479
is_a: GO:0047809 ! D-lactate dehydrogenase activity
+property_value: skos:exactMatch RHEA:82479
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30132" xsd:anyURI
created_by: pg
creation_date: 2025-04-17T08:20:22Z
@@ -462091,6 +478713,7 @@
def: "Catalysis of the activity: a (2R)-2-hydroxycarboxylate + FAD + H+ = a 2-oxocarboxylate + FADH2." [PMID:37863926, RHEA:82511]
xref: RHEA:82511
is_a: GO:0033719 ! (2R)-oxo-acid reductase activity
+property_value: skos:exactMatch RHEA:82511
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30138" xsd:anyURI
created_by: pg
creation_date: 2025-05-20T06:45:42Z
@@ -462101,8 +478724,12 @@
namespace: molecular_function
def: "Catalysis of the reaction: a (2R)-2-hydroxycarboxylate + NAD+ = a 2-oxocarboxylate + NADH + H+." [RHEA:35643]
xref: EC:1.1.1.345
+xref: RHEA:10052
xref: RHEA:35643
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.345
+property_value: skos:exactMatch RHEA:35643
+property_value: skos:narrowMatch RHEA:10052
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30138" xsd:anyURI
created_by: pg
creation_date: 2025-05-20T08:52:20Z
@@ -462114,7 +478741,6 @@
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. In most organisms, this pathway links glycolysis to the TCA cycle, by a series of three reactions carried out by a multisubunit complex called the 'pyruvate dehydrogenase complex', even though pyruvate dehydrogenase activity describes only one of those reactions." [PMID:15855260]
is_a: GO:0009891 ! positive regulation of biosynthetic process
is_a: GO:0010510 ! regulation of pyruvate decarboxylation to acetyl-CoA
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0045937 ! positive regulation of phosphate metabolic process
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
@@ -462235,6 +478861,8 @@
xref: RHEA:53916
is_a: GO:0016410 ! N-acyltransferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch RHEA:53916
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2025-07-22T09:31:41Z
@@ -462244,6 +478872,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: acetyl-CoA + histone H1-4 L-lysine (position 34) = CoA + histone H1-4 N6-acetyl-L-lysine (position 34)." [PMID:22465951]
is_a: GO:0160262 ! histone H1 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30567" xsd:anyURI
created_by: pg
creation_date: 2025-07-22T09:54:23Z
@@ -462342,15 +478971,13 @@
[Term]
id: GO:0140196
-name: positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
+name: obsolete positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph]
-is_a: GO:0051240 ! positive regulation of multicellular organismal process
-is_a: GO:0071879 ! positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway
-is_a: GO:0106071 ! positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0086023 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
-relationship: positively_regulates GO:0086023 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0106071
created_by: pg
creation_date: 2018-02-15T19:13:29Z
@@ -462378,14 +479005,14 @@
[Term]
id: GO:0140199
-name: negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
+name: obsolete negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph]
-is_a: GO:0051241 ! negative regulation of multicellular organismal process
-is_a: GO:0071878 ! negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0086023 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
-relationship: negatively_regulates GO:0086023 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003015
+consider: GO:0071878
created_by: pg
creation_date: 2018-02-15T19:31:23Z
@@ -462512,8 +479139,6 @@
name: folic acid:proton symporter activity
namespace: molecular_function
def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: folic acid(out) + H+(out) = folic acid(in) + H+(in). The main folic acid symporter is the Proton-Coupled Folate Transporter (PCFT/SLC46A1), which has similar affinity for transport of reduced folates (5-methyl THF, 5-formyl THF) and folic acid." [PMID:24745983]
-xref: Reactome:R-HSA-200646 "Cytosolic folate export across the plasma membrane"
-xref: Reactome:R-HSA-200729 "SLC46A1 transports FOLA from extracellular region to cytosol"
xref: TC:2.A.1.50.1
is_a: GO:0008517 ! folic acid transmembrane transporter activity
is_a: GO:0015295 ! solute:proton symporter activity
@@ -462611,6 +479236,7 @@
def: "Catalysis of the reaction: 2-methylpropenoyl-CoA + L-lysyl-[protein] = N6-methacrylyl-L-lysyl-[protein] + CoA + H+. Methacryl-CoA is a synonym of 2-methylpropenoyl-CoA." [PMID:34961760, PMID:40339582]
synonym: "histone 2-methylpropenoyl transferase activity" EXACT []
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:broadMatch RHEA:83547
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30567" xsd:anyURI
created_by: pg
creation_date: 2025-07-22T13:00:24Z
@@ -462621,6 +479247,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: N6-methacrylyl-L-lysyl-[histone] + H2O = 2-methylprop-2-enoate + L-lysyl-[histone]." [PMID:34961760]
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:broadMatch RHEA:83551
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30567" xsd:anyURI
created_by: pg
creation_date: 2025-07-22T13:14:18Z
@@ -462737,6 +479364,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: N(6)-benzoyl-L-lysyl-[protein] + NAD+ + H2O = 2''-O-benzoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]." [PMID:34961760]
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:broadMatch RHEA:83535
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30567" xsd:anyURI
created_by: pg
creation_date: 2025-07-22T13:37:04Z
@@ -462747,6 +479375,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: N(6)-isonicotinyl-L-lysyl-[protein] + H2O = isonicotinate + L-lysyl-[protein]." [PMID:34545082]
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:broadMatch RHEA:83543
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30567" xsd:anyURI
created_by: pg
creation_date: 2025-07-22T13:38:30Z
@@ -462757,6 +479386,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: isonicotinyl-CoA + histone = coA + N(6)-isonicotinyl-histone." [PMID:34545082]
is_a: GO:0140993 ! histone modifying activity
+property_value: skos:broadMatch RHEA:83539
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30567" xsd:anyURI
created_by: pg
creation_date: 2025-07-22T13:41:06Z
@@ -462775,29 +479405,28 @@
[Term]
id: GO:0140232
-name: intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential
+name: obsolete intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential
namespace: molecular_function
-def: "Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the presynaptic membrane potential." [PMID:21358644]
-comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
-subset: goslim_synapse
+def: "OBSOLETE. Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the presynaptic membrane potential." [PMID:21358644]
+comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
synonym: "intracellular cAMP activated cation channel activity involved in regulation of presynaptic membrane potential" EXACT []
-is_a: GO:0005222 ! intracellularly cAMP-activated cation channel activity
-relationship: part_of GO:0060078 ! regulation of postsynaptic membrane potential
-property_value: term_tracker_item "https://github.com/geneontology/synapse/issues/231" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31205" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0005222
created_by: pg
creation_date: 2018-07-09T11:30:40Z
[Term]
id: GO:0140233
-name: intracellular cAMP-activated cation channel activity involved in regulation of postsynaptic membrane potential
+name: obsolete intracellular cAMP-activated cation channel activity involved in regulation of postsynaptic membrane potential
namespace: molecular_function
-def: "Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the postsynaptic membrane potential." [GOC:pvn]
-comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
-subset: goslim_synapse
+def: "OBSOLETE. Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the postsynaptic membrane potential." [GOC:pvn]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "intracellular cAMP activated cation channel activity involved in regulation of postsynaptic membrane potential" EXACT []
-is_a: GO:0005222 ! intracellularly cAMP-activated cation channel activity
-relationship: part_of GO:0060078 ! regulation of postsynaptic membrane potential
-property_value: term_tracker_item "https://github.com/geneontology/synapse/issues/231" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31205" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0005222
created_by: pg
creation_date: 2018-07-09T11:31:18Z
@@ -463267,6 +479896,7 @@
name: arthro-series glucosylceramide biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of arthro-series glucosylceramides that begins with the synthesis of a tetrasaccharide core GalNAc-beta-1,4-GlcNAc-beta-1,3-Man-beta-1,4Glc-ceramide. This core can be further elongated with the sequential addition of various carbohydrate units." [PMID:35536927]
+xref: MetaCyc:PWY-8612
is_a: GO:0006688 ! glycosphingolipid biosynthetic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30616" xsd:anyURI
created_by: pg
@@ -463475,7 +480105,10 @@
xref: EC:6.3.5.13
xref: RHEA:57928
is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor
+property_value: skos:exactMatch EC:6.3.5.13
+property_value: skos:exactMatch RHEA:57928
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16422" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2018-10-08T19:12:57Z
@@ -463527,6 +480160,8 @@
xref: MetaCyc:1.7.99.8-RXN
xref: RHEA:23232
is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.7.2.8
+property_value: skos:exactMatch RHEA:23232
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30814" xsd:anyURI
created_by: pg
creation_date: 2025-09-09T14:28:09Z
@@ -463578,6 +480213,7 @@
xref: RHEA:58256
is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch RHEA:58256
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28476" xsd:anyURI
created_by: pg
creation_date: 2018-11-22T14:35:39Z
@@ -463667,7 +480303,6 @@
synonym: "small molecular sensor activity" EXACT []
synonym: "small molecule sensing activity" EXACT []
synonym: "small molecule sensor activity" NARROW []
-xref: Reactome:R-HSA-9854368 "ROS,RNS oxidize ACO2:4Fe-4S"
is_a: GO:0098772 ! molecular function regulator activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28772" xsd:anyURI
created_by: pg
@@ -463726,6 +480361,8 @@
xref: MetaCyc:RXN-11175
xref: RHEA:49816
is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.7.2.7
+property_value: skos:exactMatch RHEA:49816
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30814" xsd:anyURI
created_by: pg
creation_date: 2025-09-09T14:34:43Z
@@ -463739,6 +480376,8 @@
xref: MetaCyc:HAONITRO-RXN
xref: RHEA:45032
is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor
+property_value: skos:exactMatch EC:1.7.2.6
+property_value: skos:exactMatch RHEA:45032
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30814" xsd:anyURI
created_by: pg
creation_date: 2025-09-09T14:44:04Z
@@ -463754,11 +480393,58 @@
creation_date: 2019-03-22T14:25:43Z
[Term]
+id: GO:0140307
+name: phospholipase C-activating N-formyl peptide-activated signaling pathway
+namespace: biological_process
+def: "A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by an N-formyl peptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. chemotaxis. N-formyl peptides include N-formylmethionyl-leucyl-phenylalanine (fMLF, fMLP or N-formyl-met-leu-phe), an N-formylated tripeptide sometimes simply referred to as chemotactic peptide. fMLF is a potent polymorphonuclear leukocyte (PMN) chemotactic factor and is also a macrophage activator." [PMID:10466071, PMID:22728827, PMID:23994464]
+synonym: "fMLP-activated G protein-coupled receptor signaling pathway" NARROW []
+is_a: GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27490" xsd:anyURI
+created_by: pg
+creation_date: 2025-10-20T14:16:02Z
+
+[Term]
+id: GO:0140308
+name: insulin-like growth factor binding receptor complex
+namespace: cellular_component
+def: "A plasma membrane-localized protein complex that binds insulin-like growth factors (IGF1 or IGF2). This class includes both signaling receptor complexes, such as the insulin-like growth factor 1 receptor (IGF1R) complex, which possesses intrinsic tyrosine kinase activity and initiates intracellular signaling cascades upon ligand binding, and non-signaling receptor complexes such as the insulin-like growth factor 2 receptor (IGF2R), which functions to sequester IGF2 and regulate its bioavailability by directing it to lysosomal degradation. These complexes regulate cell growth, proliferation, survival, and development by modulating IGF signaling." [PMID:17475626, PMID:27140600, PMID:31594955, PMID:35749888]
+synonym: "IGF-binding receptor complex" EXACT []
+is_a: GO:0098802 ! plasma membrane signaling receptor complex
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30922" xsd:anyURI
+created_by: pg
+creation_date: 2025-10-20T15:19:56Z
+
+[Term]
+id: GO:0140309
+name: unfolded protein carrier activity
+namespace: molecular_function
+def: "A protein carrier activity that binds to a protein in an unfolded state and escorts it between two different cellular components. The unfolded protein carrier prevents aggregation of the target protein." [PMID:39488384]
+synonym: "holdase" BROAD []
+synonym: "holdase-carrier chaperone" EXACT []
+is_a: GO:0140597 ! protein carrier chaperone
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30552" xsd:anyURI
+created_by: pg
+creation_date: 2025-11-03T13:14:32Z
+
+[Term]
+id: GO:0140310
+name: positive regulation of peptidoglycan biosynthetic process
+namespace: biological_process
+def: "Any process that increases the rate, frequency, or extent of peptidoglycan biosynthetic process." [PMID:37688380]
+is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process
+is_a: GO:0010981 ! regulation of cell wall macromolecule metabolic process
+intersection_of: GO:0065007 ! biological regulation
+intersection_of: positively_regulates GO:0009252 ! peptidoglycan biosynthetic process
+relationship: positively_regulates GO:0009252 ! peptidoglycan biosynthetic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30927" xsd:anyURI
+created_by: pg
+creation_date: 2025-11-04T10:19:39Z
+
+[Term]
id: GO:0140311
name: protein sequestering activity
namespace: molecular_function
def: "Binding to a protein to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active." [PMID:1493333]
-xref: Reactome:R-HSA-1678694 "Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans"
is_a: GO:0140313 ! molecular sequestering activity
intersection_of: GO:0140313 ! molecular sequestering activity
intersection_of: has_part GO:0005515 ! protein binding
@@ -463796,7 +480482,6 @@
subset: goslim_prokaryote_ribbon
xref: Reactome:R-HSA-203553 "eNOS binds NOSIP"
xref: Reactome:R-HSA-203680 "eNOS:NOSIP translocation from caveolae to intracellular compartments"
-xref: Reactome:R-HSA-2404134 "RBP4:atROL binds TTR"
xref: Reactome:R-HSA-3245898 "TCN1 binds correnoids in the circulation"
is_a: GO:0003674 ! molecular_function
created_by: pg
@@ -463899,6 +480584,20 @@
creation_date: 2019-04-03T09:21:48Z
[Term]
+id: GO:0140322
+name: A1-type glycerophospholipase activity
+namespace: molecular_function
+def: "A glycerophospholipase activity that cleaves the fatty acid attached to the sn-1 position of the glycerol group of a glycerophospholipid." [PMID:30109646]
+is_a: GO:0004620 ! glycerophospholipase activity
+is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30258" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31049" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31078" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31198" xsd:anyURI
+created_by: pg
+creation_date: 2025-11-07T09:02:05Z
+
+[Term]
id: GO:0140323
name: obsolete solute:monoatomic anion antiporter activity
namespace: molecular_function
@@ -463912,6 +480611,16 @@
creation_date: 2019-04-03T16:23:14Z
[Term]
+id: GO:0140324
+name: lysophospholipase C activity
+namespace: molecular_function
+def: "Hydrolysis of a lysoglycerophospholipid at the first phosphodiester bond between the phosphate and glycerol." [PMID:32917725]
+is_a: GO:0004629 ! C-type glycerophospholipase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30949" xsd:anyURI
+created_by: pg
+creation_date: 2025-11-10T12:35:51Z
+
+[Term]
id: GO:0140325
name: negative regulation of protein localization to medial cortex
namespace: biological_process
@@ -463945,9 +480654,12 @@
xref: Reactome:R-HSA-947591 "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane"
is_a: GO:0140303 ! intramembrane lipid transporter activity
is_a: GO:0140657 ! ATP-dependent activity
+property_value: skos:broadMatch RHEA:66132
+property_value: skos:exactMatch EC:7.6.2.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17648" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21612" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28937" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2019-04-29T12:42:26Z
@@ -463959,6 +480671,7 @@
comment: Nomenclature note. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. The direction of the translocation should be taken into account for annotation (from the exoplasmic to the cytosolic leaflet of a membrane).
synonym: "flippase activity (exoplasmic to cytosolic leaflet)" EXACT []
is_a: GO:0140326 ! ATPase-coupled intramembrane lipid transporter activity
+property_value: skos:broadMatch RHEA:66132
created_by: pg
creation_date: 2019-04-29T12:51:21Z
@@ -463970,6 +480683,7 @@
comment: Nomenclature note. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. The direction of the translocation should be taken into account for annotation (from the cytosolic to the exoplasmic leaflet of a membrane).
synonym: "floppase activity (cytosolic to exoplasmic leaflet)" EXACT []
is_a: GO:0140326 ! ATPase-coupled intramembrane lipid transporter activity
+property_value: skos:broadMatch RHEA:66132
created_by: pg
creation_date: 2019-04-29T12:58:53Z
@@ -464026,6 +480740,7 @@
synonym: "glycerophospholipid flippase activity (exoplasmic to cytosolic leaflet)" EXACT []
is_a: GO:0005548 ! phospholipid transporter activity
is_a: GO:0140327 ! flippase activity
+property_value: skos:broadMatch RHEA:66132
created_by: pg
creation_date: 2019-05-13T11:14:56Z
@@ -464041,6 +480756,35 @@
creation_date: 2019-05-13T12:23:36Z
[Term]
+id: GO:0140335
+name: GPI anchor phospholipase C activity
+namespace: molecular_function
+def: "Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol, by cleavage of the first phosphodiester bond between the phosphate and glycerol." [PMID:23329048]
+synonym: "glycoprotein phospholipase C activity" EXACT []
+synonym: "glycosylphosphatidyl inositol-anchor protein phospholipase C activity" EXACT []
+synonym: "GPI-PLC activity" EXACT []
+is_a: GO:0004629 ! C-type glycerophospholipase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28868" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31078" xsd:anyURI
+created_by: pg
+creation_date: 2025-11-11T08:44:01Z
+
+[Term]
+id: GO:0140336
+name: glycosylphosphatidylinositol phospholipase D activity
+namespace: molecular_function
+def: "Catalysis of the reaction: a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + H2O = 6-(alpha-D-glucosaminyl)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphate + H+." [RHEA:10832]
+synonym: "GPI phospholipase D activity" EXACT []
+synonym: "phosphatidylinositol phospholipase D activity" BROAD []
+xref: RHEA:10832
+is_a: GO:0004630 ! D-type glycerophospholipase activity
+property_value: skos:broadMatch EC:3.1.4.50
+property_value: skos:exactMatch RHEA:10832
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28868" xsd:anyURI
+created_by: pg
+creation_date: 2025-11-11T15:59:09Z
+
+[Term]
id: GO:0140337
name: diacylglyceride transfer activity
namespace: molecular_function
@@ -464092,10 +480836,21 @@
synonym: "phosphatidylethanolamine floppase activity (cytosolic to exoplasmic leaflet)" EXACT []
is_a: GO:0005548 ! phospholipid transporter activity
is_a: GO:0140328 ! floppase activity
+property_value: skos:broadMatch RHEA:66132
created_by: pg
creation_date: 2019-05-16T11:40:45Z
[Term]
+id: GO:0140342
+name: venom-mediated perturbation of heart contraction
+namespace: biological_process
+def: "A process in which an organism alters or subverts the heart contractility in another organism via the action of a venom." [PMID:38167790]
+is_a: GO:0140134 ! venom-mediated perturbation of blood circulation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31096" xsd:anyURI
+created_by: pg
+creation_date: 2025-11-20T10:56:34Z
+
+[Term]
id: GO:0140343
name: phosphatidylserine transfer activity
namespace: molecular_function
@@ -464123,6 +480878,7 @@
synonym: "phosphatidylcholine flippase activity (exoplasmic to cytosolic leaflet)" EXACT []
is_a: GO:0008525 ! phosphatidylcholine transporter activity
is_a: GO:0140333 ! glycerophospholipid flippase activity
+property_value: skos:broadMatch RHEA:66132
created_by: pg
creation_date: 2019-05-16T13:43:47Z
@@ -464134,6 +480890,7 @@
synonym: "phosphatidylserine flippase activity (exoplasmic to cytosolic leaflet)" EXACT []
is_a: GO:0015247 ! aminophospholipid flippase activity
is_a: GO:0140333 ! glycerophospholipid flippase activity
+property_value: skos:broadMatch RHEA:66132
created_by: pg
creation_date: 2019-05-16T13:44:23Z
@@ -464144,6 +480901,7 @@
def: "Catalysis of the movement of N-retinylidene-N-retinylphosphatidylethanolamine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP." [PMID:10412977]
synonym: "N-retinylidene-phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaflet)" EXACT []
is_a: GO:0140333 ! glycerophospholipid flippase activity
+property_value: skos:broadMatch RHEA:66132
created_by: pg
creation_date: 2019-05-16T13:44:51Z
@@ -464154,10 +480912,32 @@
def: "Catalysis of the movement of lysophosphatidylcholine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP." [PMID:26945070]
synonym: "lysophosphatidylcholine flippase activity (exoplasmic to cytosolic leaflet)" EXACT []
is_a: GO:0140333 ! glycerophospholipid flippase activity
+property_value: skos:broadMatch RHEA:66132
created_by: pg
creation_date: 2019-05-16T13:45:17Z
[Term]
+id: GO:0140349
+name: laminin network
+namespace: cellular_component
+def: "A supramolecular network that forms mainly through linkages of the short laminin arms between the N-terminal regions of one alpha, one beta, and one gamma chain. The laminin network associates with the collagen network to create the stable, sheet-like structure of the basement membrane ECM." [PMID:1577869, PMID:21421915, PMID:23263632, PMID:28187500]
+synonym: "laminin complex" BROAD []
+is_a: GO:0099080 ! supramolecular complex
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31053" xsd:anyURI
+created_by: pg
+creation_date: 2025-12-01T12:38:57Z
+
+[Term]
+id: GO:0140350
+name: inchworm-type cell migration
+namespace: biological_process
+def: "A type of amoeboid cell migration involving minimal contact between the cell and the surface, with the cell body standing upright and twisting, followed by rapid reattachment for directed movement." [PMID:40712579]
+is_a: GO:0001667 ! ameboidal-type cell migration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31169" xsd:anyURI
+created_by: pg
+creation_date: 2025-12-09T15:04:11Z
+
+[Term]
id: GO:0140351
name: glycosylceramide flippase activity
namespace: molecular_function
@@ -464169,6 +480949,7 @@
synonym: "glycosylceramide flippase activity (exoplasmic to cytosolic leaflet)" EXACT []
is_a: GO:0046624 ! sphingolipid transporter activity
is_a: GO:0140327 ! flippase activity
+property_value: skos:broadMatch RHEA:66132
created_by: pg
creation_date: 2019-05-20T13:29:48Z
@@ -464219,6 +481000,22 @@
creation_date: 2019-05-27T09:56:50Z
[Term]
+id: GO:0140356
+name: L-lyxonate dehydratase activity
+namespace: molecular_function
+def: "Catalysis of the reaction: L-lyxonate =2-dehydro-3-deoxy-L-arabinonate + H2O." [RHEA:62436]
+xref: EC:4.2.1.176
+xref: MetaCyc:RXN-15590
+xref: RHEA:62436
+is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.176
+property_value: skos:exactMatch MetaCyc:RXN-15590
+property_value: skos:exactMatch RHEA:62436
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31257" xsd:anyURI
+created_by: pg
+creation_date: 2025-12-23T12:45:43Z
+
+[Term]
id: GO:0140357
name: heme export from vacuole to cytoplasm
namespace: biological_process
@@ -464414,7 +481211,8 @@
id: GO:0140380
name: psilocybin biosynthetic process
namespace: biological_process
-def: "The chemical reactions and pathways resulting in the formation of psilocybin, a psychotropic tryptamine-derived natural product." [PMID:28763571]
+def: "The chemical reactions and pathways resulting in the formation of psilocybin, a psychotropic tryptamine-derived natural product." [MetaCyc:PWY-7936, PMID:28763571]
+xref: MetaCyc:PWY-7936
is_a: GO:0006568 ! L-tryptophan metabolic process
is_a: GO:0006796 ! phosphate-containing compound metabolic process
is_a: GO:0035835 ! indole alkaloid biosynthetic process
@@ -464425,7 +481223,9 @@
relationship: has_part GO:0140381 ! 4-hydroxytryptamine 4-phosphate methyltransferase activity
relationship: has_part GO:0140382 ! tryptamine 4-monooxygenase activity
relationship: has_part GO:0140383 ! 4-hydroxytryptamine kinase activity
+property_value: skos:exactMatch MetaCyc:PWY-7936
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23954" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31028" xsd:anyURI
created_by: pg
creation_date: 2019-11-20T10:03:05Z
@@ -464439,6 +481239,9 @@
xref: EC:2.1.1.345
xref: RHEA:55568
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.345
+property_value: skos:exactMatch RHEA:55568
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2019-11-20T10:16:28Z
@@ -464450,6 +481253,9 @@
xref: EC:1.14.99.59
xref: RHEA:15865
is_a: GO:0004497 ! monooxygenase activity
+property_value: skos:exactMatch EC:1.14.99.59
+property_value: skos:exactMatch RHEA:15865
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2019-11-20T10:26:21Z
@@ -464461,6 +481267,9 @@
xref: EC:2.7.1.222
xref: RHEA:55564
is_a: GO:0016301 ! kinase activity
+property_value: skos:exactMatch EC:2.7.1.222
+property_value: skos:exactMatch RHEA:55564
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2019-11-20T10:30:05Z
@@ -464483,6 +481292,9 @@
xref: MetaCyc:RXN-9480
xref: RHEA:35447
is_a: GO:0045703 ! ketoreductase activity
+property_value: skos:exactMatch EC:1.1.1.349
+property_value: skos:exactMatch RHEA:35447
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2019-11-28T14:38:12Z
@@ -464496,6 +481308,8 @@
xref: RHEA:33503
is_a: GO:0140359 ! ABC-type transporter activity
is_a: GO:1901474 ! azole transmembrane transporter activity
+property_value: skos:exactMatch RHEA:33503
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2019-11-28T18:29:48Z
@@ -464509,6 +481323,9 @@
xref: RHEA:35575
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
relationship: part_of GO:0045122 ! aflatoxin biosynthetic process
+property_value: skos:exactMatch EC:1.14.14.116
+property_value: skos:exactMatch RHEA:35575
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2019-11-29T08:48:23Z
@@ -464520,6 +481337,9 @@
xref: EC:1.1.1.352
xref: RHEA:35475
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.352
+property_value: skos:exactMatch RHEA:35475
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2019-11-29T08:56:49Z
@@ -464529,7 +481349,16 @@
namespace: molecular_function
def: "Catalyzes the reactions: versiconal hemiacetal acetate + H2O = versiconal + acetate, as well as versiconol acetate + H2O = versiconol + acetate." [EC:3.1.1.94, PMID:15006741, PMID:15932995, PMID:8368837]
xref: EC:3.1.1.94
+xref: MetaCyc:RXN-9488
+xref: MetaCyc:RXN-9493
+xref: RHEA:35715
+xref: RHEA:35719
is_a: GO:0016788 ! hydrolase activity, acting on ester bonds
+property_value: skos:exactMatch EC:3.1.1.94
+property_value: skos:narrowMatch MetaCyc:RXN-9488
+property_value: skos:narrowMatch MetaCyc:RXN-9493
+property_value: skos:narrowMatch RHEA:35715
+property_value: skos:narrowMatch RHEA:35719
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
created_by: pg
creation_date: 2019-11-29T10:14:17Z
@@ -464544,6 +481373,9 @@
xref: MetaCyc:RXN-9495
xref: RHEA:35743
is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
+property_value: skos:exactMatch EC:1.14.19.n5
+property_value: skos:exactMatch RHEA:35743
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2019-11-29T10:30:25Z
@@ -464553,8 +481385,17 @@
namespace: molecular_function
def: "Catalyzes the reaction: 8-O-methylsterigmatocystin + 2 [reduced NADPH--hemoprotein reductase] + 2 O2 = aflatoxin B + 2 [oxidized NADPH--hemoprotein reductase] + H2O + methanol + CO2. Produces both aflatoxin B(1) and aflatoxin B(2)." [EC:1.14.14.117]
xref: EC:1.14.14.117
+xref: MetaCyc:RXN-9497
+xref: MetaCyc:RXN-9502
+xref: RHEA:35759
+xref: RHEA:35763
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
relationship: part_of GO:0045122 ! aflatoxin biosynthetic process
+property_value: skos:exactMatch EC:1.14.14.117
+property_value: skos:narrowMatch MetaCyc:RXN-9497
+property_value: skos:narrowMatch MetaCyc:RXN-9502
+property_value: skos:narrowMatch RHEA:35759
+property_value: skos:narrowMatch RHEA:35763
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
created_by: pg
creation_date: 2019-11-29T11:06:07Z
@@ -464943,7 +481784,9 @@
def: "Catalysis of the transfer of a stearoyl (systematic name, octadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: octadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-octadecanoyl-L-cysteinyl-[protein]." [PMID:12681491, PMID:22247542, PMID:22968831, RHEA:59740]
xref: RHEA:59740
is_a: GO:0019707 ! protein-cysteine S-acyltransferase activity
+property_value: skos:exactMatch RHEA:59740
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18882" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2020-03-11T09:55:48Z
@@ -464954,7 +481797,9 @@
def: "Catalysis of the transfer of an oleoyl (systematic name, (9Z)-octadecenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: (9Z)-octadecenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(9Z-octadecenoyl)-L-cysteinyl-[protein]." [PMID:22247542, RHEA:59744]
xref: RHEA:59744
is_a: GO:0019707 ! protein-cysteine S-acyltransferase activity
+property_value: skos:exactMatch RHEA:59744
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18882" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2020-03-11T09:56:11Z
@@ -464965,7 +481810,9 @@
def: "Catalysis of the transfer of an arachidonoyl (systematic name, (5Z,8Z,11Z,14Z)-eicosatetraenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: in the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-cysteinyl-[protein]." [PMID:12681491, PMID:22247542, PMID:22968831, RHEA:59748]
xref: RHEA:59748
is_a: GO:0019707 ! protein-cysteine S-acyltransferase activity
+property_value: skos:exactMatch RHEA:59748
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18882" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2020-03-11T09:56:24Z
@@ -466150,7 +482997,10 @@
xref: EC:2.4.2.62
xref: RHEA:22820
is_a: GO:0035252 ! UDP-xylosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.62
+property_value: skos:exactMatch RHEA:22820
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16869" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2020-11-25T13:45:18Z
@@ -466162,7 +483012,10 @@
xref: EC:2.4.1.376
xref: RHEA:58116
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:exactMatch EC:2.4.1.376
+property_value: skos:exactMatch RHEA:58116
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16869" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2020-11-25T14:19:23Z
@@ -466174,7 +483027,10 @@
xref: EC:2.4.2.63
xref: RHEA:62016
is_a: GO:0035252 ! UDP-xylosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.63
+property_value: skos:exactMatch RHEA:62016
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16869" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2020-11-25T14:30:56Z
@@ -466186,7 +483042,10 @@
xref: EC:2.4.2.42
xref: RHEA:56064
is_a: GO:0035252 ! UDP-xylosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.42
+property_value: skos:exactMatch RHEA:56064
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/16869" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2020-11-25T16:07:58Z
@@ -466211,8 +483070,10 @@
namespace: molecular_function
def: "The activity of removing a protein from a membrane, by binding to a transmembrane helical fragment of a tail-anchored protein and releasing it from the the hydrophobic region of one or both lipid bilayers. The reaction is driven by ATP hydrolysis." [PMID:24821790, PMID:28712723, PMID:32973005]
synonym: "transmembrane helix dislocase\ntransmembrane protein dislocase activity" RELATED []
+xref: RHEA:66168
is_a: GO:0140318 ! protein transporter activity
is_a: GO:0140657 ! ATP-dependent activity
+property_value: skos:narrowMatch RHEA:66168
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20237" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22209" xsd:anyURI
created_by: pg
@@ -466262,7 +483123,10 @@
xref: RHEA:30403
is_a: GO:0015453 ! oxidoreduction-driven active transmembrane transporter activity
is_a: GO:0016722 ! oxidoreductase activity, acting on metal ions
+property_value: skos:exactMatch EC:7.2.1.3
+property_value: skos:exactMatch RHEA:30403
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2020-12-18T16:25:06Z
@@ -466294,7 +483158,9 @@
def: "Oxidation of monodehydroascorbate outside of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction." [PMID:1623014, RHEA:66524]
xref: RHEA:66524
is_a: GO:0016491 ! oxidoreductase activity
+property_value: skos:exactMatch RHEA:66524
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20602" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2021-01-07T16:20:04Z
@@ -466345,8 +483211,11 @@
is_a: GO:0005375 ! copper ion transmembrane transporter activity
is_a: GO:0015662 ! P-type ion transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
+property_value: skos:exactMatch EC:7.2.2.8
+property_value: skos:exactMatch RHEA:25792
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20699" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2021-01-18T11:15:13Z
@@ -466369,6 +483238,7 @@
synonym: "chromatin extrusion activity" EXACT []
is_a: GO:0015616 ! DNA translocase activity
relationship: part_of GO:0140588 ! chromatin looping
+property_value: skos:broadMatch RHEA:13065
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20204" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21647" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -466463,6 +483333,9 @@
synonym: "histone-H3R8 methyltransferase activity" EXACT []
is_a: GO:0016274 ! protein-arginine N-methyltransferase activity
is_a: GO:0140938 ! histone H3 methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.319
+property_value: skos:broadMatch EC:2.1.1.320
+property_value: skos:broadMatch RHEA:48108
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20037" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -466658,8 +483531,10 @@
is_a: GO:0005384 ! manganese ion transmembrane transporter activity
is_a: GO:0015662 ! P-type ion transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
+property_value: skos:exactMatch RHEA:66820
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20918" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2021-03-03T22:11:36Z
@@ -466698,12 +483573,13 @@
synonym: "monoiodotyrosine deiodinase activity" RELATED []
synonym: "tyrosine iodinase activity" RELATED []
xref: EC:1.21.1.1
-xref: Reactome:R-HSA-209921 "Monoiodinated tyrosine can be deiodinated"
-xref: Reactome:R-HSA-209960 "Diiodinated tyrosine can be deiodinated"
xref: RHEA:32479
is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond
+property_value: skos:exactMatch EC:1.21.1.1
+property_value: skos:exactMatch RHEA:32479
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21027" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22877" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2021-03-08T15:36:42Z
@@ -466734,7 +483610,10 @@
xref: RHEA:15061
is_a: GO:0000293 ! ferric-chelate reductase activity
is_a: GO:0016723 ! oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.16.1.7
+property_value: skos:exactMatch RHEA:15061
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21029" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
created_by: pg
creation_date: 2021-03-09T07:20:30Z
@@ -467026,7 +483905,10 @@
xref: MetaCyc:HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN
xref: RHEA:14833
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.88
+property_value: skos:exactMatch RHEA:14833
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21411" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2021-05-11T16:00:35Z
@@ -467177,7 +484059,6 @@
synonym: "tryprostatin A synthesis" EXACT []
is_a: GO:0035835 ! indole alkaloid biosynthetic process
is_a: GO:0042435 ! indole-containing compound biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:1901503 ! ether biosynthetic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21495" xsd:anyURI
created_by: pg
@@ -467325,9 +484206,8 @@
synonym: "ATP-dependent DNA damage sensing activity" EXACT []
is_a: GO:0008094 ! ATP-dependent activity, acting on DNA
is_a: GO:0140612 ! DNA damage sensor activity
-intersection_of: GO:0140612 ! DNA damage sensor activity
-intersection_of: has_part GO:0016887 ! ATP hydrolysis activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21662" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30980" xsd:anyURI
created_by: pg
creation_date: 2021-06-19T16:37:21Z
@@ -467344,6 +484224,7 @@
synonym: "histone H3-H4 dimer loading activity" EXACT []
is_a: GO:0000510 ! H3-H4 histone complex chaperone activity
is_a: GO:0140674 ! ATP-dependent histone chaperone activity
+property_value: skos:broadMatch RHEA:13065
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21580" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21733" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -467511,7 +484392,6 @@
namespace: molecular_function
def: "A molecular function regulator that activates or increases the activity of its target via non-covalent binding that does not result in covalent modification to the target." [GOC:curators]
comment: This term should only be used in cases when the regulator directly interacts with the enzyme, but does not result in a covalent modification.
-xref: Reactome:R-HSA-8866941 "MID1IP1 binds THRSP"
is_a: GO:0098772 ! molecular function regulator activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21782" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25165" xsd:anyURI
@@ -467540,6 +484420,9 @@
is_a: GO:0015081 ! sodium ion transmembrane transporter activity
is_a: GO:0019829 ! ATPase-coupled monoatomic cation transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:broadMatch MetaCyc:RXN-17739
+property_value: skos:broadMatch RHEA:14633
+property_value: skos:exactMatch EC:7.2.2.4
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21796" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28176" xsd:anyURI
@@ -467559,8 +484442,11 @@
xref: MetaCyc:RXN-13186
xref: RHEA:42032
is_a: GO:0051864 ! histone H3K36 demethylase activity
+property_value: skos:exactMatch EC:1.14.11.27
+property_value: skos:exactMatch RHEA:42032
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21089" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2021-07-08T14:12:22Z
@@ -467578,8 +484464,11 @@
xref: MetaCyc:RXN-20643
xref: RHEA:60236
is_a: GO:0051864 ! histone H3K36 demethylase activity
+property_value: skos:exactMatch EC:1.14.11.69
+property_value: skos:exactMatch RHEA:60236
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21089" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25808" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2021-07-08T14:12:31Z
@@ -467597,7 +484486,10 @@
xref: RHEA:60244
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
is_a: GO:0032453 ! histone H3K4 demethylase activity
+property_value: skos:exactMatch EC:1.14.99.66
+property_value: skos:exactMatch RHEA:60244
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21089" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2021-07-08T15:45:22Z
@@ -467615,7 +484507,10 @@
xref: RHEA:60188
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0032454 ! histone H3K9 demethylase activity
+property_value: skos:exactMatch EC:1.14.11.65
+property_value: skos:exactMatch RHEA:60188
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21089" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2021-07-09T06:03:06Z
@@ -467633,7 +484528,10 @@
xref: RHEA:60200
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0032454 ! histone H3K9 demethylase activity
+property_value: skos:exactMatch EC:1.14.11.66
+property_value: skos:exactMatch RHEA:60200
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21089" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2021-07-09T06:03:55Z
@@ -467649,6 +484547,7 @@
synonym: "histone H3K9me2 demethylase activity" BROAD []
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
is_a: GO:0032454 ! histone H3K9 demethylase activity
+property_value: skos:broadMatch EC:1.14.11.65
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21089" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -467685,8 +484584,10 @@
comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
xref: RHEA:67952
is_a: GO:0120250 ! fatty acid omega-hydroxylase activity
+property_value: skos:exactMatch RHEA:67952
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21925" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2021-08-05T07:41:17Z
@@ -467729,6 +484630,8 @@
xref: RHEA:58664
is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
is_a: GO:0047545 ! (S)-2-hydroxyglutarate dehydrogenase activity
+property_value: skos:exactMatch EC:1.1.5.13
+property_value: skos:exactMatch RHEA:58664
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21957" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30707" xsd:anyURI
created_by: pg
@@ -467770,6 +484673,7 @@
synonym: "3',2'-cyclic GAMP synthase activity" EXACT []
xref: RHEA:68344
is_a: GO:0140699 ! cyclic GMP-AMP synthase activity
+property_value: skos:exactMatch RHEA:68344
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21980" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30714" xsd:anyURI
created_by: pg
@@ -467785,7 +484689,9 @@
synonym: "3',3'-cyclic GAMP synthase activity" EXACT []
xref: RHEA:35647
is_a: GO:0140699 ! cyclic GMP-AMP synthase activity
+property_value: skos:exactMatch RHEA:35647
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21980" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2021-08-27T05:13:09Z
@@ -467856,7 +484762,7 @@
namespace: biological_process
def: "The C-terminal elongation of 60S-anchored stalled nascent polypeptide chains with untemplated alanine and threonine tails (CAT tails). CAT tails participate in the recognition of stalled nascent chains by the ribosome quality control system." [PMID:25554787, PMID:32934225]
is_a: GO:0002182 ! cytoplasmic translational elongation
-relationship: part_of GO:0072344 ! rescue of stalled ribosome
+relationship: part_of GO:0072344 ! rescue of stalled cytosolic ribosome
relationship: part_of GO:1990116 ! ribosome-associated ubiquitin-dependent protein catabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21987" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23474" xsd:anyURI
@@ -467972,7 +484878,7 @@
id: GO:0140718
name: facultative heterochromatin formation
namespace: biological_process
-def: "The compaction of chromatin into a conformation that is refractory to transcription but that can be converted to euchromatin and allow transcription in specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the periphery or vice versa due to exogenous factors/signals), or parental/heritable (e.g., monoallelic gene expression). In metazoa, this involves the methylation of histone H3K27." [PMID:17936700]
+def: "The compaction of chromatin into a conformation that is refractory to transcription but that can be converted to euchromatin and allow transcription in specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the periphery or vice versa due to exogenous factors/signals), or parental/heritable (e.g., monoallelic gene expression). In metazoa, this involves the methylation of histone H3K27, and in certain cases methylation of H3K9. On the other hand, in unicellular eukaryotes, only methylation of H3K9 is involved and H3K27 is not methylated." [PMID:17936700]
comment: Note that facultative heterochromatin can be reprogrammed, as opposed to constitutive heterochromatin which usually cannot be reprogrammed to a transcriptionally-competent state. Note also that facultative heterochromatin formation does not usually involve DNA methylation, while constitutive heterochromatin formation does.
synonym: "facultative heterochromatin assembly" EXACT []
synonym: "fHC assembly" EXACT []
@@ -467986,7 +484892,7 @@
id: GO:0140719
name: constitutive heterochromatin formation
namespace: biological_process
-def: "The compaction of chromatin into heterochromatin, a conformation that is refractory to transcription. Constitutive heterochromatin cannot be converted back to euchromatin, the transcriptionally-active conformation. In metazoa, this involves the methylation of histone H3K9." [PMID:17936700]
+def: "The compaction of chromatin into heterochromatin, a conformation that is refractory to transcription and in that involves the methylation of histone H3K9. Constitutive heterochromatin cannot be converted back to euchromatin, the transcriptionally-active conformation." [PMID:17936700]
comment: Note that constitutive heterochromatin usually cannot be reprogrammed to a transcriptionally-competent state, as opposed to facultative heterochromatin, which can be reprogrammed. Note also that constitutive usually involves DNA methylation, while facultative heterochromatin formation does not.
synonym: "constitutive heterochromatin assembly" EXACT []
is_a: GO:0031507 ! heterochromatin formation
@@ -468287,11 +485193,15 @@
namespace: molecular_function
def: "Catalysis of the reaction: L-arginyl-[protein] + NAD+ = ADP-riboxanated L-argininyl-[protein] + H+ + NH4(+) + nicotinamide." [PMID:34671164, RHEA:69500]
comment: Note that this activity has two steps: a transfer of an ADP-ribose group, followed by the elimination of an ammonia group.
-xref: Reactome:R-HSA-9956624 "OspC3 ADP-riboxanates CASP4"
xref: RHEA:69500
+xref: RHEA:75883
+xref: RHEA:75887
is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups
is_a: GO:0016841 ! ammonia-lyase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch RHEA:69500
+property_value: skos:narrowMatch RHEA:75883
+property_value: skos:narrowMatch RHEA:75887
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22480" xsd:anyURI
created_by: pg
creation_date: 2021-11-30T08:29:49Z
@@ -468309,8 +485219,11 @@
xref: RHEA:24176
is_a: GO:0016783 ! sulfurtransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch EC:2.8.1.4
+property_value: skos:exactMatch RHEA:24176
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22502" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2021-12-02T12:11:41Z
@@ -468404,6 +485317,7 @@
def: "Catalysis of the reaction: phlorizin + H2O = beta-D-glucose + phloretin." [PMID:9762914, RHEA:69639]
xref: RHEA:69639
is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch RHEA:69639
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22611" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
created_by: pg
@@ -468525,6 +485439,7 @@
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24337" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29636" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-01-28T08:39:20Z
@@ -468572,8 +485487,11 @@
xref: RHEA:47372
is_a: GO:0004344 ! glucose dehydrogenase activity
is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
+property_value: skos:exactMatch EC:1.1.5.9
+property_value: skos:exactMatch RHEA:47372
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22585" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25441" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-02-04T08:02:40Z
@@ -468615,6 +485533,7 @@
synonym: "NAD-dependent histone H3K56 deacetylase activity" EXACT []
is_a: GO:0017136 ! histone deacetylase activity, NAD-dependent
is_a: GO:0141050 ! histone H3K deacetylase activity
+property_value: skos:broadMatch EC:2.3.1.286
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22829" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22836" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -468644,7 +485563,6 @@
synonym: "protein substrate chaperone activity" RELATED []
synonym: "protein-substrate adaptor activity" BROAD []
xref: Reactome:R-HSA-202137 "AKT1 binds eNOS complex via HSP90"
-xref: Reactome:R-HSA-5653886 "B4GALT1 binds LALBA"
is_a: GO:0030674 ! protein-macromolecule adaptor activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22972" xsd:anyURI
created_by: pg
@@ -468667,6 +485585,7 @@
def: "Catalysis of the reaction: L-lysyl-[protein] + tetradecanoyl-[ACP] = H+ + holo-[ACP] + N(6)-tetradecanoyl-L-lysyl-[protein]." [PMID:32461253, RHEA:70611]
xref: RHEA:70611
is_a: GO:0018030 ! peptidyl-lysine N6-myristoyltransferase activity
+property_value: skos:exactMatch RHEA:70611
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22968" xsd:anyURI
created_by: pg
creation_date: 2022-03-02T12:44:18Z
@@ -468678,6 +485597,7 @@
def: "Catalysis of the reaction: L-lysyl-[protein] + tetradecanoyl-CoA = CoA + H+ + N(6)-tetradecanoyl-L-lysyl-[protein]." [PMID:1402651, RHEA:59752]
xref: RHEA:59752
is_a: GO:0018030 ! peptidyl-lysine N6-myristoyltransferase activity
+property_value: skos:exactMatch RHEA:59752
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22968" xsd:anyURI
created_by: pg
creation_date: 2022-03-02T12:45:16Z
@@ -468689,6 +485609,7 @@
def: "Catalysis of the reaction: hexadecanoyl-[ACP] + L-lysyl-[protein] = H+ + holo-[ACP] + N(6)-hexadecanoyl-L-lysyl-[protein]." [PMID:32461253, RHEA:70615]
xref: RHEA:70615
is_a: GO:0018031 ! peptidyl-lysine N6-palmitoyltransferase activity
+property_value: skos:exactMatch RHEA:70615
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22968" xsd:anyURI
created_by: pg
creation_date: 2022-03-02T12:51:53Z
@@ -468698,7 +485619,9 @@
name: CoA-dependent peptidyl-lysine N6-palmitoyltransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: L-lysyl-[protein] + hexadecanoyl-CoA = CoA + H+ + N(6)-hexadecanoyl-L-lysyl-[protein]." [PMID:30061757]
+xref: RHEA:59768
is_a: GO:0018031 ! peptidyl-lysine N6-palmitoyltransferase activity
+property_value: skos:narrowMatch RHEA:59768
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22968" xsd:anyURI
created_by: pg
creation_date: 2022-03-02T12:52:22Z
@@ -468711,7 +485634,9 @@
xref: RHEA:70567
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
relationship: part_of GO:0043687 ! post-translational protein modification
+property_value: skos:exactMatch RHEA:70567
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22875" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-03-02T15:21:37Z
@@ -468723,7 +485648,9 @@
xref: RHEA:70563
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
relationship: part_of GO:0043687 ! post-translational protein modification
+property_value: skos:exactMatch RHEA:70563
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22875" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-03-02T15:23:03Z
@@ -468892,6 +485819,7 @@
def: "Catalysis of the active transport of a phosphate ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged." [PMID:29642010]
is_a: GO:0005315 ! phosphate transmembrane transporter activity
is_a: GO:0022810 ! membrane potential driven uniporter activity
+property_value: skos:broadMatch RHEA:32823
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23132" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
created_by: pg
@@ -468905,6 +485833,7 @@
synonym: "glutamate uniporter activity" BROAD []
is_a: GO:0005313 ! L-glutamate transmembrane transporter activity
is_a: GO:0022810 ! membrane potential driven uniporter activity
+property_value: skos:broadMatch RHEA:66336
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23143" xsd:anyURI
created_by: pg
creation_date: 2022-04-06T07:05:14Z
@@ -468943,6 +485872,7 @@
synonym: "histone H2S140 phosphatase activity" RELATED []
synonym: "histone serine phosphatase activity (H2-S140 specific)" EXACT []
is_a: GO:0140789 ! histone phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.16
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23148" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25037" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -468973,6 +485903,7 @@
synonym: "histone H2Y142 phosphatase activity" RELATED []
synonym: "histone tyrosine phosphatase activity (H2-Y142 specific)" EXACT []
is_a: GO:0140789 ! histone phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.48
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23148" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25037" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
@@ -469004,6 +485935,7 @@
synonym: "histone H3-R2 arginine deiminase activity" EXACT []
synonym: "histone-arginine deiminase activity (H3-R2 specific)" EXACT []
is_a: GO:0141057 ! histone H3 arginine deiminase activity
+property_value: skos:broadMatch EC:3.5.3.15
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23152" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469020,6 +485952,7 @@
synonym: "histone H3-R8 arginine deiminase activity" EXACT []
synonym: "histone-arginine deiminase activity (H3-R8 specific)" EXACT []
is_a: GO:0141057 ! histone H3 arginine deiminase activity
+property_value: skos:broadMatch EC:3.5.3.15
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23152" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469036,6 +485969,7 @@
synonym: "histone H3-R17 arginine deiminase activity" EXACT []
synonym: "histone-arginine deiminase activity (H3-R17 specific)" EXACT []
is_a: GO:0141057 ! histone H3 arginine deiminase activity
+property_value: skos:broadMatch EC:3.5.3.15
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23152" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469052,6 +485986,7 @@
synonym: "histone H3-R26 arginine deiminase activity" EXACT []
synonym: "histone-arginine deiminase activity (H3-R26 specific)" EXACT []
is_a: GO:0141057 ! histone H3 arginine deiminase activity
+property_value: skos:broadMatch EC:3.5.3.15
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23152" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469095,6 +486030,7 @@
synonym: "histone kinase activity (H2AX-Y142 specific)" EXACT []
is_a: GO:0004713 ! protein tyrosine kinase activity
is_a: GO:0141003 ! histone H2AX kinase activity
+property_value: skos:broadMatch RHEA:10596
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23170" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469108,7 +486044,9 @@
def: "Catalysis of the reaction: [protein]-C-terminal glycine + NAD+ = [protein]-C-terminal O-(ADP-D-ribosyl)-glycine + nicotinamide." [PMID:28525742, RHEA:58268]
xref: RHEA:58268
is_a: GO:1990404 ! NAD+-protein mono-ADP-ribosyltransferase activity
+property_value: skos:exactMatch RHEA:58268
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22874" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-05-02T06:45:52Z
@@ -469119,7 +486057,9 @@
def: "Catalysis of the reaction: L-cysteinyl-[protein] + NAD+ = H+ + nicotinamide + S-(ADP-D-ribosyl)-L-cysteinyl-[protein]." [PMID:25043379, RHEA:56612]
xref: RHEA:56612
is_a: GO:1990404 ! NAD+-protein mono-ADP-ribosyltransferase activity
+property_value: skos:exactMatch RHEA:56612
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22874" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-05-02T06:46:09Z
@@ -469130,7 +486070,9 @@
def: "Catalysis of the reaction: L-lysyl-[protein] + NAD+ = H+ + N(6)-(ADP-D-ribosyl)-L-lysyl-[protein] + nicotinamide." [PMID:25043379, RHEA:58220]
xref: RHEA:58220
is_a: GO:1990404 ! NAD+-protein mono-ADP-ribosyltransferase activity
+property_value: skos:exactMatch RHEA:58220
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22874" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-05-02T06:46:22Z
@@ -469141,7 +486083,9 @@
def: "Catalysis of the reaction: L-seryl-[protein] + NAD+ = H+ + nicotinamide + O-(ADP-D-ribosyl)-L-seryl-[protein]." [PMID:32028527, PMID:33186521, RHEA:58232]
xref: RHEA:58232
is_a: GO:1990404 ! NAD+-protein mono-ADP-ribosyltransferase activity
+property_value: skos:exactMatch RHEA:58232
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22874" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-05-02T06:46:35Z
@@ -469152,6 +486096,7 @@
def: "Catalysis of the reaction: L-aspartyl-[protein] + NAD+ = 4-O-(ADP-D-ribosyl)-L-aspartyl-[protein] + nicotinamide." [PMID:19764761, PMID:25043379, RHEA:54424]
xref: RHEA:54424
is_a: GO:1990404 ! NAD+-protein mono-ADP-ribosyltransferase activity
+property_value: skos:exactMatch RHEA:54424
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22874" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
created_by: pg
@@ -469164,6 +486109,7 @@
def: "Catalysis of the reaction: L-glutamyl-[protein] + NAD+ = 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + nicotinamide." [PMID:19764761, PMID:25043379, RHEA:58224]
xref: RHEA:58224
is_a: GO:1990404 ! NAD+-protein mono-ADP-ribosyltransferase activity
+property_value: skos:exactMatch RHEA:58224
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22874" xsd:anyURI
created_by: pg
creation_date: 2022-05-02T06:47:00Z
@@ -469175,7 +486121,9 @@
def: "Catalysis of the reaction: L-tyrosyl-[protein] + NAD+ = H+ + nicotinamide + O-(ADP-D-ribosyl)-L-tyrosyl-[protein]." [PMID:29954836, PMID:30257210, RHEA:58236]
xref: RHEA:58236
is_a: GO:1990404 ! NAD+-protein mono-ADP-ribosyltransferase activity
+property_value: skos:exactMatch RHEA:58236
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22874" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-05-02T06:47:12Z
@@ -469189,6 +486137,7 @@
synonym: "histone H4-R3 arginine deiminase activity" EXACT []
synonym: "histone-arginine deiminase activity (H4-R3 specific)" EXACT []
is_a: GO:0140794 ! histone arginine deiminase activity
+property_value: skos:broadMatch EC:3.5.3.15
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23152" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469205,6 +486154,7 @@
synonym: "histone H1-R54 deiminase activity" EXACT []
synonym: "histone-arginine deiminase activity (H1-R54 specific)" EXACT []
is_a: GO:0140794 ! histone arginine deiminase activity
+property_value: skos:broadMatch EC:3.5.3.15
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23152" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pg
@@ -469220,6 +486170,7 @@
synonym: "histone H2A-R3 arginine deiminase activity" EXACT []
synonym: "histone-arginine deiminase activity (H2A-R3 specific)" EXACT []
is_a: GO:0140794 ! histone arginine deiminase activity
+property_value: skos:broadMatch EC:3.5.3.15
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23152" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469264,7 +486215,9 @@
is_a: GO:0015199 ! amino-acid betaine transmembrane transporter activity
is_a: GO:0015378 ! sodium:chloride symporter activity
relationship: part_of GO:0031460 ! glycine betaine transport
+property_value: skos:exactMatch RHEA:71175
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23298" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-05-12T06:05:59Z
@@ -469275,7 +486228,9 @@
def: "Catalysis of the reaction: L-histidyl-[protein] + NAD+ = H+ + Nt-(ADP-D-ribosyl)-L-histidyl-[protein] + nicotinamide." [PMID:35393539, RHEA:72071]
xref: RHEA:72071
is_a: GO:1990404 ! NAD+-protein mono-ADP-ribosyltransferase activity
+property_value: skos:exactMatch RHEA:72071
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23309" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-05-12T07:49:41Z
@@ -469288,6 +486243,7 @@
synonym: "NAD+-histone H2B-S6 serine ADP-ribosyltransferase activity" EXACT []
synonym: "NAD+-histone-serine ADP-ribosyltransferase activity (H2B-S6 specific)" EXACT []
is_a: GO:0140805 ! NAD+-protein-serine ADP-ribosyltransferase activity
+property_value: skos:broadMatch RHEA:58232
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23309" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469303,6 +486259,7 @@
synonym: "NAD+-histone H3-S10 serine ADP-ribosyltransferase activity" EXACT []
synonym: "NAD+-histone-serine ADP-ribosyltransferase activity (H3-S10 specific)" EXACT []
is_a: GO:0140805 ! NAD+-protein-serine ADP-ribosyltransferase activity
+property_value: skos:broadMatch RHEA:58232
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23309" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469320,9 +486277,12 @@
xref: RHEA:67004
is_a: GO:0016462 ! pyrophosphatase activity
is_a: GO:0140098 ! catalytic activity, acting on RNA
+property_value: skos:exactMatch EC:3.6.1.74
+property_value: skos:exactMatch RHEA:67004
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23319" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25810" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26929" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-05-16T06:01:07Z
@@ -469368,6 +486328,7 @@
synonym: "NAD+-histone H2B-E35 glutamate ADP-ribosyltransferase activity" EXACT []
synonym: "NAD+-histone-glutamate ADP-ribosyltransferase activity (H2B-E35 specific)" EXACT []
is_a: GO:0140807 ! NAD+-protein-glutamate ADP-ribosyltransferase activity
+property_value: skos:broadMatch RHEA:58224
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23323" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469384,6 +486345,7 @@
synonym: "histone kinase activity (H2B-S36 specific)" EXACT []
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0140998 ! histone H2B kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23323" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469398,7 +486360,10 @@
xref: EC:1.11.1.24
xref: RHEA:62620
is_a: GO:0051920 ! peroxiredoxin activity
+property_value: skos:exactMatch EC:1.11.1.24
+property_value: skos:exactMatch RHEA:62620
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23121" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-05-18T14:25:09Z
@@ -469412,8 +486377,11 @@
xref: MetaCyc:PEROXID-RXN
xref: RHEA:56136
is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch EC:1.11.1.7
+property_value: skos:exactMatch RHEA:56136
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23121" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25776" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-05-18T14:39:20Z
@@ -469423,8 +486391,12 @@
namespace: molecular_function
def: "Enables the transfer of zinc from one side of a membrane to the other according to the reaction: H+(out) + Zn2+(in) = H+(in) + Zn2+(out)." [PMID:19366695, PMID:30893306]
comment: Some transporters exchange 1 H+ for a Zn2+ while others are electroneutral and exchange 2 H+.
+xref: RHEA:28839
+xref: RHEA:72627
is_a: GO:0005385 ! zinc ion transmembrane transporter activity
is_a: GO:0051139 ! metal cation:proton antiporter activity
+property_value: skos:narrowMatch RHEA:28839
+property_value: skos:narrowMatch RHEA:72627
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23359" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23874" xsd:anyURI
created_by: pg
@@ -469478,7 +486450,9 @@
is_a: GO:0015186 ! L-glutamine transmembrane transporter activity
is_a: GO:0015385 ! sodium:proton antiporter activity
is_a: GO:0140848 ! amino acid:monoatomic cation antiporter activity
+property_value: skos:exactMatch RHEA:71127
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23382" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-05-24T12:29:37Z
@@ -469491,7 +486465,9 @@
is_a: GO:0015182 ! L-asparagine transmembrane transporter activity
is_a: GO:0015385 ! sodium:proton antiporter activity
is_a: GO:0140848 ! amino acid:monoatomic cation antiporter activity
+property_value: skos:exactMatch RHEA:71131
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23383" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-05-24T12:35:49Z
@@ -469505,7 +486481,9 @@
is_a: GO:0015385 ! sodium:proton antiporter activity
is_a: GO:0045119 ! azole:proton antiporter activity
is_a: GO:0140848 ! amino acid:monoatomic cation antiporter activity
+property_value: skos:exactMatch RHEA:71135
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23384" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-05-24T12:37:29Z
@@ -469516,6 +486494,7 @@
def: "Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphotyrosine (position 1)." [PMID:28248323]
synonym: "RNA polymerase II C-terminal domain Y1 kinase activity" EXACT []
is_a: GO:0008353 ! RNA polymerase II CTD heptapeptide repeat kinase activity
+property_value: skos:broadMatch EC:2.7.11.23
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23389" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pg
@@ -469528,6 +486507,7 @@
def: "Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphoserine (position 2)." [PMID:28248323]
synonym: "RNA polymerase II C-terminal domain S2 kinase activity" EXACT []
is_a: GO:0008353 ! RNA polymerase II CTD heptapeptide repeat kinase activity
+property_value: skos:broadMatch EC:2.7.11.23
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23389" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pg
@@ -469540,6 +486520,7 @@
def: "Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphothreonine (position 4)." [PMID:28248323]
synonym: "RNA polymerase II C-terminal domain T4 kinase activity" EXACT []
is_a: GO:0008353 ! RNA polymerase II CTD heptapeptide repeat kinase activity
+property_value: skos:broadMatch EC:2.7.11.23
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23389" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pg
@@ -469552,6 +486533,7 @@
def: "Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphoserine (position 5)." [PMID:28248323]
synonym: "RNA polymerase II C-terminal domain S5 kinase activity" EXACT []
is_a: GO:0008353 ! RNA polymerase II CTD heptapeptide repeat kinase activity
+property_value: skos:broadMatch EC:2.7.11.23
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23389" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pg
@@ -469564,6 +486546,7 @@
def: "Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphoserine (position 7)." [PMID:28248323]
synonym: "RNA polymerase II C-terminal domain S7 kinase activity" EXACT []
is_a: GO:0008353 ! RNA polymerase II CTD heptapeptide repeat kinase activity
+property_value: skos:broadMatch EC:2.7.11.23
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23389" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pg
@@ -469587,6 +486570,7 @@
def: "Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) cis-proline (omega=180) (position 3) = RNA polymerase II large subunit trans-proline (omega=0) (position 3)." [PMID:28248323]
synonym: "RNA polymerase II C-terminal domain P3 isomerase activity" EXACT []
is_a: GO:0140838 ! RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity
+property_value: skos:broadMatch EC:5.2.1.8
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23389" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pg
@@ -469599,6 +486583,7 @@
def: "Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) cis-proline (omega=180) (position 6) = RNA polymerase II large subunit trans-proline (omega=0) (position 6)." [PMID:28248323]
synonym: "RNA polymerase II C-terminal domain P6 isomerase activity" EXACT []
is_a: GO:0140838 ! RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity
+property_value: skos:broadMatch EC:5.2.1.8
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23389" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pg
@@ -469620,6 +486605,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine (position 5)." [PMID:22605332]
is_a: GO:0140841 ! RNA polymerase II C-terminal domain O-GlcNAc transferase activity
+property_value: skos:broadMatch EC:2.4.1.255
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23389" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pg
@@ -469631,6 +486617,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine (position 7)." [PMID:22605332]
is_a: GO:0140841 ! RNA polymerase II C-terminal domain O-GlcNAc transferase activity
+property_value: skos:broadMatch EC:2.4.1.255
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23389" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pg
@@ -469645,6 +486632,7 @@
synonym: "NAD+-histone H2B-E2 glutamate ADP-ribosyltransferase activity" EXACT []
synonym: "NAD+-histone-glutamate ADP-ribosyltransferase activity (H2B-E2 specific)" EXACT []
is_a: GO:0140807 ! NAD+-protein-glutamate ADP-ribosyltransferase activity
+property_value: skos:broadMatch RHEA:58224
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23377" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469713,6 +486701,7 @@
synonym: "ATP-dependent H2A.Z histone chaperone activity" EXACT []
synonym: "H2AZ histone exchange activity" RELATED []
is_a: GO:0140674 ! ATP-dependent histone chaperone activity
+property_value: skos:broadMatch RHEA:13065
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23463" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: pg
@@ -469767,8 +486756,10 @@
xref: RHEA:59504
is_a: GO:0016740 ! transferase activity
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch RHEA:59504
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23427" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27191" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-06-13T15:08:54Z
@@ -469793,6 +486784,7 @@
synonym: "histone-serine kinase activity (H3-S57 specific)" EXACT []
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0140996 ! histone H3 kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23503" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469807,6 +486799,7 @@
comment: Note that the residue position corresponds to the canonical human H2A2A histone (UniProtKB:Q6FI13); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
synonym: "histone ubiquitin ligase activity (H2A-K13 specific)" EXACT []
is_a: GO:0141053 ! histone H2A ubiquitin ligase activity
+property_value: skos:broadMatch KEGG_REACTION:R03876
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22138" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469824,6 +486817,7 @@
synonym: "histone-threonine kinase activity (H3-T45 specific)" EXACT []
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0140996 ! histone H3 kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23503" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469838,6 +486832,7 @@
comment: Note that the residue position corresponds to the canonical human H2A2A histone (UniProtKB:Q6FI13); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
synonym: "histone ubiquitin ligase activity (H2A-K15 specific)" EXACT []
is_a: GO:0141053 ! histone H2A ubiquitin ligase activity
+property_value: skos:broadMatch KEGG_REACTION:R03876
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22138" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469857,9 +486852,12 @@
xref: EC:4.2.1.139
xref: RHEA:35407
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch EC:4.2.1.139
+property_value: skos:exactMatch RHEA:35407
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23521" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28937" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-06-20T14:36:46Z
@@ -469869,10 +486867,16 @@
namespace: molecular_function
def: "Catalysis of the reaction: a (3R,4R)-4,2'-dihydroxyisoflavan + NADP+ = a (3R)-2'-hydroxyisoflavanone + H+ + NADPH." [PMID:7625843, RHEA:56284]
synonym: "vestitone reductase activity" NARROW [EC:1.1.1.348]
+xref: EC:1.1.1.348
+xref: MetaCyc:RXN-18747
xref: RHEA:56284
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.348
+property_value: skos:exactMatch MetaCyc:RXN-18747
+property_value: skos:exactMatch RHEA:56284
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23521" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: pg
creation_date: 2022-06-20T14:44:54Z
@@ -469897,6 +486901,7 @@
synonym: "histone H2A-K119 ubiquitin ligase activity" EXACT []
synonym: "histone ubiquitin ligase activity (H2A-K119 specific)" EXACT []
is_a: GO:0141053 ! histone H2A ubiquitin ligase activity
+property_value: skos:broadMatch KEGG_REACTION:R03876
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22138" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469912,6 +486917,7 @@
synonym: "histone H2A-K127 ubiquitin ligase activity" EXACT []
synonym: "histone ubiquitin ligase activity (H2A-K127 specific)" EXACT []
is_a: GO:0141053 ! histone H2A ubiquitin ligase activity
+property_value: skos:broadMatch KEGG_REACTION:R03876
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22138" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -469927,6 +486933,7 @@
synonym: "histone H2A-K129 ubiquitin ligase activity" EXACT []
synonym: "histone ubiquitin ligase activity (H2A-K129 specific)" EXACT []
is_a: GO:0141053 ! histone H2A ubiquitin ligase activity
+property_value: skos:broadMatch KEGG_REACTION:R03876
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22138" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -470040,7 +487047,6 @@
is_a: GO:0030639 ! polyketide biosynthetic process
is_a: GO:0042181 ! ketone biosynthetic process
is_a: GO:0043386 ! mycotoxin biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0046189 ! phenol-containing compound biosynthetic process
is_a: GO:0120255 ! olefinic compound biosynthetic process
is_a: GO:1901503 ! ether biosynthetic process
@@ -470435,8 +487441,10 @@
is_a: GO:0005452 ! solute:inorganic anion antiporter activity
is_a: GO:0015108 ! chloride transmembrane transporter activity
is_a: GO:0140829 ! bicarbonate:monoatomic anion antiporter activity
+property_value: skos:exactMatch RHEA:72203
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23828" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26780" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-08-17T14:47:35Z
@@ -470453,6 +487461,8 @@
is_a: GO:0005295 ! neutral L-amino acid:sodium symporter activity
is_a: GO:0015182 ! L-asparagine transmembrane transporter activity
is_a: GO:0015655 ! alanine:sodium symporter activity
+property_value: skos:exactMatch RHEA:71383
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-08-18T05:58:25Z
@@ -470484,6 +487494,9 @@
synonym: "histone-H3R26 methyltransferase activity" EXACT []
is_a: GO:0016274 ! protein-arginine N-methyltransferase activity
is_a: GO:0140938 ! histone H3 methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.319
+property_value: skos:broadMatch EC:2.1.1.320
+property_value: skos:broadMatch RHEA:48108
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23851" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -470516,11 +487529,6 @@
name: halogenase activity
namespace: molecular_function
def: "Catalysis of the reaction: R-CH + a halogen + oxygen donor = R-C-halogen +H2O." [PMID:28466644, PMID:34368824]
-xref: Reactome:R-HSA-209815 "Tyrosine is monoiodinated"
-xref: Reactome:R-HSA-209840 "Two DITs combine to form thyroxine"
-xref: Reactome:R-HSA-209925 "DIT and MIT combine to form triiodothyronine"
-xref: Reactome:R-HSA-209973 "Tyrosine is diiodinated"
-xref: Reactome:R-HSA-350901 "Iodide is organified"
is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23587" xsd:anyURI
created_by: pg
@@ -470547,6 +487555,7 @@
synonym: "histone H3-K122 acetyltransferase activity" EXACT []
synonym: "histone lysine N-acetyltransferase activity (H3-K122 specific)" EXACT []
is_a: GO:0010484 ! histone H3 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28368" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
@@ -470842,7 +487851,12 @@
synonym: "m(7)GpppX diphosphatase activity" EXACT [EC:3.6.1.59]
synonym: "m(7)GpppX pyrophosphatase activity" EXACT [EC:3.6.1.59]
xref: EC:3.6.1.59
+xref: RHEA:65384
+xref: RHEA:65388
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.59
+property_value: skos:narrowMatch RHEA:65384
+property_value: skos:narrowMatch RHEA:65388
created_by: pg
creation_date: 2022-10-24T15:37:32Z
@@ -470855,7 +487869,10 @@
xref: EC:3.6.1.62
xref: RHEA:67484
is_a: GO:0016462 ! pyrophosphatase activity
+property_value: skos:exactMatch EC:3.6.1.62
+property_value: skos:exactMatch RHEA:67484
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23290" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2022-10-24T15:48:42Z
@@ -470906,6 +487923,7 @@
synonym: "histone H4K12 deacetylation" RELATED []
is_a: GO:0141051 ! histone H4K deacetylase activity
is_a: GO:0141221 ! histone deacetylase activity, hydrolytic mechanism
+property_value: skos:broadMatch EC:3.5.1.98
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22769" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29468" xsd:anyURI
@@ -470993,7 +488011,10 @@
xref: EC:2.1.1.362
xref: RHEA:60348
is_a: GO:0042799 ! histone H4K20 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.362
+property_value: skos:exactMatch RHEA:60348
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-11-01T09:25:37Z
@@ -471012,7 +488033,10 @@
xref: EC:2.1.1.368
xref: RHEA:64444
is_a: GO:0046974 ! histone H3K9 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.368
+property_value: skos:exactMatch RHEA:64444
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-11-01T09:35:23Z
@@ -471029,7 +488053,10 @@
xref: EC:2.1.1.372
xref: RHEA:64456
is_a: GO:0042799 ! histone H4K20 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.372
+property_value: skos:exactMatch RHEA:64456
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-11-01T09:44:02Z
@@ -471048,7 +488075,10 @@
xref: EC:2.1.1.361
xref: RHEA:60344
is_a: GO:0042799 ! histone H4K20 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.361
+property_value: skos:exactMatch RHEA:60344
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-11-01T09:50:43Z
@@ -471066,7 +488096,10 @@
xref: EC:2.1.1.364
xref: RHEA:60264
is_a: GO:0042800 ! histone H3K4 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.364
+property_value: skos:exactMatch RHEA:60264
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-11-01T09:57:25Z
@@ -471084,7 +488117,10 @@
xref: EC:2.1.1.370
xref: RHEA:64448
is_a: GO:0042800 ! histone H3K4 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.370
+property_value: skos:exactMatch RHEA:64448
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-11-01T10:01:55Z
@@ -471102,7 +488138,10 @@
xref: EC:2.1.1.366
xref: RHEA:60288
is_a: GO:0046974 ! histone H3K9 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.366
+property_value: skos:exactMatch RHEA:60288
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30382" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
@@ -471121,7 +488160,10 @@
xref: EC:2.1.1.367
xref: RHEA:60280
is_a: GO:0046974 ! histone H3K9 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.367
+property_value: skos:exactMatch RHEA:60280
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30382" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
@@ -471141,7 +488183,10 @@
xref: EC:2.1.1.355
xref: RHEA:60276
is_a: GO:0046974 ! histone H3K9 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.355
+property_value: skos:exactMatch RHEA:60276
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-11-01T10:49:29Z
@@ -471169,9 +488214,13 @@
synonym: "histone H3K27 trimethylase activity" EXACT []
synonym: "histone H3K27 trimethylation" BROAD []
synonym: "histone lysine N-trimethyltransferase activity (H3-K27 specific)" EXACT []
+xref: EC:2.1.1.356
xref: RHEA:60292
is_a: GO:0046976 ! histone H3K27 methyltransferase activity
+property_value: skos:exactMatch RHEA:60292
+property_value: skos:narrowMatch EC:2.1.1.356
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-11-01T13:26:01Z
@@ -471191,7 +488240,10 @@
xref: EC:2.1.1.371
xref: RHEA:64452
is_a: GO:0046976 ! histone H3K27 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.371
+property_value: skos:exactMatch RHEA:64452
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-11-01T14:44:31Z
@@ -471210,7 +488262,10 @@
xref: EC:2.1.1.369
xref: RHEA:60296
is_a: GO:0046976 ! histone H3K27 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.369
+property_value: skos:exactMatch RHEA:60296
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-11-01T14:57:17Z
@@ -471229,7 +488284,10 @@
xref: EC:2.1.1.357
xref: RHEA:60308
is_a: GO:0046975 ! histone H3K36 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.357
+property_value: skos:exactMatch RHEA:60308
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-11-01T15:06:50Z
@@ -471248,7 +488306,10 @@
xref: EC:2.1.1.359
xref: RHEA:60324
is_a: GO:0046975 ! histone H3K36 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.359
+property_value: skos:exactMatch RHEA:60324
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-11-01T15:18:59Z
@@ -471269,6 +488330,9 @@
xref: EC:2.1.1.360
xref: RHEA:60328
is_a: GO:0031151 ! histone H3K79 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.360
+property_value: skos:exactMatch RHEA:60328
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2022-11-01T15:47:14Z
@@ -471552,8 +488616,10 @@
xref: MetaCyc:RXN-19719
xref: RHEA:75279
is_a: GO:0120250 ! fatty acid omega-hydroxylase activity
+property_value: skos:exactMatch RHEA:75279
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24661" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26445" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-01-10T14:42:33Z
@@ -471577,7 +488643,9 @@
xref: RHEA:73059
is_a: GO:0005384 ! manganese ion transmembrane transporter activity
is_a: GO:0015368 ! calcium:monoatomic cation antiporter activity
+property_value: skos:exactMatch RHEA:73059
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24683" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-01-11T15:15:37Z
@@ -471636,7 +488704,9 @@
xref: RHEA:65840
is_a: GO:0005347 ! ATP transmembrane transporter activity
is_a: GO:0015315 ! organophosphate:phosphate antiporter activity
+property_value: skos:exactMatch RHEA:65840
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24780" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-01-26T12:51:22Z
@@ -471650,7 +488720,9 @@
xref: RHEA:65844
is_a: GO:0015217 ! ADP transmembrane transporter activity
is_a: GO:0015315 ! organophosphate:phosphate antiporter activity
+property_value: skos:exactMatch RHEA:65844
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24781" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-01-26T12:53:15Z
@@ -471661,7 +488733,10 @@
def: "Catalysis of the reaction: 7-deoxyloganate + O2 + reduced [NADPH-hemoprotein reductase] = H+ + H2O + loganate + oxidized [NADPH-hemoprotein reductase]." [PMID:24710322, RHEA:57576]
xref: RHEA:57576
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:broadMatch EC:1.14.14.85
+property_value: skos:exactMatch RHEA:57576
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24838" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-02-01T09:58:39Z
@@ -471764,7 +488839,10 @@
xref: EC:2.1.1.354
xref: RHEA:60260
is_a: GO:0042800 ! histone H3K4 methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.354
+property_value: skos:exactMatch RHEA:60260
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22588" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
creation_date: 2023-02-28T12:52:48Z
@@ -471790,6 +488868,7 @@
def: "Catalysis of the reaction: histone H4 L-lysine (position 16) + propionyl-CoA = CoA + H+ + histone H3 N6-propionyl-L-lysyl (position 16)." [PMID:17267393, PMID:29321206, PMID:31794431]
comment: Note that the residue position corresponds to the canonical human H4 histone (UniProtKB:P02309); this residue is conserved across all eukaryotes. Note that the initiation methionine is cleaved, so the first residue is S1.
is_a: GO:0061922 ! histone propionyltransferase activity
+property_value: skos:broadMatch RHEA:54020
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23791" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -471938,7 +489017,9 @@
def: "Hydrolyzes mismatched double-stranded DNA and polynucleotides, releasing free thymine and leaving an apyrimidinic (AP) site." [EC:3.2.2.29, PMID:12711670]
xref: EC:3.2.2.29
is_a: GO:0008263 ! pyrimidine-specific mismatch base pair DNA N-glycosylase activity
+property_value: skos:exactMatch EC:3.2.2.29
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25053" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-03-24T15:23:09Z
@@ -472116,7 +489197,10 @@
xref: RHEA:25948
is_a: GO:0001727 ! lipid kinase activity
is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
+property_value: skos:exactMatch EC:2.7.1.174
+property_value: skos:exactMatch RHEA:25948
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25280" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-04-18T07:14:42Z
@@ -472150,9 +489234,12 @@
xref: Reactome:R-HSA-548818 "HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA"
xref: RHEA:48680
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.1.1.330
+property_value: skos:exactMatch RHEA:48680
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25302" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25805" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25814" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-05-17T11:30:31Z
@@ -472261,6 +489348,8 @@
def: "Removal of an acetyl group from a lysine residue in a histone H3." [GOC:pg, PMID:9893272]
comment: Histone deacytylase (HDAC) enzymes are divided into four classes: the Class I Rpd3-like proteins (in human: HDAC1, HDAC2, HDAC3, and HDAC8); the Class II Hda1-like proteins (in human: HDAC4, HDAC5, HDAC6, HDAC7, HDAC9, and HDAC10); the Class III Sir2-like proteins (in human: SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, and SIRT7); and the Class IV protein (HDAC11 in human). Except for Class III enzymes, the mechanism is a metal-dependent hydrolysis of the acetylated substrate. The Class III HDACs use NAD+ as a reactant to deacetylate acetyl lysine residues of protein substrates forming nicotinamide, the deacetylated product, and the metabolite 2'-O-acetyl-ADP-ribose. Therefore, Class III are classified as transferases (EC:2) and others are hydrolases (EC:3).
is_a: GO:0004407 ! histone deacetylase activity
+property_value: skos:broadMatch EC:2.3.1.-
+property_value: skos:broadMatch EC:3.5.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22836" xsd:anyURI
created_by: pg
creation_date: 2024-09-20T11:40:05Z
@@ -472272,6 +489361,8 @@
def: "Removal of an acetyl group from a lysine residue in a histone H4." [PMID:12590135]
comment: Histone deacytylase (HDAC) enzymes are divided into four classes: the Class I Rpd3-like proteins (in human: HDAC1, HDAC2, HDAC3, and HDAC8); the Class II Hda1-like proteins (in human: HDAC4, HDAC5, HDAC6, HDAC7, HDAC9, and HDAC10); the Class III Sir2-like proteins (in human: SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, and SIRT7); and the Class IV protein (HDAC11 in human). Except for Class III enzymes, the mechanism is a metal-dependent hydrolysis of the acetylated substrate. The Class III HDACs use NAD+ as a reactant to deacetylate acetyl lysine residues of protein substrates forming nicotinamide, the deacetylated product, and the metabolite 2'-O-acetyl-ADP-ribose. Therefore, Class III are classified as transferases (EC:2) and others are hydrolases (EC:3).
is_a: GO:0004407 ! histone deacetylase activity
+property_value: skos:broadMatch EC:2.3.1.-
+property_value: skos:broadMatch EC:3.5.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25508" xsd:anyURI
created_by: pg
creation_date: 2023-06-07T09:15:53Z
@@ -472749,7 +489840,6 @@
namespace: molecular_function
def: "Binding to and responding, e.g. by conformational change, to changes in the cellular level of glucose." [PMID:17470517]
synonym: "glucose sensing activity" EXACT []
-xref: Reactome:R-HSA-170810 "nucleoplasmic GCK1:GCKR complex => glucokinase (GCK1) + glucokinase regulatory protein (GCKR)"
is_a: GO:0140299 ! molecular sensor activity
relationship: has_part GO:0005536 ! D-glucose binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25267" xsd:anyURI
@@ -472765,7 +489855,9 @@
synonym: "protein serine pyrophosphatase activity" RELATED []
xref: RHEA:64104
is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor
+property_value: skos:exactMatch RHEA:64104
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25934" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-08-21T07:53:21Z
@@ -472807,7 +489899,10 @@
xref: MetaCyc:RXN-19229
xref: RHEA:55200
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch EC:2.5.1.147
+property_value: skos:exactMatch RHEA:55200
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25983" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-09-07T11:46:06Z
@@ -472868,6 +489963,9 @@
xref: MetaCyc:RXN-11860
xref: RHEA:43084
is_a: GO:0016427 ! tRNA (cytidine) methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.207
+property_value: skos:exactMatch MetaCyc:RXN-11860
+property_value: skos:exactMatch RHEA:43084
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26084" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30714" xsd:anyURI
created_by: pg
@@ -472883,7 +489981,10 @@
xref: MetaCyc:2.1.1.34-RXN
xref: RHEA:20077
is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.34
+property_value: skos:exactMatch RHEA:20077
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26085" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-09-12T12:15:59Z
@@ -472898,7 +489999,10 @@
xref: Reactome:R-HSA-6788707 "TRMT44 2'-O-methylates uridine-44 in tRNA(Ser)"
xref: RHEA:43100
is_a: GO:0016300 ! tRNA (uridine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.211
+property_value: skos:exactMatch RHEA:43100
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26145" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-09-19T10:20:05Z
@@ -472910,7 +490014,10 @@
synonym: "tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase activity" EXACT []
xref: RHEA:43088
is_a: GO:0016300 ! tRNA (uridine) methyltransferase activity
+property_value: skos:broadMatch EC:2.1.1.207
+property_value: skos:exactMatch RHEA:43088
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26145" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-09-19T10:47:21Z
@@ -473092,10 +490199,11 @@
namespace: molecular_function
def: "Catalysis of the reaction: Fe(II)-heme b-[protein] + nitric oxide + O2 = Fe(III)-heme b-[protein] + nitrate." [PMID:20511233]
comment: Note that this activity is similar to nitric oxide dioxygenase activity ; GO:0008941, but GO:000894 uses NADPH as the electron donor.
-xref: Reactome:R-HSA-5340226 "CYGB dioxygenates NO"
xref: RHEA:78091
is_a: GO:0016675 ! oxidoreductase activity, acting on a heme group of donors
+property_value: skos:exactMatch RHEA:78091
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26482" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-11-23T12:37:09Z
@@ -473122,7 +490230,9 @@
def: "Catalysis of the breakage of a nitrogen-oxygen bond by means other than hydrolysis and oxidation." [EC:4.8.1.-]
xref: EC:4.8.1.-
is_a: GO:0016829 ! lyase activity
+property_value: skos:exactMatch EC:4.8.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24927" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30699" xsd:anyURI
created_by: pg
creation_date: 2023-12-01T13:17:35Z
@@ -473159,7 +490269,9 @@
xref: RHEA:78231
is_a: GO:0035250 ! UDP-galactosyltransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch RHEA:78231
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26593" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-12-08T08:08:35Z
@@ -473172,7 +490284,10 @@
xref: MetaCyc:3.1.2.18-RXN
xref: RHEA:68180
is_a: GO:0047617 ! fatty acyl-CoA hydrolase activity
+property_value: skos:exactMatch RHEA:68180
+property_value: skos:relatedMatch EC:3.1.2.18
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26441" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-12-08T09:05:55Z
@@ -473238,8 +490353,11 @@
xref: RHEA:49524
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0035514 ! DNA demethylase activity
+property_value: skos:exactMatch EC:1.14.11.51
+property_value: skos:exactMatch RHEA:49524
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26656" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29802" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-12-15T15:38:23Z
@@ -473269,7 +490387,10 @@
xref: RHEA:42652
is_a: GO:0008276 ! protein methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.314
+property_value: skos:exactMatch RHEA:42652
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25281" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2023-12-20T09:06:24Z
@@ -473417,10 +490538,17 @@
namespace: molecular_function
def: "Catalysis of the reaction: a 2,3-saturated acyl-[ACP] + NADP+ = a (2E)-enoyl-[ACP] + H+ + NADPH." [RHEA:22564]
comment: This reaction completes each cycle of fatty acid elongation by catalyzing the stereospecific reduction of the double bond at position 2 of a growing fatty acid chain, while linked to the acyl- carrier protein, in an NADPH-dependent manner. Note that EC has reactions describing the stereo-specificity of the reaction with respect to NADP+ (cf. EC 1.3.1.39, EC 1.3.1.10 and EC 1.3.1.104).
+xref: EC:1.3.1.10
xref: EC:1.3.1.104
+xref: EC:1.3.1.39
xref: MetaCyc:ENOYL-ACP-REDUCT-NADPH-RXN
xref: RHEA:22564
is_a: GO:0016631 ! enoyl-[acyl-carrier-protein] reductase [NAD(P)H] activity
+property_value: skos:exactMatch EC:1.3.1.104
+property_value: skos:exactMatch MetaCyc:ENOYL-ACP-REDUCT-NADPH-RXN
+property_value: skos:exactMatch RHEA:22564
+property_value: skos:narrowMatch EC:1.3.1.10
+property_value: skos:narrowMatch EC:1.3.1.39
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25699" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28173" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30035" xsd:anyURI
@@ -473496,6 +490624,8 @@
xref: MetaCyc:1.1.1.8-RXN
xref: RHEA:11092
is_a: GO:0047952 ! glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch EC:1.1.1.8
+property_value: skos:exactMatch RHEA:11092
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21790" xsd:anyURI
created_by: pg
creation_date: 2024-01-30T10:47:46Z
@@ -473511,6 +490641,7 @@
xref: KEGG_REACTION:R00844
xref: RHEA:11096
is_a: GO:0047952 ! glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
+property_value: skos:exactMatch RHEA:11096
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21790" xsd:anyURI
created_by: pg
creation_date: 2024-01-30T15:48:01Z
@@ -473936,7 +491067,9 @@
xref: Reactome:R-HSA-9825790 "p-S207 KARS1 dimer synthesizes A(5')p4(5')A"
xref: RHEA:34935
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch RHEA:34935
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27575" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2024-04-11T10:31:20Z
@@ -474000,7 +491133,10 @@
xref: MetaCyc:RXN-15878
xref: RHEA:43604
is_a: GO:0052592 ! oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
+property_value: skos:exactMatch EC:1.17.7.3
+property_value: skos:exactMatch RHEA:43604
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27696" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pg
creation_date: 2024-04-23T08:04:46Z
@@ -474035,6 +491171,7 @@
def: "Catalysis of the reaction: UTP + thiamine = UMP + thiamine diphosphate." [PMID:38547260, RHEA:79423]
xref: RHEA:79423
is_a: GO:0016778 ! diphosphotransferase activity
+property_value: skos:exactMatch RHEA:79423
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27518" xsd:anyURI
created_by: pg
creation_date: 2024-04-30T07:07:13Z
@@ -474084,8 +491221,11 @@
synonym: "peptide lactyltransferase (ATP dependent) activity" EXACT []
synonym: "peptide lactyltransferase activity" BROAD []
xref: RHEA:80271
+xref: RHEA:80275
is_a: GO:0016886 ! ligase activity, forming phosphoric ester bonds
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch RHEA:80271
+property_value: skos:narrowMatch RHEA:80275
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28015" xsd:anyURI
created_by: pg
creation_date: 2024-06-07T08:13:32Z
@@ -474098,6 +491238,7 @@
synonym: "protein lysine delactylase activity" BROAD []
xref: RHEA:80287
is_a: GO:0034979 ! NAD-dependent protein lysine deacetylase activity
+property_value: skos:exactMatch RHEA:80287
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28015" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28920" xsd:anyURI
created_by: pg
@@ -474158,6 +491299,7 @@
def: "Catalysis of the reaction: N-acetyltaurine + H2O = acetate + taurine." [PMID:39112712, RHEA:81107]
xref: RHEA:81107
is_a: GO:0016788 ! hydrolase activity, acting on ester bonds
+property_value: skos:exactMatch RHEA:81107
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28746" xsd:anyURI
created_by: pg
creation_date: 2024-08-23T09:58:14Z
@@ -474185,6 +491327,7 @@
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
is_a: GO:0140096 ! catalytic activity, acting on a protein
is_a: GO:0160215 ! deacylase activity
+property_value: skos:exactMatch RHEA:54172
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28920" xsd:anyURI
created_by: pg
creation_date: 2024-09-19T14:13:12Z
@@ -474202,6 +491345,8 @@
xref: RHEA:58196
is_a: GO:0004407 ! histone deacetylase activity
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch EC:3.5.1.98
+property_value: skos:exactMatch RHEA:58196
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22836" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29468" xsd:anyURI
created_by: pg
@@ -474215,6 +491360,7 @@
comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
is_a: GO:0017136 ! histone deacetylase activity, NAD-dependent
is_a: GO:0141050 ! histone H3K deacetylase activity
+property_value: skos:broadMatch EC:2.3.1.286
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28994" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pg
@@ -474228,6 +491374,7 @@
synonym: "cysteine synthase activity" BROAD []
xref: RHEA:53816
is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups
+property_value: skos:exactMatch RHEA:53816
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28833" xsd:anyURI
created_by: pg
creation_date: 2024-10-28T07:48:43Z
@@ -474635,16 +491782,14 @@
[Term]
id: GO:0150047
-name: G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential
+name: obsolete G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential
namespace: molecular_function
-def: "G protein-coupled neurotransmitter receptor activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential." [GOC:aruk, GOC:bc, PMID:11498050]
-subset: goslim_synapse
+def: "OBSOLETE. G protein-coupled neurotransmitter receptor activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential." [GOC:aruk, GOC:bc, PMID:11498050]
+comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
synonym: "G-protein coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential" EXACT []
-is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity
-intersection_of: GO:0099528 ! G protein-coupled neurotransmitter receptor activity
-intersection_of: part_of GO:0099505 ! regulation of presynaptic membrane potential
-relationship: occurs_in GO:0042734 ! presynaptic membrane
-relationship: part_of GO:0099505 ! regulation of presynaptic membrane potential
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31205" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0099528
created_by: bc
creation_date: 2018-04-23T10:51:20Z
@@ -475975,6 +493120,8 @@
def: "Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[protein] = (2E)-2-butenoate + L-lysyl-[protein]." [PMID:28497810, PMID:30279482, PMID:34608293]
xref: RHEA:69172
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch RHEA:69172
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2021-11-16T00:55:21Z
@@ -475996,6 +493143,8 @@
def: "Catalysis of the reaction: H2O + N6-(2-hydroxyisobutanoyl)-L-lysyl-[protein] = 2-hydroxy-2-methylpropanoate + L-lysyl-[protein]." [PMID:29192674]
xref: RHEA:69176
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch RHEA:69176
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2021-11-16T01:15:34Z
@@ -476006,6 +493155,8 @@
def: "Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[protein] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide." [PMID:28497810]
xref: RHEA:69332
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch RHEA:69332
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2021-11-16T01:22:43Z
@@ -476028,6 +493179,8 @@
def: "Catalysis of the reaction: H2O + N6-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + NAD+ = 2''-O-(2-hydroxyisobutanoyl)-ADP-D-ribose + L-lysyl-[protein] + nicotinamide." [PMID:31328167]
xref: RHEA:24364
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch RHEA:24364
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2021-11-16T01:28:33Z
@@ -476057,8 +493210,10 @@
xref: RHEA:76235
is_a: GO:0070567 ! cytidylyltransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch RHEA:76235
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25021" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2023-02-28T20:51:52Z
@@ -476407,7 +493562,9 @@
def: "Catalysis of the reaction: ATP + muramyl dipeptide = ADP + H+ + 6-O-phospho-muramyl dipeptide." [PMID:36002575]
xref: RHEA:75935
is_a: GO:0016301 ! kinase activity
+property_value: skos:exactMatch RHEA:75935
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25141" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2023-03-17T22:29:32Z
@@ -476764,6 +493921,7 @@
xref: Reactome:R-HSA-429767 "Passive I- efflux mediated by SLC5A8"
is_a: GO:0005253 ! monoatomic anion channel activity
is_a: GO:0015111 ! iodide transmembrane transporter activity
+property_value: skos:broadMatch RHEA:66324
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25578" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
created_by: rynl
@@ -476779,7 +493937,10 @@
xref: EC:1.14.11.29
xref: RHEA:48400
is_a: GO:0031545 ! peptidyl-proline 4-dioxygenase activity
+property_value: skos:exactMatch EC:1.14.11.29
+property_value: skos:exactMatch RHEA:48400
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25739" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2023-07-13T17:38:59Z
@@ -476835,6 +493996,7 @@
xref: RHEA:60508
is_a: GO:0008174 ! mRNA methyltransferase activity
relationship: part_of GO:0036265 ! RNA (guanine-N7)-methylation
+property_value: skos:exactMatch RHEA:60508
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25788" xsd:anyURI
created_by: rynl
creation_date: 2023-08-08T22:40:38Z
@@ -476923,7 +494085,10 @@
xref: RHEA:43124
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.213
+property_value: skos:exactMatch RHEA:43124
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26104" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2023-09-14T00:15:09Z
@@ -476939,7 +494104,10 @@
xref: RHEA:43128
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.214
+property_value: skos:exactMatch RHEA:43128
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26104" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2023-09-14T00:20:53Z
@@ -476954,7 +494122,10 @@
xref: RHEA:43136
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.215
+property_value: skos:exactMatch RHEA:43136
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26104" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2023-09-14T00:24:30Z
@@ -476971,7 +494142,10 @@
xref: RHEA:43140
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.216
+property_value: skos:exactMatch RHEA:43140
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26104" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2023-09-14T00:28:33Z
@@ -476985,7 +494159,10 @@
xref: EC:2.1.1.217
xref: RHEA:43144
is_a: GO:0016426 ! tRNA (adenine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.217
+property_value: skos:exactMatch RHEA:43144
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26104" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2023-09-14T00:42:44Z
@@ -477001,7 +494178,10 @@
xref: Reactome:R-HSA-6787594 "TRMT10C:HSD17B10 (TRMT10C:SDR5C1) methylates adenosine-9 in tRNA yielding 1-methyladenosine-9"
xref: RHEA:43148
is_a: GO:0016426 ! tRNA (adenine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.218
+property_value: skos:exactMatch RHEA:43148
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26104" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2023-09-14T00:53:53Z
@@ -477018,7 +494198,10 @@
xref: Reactome:R-HSA-6787525 "TRMT61B methylates adenosine-58 in tRNA yielding 1-methyladenosine-58"
xref: RHEA:43152
is_a: GO:0016426 ! tRNA (adenine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.220
+property_value: skos:exactMatch RHEA:43152
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26104" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2023-09-14T00:57:53Z
@@ -477123,7 +494306,10 @@
xref: RHEA:51116
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.256
+property_value: skos:exactMatch RHEA:51116
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26306" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2023-10-26T23:14:33Z
@@ -477169,7 +494355,9 @@
def: "Catalysis of the reaction: 2 3-acyl-sn-glycero-1-phospho-(1'-sn-glycerol) = 3-acyl-sn-glycero-1-phospho-(3'-acyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol)." [PMID:37708259, RHEA:77619]
xref: RHEA:77619
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:exactMatch RHEA:77619
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26277" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2023-10-30T17:31:01Z
@@ -477233,7 +494421,7 @@
name: protein-RNA covalent cross-linking repair
namespace: biological_process
def: "A process that rescues stalled ribosomes by removing the covalent cross-link between RNA and a protein." [PMID:37951215, PMID:37951216]
-is_a: GO:0072344 ! rescue of stalled ribosome
+is_a: GO:0072344 ! rescue of stalled cytosolic ribosome
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26415" xsd:anyURI
created_by: rynl
creation_date: 2023-11-27T19:54:13Z
@@ -477260,6 +494448,7 @@
def: "Catalysis of the cross-link between a protein and a DNA abasic site, forming a thiazolidine linkage between a DNA ring-opened abasic site and the alpha-amino and sulfhydryl substituents of cysteine residue of the protein." [PMID:30554877, PMID:31235913]
xref: MetaCyc:RXN-21016
is_a: GO:0016829 ! lyase activity
+property_value: skos:narrowMatch MetaCyc:RXN-21016
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26415" xsd:anyURI
created_by: rynl
creation_date: 2023-12-06T17:33:59Z
@@ -477305,6 +494494,7 @@
synonym: "hydrogencarbonate channel activity" EXACT []
is_a: GO:0015106 ! bicarbonate transmembrane transporter activity
is_a: GO:0015267 ! channel activity
+property_value: skos:broadMatch RHEA:28695
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26601" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26780" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI
@@ -477340,7 +494530,10 @@
xref: EC:5.4.99.19
xref: RHEA:38867
is_a: GO:0120159 ! rRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.19
+property_value: skos:exactMatch RHEA:38867
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26618" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-09T00:40:24Z
@@ -477352,7 +494545,10 @@
xref: EC:5.4.99.20
xref: RHEA:38871
is_a: GO:0120159 ! rRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.20
+property_value: skos:exactMatch RHEA:38871
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26618" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-09T00:52:51Z
@@ -477364,7 +494560,10 @@
xref: EC:5.4.99.21
xref: RHEA:38875
is_a: GO:0120159 ! rRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.21
+property_value: skos:exactMatch RHEA:38875
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26618" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-09T00:57:29Z
@@ -477376,7 +494575,10 @@
xref: EC:5.4.99.22
xref: RHEA:42520
is_a: GO:0120159 ! rRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.22
+property_value: skos:exactMatch RHEA:42520
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26618" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-09T01:03:34Z
@@ -477388,7 +494590,10 @@
xref: EC:5.4.99.23
xref: RHEA:42524
is_a: GO:0120159 ! rRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.23
+property_value: skos:exactMatch RHEA:42524
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26618" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-09T01:08:10Z
@@ -477400,7 +494605,10 @@
xref: EC:5.4.99.24
xref: RHEA:42528
is_a: GO:0120159 ! rRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.24
+property_value: skos:exactMatch RHEA:42528
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26618" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-09T01:12:45Z
@@ -477412,7 +494620,10 @@
xref: EC:5.4.99.29
xref: RHEA:42548
is_a: GO:0120159 ! rRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.29
+property_value: skos:exactMatch RHEA:42548
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26618" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-09T01:16:13Z
@@ -477424,7 +494635,10 @@
xref: EC:5.4.99.43
xref: RHEA:42556
is_a: GO:0120159 ! rRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.43
+property_value: skos:exactMatch RHEA:42556
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26618" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-09T01:19:05Z
@@ -477457,14 +494671,17 @@
id: GO:0160147
name: tRNA pseudouridine(38-40) synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA." [EC:5.4.99.12]
+def: "Catalysis of the reaction: uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA. Modifies uridine(38), uridine(39) and/or uridine(40) in tRNA." [EC:5.4.99.12]
synonym: "PSUI activity" EXACT [EC:5.4.99.12]
synonym: "tRNA pseudouridylate synthase" EXACT [EC:5.4.99.12]
xref: EC:5.4.99.12
xref: MetaCyc:TRNA-PSEUDOURIDINE-SYNTHASE-I-RXN
xref: RHEA:22376
is_a: GO:0106029 ! tRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.12
+property_value: skos:exactMatch RHEA:22376
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26797" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-17T01:55:49Z
@@ -477476,7 +494693,10 @@
xref: EC:5.4.99.25
xref: RHEA:42532
is_a: GO:0106029 ! tRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.25
+property_value: skos:exactMatch RHEA:42532
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26797" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-17T18:49:10Z
@@ -477488,7 +494708,10 @@
xref: EC:5.4.99.26
xref: RHEA:42536
is_a: GO:0106029 ! tRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.26
+property_value: skos:exactMatch RHEA:42536
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26797" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-17T18:52:17Z
@@ -477500,7 +494723,10 @@
xref: EC:5.4.99.27
xref: RHEA:42540
is_a: GO:0106029 ! tRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.27
+property_value: skos:exactMatch RHEA:42540
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26797" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-17T18:54:10Z
@@ -477512,7 +494738,10 @@
xref: EC:5.4.99.28
xref: RHEA:42544
is_a: GO:0106029 ! tRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.28
+property_value: skos:exactMatch RHEA:42544
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26797" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-17T19:03:23Z
@@ -477524,7 +494753,10 @@
xref: EC:5.4.99.42
xref: RHEA:42552
is_a: GO:0106029 ! tRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.42
+property_value: skos:exactMatch RHEA:42552
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26797" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-17T19:05:18Z
@@ -477536,7 +494768,10 @@
xref: EC:5.4.99.44
xref: RHEA:42560
is_a: GO:0106029 ! tRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.44
+property_value: skos:exactMatch RHEA:42560
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26797" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-01-17T19:07:07Z
@@ -477544,11 +494779,15 @@
id: GO:0160154
name: tRNA pseudouridine(38/39) synthase activity
namespace: molecular_function
-def: "Catalysis of the reaction: uridine(38/39) in tRNA = pseudouridine(38/39) in tRNA." [EC:5.4.99.45]
+def: "Catalysis of the reaction: uridine(38/39) in tRNA = pseudouridine(38/39) in tRNA. Modifies uridine(38) and/or uridine(39) in tRNA." [EC:5.4.99.45]
xref: EC:5.4.99.45
xref: RHEA:42564
is_a: GO:0106029 ! tRNA pseudouridine synthase activity
+property_value: skos:exactMatch EC:5.4.99.45
+property_value: skos:exactMatch RHEA:42564
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26797" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30875" xsd:anyURI
created_by: rynl
creation_date: 2024-01-17T19:11:20Z
@@ -477660,7 +494899,9 @@
def: "Catalysis of the reaction: H+ + NADPH + S-nitrosoglutathione = NADP+ + S-(hydroxysulfenamide)glutathione." [RHEA:63500]
xref: RHEA:63500
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:63500
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27135" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-02-28T01:46:34Z
@@ -477696,6 +494937,7 @@
def: "Catalysis of the reaction: 2-oxoadipate + H+ + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] = CO2 + N(6)-[(R)-S(8)-glutaryldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase]." [PMID:29191460, PMID:32695416, RHEA:69576]
xref: RHEA:69576
is_a: GO:0016624 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
+property_value: skos:exactMatch RHEA:69576
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27202" xsd:anyURI
created_by: rynl
creation_date: 2024-03-06T18:27:05Z
@@ -477848,7 +495090,6 @@
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of piperine." [PMID:33435446, PMID:33833371]
is_a: GO:0009821 ! alkaloid biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27622" xsd:anyURI
created_by: rynl
creation_date: 2024-04-24T20:31:20Z
@@ -477866,6 +495107,8 @@
xref: EC:1.7.5.1
xref: RHEA:56144
is_a: GO:0008940 ! nitrate reductase activity
+property_value: skos:exactMatch EC:1.7.5.1
+property_value: skos:exactMatch RHEA:56144
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27675" xsd:anyURI
created_by: rynl
creation_date: 2024-04-24T22:45:01Z
@@ -477898,7 +495141,7 @@
namespace: molecular_function
def: "Binds to and increases the activity of the enzyme phospholipase C." [PMID:28130414]
is_a: GO:0016004 ! phospholipase activator activity
-relationship: positively_regulates GO:0004629 ! phospholipase C activity
+relationship: positively_regulates GO:0004629 ! C-type glycerophospholipase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27845" xsd:anyURI
created_by: rynl
creation_date: 2024-05-06T23:18:59Z
@@ -477909,7 +495152,7 @@
namespace: molecular_function
def: "Binds to and stops, prevents or reduces the activity of the enzyme phospholipase C." [PMID:28130414]
is_a: GO:0004859 ! phospholipase inhibitor activity
-relationship: negatively_regulates GO:0004629 ! phospholipase C activity
+relationship: negatively_regulates GO:0004629 ! C-type glycerophospholipase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27845" xsd:anyURI
created_by: rynl
creation_date: 2024-05-06T23:26:17Z
@@ -477965,8 +495208,21 @@
def: "Catalysis of the reaction: a C28-steroid + O2 + reduced NADPH--hemoprotein reductase = a (22S)-22-hydroxy C28-steroid + H+ + H2O + oxidized NADPH--hemoprotein reductase. Also catalyzes the C-22 hydroxylation of a variety of C27 and C29 steroids." [EC:1.14.14.178]
synonym: "steroid C-22 hydroxylase activity" EXACT [EC:1.14.14.178]
xref: EC:1.14.14.178
+xref: MetaCyc:RXN-22825
+xref: MetaCyc:RXN-22826
+xref: MetaCyc:RXN-22827
+xref: RHEA:70059
+xref: RHEA:70063
+xref: RHEA:70067
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.14.178
+property_value: skos:narrowMatch MetaCyc:RXN-22825
+property_value: skos:narrowMatch MetaCyc:RXN-22826
+property_value: skos:narrowMatch MetaCyc:RXN-22827
+property_value: skos:narrowMatch RHEA:70059
+property_value: skos:narrowMatch RHEA:70063
+property_value: skos:narrowMatch RHEA:70067
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28221" xsd:anyURI
created_by: rynl
creation_date: 2024-06-27T00:40:39Z
@@ -478027,9 +495283,10 @@
def: "Catalysis of the reaction: a di-trans,poly-cis-polyprenol + NAD+ = a di-trans,poly-cis-polyprenal + NADH + H+." [PMID:38821050, RHEA:80719]
synonym: "polyprenol dehydrogenase activity" BROAD []
xref: MetaCyc:RXN-24567
-xref: Reactome:R-HSA-9937298 "DHRSX oxidizes polyprenol to polyprenal"
xref: RHEA:80719
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.1.1.441
+property_value: skos:exactMatch RHEA:80719
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28566" xsd:anyURI
created_by: rynl
creation_date: 2024-07-25T00:44:15Z
@@ -478044,6 +495301,8 @@
xref: MetaCyc:RXN-24568
xref: RHEA:80731
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:broadMatch EC:1.1.1.441
+property_value: skos:exactMatch RHEA:80731
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28566" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30105" xsd:anyURI
created_by: rynl
@@ -478056,10 +495315,12 @@
def: "Catalysis of the reaction: ditrans,polycis-polyprenal+ H+ + NADPH = ditrans,polycis-dolichal+ NADP." [PMID:38821050, RHEA:80727]
xref: EC:1.3.1.94
xref: MetaCyc:RXN-9971
-xref: Reactome:R-HSA-9937295 "SRD5A3 reduces polyprenal to dolichal"
xref: RHEA:80727
is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch EC:1.3.1.94
+property_value: skos:exactMatch RHEA:80727
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28566" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-07-25T05:51:59Z
@@ -478131,7 +495392,10 @@
xref: EC:2.4.2.60
xref: RHEA:55708
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.60
+property_value: skos:exactMatch RHEA:55708
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28713" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-08-20T00:05:09Z
@@ -478142,9 +495406,13 @@
def: "Catalysis of the reaction: cytidine(32)/uridine(32) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(32)/2'-O-methyluridine(32) in tRNA + H+ + S-adenosyl-L-homocysteine." [EC:2.1.1.200]
synonym: "TrMet(Xm32) activity" EXACT []
xref: EC:2.1.1.200
+xref: RHEA:42936
is_a: GO:0016300 ! tRNA (uridine) methyltransferase activity
is_a: GO:0016427 ! tRNA (cytidine) methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.200
+property_value: skos:narrowMatch RHEA:42936
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28550" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-08-21T21:13:17Z
@@ -478190,7 +495458,9 @@
def: "Catalysis of the reaction: L-serine + succinyl-CoA = CoA + O-succinyl-L-serine." [PMID:28581482, RHEA:52820]
xref: RHEA:52820
is_a: GO:0016750 ! O-succinyltransferase activity
+property_value: skos:exactMatch RHEA:52820
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28832" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-09-04T23:29:11Z
@@ -478243,6 +495513,9 @@
namespace: molecular_function
def: "Catalysis of the reaction: R-CO-X + H2O = R-COOH + HX, hydrolysis of an acyl group or groups from a substrate molecule." [PMID:2760018, PMID:29637793, PMID:38355760]
is_a: GO:0003824 ! catalytic activity
+property_value: skos:broadMatch EC:2.3.1.-
+property_value: skos:broadMatch EC:3.1.1.-
+property_value: skos:broadMatch EC:3.5.1.-
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28920" xsd:anyURI
created_by: rynl
creation_date: 2024-09-16T23:45:30Z
@@ -478255,7 +495528,9 @@
xref: RHEA:81387
is_a: GO:0140096 ! catalytic activity, acting on a protein
is_a: GO:0160215 ! deacylase activity
+property_value: skos:exactMatch RHEA:81387
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28920" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-09-17T00:03:19Z
@@ -478281,7 +495556,6 @@
synonym: "negative regulation of acetyl-CoA biosynthetic process from pyruvate" EXACT []
is_a: GO:0009890 ! negative regulation of biosynthetic process
is_a: GO:0010510 ! regulation of pyruvate decarboxylation to acetyl-CoA
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process
is_a: GO:0045936 ! negative regulation of phosphate metabolic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
@@ -478315,6 +495589,8 @@
xref: MetaCyc:RXN-11298
xref: RHEA:37347
is_a: GO:0016875 ! ligase activity, forming carbon-oxygen bonds
+property_value: skos:exactMatch EC:6.1.2.1
+property_value: skos:exactMatch RHEA:37347
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29196" xsd:anyURI
created_by: rynl
creation_date: 2024-11-13T20:22:39Z
@@ -478339,6 +495615,8 @@
xref: MetaCyc:RXN-11299
xref: RHEA:27706
is_a: GO:0016881 ! acid-amino acid ligase activity
+property_value: skos:exactMatch EC:6.3.2.35
+property_value: skos:exactMatch RHEA:27706
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29277" xsd:anyURI
created_by: rynl
creation_date: 2024-11-22T00:43:34Z
@@ -478364,7 +495642,10 @@
xref: EC:1.14.13.253
xref: RHEA:81211
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
+property_value: skos:exactMatch EC:1.14.13.253
+property_value: skos:exactMatch RHEA:81211
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29305" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-11-27T01:03:04Z
@@ -478429,7 +495710,9 @@
def: "Catalysis of the reaction: guanosine in U6 snRNA + S-adenosyl-L-methionine = H+ + N(2)-methylguanosine in U6 snRNA + S-adenosyl-L-homocysteine." [PMID:37283053]
xref: RHEA:83423
is_a: GO:0106346 ! snRNA methyltransferase activity
+property_value: skos:exactMatch RHEA:83423
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29482" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2024-12-26T18:27:41Z
@@ -478484,6 +495767,7 @@
xref: RHEA:83279
is_a: GO:0016740 ! transferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch RHEA:83279
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29535" xsd:anyURI
created_by: rynl
creation_date: 2025-01-21T20:32:11Z
@@ -478497,7 +495781,10 @@
xref: EC:3.4.13.22
xref: RHEA:20661
is_a: GO:0016805 ! dipeptidase activity
+property_value: skos:exactMatch EC:3.4.13.22
+property_value: skos:exactMatch RHEA:20661
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29199" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2025-01-22T00:55:43Z
@@ -478509,6 +495796,7 @@
synonym: "aldehyde oxidative decarbonylase activity" BROAD []
xref: RHEA:83563
is_a: GO:0016830 ! carbon-carbon lyase activity
+property_value: skos:exactMatch RHEA:83563
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28217" xsd:anyURI
created_by: rynl
creation_date: 2025-01-22T22:31:47Z
@@ -478543,6 +495831,7 @@
def: "Catalysis of the reaction: a cardiolipin + NAD+ = a diphosphatidylglycerone + NADH + H+." [PMID:26338420, RHEA:81091]
xref: RHEA:81091
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:81091
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29557" xsd:anyURI
created_by: rynl
creation_date: 2025-01-30T18:41:21Z
@@ -478554,6 +495843,7 @@
def: "Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + NAD+ = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerone) + NADH + H+." [PMID:26338420, RHEA:81099]
xref: RHEA:81099
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:81099
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29558" xsd:anyURI
created_by: rynl
creation_date: 2025-01-30T21:41:30Z
@@ -478597,9 +495887,9 @@
name: NADPH-iron-sulfur [2Fe-2S] protein oxidoreductase activity
namespace: molecular_function
def: "Catalysis of the reaction: 2 oxidized [2Fe-2S]-[protein] + NADPH = 2 reduced [2Fe-2S]-[protein] + NADP+ + H+." [RHEA:67716]
-xref: Reactome:R-HSA-2564824 "NADPH reduces NDOR1:CIAPIN1"
xref: RHEA:67716
is_a: GO:0016731 ! oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:67716
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29668" xsd:anyURI
created_by: rynl
creation_date: 2025-02-08T01:39:32Z
@@ -478625,7 +495915,9 @@
xref: RHEA:83895
is_a: GO:0008170 ! N-methyltransferase activity
is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity
+property_value: skos:exactMatch RHEA:83895
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29694" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: rynl
creation_date: 2025-03-04T08:07:33Z
@@ -478678,7 +495970,11 @@
name: de novo tRNA queuosine(34) biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of tRNA queuosine(34) from guanosine triphosphate (GTP)." [PMID:28208705]
+xref: MetaCyc:PWY-6700
+xref: MetaCyc:PWY-6703
is_a: GO:0008616 ! tRNA queuosine(34) biosynthetic process
+property_value: skos:narrowMatch MetaCyc:PWY-6700
+property_value: skos:narrowMatch MetaCyc:PWY-6703
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29892" xsd:anyURI
created_by: rynl
creation_date: 2025-03-18T04:25:52Z
@@ -478758,6 +496054,7 @@
xref: RHEA:57416
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0140096 ! catalytic activity, acting on a protein
+property_value: skos:exactMatch RHEA:57416
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30190" xsd:anyURI
created_by: rynl
creation_date: 2025-04-29T23:06:28Z
@@ -478778,6 +496075,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: acetyl-CoA + histone H1 = CoA + acetyl-histone H1." [PMID:40240600]
is_a: GO:0004402 ! histone acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30190" xsd:anyURI
created_by: rynl
@@ -478789,6 +496087,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: acetyl-CoA + histone H1 L-lysine (position 75) = CoA + histone H1 N6-acetyl-L-lysine (position 75)." [PMID:40240600]
is_a: GO:0160262 ! histone H1 acetyltransferase activity
+property_value: skos:broadMatch RHEA:21992
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30180" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30190" xsd:anyURI
created_by: rynl
@@ -478809,7 +496108,11 @@
name: O-fucosylpeptide 3-beta-glucosyltransferase activity
namespace: molecular_function
def: "Catalysis of the transfer of a alpha-D-glucose residue from UDP-alpha-D-glucose to the fucose residue of a fucosylated protein acceptor." [PMID:16899492]
+xref: RHEA:70543
+xref: RHEA:70547
is_a: GO:0035251 ! UDP-glucosyltransferase activity
+property_value: skos:narrowMatch RHEA:70543
+property_value: skos:narrowMatch RHEA:70547
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30246" xsd:anyURI
created_by: rynl
creation_date: 2025-05-13T21:17:26Z
@@ -478869,6 +496172,7 @@
is_a: GO:0008526 ! phosphatidylinositol transfer activity
is_a: GO:0140343 ! phosphatidylserine transfer activity
is_a: GO:7770011 ! lipid exchange activity
+property_value: skos:exactMatch RHEA:81667
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30291" xsd:anyURI
created_by: rynl
creation_date: 2025-05-20T21:28:18Z
@@ -479108,6 +496412,7 @@
xref: RHEA:54144
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: skos:exactMatch RHEA:54144
created_by: rynl
creation_date: 2025-07-05T00:30:16Z
@@ -479297,6 +496602,128 @@
creation_date: 2025-09-29T23:16:32Z
[Term]
+id: GO:0160308
+name: succinate dehydrogenase (FAD) activity
+namespace: molecular_function
+def: "Catalysis of the reaction: FAD + succinate + H+ = fumarate + FADH2." [RHEA:30343, WIKIPEDIA:SDHA]
+xref: RHEA:30343
+is_a: GO:0000104 ! succinate dehydrogenase activity
+property_value: skos:exactMatch RHEA:30343
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30805" xsd:anyURI
+created_by: rynl
+creation_date: 2025-10-20T18:32:39Z
+
+[Term]
+id: GO:0160309
+name: commander complex
+namespace: cellular_component
+def: "A protein complex that promotes the recycling of internalized transmembrane proteins from endosomes back to the plasma membrane. The commander complex consists of the CCC (COMMD/CCDC22/CCDC93) subcomplex and the retriever subcomplex. In human, the CCC subcomplex consists of COMMD1, COMMD2, COMMD3, COMMD4, COMMD5, COMMD6, COMMD7, COMMD8, COMMD9, COMMD10, CCDC22 and CCDC93 and the retriever complex consists of VPS26C, VPS29 and VPS35L." [PMID:28892079, PMID:37172566]
+is_a: GO:0032991 ! protein-containing complex
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31090" xsd:anyURI
+created_by: rynl
+creation_date: 2025-11-19T23:57:27Z
+
+[Term]
+id: GO:0160313
+name: endosomal intralumenal vesicle
+namespace: cellular_component
+def: "A membrane-bounded vesicle that is located within the lumen of an endosome." [PMID:21878991, PMID:31854087]
+synonym: "ILV" EXACT []
+is_a: GO:0031410 ! cytoplasmic vesicle
+intersection_of: GO:0097708 ! intracellular vesicle
+intersection_of: part_of GO:0005768 ! endosome
+relationship: part_of GO:0005768 ! endosome
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31158" xsd:anyURI
+created_by: rynl
+creation_date: 2025-12-04T17:58:06Z
+
+[Term]
+id: GO:0160314
+name: endosomal intralumenal vesicle membrane
+namespace: cellular_component
+def: "The lipid bilayer surrounding an intraluminal vesicle within an endososome." [PMID:31854087, PMID:38706230]
+synonym: "endosome ILV membrane" EXACT []
+synonym: "endosome internal vesicle membrane" EXACT []
+is_a: GO:0030659 ! cytoplasmic vesicle membrane
+is_a: GO:0098588 ! bounding membrane of organelle
+relationship: part_of GO:0160313 ! endosomal intralumenal vesicle
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31159" xsd:anyURI
+created_by: rynl
+creation_date: 2025-12-08T16:52:03Z
+
+[Term]
+id: GO:0160315
+name: endosomal intralumenal vesicle lumen
+namespace: cellular_component
+def: "The volume enclosed by the membrane of an intraluminal vesicle within an endosome." [PMID:31854087, PMID:38706230]
+synonym: "endosome ILV lumen" EXACT []
+synonym: "endosome internal vesicle lumen" EXACT []
+is_a: GO:0070013 ! intracellular organelle lumen
+intersection_of: GO:0031974 ! membrane-enclosed lumen
+intersection_of: part_of GO:0160313 ! endosomal intralumenal vesicle
+relationship: part_of GO:0160313 ! endosomal intralumenal vesicle
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31159" xsd:anyURI
+created_by: rynl
+creation_date: 2025-12-08T17:33:35Z
+
+[Term]
+id: GO:0160316
+name: endolysosomal intralumenal vesicle
+namespace: cellular_component
+def: "A membrane-bounded vesicle that is located within the lumen of an endolysosome." [PMID:31854087, PMID:38706230]
+synonym: "endolysosomal ILV" EXACT []
+is_a: GO:0160313 ! endosomal intralumenal vesicle
+intersection_of: GO:0097708 ! intracellular vesicle
+intersection_of: part_of GO:0036019 ! endolysosome
+relationship: part_of GO:0036019 ! endolysosome
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31158" xsd:anyURI
+created_by: rynl
+creation_date: 2025-12-24T00:02:56Z
+
+[Term]
+id: GO:0160317
+name: endolysosomal intralumenal vesicle membrane
+namespace: cellular_component
+def: "The lipid bilayer surrounding an intraluminal vesicle within an endolysosome." [PMID:31854087, PMID:38706230]
+synonym: "endolysosome ILV membrane" EXACT []
+synonym: "endolysosome internal vesicle membrane" EXACT []
+is_a: GO:0160314 ! endosomal intralumenal vesicle membrane
+relationship: part_of GO:0160316 ! endolysosomal intralumenal vesicle
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31159" xsd:anyURI
+created_by: rynl
+creation_date: 2025-12-24T00:06:07Z
+
+[Term]
+id: GO:0160318
+name: endolysosomal intralumenal vesicle lumen
+namespace: cellular_component
+def: "The volume enclosed by the membrane of an intraluminal vesicle within an endolysosome." [PMID:31854087, PMID:38706230]
+synonym: "endolysosome ILV lumen" EXACT []
+synonym: "endolysosome internal vesicle lumen" EXACT []
+is_a: GO:0005775 ! vacuolar lumen
+is_a: GO:0160315 ! endosomal intralumenal vesicle lumen
+intersection_of: GO:0031974 ! membrane-enclosed lumen
+intersection_of: part_of GO:0160316 ! endolysosomal intralumenal vesicle
+relationship: part_of GO:0160316 ! endolysosomal intralumenal vesicle
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31160" xsd:anyURI
+created_by: rynl
+creation_date: 2025-12-24T00:18:06Z
+
+[Term]
+id: GO:0160319
+name: lipoyl-dependent peroxiredoxin activity
+namespace: molecular_function
+def: "Catalysis of the reaction: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + a hydroperoxide = N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + an alcohol + H2O." [EC:1.11.1.28, RHEA:62636]
+xref: EC:1.11.1.28
+xref: RHEA:62636
+is_a: GO:0004601 ! peroxidase activity
+property_value: skos:exactMatch EC:1.11.1.28
+property_value: skos:exactMatch RHEA:62636
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31239" xsd:anyURI
+created_by: rynl
+creation_date: 2025-12-29T00:52:44Z
+
+[Term]
id: GO:0170001
name: ergothioneine transmembrane transporter activity
namespace: molecular_function
@@ -479364,8 +496791,6 @@
name: endoplasmic reticulum-lipid droplet tether activity
namespace: molecular_function
def: "The binding activity of a molecule that brings together a lipid droplet with an endoplasmic reticulum membrane, via membrane lipid binding, to establish membrane contact sites and mediate exchange and communication." [PMID:35389430]
-xref: Reactome:R-HSA-8857686 "FITM2 binds TAGs"
-xref: Reactome:R-HSA-9942190 "FITM1 binds TAGs"
is_a: GO:0043495 ! protein-membrane adaptor activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25428" xsd:anyURI
created_by: ew
@@ -479422,6 +496847,7 @@
def: "Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone H3 position 18] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[histone H3] + nicotinamide." [PMID:34927582]
comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
is_a: GO:0160012 ! histone decrotonylase activity, NAD-dependent
+property_value: skos:broadMatch RHEA:69332
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24466" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: ew
@@ -479803,7 +497229,13 @@
synonym: "cholesterol 7,8-dehydrogenase" EXACT []
xref: EC:1.14.19.21
xref: MetaCyc:RXN-16379
+xref: RHEA:45024
+xref: RHEA:51644
is_a: GO:0070704 ! sterol desaturase activity
+property_value: skos:exactMatch EC:1.14.19.21
+property_value: skos:exactMatch MetaCyc:RXN-16379
+property_value: skos:narrowMatch RHEA:45024
+property_value: skos:narrowMatch RHEA:51644
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27381" xsd:anyURI
created_by: ew
creation_date: 2024-03-26T16:57:18Z
@@ -479815,7 +497247,16 @@
def: "Catalysis of the joining of an RNA with 3'-phosphate or 2',3'-cyclic-phosphate ends to an RNA with 5'-hydroxy ends according to either (i) a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP; or (ii) a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP + H2O = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP + H+." [EC:6.5.1.8, PMID:21311021]
synonym: "3'-phosphate/5'-hydroxy nucleic acid ligase activity" EXACT []
xref: EC:6.5.1.8
+xref: MetaCyc:RXN-17905
+xref: MetaCyc:RXN0-6566
+xref: RHEA:68076
+xref: RHEA:68080
is_a: GO:0008452 ! RNA ligase activity
+property_value: skos:exactMatch EC:6.5.1.8
+property_value: skos:narrowMatch MetaCyc:RXN-17905
+property_value: skos:narrowMatch MetaCyc:RXN0-6566
+property_value: skos:narrowMatch RHEA:68076
+property_value: skos:narrowMatch RHEA:68080
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27418" xsd:anyURI
created_by: ew
creation_date: 2024-03-26T23:34:04Z
@@ -479899,6 +497340,7 @@
synonym: "arginine biosynthesis, N-acetylated pathway" EXACT []
xref: MetaCyc:PWY-5154
is_a: GO:0006526 ! L-arginine biosynthetic process
+property_value: skos:exactMatch MetaCyc:PWY-5154
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29602" xsd:anyURI
created_by: ew
creation_date: 2025-03-14T17:04:09Z
@@ -480006,7 +497448,9 @@
is_a: GO:0015211 ! purine nucleoside transmembrane transporter activity
is_a: GO:0015297 ! antiporter activity
is_a: GO:0072349 ! modified amino acid transmembrane transporter activity
+property_value: skos:exactMatch RHEA:75479
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24887" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: vw
creation_date: 2023-02-10T13:06:12Z
@@ -480017,6 +497461,7 @@
def: "Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-tyrosine (consensus YSPTSPS)(position 1) + H2O = RNA polymerase II large subunit + phosphate." [PMID:22622228]
synonym: "RNA polymerase II C-terminal domain Y1 phosphatase activity" EXACT []
is_a: GO:0008420 ! RNA polymerase II CTD heptapeptide repeat phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.16
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24910" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: vw
@@ -480029,6 +497474,7 @@
def: "Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-threonine (consensus YSPTSPS)(position 4) + H2O = RNA polymerase II large subunit + phosphate." [PMID:22622228]
synonym: "RNA polymerase II C-terminal domain T4 phosphatase activity" EXACT []
is_a: GO:0008420 ! RNA polymerase II CTD heptapeptide repeat phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.16
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24910" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: vw
@@ -480041,6 +497487,7 @@
def: "Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 2) + H2O = RNA polymerase II large subunit + phosphate." [PMID:22622228]
synonym: "RNA polymerase II C-terminal domain S2 phosphatase activity" EXACT []
is_a: GO:0008420 ! RNA polymerase II CTD heptapeptide repeat phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.16
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24910" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: vw
@@ -480053,6 +497500,7 @@
def: "Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 5) + H2O = RNA polymerase II large subunit + phosphate." [PMID:22622228]
synonym: "RNA polymerase II C-terminal domain S5 phosphatase activity" EXACT []
is_a: GO:0008420 ! RNA polymerase II CTD heptapeptide repeat phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.16
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24910" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: vw
@@ -480065,6 +497513,7 @@
def: "Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 7) + H2O = RNA polymerase II large subunit + phosphate." [PMID:22622228]
synonym: "RNA polymerase II C-terminal domain S7 phosphatase activity" EXACT []
is_a: GO:0008420 ! RNA polymerase II CTD heptapeptide repeat phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.16
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24910" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: vw
@@ -480079,9 +497528,17 @@
synonym: "neutral L-amino acid:dibasic L-amino acid antiporter activity" EXACT []
synonym: "neutral L-amino acid:positively-charged polar L-amino acid antiporter activity" EXACT []
synonym: "system b(0,+)-type activity" RELATED []
+xref: RHEA:71059
+xref: RHEA:71067
+xref: RHEA:71071
+xref: RHEA:71075
is_a: GO:0015174 ! basic amino acid transmembrane transporter activity
is_a: GO:0015175 ! neutral L-amino acid transmembrane transporter activity
is_a: GO:0015297 ! antiporter activity
+property_value: skos:narrowMatch RHEA:71059
+property_value: skos:narrowMatch RHEA:71067
+property_value: skos:narrowMatch RHEA:71071
+property_value: skos:narrowMatch RHEA:71075
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24497" xsd:anyURI
created_by: vw
creation_date: 2023-04-06T09:22:30Z
@@ -480128,6 +497585,7 @@
namespace: molecular_function
def: "Catalysis of the movement of a lysophosphatidylserine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP." [PMID:34645814]
is_a: GO:0140333 ! glycerophospholipid flippase activity
+property_value: skos:broadMatch RHEA:66132
created_by: vw
creation_date: 2023-02-23T14:32:13Z
@@ -480187,10 +497645,11 @@
id: GO:0180019
name: Knl1/Spc105 complex
namespace: cellular_component
-def: "A kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans and yeast respectively, it consists of KNL1/Spc105p and ZWINT/Kre28p." [PMID:27881301]
+def: "A kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It is involved in kinetochore-microtubule binding, recruiting microtubule binding outer kinetochore subunits. It is essential for kinetochore binding by components of the spindle assembly checkpoint. In humans and budding yeast respectively, it consists of KNL1/Spc105p and ZWINT/Kre28p." [PMID:14565975, PMID:19893618]
is_a: GO:0032991 ! protein-containing complex
relationship: part_of GO:0000940 ! outer kinetochore
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25544" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31052" xsd:anyURI
created_by: vw
creation_date: 2023-06-16T09:53:26Z
@@ -480212,7 +497671,9 @@
def: "Catalysis of the reaction: S-adenosyl-L-methionine + U6 snRNA = S-adenosyl-L-homocysteine + U6 containing a 3'-terminal 2'-O-methylnucleotide + H+." [PMID:37403782, RHEA:63088]
xref: RHEA:63088
is_a: GO:0090486 ! small RNA 2'-O-methyltransferase activity
+property_value: skos:exactMatch RHEA:63088
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25706" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: vw
creation_date: 2023-07-14T13:19:39Z
@@ -480337,6 +497798,7 @@
synonym: "histone H4K5 deacetylase activity" BROAD []
is_a: GO:0141051 ! histone H4K deacetylase activity
is_a: GO:0141221 ! histone deacetylase activity, hydrolytic mechanism
+property_value: skos:broadMatch EC:3.5.1.98
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27036" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29468" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -480352,6 +497814,7 @@
synonym: "histone H4K48 deacetylase activity" BROAD []
is_a: GO:0141051 ! histone H4K deacetylase activity
is_a: GO:0141221 ! histone deacetylase activity, hydrolytic mechanism
+property_value: skos:broadMatch EC:3.5.1.98
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27036" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29468" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
@@ -480453,6 +497916,7 @@
xref: RHEA:60500
is_a: GO:0004376 ! GPI mannosyltransferase activity
is_a: GO:0051751 ! alpha-1,4-mannosyltransferase activity
+property_value: skos:exactMatch RHEA:60500
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30326" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30693" xsd:anyURI
created_by: vw
@@ -481883,7 +499347,6 @@
synonym: "negative regulation of ceramide biosynthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of ceramide formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of ceramide synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0090155 ! negative regulation of sphingolipid biosynthetic process
is_a: GO:2000303 ! regulation of ceramide biosynthetic process
intersection_of: GO:0065007 ! biological regulation
@@ -483679,7 +501142,7 @@
synonym: "negative regulation of phosphatidylcholine 2-acylhydrolase activity" EXACT [GOC:TermGenie]
synonym: "negative regulation of phospholipase A" RELATED [GOC:TermGenie]
synonym: "negative regulation of secreted phospholipase A2 activity" NARROW [GOC:TermGenie]
-property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22455" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28033" xsd:anyURI
is_obsolete: true
created_by: rph
creation_date: 2012-03-01T09:18:24Z
@@ -484869,7 +502332,6 @@
synonym: "regulation of penicillin biosynthesis" EXACT [GOC:TermGenie]
synonym: "regulation of penicillin formation" EXACT [GOC:TermGenie]
synonym: "regulation of penicillin synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0042762 ! regulation of sulfur metabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process
@@ -484908,7 +502370,6 @@
synonym: "negative regulation of penicillin biosynthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of penicillin formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of penicillin synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
is_a: GO:1900196 ! regulation of penicillin biosynthetic process
is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process
@@ -485337,9 +502798,10 @@
[Term]
id: GO:1900216
-name: positive regulation of apoptotic process involved in metanephric collecting duct development
+name: obsolete positive regulation of apoptotic process involved in metanephric collecting duct development
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "activation of apoptotic process involved in metanephric collecting duct development" NARROW [GOC:TermGenie]
@@ -485384,11 +502846,10 @@
synonym: "upregulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "upregulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie]
synonym: "upregulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie]
-is_a: GO:1900214 ! regulation of apoptotic process involved in metanephric collecting duct development
-is_a: GO:1904747 ! positive regulation of apoptotic process involved in development
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development
-relationship: positively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0072205
+consider: GO:1904747
created_by: yaf
creation_date: 2012-03-22T10:53:39Z
@@ -485471,9 +502932,10 @@
[Term]
id: GO:1900219
-name: positive regulation of apoptotic process involved in metanephric nephron tubule development
+name: obsolete positive regulation of apoptotic process involved in metanephric nephron tubule development
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "activation of apoptotic process involved in metanephric nephron tubule development" NARROW [GOC:TermGenie]
@@ -485518,25 +502980,25 @@
synonym: "upregulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "upregulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie]
synonym: "upregulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie]
-is_a: GO:1900217 ! regulation of apoptotic process involved in metanephric nephron tubule development
-is_a: GO:1904747 ! positive regulation of apoptotic process involved in development
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development
-relationship: positively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0072234
+consider: GO:1904747
created_by: yaf
creation_date: 2012-03-22T10:54:09Z
[Term]
id: GO:1900220
-name: semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis
+name: obsolete semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis
namespace: biological_process
-def: "Any semaphorin-plexin signaling pathway that contributes to bone trabecula morphogenesis." [GOC:BHF, GOC:TermGenie]
+def: "OBSOLETE. Any semaphorin-plexin signaling pathway that contributes to bone trabecula morphogenesis." [GOC:BHF, GOC:TermGenie]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "semaphorin-plexin signaling pathway of bone trabecula morphogenesis" EXACT [GOC:TermGenie]
synonym: "semaphorin-plexin signalling pathway of bone trabecula morphogenesis" EXACT [GOC:TermGenie]
-is_a: GO:0071526 ! semaphorin-plexin signaling pathway
-intersection_of: GO:0071526 ! semaphorin-plexin signaling pathway
-intersection_of: part_of GO:0061430 ! bone trabecula morphogenesis
-relationship: part_of GO:0061430 ! bone trabecula morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0061430
+consider: GO:0071526
created_by: vk
creation_date: 2012-03-22T01:13:56Z
@@ -490163,9 +507625,10 @@
[Term]
id: GO:1900447
-name: regulation of cell morphogenesis involved in phenotypic switching
+name: obsolete regulation of cell morphogenesis involved in phenotypic switching
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of cell morphogenesis contributing a phenotypic switch. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells, such as the opaque cells of C. albicans, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:di, GOC:TermGenie]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of cell morphogenesis contributing a phenotypic switch. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells, such as the opaque cells of C. albicans, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:di, GOC:TermGenie]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "negative regulation of cell shape and cell size of phenotypic dimorphism" RELATED [GOC:TermGenie]
synonym: "negative regulation of cell shape and cell size of phenotypic switching" RELATED [GOC:TermGenie]
synonym: "positive regulation of cell shape and cell size of phenotypic dimorphism" RELATED [GOC:TermGenie]
@@ -490174,10 +507637,10 @@
synonym: "regulation of cell morphogenesis of phenotypic switching" EXACT [GOC:TermGenie]
synonym: "regulation of cell shape and cell size of phenotypic dimorphism" RELATED [GOC:TermGenie]
synonym: "regulation of cell shape and cell size of phenotypic switching" RELATED [GOC:TermGenie]
-is_a: GO:0022604 ! regulation of cell morphogenesis
-intersection_of: GO:0022604 ! regulation of cell morphogenesis
-intersection_of: part_of GO:0036166 ! phenotypic switching
-relationship: part_of GO:0036166 ! phenotypic switching
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0022604
+consider: GO:0036166
created_by: di
creation_date: 2012-04-27T02:43:32Z
@@ -490887,7 +508350,6 @@
synonym: "upregulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway" EXACT [GOC:TermGenie]
synonym: "upregulation of isopentenyl diphosphate formation, mevalonate pathway" EXACT [GOC:TermGenie]
synonym: "upregulation of isopentenyl diphosphate synthesis, mevalonate pathway" EXACT [GOC:TermGenie]
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
is_a: GO:0071073 ! positive regulation of phospholipid biosynthetic process
is_a: GO:2001210 ! regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway
@@ -491089,7 +508551,6 @@
synonym: "inhibition of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie]
synonym: "inhibition of butyryl-CoA biosynthetic process from acetyl-CoA" NARROW [GOC:TermGenie]
synonym: "negative regulation of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie]
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0045717 ! negative regulation of fatty acid biosynthetic process
is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process
is_a: GO:0045936 ! negative regulation of phosphate metabolic process
@@ -491114,7 +508575,6 @@
synonym: "up-regulation of butyryl-CoA biosynthetic process from acetyl-CoA" EXACT [GOC:TermGenie]
synonym: "upregulation of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie]
synonym: "upregulation of butyryl-CoA biosynthetic process from acetyl-CoA" EXACT [GOC:TermGenie]
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0045723 ! positive regulation of fatty acid biosynthetic process
is_a: GO:0045937 ! positive regulation of phosphate metabolic process
is_a: GO:1900494 ! regulation of butyryl-CoA biosynthetic process from acetyl-CoA
@@ -491132,7 +508592,6 @@
synonym: "regulation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie]
is_a: GO:0019217 ! regulation of fatty acid metabolic process
is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0042762 ! regulation of sulfur metabolic process
is_a: GO:0046890 ! regulation of lipid biosynthetic process
is_a: GO:0050994 ! regulation of lipid catabolic process
@@ -491158,7 +508617,6 @@
synonym: "inhibition of butyryl-CoA catabolic process to butanol" NARROW [GOC:TermGenie]
synonym: "inhibition of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie]
synonym: "negative regulation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie]
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0045922 ! negative regulation of fatty acid metabolic process
is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process
is_a: GO:0045936 ! negative regulation of phosphate metabolic process
@@ -491186,7 +508644,6 @@
synonym: "up-regulation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie]
synonym: "upregulation of butyryl-CoA catabolic process to butanol" EXACT [GOC:TermGenie]
synonym: "upregulation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie]
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0045923 ! positive regulation of fatty acid metabolic process
is_a: GO:0045937 ! positive regulation of phosphate metabolic process
is_a: GO:0046889 ! positive regulation of lipid biosynthetic process
@@ -491206,7 +508663,6 @@
def: "Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butyrate." [GOC:mengo_curators, GOC:TermGenie]
synonym: "regulation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie]
is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0042304 ! regulation of fatty acid biosynthetic process
is_a: GO:0042762 ! regulation of sulfur metabolic process
is_a: GO:0050994 ! regulation of lipid catabolic process
@@ -491231,7 +508687,6 @@
synonym: "inhibition of butyryl-CoA catabolic process to butyrate" NARROW [GOC:TermGenie]
synonym: "inhibition of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie]
synonym: "negative regulation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie]
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0045717 ! negative regulation of fatty acid biosynthetic process
is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process
is_a: GO:0045936 ! negative regulation of phosphate metabolic process
@@ -491257,7 +508712,6 @@
synonym: "up-regulation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie]
synonym: "upregulation of butyryl-CoA catabolic process to butyrate" EXACT [GOC:TermGenie]
synonym: "upregulation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie]
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0045723 ! positive regulation of fatty acid biosynthetic process
is_a: GO:0045937 ! positive regulation of phosphate metabolic process
is_a: GO:0050996 ! positive regulation of lipid catabolic process
@@ -491545,8 +508999,8 @@
is_a: GO:0043465 ! regulation of fermentation
is_a: GO:0043469 ! regulation of D-xylose catabolic process
intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0044577 ! D-xylose catabolic process to ethanol
-relationship: regulates GO:0044577 ! D-xylose catabolic process to ethanol
+intersection_of: regulates GO:0044577 ! D-xylose fermentation
+relationship: regulates GO:0044577 ! D-xylose fermentation
created_by: tt
creation_date: 2012-05-02T04:09:07Z
@@ -491570,8 +509024,8 @@
is_a: GO:1900515 ! regulation of xylose catabolic process to ethanol
is_a: GO:1901003 ! negative regulation of fermentation
intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0044577 ! D-xylose catabolic process to ethanol
-relationship: negatively_regulates GO:0044577 ! D-xylose catabolic process to ethanol
+intersection_of: negatively_regulates GO:0044577 ! D-xylose fermentation
+relationship: negatively_regulates GO:0044577 ! D-xylose fermentation
created_by: tt
creation_date: 2012-05-02T04:09:17Z
@@ -491594,8 +509048,8 @@
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
is_a: GO:1900515 ! regulation of xylose catabolic process to ethanol
intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0044577 ! D-xylose catabolic process to ethanol
-relationship: positively_regulates GO:0044577 ! D-xylose catabolic process to ethanol
+intersection_of: positively_regulates GO:0044577 ! D-xylose fermentation
+relationship: positively_regulates GO:0044577 ! D-xylose fermentation
created_by: tt
creation_date: 2012-05-02T04:09:26Z
@@ -492862,7 +510316,6 @@
synonym: "tensidol A catabolism" EXACT [GOC:TermGenie]
synonym: "tensidol A degradation" EXACT [GOC:TermGenie]
is_a: GO:0042182 ! ketone catabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0090487 ! secondary metabolite catabolic process
created_by: di
creation_date: 2012-05-15T06:58:09Z
@@ -492877,7 +510330,6 @@
synonym: "tensidol A formation" EXACT [GOC:TermGenie]
synonym: "tensidol A synthesis" EXACT [GOC:TermGenie]
is_a: GO:0042181 ! ketone biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0044550 ! secondary metabolite biosynthetic process
created_by: di
creation_date: 2012-05-15T06:58:16Z
@@ -492903,7 +510355,6 @@
synonym: "tensidol B catabolism" EXACT [GOC:TermGenie]
synonym: "tensidol B degradation" EXACT [GOC:TermGenie]
is_a: GO:0042182 ! ketone catabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0046395 ! carboxylic acid catabolic process
is_a: GO:0090487 ! secondary metabolite catabolic process
created_by: di
@@ -492919,7 +510370,6 @@
synonym: "tensidol B formation" EXACT [GOC:TermGenie]
synonym: "tensidol B synthesis" EXACT [GOC:TermGenie]
is_a: GO:0042181 ! ketone biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0044550 ! secondary metabolite biosynthetic process
is_a: GO:0046394 ! carboxylic acid biosynthetic process
created_by: di
@@ -494010,7 +511460,6 @@
synonym: "regulation of emericellamide biosynthesis" EXACT [GOC:TermGenie]
synonym: "regulation of emericellamide formation" EXACT [GOC:TermGenie]
synonym: "regulation of emericellamide synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0046890 ! regulation of lipid biosynthetic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process
@@ -494049,7 +511498,6 @@
synonym: "negative regulation of emericellamide biosynthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of emericellamide formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of emericellamide synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0051055 ! negative regulation of lipid biosynthetic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process
@@ -494089,7 +511537,6 @@
synonym: "upregulation of emericellamide biosynthetic process" EXACT [GOC:TermGenie]
synonym: "upregulation of emericellamide formation" EXACT [GOC:TermGenie]
synonym: "upregulation of emericellamide synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0046889 ! positive regulation of lipid biosynthetic process
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process
@@ -494916,7 +512363,6 @@
synonym: "regulation of gliotoxin biosynthesis" EXACT [GOC:TermGenie]
synonym: "regulation of gliotoxin formation" EXACT [GOC:TermGenie]
synonym: "regulation of gliotoxin synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0042762 ! regulation of sulfur metabolic process
is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process
intersection_of: GO:0065007 ! biological regulation
@@ -494954,7 +512400,6 @@
synonym: "negative regulation of gliotoxin biosynthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of gliotoxin formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of gliotoxin synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process
is_a: GO:1900689 ! regulation of gliotoxin biosynthetic process
intersection_of: GO:0065007 ! biological regulation
@@ -494992,7 +512437,6 @@
synonym: "upregulation of gliotoxin biosynthetic process" EXACT [GOC:TermGenie]
synonym: "upregulation of gliotoxin formation" EXACT [GOC:TermGenie]
synonym: "upregulation of gliotoxin synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process
is_a: GO:1900689 ! regulation of gliotoxin biosynthetic process
intersection_of: GO:0065007 ! biological regulation
@@ -495509,7 +512953,6 @@
synonym: "regulation of tensidol A formation" EXACT [GOC:TermGenie]
synonym: "regulation of tensidol A synthesis" EXACT [GOC:TermGenie]
is_a: GO:0010566 ! regulation of ketone biosynthetic process
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1900605 ! tensidol A biosynthetic process
@@ -495546,7 +512989,6 @@
synonym: "negative regulation of tensidol A biosynthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of tensidol A formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of tensidol A synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process
is_a: GO:1900707 ! regulation of tensidol A biosynthetic process
@@ -495585,7 +513027,6 @@
synonym: "upregulation of tensidol A biosynthetic process" EXACT [GOC:TermGenie]
synonym: "upregulation of tensidol A formation" EXACT [GOC:TermGenie]
synonym: "upregulation of tensidol A synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process
is_a: GO:1900707 ! regulation of tensidol A biosynthetic process
@@ -495605,7 +513046,6 @@
synonym: "regulation of tensidol B formation" EXACT [GOC:TermGenie]
synonym: "regulation of tensidol B synthesis" EXACT [GOC:TermGenie]
is_a: GO:0010566 ! regulation of ketone biosynthetic process
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1900608 ! tensidol B biosynthetic process
@@ -495642,7 +513082,6 @@
synonym: "negative regulation of tensidol B biosynthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of tensidol B formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of tensidol B synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process
is_a: GO:1900710 ! regulation of tensidol B biosynthetic process
@@ -495681,7 +513120,6 @@
synonym: "upregulation of tensidol B biosynthetic process" EXACT [GOC:TermGenie]
synonym: "upregulation of tensidol B formation" EXACT [GOC:TermGenie]
synonym: "upregulation of tensidol B synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process
is_a: GO:1900710 ! regulation of tensidol B biosynthetic process
@@ -496049,13 +513487,14 @@
[Term]
id: GO:1900728
-name: cardiac neural crest cell delamination involved in outflow tract morphogenesis
+name: obsolete cardiac neural crest cell delamination involved in outflow tract morphogenesis
namespace: biological_process
-def: "Any cardiac neural crest cell delamination that is involved in outflow tract morphogenesis." [GOC:hjd, GOC:TermGenie, PMID:18539270]
-is_a: GO:0036036 ! cardiac neural crest cell delamination
-intersection_of: GO:0036036 ! cardiac neural crest cell delamination
-intersection_of: part_of GO:0003151 ! outflow tract morphogenesis
-relationship: part_of GO:0003151 ! outflow tract morphogenesis
+def: "OBSOLETE. Any cardiac neural crest cell delamination that is involved in outflow tract morphogenesis." [GOC:hjd, GOC:TermGenie, PMID:18539270]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003151
+consider: GO:0036036
created_by: bf
creation_date: 2012-05-25T09:50:24Z
@@ -496616,7 +514055,7 @@
synonym: "Oligopeptid binding" RELATED [GOC:TermGenie]
synonym: "oligopeptides binding" EXACT [GOC:TermGenie]
synonym: "oligopeptido binding" RELATED [GOC:TermGenie]
-is_a: GO:0033218 ! amide binding
+is_a: GO:0005488 ! binding
created_by: jl
creation_date: 2012-05-29T02:13:31Z
@@ -497475,7 +514914,6 @@
synonym: "tryptophan-proline diketopiperazine synthesis" RELATED [GOC:TermGenie]
is_a: GO:0035835 ! indole alkaloid biosynthetic process
is_a: GO:0042435 ! indole-containing compound biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23885" xsd:anyURI
created_by: di
creation_date: 2012-06-04T09:52:48Z
@@ -497652,7 +515090,6 @@
synonym: "ochratoxin A catabolism" EXACT [GOC:TermGenie]
synonym: "ochratoxin A degradation" EXACT [GOC:TermGenie]
is_a: GO:0042219 ! modified amino acid catabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0072329 ! monocarboxylic acid catabolic process
is_a: GO:0090345 ! organohalogen metabolic process
is_a: GO:0090487 ! secondary metabolite catabolic process
@@ -497669,7 +515106,6 @@
synonym: "Ochratoxin A formation" EXACT [GOC:TermGenie]
synonym: "Ochratoxin A synthesis" EXACT [GOC:TermGenie]
is_a: GO:0042398 ! modified amino acid biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0044550 ! secondary metabolite biosynthetic process
is_a: GO:0072330 ! monocarboxylic acid biosynthetic process
is_a: GO:0090345 ! organohalogen metabolic process
@@ -498198,7 +515634,6 @@
synonym: "regulation of Pseurotin formation" RELATED [GOC:TermGenie]
synonym: "regulation of Pseurotin synthesis" RELATED [GOC:TermGenie]
is_a: GO:0009889 ! regulation of biosynthetic process
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1900790 ! pseurotin A biosynthetic process
@@ -498215,7 +515650,6 @@
synonym: "down-regulation of pseurotin A biosynthetic process" EXACT [GOC:TermGenie]
synonym: "downregulation of pseurotin A biosynthetic process" EXACT [GOC:TermGenie]
is_a: GO:0009890 ! negative regulation of biosynthetic process
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
is_a: GO:1900849 ! regulation of pseurotin A biosynthetic process
intersection_of: GO:0065007 ! biological regulation
@@ -498233,7 +515667,6 @@
synonym: "up-regulation of pseurotin A biosynthetic process" EXACT [GOC:TermGenie]
synonym: "upregulation of pseurotin A biosynthetic process" EXACT [GOC:TermGenie]
is_a: GO:0009891 ! positive regulation of biosynthetic process
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
is_a: GO:1900849 ! regulation of pseurotin A biosynthetic process
intersection_of: GO:0065007 ! biological regulation
@@ -501648,13 +519081,14 @@
[Term]
id: GO:1901025
-name: ripoptosome assembly involved in extrinsic apoptotic signaling pathway
+name: obsolete ripoptosome assembly involved in extrinsic apoptotic signaling pathway
namespace: biological_process
-def: "The aggregation, arrangement and bonding together of ripoptosome components leading to apoptosis via the extrinsic apoptotic signaling pathway." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:22274400]
-is_a: GO:0097343 ! ripoptosome assembly
-intersection_of: GO:0097343 ! ripoptosome assembly
-intersection_of: part_of GO:0097191 ! extrinsic apoptotic signaling pathway
-relationship: part_of GO:0097191 ! extrinsic apoptotic signaling pathway
+def: "OBSOLETE. The aggregation, arrangement and bonding together of ripoptosome components leading to apoptosis via the extrinsic apoptotic signaling pathway." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:22274400]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0097191
+consider: GO:0097343
created_by: pr
creation_date: 2012-06-19T08:49:33Z
@@ -502740,11 +520174,13 @@
[Term]
id: GO:1901089
-name: acetate ester metabolic process involved in fermentation
+name: obsolete acetate ester metabolic process involved in fermentation
namespace: biological_process
-def: "Any acetate ester metabolic process that is involved in fermentation." [GOC:sgd_curators, GOC:TermGenie]
+def: "OBSOLETE. Any acetate ester metabolic process that is involved in fermentation." [GOC:sgd_curators, GOC:TermGenie]
+comment: The reason for obsoletion is that the term is not clearly defined.
synonym: "acetate ester metabolic process during fermentation" EXACT [GOC:sgd_curators]
-is_a: GO:0006113 ! fermentation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31215" xsd:anyURI
+is_obsolete: true
created_by: rb
creation_date: 2012-07-05T11:47:17Z
@@ -503101,7 +520537,7 @@
synonym: "gramicidin S biosynthesis" EXACT [GOC:TermGenie]
synonym: "gramicidin S formation" EXACT [GOC:TermGenie]
synonym: "gramicidin S synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0043604 ! amide biosynthetic process
+is_a: GO:0009058 ! biosynthetic process
created_by: yaf
creation_date: 2012-07-11T02:31:00Z
@@ -503361,7 +520797,6 @@
synonym: "bacitracin A catabolism" EXACT [GOC:TermGenie]
synonym: "bacitracin A degradation" EXACT [GOC:TermGenie]
is_a: GO:0009056 ! catabolic process
-is_a: GO:0043603 ! amide metabolic process
created_by: yaf
creation_date: 2012-07-11T03:16:20Z
@@ -503374,7 +520809,7 @@
synonym: "bacitracin A biosynthesis" EXACT [GOC:TermGenie]
synonym: "bacitracin A formation" EXACT [GOC:TermGenie]
synonym: "bacitracin A synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0043604 ! amide biosynthetic process
+is_a: GO:0009058 ! biosynthetic process
created_by: yaf
creation_date: 2012-07-11T03:16:27Z
@@ -504450,9 +521885,10 @@
[Term]
id: GO:1901196
-name: positive regulation of calcium-mediated signaling involved in cellular response to salt stress
+name: obsolete positive regulation of calcium-mediated signaling involved in cellular response to salt stress
namespace: biological_process
-def: "Any positive regulation of calcium-mediated signaling that is involved in cellular response to salt stress." [GOC:TermGenie]
+def: "OBSOLETE. Any positive regulation of calcium-mediated signaling that is involved in cellular response to salt stress." [GOC:TermGenie]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of calcium-mediated signaling involved in cellular response to ionic osmotic stress" NARROW [GOC:TermGenie]
synonym: "activation of calcium-mediated signaling involved in cellular response to salt stress" NARROW [GOC:TermGenie]
synonym: "activation of calcium-mediated signaling involved in cellular salinity response" NARROW [GOC:TermGenie]
@@ -504473,18 +521909,19 @@
synonym: "upregulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress" EXACT [GOC:TermGenie]
synonym: "upregulation of calcium-mediated signaling involved in cellular response to salt stress" EXACT [GOC:TermGenie]
synonym: "upregulation of calcium-mediated signaling involved in cellular salinity response" EXACT [GOC:TermGenie]
-is_a: GO:0050850 ! positive regulation of calcium-mediated signaling
-intersection_of: GO:0050850 ! positive regulation of calcium-mediated signaling
-intersection_of: part_of GO:0071472 ! cellular response to salt stress
-relationship: part_of GO:0071472 ! cellular response to salt stress
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0050850
+consider: GO:0071472
created_by: al
creation_date: 2012-07-27T10:52:56Z
[Term]
id: GO:1901197
-name: positive regulation of calcium-mediated signaling involved in cellular response to calcium ion
+name: obsolete positive regulation of calcium-mediated signaling involved in cellular response to calcium ion
namespace: biological_process
-def: "Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion." [GOC:TermGenie]
+def: "OBSOLETE. Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion." [GOC:TermGenie]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of calcium-mediated signaling involved in cellular response to Ca2+ ion" NARROW [GOC:TermGenie]
synonym: "activation of calcium-mediated signaling involved in cellular response to calcium ion" NARROW [GOC:TermGenie]
synonym: "positive regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie]
@@ -504498,51 +521935,54 @@
synonym: "up-regulation of calcium-mediated signaling involved in response to calcium ion" EXACT [GOC:TermGenie]
synonym: "upregulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie]
synonym: "upregulation of calcium-mediated signaling involved in cellular response to calcium ion" EXACT [GOC:TermGenie]
-is_a: GO:0050850 ! positive regulation of calcium-mediated signaling
-intersection_of: GO:0050850 ! positive regulation of calcium-mediated signaling
-intersection_of: part_of GO:0071277 ! cellular response to calcium ion
-relationship: part_of GO:0071277 ! cellular response to calcium ion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0050850
+consider: GO:0071277
created_by: al
creation_date: 2012-07-27T10:57:56Z
[Term]
id: GO:1901198
-name: positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion
+name: obsolete positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion
namespace: biological_process
-def: "Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to calcium ion." [GOC:TermGenie]
+def: "OBSOLETE. Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to calcium ion." [GOC:TermGenie]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive regulation of calcium ion transport into cytosol involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie]
-is_a: GO:0010524 ! positive regulation of calcium ion transport into cytosol
-intersection_of: GO:0010524 ! positive regulation of calcium ion transport into cytosol
-intersection_of: part_of GO:0071277 ! cellular response to calcium ion
-relationship: part_of GO:0071277 ! cellular response to calcium ion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0010524
+consider: GO:0071277
created_by: al
creation_date: 2012-07-27T11:07:43Z
[Term]
id: GO:1901199
-name: positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress
+name: obsolete positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress
namespace: biological_process
-def: "Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress." [GOC:TermGenie]
+def: "OBSOLETE. Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress." [GOC:TermGenie]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive regulation of calcium ion transport into cytosol involved in cellular response to ionic osmotic stress" EXACT [GOC:TermGenie]
synonym: "positive regulation of calcium ion transport into cytosol involved in cellular salinity response" EXACT [GOC:TermGenie]
-is_a: GO:0010524 ! positive regulation of calcium ion transport into cytosol
-intersection_of: GO:0010524 ! positive regulation of calcium ion transport into cytosol
-intersection_of: part_of GO:0071472 ! cellular response to salt stress
-relationship: part_of GO:0071472 ! cellular response to salt stress
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0010524
+consider: GO:0071472
created_by: al
creation_date: 2012-07-27T11:09:37Z
[Term]
id: GO:1901200
-name: negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress
+name: obsolete negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress
namespace: biological_process
-def: "Any negative regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress." [GOC:TermGenie]
+def: "OBSOLETE. Any negative regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress." [GOC:TermGenie]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "negative regulation of calcium ion transport into cytosol involved in cellular response to ionic osmotic stress" EXACT [GOC:TermGenie]
synonym: "negative regulation of calcium ion transport into cytosol involved in cellular salinity response" EXACT [GOC:TermGenie]
-is_a: GO:0010523 ! negative regulation of calcium ion transport into cytosol
-intersection_of: GO:0010523 ! negative regulation of calcium ion transport into cytosol
-intersection_of: part_of GO:0071472 ! cellular response to salt stress
-relationship: part_of GO:0071472 ! cellular response to salt stress
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0010523
+consider: GO:0071472
created_by: al
creation_date: 2012-07-27T11:11:09Z
@@ -505508,7 +522948,10 @@
xref: MetaCyc:TRANS-RXN-242B
xref: RHEA:35027
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch EC:7.3.2.6
+property_value: skos:exactMatch RHEA:35027
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-08-07T14:47:36Z
@@ -508741,7 +526184,6 @@
synonym: "regulation of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie]
is_a: GO:0006521 ! regulation of amino acid metabolic process
is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0042762 ! regulation of sulfur metabolic process
is_a: GO:0051174 ! regulation of phosphorus metabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
@@ -508781,7 +526223,6 @@
synonym: "negative regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie]
synonym: "negative regulation of tetrapyrrole formation from glycine and succinyl-CoA" EXACT [GOC:TermGenie]
synonym: "negative regulation of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie]
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0045763 ! negative regulation of amino acid metabolic process
is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process
is_a: GO:0045936 ! negative regulation of phosphate metabolic process
@@ -508823,7 +526264,6 @@
synonym: "upregulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA" EXACT [GOC:TermGenie]
synonym: "upregulation of tetrapyrrole formation from glycine and succinyl-CoA" EXACT [GOC:TermGenie]
synonym: "upregulation of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie]
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0045764 ! positive regulation of amino acid metabolic process
is_a: GO:0045937 ! positive regulation of phosphate metabolic process
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
@@ -509979,24 +527419,26 @@
[Term]
id: GO:1901481
-name: L-glutamate import involved in cellular response to nitrogen starvation
+name: obsolete L-glutamate import involved in cellular response to nitrogen starvation
namespace: biological_process
-def: "Any L-glutamate import that is involved in cellular response to nitrogen starvation." [GOC:TermGenie]
+def: "OBSOLETE. Any L-glutamate import that is involved in cellular response to nitrogen starvation." [GOC:TermGenie]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "L-glutamate uptake involved in cellular response to nitrogen starvation" EXACT [GOC:TermGenie]
-is_a: GO:0051938 ! L-glutamate import
-intersection_of: GO:0051938 ! L-glutamate import
-intersection_of: part_of GO:0006995 ! cellular response to nitrogen starvation
-relationship: part_of GO:0006995 ! cellular response to nitrogen starvation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0006995
+consider: GO:0051938
created_by: al
creation_date: 2012-10-08T08:32:29Z
[Term]
id: GO:1901482
-name: L-lysine import into vacuole involved in cellular response to nitrogen starvation
+name: obsolete L-lysine import into vacuole involved in cellular response to nitrogen starvation
namespace: biological_process
-def: "A L-lysine import into the vacuole that is involved in cellular response to nitrogen starvation." [GOC:TermGenie]
-is_a: GO:0090517 ! L-lysine transmembrane import into vacuole
-relationship: part_of GO:0006995 ! cellular response to nitrogen starvation
+def: "OBSOLETE. A L-lysine import into the vacuole that is involved in cellular response to nitrogen starvation." [GOC:TermGenie]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: al
creation_date: 2012-10-08T08:34:03Z
@@ -511809,7 +529251,6 @@
name: dethiobiotin binding
namespace: molecular_function
def: "Binding to dethiobiotin." [GOC:TermGenie]
-is_a: GO:0033218 ! amide binding
is_a: GO:0033293 ! monocarboxylic acid binding
is_a: GO:1901363 ! heterocyclic compound binding
created_by: al
@@ -511821,7 +529262,6 @@
namespace: molecular_function
def: "Enables the transfer of dethiobiotin from one side of a membrane to the other." [GOC:TermGenie]
is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity
-is_a: GO:0042887 ! amide transmembrane transporter activity
created_by: al
creation_date: 2012-11-08T14:42:53Z
@@ -512135,9 +529575,10 @@
[Term]
id: GO:1901622
-name: positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
+name: obsolete positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning." [GOC:TermGenie]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning." [GOC:TermGenie]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning" NARROW [GOC:TermGenie]
synonym: "activation of hh signaling pathway involved in dorsal/ventral neural tube patterning" NARROW [GOC:TermGenie]
synonym: "activation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning" NARROW [GOC:TermGenie]
@@ -512157,11 +529598,10 @@
synonym: "upregulation of hh signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie]
synonym: "upregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie]
synonym: "upregulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie]
-is_a: GO:0045880 ! positive regulation of smoothened signaling pathway
-is_a: GO:1901620 ! regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0060831 ! smoothened signaling pathway involved in dorsal/ventral neural tube patterning
-relationship: positively_regulates GO:0060831 ! smoothened signaling pathway involved in dorsal/ventral neural tube patterning
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0009953
+consider: GO:0045880
created_by: krc
creation_date: 2012-11-13T20:12:06Z
@@ -512888,19 +530328,17 @@
[Term]
id: GO:1901667
-name: negative regulation of skeletal muscle satellite cell activation involved in skeletal muscle regeneration
+name: obsolete negative regulation of skeletal muscle satellite cell activation involved in skeletal muscle regeneration
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell activation involved in skeletal muscle regeneration." [GOC:dph, GOC:TermGenie, PMID:21272575]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell activation involved in skeletal muscle regeneration." [GOC:dph, GOC:TermGenie, PMID:21272575]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of satellite cell activation involved in skeletal muscle regeneration" EXACT [GOC:TermGenie]
synonym: "down-regulation of satellite cell activation involved in skeletal muscle regeneration" EXACT [GOC:TermGenie]
synonym: "downregulation of satellite cell activation involved in skeletal muscle regeneration" EXACT [GOC:TermGenie]
synonym: "inhibition of satellite cell activation involved in skeletal muscle regeneration" NARROW [GOC:TermGenie]
-is_a: GO:0014717 ! regulation of satellite cell activation involved in skeletal muscle regeneration
-is_a: GO:0043417 ! negative regulation of skeletal muscle tissue regeneration
-is_a: GO:0050866 ! negative regulation of cell activation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0014901 ! satellite cell activation involved in skeletal muscle regeneration
-relationship: negatively_regulates GO:0014901 ! satellite cell activation involved in skeletal muscle regeneration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0014901
created_by: dph
creation_date: 2012-11-21T16:21:11Z
@@ -513746,8 +531184,8 @@
is_a: GO:0062012 ! regulation of small molecule metabolic process
is_a: GO:2000282 ! regulation of amino acid biosynthetic process
intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0009090 ! homoserine biosynthetic process
-relationship: regulates GO:0009090 ! homoserine biosynthetic process
+intersection_of: regulates GO:0009090 ! L-homoserine biosynthetic process
+relationship: regulates GO:0009090 ! L-homoserine biosynthetic process
created_by: mcc
creation_date: 2012-12-19T16:01:56Z
@@ -513784,8 +531222,8 @@
is_a: GO:1901710 ! regulation of homoserine biosynthetic process
is_a: GO:2000283 ! negative regulation of amino acid biosynthetic process
intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0009090 ! homoserine biosynthetic process
-relationship: negatively_regulates GO:0009090 ! homoserine biosynthetic process
+intersection_of: negatively_regulates GO:0009090 ! L-homoserine biosynthetic process
+relationship: negatively_regulates GO:0009090 ! L-homoserine biosynthetic process
created_by: mcc
creation_date: 2012-12-19T16:02:00Z
@@ -513822,8 +531260,8 @@
is_a: GO:1901710 ! regulation of homoserine biosynthetic process
is_a: GO:2000284 ! positive regulation of amino acid biosynthetic process
intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0009090 ! homoserine biosynthetic process
-relationship: positively_regulates GO:0009090 ! homoserine biosynthetic process
+intersection_of: positively_regulates GO:0009090 ! L-homoserine biosynthetic process
+relationship: positively_regulates GO:0009090 ! L-homoserine biosynthetic process
created_by: mcc
creation_date: 2012-12-19T16:02:05Z
@@ -513856,7 +531294,7 @@
synonym: "negative regulation of urea catabolism" EXACT [GOC:TermGenie]
synonym: "negative regulation of urea decomposition" EXACT [GOC:TermGenie]
synonym: "negative regulation of urea degradation" EXACT [GOC:TermGenie]
-is_a: GO:0034252 ! negative regulation of amide catabolic process
+is_a: GO:0009895 ! negative regulation of catabolic process
is_a: GO:0034254 ! regulation of urea catabolic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
is_a: GO:1903315 ! negative regulation of nitrogen cycle metabolic process
@@ -513895,7 +531333,7 @@
synonym: "upregulation of urea catabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of urea decomposition" EXACT [GOC:TermGenie]
synonym: "upregulation of urea degradation" EXACT [GOC:TermGenie]
-is_a: GO:0034253 ! positive regulation of amide catabolic process
+is_a: GO:0009896 ! positive regulation of catabolic process
is_a: GO:0034254 ! regulation of urea catabolic process
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
is_a: GO:1903316 ! positive regulation of nitrogen cycle metabolic process
@@ -514471,7 +531909,6 @@
synonym: "leukotriene D4 catabolism" EXACT [GOC:TermGenie]
synonym: "leukotriene D4 degradation" EXACT [GOC:TermGenie]
is_a: GO:0036100 ! leukotriene catabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0044273 ! sulfur compound catabolic process
is_a: GO:1901523 ! icosanoid catabolic process
created_by: yaf
@@ -514487,7 +531924,6 @@
synonym: "leukotriene D4 formation" EXACT [GOC:TermGenie]
synonym: "leukotriene D4 synthesis" EXACT [GOC:TermGenie]
is_a: GO:0019370 ! leukotriene biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0044272 ! sulfur compound biosynthetic process
is_a: GO:1901570 ! fatty acid derivative biosynthetic process
created_by: yaf
@@ -514819,7 +532255,6 @@
synonym: "lincomycin degradation" EXACT [GOC:TermGenie]
is_a: GO:0016145 ! S-glycoside catabolic process
is_a: GO:0042219 ! modified amino acid catabolic process
-is_a: GO:0043603 ! amide metabolic process
created_by: yaf
creation_date: 2013-01-15T11:53:57Z
@@ -514835,7 +532270,6 @@
xref: MetaCyc:PWY-6955
is_a: GO:0016144 ! S-glycoside biosynthetic process
is_a: GO:0042398 ! modified amino acid biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
created_by: yaf
creation_date: 2013-01-15T11:54:01Z
@@ -515021,10 +532455,16 @@
synonym: "benzoyl-CoA breakdown" EXACT [GOC:TermGenie]
synonym: "benzoyl-CoA catabolism" EXACT [GOC:TermGenie]
synonym: "benzoyl-CoA degradation" EXACT [GOC:TermGenie]
+xref: MetaCyc:CENTBENZCOA-PWY
+xref: MetaCyc:P321-PWY
+xref: MetaCyc:PWY-1361
is_a: GO:0044273 ! sulfur compound catabolic process
is_a: GO:0072523 ! purine-containing compound catabolic process
is_a: GO:1901292 ! nucleoside phosphate catabolic process
is_a: GO:1901787 ! benzoyl-CoA metabolic process
+property_value: skos:narrowMatch MetaCyc:CENTBENZCOA-PWY
+property_value: skos:narrowMatch MetaCyc:P321-PWY
+property_value: skos:narrowMatch MetaCyc:PWY-1361
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
created_by: yaf
creation_date: 2013-01-16T11:13:59Z
@@ -515066,6 +532506,7 @@
synonym: "3-(2,3-dihydroxyphenyl)propanoate degradation" EXACT [GOC:TermGenie]
is_a: GO:0019614 ! catechol-containing compound catabolic process
is_a: GO:0072329 ! monocarboxylic acid catabolic process
+property_value: skos:broadMatch MetaCyc:HCAMHPDEG-PWY
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI
@@ -515109,6 +532550,7 @@
synonym: "3-(3-hydroxyphenyl)propanoate catabolism" EXACT [GOC:TermGenie]
synonym: "3-(3-hydroxyphenyl)propanoate degradation" EXACT [GOC:TermGenie]
is_a: GO:0072329 ! monocarboxylic acid catabolic process
+property_value: skos:broadMatch MetaCyc:PWY0-1277
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
created_by: yaf
creation_date: 2013-01-16T11:47:17Z
@@ -515194,7 +532636,6 @@
synonym: "negative regulation of proteasome-mediated protein catabolism" EXACT [GOC:TermGenie]
is_a: GO:0042177 ! negative regulation of protein catabolic process
is_a: GO:0061136 ! regulation of proteasomal protein catabolic process
-is_a: GO:1903051 ! negative regulation of proteolysis involved in protein catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0010498 ! proteasomal protein catabolic process
relationship: negatively_regulates GO:0010498 ! proteasomal protein catabolic process
@@ -515222,7 +532663,6 @@
synonym: "upregulation of proteasome-mediated protein catabolism" EXACT [GOC:TermGenie]
is_a: GO:0045732 ! positive regulation of protein catabolic process
is_a: GO:0061136 ! regulation of proteasomal protein catabolic process
-is_a: GO:1903052 ! positive regulation of proteolysis involved in protein catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0010498 ! proteasomal protein catabolic process
relationship: positively_regulates GO:0010498 ! proteasomal protein catabolic process
@@ -515352,6 +532792,7 @@
synonym: "capsanthin formation" EXACT [GOC:TermGenie]
synonym: "capsanthin synthesis" EXACT [GOC:TermGenie]
is_a: GO:0016123 ! xanthophyll biosynthetic process
+property_value: skos:broadMatch MetaCyc:PWY-5174
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
created_by: yaf
creation_date: 2013-01-22T10:21:50Z
@@ -516300,6 +533741,7 @@
synonym: "capsorubin formation" EXACT [GOC:TermGenie]
synonym: "capsorubin synthesis" EXACT [GOC:TermGenie]
is_a: GO:0016123 ! xanthophyll biosynthetic process
+property_value: skos:broadMatch MetaCyc:PWY-5174
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
created_by: yaf
creation_date: 2013-02-04T10:50:26Z
@@ -517951,30 +535393,31 @@
[Term]
id: GO:1901963
-name: regulation of cell proliferation involved in outflow tract morphogenesis
+name: obsolete regulation of cell proliferation involved in outflow tract morphogenesis
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760]
-is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis
-relationship: regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003151
+consider: GO:0042127
created_by: dph
creation_date: 2013-02-20T20:30:26Z
[Term]
id: GO:1901964
-name: positive regulation of cell proliferation involved in outflow tract morphogenesis
+name: obsolete positive regulation of cell proliferation involved in outflow tract morphogenesis
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of cell proliferation involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "up regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
-is_a: GO:1901963 ! regulation of cell proliferation involved in outflow tract morphogenesis
-is_a: GO:2000138 ! positive regulation of cell proliferation involved in heart morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis
-relationship: positively_regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003151
+consider: GO:0008284
created_by: dph
creation_date: 2013-02-20T20:30:31Z
@@ -518652,7 +536095,6 @@
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of amyloid-beta formation." [GOC:dph, GOC:TermGenie, PMID:17098871]
synonym: "regulation of beta-amyloid formation" EXACT []
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:1902991 ! regulation of amyloid precursor protein catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0034205 ! amyloid-beta formation
@@ -518670,7 +536112,6 @@
synonym: "up regulation of beta-amyloid formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of beta-amyloid formation" EXACT [GOC:TermGenie]
synonym: "upregulation of beta-amyloid formation" EXACT [GOC:TermGenie]
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:1902003 ! regulation of amyloid-beta formation
is_a: GO:1902993 ! positive regulation of amyloid precursor protein catabolic process
intersection_of: GO:0065007 ! biological regulation
@@ -520275,14 +537716,15 @@
[Term]
id: GO:1902089
-name: cell wall polysaccharide catabolic process involved in lateral root development
+name: obsolete cell wall polysaccharide catabolic process involved in lateral root development
namespace: biological_process
-def: "Any cell wall polysaccharide catabolic process that is involved in lateral root development." [GOC:TermGenie, PMID:23479623]
+def: "OBSOLETE. Any cell wall polysaccharide catabolic process that is involved in lateral root development." [GOC:TermGenie, PMID:23479623]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "cell wall polysaccharide breakdown involved in lateral root development" EXACT [GOC:TermGenie]
-is_a: GO:0044347 ! cell wall polysaccharide catabolic process
-intersection_of: GO:0044347 ! cell wall polysaccharide catabolic process
-intersection_of: part_of GO:0048527 ! lateral root development
-relationship: part_of GO:0048527 ! lateral root development
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0044347
+consider: GO:0048527
created_by: tb
creation_date: 2013-04-26T18:34:53Z
@@ -523392,9 +540834,10 @@
[Term]
id: GO:1902258
-name: positive regulation of apoptotic process involved in outflow tract morphogenesis
+name: obsolete positive regulation of apoptotic process involved in outflow tract morphogenesis
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic process involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
@@ -523404,11 +540847,10 @@
synonym: "up-regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
-is_a: GO:1902256 ! regulation of apoptotic process involved in outflow tract morphogenesis
-is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis
-relationship: positively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003151
+consider: GO:1904747
created_by: dph
creation_date: 2013-06-24T19:12:42Z
@@ -523844,16 +541286,17 @@
[Term]
id: GO:1902286
-name: semaphorin-plexin signaling pathway involved in dendrite guidance
+name: obsolete semaphorin-plexin signaling pathway involved in dendrite guidance
namespace: biological_process
-def: "Any semaphorin-plexin signaling pathway that is involved in dendrite guidance." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22790009]
+def: "OBSOLETE. Any semaphorin-plexin signaling pathway that is involved in dendrite guidance." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22790009]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "semaphorin-plexin signaling pathway involved in dendritic guidance" EXACT [GOC:TermGenie]
synonym: "semaphorin-plexin signalling pathway involved in dendrite guidance" EXACT [GOC:TermGenie]
synonym: "semaphorin-plexin signalling pathway involved in dendritic guidance" EXACT [GOC:TermGenie]
-is_a: GO:1902285 ! semaphorin-plexin signaling pathway involved in neuron projection guidance
-intersection_of: GO:0071526 ! semaphorin-plexin signaling pathway
-intersection_of: part_of GO:0070983 ! dendrite guidance
-relationship: part_of GO:0070983 ! dendrite guidance
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0070983
+consider: GO:0071526
created_by: pr
creation_date: 2013-07-08T16:06:55Z
@@ -525437,9 +542880,10 @@
[Term]
id: GO:1902378
-name: VEGF-activated neuropilin signaling pathway involved in axon guidance
+name: obsolete VEGF-activated neuropilin signaling pathway involved in axon guidance
namespace: biological_process
-def: "Any VEGF-activated neuropilin signaling pathway that is involved in axon guidance." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21658587]
+def: "OBSOLETE. Any VEGF-activated neuropilin signaling pathway that is involved in axon guidance." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21658587]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon chemotaxis" RELATED [GOC:TermGenie]
synonym: "vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon growth cone guidance" RELATED [GOC:TermGenie]
synonym: "vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon guidance" RELATED [GOC:TermGenie]
@@ -525451,10 +542895,10 @@
synonym: "VEGF-Npn-1 signaling involved in axon growth cone guidance" NARROW [GOC:TermGenie]
synonym: "VEGF-Npn-1 signaling involved in axon guidance" NARROW [GOC:TermGenie]
synonym: "VEGF-Npn-1 signaling involved in axon pathfinding" NARROW [GOC:TermGenie]
-is_a: GO:0038190 ! VEGF-activated neuropilin signaling pathway
-intersection_of: GO:0038190 ! VEGF-activated neuropilin signaling pathway
-intersection_of: part_of GO:0007411 ! axon guidance
-relationship: part_of GO:0007411 ! axon guidance
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007411
+consider: GO:0038190
created_by: bf
creation_date: 2013-09-02T13:44:13Z
@@ -526158,7 +543602,6 @@
synonym: "downregulation of beta-amyloid formation" EXACT [GOC:TermGenie]
synonym: "inhibition of beta-amyloid formation" NARROW [GOC:TermGenie]
synonym: "negative regulation of beta-amyloid formation" EXACT []
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:1902003 ! regulation of amyloid-beta formation
is_a: GO:1902992 ! negative regulation of amyloid precursor protein catabolic process
intersection_of: GO:0065007 ! biological regulation
@@ -527814,16 +545257,17 @@
[Term]
id: GO:1902550
-name: lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis
+name: obsolete lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis
namespace: biological_process
-def: "Any lymphoid lineage cell migration into thymus that is involved in thymus epithelium morphogenesis." [GOC:cvs, GOC:TermGenie, PMID:22342843]
+def: "OBSOLETE. Any lymphoid lineage cell migration into thymus that is involved in thymus epithelium morphogenesis." [GOC:cvs, GOC:TermGenie, PMID:22342843]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "lymphoid lineage cell migration into thymus involved in thymic epithelium morphogenesis" EXACT [GOC:TermGenie]
synonym: "lymphoid lineage restricted progenitor cell migration into thymus involved in thymic epithelium morphogenesis" EXACT [GOC:TermGenie]
synonym: "lymphoid lineage restricted progenitor cell migration into thymus involved in thymus epithelium morphogenesis" EXACT [GOC:TermGenie]
-is_a: GO:0097535 ! lymphoid lineage cell migration into thymus
-intersection_of: GO:0097535 ! lymphoid lineage cell migration into thymus
-intersection_of: part_of GO:0097536 ! thymus epithelium morphogenesis
-relationship: part_of GO:0097536 ! thymus epithelium morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0097535
+consider: GO:0097536
created_by: pr
creation_date: 2013-12-04T21:13:33Z
@@ -528572,7 +546016,6 @@
def: "The directed movement of sulfathiazole across a membrane." [GO_REF:0000069, GOC:pr, GOC:TermGenie]
synonym: "sulfathiazole transport" BROAD []
synonym: "sulphathiazole transport" BROAD []
-is_a: GO:0042886 ! amide transport
is_a: GO:0045117 ! azole transmembrane transport
is_a: GO:0072348 ! sulfur compound transport
created_by: pr
@@ -529154,25 +546597,27 @@
[Term]
id: GO:1902637
-name: neural crest cell differentiation involved in thymus development
+name: obsolete neural crest cell differentiation involved in thymus development
namespace: biological_process
-def: "Any neural crest cell differentiation that is involved in thymus development." [GO_REF:0000060, GOC:nhn, GOC:TermGenie, PMID:15741317, PMID:18292542]
-is_a: GO:0014033 ! neural crest cell differentiation
-intersection_of: GO:0014033 ! neural crest cell differentiation
-intersection_of: part_of GO:0048538 ! thymus development
-relationship: part_of GO:0048538 ! thymus development
+def: "OBSOLETE. Any neural crest cell differentiation that is involved in thymus development." [GO_REF:0000060, GOC:nhn, GOC:TermGenie, PMID:15741317, PMID:18292542]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0014033
+consider: GO:0048538
created_by: pr
creation_date: 2014-01-21T10:03:20Z
[Term]
id: GO:1902638
-name: neural crest cell differentiation involved in parathyroid gland development
+name: obsolete neural crest cell differentiation involved in parathyroid gland development
namespace: biological_process
-def: "Any neural crest cell differentiation that is involved in parathyroid gland development." [GO_REF:0000060, GOC:nhn, GOC:TermGenie, PMID:15741317]
-is_a: GO:0014033 ! neural crest cell differentiation
-intersection_of: GO:0014033 ! neural crest cell differentiation
-intersection_of: part_of GO:0060017 ! parathyroid gland development
-relationship: part_of GO:0060017 ! parathyroid gland development
+def: "OBSOLETE. Any neural crest cell differentiation that is involved in parathyroid gland development." [GO_REF:0000060, GOC:nhn, GOC:TermGenie, PMID:15741317]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0014033
+consider: GO:0060017
created_by: pr
creation_date: 2014-01-21T10:03:29Z
@@ -530429,31 +547874,33 @@
[Term]
id: GO:1902696
-name: glycine catabolic process to isobutanol
+name: obsolete glycine catabolic process to isobutanol
namespace: biological_process
alt_id: GO:1990293
-def: "The chemical reactions and pathways resulting in the breakdown of glycine to isobutanol." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:23642236]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glycine to isobutanol." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:23642236]
+comment: This term was obsoleted because it is beyond the specificity reppresented in GO.
synonym: "glycine breakdown to isobutanol" EXACT [GOC:TermGenie]
synonym: "glycine catabolism to isobutanol" EXACT [GOC:TermGenie]
synonym: "glycine degradation to isobutanol" EXACT [GOC:TermGenie]
-is_a: GO:0006546 ! glycine catabolic process
-is_a: GO:0034308 ! primary alcohol metabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31221" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0006546
created_by: tb
creation_date: 2014-02-19T18:00:12Z
[Term]
id: GO:1902697
-name: L-valine catabolic process to isobutanol
+name: obsolete L-valine catabolic process to isobutanol
namespace: biological_process
-alt_id: GO:1990292
-def: "The chemical reactions and pathways resulting in the breakdown of L-valine to isobutanol." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:9748245]
+def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of L-valine to isobutanol." [GOC:mengo_curators, GOC:TermGenie, PMID:9748245]
+comment: This term was obsoleted because it is beyond the specificity reppresented in GO.
synonym: "valine breakdown to isobutanol" EXACT [GOC:TermGenie]
synonym: "valine catabolism to isobutanol" EXACT [GOC:TermGenie]
synonym: "valine degradation to isobutanol" EXACT [GOC:TermGenie]
-xref: MetaCyc:PWY-5057
-is_a: GO:0006574 ! L-valine catabolic process
-is_a: GO:0034308 ! primary alcohol metabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30202" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31221" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0006574
created_by: tb
creation_date: 2014-02-19T18:28:19Z
@@ -534552,7 +551999,6 @@
namespace: molecular_function
def: "Binding to phosphatidylinositol bisphosphate." [GO_REF:0000067, GOC:bhm, GOC:TermGenie, PMID:18690034]
comment: An example of this is KCNJ2 in human (P63252) in PMID:18690034 (inferred from direct assay)
-xref: Reactome:R-HSA-8870332 "PTPN13:PLEKHA1,2 bind PI(3,4)P2"
is_a: GO:1901981 ! phosphatidylinositol phosphate binding
created_by: bhm
creation_date: 2014-04-25T15:14:12Z
@@ -536166,8 +553612,8 @@
is_a: GO:0062012 ! regulation of small molecule metabolic process
is_a: GO:2000282 ! regulation of amino acid biosynthetic process
intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0019878 ! lysine biosynthetic process via aminoadipic acid
-relationship: regulates GO:0019878 ! lysine biosynthetic process via aminoadipic acid
+intersection_of: regulates GO:0019878 ! L-lysine biosynthetic process via aminoadipic acid
+relationship: regulates GO:0019878 ! L-lysine biosynthetic process via aminoadipic acid
created_by: al
creation_date: 2014-05-07T08:07:08Z
@@ -536219,8 +553665,8 @@
is_a: GO:1902986 ! regulation of lysine biosynthetic process via aminoadipic acid
is_a: GO:2000283 ! negative regulation of amino acid biosynthetic process
intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0019878 ! lysine biosynthetic process via aminoadipic acid
-relationship: negatively_regulates GO:0019878 ! lysine biosynthetic process via aminoadipic acid
+intersection_of: negatively_regulates GO:0019878 ! L-lysine biosynthetic process via aminoadipic acid
+relationship: negatively_regulates GO:0019878 ! L-lysine biosynthetic process via aminoadipic acid
created_by: al
creation_date: 2014-05-07T08:07:15Z
@@ -537414,10 +554860,10 @@
[Term]
id: GO:1903050
-name: regulation of proteolysis involved in protein catabolic process
+name: obsolete regulation of proteolysis involved in protein catabolic process
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of proteolysis involved in cellular catabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18307834]
-comment: overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP)
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of proteolysis involved in cellular catabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18307834]
+comment: overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP). The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
synonym: "regulation of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie]
synonym: "regulation of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie]
synonym: "regulation of peptidolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie]
@@ -537425,20 +554871,19 @@
synonym: "regulation of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie]
synonym: "regulation of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie]
synonym: "regulation of proteolysis involved in cellular protein catabolic process" EXACT []
-is_a: GO:0030162 ! regulation of proteolysis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0051603 ! proteolysis involved in protein catabolic process
-relationship: regulates GO:0051603 ! proteolysis involved in protein catabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31208" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0042176
created_by: rl
creation_date: 2014-05-22T18:00:45Z
[Term]
id: GO:1903051
-name: negative regulation of proteolysis involved in protein catabolic process
+name: obsolete negative regulation of proteolysis involved in protein catabolic process
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in protein catabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18307834]
-comment: Overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP).
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in protein catabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18307834]
+comment: Overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP). The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
synonym: "down regulation of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie]
synonym: "down regulation of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie]
synonym: "down regulation of peptidolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie]
@@ -537474,21 +554919,19 @@
synonym: "negative regulation of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie]
synonym: "negative regulation of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie]
synonym: "negative regulation of proteolysis involved in cellular protein catabolic process" EXACT []
-is_a: GO:0045861 ! negative regulation of proteolysis
-is_a: GO:1903050 ! regulation of proteolysis involved in protein catabolic process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0051603 ! proteolysis involved in protein catabolic process
-relationship: negatively_regulates GO:0051603 ! proteolysis involved in protein catabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31208" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0042177
created_by: rl
creation_date: 2014-05-22T18:00:51Z
[Term]
id: GO:1903052
-name: positive regulation of proteolysis involved in protein catabolic process
+name: obsolete positive regulation of proteolysis involved in protein catabolic process
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of proteolysis involved in protein catabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18307834]
-comment: overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP)
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of proteolysis involved in protein catabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18307834]
+comment: overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP). The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
synonym: "activation of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie]
synonym: "activation of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie]
synonym: "activation of peptidolysis involved in cellular protein catabolic process" NARROW [GOC:TermGenie]
@@ -537524,12 +554967,10 @@
synonym: "upregulation of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie]
synonym: "upregulation of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie]
synonym: "upregulation of proteolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie]
-is_a: GO:0045862 ! positive regulation of proteolysis
-is_a: GO:1903050 ! regulation of proteolysis involved in protein catabolic process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0051603 ! proteolysis involved in protein catabolic process
-relationship: positively_regulates GO:0051603 ! proteolysis involved in protein catabolic process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31208" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0045732
created_by: rl
creation_date: 2014-05-22T18:00:57Z
@@ -538296,7 +555737,6 @@
name: 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport
namespace: biological_process
def: "The process in which 5-amino-1-ribofuranosylimidazole-4-carboxamide is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:24778186]
-is_a: GO:0042886 ! amide transport
is_a: GO:0045117 ! azole transmembrane transport
is_a: GO:1901264 ! carbohydrate derivative transport
created_by: mcc
@@ -538308,7 +555748,6 @@
namespace: molecular_function
def: "Enables the transfer of 5-amino-1-ribofuranosylimidazole-4-carboxamide from one side of a membrane to the other." [GO_REF:0000066, GOC:TermGenie, PMID:24778186]
synonym: "acadesine transporter activity" EXACT []
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:1901474 ! azole transmembrane transporter activity
is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity
relationship: part_of GO:1903088 ! 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport
@@ -540446,27 +557885,27 @@
[Term]
id: GO:1903214
-name: regulation of protein targeting to mitochondrion
+name: obsolete regulation of protein targeting to mitochondrion
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie]
+comment: The reason for obsoletion is that this term was added in error.
synonym: "regulation of mitochondrial protein import" RELATED [GOC:TermGenie]
synonym: "regulation of mitochondrial translocation" RELATED [GOC:TermGenie]
synonym: "regulation of protein import into mitochondrion" EXACT [GOC:TermGenie]
synonym: "regulation of protein targeting to mitochondria" EXACT [GOC:TermGenie]
synonym: "regulation of protein-mitochondrial targeting" EXACT [GOC:TermGenie]
-is_a: GO:1903533 ! regulation of protein targeting
-is_a: GO:1903747 ! regulation of establishment of protein localization to mitochondrion
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0006626 ! protein targeting to mitochondrion
-relationship: regulates GO:0006626 ! protein targeting to mitochondrion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30349" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:1903747
created_by: bf
creation_date: 2014-07-24T10:17:13Z
[Term]
id: GO:1903215
-name: negative regulation of protein targeting to mitochondrion
+name: obsolete negative regulation of protein targeting to mitochondrion
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to mitochondrion." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21370995]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to mitochondrion." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21370995]
+comment: The reason for obsoletion is that this term was added in error.
synonym: "down regulation of mitochondrial protein import" RELATED [GOC:TermGenie]
synonym: "down regulation of mitochondrial translocation" RELATED [GOC:TermGenie]
synonym: "down regulation of protein import into mitochondrion" EXACT [GOC:TermGenie]
@@ -540496,33 +557935,32 @@
synonym: "negative regulation of protein import into mitochondrion" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein targeting to mitochondria" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein-mitochondrial targeting" EXACT [GOC:TermGenie]
-is_a: GO:1903214 ! regulation of protein targeting to mitochondrion
-is_a: GO:1903748 ! negative regulation of establishment of protein localization to mitochondrion
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0006626 ! protein targeting to mitochondrion
-relationship: negatively_regulates GO:0006626 ! protein targeting to mitochondrion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30349" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:1903748
created_by: bf
creation_date: 2014-07-24T10:17:19Z
[Term]
id: GO:1903216
-name: regulation of protein processing involved in protein targeting to mitochondrion
+name: obsolete regulation of protein processing involved in protein targeting to mitochondrion
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21370995]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21370995]
+comment: The reason for obsoletion is that this term was added in error.
synonym: "regulation of mitochondrial processing" BROAD [GOC:TermGenie]
synonym: "regulation of mitochondrial protein processing during import" RELATED [GOC:TermGenie]
-is_a: GO:0070613 ! regulation of protein processing
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0006627 ! protein processing involved in protein targeting to mitochondrion
-relationship: regulates GO:0006627 ! protein processing involved in protein targeting to mitochondrion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30349" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:1903747
created_by: bf
creation_date: 2014-07-24T10:20:54Z
[Term]
id: GO:1903217
-name: negative regulation of protein processing involved in protein targeting to mitochondrion
+name: obsolete negative regulation of protein processing involved in protein targeting to mitochondrion
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21370995]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21370995]
+comment: The reason for obsoletion is that this term was added in error.
synonym: "down regulation of mitochondrial protein processing during import" RELATED [GOC:TermGenie]
synonym: "down regulation of protein processing involved in protein targeting to mitochondrion" EXACT [GOC:TermGenie]
synonym: "down-regulation of mitochondrial protein processing during import" RELATED [GOC:TermGenie]
@@ -540532,11 +557970,9 @@
synonym: "inhibition of mitochondrial protein processing during import" RELATED [GOC:TermGenie]
synonym: "inhibition of protein processing involved in protein targeting to mitochondrion" NARROW [GOC:TermGenie]
synonym: "negative regulation of mitochondrial protein processing during import" RELATED [GOC:TermGenie]
-is_a: GO:0010955 ! negative regulation of protein processing
-is_a: GO:1903216 ! regulation of protein processing involved in protein targeting to mitochondrion
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0006627 ! protein processing involved in protein targeting to mitochondrion
-relationship: negatively_regulates GO:0006627 ! protein processing involved in protein targeting to mitochondrion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30349" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:1903748
created_by: bf
creation_date: 2014-07-24T10:21:00Z
@@ -547043,9 +564479,10 @@
[Term]
id: GO:1903554
-name: G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium
+name: obsolete G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium
namespace: biological_process
-def: "A G protein-coupled receptor signaling pathway that is involved in the defense response to Gram-negative bacterium." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, PMID:25303524]
+def: "OBSOLETE. A G protein-coupled receptor signaling pathway that is involved in the defense response to Gram-negative bacterium." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, PMID:25303524]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "G protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie]
synonym: "G protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie]
synonym: "G protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie]
@@ -547094,10 +564531,10 @@
synonym: "GPCR signalling pathway involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie]
synonym: "GPCR signalling pathway involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie]
synonym: "GPCR signalling pathway involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie]
-is_a: GO:0007186 ! G protein-coupled receptor signaling pathway
-intersection_of: GO:0007186 ! G protein-coupled receptor signaling pathway
-intersection_of: part_of GO:0050829 ! defense response to Gram-negative bacterium
-relationship: part_of GO:0050829 ! defense response to Gram-negative bacterium
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007186
+consider: GO:0050829
created_by: kmv
creation_date: 2014-10-20T17:51:13Z
@@ -547245,19 +564682,19 @@
[Term]
id: GO:1903563
-name: microtubule bundle formation involved in horsetail-astral microtubule organization
+name: obsolete microtubule bundle formation involved in horsetail-astral microtubule organization
namespace: biological_process
-def: "Any microtubule bundle formation that is involved in horsetail-astral microtubule organization." [GO_REF:0000060, GOC:TermGenie, PMID:15647375]
+def: "OBSOLETE. Any microtubule bundle formation that is involved in horsetail-astral microtubule organization." [GO_REF:0000060, GOC:TermGenie, PMID:15647375]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "microtubule bundle formation involved in horsetail-astral microtubule array organization" EXACT [GOC:TermGenie]
synonym: "microtubule bundle formation involved in horsetail-astral microtubule organisation" EXACT [GOC:TermGenie]
synonym: "microtubule bundling involved in horsetail-astral microtubule array organization" EXACT [GOC:TermGenie]
synonym: "microtubule bundling involved in horsetail-astral microtubule organisation" EXACT [GOC:TermGenie]
synonym: "microtubule bundling involved in horsetail-astral microtubule organization" EXACT [GOC:TermGenie]
-is_a: GO:0001578 ! microtubule bundle formation
-is_a: GO:1903046 ! meiotic cell cycle process
-intersection_of: GO:0001578 ! microtubule bundle formation
-intersection_of: part_of GO:0032118 ! horsetail-astral microtubule organization
-relationship: part_of GO:0032118 ! horsetail-astral microtubule organization
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001578
+consider: GO:0032118
created_by: vw
creation_date: 2014-10-23T11:06:35Z
@@ -548967,7 +566404,7 @@
synonym: "regulation of protein transport into mitochondrial outer membrane" EXACT [GOC:TermGenie]
is_a: GO:0010821 ! regulation of mitochondrion organization
is_a: GO:0060341 ! regulation of cellular localization
-is_a: GO:1903214 ! regulation of protein targeting to mitochondrion
+is_a: GO:0070201 ! regulation of establishment of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0045040 ! protein insertion into mitochondrial outer membrane
relationship: regulates GO:0045040 ! protein insertion into mitochondrial outer membrane
@@ -548999,8 +566436,8 @@
synonym: "negative regulation of protein import into mitochondrial outer membrane" EXACT []
synonym: "negative regulation of protein transport into mitochondrial outer membrane" EXACT [GOC:TermGenie]
is_a: GO:0010639 ! negative regulation of organelle organization
-is_a: GO:1903215 ! negative regulation of protein targeting to mitochondrion
is_a: GO:1903636 ! regulation of protein insertion into mitochondrial outer membrane
+is_a: GO:1904950 ! negative regulation of establishment of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0045040 ! protein insertion into mitochondrial outer membrane
relationship: negatively_regulates GO:0045040 ! protein insertion into mitochondrial outer membrane
@@ -549033,7 +566470,7 @@
synonym: "upregulation of protein transport into mitochondrial outer membrane" EXACT [GOC:TermGenie]
is_a: GO:0010638 ! positive regulation of organelle organization
is_a: GO:1903636 ! regulation of protein insertion into mitochondrial outer membrane
-is_a: GO:1903955 ! positive regulation of protein targeting to mitochondrion
+is_a: GO:1904951 ! positive regulation of establishment of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0045040 ! protein insertion into mitochondrial outer membrane
relationship: positively_regulates GO:0045040 ! protein insertion into mitochondrial outer membrane
@@ -549840,19 +567277,18 @@
[Term]
id: GO:1903682
-name: negative regulation of epithelial cell-cell adhesion involved in epithelium migration
+name: obsolete negative regulation of epithelial cell-cell adhesion involved in epithelium migration
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18394891]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18394891]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of epithelial cell-cell adhesion involved in epithelium migration" EXACT [GOC:TermGenie]
synonym: "down-regulation of epithelial cell-cell adhesion involved in epithelium migration" EXACT [GOC:TermGenie]
synonym: "downregulation of epithelial cell-cell adhesion involved in epithelium migration" EXACT [GOC:TermGenie]
synonym: "inhibition of epithelial cell-cell adhesion involved in epithelium migration" NARROW [GOC:TermGenie]
-is_a: GO:0022408 ! negative regulation of cell-cell adhesion
-is_a: GO:0051241 ! negative regulation of multicellular organismal process
-is_a: GO:1903681 ! regulation of epithelial cell-cell adhesion involved in epithelium migration
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0090137 ! epithelial cell-cell adhesion involved in epithelium migration
-relationship: negatively_regulates GO:0090137 ! epithelial cell-cell adhesion involved in epithelium migration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0022408
+consider: GO:0090132
created_by: als
creation_date: 2014-12-01T13:25:14Z
@@ -550389,7 +567825,7 @@
namespace: biological_process
def: "The directed movement of asparagine across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:18503766]
is_a: GO:0003333 ! amino acid transmembrane transport
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
is_a: GO:1905039 ! carboxylic acid transmembrane transport
created_by: vw
creation_date: 2014-12-06T08:17:55Z
@@ -550843,71 +568279,44 @@
[Term]
id: GO:1903747
-name: regulation of establishment of protein localization to mitochondrion
+name: regulation of protein localization to mitochondrion
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion." [GO_REF:0000058, GOC:TermGenie, PMID:16857185]
-synonym: "regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie]
-is_a: GO:0070201 ! regulation of establishment of protein localization
+def: "Any process that modulates the frequency, rate or extent of protein localization to mitochondrion." [GO_REF:0000058, GOC:TermGenie, PMID:16857185]
+is_a: GO:0032880 ! regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0072655 ! establishment of protein localization to mitochondrion
-relationship: regulates GO:0072655 ! establishment of protein localization to mitochondrion
+intersection_of: regulates GO:0070585 ! protein localization to mitochondrion
+relationship: regulates GO:0070585 ! protein localization to mitochondrion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30349" xsd:anyURI
created_by: krc
creation_date: 2014-12-12T22:18:09Z
[Term]
id: GO:1903748
-name: negative regulation of establishment of protein localization to mitochondrion
+name: negative regulation of protein localization to mitochondrion
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion." [GO_REF:0000058, GOC:TermGenie, PMID:16857185]
-synonym: "down regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "down regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie]
-synonym: "down regulation of establishment of protein localization to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "down-regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "down-regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie]
-synonym: "down-regulation of establishment of protein localization to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "downregulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "downregulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie]
-synonym: "downregulation of establishment of protein localization to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "inhibition of establishment of protein localisation to mitochondrion" NARROW [GOC:TermGenie]
-synonym: "inhibition of establishment of protein localization in mitochondrion" NARROW [GOC:TermGenie]
-synonym: "inhibition of establishment of protein localization to mitochondrion" NARROW [GOC:TermGenie]
-synonym: "negative regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "negative regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie]
-is_a: GO:1903747 ! regulation of establishment of protein localization to mitochondrion
-is_a: GO:1904950 ! negative regulation of establishment of protein localization
+def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitochondrion." [GO_REF:0000058, GOC:TermGenie, PMID:16857185]
+is_a: GO:1903747 ! regulation of protein localization to mitochondrion
+is_a: GO:1903828 ! negative regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0072655 ! establishment of protein localization to mitochondrion
-relationship: negatively_regulates GO:0072655 ! establishment of protein localization to mitochondrion
+intersection_of: negatively_regulates GO:0070585 ! protein localization to mitochondrion
+relationship: negatively_regulates GO:0070585 ! protein localization to mitochondrion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30349" xsd:anyURI
created_by: krc
creation_date: 2014-12-12T22:18:18Z
[Term]
id: GO:1903749
-name: positive regulation of establishment of protein localization to mitochondrion
+name: positive regulation of protein localization to mitochondrion
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion." [GO_REF:0000058, GOC:TermGenie, PMID:16857185]
-synonym: "activation of establishment of protein localisation to mitochondrion" NARROW [GOC:TermGenie]
-synonym: "activation of establishment of protein localization in mitochondrion" NARROW [GOC:TermGenie]
-synonym: "activation of establishment of protein localization to mitochondrion" NARROW [GOC:TermGenie]
-synonym: "positive regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "positive regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie]
-synonym: "up regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "up regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie]
-synonym: "up regulation of establishment of protein localization to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "up-regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "up-regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie]
-synonym: "up-regulation of establishment of protein localization to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "upregulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie]
-synonym: "upregulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie]
-synonym: "upregulation of establishment of protein localization to mitochondrion" EXACT [GOC:TermGenie]
+def: "Any process that activates or increases the frequency, rate or extent of protein localization to mitochondrion." [GO_REF:0000058, GOC:TermGenie, PMID:16857185]
xref: Reactome:R-HSA-114452 "Activation of BH3-only proteins"
xref: Reactome:R-HSA-75108 "Activation, myristolyation of BID and translocation to mitochondria"
-is_a: GO:1903747 ! regulation of establishment of protein localization to mitochondrion
-is_a: GO:1904951 ! positive regulation of establishment of protein localization
+is_a: GO:1903747 ! regulation of protein localization to mitochondrion
+is_a: GO:1903829 ! positive regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0072655 ! establishment of protein localization to mitochondrion
-relationship: positively_regulates GO:0072655 ! establishment of protein localization to mitochondrion
+intersection_of: positively_regulates GO:0070585 ! protein localization to mitochondrion
+relationship: positively_regulates GO:0070585 ! protein localization to mitochondrion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30349" xsd:anyURI
created_by: krc
creation_date: 2014-12-12T22:18:26Z
@@ -551669,7 +569078,6 @@
synonym: "regulation of glutathione formation" EXACT [GOC:TermGenie]
synonym: "regulation of glutathione synthesis" EXACT [GOC:TermGenie]
is_a: GO:0009889 ! regulation of biosynthetic process
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0042762 ! regulation of sulfur metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006750 ! glutathione biosynthetic process
@@ -551707,7 +569115,6 @@
synonym: "negative regulation of glutathione formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of glutathione synthesis" EXACT [GOC:TermGenie]
is_a: GO:0009890 ! negative regulation of biosynthetic process
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:1903786 ! regulation of glutathione biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006750 ! glutathione biosynthetic process
@@ -551745,7 +569152,6 @@
synonym: "upregulation of glutathione formation" EXACT [GOC:TermGenie]
synonym: "upregulation of glutathione synthesis" EXACT [GOC:TermGenie]
is_a: GO:0009891 ! positive regulation of biosynthetic process
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:1903786 ! regulation of glutathione biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006750 ! glutathione biosynthetic process
@@ -555208,10 +572614,10 @@
[Term]
id: GO:1903955
-name: positive regulation of protein targeting to mitochondrion
+name: obsolete positive regulation of protein targeting to mitochondrion
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24270810]
-comment: An example of this is PINK1 in human (UniProt symbol Q9BXM7) in PMID:24270810 inferred from mutant phenotype.
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24270810]
+comment: The reason for obsoletion is that this term was added in error. An example of this is PINK1 in human (UniProt symbol Q9BXM7) in PMID:24270810 inferred from mutant phenotype.
synonym: "activation of mitochondrial protein import" RELATED [GOC:TermGenie]
synonym: "activation of mitochondrial translocation" RELATED [GOC:TermGenie]
synonym: "activation of protein import into mitochondrion" NARROW [GOC:TermGenie]
@@ -555241,11 +572647,9 @@
synonym: "upregulation of protein targeting to mitochondria" EXACT [GOC:TermGenie]
synonym: "upregulation of protein targeting to mitochondrion" EXACT [GOC:TermGenie]
synonym: "upregulation of protein-mitochondrial targeting" EXACT [GOC:TermGenie]
-is_a: GO:1903214 ! regulation of protein targeting to mitochondrion
-is_a: GO:1903749 ! positive regulation of establishment of protein localization to mitochondrion
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0006626 ! protein targeting to mitochondrion
-relationship: positively_regulates GO:0006626 ! protein targeting to mitochondrion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30349" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:1903749
created_by: pad
creation_date: 2015-02-24T16:58:21Z
@@ -556389,8 +573793,8 @@
is_a: GO:0043465 ! regulation of fermentation
is_a: GO:0043470 ! regulation of carbohydrate catabolic process
intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0019661 ! glucose catabolic process to lactate via pyruvate
-relationship: regulates GO:0019661 ! glucose catabolic process to lactate via pyruvate
+intersection_of: regulates GO:0019661 ! homolactic fermentation
+relationship: regulates GO:0019661 ! homolactic fermentation
created_by: dph
creation_date: 2015-03-11T16:57:32Z
@@ -556439,8 +573843,8 @@
is_a: GO:1901003 ! negative regulation of fermentation
is_a: GO:1904023 ! regulation of glucose catabolic process to lactate via pyruvate
intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0019661 ! glucose catabolic process to lactate via pyruvate
-relationship: negatively_regulates GO:0019661 ! glucose catabolic process to lactate via pyruvate
+intersection_of: negatively_regulates GO:0019661 ! homolactic fermentation
+relationship: negatively_regulates GO:0019661 ! homolactic fermentation
created_by: dph
creation_date: 2015-03-11T16:57:38Z
@@ -556487,8 +573891,8 @@
is_a: GO:0010907 ! positive regulation of glucose metabolic process
is_a: GO:1904023 ! regulation of glucose catabolic process to lactate via pyruvate
intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0019661 ! glucose catabolic process to lactate via pyruvate
-relationship: positively_regulates GO:0019661 ! glucose catabolic process to lactate via pyruvate
+intersection_of: positively_regulates GO:0019661 ! homolactic fermentation
+relationship: positively_regulates GO:0019661 ! homolactic fermentation
created_by: dph
creation_date: 2015-03-11T16:57:44Z
@@ -557020,54 +574424,45 @@
[Term]
id: GO:1904051
-name: regulation of protein targeting to vacuole involved in autophagy
+name: obsolete regulation of protein targeting to vacuole involved in autophagy
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22020285]
-comment: An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype).
-is_a: GO:0033157 ! regulation of intracellular protein transport
-is_a: GO:1903335 ! regulation of vacuolar transport
-is_a: GO:1903533 ! regulation of protein targeting
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0071211 ! protein targeting to vacuole involved in autophagy
-relationship: regulates GO:0071211 ! protein targeting to vacuole involved in autophagy
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22020285]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0071211
created_by: pad
creation_date: 2015-03-17T13:54:16Z
[Term]
id: GO:1904052
-name: negative regulation of protein targeting to vacuole involved in autophagy
+name: obsolete negative regulation of protein targeting to vacuole involved in autophagy
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22020285]
-comment: An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype).
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22020285]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of protein targeting to vacuole involved in autophagy" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein targeting to vacuole involved in autophagy" EXACT [GOC:TermGenie]
synonym: "downregulation of protein targeting to vacuole involved in autophagy" EXACT [GOC:TermGenie]
synonym: "inhibition of protein targeting to vacuole involved in autophagy" NARROW [GOC:TermGenie]
-is_a: GO:0090317 ! negative regulation of intracellular protein transport
-is_a: GO:1903336 ! negative regulation of vacuolar transport
-is_a: GO:1904051 ! regulation of protein targeting to vacuole involved in autophagy
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0071211 ! protein targeting to vacuole involved in autophagy
-relationship: negatively_regulates GO:0071211 ! protein targeting to vacuole involved in autophagy
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0071211
created_by: pad
creation_date: 2015-03-17T13:54:22Z
[Term]
id: GO:1904053
-name: positive regulation of protein targeting to vacuole involved in autophagy
+name: obsolete positive regulation of protein targeting to vacuole involved in autophagy
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22020285]
-comment: An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype).
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22020285]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of protein targeting to vacuole involved in autophagy" NARROW [GOC:TermGenie]
synonym: "up regulation of protein targeting to vacuole involved in autophagy" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein targeting to vacuole involved in autophagy" EXACT [GOC:TermGenie]
synonym: "upregulation of protein targeting to vacuole involved in autophagy" EXACT [GOC:TermGenie]
-is_a: GO:0090316 ! positive regulation of intracellular protein transport
-is_a: GO:1903337 ! positive regulation of vacuolar transport
-is_a: GO:1904051 ! regulation of protein targeting to vacuole involved in autophagy
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0071211 ! protein targeting to vacuole involved in autophagy
-relationship: positively_regulates GO:0071211 ! protein targeting to vacuole involved in autophagy
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0071211
created_by: pad
creation_date: 2015-03-17T13:54:27Z
@@ -557291,9 +574686,10 @@
[Term]
id: GO:1904065
-name: G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission
+name: obsolete G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission
namespace: biological_process
-def: "Any G protein-coupled acetylcholine receptor signaling pathway that is involved in positive regulation of acetylcholine secretion, neurotransmission." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, PMID:22588719]
+def: "OBSOLETE. Any G protein-coupled acetylcholine receptor signaling pathway that is involved in positive regulation of acetylcholine secretion, neurotransmission." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, PMID:22588719]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "acetylcholine receptor signalling, muscarinic pathway involved in activation of acetylcholine secretion" NARROW [GOC:TermGenie]
synonym: "acetylcholine receptor signalling, muscarinic pathway involved in positive regulation of acetylcholine secretion, neurotransmission" EXACT [GOC:TermGenie]
synonym: "acetylcholine receptor signalling, muscarinic pathway involved in stimulation of acetylcholine secretion" NARROW [GOC:TermGenie]
@@ -557312,10 +574708,10 @@
synonym: "muscarinic acetylcholine receptor signaling pathway involved in up regulation of acetylcholine secretion" EXACT [GOC:TermGenie]
synonym: "muscarinic acetylcholine receptor signaling pathway involved in up-regulation of acetylcholine secretion" EXACT [GOC:TermGenie]
synonym: "muscarinic acetylcholine receptor signaling pathway involved in upregulation of acetylcholine secretion" EXACT [GOC:TermGenie]
-is_a: GO:0007213 ! G protein-coupled acetylcholine receptor signaling pathway
-intersection_of: GO:0007213 ! G protein-coupled acetylcholine receptor signaling pathway
-intersection_of: part_of GO:0014057 ! positive regulation of acetylcholine secretion, neurotransmission
-relationship: part_of GO:0014057 ! positive regulation of acetylcholine secretion, neurotransmission
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007213
+consider: GO:0014057
created_by: kmv
creation_date: 2015-03-19T15:28:47Z
@@ -558500,188 +575896,177 @@
[Term]
id: GO:1904127
-name: regulation of convergent extension involved in somitogenesis
+name: obsolete regulation of convergent extension involved in somitogenesis
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of convergent extension involved in somitogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
-is_a: GO:1901232 ! regulation of convergent extension involved in axis elongation
-is_a: GO:1904103 ! regulation of convergent extension involved in gastrulation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0090246 ! convergent extension involved in somitogenesis
-relationship: regulates GO:0090246 ! convergent extension involved in somitogenesis
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of convergent extension involved in somitogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0090246
created_by: dph
creation_date: 2015-04-10T21:13:04Z
[Term]
id: GO:1904128
-name: negative regulation of convergent extension involved in somitogenesis
+name: obsolete negative regulation of convergent extension involved in somitogenesis
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in somitogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in somitogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of convergent extension involved in somitogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of convergent extension involved in somitogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of convergent extension involved in somitogenesis" EXACT [GOC:TermGenie]
synonym: "inhibition of convergent extension involved in somitogenesis" NARROW [GOC:TermGenie]
-is_a: GO:1901233 ! negative regulation of convergent extension involved in axis elongation
-is_a: GO:1904104 ! negative regulation of convergent extension involved in gastrulation
-is_a: GO:1904127 ! regulation of convergent extension involved in somitogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0090246 ! convergent extension involved in somitogenesis
-relationship: negatively_regulates GO:0090246 ! convergent extension involved in somitogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0090246
created_by: dph
creation_date: 2015-04-10T21:13:10Z
[Term]
id: GO:1904129
-name: positive regulation of convergent extension involved in somitogenesis
+name: obsolete positive regulation of convergent extension involved in somitogenesis
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of convergent extension involved in somitogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of convergent extension involved in somitogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of convergent extension involved in somitogenesis" NARROW [GOC:TermGenie]
synonym: "up regulation of convergent extension involved in somitogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of convergent extension involved in somitogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of convergent extension involved in somitogenesis" EXACT [GOC:TermGenie]
-is_a: GO:1901234 ! positive regulation of convergent extension involved in axis elongation
-is_a: GO:1904105 ! positive regulation of convergent extension involved in gastrulation
-is_a: GO:1904127 ! regulation of convergent extension involved in somitogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0090246 ! convergent extension involved in somitogenesis
-relationship: positively_regulates GO:0090246 ! convergent extension involved in somitogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0090246
created_by: dph
creation_date: 2015-04-10T21:13:15Z
[Term]
id: GO:1904130
-name: regulation of convergent extension involved in neural plate elongation
+name: obsolete regulation of convergent extension involved in neural plate elongation
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of convergent extension involved in neural plate elongation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
-is_a: GO:1904103 ! regulation of convergent extension involved in gastrulation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0022007 ! convergent extension involved in neural plate elongation
-relationship: regulates GO:0022007 ! convergent extension involved in neural plate elongation
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of convergent extension involved in neural plate elongation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0022007
created_by: dph
creation_date: 2015-04-10T21:13:21Z
[Term]
id: GO:1904131
-name: negative regulation of convergent extension involved in neural plate elongation
+name: obsolete negative regulation of convergent extension involved in neural plate elongation
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in neural plate elongation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in neural plate elongation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of convergent extension involved in neural plate elongation" EXACT [GOC:TermGenie]
synonym: "down-regulation of convergent extension involved in neural plate elongation" EXACT [GOC:TermGenie]
synonym: "downregulation of convergent extension involved in neural plate elongation" EXACT [GOC:TermGenie]
synonym: "inhibition of convergent extension involved in neural plate elongation" NARROW [GOC:TermGenie]
-is_a: GO:1904104 ! negative regulation of convergent extension involved in gastrulation
-is_a: GO:1904130 ! regulation of convergent extension involved in neural plate elongation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0022007 ! convergent extension involved in neural plate elongation
-relationship: negatively_regulates GO:0022007 ! convergent extension involved in neural plate elongation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0022007
created_by: dph
creation_date: 2015-04-10T21:13:27Z
[Term]
id: GO:1904132
-name: positive regulation of convergent extension involved in neural plate elongation
+name: obsolete positive regulation of convergent extension involved in neural plate elongation
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of convergent extension involved in neural plate elongation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of convergent extension involved in neural plate elongation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of convergent extension involved in neural plate elongation" NARROW [GOC:TermGenie]
synonym: "up regulation of convergent extension involved in neural plate elongation" EXACT [GOC:TermGenie]
synonym: "up-regulation of convergent extension involved in neural plate elongation" EXACT [GOC:TermGenie]
synonym: "upregulation of convergent extension involved in neural plate elongation" EXACT [GOC:TermGenie]
-is_a: GO:1904105 ! positive regulation of convergent extension involved in gastrulation
-is_a: GO:1904130 ! regulation of convergent extension involved in neural plate elongation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0022007 ! convergent extension involved in neural plate elongation
-relationship: positively_regulates GO:0022007 ! convergent extension involved in neural plate elongation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0022007
created_by: dph
creation_date: 2015-04-10T21:13:33Z
[Term]
id: GO:1904133
-name: regulation of convergent extension involved in rhombomere morphogenesis
+name: obsolete regulation of convergent extension involved in rhombomere morphogenesis
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
-is_a: GO:1904103 ! regulation of convergent extension involved in gastrulation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:1904125 ! convergent extension involved in rhombomere morphogenesis
-relationship: regulates GO:1904125 ! convergent extension involved in rhombomere morphogenesis
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:1904125
created_by: dph
creation_date: 2015-04-10T21:21:12Z
[Term]
id: GO:1904134
-name: negative regulation of convergent extension involved in rhombomere morphogenesis
+name: obsolete negative regulation of convergent extension involved in rhombomere morphogenesis
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of convergent extension involved in rhombomere morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of convergent extension involved in rhombomere morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of convergent extension involved in rhombomere morphogenesis" EXACT [GOC:TermGenie]
synonym: "inhibition of convergent extension involved in rhombomere morphogenesis" NARROW [GOC:TermGenie]
-is_a: GO:1904104 ! negative regulation of convergent extension involved in gastrulation
-is_a: GO:1904133 ! regulation of convergent extension involved in rhombomere morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:1904125 ! convergent extension involved in rhombomere morphogenesis
-relationship: negatively_regulates GO:1904125 ! convergent extension involved in rhombomere morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:1904125
created_by: dph
creation_date: 2015-04-10T21:21:18Z
[Term]
id: GO:1904135
-name: positive regulation of convergent extension involved in rhombomere morphogenesis
+name: obsolete positive regulation of convergent extension involved in rhombomere morphogenesis
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of convergent extension involved in rhombomere morphogenesis" NARROW [GOC:TermGenie]
synonym: "up regulation of convergent extension involved in rhombomere morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of convergent extension involved in rhombomere morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of convergent extension involved in rhombomere morphogenesis" EXACT [GOC:TermGenie]
-is_a: GO:1904105 ! positive regulation of convergent extension involved in gastrulation
-is_a: GO:1904133 ! regulation of convergent extension involved in rhombomere morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:1904125 ! convergent extension involved in rhombomere morphogenesis
-relationship: positively_regulates GO:1904125 ! convergent extension involved in rhombomere morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:1904125
created_by: dph
creation_date: 2015-04-10T21:21:24Z
[Term]
id: GO:1904136
-name: regulation of convergent extension involved in notochord morphogenesis
+name: obsolete regulation of convergent extension involved in notochord morphogenesis
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of convergent extension involved in notochord morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
-is_a: GO:1904103 ! regulation of convergent extension involved in gastrulation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:1904126 ! convergent extension involved in notochord morphogenesis
-relationship: regulates GO:1904126 ! convergent extension involved in notochord morphogenesis
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of convergent extension involved in notochord morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:1904126
created_by: dph
creation_date: 2015-04-10T21:21:30Z
[Term]
id: GO:1904137
-name: negative regulation of convergent extension involved in notochord morphogenesis
+name: obsolete negative regulation of convergent extension involved in notochord morphogenesis
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in notochord morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in notochord morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of convergent extension involved in notochord morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of convergent extension involved in notochord morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of convergent extension involved in notochord morphogenesis" EXACT [GOC:TermGenie]
synonym: "inhibition of convergent extension involved in notochord morphogenesis" NARROW [GOC:TermGenie]
-is_a: GO:1904104 ! negative regulation of convergent extension involved in gastrulation
-is_a: GO:1904136 ! regulation of convergent extension involved in notochord morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:1904126 ! convergent extension involved in notochord morphogenesis
-relationship: negatively_regulates GO:1904126 ! convergent extension involved in notochord morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:1904126
created_by: dph
creation_date: 2015-04-10T21:21:36Z
[Term]
id: GO:1904138
-name: positive regulation of convergent extension involved in notochord morphogenesis
+name: obsolete positive regulation of convergent extension involved in notochord morphogenesis
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of convergent extension involved in notochord morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of convergent extension involved in notochord morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of convergent extension involved in notochord morphogenesis" NARROW [GOC:TermGenie]
synonym: "up regulation of convergent extension involved in notochord morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of convergent extension involved in notochord morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of convergent extension involved in notochord morphogenesis" EXACT [GOC:TermGenie]
-is_a: GO:1904105 ! positive regulation of convergent extension involved in gastrulation
-is_a: GO:1904136 ! regulation of convergent extension involved in notochord morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:1904126 ! convergent extension involved in notochord morphogenesis
-relationship: positively_regulates GO:1904126 ! convergent extension involved in notochord morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:1904126
created_by: dph
creation_date: 2015-04-10T21:21:41Z
@@ -559837,7 +577222,6 @@
synonym: "membrane protein proteolysis involved in protein retrotranslocation, ER to cytosol" EXACT [GOC:TermGenie]
synonym: "membrane protein proteolysis involved in retrograde protein transport, endoplasmic reticulum to cytosol" EXACT [GOC:TermGenie]
is_a: GO:0033619 ! membrane protein proteolysis
-is_a: GO:0051603 ! proteolysis involved in protein catabolic process
intersection_of: GO:0033619 ! membrane protein proteolysis
intersection_of: part_of GO:0030970 ! retrograde protein transport, ER to cytosol
relationship: part_of GO:0030970 ! retrograde protein transport, ER to cytosol
@@ -561866,51 +579250,48 @@
[Term]
id: GO:1904259
-name: regulation of basement membrane assembly involved in embryonic body morphogenesis
+name: obsolete regulation of basement membrane assembly involved in embryonic body morphogenesis
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23940118]
-is_a: GO:0045995 ! regulation of embryonic development
-is_a: GO:0110011 ! regulation of basement membrane organization
-is_a: GO:1901201 ! regulation of extracellular matrix assembly
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:2001197 ! basement membrane assembly involved in embryonic body morphogenesis
-relationship: regulates GO:2001197 ! basement membrane assembly involved in embryonic body morphogenesis
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23940118]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0010172
+consider: GO:1901201
created_by: als
creation_date: 2015-05-21T09:20:43Z
[Term]
id: GO:1904260
-name: negative regulation of basement membrane assembly involved in embryonic body morphogenesis
+name: obsolete negative regulation of basement membrane assembly involved in embryonic body morphogenesis
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23940118]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23940118]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of basement membrane assembly involved in embryonic body morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of basement membrane assembly involved in embryonic body morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of basement membrane assembly involved in embryonic body morphogenesis" EXACT [GOC:TermGenie]
synonym: "inhibition of basement membrane assembly involved in embryonic body morphogenesis" NARROW [GOC:TermGenie]
-is_a: GO:0051093 ! negative regulation of developmental process
-is_a: GO:1901202 ! negative regulation of extracellular matrix assembly
-is_a: GO:1904259 ! regulation of basement membrane assembly involved in embryonic body morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:2001197 ! basement membrane assembly involved in embryonic body morphogenesis
-relationship: negatively_regulates GO:2001197 ! basement membrane assembly involved in embryonic body morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0010172
+consider: GO:1901202
created_by: als
creation_date: 2015-05-21T09:20:49Z
[Term]
id: GO:1904261
-name: positive regulation of basement membrane assembly involved in embryonic body morphogenesis
+name: obsolete positive regulation of basement membrane assembly involved in embryonic body morphogenesis
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23940118]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23940118]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of basement membrane assembly involved in embryonic body morphogenesis" NARROW [GOC:TermGenie]
synonym: "up regulation of basement membrane assembly involved in embryonic body morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of basement membrane assembly involved in embryonic body morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of basement membrane assembly involved in embryonic body morphogenesis" EXACT [GOC:TermGenie]
-is_a: GO:0051094 ! positive regulation of developmental process
-is_a: GO:1901203 ! positive regulation of extracellular matrix assembly
-is_a: GO:1904259 ! regulation of basement membrane assembly involved in embryonic body morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:2001197 ! basement membrane assembly involved in embryonic body morphogenesis
-relationship: positively_regulates GO:2001197 ! basement membrane assembly involved in embryonic body morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0010172
+consider: GO:1901203
created_by: als
creation_date: 2015-05-21T09:20:55Z
@@ -562587,50 +579968,45 @@
[Term]
id: GO:1904301
-name: regulation of maternal process involved in parturition
+name: obsolete regulation of maternal process involved in parturition
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of maternal process involved in parturition." [GO_REF:0000058, GOC:TermGenie, PMID:1849751]
-is_a: GO:0051239 ! regulation of multicellular organismal process
-is_a: GO:2000241 ! regulation of reproductive process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0060137 ! maternal process involved in parturition
-relationship: regulates GO:0060137 ! maternal process involved in parturition
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of maternal process involved in parturition." [GO_REF:0000058, GOC:TermGenie, PMID:1849751]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007567
created_by: sl
creation_date: 2015-06-09T23:01:32Z
[Term]
id: GO:1904302
-name: negative regulation of maternal process involved in parturition
+name: obsolete negative regulation of maternal process involved in parturition
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of maternal process involved in parturition." [GO_REF:0000058, GOC:TermGenie, PMID:1849751]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of maternal process involved in parturition." [GO_REF:0000058, GOC:TermGenie, PMID:1849751]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of maternal process involved in parturition" EXACT [GOC:TermGenie]
synonym: "down-regulation of maternal process involved in parturition" EXACT [GOC:TermGenie]
synonym: "downregulation of maternal process involved in parturition" EXACT [GOC:TermGenie]
synonym: "inhibition of maternal process involved in parturition" NARROW [GOC:TermGenie]
-is_a: GO:0051241 ! negative regulation of multicellular organismal process
-is_a: GO:1904301 ! regulation of maternal process involved in parturition
-is_a: GO:2000242 ! negative regulation of reproductive process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0060137 ! maternal process involved in parturition
-relationship: negatively_regulates GO:0060137 ! maternal process involved in parturition
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007567
created_by: sl
creation_date: 2015-06-09T23:01:38Z
[Term]
id: GO:1904303
-name: positive regulation of maternal process involved in parturition
+name: obsolete positive regulation of maternal process involved in parturition
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of maternal process involved in parturition." [GO_REF:0000058, GOC:TermGenie, PMID:1849751]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of maternal process involved in parturition." [GO_REF:0000058, GOC:TermGenie, PMID:1849751]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of maternal process involved in parturition" NARROW [GOC:TermGenie]
synonym: "up regulation of maternal process involved in parturition" EXACT [GOC:TermGenie]
synonym: "up-regulation of maternal process involved in parturition" EXACT [GOC:TermGenie]
synonym: "upregulation of maternal process involved in parturition" EXACT [GOC:TermGenie]
-is_a: GO:0051240 ! positive regulation of multicellular organismal process
-is_a: GO:1904301 ! regulation of maternal process involved in parturition
-is_a: GO:2000243 ! positive regulation of reproductive process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0060137 ! maternal process involved in parturition
-relationship: positively_regulates GO:0060137 ! maternal process involved in parturition
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007567
created_by: sl
creation_date: 2015-06-09T23:01:45Z
@@ -562808,25 +580184,25 @@
[Term]
id: GO:1904318
-name: regulation of smooth muscle contraction involved in micturition
+name: obsolete regulation of smooth muscle contraction involved in micturition
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
-is_a: GO:0006940 ! regulation of smooth muscle contraction
-is_a: GO:0044062 ! regulation of excretion
-is_a: GO:0098801 ! regulation of renal system process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0060083 ! smooth muscle contraction involved in micturition
-relationship: regulates GO:0060083 ! smooth muscle contraction involved in micturition
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0006940
+consider: GO:0060073
created_by: sl
creation_date: 2015-06-10T18:46:11Z
[Term]
id: GO:1904319
-name: negative regulation of smooth muscle contraction involved in micturition
+name: obsolete negative regulation of smooth muscle contraction involved in micturition
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie]
synonym: "down regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "down regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
@@ -562841,19 +580217,18 @@
synonym: "inhibition of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
synonym: "negative regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "negative regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
-is_a: GO:0045986 ! negative regulation of smooth muscle contraction
-is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0060083 ! smooth muscle contraction involved in micturition
-relationship: negatively_regulates GO:0060083 ! smooth muscle contraction involved in micturition
-created_by: sl
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0045986
+consider: GO:0060073
creation_date: 2015-06-10T18:46:17Z
[Term]
id: GO:1904320
-name: positive regulation of smooth muscle contraction involved in micturition
+name: obsolete positive regulation of smooth muscle contraction involved in micturition
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of smooth muscle contraction involved in micturition" NARROW [GOC:TermGenie]
synonym: "activation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "activation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
@@ -562868,11 +580243,10 @@
synonym: "upregulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie]
synonym: "upregulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "upregulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
-is_a: GO:0045987 ! positive regulation of smooth muscle contraction
-is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0060083 ! smooth muscle contraction involved in micturition
-relationship: positively_regulates GO:0060083 ! smooth muscle contraction involved in micturition
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0045987
+consider: GO:0060073
created_by: sl
creation_date: 2015-06-10T18:46:23Z
@@ -563885,20 +581259,12 @@
[Term]
id: GO:1904378
-name: maintenance of unfolded protein involved in ERAD pathway
+name: obsolete maintenance of unfolded protein involved in ERAD pathway
namespace: biological_process
-def: "Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome." [GO_REF:0000060, GOC:bf, GOC:BHF, GOC:nc, GOC:PARL, GOC:TermGenie, PMID:21636303]
-synonym: "chaperone holdase activity" RELATED [PMID:23417671]
-synonym: "ERAD chaperone-like activity" RELATED [GOC:bf]
-synonym: "holdase activity" RELATED [PMID:21636303]
-synonym: "maintenance of unfolded protein during ERAD" RELATED [GOC:bf]
-synonym: "maintenance of unfolded protein involved in endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie]
-synonym: "maintenance of unfolded protein involved in endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie]
-synonym: "maintenance of unfolded protein involved in ER-associated degradation pathway" RELATED [GOC:TermGenie]
-is_a: GO:0036506 ! maintenance of unfolded protein
-intersection_of: GO:0036506 ! maintenance of unfolded protein
-intersection_of: part_of GO:0036503 ! ERAD pathway
-relationship: part_of GO:0036503 ! ERAD pathway
+def: "OBSOLETE. Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome." [GO_REF:0000060, GOC:bf, GOC:BHF, GOC:nc, GOC:PARL, GOC:TermGenie, PMID:21636303]
+comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30977" xsd:anyURI
+is_obsolete: true
created_by: bf
creation_date: 2015-06-23T09:21:53Z
@@ -564067,7 +581433,7 @@
name: response to ciliary neurotrophic factor
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16914133]
-is_a: GO:1901698 ! response to nitrogen compound
+is_a: GO:0042221 ! response to chemical
created_by: sl
creation_date: 2015-06-23T19:13:04Z
@@ -564076,7 +581442,7 @@
name: cellular response to ciliary neurotrophic factor
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16914133]
-is_a: GO:1901699 ! cellular response to nitrogen compound
+is_a: GO:0070887 ! cellular response to chemical stimulus
is_a: GO:1904391 ! response to ciliary neurotrophic factor
created_by: sl
creation_date: 2015-06-23T19:13:10Z
@@ -564343,7 +581709,7 @@
name: melatonin binding
namespace: molecular_function
def: "Binding to melatonin." [GO_REF:0000067, GOC:mr, GOC:TermGenie, PMID:10379923]
-is_a: GO:0033218 ! amide binding
+is_a: GO:0005488 ! binding
created_by: mr
creation_date: 2015-06-25T19:19:53Z
@@ -567623,7 +584989,6 @@
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14597422]
synonym: "response to glycoproteins" EXACT []
-is_a: GO:1901698 ! response to nitrogen compound
is_a: GO:1901700 ! response to oxygen-containing compound
created_by: sl
creation_date: 2015-08-20T16:46:24Z
@@ -567634,7 +584999,6 @@
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14597422]
synonym: "cellular response to glycoproteins" EXACT []
-is_a: GO:1901699 ! cellular response to nitrogen compound
is_a: GO:1901701 ! cellular response to oxygen-containing compound
is_a: GO:1904587 ! response to glycoprotein
created_by: sl
@@ -568998,9 +586362,10 @@
[Term]
id: GO:1904671
-name: negative regulation of cell differentiation involved in stem cell population maintenance
+name: obsolete negative regulation of cell differentiation involved in stem cell population maintenance
namespace: biological_process
-def: "Any negative regulation of cell differentiation that is involved in stem cell population maintenance." [GO_REF:0000060, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607]
+def: "OBSOLETE. Any negative regulation of cell differentiation that is involved in stem cell population maintenance." [GO_REF:0000060, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "down regulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie]
synonym: "down-regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie]
@@ -569010,10 +586375,10 @@
synonym: "inhibition of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "inhibition of cell differentiation involved in stem cell population maintenance" NARROW [GOC:TermGenie]
synonym: "negative regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie]
-is_a: GO:0045596 ! negative regulation of cell differentiation
-intersection_of: GO:0045596 ! negative regulation of cell differentiation
-intersection_of: part_of GO:0019827 ! stem cell population maintenance
-relationship: part_of GO:0019827 ! stem cell population maintenance
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0019827
+consider: GO:0045596
created_by: tb
creation_date: 2015-09-12T00:46:08Z
@@ -571540,8 +588905,6 @@
name: all-trans-retinol binding
namespace: molecular_function
def: "Binding to all-trans-retinol." [GO_REF:0000067, GOC:kmv, GOC:TermGenie, PMID:19828452]
-xref: Reactome:R-HSA-2404135 "RBP4 binds atROL"
-xref: Reactome:R-HSA-975633 "atROL binds to RBP2"
is_a: GO:0019841 ! retinol binding
created_by: kmv
creation_date: 2015-10-27T21:14:47Z
@@ -571984,10 +589347,10 @@
[Term]
id: GO:1904786
-name: negative regulation of asymmetric protein localization involved in cell fate determination
+name: obsolete negative regulation of asymmetric protein localization involved in cell fate determination
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of asymmetric protein localization involved in cell fate determination." [GO_REF:0000058, GOC:TermGenie, PMID:17476329]
-comment: wrm-1 in C. Elegans (Q10953) in PMID:17476329 (IMP)
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of asymmetric protein localization involved in cell fate determination." [GO_REF:0000058, GOC:TermGenie, PMID:17476329]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of asymmetric protein localisation involved in cell fate determination" EXACT [GOC:TermGenie]
synonym: "down regulation of asymmetric protein localization involved in cell fate commitment" EXACT [GOC:TermGenie]
synonym: "down regulation of asymmetric protein localization involved in cell fate determination" EXACT [GOC:TermGenie]
@@ -572012,11 +589375,10 @@
synonym: "negative regulation of asymmetric protein localization involved in cell fate commitment" EXACT [GOC:TermGenie]
synonym: "negative regulation of asymmetric protein localization resulting in cell fate commitment" EXACT [GOC:TermGenie]
synonym: "negative regulation of cell fate commitment, asymmetric protein localization" EXACT [GOC:TermGenie]
-is_a: GO:1903828 ! negative regulation of protein localization
-is_a: GO:1904785 ! regulation of asymmetric protein localization involved in cell fate determination
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0045167 ! asymmetric protein localization involved in cell fate determination
-relationship: negatively_regulates GO:0045167 ! asymmetric protein localization involved in cell fate determination
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001709
+consider: GO:0032880
created_by: es
creation_date: 2015-11-03T12:11:13Z
@@ -577463,14 +594825,14 @@
[Term]
id: GO:1905038
-name: regulation of membrane lipid metabolic process
+name: obsolete regulation of membrane lipid metabolic process
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of membrane lipid metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:25954280]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of membrane lipid metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:25954280]
+comment: The reason for obsoletion is that this term regulates GO:0006643, which has been obsoleted.
synonym: "regulation of membrane lipid metabolism" EXACT [GOC:TermGenie]
-is_a: GO:0019216 ! regulation of lipid metabolic process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0006643 ! membrane lipid metabolic process
-relationship: regulates GO:0006643 ! membrane lipid metabolic process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26698" xsd:anyURI
+is_obsolete: true
+replaced_by: GO:0019216
created_by: tb
creation_date: 2016-03-08T20:41:32Z
@@ -577741,30 +595103,30 @@
[Term]
id: GO:1905054
-name: calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium ion concentration
+name: obsolete calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium ion concentration
namespace: molecular_function
-def: "Any calcium-induced calcium release activity that is involved in regulation of presynaptic cytosolic calcium ion concentration." [GO_REF:0000061, GOC:TermGenie, PMID:15919193, PMID:23918386]
-subset: goslim_synapse
+def: "OBSOLETE. Any calcium-induced calcium release activity that is involved in regulation of presynaptic cytosolic calcium ion concentration." [GO_REF:0000061, GOC:TermGenie, PMID:15919193, PMID:23918386]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium levels" EXACT syngo_official_label []
-is_a: GO:0048763 ! calcium-induced calcium release activity
-intersection_of: GO:0048763 ! calcium-induced calcium release activity
-intersection_of: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration
-relationship: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0048763
+consider: GO:0099509
created_by: dos
creation_date: 2016-03-17T12:12:53Z
[Term]
id: GO:1905055
-name: calcium:monoatomic cation antiporter activity involved in regulation of presynaptic cytosolic calcium ion concentration
+name: obsolete calcium:monoatomic cation antiporter activity involved in regulation of presynaptic cytosolic calcium ion concentration
namespace: molecular_function
-def: "Any calcium:cation antiporter activity that is involved in regulation of presynaptic cytosolic calcium ion concentration." [GO_REF:0000061, GOC:TermGenie, PMID:22972962, PMID:23255722]
-subset: goslim_synapse
+def: "OBSOLETE. Any calcium:cation antiporter activity that is involved in regulation of presynaptic cytosolic calcium ion concentration." [GO_REF:0000061, GOC:TermGenie, PMID:22972962, PMID:23255722]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "calcium ion antiporter activity involved in regulation of presynaptic cytosolic calcium levels" EXACT syngo_official_label []
synonym: "calcium:cation antiporter activity involved in regulation of presynaptic cytosolic calcium ion concentration" BROAD []
-is_a: GO:0015368 ! calcium:monoatomic cation antiporter activity
-intersection_of: GO:0015368 ! calcium:monoatomic cation antiporter activity
-intersection_of: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration
-relationship: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0015368
+consider: GO:0099509
created_by: dos
creation_date: 2016-03-17T14:35:35Z
@@ -577794,10 +595156,10 @@
[Term]
id: GO:1905057
-name: voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels
+name: obsolete voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels
namespace: molecular_function
-def: "Any voltage-gated calcium channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration." [GO_REF:0000061, GOC:TermGenie, PMID:20734177]
-subset: goslim_synapse
+def: "OBSOLETE. Any voltage-gated calcium channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration." [GO_REF:0000061, GOC:TermGenie, PMID:20734177]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "depolarization-activated voltage gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie]
synonym: "depolarization-activated voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie]
synonym: "depolarization-activated voltage-gated calcium channel involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie]
@@ -577807,10 +595169,10 @@
synonym: "voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels" EXACT syngo_official_label []
synonym: "voltage-gated calcium ion channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie]
synonym: "voltage-sensitive calcium channel involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie]
-is_a: GO:0099511 ! voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels
-intersection_of: GO:0005245 ! voltage-gated calcium channel activity
-intersection_of: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration
-relationship: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0005245
+consider: GO:0099566
created_by: dos
creation_date: 2016-03-18T12:31:48Z
@@ -579252,7 +596614,6 @@
namespace: biological_process
def: "The directed movement of carcinine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:dph, GOC:TermGenie, PMID:26653853, PMID:26713872]
is_a: GO:0015695 ! organic cation transport
-is_a: GO:0042886 ! amide transport
is_a: GO:0045117 ! azole transmembrane transport
is_a: GO:0072337 ! modified amino acid transport
is_a: GO:0098739 ! import across plasma membrane
@@ -579264,7 +596625,6 @@
name: carcinine transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of carcinine from one side of a membrane to the other." [GO_REF:0000070, GOC:dph, GOC:TermGenie, PMID:26653853, PMID:26713872]
-is_a: GO:0042887 ! amide transmembrane transporter activity
is_a: GO:0072349 ! modified amino acid transmembrane transporter activity
is_a: GO:1901474 ! azole transmembrane transporter activity
created_by: dph
@@ -579367,7 +596727,7 @@
synonym: "dethiobiotin import" RELATED []
synonym: "dethiobiotin import into cell" EXACT []
is_a: GO:0015718 ! monocarboxylic acid transport
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
is_a: GO:0098739 ! import across plasma membrane
is_a: GO:1905039 ! carboxylic acid transmembrane transport
created_by: jl
@@ -580538,14 +597898,15 @@
[Term]
id: GO:1905197
-name: endocannabinoid signaling pathway involved in retrograde trans-synaptic signaling
+name: obsolete endocannabinoid signaling pathway involved in retrograde trans-synaptic signaling
namespace: biological_process
-def: "Any endocannabinoid signaling pathway that is involved in retrograde trans-synaptic signaling by endocannabinoid." [GO_REF:0000060, GOC:TermGenie, PMID:23040807]
+def: "OBSOLETE. Any endocannabinoid signaling pathway that is involved in retrograde trans-synaptic signaling by endocannabinoid." [GO_REF:0000060, GOC:TermGenie, PMID:23040807]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "endocannabinoid signalling pathway involved in retrograde trans-synaptic signaling by endocannabinoid" EXACT [GOC:TermGenie]
-is_a: GO:1905129 ! endocannabinoid signaling pathway involved in trans-synaptic signaling
-intersection_of: GO:0071926 ! endocannabinoid signaling pathway
-intersection_of: part_of GO:0098921 ! retrograde trans-synaptic signaling by endocannabinoid
-relationship: part_of GO:0098921 ! retrograde trans-synaptic signaling by endocannabinoid
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0071926
+consider: GO:0098921
created_by: dos
creation_date: 2016-05-12T14:29:38Z
@@ -581964,9 +599325,10 @@
[Term]
id: GO:1905283
-name: negative regulation of epidermal growth factor receptor signaling pathway involved in heart process
+name: obsolete negative regulation of epidermal growth factor receptor signaling pathway involved in heart process
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie]
synonym: "down regulation of EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie]
synonym: "down regulation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie]
@@ -582036,20 +599398,18 @@
synonym: "negative regulation of ERBB1 signaling pathway involved in heart process" EXACT [GOC:TermGenie]
synonym: "negative regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie]
synonym: "negative regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" EXACT [GOC:TermGenie]
-is_a: GO:0042059 ! negative regulation of epidermal growth factor receptor signaling pathway
-is_a: GO:0051241 ! negative regulation of multicellular organismal process
-is_a: GO:1905282 ! regulation of epidermal growth factor receptor signaling pathway involved in heart process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:1905251 ! epidermal growth factor receptor signaling pathway involved in heart process
-relationship: negatively_regulates GO:1905251 ! epidermal growth factor receptor signaling pathway involved in heart process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0042059
created_by: bc
creation_date: 2016-06-20T14:40:49Z
[Term]
id: GO:1905284
-name: positive regulation of epidermal growth factor receptor signaling pathway involved in heart process
+name: obsolete positive regulation of epidermal growth factor receptor signaling pathway involved in heart process
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "activation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie]
synonym: "activation of EGF receptor signaling pathway involved in heart process" NARROW [GOC:TermGenie]
synonym: "activation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie]
@@ -582119,12 +599479,9 @@
synonym: "upregulation of ERBB1 signaling pathway involved in heart process" EXACT [GOC:TermGenie]
synonym: "upregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie]
synonym: "upregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" EXACT [GOC:TermGenie]
-is_a: GO:0045742 ! positive regulation of epidermal growth factor receptor signaling pathway
-is_a: GO:0051240 ! positive regulation of multicellular organismal process
-is_a: GO:1905282 ! regulation of epidermal growth factor receptor signaling pathway involved in heart process
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:1905251 ! epidermal growth factor receptor signaling pathway involved in heart process
-relationship: positively_regulates GO:1905251 ! epidermal growth factor receptor signaling pathway involved in heart process
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0045742
created_by: bc
creation_date: 2016-06-20T14:40:57Z
@@ -582570,18 +599927,17 @@
[Term]
id: GO:1905311
-name: negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
+name: obsolete negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "inhibition of cardiac neural crest cell migration involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
-is_a: GO:0030336 ! negative regulation of cell migration
-is_a: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis
-relationship: negatively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003253
created_by: rl
creation_date: 2016-07-11T17:34:35Z
@@ -585221,7 +602577,7 @@
name: microcystin transport
namespace: biological_process
def: "The directed movement of a microcystin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GO_REF:0000065, GOC:TermGenie, PMID:26055554]
-is_a: GO:0042886 ! amide transport
+is_a: GO:0071705 ! nitrogen compound transport
created_by: cvs
creation_date: 2016-09-13T23:15:51Z
@@ -588204,7 +605560,6 @@
synonym: "regulation of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie]
synonym: "regulation of ferrichrome formation" EXACT [GOC:TermGenie]
synonym: "regulation of ferrichrome synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:1900704 ! regulation of siderophore biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0031169 ! ferrichrome biosynthetic process
@@ -588251,7 +605606,6 @@
synonym: "negative regulation of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie]
synonym: "negative regulation of ferrichrome formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of ferrichrome synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:1900705 ! negative regulation of siderophore biosynthetic process
is_a: GO:1905568 ! regulation of ferrichrome biosynthetic process
intersection_of: GO:0065007 ! biological regulation
@@ -588299,7 +605653,6 @@
synonym: "upregulation of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie]
synonym: "upregulation of ferrichrome formation" EXACT [GOC:TermGenie]
synonym: "upregulation of ferrichrome synthesis" EXACT [GOC:TermGenie]
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:1900706 ! positive regulation of siderophore biosynthetic process
is_a: GO:1905568 ! regulation of ferrichrome biosynthetic process
intersection_of: GO:0065007 ! biological regulation
@@ -590923,9 +608276,7 @@
synonym: "regulation of shmoo orientation" NARROW [GOC:TermGenie]
synonym: "regulation of shmooing" NARROW [GOC:TermGenie]
is_a: GO:0022604 ! regulation of cell morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0000753 ! cell morphogenesis involved in conjugation with cellular fusion
-relationship: regulates GO:0000753 ! cell morphogenesis involved in conjugation with cellular fusion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
created_by: mah
creation_date: 2016-11-18T11:33:54Z
@@ -591242,16 +608593,16 @@
[Term]
id: GO:1905741
-name: calcium export from the mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration
+name: obsolete calcium export from the mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration
namespace: biological_process
-def: "Any mitochondrial calcium release that is involved in positive regulation of presynaptic cytosolic calcium concentration." [GO_REF:0000060, GOC:TermGenie, PMID:26644474]
+def: "OBSOLETE. Any mitochondrial calcium release that is involved in positive regulation of presynaptic cytosolic calcium concentration." [GO_REF:0000060, GOC:TermGenie, PMID:26644474]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "calcium ion transmembrane export from mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration" EXACT [GOC:TermGenie]
synonym: "mitochondrial calcium release involved in positive regulation of presynaptic cytosolic calcium concentration" EXACT []
-is_a: GO:0051649 ! establishment of localization in cell
-is_a: GO:0099093 ! calcium export from the mitochondrion
-intersection_of: GO:0099093 ! calcium export from the mitochondrion
-intersection_of: part_of GO:0099533 ! positive regulation of presynaptic cytosolic calcium concentration
-relationship: part_of GO:0099533 ! positive regulation of presynaptic cytosolic calcium concentration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0099093
+consider: GO:0099533
created_by: dos
creation_date: 2016-12-06T10:05:01Z
@@ -591266,17 +608617,16 @@
[Term]
id: GO:1905743
-name: calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration
+name: obsolete calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration
namespace: biological_process
-def: "Any mitochondrial calcium uptake that is involved in negative regulation of presynaptic cytosolic calcium concentration." [GO_REF:0000060, GOC:TermGenie, PMID:26644474]
-subset: goslim_synapse
+def: "OBSOLETE. Any mitochondrial calcium uptake that is involved in negative regulation of presynaptic cytosolic calcium concentration." [GO_REF:0000060, GOC:TermGenie, PMID:26644474]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "calcium ion transmembrane import into mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration" EXACT [GOC:TermGenie]
synonym: "mitochondrial calcium uptake involved in negative regulation of presynaptic cytosolic calcium concentration" EXACT []
-is_a: GO:0036444 ! calcium import into the mitochondrion
-is_a: GO:0051649 ! establishment of localization in cell
-intersection_of: GO:0036444 ! calcium import into the mitochondrion
-intersection_of: part_of GO:0099113 ! negative regulation of presynaptic cytosolic calcium concentration
-relationship: part_of GO:0099113 ! negative regulation of presynaptic cytosolic calcium concentration
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0036444
+consider: GO:0099113
created_by: dos
creation_date: 2016-12-06T10:53:17Z
@@ -595306,7 +612656,9 @@
is_a: GO:0001409 ! guanine nucleotide transmembrane transporter activity
is_a: GO:0005346 ! purine ribonucleotide transmembrane transporter activity
is_a: GO:0140359 ! ABC-type transporter activity
+property_value: skos:exactMatch RHEA:66188
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27278" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: ha
creation_date: 2017-02-16T15:54:51Z
@@ -595553,7 +612905,9 @@
xref: MetaCyc:RXN0-4281
xref: RHEA:27986
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+property_value: skos:exactMatch RHEA:27986
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27180" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-12-05T15:55:06Z
@@ -595571,6 +612925,9 @@
xref: Reactome:R-HSA-2509816 "NUDT16 hydrolyses IDP to IMP"
xref: RHEA:35207
is_a: GO:0017110 ! nucleoside diphosphate phosphatase activity
+property_value: skos:exactMatch EC:3.6.1.64
+property_value: skos:exactMatch RHEA:35207
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2012-12-05T16:46:52Z
@@ -596115,6 +613472,7 @@
namespace: molecular_function
def: "Catalysis of the reaction: DNA containing 5-methylcytosine + H2O = DNA with abasic site + 5-methylcytosine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the DNA 5-methylcytosine and the deoxyribose sugar to remove the 5-methylcytosine, leaving an abasic site." [PMID:23316050]
is_a: GO:0003905 ! alkylbase DNA N-glycosylase activity
+property_value: skos:broadMatch EC:3.2.2.21
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: tb
creation_date: 2013-02-22T01:09:06Z
@@ -596141,7 +613499,10 @@
xref: MetaCyc:RXN-8990
xref: RHEA:55532
is_a: GO:0016831 ! carboxy-lyase activity
+property_value: skos:exactMatch EC:4.1.1.109
+property_value: skos:exactMatch RHEA:55532
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28523" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30815" xsd:anyURI
created_by: tb
creation_date: 2013-02-25T20:22:35Z
@@ -596357,13 +613718,14 @@
[Term]
id: GO:1990076
-name: cell wall polysaccharide catabolic process involved in abscission
+name: obsolete cell wall polysaccharide catabolic process involved in abscission
namespace: biological_process
-def: "Any cell wall polysaccharide catabolic process that is involved in abscission." [GOC:TermGenie, PMID:23479623]
-is_a: GO:0044347 ! cell wall polysaccharide catabolic process
-intersection_of: GO:0044347 ! cell wall polysaccharide catabolic process
-intersection_of: part_of GO:0009838 ! abscission
-relationship: part_of GO:0009838 ! abscission
+def: "OBSOLETE. Any cell wall polysaccharide catabolic process that is involved in abscission." [GOC:TermGenie, PMID:23479623]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0009838
+consider: GO:0044347
created_by: dhl
creation_date: 2013-04-25T16:29:43Z
@@ -596471,10 +613833,10 @@
[Term]
id: GO:1990088
-name: [methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase
+name: [methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity
namespace: molecular_function
alt_id: GO:0043851
-def: "Catalysis of the reaction: a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-coenzyme M + a [Co(I) methanol-specific corrinoid protein] + H+." [GOC:hjd, PMID:10077852, RHEA:45208]
+def: "Catalysis of the reaction: a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-coenzyme M + a [Co(I) methanol-specific corrinoid protein] + H+." [PMID:10077852, RHEA:45208]
comment: This function is the second step in the pathway of methanogenesis from methanol.
synonym: "methanol-specific methylcobalamin: coenzyme M methyltransferase activity" EXACT []
synonym: "methanol-specific methylcobalamin:coenzyme M methyltransferase activity" EXACT []
@@ -596485,7 +613847,10 @@
xref: MetaCyc:RXN-8096
xref: RHEA:45208
is_a: GO:0008168 ! methyltransferase activity
+property_value: skos:exactMatch EC:2.1.1.246
+property_value: skos:exactMatch RHEA:45208
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18530" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: hjd
creation_date: 2013-05-06T15:07:20Z
@@ -596695,6 +614060,8 @@
xref: RHEA:26297
is_a: GO:0016783 ! sulfurtransferase activity
relationship: part_of GO:0009228 ! thiamine biosynthetic process
+property_value: skos:exactMatch EC:2.8.1.10
+property_value: skos:exactMatch RHEA:26297
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28942" xsd:anyURI
created_by: pr
creation_date: 2013-05-28T12:36:04Z
@@ -596982,6 +614349,9 @@
xref: EC:1.13.11.58
xref: RHEA:30291
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
+property_value: skos:exactMatch EC:1.13.11.58
+property_value: skos:exactMatch RHEA:30291
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: pr
creation_date: 2013-07-03T12:20:57Z
@@ -596993,8 +614363,12 @@
synonym: "peroxygenase activity" BROAD [PMID:19467604]
synonym: "plant seed peroxidase activity" RELATED []
xref: EC:1.11.2.3
+xref: MetaCyc:RXN-1064
xref: MetaCyc:RXN-11819
is_a: GO:0016684 ! oxidoreductase activity, acting on peroxide as acceptor
+property_value: skos:exactMatch EC:1.11.2.3
+property_value: skos:exactMatch MetaCyc:RXN-11819
+property_value: skos:narrowMatch MetaCyc:RXN-1064
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI
created_by: tb
@@ -597251,6 +614625,7 @@
synonym: "histone H3K14 deacetylase activity" BROAD []
is_a: GO:0141050 ! histone H3K deacetylase activity
is_a: GO:0141221 ! histone deacetylase activity, hydrolytic mechanism
+property_value: skos:broadMatch EC:3.5.1.98
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: pr
@@ -597375,8 +614750,6 @@
namespace: molecular_function
def: "Catalysis of the removal of the cap from an unmethylated 5'-end capped RNA resulting in the release of the entire cap structure (GpppN) and a 5' monophosphorylated RNA." [GOC:dgf, PMID:20802481]
synonym: "G(5')pppN pyrophosphatase activity" RELATED []
-xref: Reactome:R-HSA-9935300 "DXO decaps NAD-capped RNA (NAD-RNA)"
-xref: Reactome:R-HSA-9935319 "DXO decaps incompletely capped RNA (GpppN-RNA)"
is_a: GO:0016891 ! RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
created_by: tb
creation_date: 2013-08-26T17:51:00Z
@@ -597553,8 +614926,11 @@
namespace: molecular_function
def: "Catalysis of the reaction: acetyl-CoA + N-terminal L-seryl-[protein] = CoA + H+ + N-terminal Nalpha-acetyl-L-seryl-[protein]." [PMID:23912279, RHEA:50504]
synonym: "peptide-serine-alpha-N-acetyltransferase activity" EXACT []
+xref: EC:2.3.1.257
xref: RHEA:50504
is_a: GO:0004596 ! protein-N-terminal amino-acid acetyltransferase activity
+property_value: skos:exactMatch RHEA:50504
+property_value: skos:narrowMatch EC:2.3.1.257
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27532" xsd:anyURI
created_by: tb
creation_date: 2013-09-11T20:13:40Z
@@ -598179,6 +615555,7 @@
synonym: "histone threonine kinase activity (H2A-T120 specific)" EXACT []
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0140995 ! histone H2A kinase activity
+property_value: skos:broadMatch EC:2.7.11.1
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30578" xsd:anyURI
created_by: sp
@@ -598349,6 +615726,7 @@
xref: RHEA:43228
is_a: GO:0036009 ! protein-glutamine N-methyltransferase activity
is_a: GO:0140940 ! histone H2A methyltransferase activity
+property_value: skos:exactMatch RHEA:43228
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24687" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29860" xsd:anyURI
@@ -599041,31 +616419,37 @@
[Term]
id: GO:1990338
-name: laminin-14 complex
+name: laminin-423 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha4, beta2 and gamma3 polypeptide chains." [GOC:bhm, GOC:dph, PMID:15979864, PMID:17453709]
+def: "A laminin complex composed of alpha4, beta2 and gamma3 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
+synonym: "laminin-14 complex" EXACT []
synonym: "laminin-423" EXACT [GOC:dph, GOC:sl, PMID:15979864]
-is_a: GO:0043256 ! laminin complex
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
created_by: bhm
creation_date: 2014-03-20T23:37:11Z
[Term]
id: GO:1990339
-name: laminin-522 complex
+name: laminin-522 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha5, beta2 and gamma2 polypeptide chains." [GOC:bhm, GOC:dph, PMID:15979864, PMID:17453709]
+def: "A laminin complex composed of alpha5, beta2 and gamma2 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
synonym: "laminin-522" EXACT []
-is_a: GO:0043256 ! laminin complex
+synonym: "laminin-522 complex" EXACT []
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
created_by: bhm
creation_date: 2014-03-20T23:41:32Z
[Term]
id: GO:1990340
-name: laminin-15 complex
+name: laminin-523 trimer
namespace: cellular_component
-def: "A laminin complex composed of alpha5, beta2 and gamma3 polypeptide chains." [GOC:bhm, PMID:17453709]
+def: "A laminin complex composed of alpha5, beta2 and gamma3 polypeptide chains." [PMID:15979864, PMID:21421915, PMID:23263632]
+synonym: "laminin-15 complex" EXACT []
synonym: "laminin-523" EXACT []
-is_a: GO:0043256 ! laminin complex
+is_a: GO:0043256 ! laminin trimer
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30807" xsd:anyURI
created_by: bhm
creation_date: 2014-03-20T23:48:25Z
@@ -599073,9 +616457,10 @@
id: GO:1990341
name: thrombospondin complex
namespace: cellular_component
-def: "A homotrimeric or homopentameric glycoprotein that functions at the interface of the cell membrane and the extracellular matrix through its interactions with proteins and proteoglycans, such as collagens, integrins and fibronectin, to regulate matrix structure and cellular behaviour." [GOC:bhm, PMID:18193164]
+def: "A homotrimeric or homopentameric glycoprotein that functions at the interface of the cell membrane and the extracellular matrix through its interactions with proteins and proteoglycans, such as collagens, integrins and fibronectin, to regulate matrix structure and cellular behaviour." [GOC:bhm, PMID:15094109, PMID:18193164]
is_a: GO:0032991 ! protein-containing complex
-relationship: part_of GO:0031012 ! extracellular matrix
+relationship: part_of GO:0140149 ! non-collagenous component of interstitial matrix
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31065" xsd:anyURI
created_by: bhm
creation_date: 2014-03-21T14:27:07Z
@@ -599292,7 +616677,9 @@
synonym: "butanol dehydrogenase activity" BROAD []
xref: RHEA:33199
is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity
+property_value: skos:exactMatch RHEA:33199
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27136" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: tt
creation_date: 2014-04-23T21:14:09Z
@@ -599808,6 +617195,8 @@
xref: RHEA:42688
is_a: GO:0016846 ! carbon-sulfur lyase activity
relationship: part_of GO:0052699 ! ergothioneine biosynthetic process
+property_value: skos:exactMatch RHEA:42688
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: mah
creation_date: 2014-07-02T15:45:43Z
@@ -599929,6 +617318,9 @@
xref: EC:2.7.14.1
xref: RHEA:43384
is_a: GO:0004672 ! protein kinase activity
+property_value: skos:exactMatch EC:2.7.14.1
+property_value: skos:exactMatch RHEA:43384
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2014-07-23T13:35:56Z
@@ -600099,6 +617491,7 @@
def: "Catalysis of the reaction: MAP kinase threonine phosphate + H2O = MAP kinase threonine + phosphate and MAP kinase serine phosphate + H2O = MAP kinase serine + phosphate." [PMID:10398679]
is_a: GO:0004722 ! protein serine/threonine phosphatase activity
is_a: GO:0033549 ! MAP kinase phosphatase activity
+property_value: skos:broadMatch EC:3.1.3.16
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: al
creation_date: 2014-07-31T12:21:04Z
@@ -600270,12 +617663,13 @@
[Term]
id: GO:1990453
-name: nucleosome disassembly/reassembly complex
+name: TINTIN complex
namespace: cellular_component
-def: "A protein complex involved in the disassembly and subsequent reassembly of nucleosomes. It associates with the coding region of transcriptionally active genes where it interacts with the RNA polymerase II and affects its processivity during co-transcriptional RNA processing and maturation. It exists as a functionally independent part of the NuA4 complex." [GOC:bhm, PMID:24843044]
-comment: An example of this is EAF7 in Saccharomyces cerevisiae (P53911) in PMID:24843044 (inferred from direct assay).
-synonym: "eaf5/7/3 complex" NARROW []
+def: "A protein complex involved in the disassembly and subsequent reassembly of nucleosomes. It associates with the coding region of transcriptionally active genes where it interacts with the RNA polymerase II and affects its processivity during co-transcriptional RNA processing and maturation. It exists as a functionally independent part of the NuA4 complex." [GOC:bhm, PMID:24843044, PMID:36190236]
+synonym: "eaf5/7/3 complex" EXACT []
+synonym: "nucleosome disassembly/reassembly complex" BROAD []
is_a: GO:0140513 ! nuclear protein-containing complex
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31211" xsd:anyURI
created_by: bhm
creation_date: 2014-08-08T15:18:30Z
@@ -600408,6 +617802,9 @@
xref: RHEA:11272
is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
is_a: GO:0033719 ! (2R)-oxo-acid reductase activity
+property_value: skos:exactMatch EC:1.1.5.10
+property_value: skos:exactMatch MetaCyc:RXN-14931
+property_value: skos:exactMatch RHEA:11272
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
created_by: pr
creation_date: 2014-08-22T10:13:42Z
@@ -600988,6 +618385,7 @@
def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of the DNA helix in the direction 3' to 5'." [PMID:25165823]
is_a: GO:0017116 ! single-stranded DNA helicase activity
is_a: GO:0043138 ! 3'-5' DNA helicase activity
+property_value: skos:broadMatch EC:3.6.4.12
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: al
creation_date: 2014-10-22T10:17:40Z
@@ -601163,6 +618561,8 @@
def: "Catalysis of the reaction: S-methyl-5'-thioadenosine + thermospermine + H+ = S-adenosyl 3-(methylthio)propylamine + spermidine." [PMID:24906355, RHEA:57836]
xref: RHEA:57836
is_a: GO:0046592 ! polyamine oxidase activity
+property_value: skos:exactMatch RHEA:57836
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: tb
creation_date: 2014-11-13T00:41:59Z
@@ -601676,7 +619076,7 @@
namespace: molecular_function
def: "Binds to and increases the activity of the enzyme phospholipase D." [PMID:7972129]
is_a: GO:0016004 ! phospholipase activator activity
-relationship: positively_regulates GO:0004630 ! phospholipase D activity
+relationship: positively_regulates GO:0004630 ! D-type glycerophospholipase activity
created_by: sl
creation_date: 2014-12-10T21:04:46Z
@@ -601700,6 +619100,9 @@
xref: MetaCyc:RXN-15011
xref: RHEA:49472
is_a: GO:0016763 ! pentosyltransferase activity
+property_value: skos:exactMatch EC:2.4.2.58
+property_value: skos:exactMatch MetaCyc:RXN-15011
+property_value: skos:exactMatch RHEA:49472
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28324" xsd:anyURI
created_by: tb
creation_date: 2014-12-12T18:22:20Z
@@ -601795,6 +619198,8 @@
synonym: "L-talarate dehydratase activity" EXACT []
xref: RHEA:44028
is_a: GO:0016836 ! hydro-lyase activity
+property_value: skos:exactMatch RHEA:44028
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: jl
creation_date: 2014-12-16T14:23:55Z
@@ -601836,7 +619241,9 @@
name: 3' overhang single-stranded DNA endodeoxyribonuclease activity
namespace: molecular_function
def: "Catalysis of the hydrolysis of ester linkages within 3' overhang single-stranded deoxyribonucleic acid by creating internal breaks." [PMID:25203555]
+xref: EC:3.1.31.1
is_a: GO:0000014 ! single-stranded DNA endodeoxyribonuclease activity
+property_value: skos:narrowMatch EC:3.1.31.1
created_by: al
creation_date: 2015-01-06T15:21:28Z
@@ -601908,6 +619315,7 @@
namespace: molecular_function
def: "Generation of a 'twisting' activity resulting in the scission of a membrane, driven by GTP hydrolysis." [PMID:11242086, PMID:23530241, PMID:24515348]
is_a: GO:0061791 ! GTPase motor activity
+property_value: skos:broadMatch RHEA:19669
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28520" xsd:anyURI
created_by: vw
creation_date: 2015-01-19T14:26:50Z
@@ -602531,6 +619939,9 @@
xref: EC:1.3.98.1
xref: RHEA:30059
is_a: GO:0004152 ! dihydroorotate dehydrogenase activity
+property_value: skos:exactMatch EC:1.3.98.1
+property_value: skos:exactMatch RHEA:30059
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: al
creation_date: 2015-02-26T15:47:30Z
@@ -602932,7 +620343,11 @@
namespace: molecular_function
def: "Catalysis of the transfer of a palmitoleoyl group, a 16-carbon monounsaturated fatty acid (C16:1), to an acceptor molecule." [PMID:17141155, PMID:25731175]
comment: Note that this term should not be confused with 'palmitoyltransferase activity ; GO:0016409'.
+xref: EC:2.3.1.250
+xref: RHEA:45336
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
+property_value: skos:narrowMatch EC:2.3.1.250
+property_value: skos:narrowMatch RHEA:45336
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27365" xsd:anyURI
created_by: sp
creation_date: 2015-03-13T08:58:25Z
@@ -602942,7 +620357,11 @@
name: palmitoleyl hydrolase activity
namespace: molecular_function
def: "Catalysis of a hydrolase reaction that removes a palmitoleyl moiety, a 16-carbon monounsaturated fatty acid (C16:1), from some substrate." [PMID:25731175]
+xref: EC:3.1.1.98
+xref: RHEA:45340
is_a: GO:0052689 ! carboxylic ester hydrolase activity
+property_value: skos:narrowMatch EC:3.1.1.98
+property_value: skos:narrowMatch RHEA:45340
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24890" xsd:anyURI
created_by: sp
creation_date: 2015-03-13T09:00:05Z
@@ -603089,11 +620508,12 @@
id: GO:1990713
name: survivin complex
namespace: cellular_component
-def: "A protein complex that negatively regulates apoptotic processes. In human, this anti-apoptotic complex is a homodimer of BIRC5 (survivin) and provides one survivin molecule to the chromosomal passenger complex (CPC)." [GOC:bhm, PMID:10949038]
+def: "A protein complex that negatively regulates apoptotic processes. Complex contains a component which belongs to the family of baculoviral IAP (inhibitor of apoptosis) repeat-containing proteins." [GOC:bhm, PMID:10929712, PMID:10949038, PMID:16282325, PMID:19153467]
comment: An example of this is BIRC5 in human (UniProt symbol O15392) in PMID:10949038 (inferred from physical interaction).
synonym: "Baculoviral IAP repeat-containing protein 5 complex" EXACT []
synonym: "survivin homodimer complex" NARROW []
is_a: GO:0140513 ! nuclear protein-containing complex
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30914" xsd:anyURI
created_by: bhm
creation_date: 2015-03-26T14:21:46Z
@@ -603369,6 +620789,9 @@
xref: EC:3.1.3.96
xref: RHEA:10944
is_a: GO:0016791 ! phosphatase activity
+property_value: skos:exactMatch EC:3.1.3.96
+property_value: skos:exactMatch RHEA:10944
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: vw
creation_date: 2015-05-02T11:05:50Z
@@ -603834,13 +621257,13 @@
[Term]
id: GO:1990787
-name: negative regulation of hh target transcription factor activity
+name: obsolete negative regulation of hh target transcription factor activity
namespace: biological_process
-def: "Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling." [GOC:bhm, PMID:24311597]
-subset: gocheck_obsoletion_candidate
+def: "OBSOLETE. Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling." [GOC:bhm, PMID:24311597]
+comment: The reason for obsoletion is that this term represents a molecular function.
synonym: "negative regulation of hedgehog target transcription factor" EXACT []
-is_a: GO:0045879 ! negative regulation of smoothened signaling pathway
-is_a: GO:0051090 ! regulation of DNA-binding transcription factor activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30856" xsd:anyURI
+is_obsolete: true
created_by: bhm
creation_date: 2015-06-26T09:54:29Z
@@ -604186,10 +621609,12 @@
xref: MetaCyc:POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN
xref: Reactome:R-HSA-72185 "mRNA polyadenylation"
xref: Reactome:R-HSA-9833031 "Polyadenylation of respiratory syncytial virus subgenomic positive-sense mRNAs"
-xref: Reactome:R-HSA-9936998 "MTPAP polyadenylates mitochondrial mRNA"
xref: RHEA:11332
is_a: GO:0070566 ! adenylyltransferase activity
+property_value: skos:exactMatch EC:2.7.7.19
+property_value: skos:exactMatch RHEA:11332
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24859" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI
created_by: vw
creation_date: 2015-07-31T09:38:31Z
@@ -604399,6 +621824,7 @@
def: "Catalysis of the reaction: a 3'-end uridylyl-uridine-RNA = a 3'-end 2',3'-cyclophospho-uridine-RNA + uridine." [PMID:23022480, RHEA:46052]
xref: RHEA:46052
is_a: GO:0000175 ! 3'-5'-RNA exonuclease activity
+property_value: skos:exactMatch RHEA:46052
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30714" xsd:anyURI
created_by: al
creation_date: 2015-08-26T10:24:51Z
@@ -604474,7 +621900,8 @@
namespace: biological_process
def: "The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature." [PMID:17260010, PMID:20363363]
xref: Reactome:R-HSA-166187 "Mitochondrial Uncoupling"
-is_a: GO:0008152 ! metabolic process
+is_a: GO:0001659 ! temperature homeostasis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31122" xsd:anyURI
created_by: sl
creation_date: 2015-08-31T18:19:49Z
@@ -604922,6 +622349,7 @@
def: "Catalysis of the reaction: a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in 18S rRNA + ADP + phosphate + CoA + H+." [PMID:25402480, RHEA:51424]
xref: RHEA:51424
is_a: GO:0008080 ! N-acetyltransferase activity
+property_value: skos:exactMatch RHEA:51424
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29506" xsd:anyURI
created_by: al
creation_date: 2015-10-28T13:27:35Z
@@ -605392,8 +622820,15 @@
id: GO:1990929
name: sulfoquinovosidase activity
namespace: molecular_function
-def: "Catalyzes the hydrolysis of terminal non-reducing alpha-sulfoquinovoside residues in alpha-sulfoquinovosyl diacylglycerides and alpha-sulfoquinovosyl glycerol, generating alpha-sulfoquinovose." [GOC:imk, PMID:26878550]
-is_a: GO:0016798 ! hydrolase activity, acting on glycosyl bonds
+def: "Catalysis of the reaction: a 6-sulfo-alpha-D-quinovosyldiacylglycerol + H2O = 6-sulfo-alpha-D-quinovose + a 1,2-diacyl-sn-glycerol." [PMID:26878550, RHEA:49452]
+xref: EC:3.2.1.199
+xref: MetaCyc:RXN-17700
+xref: RHEA:49452
+is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds
+property_value: skos:exactMatch EC:3.2.1.199
+property_value: skos:exactMatch MetaCyc:RXN-17700
+property_value: skos:exactMatch RHEA:49452
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30910" xsd:anyURI
created_by: tb
creation_date: 2016-02-19T01:18:37Z
@@ -605407,6 +622842,8 @@
xref: EC:1.14.11.54
xref: RHEA:49516
is_a: GO:0035515 ! oxidative RNA demethylase activity
+property_value: skos:exactMatch EC:1.14.11.54
+property_value: skos:exactMatch RHEA:49516
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21812" xsd:anyURI
created_by: sp
creation_date: 2016-03-10T08:06:47Z
@@ -605422,6 +622859,8 @@
xref: EC:1.14.11.53
xref: RHEA:49520
is_a: GO:0035515 ! oxidative RNA demethylase activity
+property_value: skos:exactMatch EC:1.14.11.53
+property_value: skos:exactMatch RHEA:49520
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21812" xsd:anyURI
created_by: sp
creation_date: 2016-03-10T08:10:10Z
@@ -605819,14 +623258,14 @@
id: GO:1990971
name: EMILIN complex
namespace: cellular_component
-def: "Glycoprotein complex of the C1q/TNF superfamily found in the extracellular matrix (ECM) where it is an important component of the elastic fiber system. A homotrimer that will combine to form supramolecular EMILIN structures." [GOC:bhm, PMID:10821830]
-comment: An example of this is EMILIN-1 in human (Q9Y6C2) in PMID:10821830 (inferred from direct assay).
+def: "The elastin microfibril interface located protein (EMILINs) are glycoprotein complexes of the C1q/TNF superfamily characterized by an N-terminal EMI domain. EMILIN homotrimers assemble to form supramolecular EMILIN structures." [PMID:10821830]
synonym: "Elastic microfibrillar interface 1 complex" NARROW []
synonym: "Elastic microfibrillar interface 2 complex" NARROW []
synonym: "EMILIN-1 complex" NARROW []
synonym: "EMILIN-2 complex" NARROW []
is_a: GO:0098637 ! protein complex involved in cell-matrix adhesion
-relationship: part_of GO:0031012 ! extracellular matrix
+relationship: part_of GO:0071953 ! elastic fiber
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31133" xsd:anyURI
created_by: bhm
creation_date: 2016-06-21T14:41:18Z
@@ -605834,8 +623273,7 @@
id: GO:1990972
name: multimerin complex
namespace: cellular_component
-def: "Glycoprotein complex of the C1q/TNF superfamily involved in cell adhesion. A homotrimer that will combine to form supramolecular Multimerin structures." [GOC:bhm, PMID:9454761]
-comment: An example of this is Multimerin-1 in human (Q13201) in PMID:9454761.
+def: "Glycoprotein complex of the C1q/TNF superfamily involved in cell adhesion. A homotrimer that will combine to form supramolecular Multimerin structures." [PMID:18297547, PMID:22566882, PMID:9454761]
synonym: "Elastic microfibrillar interface 3 complex" NARROW []
synonym: "Elastic microfibrillar interface 4 complex" NARROW []
synonym: "EMILIN-3 complex" NARROW []
@@ -605845,7 +623283,8 @@
synonym: "p155 complex" NARROW []
synonym: "Platelet glycoprotein Ia* complex" NARROW []
is_a: GO:0098637 ! protein complex involved in cell-matrix adhesion
-relationship: part_of GO:0031012 ! extracellular matrix
+relationship: part_of GO:0071953 ! elastic fiber
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31134" xsd:anyURI
created_by: bhm
creation_date: 2016-06-21T14:49:42Z
@@ -606785,8 +624224,7 @@
synonym: "regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism" EXACT [GOC:obol]
synonym: "regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process" EXACT [GOC:obol]
synonym: "regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism" EXACT [GOC:obol]
-is_a: GO:0009894 ! regulation of catabolic process
-is_a: GO:1903050 ! regulation of proteolysis involved in protein catabolic process
+is_a: GO:0042176 ! regulation of protein catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006511 ! ubiquitin-dependent protein catabolic process
relationship: regulates GO:0006511 ! ubiquitin-dependent protein catabolic process
@@ -606808,8 +624246,7 @@
synonym: "negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism" NARROW [GOC:obol]
synonym: "negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process" NARROW [GOC:obol]
synonym: "negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism" NARROW [GOC:obol]
-is_a: GO:0009895 ! negative regulation of catabolic process
-is_a: GO:1903051 ! negative regulation of proteolysis involved in protein catabolic process
+is_a: GO:0042177 ! negative regulation of protein catabolic process
is_a: GO:2000058 ! regulation of ubiquitin-dependent protein catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006511 ! ubiquitin-dependent protein catabolic process
@@ -606831,8 +624268,7 @@
synonym: "positive regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism" NARROW [GOC:obol]
synonym: "positive regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process" NARROW [GOC:obol]
synonym: "positive regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism" NARROW [GOC:obol]
-is_a: GO:0009896 ! positive regulation of catabolic process
-is_a: GO:1903052 ! positive regulation of proteolysis involved in protein catabolic process
+is_a: GO:0045732 ! positive regulation of protein catabolic process
is_a: GO:2000058 ! regulation of ubiquitin-dependent protein catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006511 ! ubiquitin-dependent protein catabolic process
@@ -607199,42 +624635,43 @@
[Term]
id: GO:2000084
-name: regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
+name: obsolete regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol]
-is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
-relationship: regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060231
+consider: GO:0061206
created_by: dph
creation_date: 2010-09-03T06:06:41Z
[Term]
id: GO:2000085
-name: negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
+name: obsolete negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
namespace: biological_process
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10]
+def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "negative regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol]
-is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
-is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
-relationship: negatively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060231
+consider: GO:0061206
created_by: dph
creation_date: 2010-09-03T06:08:21Z
[Term]
id: GO:2000086
-name: positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
+name: obsolete positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol]
-is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
-is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
-relationship: positively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0060231
+consider: GO:0061206
created_by: dph
creation_date: 2010-09-03T06:08:24Z
@@ -607964,44 +625401,43 @@
[Term]
id: GO:2000139
-name: regulation of octopamine signaling pathway involved in response to food
+name: obsolete regulation of octopamine signaling pathway involved in response to food
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food." [GOC:mah, PMID:19609300]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food." [GOC:mah, PMID:19609300]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "regulation of octopamine signalling pathway involved in response to food" EXACT [GOC:mah]
-is_a: GO:2000128 ! regulation of octopamine signaling pathway
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0071935 ! octopamine signaling pathway involved in response to food
-relationship: regulates GO:0071935 ! octopamine signaling pathway involved in response to food
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0032094
+consider: GO:2000128
created_by: mah
creation_date: 2010-09-30T02:48:07Z
[Term]
id: GO:2000140
-name: negative regulation of octopamine signaling pathway involved in response to food
+name: obsolete negative regulation of octopamine signaling pathway involved in response to food
namespace: biological_process
-def: "Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway involved in response to food." [GOC:mah, PMID:19609300]
+def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway involved in response to food." [GOC:mah, PMID:19609300]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "negative regulation of octopamine signalling pathway involved in response to food" EXACT [GOC:mah]
-is_a: GO:0032096 ! negative regulation of response to food
-is_a: GO:2000129 ! negative regulation of octopamine signaling pathway
-is_a: GO:2000139 ! regulation of octopamine signaling pathway involved in response to food
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0071935 ! octopamine signaling pathway involved in response to food
-relationship: negatively_regulates GO:0071935 ! octopamine signaling pathway involved in response to food
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0032094
+consider: GO:2000129
created_by: mah
creation_date: 2010-09-30T02:48:10Z
[Term]
id: GO:2000141
-name: positive regulation of octopamine signaling pathway involved in response to food
+name: obsolete positive regulation of octopamine signaling pathway involved in response to food
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food." [GOC:mah, PMID:19609300]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food." [GOC:mah, PMID:19609300]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive regulation of octopamine signalling pathway involved in response to food" EXACT [GOC:mah]
-is_a: GO:0032097 ! positive regulation of response to food
-is_a: GO:2000130 ! positive regulation of octopamine signaling pathway
-is_a: GO:2000139 ! regulation of octopamine signaling pathway involved in response to food
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0071935 ! octopamine signaling pathway involved in response to food
-relationship: positively_regulates GO:0071935 ! octopamine signaling pathway involved in response to food
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0032094
+consider: GO:2000130
created_by: mah
creation_date: 2010-09-30T02:48:12Z
@@ -609063,8 +626499,8 @@
is_a: GO:0006521 ! regulation of amino acid metabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0006560 ! proline metabolic process
-relationship: regulates GO:0006560 ! proline metabolic process
+intersection_of: regulates GO:0006560 ! L-proline metabolic process
+relationship: regulates GO:0006560 ! L-proline metabolic process
created_by: mah
creation_date: 2010-11-03T02:45:20Z
@@ -609235,9 +626671,9 @@
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah]
synonym: "negative regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol]
-is_a: GO:0030857 ! negative regulation of epithelial cell differentiation
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:2000226 ! regulation of pancreatic A cell differentiation
+is_a: GO:7770019 ! negative regulation of enteroendocrine cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003310 ! pancreatic A cell differentiation
relationship: negatively_regulates GO:0003310 ! pancreatic A cell differentiation
@@ -610276,32 +627712,31 @@
[Term]
id: GO:2000298
-name: regulation of Rho-dependent protein serine/threonine kinase activity
+name: obsolete regulation of Rho-dependent protein serine/threonine kinase activity
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity." [GOC:mah]
-subset: gocheck_obsoletion_candidate
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity." [GOC:mah]
+comment: This term was obsoelted because it represents a molecular function.
synonym: "regulation of Rho-associated protein kinase activity" EXACT [GOC:obol]
synonym: "regulation of ROCK kinase activity" EXACT [GOC:obol]
-is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0072518 ! Rho-dependent protein serine/threonine kinase activity
-relationship: regulates GO:0072518 ! Rho-dependent protein serine/threonine kinase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21233" xsd:anyURI
+is_obsolete: true
+consider: GO:0030695
+consider: GO:0035023
created_by: mah
creation_date: 2010-12-23T11:44:50Z
[Term]
id: GO:2000299
-name: negative regulation of Rho-dependent protein serine/threonine kinase activity
+name: obsolete negative regulation of Rho-dependent protein serine/threonine kinase activity
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity." [GOC:mah]
-subset: gocheck_obsoletion_candidate
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity." [GOC:mah]
+comment: This term was obsoleted because it represents a molecular function.
synonym: "negative regulation of Rho-associated protein kinase activity" EXACT [GOC:obol]
synonym: "negative regulation of ROCK kinase activity" EXACT [GOC:obol]
-is_a: GO:0071901 ! negative regulation of protein serine/threonine kinase activity
-is_a: GO:2000298 ! regulation of Rho-dependent protein serine/threonine kinase activity
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0072518 ! Rho-dependent protein serine/threonine kinase activity
-relationship: negatively_regulates GO:0072518 ! Rho-dependent protein serine/threonine kinase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21233" xsd:anyURI
+is_obsolete: true
+consider: GO:0030291
+consider: GO:0035024
created_by: mah
creation_date: 2010-12-23T11:44:57Z
@@ -610355,7 +627790,6 @@
synonym: "regulation of ceramide biosynthesis" EXACT [GOC:obol]
synonym: "regulation of ceramide formation" EXACT [GOC:obol]
synonym: "regulation of ceramide synthesis" EXACT [GOC:obol]
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0090153 ! regulation of sphingolipid biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0046513 ! ceramide biosynthetic process
@@ -610373,7 +627807,6 @@
synonym: "positive regulation of ceramide formation" EXACT [GOC:obol]
synonym: "positive regulation of ceramide synthesis" EXACT [GOC:obol]
xref: Reactome:R-HSA-5626978 "TNFR1-mediated ceramide production"
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0090154 ! positive regulation of sphingolipid biosynthetic process
is_a: GO:2000303 ! regulation of ceramide biosynthetic process
intersection_of: GO:0065007 ! biological regulation
@@ -610384,17 +627817,18 @@
[Term]
id: GO:2000305
-name: semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance
+name: obsolete semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance
namespace: biological_process
-def: "Any semaphorin-plexin signaling pathway that is involved in regulation of photoreceptor cell axon guidance." [GOC:obol]
+def: "OBSOLETE. Any semaphorin-plexin signaling pathway that is involved in regulation of photoreceptor cell axon guidance." [GOC:obol]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "semaphorin-plexin signaling pathway of regulation of photoreceptor cell axon guidance" EXACT [GOC:obol]
synonym: "semaphorin-plexin signaling pathway of regulation of photoreceptor cell axon pathfinding" EXACT [GOC:obol]
synonym: "semaphorin-plexin signalling pathway of regulation of photoreceptor cell axon guidance" EXACT [GOC:obol]
synonym: "semaphorin-plexin signalling pathway of regulation of photoreceptor cell axon pathfinding" EXACT [GOC:obol]
-is_a: GO:0071526 ! semaphorin-plexin signaling pathway
-intersection_of: GO:0071526 ! semaphorin-plexin signaling pathway
-intersection_of: part_of GO:2000289 ! regulation of photoreceptor cell axon guidance
-relationship: part_of GO:2000289 ! regulation of photoreceptor cell axon guidance
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0071526
+consider: GO:2000289
created_by: sart
creation_date: 2011-01-07T01:42:34Z
@@ -610501,45 +627935,43 @@
[Term]
id: GO:2000313
-name: regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
+name: obsolete regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation." [GOC:BHF]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation." [GOC:BHF]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:obol]
-is_a: GO:0040036 ! regulation of fibroblast growth factor receptor signaling pathway
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0060825 ! fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
-relationship: regulates GO:0060825 ! fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0021999
+consider: GO:0040036
created_by: vk
creation_date: 2011-01-18T10:26:22Z
[Term]
id: GO:2000314
-name: negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
+name: obsolete negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation." [GOC:BHF]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation." [GOC:BHF]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "negative regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:obol]
-is_a: GO:0040037 ! negative regulation of fibroblast growth factor receptor signaling pathway
-is_a: GO:0051093 ! negative regulation of developmental process
-is_a: GO:2000313 ! regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0060825 ! fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
-relationship: negatively_regulates GO:0060825 ! fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0021999
+consider: GO:0040036
created_by: vk
creation_date: 2011-01-18T10:26:56Z
[Term]
id: GO:2000315
-name: positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
+name: obsolete positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation." [GOC:BHF]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation." [GOC:BHF]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:obol]
-is_a: GO:0045743 ! positive regulation of fibroblast growth factor receptor signaling pathway
-is_a: GO:0051094 ! positive regulation of developmental process
-is_a: GO:0051240 ! positive regulation of multicellular organismal process
-is_a: GO:2000313 ! regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0060825 ! fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
-relationship: positively_regulates GO:0060825 ! fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0021999
+consider: GO:0045743
created_by: vk
creation_date: 2011-01-18T10:27:19Z
@@ -613162,14 +630594,14 @@
[Term]
id: GO:2000496
-name: negative regulation of cell proliferation involved in compound eye morphogenesis
+name: obsolete negative regulation of cell proliferation involved in compound eye morphogenesis
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol]
-is_a: GO:0008285 ! negative regulation of cell population proliferation
-is_a: GO:2000495 ! regulation of cell proliferation involved in compound eye morphogenesis
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis
-relationship: negatively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0001745
+consider: GO:0008285
created_by: bf
creation_date: 2011-03-18T02:19:22Z
@@ -613529,15 +630961,14 @@
[Term]
id: GO:2000526
-name: positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
+name: obsolete positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
namespace: biological_process
-def: "Any positive regulation of glycoprotein biosynthetic process that is involved in immunological synapse formation." [GOC:obol]
+def: "OBSOLETE. Any positive regulation of glycoprotein biosynthetic process that is involved in immunological synapse formation." [GOC:obol]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM.
synonym: "positive regulation of glycoprotein biosynthetic process of formation of immunological synapse" EXACT [GOC:obol]
synonym: "positive regulation of glycoprotein biosynthetic process of immunological synapse formation" EXACT [GOC:obol]
-is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process
-intersection_of: GO:0010560 ! positive regulation of glycoprotein biosynthetic process
-intersection_of: part_of GO:0001771 ! immunological synapse formation
-relationship: part_of GO:0001771 ! immunological synapse formation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31228" xsd:anyURI
+is_obsolete: true
created_by: ebc
creation_date: 2011-03-23T10:42:30Z
@@ -615940,54 +633371,55 @@
[Term]
id: GO:2000702
-name: regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
+name: obsolete regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "regulation of FGF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "regulation of FGF receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "regulation of FGFR signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol]
-is_a: GO:0040036 ! regulation of fibroblast growth factor receptor signaling pathway
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:2000699 ! fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
-relationship: regulates GO:2000699 ! fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0040036
+consider: GO:0060676
created_by: yaf
creation_date: 2011-05-25T09:48:15Z
[Term]
id: GO:2000703
-name: negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
+name: obsolete negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "negative regulation of FGF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "negative regulation of FGF receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "negative regulation of FGFR signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "negative regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "negative regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol]
-is_a: GO:0040037 ! negative regulation of fibroblast growth factor receptor signaling pathway
-is_a: GO:2000702 ! regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:2000699 ! fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
-relationship: negatively_regulates GO:2000699 ! fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0040037
+consider: GO:0060676
created_by: yaf
creation_date: 2011-05-25T09:48:22Z
[Term]
id: GO:2000704
-name: positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
+name: obsolete positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive regulation of FGF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "positive regulation of FGF receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "positive regulation of FGFR signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "positive regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "positive regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol]
-is_a: GO:0045743 ! positive regulation of fibroblast growth factor receptor signaling pathway
-is_a: GO:2000702 ! regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:2000699 ! fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
-relationship: positively_regulates GO:2000699 ! fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0045743
+consider: GO:0060676
created_by: yaf
creation_date: 2011-05-25T09:48:27Z
@@ -616418,54 +633850,49 @@
[Term]
id: GO:2000733
-name: regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
+name: obsolete regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation." [GOC:obol]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation." [GOC:obol]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "regulation of GDNF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol]
-is_a: GO:0009966 ! regulation of signal transduction
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:2000701 ! glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
-relationship: regulates GO:2000701 ! glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: yaf
creation_date: 2011-06-13T11:14:40Z
[Term]
id: GO:2000734
-name: negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
+name: obsolete negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation." [GOC:obol]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation." [GOC:obol]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "negative regulation of GDNF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "negative regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "negative regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "negative regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol]
-is_a: GO:0009968 ! negative regulation of signal transduction
-is_a: GO:2000733 ! regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:2000701 ! glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
-relationship: negatively_regulates GO:2000701 ! glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: yaf
creation_date: 2011-06-13T11:14:44Z
[Term]
id: GO:2000735
-name: positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
+name: obsolete positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation." [GOC:obol]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation." [GOC:obol]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive regulation of GDNF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "positive regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "positive regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol]
synonym: "positive regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol]
-is_a: GO:0009967 ! positive regulation of signal transduction
-is_a: GO:2000733 ! regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:2000701 ! glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
-relationship: positively_regulates GO:2000701 ! glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
created_by: yaf
creation_date: 2011-06-13T11:14:46Z
@@ -616719,9 +634146,7 @@
synonym: "regulation of glucosylceramide breakdown" EXACT [GOC:obol]
synonym: "regulation of glucosylceramide catabolism" EXACT [GOC:obol]
synonym: "regulation of glucosylceramide degradation" EXACT [GOC:obol]
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0050994 ! regulation of lipid catabolic process
-is_a: GO:1905038 ! regulation of membrane lipid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006680 ! glucosylceramide catabolic process
relationship: regulates GO:0006680 ! glucosylceramide catabolic process
@@ -616736,7 +634161,6 @@
synonym: "positive regulation of glucosylceramide breakdown" EXACT [GOC:obol]
synonym: "positive regulation of glucosylceramide catabolism" EXACT [GOC:obol]
synonym: "positive regulation of glucosylceramide degradation" EXACT [GOC:obol]
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0050996 ! positive regulation of lipid catabolic process
is_a: GO:2000752 ! regulation of glucosylceramide catabolic process
intersection_of: GO:0065007 ! biological regulation
@@ -616753,9 +634177,7 @@
synonym: "regulation of sphingomyelin breakdown" EXACT [GOC:obol]
synonym: "regulation of sphingomyelin catabolism" EXACT [GOC:obol]
synonym: "regulation of sphingomyelin degradation" EXACT [GOC:obol]
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0060696 ! regulation of phospholipid catabolic process
-is_a: GO:1905038 ! regulation of membrane lipid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006685 ! sphingomyelin catabolic process
relationship: regulates GO:0006685 ! sphingomyelin catabolic process
@@ -616770,7 +634192,6 @@
synonym: "positive regulation of sphingomyelin breakdown" EXACT [GOC:obol]
synonym: "positive regulation of sphingomyelin catabolism" EXACT [GOC:obol]
synonym: "positive regulation of sphingomyelin degradation" EXACT [GOC:obol]
-is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0060697 ! positive regulation of phospholipid catabolic process
is_a: GO:2000754 ! regulation of sphingomyelin catabolic process
intersection_of: GO:0065007 ! biological regulation
@@ -616901,14 +634322,15 @@
[Term]
id: GO:2000764
-name: positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis
+name: obsolete positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis." [GOC:BHF]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis." [GOC:BHF]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive regulation of semaphorin-plexin signalling pathway involved in outflow tract morphogenesis" EXACT [GOC:obol]
-is_a: GO:2001262 ! positive regulation of semaphorin-plexin signaling pathway
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0071527 ! semaphorin-plexin signaling pathway involved in outflow tract morphogenesis
-relationship: positively_regulates GO:0071527 ! semaphorin-plexin signaling pathway involved in outflow tract morphogenesis
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003151
+consider: GO:2001262
created_by: vk
creation_date: 2011-06-18T04:26:00Z
@@ -617268,16 +634690,14 @@
[Term]
id: GO:2000792
-name: positive regulation of mesenchymal cell proliferation involved in lung development
+name: obsolete positive regulation of mesenchymal cell proliferation involved in lung development
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708]
-is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation
-is_a: GO:0051094 ! positive regulation of developmental process
-is_a: GO:0051240 ! positive regulation of multicellular organismal process
-is_a: GO:2000790 ! regulation of mesenchymal cell proliferation involved in lung development
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development
-relationship: positively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0002053
+consider: GO:0030324
created_by: pr
creation_date: 2011-06-24T01:53:56Z
@@ -617322,19 +634742,20 @@
[Term]
id: GO:2000796
-name: Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment
+name: obsolete Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment
namespace: biological_process
-def: "Any Notch signaling pathway that is involved in negative regulation of venous endothelial cell fate commitment." [PMID:11585794]
+def: "OBSOLETE. Any Notch signaling pathway that is involved in negative regulation of venous endothelial cell fate commitment." [PMID:11585794]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "N signaling pathway involved in negative regulation of venous endothelial cell fate commitment" EXACT [GOC:obol]
synonym: "Notch receptor signaling pathway involved in negative regulation of venous endothelial cell fate commitment" EXACT [GOC:obol]
synonym: "Notch receptor signalling pathway involved in negative regulation of venous endothelial cell fate commitment" EXACT [GOC:obol]
synonym: "Notch signalling pathway involved in negative regulation of venous endothelial cell fate commitment" EXACT [GOC:obol]
synonym: "Notch-receptor signaling pathway involved in negative regulation of venous endothelial cell fate commitment" EXACT [GOC:obol]
synonym: "Notch-receptor signalling pathway involved in negative regulation of venous endothelial cell fate commitment" EXACT [GOC:obol]
-is_a: GO:0007219 ! Notch signaling pathway
-intersection_of: GO:0007219 ! Notch signaling pathway
-intersection_of: part_of GO:2000788 ! negative regulation of venous endothelial cell fate commitment
-relationship: part_of GO:2000788 ! negative regulation of venous endothelial cell fate commitment
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007219
+consider: GO:2000788
created_by: bf
creation_date: 2011-06-27T09:07:42Z
@@ -617391,15 +634812,15 @@
[Term]
id: GO:2000801
-name: negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
+name: obsolete negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation." [GOC:BHF]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation." [GOC:BHF]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "negative regulation of endocardial cushion to mesenchymal transition involved in valve formation" EXACT [GOC:obol]
-is_a: GO:0140050 ! negative regulation of endocardial cushion to mesenchymal transition
-is_a: GO:2000800 ! regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0003199 ! endocardial cushion to mesenchymal transition involved in heart valve formation
-relationship: negatively_regulates GO:0003199 ! endocardial cushion to mesenchymal transition involved in heart valve formation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0003188
+consider: GO:0140050
created_by: bf
creation_date: 2011-07-01T12:31:22Z
@@ -617744,16 +635165,12 @@
[Term]
id: GO:2000825
-name: positive regulation of androgen receptor activity
+name: obsolete positive regulation of androgen receptor activity
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of androgen receptor activity." [GOC:obol]
-subset: gocheck_obsoletion_candidate
-is_a: GO:0006357 ! regulation of transcription by RNA polymerase II
-is_a: GO:0010469 ! regulation of signaling receptor activity
-is_a: GO:0051091 ! positive regulation of DNA-binding transcription factor activity
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0004879 ! nuclear receptor activity
-relationship: positively_regulates GO:0004879 ! nuclear receptor activity
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of androgen receptor activity." [GOC:obol]
+comment: The reason for obsoletion is that this term represents a molecular function.
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30856" xsd:anyURI
+is_obsolete: true
created_by: yaf
creation_date: 2011-07-15T10:56:14Z
@@ -622056,6 +639473,7 @@
def: "Any process that modulates the frequency, rate or extent of glucose catabolic process to ethanol." [GOC:obol]
synonym: "regulation of ethanol fermentation" EXACT [GOC:obol]
synonym: "regulation of glucose fermentation to ethanol" EXACT [GOC:obol]
+is_a: GO:0043465 ! regulation of fermentation
is_a: GO:0043470 ! regulation of carbohydrate catabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
@@ -622074,6 +639492,7 @@
is_a: GO:0009895 ! negative regulation of catabolic process
is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
+is_a: GO:1901003 ! negative regulation of fermentation
is_a: GO:2001154 ! regulation of glycolytic fermentation to ethanol
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0019655 ! pyruvate fermentation to ethanol
@@ -622513,57 +639932,49 @@
[Term]
id: GO:2001191
-name: regulation of gamma-delta T cell activation involved in immune response
+name: obsolete regulation of gamma-delta T cell activation involved in immune response
namespace: biological_process
-def: "Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response." [GOC:obol]
+def: "OBSOLETE. Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response." [GOC:obol]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "regulation of gamma-delta T cell activation during immune response" RELATED [GOC:obol]
synonym: "regulation of gamma-delta T lymphocyte activation during immune response" RELATED [GOC:obol]
synonym: "regulation of gamma-delta T-cell activation during immune response" RELATED [GOC:obol]
synonym: "regulation of gamma-delta T-lymphocyte activation during immune response" RELATED [GOC:obol]
-is_a: GO:0002697 ! regulation of immune effector process
-is_a: GO:0046643 ! regulation of gamma-delta T cell activation
-is_a: GO:0050776 ! regulation of immune response
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0002290 ! gamma-delta T cell activation involved in immune response
-relationship: regulates GO:0002290 ! gamma-delta T cell activation involved in immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0046644
created_by: yaf
creation_date: 2011-11-03T04:28:38Z
[Term]
id: GO:2001192
-name: negative regulation of gamma-delta T cell activation involved in immune response
+name: obsolete negative regulation of gamma-delta T cell activation involved in immune response
namespace: biological_process
-def: "Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell activation involved in immune response." [GOC:obol]
+def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell activation involved in immune response." [GOC:obol]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "negative regulation of gamma-delta T cell activation during immune response" RELATED [GOC:obol]
synonym: "negative regulation of gamma-delta T lymphocyte activation during immune response" RELATED [GOC:obol]
synonym: "negative regulation of gamma-delta T-cell activation during immune response" RELATED [GOC:obol]
synonym: "negative regulation of gamma-delta T-lymphocyte activation during immune response" RELATED [GOC:obol]
-is_a: GO:0002698 ! negative regulation of immune effector process
-is_a: GO:0046644 ! negative regulation of gamma-delta T cell activation
-is_a: GO:0050777 ! negative regulation of immune response
-is_a: GO:2001191 ! regulation of gamma-delta T cell activation involved in immune response
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0002290 ! gamma-delta T cell activation involved in immune response
-relationship: negatively_regulates GO:0002290 ! gamma-delta T cell activation involved in immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0046644
created_by: yaf
creation_date: 2011-11-03T04:28:44Z
[Term]
id: GO:2001193
-name: positive regulation of gamma-delta T cell activation involved in immune response
+name: obsolete positive regulation of gamma-delta T cell activation involved in immune response
namespace: biological_process
-def: "Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation involved in immune response." [GOC:obol]
+def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation involved in immune response." [GOC:obol]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "positive regulation of gamma-delta T cell activation during immune response" RELATED [GOC:obol]
synonym: "positive regulation of gamma-delta T lymphocyte activation during immune response" RELATED [GOC:obol]
synonym: "positive regulation of gamma-delta T-cell activation during immune response" RELATED [GOC:obol]
synonym: "positive regulation of gamma-delta T-lymphocyte activation during immune response" RELATED [GOC:obol]
-is_a: GO:0002699 ! positive regulation of immune effector process
-is_a: GO:0046645 ! positive regulation of gamma-delta T cell activation
-is_a: GO:0050778 ! positive regulation of immune response
-is_a: GO:2001191 ! regulation of gamma-delta T cell activation involved in immune response
-intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0002290 ! gamma-delta T cell activation involved in immune response
-relationship: positively_regulates GO:0002290 ! gamma-delta T cell activation involved in immune response
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0046645
created_by: yaf
creation_date: 2011-11-03T04:28:48Z
@@ -622576,8 +639987,8 @@
synonym: "regulation of lysine biosynthetic process via aminoadipic acid and saccharopine" EXACT [GOC:obol]
is_a: GO:1902986 ! regulation of lysine biosynthetic process via aminoadipic acid
intersection_of: GO:0065007 ! biological regulation
-intersection_of: regulates GO:0051975 ! lysine biosynthetic process via alpha-aminoadipate and saccharopine
-relationship: regulates GO:0051975 ! lysine biosynthetic process via alpha-aminoadipate and saccharopine
+intersection_of: regulates GO:0051975 ! L-lysine biosynthetic process via alpha-aminoadipate and saccharopine
+relationship: regulates GO:0051975 ! L-lysine biosynthetic process via alpha-aminoadipate and saccharopine
created_by: mcc
creation_date: 2011-11-03T07:57:11Z
@@ -622591,8 +640002,8 @@
is_a: GO:1902987 ! negative regulation of lysine biosynthetic process via aminoadipic acid
is_a: GO:2001194 ! regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine
intersection_of: GO:0065007 ! biological regulation
-intersection_of: negatively_regulates GO:0051975 ! lysine biosynthetic process via alpha-aminoadipate and saccharopine
-relationship: negatively_regulates GO:0051975 ! lysine biosynthetic process via alpha-aminoadipate and saccharopine
+intersection_of: negatively_regulates GO:0051975 ! L-lysine biosynthetic process via alpha-aminoadipate and saccharopine
+relationship: negatively_regulates GO:0051975 ! L-lysine biosynthetic process via alpha-aminoadipate and saccharopine
created_by: mcc
creation_date: 2011-11-03T07:57:18Z
@@ -622607,8 +640018,8 @@
is_a: GO:2000284 ! positive regulation of amino acid biosynthetic process
is_a: GO:2001194 ! regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine
intersection_of: GO:0065007 ! biological regulation
-intersection_of: positively_regulates GO:0051975 ! lysine biosynthetic process via alpha-aminoadipate and saccharopine
-relationship: positively_regulates GO:0051975 ! lysine biosynthetic process via alpha-aminoadipate and saccharopine
+intersection_of: positively_regulates GO:0051975 ! L-lysine biosynthetic process via alpha-aminoadipate and saccharopine
+relationship: positively_regulates GO:0051975 ! L-lysine biosynthetic process via alpha-aminoadipate and saccharopine
created_by: mcc
creation_date: 2011-11-03T07:57:24Z
@@ -622762,7 +640173,6 @@
synonym: "regulation of isopentenyl diphosphate synthesis, mevalonate pathway" EXACT [GOC:obol]
is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process
is_a: GO:0019747 ! regulation of isoprenoid metabolic process
-is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0042762 ! regulation of sulfur metabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
is_a: GO:0071071 ! regulation of phospholipid biosynthetic process
@@ -622782,7 +640192,6 @@
synonym: "negative regulation of isopentenyl diphosphate anabolism, mevalonate pathway" EXACT [GOC:obol]
synonym: "negative regulation of isopentenyl diphosphate formation, mevalonate pathway" EXACT [GOC:obol]
synonym: "negative regulation of isopentenyl diphosphate synthesis, mevalonate pathway" EXACT [GOC:obol]
-is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0045827 ! negative regulation of isoprenoid metabolic process
is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
@@ -623579,9 +640988,10 @@
[Term]
id: GO:2001266
-name: Roundabout signaling pathway involved in axon guidance
+name: obsolete Roundabout signaling pathway involved in axon guidance
namespace: biological_process
-def: "Any Roundabout signaling pathway that is involved in axon guidance." [GOC:bf, PMID:14527427, PMID:21820427]
+def: "OBSOLETE. Any Roundabout signaling pathway that is involved in axon guidance." [GOC:bf, PMID:14527427, PMID:21820427]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "ROBO signaling pathway involved in axon chemotaxis" RELATED [GOC:obol]
synonym: "ROBO signaling pathway involved in axon growth cone guidance" RELATED [GOC:obol]
synonym: "ROBO signaling pathway involved in axon guidance" EXACT [GOC:obol]
@@ -623597,10 +641007,10 @@
synonym: "Roundabout signalling pathway involved in axon growth cone guidance" RELATED [GOC:obol]
synonym: "Roundabout signalling pathway involved in axon guidance" EXACT [GOC:obol]
synonym: "Roundabout signalling pathway involved in axon pathfinding" EXACT [GOC:obol]
-is_a: GO:0035385 ! Roundabout signaling pathway
-intersection_of: GO:0035385 ! Roundabout signaling pathway
-intersection_of: part_of GO:0007411 ! axon guidance
-relationship: part_of GO:0007411 ! axon guidance
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0007411
+consider: GO:0035385
created_by: bf
creation_date: 2011-12-12T03:40:20Z
@@ -623841,9 +641251,10 @@
[Term]
id: GO:2001283
-name: Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell
+name: obsolete Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell
namespace: biological_process
-def: "Any Roundabout signaling pathway that is involved in the directed movement of a muscle cell towards a tendon cell in response to an external stimulus." [GOC:bf, GOC:obol, GOC:sart, PMID:19793885]
+def: "OBSOLETE. Any Roundabout signaling pathway that is involved in the directed movement of a muscle cell towards a tendon cell in response to an external stimulus." [GOC:bf, GOC:obol, GOC:sart, PMID:19793885]
+comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
synonym: "ROBO signaling pathway involved in muscle cell attraction" RELATED [GOC:obol]
synonym: "ROBO signaling pathway involved in muscle cell chemotaxis toward tendon cell" EXACT [GOC:obol]
synonym: "ROBO signaling pathway involved in muscle cell chemotaxis towards tendon cell" EXACT [GOC:obol]
@@ -623855,10 +641266,10 @@
synonym: "Roundabout signalling pathway involved in muscle cell attraction" RELATED [GOC:obol]
synonym: "Roundabout signalling pathway involved in muscle cell chemotaxis toward tendon cell" EXACT [GOC:obol]
synonym: "Roundabout signalling pathway involved in muscle cell chemotaxis towards tendon cell" EXACT [GOC:obol]
-is_a: GO:0035385 ! Roundabout signaling pathway
-intersection_of: GO:0035385 ! Roundabout signaling pathway
-intersection_of: part_of GO:0036061 ! muscle cell chemotaxis toward tendon cell
-relationship: part_of GO:0036061 ! muscle cell chemotaxis toward tendon cell
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31254" xsd:anyURI
+is_obsolete: true
+consider: GO:0035385
+consider: GO:0036061
created_by: bf
creation_date: 2011-12-15T10:42:03Z
@@ -624238,7 +641649,6 @@
synonym: "gliotoxin catabolism" EXACT [GOC:obol]
synonym: "gliotoxin degradation" EXACT [GOC:obol]
is_a: GO:0043387 ! mycotoxin catabolic process
-is_a: GO:0043603 ! amide metabolic process
is_a: GO:0044273 ! sulfur compound catabolic process
is_a: GO:0051410 ! detoxification of nitrogen compound
created_by: pr
@@ -624254,7 +641664,6 @@
synonym: "gliotoxin formation" EXACT [GOC:obol]
synonym: "gliotoxin synthesis" EXACT [GOC:obol]
is_a: GO:0043386 ! mycotoxin biosynthetic process
-is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:0044272 ! sulfur compound biosynthetic process
relationship: has_part GO:0003839 ! gamma-glutamylcyclotransferase activity
relationship: has_part GO:0004364 ! glutathione transferase activity
@@ -624422,6 +641831,7 @@
def: "Catalysis of the reaction: an L-alpha-amino acid + cholate = an N-choloyl-L-alpha-amino acid + H2O." [PMID:38326608, PMID:38326609, PMID:40446798, RHEA:79087]
xref: RHEA:79087
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
+property_value: skos:exactMatch RHEA:79087
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30487" xsd:anyURI
created_by: dragon-ai-agent
creation_date: 2025-06-25T00:18:58Z
@@ -624433,6 +641843,7 @@
def: "Catalysis of the reaction: cholate + L-serine = L-serocholate + H2O." [PMID:38326609, RHEA:79139]
xref: RHEA:79139
is_a: GO:7770003 ! amino acid conjugated cholate hydrolase activity
+property_value: skos:exactMatch RHEA:79139
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30487" xsd:anyURI
created_by: dragon-ai-agent
creation_date: 2025-06-25T00:18:58Z
@@ -624444,6 +641855,7 @@
def: "Catalysis of the reaction: cholate + L-alanine = L-alanocholate + H2O." [PMID:38326609, RHEA:79131]
xref: RHEA:79131
is_a: GO:7770003 ! amino acid conjugated cholate hydrolase activity
+property_value: skos:exactMatch RHEA:79131
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30487" xsd:anyURI
created_by: dragon-ai-agent
creation_date: 2025-06-25T00:18:58Z
@@ -624455,6 +641867,7 @@
def: "Catalysis of the reaction: cholate + L-phenylalanine = L-phenylalanocholate + H2O." [PMID:38326608, RHEA:79123]
xref: RHEA:79123
is_a: GO:7770003 ! amino acid conjugated cholate hydrolase activity
+property_value: skos:exactMatch RHEA:79123
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30487" xsd:anyURI
created_by: dragon-ai-agent
creation_date: 2025-06-25T00:18:58Z
@@ -624466,6 +641879,7 @@
def: "Catalysis of the reaction: cholate + L-arginine = L-arginocholate + H2O." [PMID:38326608, RHEA:79111]
xref: RHEA:79111
is_a: GO:7770003 ! amino acid conjugated cholate hydrolase activity
+property_value: skos:exactMatch RHEA:79111
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30487" xsd:anyURI
created_by: dragon-ai-agent
creation_date: 2025-06-25T00:18:58Z
@@ -624477,6 +641891,7 @@
def: "Catalysis of the reaction: cholate + L-histidine = L-histidocholate + H2O." [PMID:38326608, RHEA:79099]
xref: RHEA:79099
is_a: GO:7770003 ! amino acid conjugated cholate hydrolase activity
+property_value: skos:exactMatch RHEA:79099
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30487" xsd:anyURI
created_by: dragon-ai-agent
creation_date: 2025-06-25T00:18:58Z
@@ -624538,6 +641953,235 @@
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30866" xsd:anyURI
created_by: dragon-ai-agent
+[Term]
+id: GO:7770014
+name: spermatid mitochondrial nucleoid elimination
+namespace: biological_process
+def: "The process in which spermatids lose their mitochondrial nucleoids during spermatid development. This process involves the controlled elimination of mitochondrial DNA-protein complexes while preserving the mitochondrial membranes and and contributes to maternal mitochondrial inheritance patterns by inhibiting paternal transmission." [PMID:28318978]
+synonym: "paternal mtDNA elimination" RELATED []
+synonym: "spermatid mitochondrial genome elimination" RELATED []
+synonym: "spermatid nucleoid degradation" RELATED []
+is_a: GO:0032043 ! mitochondrial DNA catabolic process
+relationship: part_of GO:0007291 ! sperm individualization
+relationship: part_of GO:0030382 ! sperm mitochondrion organization
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30344" xsd:anyURI
+created_by: dragon-ai-agent
+
+[Term]
+id: GO:7770015
+name: intermembrane lipid transporter complex
+namespace: cellular_component
+def: "A protein complex that mediates the transport of lipids between membranes, in which a lipid molecule or molecules is transferred through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane." [PMID:39106189, PMID:40269155]
+synonym: "lipid transporter complex" RELATED []
+is_a: GO:1990351 ! transporter complex
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30955" xsd:anyURI
+created_by: dragon-ai-agent
+
+[Term]
+id: GO:7770016
+name: rescue of stalled mitochondrial ribosome
+namespace: biological_process
+def: "A process of mitochondrial translational elongation that takes place when a mitochondrial ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex." [PMID:33243891]
+is_a: GO:0070125 ! mitochondrial translational elongation
+is_a: GO:0072344 ! rescue of stalled cytosolic ribosome
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30547" xsd:anyURI
+created_by: dragon-ai-agent
+
+[Term]
+id: GO:7770017
+name: plasma membrane expansion
+namespace: biological_process
+def: "A cellular process which results in an increase in the size (surface area) of the plasma membrane during cell growth or osmotic stress. This can occur by lipid transfer, membrane trafficking, or eisosome disassembly." [PMID:40629316]
+synonym: "plasma membrane biogenesis" RELATED []
+is_a: GO:0007009 ! plasma membrane organization
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30786" xsd:anyURI
+created_by: dragon-ai-agent
+
+[Term]
+id: GO:7770018
+name: positive regulation of plasma membrane expansion
+namespace: biological_process
+def: "Any process that activates or increases the frequency, rate or extent of plasma membrane expansion." [PMID:40629316]
+is_a: GO:0051130 ! positive regulation of cellular component organization
+is_a: GO:1903729 ! regulation of plasma membrane organization
+intersection_of: GO:0065007 ! biological regulation
+intersection_of: positively_regulates GO:7770017 ! plasma membrane expansion
+relationship: positively_regulates GO:7770017 ! plasma membrane expansion
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30786" xsd:anyURI
+created_by: dragon-ai-agent
+
+[Term]
+id: GO:7770019
+name: negative regulation of enteroendocrine cell differentiation
+namespace: biological_process
+def: "Any process that stops, prevents or reduces the frequency, rate or extent of enteroendocrine cell differentiation." [PMID:37883554]
+is_a: GO:0030857 ! negative regulation of epithelial cell differentiation
+intersection_of: GO:0065007 ! biological regulation
+intersection_of: negatively_regulates GO:0035883 ! enteroendocrine cell differentiation
+relationship: negatively_regulates GO:0035883 ! enteroendocrine cell differentiation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30979" xsd:anyURI
+created_by: dragon-ai-agent
+creation_date: 2025-10-31T00:00:00Z
+
+[Term]
+id: GO:7770020
+name: intestinal enterochromaffin enteroendocrine cell differentiation
+namespace: biological_process
+def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal enterochromaffin enteroendocrine cell. Enterochromaffin enteroendocrine cells are found in the gastrointestinal mucosa and secrete serotonin and some neurotransmitters including enkephalins and substance P." [PMID:37883554]
+synonym: "type EC enteroendocrine cell differentiation" EXACT []
+is_a: GO:0035883 ! enteroendocrine cell differentiation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30979" xsd:anyURI
+created_by: dragon-ai-agent
+creation_date: 2025-10-31T00:00:00Z
+
+[Term]
+id: GO:7770021
+name: intestinal type G enteroendocrine cell differentiation
+namespace: biological_process
+def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type G enteroendocrine cell. Intestinal type G enteroendocrine cells are found in the stomach and duodenum and are responsible for the secretion of gastrin and enkephalin." [PMID:37883554]
+is_a: GO:0035883 ! enteroendocrine cell differentiation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30979" xsd:anyURI
+created_by: dragon-ai-agent
+creation_date: 2025-10-31T00:00:00Z
+
+[Term]
+id: GO:7770022
+name: intestinal type I enteroendocrine cell differentiation
+namespace: biological_process
+def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type I enteroendocrine cell. Intestinal type I enteroendocrine cells are found in the duodenum and jejunum and secrete cholecystokinin." [GOC:TermGenie, PMID:37883554]
+synonym: "CCK cell differentiation" EXACT []
+is_a: GO:0035883 ! enteroendocrine cell differentiation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30979" xsd:anyURI
+created_by: dragon-ai-agent
+creation_date: 2025-10-31T00:00:00Z
+
+[Term]
+id: GO:7770023
+name: intestinal type L enteroendocrine cell differentiation
+namespace: biological_process
+def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type L enteroendocrine cell. Intestinal type L enteroendocrine cells are found in ileum and large intestine and secrete glucagon-like peptides." [PMID:37883554]
+is_a: GO:0035883 ! enteroendocrine cell differentiation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30979" xsd:anyURI
+created_by: dragon-ai-agent
+creation_date: 2025-10-31T00:00:00Z
+
+[Term]
+id: GO:7770024
+name: intestinal type N enteroendocrine cell differentiation
+namespace: biological_process
+def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type N enteroendocrine cell. Intestinal type N enteroendocrine cells are found in the ileum and jejunum and secrete neurotensin." [PMID:37883554]
+is_a: GO:0035883 ! enteroendocrine cell differentiation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30979" xsd:anyURI
+created_by: dragon-ai-agent
+creation_date: 2025-10-31T00:00:00Z
+
+[Term]
+id: GO:7770025
+name: intestinal type D enteroendocrine cell differentiation
+namespace: biological_process
+def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type D enteroendocrine cell. Intestinal type D enteroendocrine cells are found in the gastrointestinal tract and in the pancreas and secrete somatostatin." [PMID:37883554]
+is_a: GO:0035883 ! enteroendocrine cell differentiation
+is_a: GO:0061101 ! neuroendocrine cell differentiation
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30979" xsd:anyURI
+created_by: dragon-ai-agent
+creation_date: 2025-10-31T00:00:00Z
+
+[Term]
+id: GO:7770026
+name: N(6),N(6),N(6)-trimethyl-L-lysine transmembrane transporter activity
+namespace: molecular_function
+def: "Enables the transfer of N(6),N(6),N(6)-trimethyl-L-lysine from one side of a membrane to the other." [PMID:41075780, PMID:41075794]
+is_a: GO:0015179 ! L-amino acid transmembrane transporter activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30986" xsd:anyURI
+created_by: dragon-ai-agent
+
+[Term]
+id: GO:7770027
+name: dimethylarginine transmembrane transporter activity
+namespace: molecular_function
+def: "Enables the transfer of dimethylarginine from one side of a membrane to the other." [PMID:41075780, PMID:41075794]
+xref: RHEA:75047
+is_a: GO:0022857 ! transmembrane transporter activity
+property_value: skos:narrowMatch RHEA:75047
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/30986" xsd:anyURI
+created_by: dragon-ai-agent
+
+[Term]
+id: GO:7770028
+name: glycoprotein cargo receptor activity
+namespace: molecular_function
+def: "Binding specifically to a glycoprotein (cargo) to deliver it to a transport vesicle. Glycoprotein cargo receptors span membranes, binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit the cargo molecules to nascent vesicles." [PMID:41203586]
+is_a: GO:0038024 ! cargo receptor activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31038" xsd:anyURI
+created_by: dragon-ai-agent
+
+[Term]
+id: GO:7770029
+name: phosphatidylserine receptor activity
+namespace: molecular_function
+def: "Combining with phosphatidylserine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [PMID:17960135, PMID:18082433]
+is_a: GO:0004888 ! transmembrane signaling receptor activity
+relationship: has_part GO:0001786 ! phosphatidylserine binding
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31055" xsd:anyURI
+created_by: dragon-ai-agent
+
+[Term]
+id: GO:7770030
+name: rod photoreceptor phosphodiesterase 6 complex
+namespace: cellular_component
+def: "A heterotetrameric cGMP phosphodiesterase complex found in the disc membranes of rod photoreceptor outer segments. It consists of two catalytic subunits, PDE6A and PDE6B, and two inhibitory gamma-subunits, PDE6G. In response to activation by transducin, the complex hydrolyzes cyclic GMP, thereby mediating the light-induced closure of cGMP-gated ion channels during rod phototransduction." [PMID:38159849]
+synonym: "rod PDE6 complex" EXACT []
+synonym: "rod photoreceptor PDE6 complex" EXACT []
+is_a: GO:0098796 ! membrane protein complex
+relationship: part_of GO:0120202 ! rod photoreceptor disc membrane
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31081" xsd:anyURI
+created_by: dragon-ai-agent
+
+[Term]
+id: GO:7770031
+name: sodium ion sequestering activity
+namespace: molecular_function
+def: "Binding to a sodium ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active." [PMID:25689889]
+is_a: GO:0140487 ! metal ion sequestering activity
+intersection_of: GO:0140313 ! molecular sequestering activity
+intersection_of: has_part GO:0031402 ! sodium ion binding
+relationship: has_part GO:0031402 ! sodium ion binding
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31137" xsd:anyURI
+created_by: dragon-ai-agent
+
+[Term]
+id: GO:7770032
+name: tyramine transport
+namespace: biological_process
+def: "The directed movement of tyramine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tyramine is a monoamine neurotransmitter occurring predominantly in invertebrates." [PMID:15849736, PMID:32305263, PMID:9870940]
+is_a: GO:0015844 ! monoamine transport
+is_a: GO:0015850 ! organic hydroxy compound transport
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31143" xsd:anyURI
+created_by: dragon-ai-agent
+
+[Term]
+id: GO:7770033
+name: octopamine transport
+namespace: biological_process
+def: "The directed movement of octopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Octopamine is a monoamine neurotransmitter occurring predominantly in invertebrates." [PMID:15849736, PMID:32305263, PMID:9870940]
+is_a: GO:0015695 ! organic cation transport
+is_a: GO:0015850 ! organic hydroxy compound transport
+is_a: GO:0071705 ! nitrogen compound transport
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31143" xsd:anyURI
+created_by: dragon-ai-agent
+
+[Term]
+id: GO:7770034
+name: nickel-pincer nucleotide cofactor biosynthetic process
+namespace: biological_process
+def: "The chemical reactions and pathways resulting in the formation of nickel-pincer nucleotide (NPN) cofactor, also known as nickel pyridinium-3,5-bisthiocarboxylic acid mononucleotide." [PMID:24710389, PMID:27114550, PMID:33093595, PMID:39667499, PMID:39827451]
+synonym: "NPN cofactor biosynthetic process" EXACT []
+xref: MetaCyc:PWY-7928
+is_a: GO:0051191 ! prosthetic group biosynthetic process
+property_value: skos:exactMatch MetaCyc:PWY-7928
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/31252" xsd:anyURI
+created_by: dragon-ai-agent
+
[Typedef]
id: ends_during
name: ends during